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2,726 results on '"Wallace, T"'

1. Performance of PIP-II High-beta 650 Cryomodule After Transatlantic Shipping

Author

Ozelis, J., Barba, M., Bernardini, J., Contreras-Martinez, C., Crawford, D., Dong, J., Grzelak, V., Hanlet, P., Holzbauer, J., Jia, Y., Kazakov, S., Khabiboulline, T., Makara, J., Patel, N., Patel, V., Pei, L., Peterson, D., Pischalnikov, Y., Porwisiak, D., Ranpariya, S., Steimel, J., Solyak, N., Subedi, J., Sukhanov, A., Varghese, P., Wallace, T., White, M., Wijethunga, S., Xie, Y., and Yoon, S.

Subjects
Physics - Accelerator Physics
Abstract

After shipment to the Daresbury Lab and return to Fermilab, the prototype HB650 cryomodule underwent another phase of 2K RF testing to ascertain any performance issues that may have arisen from the transport of the cryomodule. While measurements taken at room temperature after the conclusion of shipment indicated that there were no negative impacts on cavity alignment, beamline vacuum, or cavity frequency, testing at 2K was required to validate other aspects such as tuner operation, cavity coupling, cryogenic system integrity, and cavity performance. Results of this latest round of limited 2K testing will be presented., Comment: 32nd Linear Accelerator Conference (LINAC 2024)

Published
2024

3. Wearable Devices in Healthcare: Challenges, Current Trends and a Proposition of Affordable Low Cost and Scalable Computational Environment of Internet of Things

Author

Mendonça, Fabrício Martins, Dantas, Mário A. R., Fortunato, Wallace T., Oliveira, Juan F. S., Souza, Breno C., Filgueiras, Marcelo Q., Magjarevic, Ratko, Series Editor, Ładyżyński, Piotr, Associate Editor, Ibrahim, Fatimah, Associate Editor, Lackovic, Igor, Associate Editor, Rock, Emilio Sacristan, Associate Editor, Bastos-Filho, Teodiano Freire, editor, de Oliveira Caldeira, Eliete Maria, editor, and Frizera-Neto, Anselmo, editor

Published
2022
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6. Exposure to Ambient Particulate Matter Is Associated With Accelerated Functional Decline in Idiopathic Pulmonary Fibrosis

Author

Winterbottom, Christopher J, Shah, Rupal J, Patterson, Karen C, Kreider, Maryl E, Panettieri, Reynold A, Rivera-Lebron, Belinda, Miller, Wallace T, Litzky, Leslie A, Penning, Trevor M, Heinlen, Krista, Jackson, Tara, Localio, A Russell, and Christie, Jason D

Subjects
Lung, Digestive Diseases, Autoimmune Disease, Climate-Related Exposures and Conditions, Rare Diseases, Aetiology, 2.2 Factors relating to the physical environment, Respiratory, Sustainable Cities and Communities, Good Health and Well Being, Aged, Aged, 80 and over, Air Pollution, Cohort Studies, Disease Progression, Female, Humans, Idiopathic Pulmonary Fibrosis, Male, Middle Aged, Outcome Assessment, Health Care, Particulate Matter, Time Factors, Vital Capacity, air pollution, environmental pollution, idiopathic pulmonary fibrosis, interstitial lung disease, pulmonary fibrosis, Clinical Sciences, Respiratory System
Abstract

BackgroundIdiopathic pulmonary fibrosis (IPF), a progressive disease with an unknown pathogenesis, may be due in part to an abnormal response to injurious stimuli by alveolar epithelial cells. Air pollution and particulate inhalation of matter evoke a wide variety of pulmonary and systemic inflammatory diseases. We therefore hypothesized that increased average ambient particulate matter (PM) concentrations would be associated with an accelerated rate of decline in FVC in IPF.MethodsWe identified a cohort of subjects seen at a single university referral center from 2007 to 2013. Average concentrations of particulate matter < 10 and < 2.5 μg/m3 (PM10 and PM2.5, respectively) were assigned to each patient based on geocoded residential addresses. A linear multivariable mixed-effects model determined the association between the rate of decline in FVC and average PM concentration, controlling for baseline FVC at first measurement and other covariates.ResultsOne hundred thirty-five subjects were included in the final analysis after exclusion of subjects missing repeated spirometry measurements and those for whom exposure data were not available. There was a significant association between PM10 levels and the rate of decline in FVC during the study period, with each μg/m3 increase in PM10 corresponding with an additional 46 cc/y decline in FVC (P = .008).ConclusionsAmbient air pollution, as measured by average PM10 concentration, is associated with an increase in the rate of decline of FVC in IPF, suggesting a potential mechanistic role for air pollution in the progression of disease.

