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1. Patient Perspectives on Performance of a Smartphone App for Atrial FibrillationSelf-Management

Author: Mihas P, Rosman L, Armbruster T, Walker J, Deyo Z, and Gehi A
Subjects: atrial fibrillation, digital health, app, qualitative, focus group, Medicine (General), R5-920
Abstract: Paul Mihas,1 Lindsey Rosman,2 Tiffany Armbruster,2 Jennifer Walker,2 Zack Deyo,3,4 Anil Gehi2 1Odum Institute for Research in Social Science, University of North Carolina, Chapel Hill, NC, USA; 2Division of Cardiology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA; 3UNC Medical Center, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA; 4UNC Eshelman School of Pharmacy, PACE Division,University of North Carolina, Chapel Hill, NC, USACorrespondence: Paul Mihas, Email Paul_Mihas@unc.eduIntroduction: AF self-care requires patients to perform daily self-monitoring for symptoms, practice decision making to address symptom changes, and adhere to prescribed medication, diet, physical activity, and follow-up care. Technology can facilitate these critical self-care behaviors and ultimately improve patient outcomes. We assessed atrial fibrillation (AF) patients’ experiences with a smartphone application (app) for AF self-management.Methods: A focus group with 9 AF patients and app users was conducted and analyzed using qualitative research methods. The focus group was recorded, transcribed, and coded using a priori and inductive coding strategies. Participant responses for each code were synthesized to identify primary themes.Results: We identified four superordinate themes from patients’ experiences: (1) disconnect between tool and its intended use; (2) app as acknowledged tool for adherence; (3) knowledge as empowerment; (3) motives: self-interest vs supporting research. Results from this qualitative study underscore the need to clarify the app’s intended use and to better accommodate patients with different AF experiences. The disconnect between a tool and its intended use can generate frustration for users.Discussion: The study reinforces that participants not only see how the app is a tool for adherence; they also see knowledge they gain via the app as empowering, suggesting a correlation between app use and self-efficacy.Keywords: atrial fibrillation, digital health, app, qualitative, focus group
Published: 2022

2. A Systematic Review of Muscle Synergies during a Walking Gait to Define Optimal Donor-Recipient Pairings for Lower Extremity Functional Reconstruction

Author: Walker J. Magrath, BS, Cecil S. Qiu, MD, Philip J. Hanwright, MD, Sami H. Tuffaha, MD, and Nima Khavanin, MD
Subjects: Surgery, RD1-811
Abstract: Background:. Functional lower extremity reconstruction primarily aims to restore independent ambulation. We sought to define the synergies recruited during a walking gait to inform donor selection for various motor deficits. With these findings, we discuss the functional neuromuscular components of independent gait with the goal of informing lower extremity reconstruction. Methods:. A systematic review was performed using MEDLINE for articles published between January 2000 and December 2020. Search terms included (1) “motor module(s),” “synergy,” “motor pattern,” or “motor primitive” and (2) “gait,” “walking,” “ambulation,” or “locomotion.” Abstracts/full texts were reviewed by two independent reviewers. Results:. A total of 38 studies were selected. The average reported number of synergies and variance accounted for was 4.5 ± 0.9 and 88.6% ± 7.7%, respectively. Four motor modules were conserved across nearly all studies. Conclusions:. Walking can be reduced to the sequential activation of four motor modules. Activities during the stance phase are critical for both standing stability and forward progression and should be prioritized for reconstruction with the goal of preserving efficient gait. Muscles recruited during swing, except those used for ankle dorsiflexion, are less prone to injury and benefit from greater redundancy, less often necessitating reconstruction. With the emphasis on stability during stance, several synergistic or sometimes even antagonistic tendons can be used to replace their counterparts and restore efficient, independent ambulation. With a finite supply of donor tissues, and in the absence of well-defined clinical outcomes data, this research allows us to effectively prioritize reconstructive goals and maximize patient outcomes.
Published: 2022
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3. A Molecular Epidemiological Analysis Of Programmed Cell Death Ligand-1 (PD-L1) Protein Expression, Mutations And Survival In Non-Small Cell Lung Cancer

