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3. Next-generation care pathways for allergic rhinitis and asthma multimorbidity: A model for multimorbid non-communicable diseases—Meeting Report (Part 1)

Author

Bousquet, J. (Jean), Pham-Thi, N. (Nhân), Bedbrook, A. (Anna), Agache, I. (Ioana), Annesi-Maesano, I. (Isabella), Ansotegui, I.J. (I.), Anto, J.M. (Josep), Bachert, C. (Claus), Benveniste, S. (Samuel), Bewick, M. (Mike), Billo, N. (Nils), Bosnic-Anticevich, S. (Sinthia), Bosse, I. (Isabelle), Brusselle, G.G. (Guy), Calderon, M. (Moises), Canonica, G. (Gwalter), Caraballo, L.R. (L.), Cardona, D. (Doris), Carriazo, A.M. (Ana Maria), Cash, E. (Eugene), Cecchi, L. (Lorenzo), Chu, D.K. (Derek K.), Colgan, E. (Elaine), Costa, E. (Elisio), Cruz, A.A. (Alvaro), Czarlewski, W. (Wienczyslawa), Durham, S.R. (Stephen), Ebisawa, M. (Motohiro), Erhola, M. (Marina), Fauquert, J.-L. (Jean-Luc), Fokkens, W.J. (Wytske), Fonseca, J.A. (Joao A.), Guldemond, N. (Nick), Iinuma, T. (Tomohisa), Illario, M. (Maddalena), Klimek, L. (Ludger), Kuna, P. (Piotr), Kvedariene, V. (Violeta), Larenas-Linneman, D. (Désirée), Laune, D. (Daniel), Le, L.T.T. (Lan T.T.), Lourenço, O. (Olga), Malva, J.O. (Joao O.), Marien, G. (Gert), Menditto, E. (Enrica), Mullol, J. (Joaquim), Münter, L. (Lars), Okamoto, Y. (Yoshitaka), Onorato, G.L. (Gabrielle L.), Papadopoulos, N., Perala, M. (Maritta), Pfaar, O. (Oliver), Phillips, A. (Abigail), Phillips, J. (Jim), Pinnock, H. (Hilary), Portejoie, F. (Fabienne), Quinones-Delgado, P. (Pablo), Rolland, C. (Christine), Rodts, U. (Ulysse), Samolinski, B. (Boleslaw), Sanchez-Borges, M. (Mario), Schünemann, H.J. (Holger), Shamji, M. (Mohamed), Somekh, D. (David), Togias, A., Toppila-Salmi, S. (Sanna), Tsiligianni, I.G. (Ioanna G), Usmani, O. (Omar), Walker, S. (Samantha), Wallace, D. (D.), Valiulis, A. (Arunas), Van Der Kleij, R.M. (Rianne Mjj), Ventura, M.T. (Maria Teresa), Williams, S. (Sian), Yorgancioglu, A. (Arzu), Zuberbier, T. (Torsten), Bousquet, J. (Jean), Pham-Thi, N. (Nhân), Bedbrook, A. (Anna), Agache, I. (Ioana), Annesi-Maesano, I. (Isabella), Ansotegui, I.J. (I.), Anto, J.M. (Josep), Bachert, C. (Claus), Benveniste, S. (Samuel), Bewick, M. (Mike), Billo, N. (Nils), Bosnic-Anticevich, S. (Sinthia), Bosse, I. (Isabelle), Brusselle, G.G. (Guy), Calderon, M. (Moises), Canonica, G. (Gwalter), Caraballo, L.R. (L.), Cardona, D. (Doris), Carriazo, A.M. (Ana Maria), Cash, E. (Eugene), Cecchi, L. (Lorenzo), Chu, D.K. (Derek K.), Colgan, E. (Elaine), Costa, E. (Elisio), Cruz, A.A. (Alvaro), Czarlewski, W. (Wienczyslawa), Durham, S.R. (Stephen), Ebisawa, M. (Motohiro), Erhola, M. (Marina), Fauquert, J.-L. (Jean-Luc), Fokkens, W.J. (Wytske), Fonseca, J.A. (Joao A.), Guldemond, N. (Nick), Iinuma, T. (Tomohisa), Illario, M. (Maddalena), Klimek, L. (Ludger), Kuna, P. (Piotr), Kvedariene, V. (Violeta), Larenas-Linneman, D. (Désirée), Laune, D. (Daniel), Le, L.T.T. (Lan T.T.), Lourenço, O. (Olga), Malva, J.O. (Joao O.), Marien, G. (Gert), Menditto, E. (Enrica), Mullol, J. (Joaquim), Münter, L. (Lars), Okamoto, Y. (Yoshitaka), Onorato, G.L. (Gabrielle L.), Papadopoulos, N., Perala, M. (Maritta), Pfaar, O. (Oliver), Phillips, A. (Abigail), Phillips, J. (Jim), Pinnock, H. (Hilary), Portejoie, F. (Fabienne), Quinones-Delgado, P. (Pablo), Rolland, C. (Christine), Rodts, U. (Ulysse), Samolinski, B. (Boleslaw), Sanchez-Borges, M. (Mario), Schünemann, H.J. (Holger), Shamji, M. (Mohamed), Somekh, D. (David), Togias, A., Toppila-Salmi, S. (Sanna), Tsiligianni, I.G. (Ioanna G), Usmani, O. (Omar), Walker, S. (Samantha), Wallace, D. (D.), Valiulis, A. (Arunas), Van Der Kleij, R.M. (Rianne Mjj), Ventura, M.T. (Maria Teresa), Williams, S. (Sian), Yorgancioglu, A. (Arzu), and Zuberbier, T. (Torsten)

Published
2019
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4. Next-generation care pathways for allergic rhinitis and asthma multimorbidity: A model for multimorbid non-communicable diseases—Meeting Report (Part 2)

