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145 results on '"Wang, Fagang"'

9. A Historical Review of Outdoor Billboard Regulation in the United States: A Case Study of Highway Beautification Act of 1965.

Author

Wang Fagang and Teng Haijian

Subjects
ROADSIDE improvement, AUTOMOBILE ownership, ROAD construction, TWENTIETH century, BILLBOARDS
Abstract

Since the early 20th century, the ownership and usage of automobiles in the United States have rapidly increased, leading to large-scale highway construction. Almost simultaneously, in the context of commercial prosperity, outdoor billboards along highways continue to increase, becoming a serious problem affecting the landscape. However, this problem was not initially effectively regulated. In the 1960s, against the backdrop of the rise of environmentalism, President Johnson proposed the concept of "New Conservation" and actively promoted environmental legislation. In 1965, the Highway Beautification Act was enacted. However, after the Act's passage, the regulation of outdoor billboards faced many challenges such as insufficient funding, industry resistance, and unconstitutional accusations, ultimately failing to achieve any actual effect. In spite of this, the historical practices of regulating and governing outdoor billboards in the U.S., along with the new environmental ideas embodied in the 1965 Highway Beautification Act, remain noteworthy today. These ideas reflect Americans' pursuit of quality of life, while the Act's failure highlights the powerful influence of modern commercialism. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Recent Advances on Heteroatom-Doped Porous Carbon—Based Electrocatalysts for Oxygen Reduction Reaction.

Author

Li, Xue, Liu, Guolei, Zheng, Han, Sun, Kuizhao, Wan, Linna, Cao, Jing, Asif, Saira, Cao, Yue, Si, Weimeng, Wang, Fagang, and Bokhari, Awais

Subjects
PROTON exchange membrane fuel cells, OXYGEN reduction, TRANSITION metal catalysts, ELECTROCATALYSTS, RENEWABLE energy sources
Abstract

Polymer electrolyte membrane fuel cells are considered one of the alternatives to fossil energy sources. The slow kinetics of the oxygen reduction reaction (ORR) at the cathode and the high price of Pt-based catalysts remain one of the key challenges for the commercial viability of proton exchange membrane fuel cells. However, their high cost and susceptibility to poisoning severely limit their use for large-scale commercial applications in fuel cells. Heteroatom-doped porous carbon has attracted extensive attention from scientists due to its advantages such as high specific surface area and the properties conferred by heteroatom doping. On the one hand, we discuss a variety of current methods for the preparation of heteroatom-doped porous carbons, including the template method and the activation method. On the other hand, we discuss the application of heteroatom-doped porous carbon in Pt catalysts, transition metal catalysts and metal-free catalysts. Finally, we also present the pre-existing and challenges of heteroatoms in ORR catalysis, which will drive the development of ORR catalysts. [ABSTRACT FROM AUTHOR]

Published
2023
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40. Injectable hyperbranched poly(β-amino ester) hydrogels with on-demand degradation profiles to match wound healing processes

Author

Xu, Qian, primary, Guo, Linru, additional, A, Sigen, additional, Gao, Yongsheng, additional, Zhou, Dezhong, additional, Greiser, Udo, additional, Creagh-Flynn, Jack, additional, Zhang, Hong, additional, Dong, Yixiao, additional, Cutlar, Lara, additional, Wang, Fagang, additional, Liu, Wenguang, additional, Wang, Wei, additional, and Wang, Wenxin, additional

Published
2018
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47. A hybrid injectable hydrogel from hyperbranched PEG macromer as a stem cell delivery and retention platform for diabetic wound healing.

Author

Xu, Qian, A, Sigen, Gao, Yongsheng, Guo, Linru, Creagh-Flynn, Jack, Zhou, Dezhong, Greiser, Udo, Dong, Yixiao, Wang, Fagang, Tai, Hongyun, Liu, Wenguang, Wang, Wei, and Wang, Wenxin

Subjects
HYDROGELS, BIOCOMPATIBILITY, ETHYLENE glycol, STEM cells, IMMUNOSTAINING
Abstract

The injectable hydrogel with desirable biocompatibility and tunable properties can improve the efficacy of stem cell-based therapy. However, the development of injectable hydrogel remains a great challenge due to the restriction of crosslinking efficiency, mechanical properties, and potential toxicity. Here, we report that a new injectable hydrogel system was fabricated from hyperbranched multi-acrylated poly(ethylene glycol) macromers (HP-PEGs) and thiolated hyaluronic acid (HA-SH) and used as a stem cell delivery and retention platform. The new HP-PEGs were synthesized via in situ reversible addition fragmentation chain transfer (RAFT) polymerization using an FDA approved anti-alcoholic drug-Disulfiram (DS) as the RAFT agent precursor. HP-PEGs can form injectable hydrogels with HA-SH rapidly via thiol-ene click reaction under physiological conditions. The hydrogels exhibited stable mechanical properties, non-swelling and anti-fouling properties. Hydrogels encapsulating adipose-derived stem cells (ADSCs) have demonstrated promising regenerative capabilities such as the maintenance of ADSCs’ stemness and secretion abilities. The ADSCs embedded hydrogels were tested on the treatment of diabetic wound in a diabetic murine animal model, showing enhanced wound healing. Statement of Significance Diabetic wounds, which are a severe type of diabetes, have become one of the most serious clinical problems. There is a great promise in the delivery of adipose stem cells into wound sites using injectable hydrogels that can improve diabetic wound healing. Due to the biocompatibility of poly(ethylene glycol) diacrylate (PEGDA), we developed an in situ RAFT polymerization approach using anti-alcoholic drug-Disulfiram (DS) as a RAFT agent precursor to achieve hyperbranched PEGDA (HP-PEG). HP-PEG can form an injectable hydrogel by crosslinking with thiolated hyaluronic acid (HA-SH). ADSCs can maintain their regenerative ability and be delivered into the wound sites. Hence, diabetic wound healing process was remarkably promoted, including inhibition of inflammation, enhanced angiogenesis and re-epithelialization. Taken together, the ADSCs-seeded injectable hydrogel may be a promising candidate for diabetic wound treatment. [ABSTRACT FROM AUTHOR]

Published
2018
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