Author: Schabath MB, Dalvi TB, Dai HA, Crim AL, Midha A, Shire N, Gimbrone NT, Walker J, Greenawalt DM, Lawrence D, Rigas JR, Brody R, Potter D, Kumar NS, Huntsman SA, and Gray JE
Subjects: non-small cell lung cancer, patient outcomes, tumor mutational burden, prognostic biomarker, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Matthew B Schabath,1,2 Tapashi B Dalvi,3 Hongyue A Dai,4 Alan L Crim,4 Anita Midha,5 Norah Shire,3 Nicholas T Gimbrone,1 Jill Walker,6 Danielle M Greenawalt,7 David Lawrence,8 James R Rigas,9 Robert Brody,9 Danielle Potter,9 Naveen S Kumar,4 Shane A Huntsman,4 Jhanelle E Gray2 1Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA; 2Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA; 3Oncology R&D, AstraZeneca, Gaithersburg, MD, USA; 4M2Gen, Tampa, FL, USA; 5Department of Personalised Healthcare and Biomarkers, AstraZeneca, Cambridge, UK; 6Department of Precision Medicine Oncology, AstraZeneca, Cambridge, UK; 7Department of iMED Oncology Informatics, AstraZeneca, Waltham, MA, USA; 8Department of Global Medicines Development, AstraZeneca, Cambridge, UK; 9Department of Global Medical Affairs Oncology, AstraZeneca, Gaithersburg, MD, USACorrespondence: Matthew B SchabathH. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USATel +1 813 745 4150Fax +1 813 745 6525Email matthew.schabath@moffitt.orgPurpose: To characterize programmed cell death ligand-1 (PD-L1) expression in relation to survival and gene mutation status in patients with advanced NSCLC. The study also explored the influence of tumor mutational burden (TMB) on PD-L1 expression and patient characteristics.Patients and methods: Adult patients with histologically or cytologically documented Stage IIIB/Stage IV/recurrent/progressive NSCLC, Eastern Cooperative Oncology Group performance status 0 to 3, and >2 lines of prior systemic treatment regimens were included in this retrospective analysis. Patients were treated from 1997 to 2015 at H. Lee Moffitt Cancer Center and Research Institute, Tampa, or at 7 community centers across the United States. PD-L1 expression level was determined using the VENTANA PD-L1 (SP263) Assay. EGFR and KRAS mutation status and ALK rearrangements were determined by targeted DNA sequencing; these were obtained from clinical records where targeted DNA sequencing was not performed. TMB was calculated as the total number of somatic mutations per sample.Results: From a total of 136 patients included in the study, 23.5% had tumors with high PD-L1 expression (≥25%). There were no significant differences in patient characteristics, overall survival (OS), and progression-free survival (PFS) between patients with high PD-L1 expression (median OS: 39.5 months; median PFS: 15.8 months) vs low PD-L1 expression (
Published: 2019

4. Retrospective study of cardiovascular disease risk factors among a cohort of combat veterans with lower limb amputation

Author: Bhatnagar V, Richard E, Melcer T, Walker J, and Galarneau M
Subjects: limb amputation, combat injury, blood pressure, cardiovascular disease, dyslipidemia, insulin resistance, Expeditionary Medical Encounter Database, metabolic syndrome, posttraumatic stress disorder, Department of Veterans Affairs, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Vibha Bhatnagar,1,2 Erin Richard,1,2 Ted Melcer,3 Jay Walker,4 Michael Galarneau3 1Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA, USA; 2US Department of Veterans Affairs, San Diego Healthcare System, San Diego, CA, USA; 3Medical Modeling, Simulation and Mission Support Department, Naval Health Research Center, San Diego, CA, USA; 4Leidos, San Diego, CA, USACorrespondence: Vibha BhatnagarDepartment of Family and Preventive Medicine, University of California San Diego 9500 Gilman Drive, MC 0725, La Jolla, CA 92093, USATel +1 858 822 1233Fax +1 858 534 4642Email vbhatnag@ucsd.eduIntroduction: Previous studies have shown that veterans with lower limb amputation have a higher risk for cardiovascular disease (CVD) compared with population-based controls. American veterans who have served in Iraq and Afghanistan with lower limb amputation may be at a similarly higher risk.Patients and methods: The Navel Health Research Center (NHRC) maintains the Expeditionary Medical Encounter Database (EMED) of military personnel who have sustained combat limb amputation or serious limb injury during the conflicts in Iraq and Afghanistan. Department of Veterans Affairs data from 2003 to April 2015 was used to analyze CVD risk factors in this cohort. Veterans with either unilateral (n=442) or bilateral (n=146) lower limb amputation were compared to those with serious lower limb trauma without amputation (n=184). Multivariate regression was used to measure associations between lower limb amputation and CVD risk factors over an average of 8 years of follow-up. Outcomes included mean arterial pressure (MAP), low-density lipoprotein, high-density lipoprotein (HDL), and serum triglycerides (TG).Results: Compared with the limb injury group, those with unilateral lower limb amputation had significantly lower HDL (p
Published: 2019

5. Steroid-sparing effects and acceptability of a new skin gel containing the anti-inflammatory medicinal substance-nicotinamide

Author: Djokic-Gallagher J, Rosher P, Hart V, and Walker J
Subjects: nicotinamide, emollient, efficacy, Adex, gel, study, Dermatology, RL1-803
Abstract: Jasmina Djokic-Gallagher, Phil Rosher, Valerie Hart, Jennine WalkerResearch and Development, Dermal Laboratories Ltd, Hitchin, SG4 7QR, UKBackground/aim: Adex gel (DENI) is a leave-on emollient, containing an ancillary anti-inflammatory medicinal substance, nicotinamide, for use in the treatment and management of dry skin conditions prone to inflammation. The aim of the study was to obtain patients’ and a Medical Investigator’s feedback on the clinical performance and acceptability of the product, and to assess the product’s potential for reducing patients’ reliance on topical corticosteroids and immunomodulators.Methods: Forty-eight patients were enrolled with 43 patients completing the study. These patients used the product on its own, or as adjunctive therapy, for two weeks instead of their usual emollient, applying it three times daily or more often if necessary. Using a questionnaire, subjects then indicated whether they were in agreement or not with various statements about the clinical performance and acceptability of the product. In the second part of the study, twenty patients used the product for four weeks, this time using it as often as they liked. The Medical Investigator looked at both the performance and the acceptability of the treatment. Patients completed a questionnaire again to indicate how they used it and whether their use of topical corticosteroids and/or immunomodulator treatments had changed.Results: Patient’s responses were very positive, ranging from 81% to 100% agreement with each performance statement in relation to beneficial effects on the skin. The Medical Investigator considered that for nearly all patients, DENI gel was a helpful and convenient addition to their treatment regime. When questioned on steroid-sparing effects, more than half reported that they needed to use less of their other anti-inflammatory treatments, and nearly 95% reported that they felt their skin condition had benefited from using DENI gel.Conclusion: This new anti-inflammatory emollient appears to be a helpful addition to the treatment armamentarium for eczema and psoriasis that may reduce reliance on topical corticosteroids and immunomodulators.Keywords: nicotinamide, emollient, steroid sparing effect, evidence
Published: 2019