Author

Bousquet, J. (Jean), Pham-Thi, N. (Nhân), Bedbrook, A. (Anna), Agache, I. (Ioana), Annesi-Maesano, I. (Isabella), Ansotegui, I.J. (I.), Anto, J.M. (Josep), Bachert, C. (Claus), Benveniste, S. (Samuel), Bewick, M. (Mike), Billo, N. (Nils), Bosnic-Anticevich, S. (Sinthia), Bosse, I. (Isabelle), Brusselle, G.G. (Guy), Calderon, M. (Moises), Canonica, G. (Gwalter), Caraballo, L.R. (L.), Cardona, D. (Doris), Carriazo, A.M. (Ana Maria), Cash, E. (Eugene), Cecchi, L. (Lorenzo), Chu, D.K. (Derek K.), Colgan, E. (Elaine), Costa, E. (Elisio), Cruz, A.A. (Alvaro), Czarlewski, W. (Wienczyslawa), Durham, S.R. (Stephen), Ebisawa, M. (Motohiro), Erhola, M. (Marina), Fauquert, J.-L. (Jean-Luc), Fokkens, W.J. (Wytske), Fonseca, J.A. (Joao A.), Guldemond, N. (Nick), Iinuma, T. (Tomohisa), Illario, M. (Maddalena), Klimek, L. (Ludger), Kuna, P. (Piotr), Kvedariene, V. (Violeta), Larenas-Linneman, D. (Désirée), Laune, D. (Daniel), Le, L.T.T. (Lan T.T.), Lourenço, O. (Olga), Malva, J.O. (Joao O.), Marien, G. (Gert), Menditto, E. (Enrica), Mullol, J. (Joaquim), Münter, L. (Lars), Okamoto, Y. (Yoshitaka), Onorato, G.L. (Gabrielle L.), Papadopoulos, N., Perala, M. (Maritta), Pfaar, O. (Oliver), Phillips, A. (Abigail), Phillips, J. (Jim), Pinnock, H. (Hilary), Portejoie, F. (Fabienne), Quinones-Delgado, P. (Pablo), Rolland, C. (Christine), Rodts, U. (Ulysse), Samolinski, B. (Boleslaw), Sanchez-Borges, M. (Mario), Schünemann, H.J. (Holger), Shamji, M. (Mohamed), Somekh, D. (David), Togias, A., Toppila-Salmi, S. (Sanna), Tsiligianni, I.G. (Ioanna G), Usmani, O. (Omar), Walker, S. (Samantha), Wallace, D. (D.), Valiulis, A. (Arunas), Van Der Kleij, R.M. (Rianne Mjj), Ventura, M.T. (Maria Teresa), Williams, S. (Sian), Yorgancioglu, A. (Arzu), Zuberbier, T. (Torsten), Bousquet, J. (Jean), Pham-Thi, N. (Nhân), Bedbrook, A. (Anna), Agache, I. (Ioana), Annesi-Maesano, I. (Isabella), Ansotegui, I.J. (I.), Anto, J.M. (Josep), Bachert, C. (Claus), Benveniste, S. (Samuel), Bewick, M. (Mike), Billo, N. (Nils), Bosnic-Anticevich, S. (Sinthia), Bosse, I. (Isabelle), Brusselle, G.G. (Guy), Calderon, M. (Moises), Canonica, G. (Gwalter), Caraballo, L.R. (L.), Cardona, D. (Doris), Carriazo, A.M. (Ana Maria), Cash, E. (Eugene), Cecchi, L. (Lorenzo), Chu, D.K. (Derek K.), Colgan, E. (Elaine), Costa, E. (Elisio), Cruz, A.A. (Alvaro), Czarlewski, W. (Wienczyslawa), Durham, S.R. (Stephen), Ebisawa, M. (Motohiro), Erhola, M. (Marina), Fauquert, J.-L. (Jean-Luc), Fokkens, W.J. (Wytske), Fonseca, J.A. (Joao A.), Guldemond, N. (Nick), Iinuma, T. (Tomohisa), Illario, M. (Maddalena), Klimek, L. (Ludger), Kuna, P. (Piotr), Kvedariene, V. (Violeta), Larenas-Linneman, D. (Désirée), Laune, D. (Daniel), Le, L.T.T. (Lan T.T.), Lourenço, O. (Olga), Malva, J.O. (Joao O.), Marien, G. (Gert), Menditto, E. (Enrica), Mullol, J. (Joaquim), Münter, L. (Lars), Okamoto, Y. (Yoshitaka), Onorato, G.L. (Gabrielle L.), Papadopoulos, N., Perala, M. (Maritta), Pfaar, O. (Oliver), Phillips, A. (Abigail), Phillips, J. (Jim), Pinnock, H. (Hilary), Portejoie, F. (Fabienne), Quinones-Delgado, P. (Pablo), Rolland, C. (Christine), Rodts, U. (Ulysse), Samolinski, B. (Boleslaw), Sanchez-Borges, M. (Mario), Schünemann, H.J. (Holger), Shamji, M. (Mohamed), Somekh, D. (David), Togias, A., Toppila-Salmi, S. (Sanna), Tsiligianni, I.G. (Ioanna G), Usmani, O. (Omar), Walker, S. (Samantha), Wallace, D. (D.), Valiulis, A. (Arunas), Van Der Kleij, R.M. (Rianne Mjj), Ventura, M.T. (Maria Teresa), Williams, S. (Sian), Yorgancioglu, A. (Arzu), and Zuberbier, T. (Torsten)

Published
2019
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5. Next-generation ARIA care pathways for rhinitis and asthma: A model for multimorbid chronic diseases