Published
2018

10. Dissecting quantitative trait nucleotides by saturation genome editing

Author

Roy, Kevin R., primary, Smith, Justin D., additional, Li, Shengdi, additional, Vonesch, Sibylle C., additional, Nguyen, Michelle, additional, Burnett, Wallace T., additional, Orsley, Kevin M., additional, Lee, Cheng-Sheng, additional, Haber, James E., additional, St.Onge, Robert P., additional, and Steinmetz, Lars M., additional

Published
2024
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12. Self-perceptions of masculinities and testicular cancer: Qualitative explorations

Author

Dax, V, Ftanou, M, Tran, B, Lewin, J, Ayton, D, Seidler, Z, Wallace, T, Wiley, JF, Dax, V, Ftanou, M, Tran, B, Lewin, J, Ayton, D, Seidler, Z, Wallace, T, and Wiley, JF

Abstract

OBJECTIVE: Masculinities have been explored in men with testicular cancer (TC), though limited contemporary research is available on traditional masculine norms important to masculine self-perception. The purpose of this research was to explore the discourse of TC experience in relation to masculine self-perception. METHODS: A qualitative descriptive study was conducted consisting of semi-structured interviews with 21 men. Men were aged between 31 and 47 (Mage = 35.7). Most men were diagnosed with Stage 1 cancer (66.6%), all men had finished active treatment and time since diagnosis ranged from 17.3 to 71.8 months (M = 47.2). Independent coding was conducted by two researchers and was refined in coding meetings with authors. Themes were developed in a predominantly deductive manner, and analysis of themes was undertaken using a reflexive analysis approach. RESULTS: Traditional masculine norms showed differing relationships to masculine self-perception. Two main themes were identified [1] Maintained or enhanced masculine self-perception and [2] threats to masculine self-perception. Subthemes demonstrated that maintaining emotional control, strength and 'winning' was important to men, and reduced physical competencies (i.e., strength, sexual dysfunction, virility) challenged self-perception. Strict adherence to traditional norms in response to threatened self-perception related to psychological distress. CONCLUSION: Leveraging traditionally masculine norms such as physical strength and control and developing flexible adaptations of masculinities should be encouraged with men with TC to retain self-perception and potentially enable better coping. Masculine self-perception of gay/bisexual men may centre around sexual functioning, though further research is required.

Published
2024

23. AYIOS STEPHANOS: EXCAVATIONS AT A BRONZE AGE AND MEDIEVAL SETTLEMENT IN SOUTHERN LACONIA

Author

TAYLOUR, W. D., JANKO, R., FORTENBERRY, D., GOALEN, M. J., WALLACE, T., BANKS, E. C., BINTLIFF, J. L., BISEL, S., BLITZER, H., DUHIG, C., FRENCH, E. B., GALE, N. H., HOFFMANN, S. M. A., IJDO, M. J., JONES, G., JONES, R. E., KARDULIAS, P. N., MACGILLIVRAY, J. A., MOUNTJOY, P. A., MOURER-CHAUVIRÉ, C., NICODEMUS, A., REESE, D. S., ROBINSON, V. J., ROSE, M. J., SANDERS, G. D. R., SANDERS, J. MOTYKA, STEWART, B. H. I. H., STOS, Z. A., TOMLINSON, J. E., WHITBREAD, I. K., and ZERNER, C.

Published
2008

27. Interstitial Lung Disease in the Elderly

Author

Patterson, Karen C., Shah, Rupal J., Porteous, Mary K., Christie, Jason D., D’Errico, Carly A., Chadwick, Matthew, Triano, Matthew J., Deshpande, Charuhas, Rossman, Milton D., Litzky, Leslie A., Kreider, Maryl, and Miller, Wallace T., Jr.

Published
2017
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28. A Validated Model for the Imaging Diagnosis of Cystic Lung Disease

Author

Wallace T. Miller, Karen C. Patterson, Shweta Sood, James E. Schmitt, Arshad A. Wani, Robert Borden, Maya Galperin-Aisenberg, Mary K. Porteus, Michelle L. Hershman, Michael Hewitt, Jennifer Levy, Victor D. Babatunde, Tetiana Glushko, Timothy J. Niesen, Sergey Leshchinskiy, Karine Sahakyan, Keyur Desai, Jennifer A. Gillman, Sandeep Reddy, Michael Shriver, Nathaniel B. Linna, Abass M. Noor, Aysenur Buz, Matthew E. Biron, and Scott Simpson

Subjects
General Medicine
Published
2023
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33. Evaluating nitrogen release rates of commercial slow-release urea products using Brix value analysis: a validation study comparing two methods.

Author

Wallace, T. Fernández, Zenobi, M. G., Bollatti, J. M., Boetto, C., and Salloum, M. S.

Subjects
DISTILLED water, UREA, NITROGEN
Abstract

Copyright of Agriscientia is the property of Revista AgriScientia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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34. FOXP3+ regulatory T cells are associated with the severity and prognosis of sarcoidosis.