6. High-fidelity and Fault-tolerant Teleportation of a Logical Qubit using Transversal Gates and Lattice Surgery on a Trapped-ion Quantum Computer

Author: Ryan-Anderson, C., Brown, N. C., Baldwin, C. H., Dreiling, J. M., Foltz, C., Gaebler, J. P., Gatterman, T. M., Hewitt, N., Holliman, C., Horst, C. V., Johansen, J., Lucchetti, D., Mengle, T., Matheny, M., Matsuoka, Y., Mayer, K., Mills, M., Moses, S. A., Neyenhuis, B., Pino, J., Siegfried, P., Stutz, R. P., Walker, J., and Hayes, D.
Subjects: Quantum Physics
Abstract: Quantum state teleportation is commonly used in designs for large-scale fault-tolerant quantum computers. Using Quantinuum's H2 trapped-ion quantum processor, we implement the first demonstration of a fault-tolerant state teleportation circuit for a quantum error correction code - in particular, the planar topological [[7,1,3]] color code, or Steane code. The circuits use up to 30 trapped ions at the physical layer qubits and employ real-time quantum error correction - decoding mid-circuit measurement of syndromes and implementing corrections during the protocol. We conduct experiments on several variations of logical teleportation circuits using both transversal gates and lattice surgery protocols. Among the many measurements we report on, we measure the logical process fidelity of the transversal teleportation circuit to be 0.975(2) and the logical process fidelity of the lattice surgery teleportation circuit to be 0.851(9). Additionally, we run a teleportation circuit that is equivalent to Knill-style quantum error correction and measure the process fidelity to be 0.989(2).
Published: 2024