Author

Bousquet, J.J. (J. Jean), Schünemann, H.J. (Holger), Togias, A., Erhola, M. (Marina), Hellings, P.W. (Peter), Zuberbier, T. (Torsten), Agache, I. (Ioana), Ansotegui, I.J. (I.), Anto, J.M. (Josep), Bachert, C. (Claus), Becker, S. (Sven), Bedolla-Barajas, M. (Martin), Bewick, M. (Michael), Bosnic-Anticevich, S. (Sinthia), Bosse, I. (Isabelle), Boulet, L.P., Bourrez, J.M. (Jean Marc), Brusselle, G.G. (Guy), Chavannes, N.H. (Nicolas), Costa, E. (Elisio), Cruz, A.A. (Alvaro), Czarlewski, W. (Wienczyslawa), Fokkens, W.J. (Wytske), Fonseca, J.A. (Joao A.), Gaga, M. (Mina), Haahtela, T. (Tari), Illario, M. (Maddalena), Klimek, L. (Ludger), Kuna, P. (Piotr), Kvedariene, V. (Violeta), Le, L.T., Larenas-Linnemann, D. (Désirée), Laune, D. (Daniel), Lourenço, O.M. (Olga M.), Menditto, E. (Enrica), Mullol, J. (Joaquin), Okamoto, Y. (Yashitaka), Papadopoulos, N., Pham-Thi, N. (Nhân), Picard, R. (Robert), Pinnock, H. (Hilary), Roche, N. (Nicolas), Roller-Wirnsberger, R.E. (Regina E.), Rolland, C. (Christine), Samolinski, B. (Boleslaw), Sheikh, A. (Aziz), Toppila-Salmi, S. (Sanna), Tsiligianni, I.G. (Ioanna G), Valiulis, A. (Arunas), Valovirta, E. (Erkka), Vasankari, T. (Tuula), Ventura, M.-T. (Maria-Teresa), Walker, S. (Samantha), Williams, S. (Sian), Akdis, C.A. (Cezmi A.), Annesi-Maesano, I. (Isabella), Arnavielhe, S. (Sylvie), Basagaña, X. (Xavier), Bateman, E.D. (Eric), Bedbrook, A. (Anna), Bennoor, K.S. (K.), Benveniste, S. (Samuel), Bergmann, K.-C. (Karl-Christian), Bialek, S. (Slawomir), Billo, N. (Nils), Bindslev-Jensen, C. (Carsten), Bjermer, L. (Leif), Blain, H. (Hubert), Bonini, M. (Matteo), Bonniaud, P. (Philippe), Bouchard, J. (Jacques), Briedis, V. (Vitalis), Brightling, C.E. (Christofer E.), Brozek, J., Buhl, R. (Roland), Buonaiuto, R. (Roland), Canonica, G.W. (Giorgo W.), Cardona, D. (Doris), Carriazo, A.M. (Ana M.), Carr, W.W. (Warner), Cartier, C. (Christine), Casale, T.B. (Thomas), Cecchi, L. (Lorenzo), Cepeda Sarabia, A.M. (Alfonso M.), Chkhartishvili, E. (Eka), Chu, D.K. (Derek K.), Cingi, C. (Cemal), Colgan, E. (Elaine), De Sousa, J.C. (Jaime Correia), Courbis, A.L. (Anne Lise), Custovic, A. (Adnan), Cvetkosvki, B. (Biljana), Damato, G. (Gennaro), Da Silva, J. (Jane), Dantas, C. (Carina), Dokic, D. (D.), Dauvilliers, Y. (Yves), Dedeu, A. (Antoni), De Feo, G. (Giulia), Devillier, P. (Philippe), Di Capua, S. (Stefania), Dykewickz, M. (Marc), Dubakiene, R. (R.), Ebisawa, M. (Motohiro), El-Gamal, Y. (Y.), Eller, E. (Esben), Emuzyte, R., Farrell, J. (John), Fink-Wagner, A. (Antjie), Fiocchi, A. (Alessandro), Fontaine, J.F. (Jean F.), Gemicioǧlu, B. (Bilun), Schmid-Grendelmeir, P. (Peter), Gamkrelidze, A. (Amiran), Garcia-Aymerich, J. (Judith), Gomez, M. (Maximiliano), Diaz, S.G. (Sandra González), Gotua, M. (M.), Guldemond, N. (Nick), Guzmán, M.A. (M.), Hajjam, J. (Jawad), O'Hourihane, J.B. (John B.), Humbert, M. (Marc), Iaccarino, G. (Guido), Ierodiakonou, D. (Despo), Ivancevich, J.C. (Juan), Joos, G.F. (Guy), Jung, K.-S. (Ki-Suck), Jutel, M. (M.), Kaidashev, I. (Igor), Kalayci, O. (Omer), Kardas, P. (Przemyslaw), Keil, M. (Mark), Khaitov, M. (Mussa), Khaltaev, N., Kleine-Tebbe, J. (Jörg), Kowalski, M.L., Kritikos, V. (Vicky), Kull, C.A. (Christian), Leonardini, L. (Lisa), Lieberman, A.P. (Andrew), Lipworth, B., Lødrup Carlsen, K.C. (K. C.), Loureiro, C.C. (Claudia C.), Louis, R. (Renaud), Mair, A. (Alpana), Marien, G. (Gert), Mahboub, B., Malva, J. (Joao), Manning, P. (Patrick), De Manuel Keenoy, E. (Esteban), Marshall, G.D., Masjedi, M.R. (Mohamed R.), Maspero, J.F. (Jorge F.), Mathieu-Dupas, E. (Eve), Matricardi, P.M. (Poalo M.), Melén, E. (Eric), Melo-Gomes, E. (Elisabete), Meltzer, E.O., Mercier, J. (Jacques), Miculinic, N. (Neven), Mihaltan, F. (Florin), Milenkovic, B. (Branislava), Moda, G. (Giuliana), Mogica-Martinez, M.-D. (Maria-Dolores), Mohammad, Y., Montefort, S. (Steve), Monti, R. (Ricardo), Morais-Almeida, M. (Mario), Mösges, R. (Ralph), Münter, L. (Lars), Muraro, A. (Antonella), Murray, R. (Ruth), Naclerio, R., Napoli, L. (Luigi), Namazova-Baranova, L. (Leila), Neffen, H. (Hugo), Nekam, K. (Kristoff), Neou, A. (A.), Novellino, E. (Enrico), Nyembue, D. (Dieudonné), O'Hehir, R. (Robin), Ohta, K., Okubo, K. (Kimi), Onorato, G. (Gabrielle), Ouedraogo, S., Pali-Schöll, I. (I.), Palkonen, S. (Susanna), Panzner, P. (P.), Park, H.-S. (Hae-Sim), Pépin, J.-L. (Jean-Louis), Pereira, A.-M. (Ana-Maria), Pfaar, O. (Oliver), Paulino, E. (Ema), Phillips, J. (Jim), Plavec, D. (Davor), Popov, T.A. (Ted A.), Portejoie, F. (Fabienne), Price, D. (David), Prokopakis, E.P. (Emmanuel P.), Pugin, B. (Benoit), Raciborski, F. (Filip), Rajabian-Söderlund, R. (Rojin), Reitsma, S. (Sietze), Rodo, X. (Xavier), Romano, A., Rosario, N. (Nelson), Rottem, M. (Menahenm), Ryan, D. (Dermot), Salimäki, J. (Johanna), Sanchez-Borges, M.M. (Mario M.), Sisul, J.C. (J.), Solé, D. (Dirceu), Somekh, D. (David), Sooronbaev, T. (Talant), Sova, M. (Milan), Spranger, O., Stellato, C. (Cristina), Stelmach, R. (Rafael), Ulrik, C.S., Thibaudon, M. (Michel), To, T. (Teresa), Todo Bom, A., Tomazic, P.V. (Peter V.), Valero, A.A. (Antonio A.), Valenta, R. (Rudolph), Valentin-Rostan, M. (Marylin), Van Der Kleij, R.M. (Rianne Mjj), Vandenplas, O. (Olivier), Vezzani, G. (Giorgio), Viart, F. (Frédéric), Viegi, G., Wallace, D. (D.), Wagenmann, M. (Martin), Wang, D.Y. (De Y.), Waserman, S. (Susan), Wickman, M. (Magnus), Williams, D., Wong, G. (G.), Wroczynski, P. (Piotr), Yiallouros, P.K. (P.), Yorgancioglu, A. (Arzu), Yusuf, O.M. (Osman), Zar, H.J. (Heahter J.), Zeng, S. (Stéphane), Zernotti, M., Zhang, L. (Luo), Zhong, N.S. (Nan S.), Zidarn, M. (Mihaela), Bousquet, J.J. (J. Jean), Schünemann, H.J. (Holger), Togias, A., Erhola, M. (Marina), Hellings, P.W. (Peter), Zuberbier, T. (Torsten), Agache, I. (Ioana), Ansotegui, I.J. (I.), Anto, J.M. (Josep), Bachert, C. (Claus), Becker, S. (Sven), Bedolla-Barajas, M. (Martin), Bewick, M. (Michael), Bosnic-Anticevich, S. (Sinthia), Bosse, I. (Isabelle), Boulet, L.P., Bourrez, J.M. (Jean Marc), Brusselle, G.G. (Guy), Chavannes, N.H. (Nicolas), Costa, E. (Elisio), Cruz, A.A. (Alvaro), Czarlewski, W. (Wienczyslawa), Fokkens, W.J. (Wytske), Fonseca, J.A. (Joao A.), Gaga, M. (Mina), Haahtela, T. (Tari), Illario, M. (Maddalena), Klimek, L. (Ludger), Kuna, P. (Piotr), Kvedariene, V. (Violeta), Le, L.T., Larenas-Linnemann, D. (Désirée), Laune, D. (Daniel), Lourenço, O.M. (Olga M.), Menditto, E. (Enrica), Mullol, J. (Joaquin), Okamoto, Y. (Yashitaka), Papadopoulos, N., Pham-Thi, N. (Nhân), Picard, R. (Robert), Pinnock, H. (Hilary), Roche, N. (Nicolas), Roller-Wirnsberger, R.E. (Regina E.), Rolland, C. (Christine), Samolinski, B. (Boleslaw), Sheikh, A. (Aziz), Toppila-Salmi, S. (Sanna), Tsiligianni, I.G. (Ioanna G), Valiulis, A. (Arunas), Valovirta, E. (Erkka), Vasankari, T. (Tuula), Ventura, M.-T. (Maria-Teresa), Walker, S. (Samantha), Williams, S. (Sian), Akdis, C.A. (Cezmi A.), Annesi-Maesano, I. (Isabella), Arnavielhe, S. (Sylvie), Basagaña, X. (Xavier), Bateman, E.D. (Eric), Bedbrook, A. (Anna), Bennoor, K.S. (K.), Benveniste, S. (Samuel), Bergmann, K.-C. (Karl-Christian), Bialek, S. (Slawomir), Billo, N. (Nils), Bindslev-Jensen, C. (Carsten), Bjermer, L. (Leif), Blain, H. (Hubert), Bonini, M. (Matteo), Bonniaud, P. (Philippe), Bouchard, J. (Jacques), Briedis, V. (Vitalis), Brightling, C.E. (Christofer E.), Brozek, J., Buhl, R. (Roland), Buonaiuto, R. (Roland), Canonica, G.W. (Giorgo W.), Cardona, D. (Doris), Carriazo, A.M. (Ana M.), Carr, W.W. (Warner), Cartier, C. (Christine), Casale, T.B. (Thomas), Cecchi, L. (Lorenzo), Cepeda Sarabia, A.M. (Alfonso M.), Chkhartishvili, E. (Eka), Chu, D.K. (Derek K.), Cingi, C. (Cemal), Colgan, E. (Elaine), De Sousa, J.C. (Jaime Correia), Courbis, A.L. (Anne Lise), Custovic, A. (Adnan), Cvetkosvki, B. (Biljana), Damato, G. (Gennaro), Da Silva, J. (Jane), Dantas, C. (Carina), Dokic, D. (D.), Dauvilliers, Y. (Yves), Dedeu, A. (Antoni), De Feo, G. (Giulia), Devillier, P. (Philippe), Di Capua, S. (Stefania), Dykewickz, M. (Marc), Dubakiene, R. (R.), Ebisawa, M. (Motohiro), El-Gamal, Y. (Y.), Eller, E. (Esben), Emuzyte, R., Farrell, J. (John), Fink-Wagner, A. (Antjie), Fiocchi, A. (Alessandro), Fontaine, J.F. (Jean F.), Gemicioǧlu, B. (Bilun), Schmid-Grendelmeir, P. (Peter), Gamkrelidze, A. (Amiran), Garcia-Aymerich, J. (Judith), Gomez, M. (Maximiliano), Diaz, S.G. (Sandra González), Gotua, M. (M.), Guldemond, N. (Nick), Guzmán, M.A. (M.), Hajjam, J. (Jawad), O'Hourihane, J.B. (John B.), Humbert, M. (Marc), Iaccarino, G. (Guido), Ierodiakonou, D. (Despo), Ivancevich, J.C. (Juan), Joos, G.F. (Guy), Jung, K.-S. (Ki-Suck), Jutel, M. (M.), Kaidashev, I. (Igor), Kalayci, O. (Omer), Kardas, P. (Przemyslaw), Keil, M. (Mark), Khaitov, M. (Mussa), Khaltaev, N., Kleine-Tebbe, J. (Jörg), Kowalski, M.L., Kritikos, V. (Vicky), Kull, C.A. (Christian), Leonardini, L. (Lisa), Lieberman, A.P. (Andrew), Lipworth, B., Lødrup Carlsen, K.C. (K. C.), Loureiro, C.C. (Claudia C.), Louis, R. (Renaud), Mair, A. (Alpana), Marien, G. (Gert), Mahboub, B., Malva, J. (Joao), Manning, P. (Patrick), De Manuel Keenoy, E. (Esteban), Marshall, G.D., Masjedi, M.R. (Mohamed R.), Maspero, J.F. (Jorge F.), Mathieu-Dupas, E. (Eve), Matricardi, P.M. (Poalo M.), Melén, E. (Eric), Melo-Gomes, E. (Elisabete), Meltzer, E.O., Mercier, J. (Jacques), Miculinic, N. (Neven), Mihaltan, F. (Florin), Milenkovic, B. (Branislava), Moda, G. (Giuliana), Mogica-Martinez, M.-D. (Maria-Dolores), Mohammad, Y., Montefort, S. (Steve), Monti, R. (Ricardo), Morais-Almeida, M. (Mario), Mösges, R. (Ralph), Münter, L. (Lars), Muraro, A. (Antonella), Murray, R. (Ruth), Naclerio, R., Napoli, L. (Luigi), Namazova-Baranova, L. (Leila), Neffen, H. (Hugo), Nekam, K. (Kristoff), Neou, A. (A.), Novellino, E. (Enrico), Nyembue, D. (Dieudonné), O'Hehir, R. (Robin), Ohta, K., Okubo, K. (Kimi), Onorato, G. (Gabrielle), Ouedraogo, S., Pali-Schöll, I. (I.), Palkonen, S. (Susanna), Panzner, P. (P.), Park, H.-S. (Hae-Sim), Pépin, J.-L. (Jean-Louis), Pereira, A.-M. (Ana-Maria), Pfaar, O. (Oliver), Paulino, E. (Ema), Phillips, J. (Jim), Plavec, D. (Davor), Popov, T.A. (Ted A.), Portejoie, F. (Fabienne), Price, D. (David), Prokopakis, E.P. (Emmanuel P.), Pugin, B. (Benoit), Raciborski, F. (Filip), Rajabian-Söderlund, R. (Rojin), Reitsma, S. (Sietze), Rodo, X. (Xavier), Romano, A., Rosario, N. (Nelson), Rottem, M. (Menahenm), Ryan, D. (Dermot), Salimäki, J. (Johanna), Sanchez-Borges, M.M. (Mario M.), Sisul, J.C. (J.), Solé, D. (Dirceu), Somekh, D. (David), Sooronbaev, T. (Talant), Sova, M. (Milan), Spranger, O., Stellato, C. (Cristina), Stelmach, R. (Rafael), Ulrik, C.S., Thibaudon, M. (Michel), To, T. (Teresa), Todo Bom, A., Tomazic, P.V. (Peter V.), Valero, A.A. (Antonio A.), Valenta, R. (Rudolph), Valentin-Rostan, M. (Marylin), Van Der Kleij, R.M. (Rianne Mjj), Vandenplas, O. (Olivier), Vezzani, G. (Giorgio), Viart, F. (Frédéric), Viegi, G., Wallace, D. (D.), Wagenmann, M. (Martin), Wang, D.Y. (De Y.), Waserman, S. (Susan), Wickman, M. (Magnus), Williams, D., Wong, G. (G.), Wroczynski, P. (Piotr), Yiallouros, P.K. (P.), Yorgancioglu, A. (Arzu), Yusuf, O.M. (Osman), Zar, H.J. (Heahter J.), Zeng, S. (Stéphane), Zernotti, M., Zhang, L. (Luo), Zhong, N.S. (Nan S.), and Zidarn, M. (Mihaela)

