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Additional file 1: TableS1. Information on all metabolites. Table S2. Up- and downregulatedmetabolites. Table S3. RNA-sequencing profiles. Table S4. Number of up- anddownregulated differentially expressed genes. Table S5. The primers designedfor RT-qPCR.

Evaluation of the complete decay scheme and data for (225)Ac including new measurements are presented in this report; literature data available up to March 2006 are included. The half-life is determined to be 10.0+/-0.1 days. All known measured gamma-ray relative intensities have been examined; the gamma-ray emission probability of the reference gamma-ray line of 150.04 keV is recommended to be 0.693+/-0.012%. The calculated internal conversion coefficients and their uncertainties have been used to obtain the complete decay intensity balance. The other decay characteristics are calculated using the ENSDF analysis program. Finally, the new decay scheme for (225)Ac is presented.

An evaluation of the complete scheme and data for 233 Pa decay, including results of the recent measurements, is presented. Several data evaluation procedures were used in the analysis of the half-life data. The half-life has been determined to be 26.971±0.013 days. All the gamma-ray emission probabilities ever published have been examined, and the gamma-ray emission probability for the reference 312-keV γ line is recommended as 38.35±0.28%. The calculated internal conversion coefficients and their uncertainties have been used to obtain the complete decay intensity balance. Other decay characteristics have been calculated using the ENSDF analysis program. Finally, a new 233 Pa decay scheme has been built.

The purpose of this monograph, number 5 of the series, is to present the recommended values of nuclear and decay data for a wide range of radionuclides. Activity measurements for more than sixty-three of these radionuclides have already been the subject of comparisons under the auspices of the Section II (dedicated to the measurement of radionuclides) of the CCRI. The material for this monograph is now covered in seven volumes. The first two volumes contain the primary recommended data relating to half-lives, decay modes, x-rays, gamma-rays, electron emissions, alpha- and beta-particle transitions and emissions, and their uncertainties for a set of sixty-eight radionuclides, Volume 1 for those radionuclides with mass number up to and including 150 and Volume 2 for those radionuclides with mass number over 150. Volume 3 contains the equivalent data for twenty-six additional radionuclides as listed and re-evaluation for 125Sb and 153Sm. Volume 4 contains the data for a further thirty-one radionuclides with re-evaluation for 226Ra. Volume 5 includes seventeen new radionuclide evaluations and eight re-evaluations of previous data as identified in the contents pages. Volume 6 contains twenty-one new radionuclide evaluations and four re-evaluations for 64Cu, 236Np, 237Np and 239U. Volume 7 contains twenty-four new radionuclide evaluations and five re-evaluations for 67Ga, 208Tl, 228 Th, 242Cm and 244Cm. The data have been collated and evaluated by an international working group (Decay Data Evaluation Project) led by the Laboratoire National de métrologie et d'Essais - Laboratoire national Henri Becquerel (LNE-LNHB). The evaluators have agreed on the methodologies to be used and the CD-ROM included with this monograph contains the evaluators' comments for each radionuclide in addition to the data tables included in the monograph. The work involved in evaluating nuclear data is on-going and the recommended values are kept up to date on the LNE-LNHB website at http://www.nucleide.org/DDEP_WG/DDEPdata.htm

International audience; The purpose of this monograph, number 5 of the series, is to present the recommended values of nuclear and decay data for a wide range of radionuclides. Activity measurements for more than sixty-three of these radionuclides have already been the subject of comparisons under the auspices of the Section II (dedicated to the measurement of radionuclides) of the CCRI. The material for this monograph is now covered in six volumes. The first two volumes contain the primary recommended data relating to half-lives, decay modes, x-rays, gamma-rays, electron emissions, alpha- and beta-particle transitions and emissions, and their uncertainties for a set of sixty-eight radionuclides, Volume 1 for those radionuclides with mass number up to and including 150 and Volume 2 for those radionuclides with mass number over 150. Volume 3 contains the equivalent data for twenty-six additional radionuclides as listed and re-evaluation for 125Sb and 153Sm. Volume 4 contains the data for a further thirty-one radionuclides with re-evaluation for 226Ra. Volume 5 includes seventeen new radionuclide evaluations and eight re-evaluations of previous data as identified in the contents pages. Volume 6 contains twenty-one new radionuclide evaluations and four re-evaluations for 64Cu, 236Np, 237Np and 239U. The data have been collated and evaluated by an international working group (Decay Data Evaluation Project) led by the Laboratoire National de métrologie et d'Essais - Laboratoire national Henri Becquerel (LNE-LNHB). The evaluators have agreed on the methodologies to be used and the CD-ROM included with this monograph contains the evaluators' comments for each radionuclide in addition to the data tables included in the monograph. The work involved in evaluating nuclear data is on-going and the recommended values are kept up to date on the LNE-LNHB website at http://www.nucleide.org/DDEP_WG/DDEPdata.htm

Evaluation of the complete decay scheme and data for (235)U including new measurements are presented in this report; literature data available up to June 2008 are included. The half-life is determined to be (7.04+/-0.01) x 10(8) yr. All known measured gamma-ray absolute intensities have been examined; the gamma-ray emission probability of the reference gamma-ray line of 185.72 keV is recommended to be 57.0+/-0.3%. The calculated internal conversion coefficients and their uncertainties have been used to obtain the complete decay intensity balance. The other decay characteristics are calculated using the ENSDF analysis program. Finally the new decay scheme for (235)U is presented.