7. Solar neutrino measurements using the full data period of Super-Kamiokande-IV

Author: Collaboration, Super-Kamiokande, Abe, K., Bronner, C., Hayato, Y., Hiraide, K., Hosokawa, K., Ieki, K., Ikeda, M., Imaizumi, S., Iyogi, K., Kameda, J., Kanemura, Y., Kaneshima, R., Kashiwagi, Y., Kataoka, Y., Kato, Y., Kishimoto, Y., Miki, S., Mine, S., Miura, M., Mochizuki, T., Moriyama, S., Nagao, Y., Nakahata, M., Nakano, Y., Nakayama, S., Noguchi, Y., Okada, T., Okamoto, K., Orii, A., Sato, K., Sekiya, H., Shiba, H., Shimizu, K., Shiozawa, M., Sonoda, Y., Suzuki, Y., Takeda, A., Takemoto, Y., Takenaka, A., Tanaka, H., Watanabe, S., Yano, T., Han, S., Kajita, T., Okumura, K., Tashiro, T., Tomiya, T., Wang, R., Wang, X., Yoshida, S., Bravo-Berguno, D., Fernandez, P., Labarga, L., Ospina, N., Zaldivar, B., Pointon, B. W., Blaszczyk, F. d. M., Kachulis, C., Kearns, E., Raaf, J. L., Stone, J. L., Wan, L., Wester, T., Bian, J., Griskevich, N. J., Kropp, W. R., Locke, S., Smy, M. B., Sobel, H. W., Takhistov, V., Weatherly, P., Yankelevich, A., Ganezer, K. S., Hill, J., Jang, M. C., Kim, J. Y., Lee, S., Lim, I. T., Moon, D. H., Park, R. G., Bodur, B., Scholberg, K., Walter, C. W., Beauchene, A., Bernard, L., Coffani, A., Drapier, O., Hedri, S. El, Giampaolo, A., Imber, J., Mueller, Th. A., Paganini, P., Rogly, R., Quilain, B., Santos, A., Nakamura, T., Jang, J. S., Machado, L. N., Learned, J. G., Matsuno, S., Iovine, N., Choi, K., Cao, S., Anthony, L. H. V., Litchfield, R. P., Prouse, N., Marin, D., Scott, M., Sztuc, A. A., Uchida, Y., Berardi, V., Catanesi, M. G., Intonti, R. A., Radicioni, E., Calabria, N. F., De Rosa, G., Langella, A., Collazuol, G., Iacob, F., Lamoureux, M., Mattiazzi, M., Ludovici, L., Gonin, M., Perisse, L., Pronost, G., Fujisawa, C., Maekawa, Y., Nishimura, Y., Okazaki, R., Friend, M., Hasegawa, T., Ishida, T., Jakkapu, M., Kobayashi, T., Matsubara, T., Nakadaira, T., Nakamura, K., Oyama, Y., Sakashita, K., Sekiguchi, T., Tsukamoto, T., Boschi, T., Bhuiyan, N., Burton, G. T., Gao, J., Goldsack, A., Katori, T., Di Lodovico, F., Migenda, J., Sedgwick, S. Molina, Ramsden, R. M., Taani, M., Xie, Z., Zsoldos, S., Abe, KE., Hasegawa, M., Isobe, Y., Kotsar, Y., Miyabe, H., Ozaki, H., Shiozawa, T., Sugimoto, T., Suzuki, A. T., Takagi, Y., Takeuchi, Y., Yamamoto, S., Zhong, H., Ashida, Y., Feng, J., Feng, L., Hayashino, T., Hirota, S., Hu, J. R., Hu, Z., Jiang, M., Kawaue, M., Kikawa, T., Mori, M., Nakamura, KE., Nakaya, T., Wendell, R. A., Yasutome, K., Jenkins, S. J., McCauley, N., Mehta, P., Pritchard, A., Tarrant, A., Wilking, M. J., Fukuda, Y., Itow, Y., Menjo, H., Murase, M., Ninomiya, K., Niwa, T., Tsukada, M., Yoshioka, Y., Frankiewicz, K., Lagoda, J., Mandal, M., Mijakowski, P., Prabhu, Y. S., Zalipska, J., Jiang, J., Jia, M., Jung, C. K., Palomino, J. L., Santucci, G., Shi, W., Vilela, C., Yanagisawa, C., Fukuda, D., Hagiwara, K., Harada, M., Hino, Y., Horai, T., Ishino, H., Ito, S., Kitagawa, H., Koshio, Y., Ma, W., Nakanishi, F., Piplani, N., Sakai, S., Sakuda, M., Tada, T., Tano, T., Xu, C., Yamaguchi, R., Ishizuka, T., Kuno, Y., Barr, G., Barrow, D., Cook, L., Samani, S., Simpson, C., Wark, D., Holin, A. M., Nova, F., Jung, S., Yang, B., Yang, J. Y., Yoo, J., Fannon, J. E. P., Kneale, L., Malek, M., McElwee, J. M., Stone, O., Thiesse, M. D., Thompson, L. F., Wilson, S. T., Okazawa, H., Lakshmi, S. M., Choi, Y., Kim, S. B., Kwon, E., Seo, J. W., Yu, I., Ichikawa, A. K., Tairahune, S., Nishijima, K., Eguchi, A., Iwamoto, K., Nakagiri, K., Nakajima, Y., Ogawa, N., Shima, S., Watanabe, E., Yokoyama, M., Calland, R. G., Fujita, S., Jesus-Valls, C., Junjie, X., Ming, T. K., de Perio, P., Martens, K., Murdoch, M., Vagins, M. R., Izumiyama, S., Kuze, M., Matsumoto, R., Okajima, Y., Tanaka, M., Yoshida, T., Inomoto, M., Ishitsuka, M., Ito, H., Kinoshita, T., Ohta, K., Ommura, Y., Shinoki, M., Shigeta, N., Suganuma, T., Yamaguchi, K., Martin, J. F., Nantais, C. M., Tanaka, H. A., Towstego, T., Gaur, R., Gousy-Leblanc, V., Hartz, M., Konaka, A., Li, X., Chen, S., Xu, B. D., Zhang, B., Berkman, S., Posiadala-Zezula, M., Boyd, S. B., Edwards, R., Hadley, D., Nicholson, M., O'Flaherty, M., Richards, B., Ali, A., Jamieson, B., Walker, J., Amanai, S., Marti, Ll., Minamino, A., Pintaudi, G., Sano, S., Sasaki, R., Suzuki, S., and Wada, K.
Subjects: High Energy Physics - Experiment
Abstract: An analysis of solar neutrino data from the fourth phase of Super-Kamiokande~(SK-IV) from October 2008 to May 2018 is performed and the results are presented. The observation time of the data set of SK-IV corresponds to $2970$~days and the total live time for all four phases is $5805$~days. For more precise solar neutrino measurements, several improvements are applied in this analysis: lowering the data acquisition threshold in May 2015, further reduction of the spallation background using neutron clustering events, precise energy reconstruction considering the time variation of the PMT gain. The observed number of solar neutrino events in $3.49$--$19.49$ MeV electron kinetic energy region during SK-IV is $65,443^{+390}_{-388}\,(\mathrm{stat.})\pm 925\,(\mathrm{syst.})$ events. Corresponding $\mathrm{^{8}B}$ solar neutrino flux is $(2.314 \pm 0.014\, \rm{(stat.)} \pm 0.040 \, \rm{(syst.)}) \times 10^{6}~\mathrm{cm^{-2}\,s^{-1}}$, assuming a pure electron-neutrino flavor component without neutrino oscillations. The flux combined with all SK phases up to SK-IV is $(2.336 \pm 0.011\, \rm{(stat.)} \pm 0.043 \, \rm{(syst.)}) \times 10^{6}~\mathrm{cm^{-2}\,s^{-1}}$. Based on the neutrino oscillation analysis from all solar experiments, including the SK $5805$~days data set, the best-fit neutrino oscillation parameters are $\rm{sin^{2} \theta_{12,\,solar}} = 0.306 \pm 0.013 $ and $\Delta m^{2}_{21,\,\mathrm{solar}} = (6.10^{+ 0.95}_{-0.81}) \times 10^{-5}~\rm{eV}^{2}$, with a deviation of about 1.5$\sigma$ from the $\Delta m^{2}_{21}$ parameter obtained by KamLAND. The best-fit neutrino oscillation parameters obtained from all solar experiments and KamLAND are $\sin^{2} \theta_{12,\,\mathrm{global}} = 0.307 \pm 0.012 $ and $\Delta m^{2}_{21,\,\mathrm{global}} = (7.50^{+ 0.19}_{-0.18}) \times 10^{-5}~\rm{eV}^{2}$., Comment: 47 pages, 61 figures
Published: 2023
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8. Longitudinal Study of Georgia's Pre-K Program. Final Report: Pre-K through 4th Grade