Abstract

Background: In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy. Main body: As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhi-nitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted "patient activation", (ii) Implementation of care pathways by pharmacists and (iii) Next-generation guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG Santé as a Good Practice in the field of digitally-enabled, integrated, person-centred care. Conclusion: In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement.

Published
2019
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6. MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence

Author

Bousquet, J. (Jean), Arnavielhe, S, Bedbrook, A. (Anna), Bewick, M, Laune, D, Mathieu-Dupas, E., Murray, R., Onorato, G.L., Pépin, J.L., Picard, R., Portejoie, F, Costa, E., Fonseca, J., Lourenço, O., Morais-Almeida, M. (Mario), Todo Bom, A., Cruz, A.A. (Alvaro), Silva, J.D., Serpa, F.S., Illario, M., Menditto, E., Cecchi, L., Monti, R., Napoli, L., Ventura, M. T., De Feo, G., Larenas-Linnemann, D. (Désirée), Perez, M, Huerta Villabolos, Y.R., Rivero-yeverino, D., Rodriguez-zagal, E., Amat, F., Annesi-Maesano, I. (Isabella), Bosse, I, Demoly, P., Devillier, P. (Philippe), Fontaine, J.F., Just, P.M., Kuna, T.P., Samolinski, B. (Boleslaw), Valiulis, A. (Arunas), Emuzyte, R., Kvedariene, V. (Violeta), Ryan, D. (Dermot), Sheikh, A. (Aziz), Schmidt-grendelmeier, P., Klimek, L., Pfaar, O, Bergmann, K.-C. (Karl-Christian), Mösges, R., Zuberbier, T. (Torsten), Roller-Wirnsberger, R.E., Tomazic, P., Fokkens, WJ, Chavannes, N.H. (Nicolas), Reitsma, S., Anto, JM, Cardona, V, Dedeu, T, Mullol, J., Haahtela, T. (Tari), Salimäki, J., Toppila-Salmi, S., Valovirta, E. (Erkka), Gemicioğlu, B., Yorgancioglu, A., Papadopoulos, N., Prokopakis, E.P., Bosnic-Anticevich, S, O’hehir, R., Ivancevich, J.C. (Juan), Neffen, H, Zernotti, E., Kull, C.A. (Christian), Melén, E. (Erik), Wickman, M., Bachert, C. (Claus), Hellings, P, Palkonen, S., Bindslev-Jensen, C. (Carsten), Eller, E., Waserman, S., Sova, M., Vries, G. (Gerard) de, Eerd, M. (Maarten) van, Agache, I., Casale, T, Dykewickz, M., Naclerio, RN, Okamoto, Y., Wallace, D.V., Hellings, P.W. (Peter), Aberer, W. (W.), Akdis, C.A., Alberti, M.R., Almeida, R., Angles, R., Ansotegui, I.J. (I.), Arnavielle, S., Asayag, E., Asarnoj, A., Arshad, H, Avolio, F., Bacci, E., Baiardini, I. (Ilaria), Barbara, C, Barbagallo, M., Baroni, I., Barreto, B.A., Basagaña, X. (Xavier), Bateman, E.D. (Eric), Bedolla-Barajas, M., Beghé, B., Bel, E.H., Bennoor, K.S. (K.), Benson, M. 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(Juha), Kardas, P., Keil, M. (Mark), Keith, P.K., Khaitov, M., Khaltaev, N., Kleine-Tebbe, J., Kowalski, M.L., Kuitunen, M., Kuna, P. (Piotr), Kupczyk, M, Krzych-Fałta, E., Lacwik, P., Lauri, D., Lavrut, J., Le, L.T., Lessa, M., Levato, G., Li, J., Lieberman, A.P. (Andrew), Lipiec, A., Lipworth, B., Lodrup Carlsen, K.C., Louis, R, Luna-Pech, J.A., Maciej, K., Magnan, A, Mahboub, B., Maier, D., Mair, A., Majer, I.M. (Istvan), Malva, J., Mandajieva, E., Manning, P, De Manuel Keenoy, E., Marshall, G.D., Masjedi, M.R. (M.), Maspero, JF, Matta Campos, J.J., Matos, A.L., Maurer, M., Mavale-Manuel, S., Mayora, O., Medina-Avalos, M.A., Melén, E., Melo-Gomes, E, Meltzer, E.O., Mercier, J, Miculinic, N, Mihaltan, F. (F.), Milenkovic, B, Moda, G., Mogica-Martinez, M.D., Mohammad, Y., Momas, I. (I.), Montefort, S., Mora Bogado, D., Morato-Castro, F.F., Mota-Pinto, A., Moura Santo, P., Münter, L., Murarol, A. (Antonella), Naclerio, R., Nadif, R. (Rachel), Nalin, M., Namazova-Baranova, L. (L.), Niedeberger, V., Nekam, K., Neou, A. (A.), Nieto, A. (Antonio), Nogueira-Silva, L., Nogues, M., Novellino, E., Nyembue, T.D. (T.), O’hehir, R.E., Odzhakova, C., Ohta, K. (Ken), Okubo, K. (K.), Ortega Cisneros, M., Ouedraogo, S., Pali-Schöll, I., Panzner, P. (P.), Park, H.S. (H.), Papi, A, Passalacqua, G. (Giovanni), Paulino, E., Pawankar, R. (Ruby), Pedersen, S., Pereira, A.M. (A.), Persico, M., Phillips, J., Pigearias, B. (B.), Pin, I. (Isabelle), Pitsios, C, Plavec, D, Pohl, W. (W.), Popov, T.A., Potter, P., Pozzi, A.C., Price, D., Puy, R., Pugin, B., Pulido Ross, R.E., Przemecka, M., Rabe, K.F. (Klaus F.), Raciborski, F, Rajabian-Soderlund, R., Ribeirinho, I., Rimmer, J., Rizzo, J.A., Rizzo, M.C., Robalo-Cordeiro, C, Rodenas, F, Rodo, X., González, M. (Marcos), Rodriguez-Mañas, L., Rolland, C, Rodrigues Valle, S., Rodriguez, M.M. (M. Mirta), Romano, A., Rolla, G., Romano, M. (Matteo), Rosado-Pinto, J., Rosario, K. (Karyna), Rottem, M. (M.), Sagara, H., Sanchez-Borges, M., Sastre-Dominguez, J., Scadding, G.K., Schunemann, HJ, Scichilone, N., Schmid-Grendelmeier, P, Shamai, S., Sierra, M., Simons, F.E.R., Siroux, V. (V.), Sisul, J.C. (J.), Skrindo, I, Solé, D., Somekh, D., Sondermann, M., Sooronbaev, T, Sørensen, M. (Mette), Sorlini, M., Spranger, O., Stellato, C., Stelmach, R, Stukas, R., Sunyer, J. (Jordi), Strozek, J., Szylling, A., Tebyriçá, J.N., Thibaudon, M., To, M.S., Tomazic, P.V., Trama, U., Triggiani, M. (M.), Suppli Ulrik, C., Urrutia-Pereira, M., Valenta, R., Valero, A., Ganse, E. (Éric), Van Hague, M., Vandenplas, O. (Olivier), Vezzani, G, Vasankari, T, Vatrella, A., Verissimo, M.T., Viart, F., Viegi, G., Vicheva, D., Vontetsianos, T., Wagenmann, M, Walker, S., Wallace, D. (D.), Wang, D.Y. (De Yun), Werfel, T., Westman, M. (Mina), Williams, DM, Williams, S. (Stephanie), Wilson, N., Wright, J. (Juliet), Wroczynski, P., Yakovliev, P., Yawn, B.P. (Barbara), Yiallouros, P.K. (P.), Yusuf, O.M. (Osman), Zar, H.J., Zhang, L. (Lingling), Zhong, N., Zernotti, M., Zidarn, M. (M.), Zubrinich, C., and Zurkuhlen, A.

