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2,038 results on '"Wang, Aihua"'

37. Correlation analysis of serum levels of H19 and CRP levels and ulcerative colitis

Author

Wang Aihua and Jiang Yongkang

Subjects
ulcerative colitis, h19, crp, Biochemistry, QD415-436
Abstract

Background: To elucidate clinical applications of detecting serum levels of H19 and CRP in predicting the severity of ulcerative colitis (UC). Methods: Two hundred UC patients were recruited, and classified to mild/moderate group and severe group according to the Truelove-Witts grading system. Serum levels of H19 and CRP in UC patients were detected by turbidimetric inhibition immuno assay and qRT-PCR. Differences in serum levels of H19 and CRP between mild/moderate group and severe group were analyzed. By plotting ROC curves, the diagnostic potentials of H19 and CRP in UC were evaluated. Kappa conformance test was conducted to validate the conformance of detecting serum levels of H19 and CRP to clinical diagnosis of UC. Results: Serum levels of H19 and CRP were higher in UC patients of severe group than those of mild/moderate group. Their levels were both positively correlated to the severity of UC. High sensitivity (83.3%) and specificity (80.0%), as well as the maximum Youden index (0.633) were obtained at the cut-off value for H19 level of 2.755, and AUC was 0.8835. Meanwhile, Kappa coefficient (k) was 0.760 at the cut-off value for H19 level of 2.755, showing a high conformance to clinical diagnosis of UC. In addition, acceptable sensitivity (68.49%) and high specificity (85.83%), as well as the maximum Youden index (0.543) were obtained at the cut-off value for CRP level of 6.390 mg/L, and AUC was 0.8018. k was 0.435, showing an acceptable conformance to clinical diagnosis of UC based on serum level of CRP. Conclusions: Serum levels of H19 and CRP increase with the deterioration of UC. Detecting their serum levels has a consistent result to clinical diagnosis of UC, with a superior performance of H19 than that of CRP.

Published
2023
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44. Division of Power Grid Dispatching Domain and Analysis of Operation Characteristics

Author

Wang, Shunjiang, Wang, Yifan, Wang, Tianhang, Hao, Jiancheng, Ge, Weichun, Wang, Aihua, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Chu, Shu-Chuan, editor, Lin, Jerry Chun-Wei, editor, Li, Jianpo, editor, and Pan, Jeng-Shyang, editor

Published
2022
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45. Research Progress on the Pathogenesis and Preventive Treatment of Ischemic Stroke in Breast Cancer-related Ischemic Stroke

Author

Xiaoyue SUN, Fengling WANG, Aihua WANG

Subjects
breast neoplasms, ischemic stroke, blood coagulation disorders, review, Medicine
Abstract

Breast cancer and ischemic stroke are two important diseases that endanger human health. More and more studies have shown that the incidence of breast cancer with ischemic stroke is higher than that of the general population, however, its pathogenesis, optimal treatment and prevention strategies are still unclear. This article summarized the evidence literature on the epidemiology, risk factors, clinical and imaging features, pathogenesis and prevention measures of breast cancer-related ischemic stroke, aiming to sort out the research progress of breast cancer-related ischemic stroke, as well as the potential strategies to solve the above problems.

Published
2022
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