Author: University of North Carolina at Chapel Hill, FPG Child Development Institute, Soliday Hong, S., Zadrozny, S., Walker, J., Love, E. N. G., Osborne, J. D., Owen, J. L., and Peinser-Feinberg, E.
Abstract: The purpose of this evaluation study was to examine children's longitudinal academic and social outcomes associated with attendance in Georgia's Pre-K Program and to examine the quality of the classrooms attended. This report covers pre-k to 4th grade outcomes collected between the 2013-2014 and 2018-2019 school years as well as a sub-study comparing 3rd and 4th grade outcomes of children who attended Georgia's Pre-K Program with children who did not attend any pre-k program. The primary evaluation questions include: (1) What are the longitudinal outcomes through 4th grade for children who attended Georgia's Pre-K Program?; (2) What factors predict better longitudinal outcomes for children?; (3) What is the quality of children's instructional experiences from pre-k through 4th grade?; and (4) Are there differential long-term outcomes for children with and without Georgia's Pre-K experience? [For the summary report, see ED630838.]
Published: 2023

9. Longitudinal Study of Georgia's Pre-K Program: Pre-K through 4th Grade

Author: University of North Carolina at Chapel Hill, FPG Child Development Institute, Soliday Hong, S., Zadrozny, S., Walker, J., Love, E. N. G., Osborne, J. D., Owen, J. L., and Peisner-Feinberg, E.
Abstract: Georgia's Pre-K Longitudinal Study followed a statewide sample of 1,169 children who attended Georgia's Pre-K Program in 2013-14 through their 4th grade year in 2018-19. The study was conducted by researchers at the Frank Porter Graham (FPG) Child Development Institute at the University of North Carolina at Chapel Hill. The following summary describes the design and results of the full study. [For the full report, see ED630837.]
Published: 2023

10. Balancing Community and Research Needs in Gender Measurement Decisions

Author: Herman, Ryan, Cavic, Elizabeth, Puckett, Jae A., Ran, Davy, Galupo, M. Paz, Garrett-Walker, J, and Veldhuis, Cindy B.
Published: 2024
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11. Spontaneously sliding multipole spin density waves in cold atoms

Author: Labeyrie, G., Walker, J. G. M., Robb, G. R. M., Kaiser, R., and Ackemann, T.
Subjects: Quantum Physics, Condensed Matter - Statistical Mechanics, Nonlinear Sciences - Pattern Formation and Solitons
Abstract: We report on the observation of spontaneously drifting coupled spin and quadrupolar density waves in the ground state of laser driven Rubidium atoms. These laser-cooled atomic ensembles exhibit spontaneous magnetism via light mediated interactions when submitted to optical feedback by a retro-reflecting mirror. Drift direction and chirality of the waves arise from spontaneous symmetry breaking. The observations demonstrate a novel transport process in out-of-equilibrium magnetic systems.
Published: 2023

12. A Race Track Trapped-Ion Quantum Processor

Author: Moses, S. A., Baldwin, C. H., Allman, M. S., Ancona, R., Ascarrunz, L., Barnes, C., Bartolotta, J., Bjork, B., Blanchard, P., Bohn, M., Bohnet, J. G., Brown, N. C., Burdick, N. Q., Burton, W. C., Campbell, S. L., Campora III, J. P., Carron, C., Chambers, J., Chan, J. W., Chen, Y. H., Chernoguzov, A., Chertkov, E., Colina, J., Curtis, J. P., Daniel, R., DeCross, M., Deen, D., Delaney, C., Dreiling, J. M., Ertsgaard, C. T., Esposito, J., Estey, B., Fabrikant, M., Figgatt, C., Foltz, C., Foss-Feig, M., Francois, D., Gaebler, J. P., Gatterman, T. M., Gilbreth, C. N., Giles, J., Glynn, E., Hall, A., Hankin, A. M., Hansen, A., Hayes, D., Higashi, B., Hoffman, I. M., Horning, B., Hout, J. J., Jacobs, R., Johansen, J., Jones, L., Karcz, J., Klein, T., Lauria, P., Lee, P., Liefer, D., Lytle, C., Lu, S. T., Lucchetti, D., Malm, A., Matheny, M., Mathewson, B., Mayer, K., Miller, D. B., Mills, M., Neyenhuis, B., Nugent, L., Olson, S., Parks, J., Price, G. N., Price, Z., Pugh, M., Ransford, A., Reed, A. P., Roman, C., Rowe, M., Ryan-Anderson, C., Sanders, S., Sedlacek, J., Shevchuk, P., Siegfried, P., Skripka, T., Spaun, B., Sprenkle, R. T., Stutz, R. P., Swallows, M., Tobey, R. I., Tran, A., Tran, T., Vogt, E., Volin, C., Walker, J., Zolot, A. M., and Pino, J. M.
Subjects: Quantum Physics
Abstract: We describe and benchmark a new quantum charge-coupled device (QCCD) trapped-ion quantum computer based on a linear trap with periodic boundary conditions, which resembles a race track. The new system successfully incorporates several technologies crucial to future scalability, including electrode broadcasting, multi-layer RF routing, and magneto-optical trap (MOT) loading, while maintaining, and in some cases exceeding, the gate fidelities of previous QCCD systems. The system is initially operated with 32 qubits, but future upgrades will allow for more. We benchmark the performance of primitive operations, including an average state preparation and measurement error of 1.6(1)$\times 10^{-3}$, an average single-qubit gate infidelity of $2.5(3)\times 10^{-5}$, and an average two-qubit gate infidelity of $1.84(5)\times 10^{-3}$. The system-level performance of the quantum processor is assessed with mirror benchmarking, linear cross-entropy benchmarking, a quantum volume measurement of $\mathrm{QV}=2^{16}$, and the creation of 32-qubit entanglement in a GHZ state. We also tested application benchmarks including Hamiltonian simulation, QAOA, error correction on a repetition code, and dynamics simulations using qubit reuse. We also discuss future upgrades to the new system aimed at adding more qubits and capabilities., Comment: 24 pages, 24 figures. Made some minor edits and added several more authors
Published: 2023
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13. The impact of gastroesophageal reflux disease and its treatment on interstitial lung disease outcomes