Abstract

mHealth, such as apps running on consumer smart devices is becoming increasingly popular and has the potential to profoundly afect healthcare and health outcomes. However, it may be disruptive and results achieved are not always reaching the goals. Allergic Rhinitis and its Impact on Asthma (ARIA) has evolved from a guideline using the best evidence-based approach to care pathways suited to real-life using mobile technology in allergic rhinitis (AR) and asthma multimorbidity. Patients largely use over-the-counter medications dispensed in pharmacies. Shared decision making centered around the patient and based on self-management should be the norm. Mobile Airways Sentinel networK (MASK), the Phase 3 ARIA initiative, is based on the freely available MASK app (the Allergy Diary, Android and iOS platforms). MASK is available in 16 languages and deployed in 23 countries. The present paper provides an over‑ view of the methods used in MASK and the key results obtained to date. These include a novel phenotypic charac‑ terization of the patients, confrmation of the impact of allergic rhinitis on work productivity and treatment patterns in real life. Most patients appear to self-medicate, are often non-adherent and do not follow guidelines. Moreover, the Allergy Diary is able to distinguish between AR medications. The potential usefulness of MASK will be further explored by POLLAR (Impact of Air Pollution on Asthma and Rhinitis), a new Horizon 2020 project using the Allergy Diary.

Published
2018
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14. A Population-based, Multifaceted Strategy to Implement Antenatal Corticosteroid Treatment Versus Standard Care for the Reduction of Neonatal Mortality Due to Preterm Birth in Low-income and Middle-income Countries

Author

Althabe, F., primary, Belizán, J. M., additional, McClure, E. M., additional, Hemingway-Foday, J., additional, Berrueta, M., additional, Mazzoni, A., additional, Ciganda, A., additional, Goudar, S. S., additional, Kodkany, B. S., additional, Mahantshetti, N. S., additional, Dhaded, S. M., additional, Katageri, G. M., additional, Metgud, M. C., additional, Joshi, A. M., additional, Bellad, M. B., additional, Honnungar, N. V., additional, Derman, R. J., additional, Saleem, S., additional, Pasha, O., additional, Ali, S., additional, Hasnain, F., additional, Goldenberg, R. L., additional, Esamai, F., additional, Nyongesa, P., additional, Ayunga, S., additional, Liechty, E. A., additional, Garces, A. L., additional, Figueroa, L., additional, Hambidge, K. M., additional, Krebs, N. F., additional, Patel, A., additional, Bhandarkar, A., additional, Waikar, M., additional, Hibberd, P. L., additional, Chomba, E., additional, Carlo, W. A., additional, Mwiche, A., additional, Chiwila, M., additional, Manasyan, A., additional, Pineda, S., additional, Meleth, S., additional, Thorsten, V., additional, Stolka, K., additional, Wallace, D. D., additional, Koso-Thomas, M., additional, Jobe, A. H., additional, and Buekens, P. M., additional

Published
2016
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18. Smoking status as a vital sign.

Author

Ahluwalia, Jasjit S., Gibson, Cheryl A., Kenney, R. Emmet, Wallace, Dennis D., Resnicow, Ken, Ahluwalia, J S, Gibson, C A, Kenney, R E, Wallace, D D, and Resnicow, K

Subjects
SMOKING, NICOTINE addiction treatment, SMOKING prevention, BLACK people, CHI-squared test, COMPARATIVE studies, COUNSELING, HEALTH status indicators, RESEARCH methodology, MEDICAL cooperation, PHYSICAL diagnosis, PHYSICIAN-patient relations, RESEARCH, RESEARCH funding, SMOKING cessation, CITY dwellers, LOGISTIC regression analysis, EVALUATION research
Abstract

Objective: We conducted this study to determine if a smoking status stamp would prompt physicians to increase the number of times they ask, advise, assist, and arrange follow-up for African-American patients about smoking-related issues.Design: An intervention study with a posttest assessment (after the physician visit) conducted over four 1-month blocks. The control period was the first 2 weeks of each month, while the following 2 weeks served as the intervention period.Setting: An adult walk-in clinic in a large inner-city hospital.Participants: We consecutively enrolled into the study 2,595 African-American patients (1,229 intervention and 1, 366 control subjects) seen by a housestaff physician.Interventions: A smoking status stamp placed on clinic charts during the intervention period.Main Results: Forty-five housestaff rotated through the clinic in 1-month blocks. In univariate analyses, patients were significantly more likely to be asked by their physicians if they smoke cigarettes during the intervention compared with the control period, 78.4% versus 45.6% (odds ratio [OR] 4.28; 95% confidence interval [CI] 3.58, 5.10). Patients were also more likely to be told by their physician to quit, 39.9% versus 26.9% (OR 1.81; 95% CI 1.36, 2.40), and have follow-up arranged, 12.3% versus 6.2% (OR 2.16; 95% CI 1.30, 3.38).Conclusions: The stamp had a significant effect on increasing rates of asking about cigarette smoking, telling patients to quit, and arranging follow-up for smoking cessation. However, the stamp did not improve the low rate at which physicians offered patients specific advice on how to quit or in setting a quit date. [ABSTRACT FROM AUTHOR]

Published
1999
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25. Routine antenatal ultrasound in low- and middle-income countries: first look - a cluster randomised trial.