Author

Patterson, Karen C., Miller, Wallace T., Hancock, Wayne W., and Akimova, Tatiana

Subjects
SARCOIDOSIS, REGULATORY T cells, T cells, PROGNOSIS, LUNG volume measurements, ETIOLOGY of diseases
Abstract

Rationale: Sarcoidosis is an inflammatory granulomatous disease of unknown etiology with predominant lung involvement. Organ involvement and disease severity, as well as the nature of immune alterations, vary among patients leading to a range of clinical phenotypes and outcomes. Our objective was to evaluate the association of disease course and immune responses in pulmonary sarcoidosis. Methods: In this prospective cohort study of 30 subjects, most of whom were followed for one year, we evaluated 14 inflammatory markers in plasma, 13 Treg/T cell flow cytometry markers and 8 parameters of FOXP3+ Treg biology, including suppressive function, epigenetic features and stability. Results: We identified a set of 13 immunological parameters that differ in sarcoidosis subjects in comparison with healthy donors. Five of those were inversely correlated with suppressive function of Tregs in sarcoidosis, and six (TNFα, TNFR I and II, sCD25, Ki-67 and number of Tregs) were particularly upregulated or increased in subjects with thoracic lymphadenopathy. Treg suppressive function was significantly lower in patients with thoracic lymphadenopathy, and in patients with higher burdens of pulmonary and systemic symptoms. A combination of five inflammatory markers, Ki-67 expression, Treg function, and lung diffusion capacity evaluated at study entry predicted need for therapy at one year follow-up in 90% of cases. Conclusion: Tregs may suppress ongoing inflammation at local and systemic levels, and TNFα, TNFR I and II, sCD25 and Ki-67 emerge as attractive biomarkers for in vivo sarcoid inflammatory activity. [ABSTRACT FROM AUTHOR]

Published
2024
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37. A Validated Model for the Imaging Diagnosis of Cystic Lung Disease

Author

Miller, Wallace T., primary, Patterson, Karen C., additional, Sood, Shweta, additional, Schmitt, James E., additional, Wani, Arshad A., additional, Borden, Robert, additional, Galperin-Aisenberg, Maya, additional, Porteus, Mary K., additional, Hershman, Michelle L., additional, Hewitt, Michael, additional, Levy, Jennifer, additional, Babatunde, Victor D., additional, Glushko, Tetiana, additional, Niesen, Timothy J., additional, Leshchinskiy, Sergey, additional, Sahakyan, Karine, additional, Desai, Keyur, additional, Gillman, Jennifer A., additional, Reddy, Sandeep, additional, Shriver, Michael, additional, Linna, Nathaniel B., additional, Noor, Abass M., additional, Buz, Aysenur, additional, Biron, Matthew E., additional, and Simpson, Scott, additional

Published
2023
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48. Identification and Prognosis of Patients With Interstitial Pneumonia With Autoimmune Features

Author

Nikhil Jiwrajka, Giorgos Loizidis, Karen C. Patterson, Maryl E. Kreider, Cheilonda R. Johnson, Wallace T. Miller, Eduardo Jose Mortani Barbosa, Namrata Patel, Michael F. Beers, Leslie A. Litzky, Michael D. George, and Mary K. Porteous

Subjects
Male, Rheumatology, Myositis, Humans, Connective Tissue Diseases, Lung Diseases, Interstitial, Prognosis, Idiopathic Pulmonary Fibrosis, Autoimmune Diseases
Abstract

Background/Objective \ud Patients classified as interstitial pneumonia with autoimmune features (IPAF) have interstitial lung disease (ILD) and features of autoimmunity but do not fulfill criteria for connective tissue diseases (CTDs). Our goal was to identify patients classifiable as IPAF, CTD-ILD, and idiopathic pulmonary fibrosis (IPF) from a preexisting pulmonary cohort and evaluate the prognosis of patients with IPAF.\ud \ud Methods \ud We reviewed the medical records of 456 patients from a single-center pulmonary ILD cohort whose diagnoses were previously established by a multidisciplinary panel that did not include rheumatologists. We reclassified patients as IPAF, CTD-ILD, or IPF. We compared transplant-free survival using Kaplan-Meier methods and identified prognostic factors using Cox models.\ud \ud Results \ud We identified 60 patients with IPAF, 113 with CTD-ILD, and 126 with IPF. Transplant-free survival of IPAF was not statistically significantly different from that of CTD-ILD or IPF. Among IPAF patients, male sex (hazard ratio, 4.58 [1.77–11.87]) was independently associated with worse transplant-free survival. During follow-up, only 10% of IPAF patients were diagnosed with CTD-ILD, most commonly antisynthetase syndrome.\ud \ud Conclusion \ud Despite similar clinical characteristics, most patients with IPAF did not progress to CTD-ILD; those who did often developed antisynthetase syndrome, highlighting the critical importance of comprehensive myositis autoantibody testing in this population. As in other types of ILD, male sex may portend a worse prognosis in IPAF. The routine engagement of rheumatologists in the multidisciplinary evaluation of ILD will help ensure the accurate classification of these patients and help clarify prognostic factors.

Published
2022

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