Author: Quinlivan, A., Neuen, D., Hansen, D., Stevens, W., Ross, L., Ferdowsi, N., Proudman, S. M., Walker, J. G., Sahhar, J., Ngian, G-S., Apostolopoulos, D., Host, L. V., Major, G., Basnayake, C., Morrisroe, K., and Nikpour, M.
Published: 2024
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14. Animal movement on the hoof and on the cart and its implications for understanding exchange within the Indus Civilisation

Author: Petrie, C. A., Lightfoot, E., Jones, P. J., Walker, J. R., Valentine, B. T., Krigbaum, J., le Roux, P., Joglekar, P. P., Shinde, V., Singh, R. N., and O’Connell, T. C.
Published: 2024
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15. The effect of transdermal opioid use on breakthrough opioid and sedative prescribing for rural patients with chronic pain in Northwest Tasmania: a longitudinal study

Author: Henshaw J, Walker J, and Geraghty D
Subjects: Medicine (General), R5-920
Abstract: John Henshaw,1 Judi Walker,2 Dom Geraghty3 1Rural Clinical School, University of Tasmania, Hobart, TAS, 2School of Rural Health, Monash University, Melbourne, VIC, 3School of Human Life Sciences, University of Tasmania, Hobart, TAS, Australia Purpose: The aim of the study reported here was to determine the frequency of prescribing of immediate-release (IR) opioids, and benzodiazepines, with both oral sustained-release (SR) and transdermal (TD) opioid maintenance treatment, in a rural population with chronic non-cancer pain (CNCP). Subjects and methods: A longitudinal study measuring IR opioid and benzodiazepine dispensed prescriptions (scripts) by route of maintenance opioid administration over time (monthly for 1 year). Subjects were opioid-treated CNCP patients from Northwest Tasmania. The outcome measures of mean monthly scripts were analyzed using generalized estimating equations with robust standard errors. Results: Details of 12,191 dispensed scripts were obtained from 140 subjects over 12 months. Mean monthly IR scripts with oral SR opioid maintenance were 0.21 (95% confidence interval [CI] 0.10; 0.32). With TD opioid maintenance, this was nonsignificantly lower (P = 0.06) at 0.04 (95% CI 0.00; 0.15). Mean monthly benzodiazepine scripts with oral SR opioids were 0.47 (95% CI 0.32; 0.62), and unchanged (P = 0.84) for TD opioids at 0.45 (95% CI 0.28; 0.62). Conclusion: There was a nonsignificant trend toward reduced prescribing of IR opioids with TD opioid-maintained, compared with oral SR opioid-maintained, CNCP rural patients. Benzodiazepine prescribing was similar for both groups. The rationale for use and the provision of breakthrough opioid analgesia for CNCP patients are complex, both for patients and their prescribers, while the regular use of benzodiazepines compounds the sedation from the subjects' maintenance opioid. The prolonged analgesic affect of TD opioids may benefit rural and remote CNCP populations and reduce the risk of diversion associated with oral opioids. Keywords: benzodiazepines, rural health, drug diversion, chronic non-cancer pain
Published: 2013

16. Solving Ax=b

Author: Walker, J. Douglas, primary and McLean, Noah M., additional
Published: 2024
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17. Change of Basis, Eigenbasis, and Quadratic Forms

Author: Walker, J. Douglas, primary and McLean, Noah M., additional
Published: 2024
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18. Rows and Columns

Author: Walker, J. Douglas, primary and McLean, Noah M., additional
Published: 2024
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19. Singular Value Decomposition

Author: Walker, J. Douglas, primary and McLean, Noah M., additional
Published: 2024
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20. When Does Ax = b have a Solution?

Author: Walker, J. Douglas, primary and McLean, Noah M., additional
Published: 2024
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21. Matrix Multiplication

Author: Walker, J. Douglas, primary and McLean, Noah M., additional
Published: 2024
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22. Determinants and Orthogonality

Author: Walker, J. Douglas, primary and McLean, Noah M., additional
Published: 2024
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23. Solving Ax= b When There is No Solution

Author: Walker, J. Douglas, primary and McLean, Noah M., additional
Published: 2024
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24. An Earth Science View of Eigenvalues and Eigenvectors

Author: Walker, J. Douglas, primary and McLean, Noah M., additional
Published: 2024
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25. Objective and subjective in vivo comparison of two emollient products