Author

Goldenberg RL, Nathan RO, Swanson D, Saleem S, Mirza W, Esamai F, Muyodi D, Garces AL, Figueroa L, Chomba E, Chiwala M, Mwenechanya M, Tshefu A, Lokangako A, Bolamba VL, Moore JL, Franklin H, Swanson J, Liechty EA, Bose CL, Krebs NF, Michael Hambidge K, Carlo WA, Kanaiza N, Naqvi F, Pineda IS, López-Gomez W, Hamsumonde D, Harrison MS, Koso-Thomas M, Miodovnik M, Wallace DD, and McClure EM

Subjects
Adolescent, Adult, Cluster Analysis, Developing Countries, Female, Humans, Infant, Infant Mortality, Infant, Newborn, Male, Maternal Mortality, Pregnancy, Pregnancy Complications mortality, Young Adult, Maternal-Child Health Services, Medically Underserved Area, Perinatal Care, Pregnancy Complications diagnostic imaging, Ultrasonography, Prenatal
Abstract

Objective: Ultrasound is widely regarded as an important adjunct to antenatal care (ANC) to guide practice and reduce perinatal mortality. We assessed the impact of ANC ultrasound use at health centres in resource-limited countries., Design: Cluster randomised trial., Setting: Clusters within five countries (Democratic Republic of Congo, Guatemala, Kenya, Pakistan, and Zambia) METHODS: Clusters were randomised to standard ANC or standard care plus two ultrasounds and referral for complications. The study trained providers in intervention clusters to perform basic obstetric ultrasounds., Main Outcome Measures: The primary outcome was a composite of maternal mortality, maternal near-miss mortality, stillbirth, and neonatal mortality., Results: During the 24-month trial, 28 intervention and 28 control clusters had 24 263 and 23 160 births, respectively; 78% in the intervention clusters received at least one study ultrasound; 60% received two. The prevalence of conditions noted including twins, placenta previa, and abnormal lie was within expected ranges. 9% were referred for an ultrasound-diagnosed condition, and 71% attended the referral. The ANC (RR 1.0 95% CI 1.00, 1.01) and hospital delivery rates for complicated pregnancies (RR 1.03 95% CI 0.89, 1.20) did not differ between intervention and control clusters nor did the composite outcome (RR 1.09 95% CI 0.97, 1.23) or its individual components., Conclusions: Despite availability of ultrasound at ANC in the intervention clusters, neither ANC nor hospital delivery for complicated pregnancies increased. The composite outcome and the individual components were not reduced., Tweetable Abstract: Antenatal care ultrasound did not improve a composite outcome that included maternal, fetal, and neonatal mortality., (© 2018 Royal College of Obstetricians and Gynaecologists.)

Published
2018
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26. A prospective cause of death classification system for maternal deaths in low and middle-income countries: results from the Global Network Maternal Newborn Health Registry.

Author

Pasha O, McClure EM, Saleem S, Tikmani SS, Lokangaka A, Tshefu A, Bose CL, Bauserman M, Mwenechanya M, Chomba E, Carlo WA, Garces AL, Figueroa L, Hambidge KM, Krebs NF, Goudar S, Kodkany BS, Dhaded S, Derman RJ, Patel A, Hibberd PL, Esamai F, Tenge C, Liechty EA, Moore JL, Wallace DD, Koso-Thomas M, Miodovnik M, and Goldenberg RL

Subjects
Black People statistics & numerical data, Democratic Republic of the Congo epidemiology, Developing Countries, Female, Guatemala epidemiology, Humans, Income, India epidemiology, Kenya epidemiology, Maternal Death etiology, Maternal Mortality, Pakistan epidemiology, Pregnancy, Prospective Studies, Registries, White People statistics & numerical data, Zambia epidemiology, Cause of Death, Global Health statistics & numerical data, Maternal Death classification, Pregnancy Complications mortality
Abstract

Objective: To describe the causes of maternal death in a population-based cohort in six low- and middle-income countries using a standardised, hierarchical, algorithmic cause of death (COD) methodology., Design: A population-based, prospective observational study., Setting: Seven sites in six low- to middle-income countries including the Democratic Republic of the Congo (DRC), Guatemala, India (two sites), Kenya, Pakistan and Zambia., Population: All deaths among pregnant women resident in the study sites from 2014 to December 2016., Methods: For women who died, we used a standardised questionnaire to collect clinical data regarding maternal conditions present during pregnancy and delivery. These data were analysed using a computer-based algorithm to assign cause of maternal death based on the International Classification of Disease-Maternal Mortality system (trauma, termination of pregnancy-related, eclampsia, haemorrhage, pregnancy-related infection and medical conditions). We also compared the COD results to healthcare-provider-assigned maternal COD., Main Outcome Measures: Assigned causes of maternal mortality., Results: Among 158 205 women, there were 221 maternal deaths. The most common algorithm-assigned maternal COD were obstetric haemorrhage (38.6%), pregnancy-related infection (26.4%) and pre-eclampsia/eclampsia (18.2%). Agreement between algorithm-assigned COD and COD assigned by healthcare providers ranged from 75% for haemorrhage to 25% for medical causes coincident to pregnancy., Conclusions: The major maternal COD in the Global Network sites were haemorrhage, pregnancy-related infection and pre-eclampsia/eclampsia. This system could allow public health programmes in low- and middle-income countries to generate transparent and comparable data for maternal COD across time or regions., Tweetable Abstract: An algorithmic system for determining maternal cause of death in low-resource settings is described., (© 2017 Royal College of Obstetricians and Gynaecologists.)

Published
2018
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27. Global Network for Women's and Children's Health Research: probable causes of stillbirth in low- and middle-income countries using a prospectively defined classification system.

Author

McClure EM, Garces A, Saleem S, Moore JL, Bose CL, Esamai F, Goudar SS, Chomba E, Mwenechanya M, Pasha O, Tshefu A, Patel A, Dhaded SM, Tenge C, Marete I, Bauserman M, Sunder S, Kodkany BS, Carlo WA, Derman RJ, Hibberd PL, Liechty EA, Hambidge KM, Krebs NF, Koso-Thomas M, Miodovnik M, Wallace DD, and Goldenberg RL

Subjects
Africa epidemiology, Asia epidemiology, Developing Countries, Female, Global Health, Guatemala epidemiology, Humans, Maternal-Child Health Services, Pregnancy, Pregnancy Complications epidemiology, Prospective Studies, Algorithms, Registries, Stillbirth epidemiology
Abstract

Objective: We sought to classify causes of stillbirth for six low-middle-income countries using a prospectively defined algorithm., Design: Prospective, observational study., Setting: Communities in India, Pakistan, Guatemala, Democratic Republic of Congo, Zambia and Kenya., Population: Pregnant women residing in defined study regions., Methods: Basic data regarding conditions present during pregnancy and delivery were collected. Using these data, a computer-based hierarchal algorithm assigned cause of stillbirth. Causes included birth trauma, congenital anomaly, infection, asphyxia, and preterm birth, based on existing cause of death classifications and included contributing maternal conditions., Main Outcome Measures: Primary cause of stillbirth., Results: Of 109 911 women who were enrolled and delivered (99% of those screened in pregnancy), 2847 had a stillbirth (a rate of 27.2 per 1000 births). Asphyxia was the cause of 46.6% of the stillbirths, followed by infection (20.8%), congenital anomalies (8.4%) and prematurity (6.6%). Among those caused by asphyxia, 38% had prolonged or obstructed labour, 19% antepartum haemorrhage and 18% pre-eclampsia/eclampsia. About two-thirds (67.4%) of the stillbirths did not have signs of maceration., Conclusions: Our algorithm determined cause of stillbirth from basic data obtained from lay-health providers. The major cause of stillbirth was fetal asphyxia associated with prolonged or obstructed labour, pre-eclampsia and antepartum haemorrhage. In the African sites, infection also was an important contributor to stillbirth. Using this algorithm, we documented cause of stillbirth and its trends to inform public health programs, using consistency, transparency, and comparability across time or regions with minimal burden on the healthcare system., Tweetable Abstract: Major causes of stillbirth are asphyxia, pre-eclampsia and haemorrhage. Infections are important in Africa., (© 2017 Royal College of Obstetricians and Gynaecologists.)

Published
2018
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28. Documentation of smoking: role of age, gender, and ethnicity.

Author

Okuyemi KS, Harris KJ, Ahluwalia JS, and Wallace DD

Subjects
Adult, Age Distribution, Aged, Female, Humans, Logistic Models, Male, Middle Aged, Midwestern United States epidemiology, Odds Ratio, Risk Factors, Sex Distribution, Smoking ethnology, Smoking epidemiology
Abstract

This study assessed the role of age, gender, and ethnicity in chart documentation of smoking by primary care providers. Clinic patients (n = 304) were asked their smoking status and medical records were reviewed. Twenty-nine percent of reviewed patients were smokers, 27.6% former smokers, and 43.1% nonsmokers. Providers were more likely to document smoking among males (OR = 4.6; 95% CI = 2.2-9.5), middle-aged patients (OR = 4.0; 95% CI = 1.4-11.0), and smokers (OR = 8.1; 95% CI = 4.1-16.0). Data revealed selective documentation of smoking in males and middle-aged patients by providers, suggesting gender and age bias in the recognition and documentation of this risky behavior. We conclude that providers should screen for smoking in all patients regardless of age or gender.

Published
2001

29. Factors influencing infant visits to emergency departments.

Author

Sharma V, Simon SD, Bakewell JM, Ellerbeck EF, Fox MH, and Wallace DD

Subjects
Age Factors, Cohort Studies, Humans, Infant, Newborn, Medicaid statistics & numerical data, Medical Record Linkage, Medical Records, Problem-Oriented statistics & numerical data, Medicare statistics & numerical data, Missouri, Racial Groups, Registries, Retrospective Studies, Child Health Services statistics & numerical data, Emergency Service, Hospital statistics & numerical data
Abstract

Objectives: To follow the 1995 birth cohort of infants, born in the State of Missouri, through their first birthday to: 1) examine their rates of visits to emergency departments (EDs), 2) identify predictors of any ED visit, 3) examine rates of nonurgent ED visits, and 4) identify predictors of nonurgent visits., Methods: This was a retrospective population cohort study. Using deterministic linkage procedures, 2 databases at the Missouri Department of Health (DOH; (the patient abstract database and the birth registry database) were linked by DOH personnel. International Classification of Diseases, Ninth Revision-Clinical Modification codes for ED visits were classified as emergent, urgent, or nonurgent by 2 researchers. Eight newborn characteristics were chosen for analysis. Negative binomial regression was used to examine the rates and predictors of both total and nonurgent ED visits., Results: There were 935 total ED visits and 153 nonurgent ED visits per 1000 infant years. The average number of visits was.94, with 59% of infants having no visits, 21% having 1 ED visit, and 20% having 2 or more visits. Factors associated with increases in both total and nonurgent ED visits were Medicaid, self-pay, black race, rural region, presence of birth defects, and a nursery stay of >2 days. Significant interactions were found between Medicaid and race and Medicaid and rural regions on rates of ED use and nonurgent use. The highest rate of ED use, 1.8 per person year, was seen in white, rural infants on Medicaid, and the lowest rate (.4 per person year) was seen in urban white infants not on Medicaid. The highest rates of nonurgent use,.3 per person year, were among urban and rural Medicaid infants of both races and among black infants on commercial insurance. The lowest nonurgent rate,.04 per person year, was seen in white urban infants on commercial insurance., Conclusion: Infants in the State of Missouri have high rates of ED visits. Nonurgent visits are only a small portion of ED visits and cannot explain large variations in ED usage. Increased ED use by Medicaid patients may reflect continuing difficulties in accessing primary care.

Published
2000
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30. Changes in US health care access in the 90s: race and income differences from the CARDIA Study. Coronary Artery Risk Development in Young Adults.

Author

Kiefe CI, Williams OD, Weissman NW, Schreiner PJ, Sidney S, and Wallace DD

Subjects
Adolescent, Adult, Cohort Studies, Female, Financing, Personal, Health Services Accessibility economics, Health Services Accessibility statistics & numerical data, Health Services Research, Humans, Insurance Coverage, Longitudinal Studies, Male, Prospective Studies, United States, Urban Population, Black or African American statistics & numerical data, Health Services Accessibility trends, Income classification, Income statistics & numerical data, White People statistics & numerical data
Abstract

Objective: Health care financing is changing rapidly in the United States. We investigated whether and how health care access is changing concurrently with changes in financing, with special attention to a minority population., Methods: We examined a longitudinal biracial (half African-American, half White) urban cohort of 3,565 individuals, aged 25-37 years old, in 1992-93 and again in 1995-96. We measured access by self-reported (1) health insurance status, (2) regular source of medical care, and (3) lack of care due to financial problems., Results: In 1992-93, 30.3% of the cohort experienced at least one access barrier, with a decline to 26.8% in 1995-96 (P<.005). However, access improved more for Whites than for African Americans; and access improved for higher, but not for lower, income groups (7% improvement for high income, vs 2% deterioration for lower income, P<.01). In addition, there was an 11% to 19% absolute increase in individuals making co-payments for health care utilization across all race/sex groups, with African Americans having markedly higher proportions of cost-sharing. African-American, low income, and unemployed individuals reported more acute care, but fewer outpatient visits. Income and employment explained racial differences., Conclusion: While access has improved or stabilized for higher income groups, there is a widening gap according to income, accompanied by an acute care pattern for low income groups that may be both inadequate and cost inefficient.

Published
2000

31. Smoking survey at a midwestern U.S. medical center.

Author

Landeck BF 2nd, Wallace DD, and Neuberger JS

Subjects
Adult, Attitude to Health, Educational Status, Female, Health Knowledge, Attitudes, Practice, Humans, Kansas epidemiology, Male, Middle Aged, Needs Assessment, Occupations statistics & numerical data, Personnel, Hospital education, Personnel, Hospital psychology, Racial Groups, Sex Distribution, Smoking psychology, Surveys and Questionnaires, Academic Medical Centers, Personnel, Hospital statistics & numerical data, Smoking epidemiology, Tobacco Smoke Pollution statistics & numerical data
Abstract

Background: In an effort to learn more about the smoking behavior of hospital employees, a study was conducted at the University of Kansas Medical Center (KUMC) regarding tobacco usage and secondhand smoke exposure., Methods: An anonymous voluntary survey was distributed to 4177 full-time employees in Kansas City and Wichita during June and July of 1998. Questions included tobacco usage and exposure to secondhand smoke. The survey results were assimilated in a data base, which was analyzed in a variety of ways to arrive at several conclusive findings., Results: Of the 1187 respondents (28. 4%), 35.1% had smoked at least 100 cigarettes in their life (41% of those had at least a 10 pack-year history), and 11.8% currently smoked. The groups with the highest percentage of current smokers were females (12%), blacks (17%), Kansas City campus employees (12%), and nonfaculty (13%). Sixty-seven percent of respondents were exposed to secondhand smoke in the previous week, and 25% were exposed at KUMC., Conclusions: After arriving at the results of this study, recommendations include starting an educational campaign against smoking, promoting cessation programs, moving the current smoking area to a less populated area on campus, and investigating a total campus ban on smoking., (Copyright 2000 American Health Foundation and Academic Press.)

Published
2000
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32. Chemical changes in the photoreceptor outer segments due to iron induced oxidative stress: analysis by Fourier transform infrared (FT-IR) microspectroscopy.

Author

Homan JA, Radel JD, Wallace DD, Wetzel DL, and LeVine SM

Subjects
Animals, Ferrous Compounds administration & dosage, Ferrous Compounds metabolism, Injections, Iron administration & dosage, Rats, Rats, Long-Evans, Rod Cell Outer Segment ultrastructure, Sodium Chloride administration & dosage, Spectroscopy, Fourier Transform Infrared methods, Iron metabolism, Oxidative Stress, Rod Cell Outer Segment metabolism
Abstract

Oxidative stress is thought to be an important pathogenic mechanism in many diseases of the retina. The purpose of this study was to investigate the chemical changes that are present in the photoreceptor outer segments of the retina following exposure to oxidative stress. Fourier transform infrared (FT-IR) microspectroscopy enables the characterization and semi-quantitation of chemical functional groups in microscopic regions of tissue sections. This technique was used to evaluate the chemical changes in the outer segments following exposure to ferrous sulfate, which promotes oxidative tissue damage. A reduction of C=C-H and C=O functional groups was observed in the outer segments of iron-injected eyes compared to vehicle-injected eyes at 3 days following injection, which is prior to major histological changes that occur by 7 days. These functional groups are found in docosahexaenoic acid (DHA), which is present at a high concentration in the outer segments. DHA contains a series of six cis-conjugated double bonds, which are vulnerable to free radical attack, and the reduction of these unsaturation group absorptions suggests that DHA was degraded and/or removed from the outer segments. An unexpected finding was that several other chemical functional groups increased in concentration over time in the outer segments of vehicle-injected eyes compared to non-injected eyes. These increases generally did not include C=C-H or C=O, which suggests that either DHA was being degraded while other organic molecules were being concentrated, or that production of DHA failed to be upregulated in vehicle-injected eyes. In summary, there was a loss of both C=C-H and C=O functional group concentrations in the outer segments of iron-injected eyes, and there was an increased concentration of several other chemical functional groups following trauma induced by vehicle injection.