Author: Djokic-Gallagher J, Rosher P, Walker J, and Hart V
Subjects: Dermatology, RL1-803
Abstract: Jasmina Djokic-Gallagher,1 Phil Rosher,1 Jennine Walker,1 Valerie Hart21Research and Development Department, Dermal Laboratories Ltd, Hitchin, 2Reading Scientific Services Ltd, Reading Science Centre, Whiteknights Campus, University of Reading, Reading, UKBackground: Few studies have directly compared the effectiveness of different emollients in vivo, and the important matter of patient preference is generally overlooked.Methods: We report the results of an assessor-blinded, bilateral, concurrent comparison of two emollient pharmaceutical presentations, ie, Doublebase gel (DB) and Aqueous cream BP (AC), applied by 20 participants three times daily for 7 consecutive days. The primary efficacy endpoint was cumulative improvement in skin hydration measured by corneometry on days 1, 3, and 5 immediately before the first application and approximately 2 hours after the third application of the day. Secondary endpoints were investigator assessment of skin condition at these time points and participant assessment of product acceptability at the end of the study.Results: Both products increased skin hydration, but the effect of AC was relatively modest, with morning values readily returning to pretreatment levels. Hydration levels were higher for DB gel, maintained at all time points, and showed stepwise, cumulative increases over the 7 days of use. Overall patient satisfaction scores were higher for DB gel, and especially for “consistency,” “ease of use,” and “ease of absorption into the skin.” Eighty-five percent of participants expressed a desire to use DB gel again as compared with 40% for AC.Keywords: Doublebase, Aqueous cream, hydration, emollient, comparison
Published: 2012

26. Leveraging Micro-Bump Pitch Scaling to Accelerate Interposer Link Bandwidths for Future High-Performance Compute Applications.

Author: Walker J. Turner, John W. Poulton, Yoshinori Nishi, Xi Chen 0033, Brian Zimmer, Sanquan Song, John M. Wilson 0002, William J. Dally, and C. Thomas Gray
Published: 2024
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27. Searching for neutrinos from solar flares across solar cycles 23 and 24 with the Super-Kamiokande detector

Author: Okamoto, K., Abe, K., Hayato, Y., Hiraide, K., Hosokawa, K., Ieki, K., Ikeda, M., Kameda, J., Kanemura, Y., Kaneshima, Y., Kataoka, Y., Kashiwagi, Y., Miki, S., Mine, S., Miura, M., Moriyama, S., Nagao, Y., Nakahata, M., Nakano, Y., Nakayama, S., Noguchi, Y., Sato, K., Sekiya, H., Shimizu, K., Shiozawa, M., Shiba, H., Sonoda, Y., Suzuki, Y., Takeda, A., Takemoto, Y., Takenaka, A., Tanaka, H., Watanabe, S., Yano, T., Han, S., Kajita, T., Okumura, K., Tashiro, T., Tomiya, T., Wang, X., Xia, J., Yoshida, S., Megias, G. D., Fernandez, P., Labarga, L., Ospina, N., Zaldivar, B., Pointon, B. W., Kearns, E., Raaf, J. L., Wan, L., Wester, T., Bian, J., Griskevich, N. J., Kropp, W. R., Locke, S., Smy, M. B., Sobel, H. W., Takhistov, V., Yankelevich, A., Hill, J., Kim, J. Y., Lee, S. H., Lim, I. T., Moon, D. H., Park, R. G., Bodur, B., Scholberg, K., Walter, C. W., Beauchene, A., Bernard, L., Coffani, A., Drapier, O., Hedri, S. El, Giampaolo, A., Mueller, Th. A., Santos, A. D., Paganini, P., Quilain, B., Ishizuka, T., Nakamura, T., Jang, J. S., Learned, J. G., Choi, K., Cao, S., Anthony, L. H. V., Martin, D., Scott, M., Sztuc, A. A., Uchida, Y., Berardi, V., Catanesi, M. G., Radicioni, E., Calabria, N. F., Machado, L. N., De Rosa, G., Collazuol, G., Iacob, F., Lamoureux, M., Mattiazzi, M., Ludovici, L., Gonin, M., Pronost, G., Fujisawa, C., Maekawa, Y., Nishimura, Y., Friend, M., Hasegawa, T., Ishida, T., Kobayashi, T., Jakkapu, M., Matsubara, T., Nakadaira, T., Nakamura, K., Oyama, Y., Sakashita, K., Sekiguchi, T., Tsukamoto, T., Bhuiyan, N., Boschi, T., Burton, G. T., Di Lodovico, F., Gao, J., Goldsack, A., Katori, T., Migenda, J., Taani, M., Xie, Z., Zsoldos, S., Kotsar, Y., Ozaki, H., Suzuki, A. T., Takeuchi, Y., Yamamoto, S., Bronner, C., Feng, J., Kikawa, T., Mori, M., Nakaya, T., Wendell, R. A., Yasutome, K., Jenkins, S. J., McCauley, N., Mehta, P., Tarrant, A., Tsui, K. M., Fukuda, Y., Itow, Y., Menjo, H., Ninomiya, K., Lagoda, J., Lakshmi, S. M., Mandal, M., Mijakowski, P., Prabhu, Y. S., Zalipska, J., Jia, M., Jiang, J., Jung, C. K., Vilela, C., Wilking, M. J., Yanagisawa, C., Harada, M., Ishino, H., Ito, S., Kitagawa, H., Koshio, Y., Ma, W., Nakanishi, F., Piplani, N., Sakai, S., Barr, G., Barrow, D., Cook, L., Samani, S., Wark, D., Holin, A., Nova, F., Yang, J. Y., Fannon, J. E. P., Malek, M., McElwee, J. M., Stone, O., Thiesse, M. D., Thompson, L. F., Okazawa, H., Kim, S. B., Kwon, E., Seo, J. W., Yu, I., Ichikawa, A. K., Nakamura, K. D., Tairafune, S., Nishijima, K., Koshiba, M., Iwamoto, K., Nakagiri, K., Nakajima, Y., Shima, S., Taniuchi, N., Yokoyama, M., Martens, K., de Perio, P., Vagins, M. R., Kuze, M., Izumiyama, S., Inomoto, M., Ishitsuka, M., Ito, H., Kinoshita, T., Matsumoto, R., Ommura, Y., Shigeta, N., Shinoki, M., Suganuma, T., Yamauchi, K., Martin, J. F., Tanaka, H. A., Towstego, T., Akutsu, R., Gaur, R., Gousy-Leblanc, V., Hartz, M., Konaka, A., Li, X., Prouse, N. W., Chen, S., Xu, B. D., Zhang, B., Posiadala-Zezula, M., Boyd, S. B., Hadley, D., Nicholson, M., O'Flaherty, M., Richards, B., Ali, A., Jamieson, B., Walker, J., Marti, Ll., Minamino, A., Pintaudi, G., Sano, S., Sasaki, R., Suzuki, S., and Wada, K.
Subjects: Astrophysics - Solar and Stellar Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Experiment, Physics - Space Physics
Abstract: Neutrinos associated with solar flares (solar-flare neutrinos) provide information on particle acceleration mechanisms during the impulsive phase of solar flares. We searched using the Super-Kamiokande detector for neutrinos from solar flares that occurred during solar cycles $23$ and $24$, including the largest solar flare (X28.0) on November 4th, 2003. In order to minimize the background rate we searched for neutrino interactions within narrow time windows coincident with $\gamma$-rays and soft X-rays recorded by satellites. In addition, we performed the first attempt to search for solar-flare neutrinos from solar flares on the invisible side of the Sun by using the emission time of coronal mass ejections (CMEs). By selecting twenty powerful solar flares above X5.0 on the visible side and eight CMEs whose emission speed exceeds $2000$ $\mathrm{km \, s^{-1}}$ on the invisible side from 1996 to 2018, we found two (six) neutrino events coincident with solar flares occurring on the visible (invisible) side of the Sun, with a typical background rate of $0.10$ ($0.62$) events per flare in the MeV-GeV energy range. No significant solar-flare neutrino signal above the estimated background rate was observed. As a result we set the following upper limit on neutrino fluence at the Earth $\mathit{\Phi}<1.1\times10^{6}$ $\mathrm{cm^{-2}}$ at the $90\%$ confidence level for the largest solar flare. The resulting fluence limits allow us to constrain some of the theoretical models for solar-flare neutrino emission., Comment: 36 pages, 18 figures, 9 tables (Figure 12 was replaced because it was incorrect in version 1.)
Published: 2022