Published
2000

33. Breast cancer chemoprevention trials using the fine-needle aspiration model.

Author

Kimler BF, Fabian CJ, and Wallace DD

Subjects
Antineoplastic Agents therapeutic use, Biomarkers, Tumor analysis, Breast metabolism, Breast Neoplasms metabolism, Clinical Protocols, Clinical Trials as Topic, Eflornithine therapeutic use, ErbB Receptors metabolism, Female, Humans, Hyperplasia, Placebos, Tumor Suppressor Protein p53 metabolism, Biopsy, Needle methods, Breast pathology, Breast Neoplasms prevention & control
Abstract

Selection of surrogate endpoint biomarkers (SEBs) and appropriate study design are two of the main challenges in evaluating potential chemopreventive agents. In a prospective random fine-needle aspiration (FNA) study of women at high risk of development of breast cancer, we previously demonstrated that cytologic evidence of epithelial hyperplasia with or without atypia, as well as abnormalities of several cellular biomarkers (DNA ploidy; immunocytochemical expression of p53, EGFR, ER, and/or Her-2/neu), were more prevalent in high-risk women than in low-risk controls. We also demonstrated that the subsequent development of breast cancer was best predicted by an initial presentation of hyperplasia with atypia, as well as by multiple biomarker abnormalities. These findings indicate that FNA cytology and biomarkers can be used to identify women who are appropriate subjects for chemoprevention trials, and can then be used as surrogate endpoint biomarkers to monitor efficacy of potential agents. An example of this use in an ongoing single-agent phase II trial is provided. Several options for study design of possible multi-agent breast cancer chemoprevention trials are discussed, depending upon the existing preclinical and clinical data, the questions being asked, and the number of eligible subjects available.

Published
2000

34. Comparison of long-term renal function after spinal cord injury using different urinary management methods.

Author

Sekar P, Wallace DD, Waites KB, DeVivo MJ, Lloyd LK, Stover SL, and Dubovsky EV

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Cystostomy, Female, Humans, Infant, Linear Models, Long-Term Care, Male, Middle Aged, Physical Stimulation methods, Time Factors, Urinary Bladder, Neurogenic etiology, Urinary Catheterization methods, Urinary Diversion, Renal Plasma Flow, Effective, Spinal Cord Injuries complications, Urinary Bladder, Neurogenic physiopathology, Urinary Bladder, Neurogenic rehabilitation
Abstract

Objective: To determine the effect of different bladder management methods on long-term renal function in persons with spinal cord injury (SCI)., Design: Cohort study., Setting: Model SCI care system within a large teaching hospital., Patients: Consecutive sample of 1,114 persons with SCI who were injured between 1969 and 1994., Main Outcome Measure: Total and individual kidney effective renal plasma flow (ERPF)., Results: ERPF was generally lower in persons with cervical injuries or kidneys that had a renal stone, older persons, and women. Overall, there was very little change in renal function as time postinjury increased, and there were no clinically meaningful differences in the change in renal function over time among persons using different bladder management methods., Conclusion: Renal function was adequately preserved in the great majority of persons and did not appear to be influenced to any great extent by method of bladder management.

Published
1997
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35. Discrepancies between centric occlusion and centric relation in orthodontically treated patients.

Author

Gaither EL, Sadowsky PL, Vlachos CC, and Wallace DD

Subjects
Adolescent, Child, Female, Humans, Jaw Relation Record, Male, Observer Variation, Orthodontic Appliances, Outcome Assessment, Health Care, Patient Care Planning, Recurrence, Reproducibility of Results, Time Factors, Centric Relation, Dental Occlusion, Centric, Malocclusion therapy, Orthodontics, Corrective
Abstract

Condylar position between centric occlusion (CO) and centric relation (CR) was compared for 24 adolescent orthodontic patients at pretreatment, posttreatment, and during the retention phase of orthodontic treatment. Models were mounted using a face-bow transfer and CR interocclusal registrations. Differences in CO-CR were then measured at the condylar level in the x, y, and z dimensions. The data were analyzed statistically to determine the mean CO-CR differences in the sample as well as the magnitude and direction of the CO-CR differences from one time period to the next. Results showed that the mean three-dimensional distance between CO and CR tended to increase from pretreatment to the retention phase for the right and left sides, the left side showing a greater increase. Intraexaminer variability accounted for 20% to 25% of the total variability when all possible sources of variability were considered. Correlation with a second examiner in recording CR was in the range of .61 and .75 for the right and left sides, respectively. Interexaminer variability was found to be similar to the variability associated with the CO-CR discrepancies over time. Consequently, the differences in measurements obtained could be the result of changes in the CO-CR relationship, examiner variability, or a combination of both.

Published
1997

36. A three-dimensional analysis of mandibular arch changes following curve of Spee leveling in nonextraction orthodontic treatment.

Author

Chung TS, Sadowsky PL, Wallace DD, and McCutcheon MJ

Subjects
Computer Graphics, Female, Humans, Image Processing, Computer-Assisted, Linear Models, Male, Malocclusion pathology, Malocclusion therapy, Models, Dental statistics & numerical data, Transducers, Dental Arch anatomy & histology, Dental Occlusion, Mandible anatomy & histology, Orthodontics statistics & numerical data
Abstract

The present study was conducted to determine the effects of curve of Spee leveling on three-dimensional arch length and specific components of arch form. The mandibular pretreatment and posttreatment dental casts of 33 patients treated orthodontically without the extraction of teeth were digitized with a three-dimensional positioning transducer integrated with a graphics calculator. Statistical analysis was carried out with general linear models and the calculation of Pearson correlation coefficients of the relationships between the dependent variable of the curve of Spee leveling and the independent variables of arch length, arch depth, and three arch widths. The regression and correlation analyses essentially showed no relationship between the independent variables (arch length, arch depth, and the three arch widths) and the dependent variable (curve of Spee leveling). Although the three-dimensional arch length was increased after leveling of the curve of Spee in 24 of the 33 dental casts evaluated, the results from the statistical analyses indicated that this increased arch length was not necessarily the result of the curve of Spee leveling but may have been caused by other variables.

Published
1997

37. Do waste incinerators induce adverse respiratory effects? An air quality and epidemiological study of six communities.

Author

Shy CM, Degnan D, Fox DL, Mukerjee S, Hazucha MJ, Boehlecke BA, Rothenbacher D, Briggs PM, Devlin RB, and Wallace DD

Subjects
Adolescent, Adult, Aged, Child, Humans, Longitudinal Studies, Lung physiology, Middle Aged, Zinc adverse effects, Air Pollutants adverse effects, Hazardous Substances adverse effects, Incineration, Lung drug effects, Lung Diseases chemically induced
Abstract

The purpose of the study presented here was to simultaneously measure air quality and respiratory function and symptoms in populations living in the neighborhood of waste incinerators and to estimate the contribution of incinerator emissions to the particulate air mass in these neighborhoods. We studied the residents of three communities having, respectively, a biomedical and a municipal incinerator, and a liquid hazardous waste-burning industrial furnace. We compared results with three matched-comparison communities. We did not detect differences in concentrations of particulate matter among any of the three pairs of study communities. Average fine particulate (PM2.5) concentrations measured for 35 days varied across study communities from 16 to 32 micrograms/m3. Within the same community, daily concentrations of fine particulates varied by as much as eightfold, from 10 to 80 micrograms/m3, and were nearly identical within each pair of communities. Direct measurements of air quality and estimates based on a chemical mass balance receptor model showed that incinerator emissions did not have a major or even a modest impact on routinely monitored air pollutants. A onetime baseline descriptive survey (n = 6963) did not reveal consistent community differences in the prevalence of chronic or acute respiratory symptoms between incinerator and comparison communities, nor did we see a difference in baseline lung function tests or in the average peak expiratory flow rate measured over a period of 35 days. Based on this analysis of the first year of our study, we conclude that we have no evidence to reject the null hypothesis of no acute or chronic respiratory effects associated with residence in any of the three incinerator communities.

Published
1995
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39. Gynecology.

Author

WALLACE DD

Subjects
Progesterone analogs & derivatives, Gynecology
Published
1960

42. Gynecology.

Author

WALLACE DD

Subjects
Humans, Gynecology
Published
1958

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