28. Neutron Tagging following Atmospheric Neutrino Events in a Water Cherenkov Detector

Author: Abe, K., Haga, Y., Hayato, Y., Hiraide, K., Ieki, K., Ikeda, M., Imaizumi, S., Iyogi, K., Kameda, J., Kanemura, Y., Kataoka, Y., Kato, Y., Kishimoto, Y., Miki, S., Mine, S., Miura, M., Mochizuki, T., Moriyama, S., Nagao, Y., Nakahata, M., Nakajima, T., Nakano, Y., Nakayama, S., Okada, T., Okamoto, K., Orii, A., Sato, K., Sekiya, H., Shiozawa, M., Sonoda, Y., Suzuki, Y., Takeda, A., Takemoto, Y., Takenaka, A., Tanaka, H., Tasaka, S., Tomura, T., Ueno, K., Watanabe, S., Yano, T., Yokozawa, T., Han, S., Irvine, T., Kajita, T., Kametani, I., Kaneyuki, K., Lee, K. P., McLachlan, T., Okumura, K., Richard, E., Tashiro, T., Wang, R., Xia, J., Megias, G. D., Bravo-Berguño, D., Labarga, L., Zaldivar, B., Goldhaber, M., Blaszczyk, F. d. M., Gustafson, J., Kachulis, C., Kearns, E., Raaf, J. L., Stone, J. L., Sulak, L. R., Sussman, S., Wan, L., Wester, T., Pointon, B. W., Bian, J., Carminati, G., Elnimr, M., Griskevich, N. J., Kropp, W. R., Locke, S., Renshaw, A., Smy, M. B., Sobel, H. W., Takhistov, V., Weatherly, P., Ganezer, K. S., Hartfiel, B. L., Hill, J., Keig, W. E., Hong, N., Kim, J. Y., Lim, I. T., Park, R. G., Akiri, T., Bodur, B., Himmel, A., Li, Z., O'Sullivan, E., Scholberg, K., Walter, C. W., Wongjirad, T., Bernard, L., Coffani, A., Drapier, O., Hedri, S. El, Giampaolo, A., Imber, J., Mueller, Th. A., Paganini, P., Quilain, B., Ishizuka, T., Nakamura, T., Jang, J. S., Choi, K., Learned, J. G., Matsuno, S., Smith, S. N., Amey, J., Anthony, L. H. V., Litchfield, R. P., Ma, W. Y., Marin, D., Sztuc, A. A., Uchida, Y., Wascko, M. O., Berardi, V., Catanesi, M. G., Intonti, R. A., Radicioni, E., Calabria, N. F., De Rosa, G., Machado, L. N., Collazuol, G., Iacob, F., Lamoureux, M., Ospina, N., Ludovici, L., Gonin, M., Pronost, G., Maekawa, Y., Nishimura, Y., Cao, S., Friend, M., Hasegawa, T., Ishida, T., Ishii, T., Jakkapu, M., Kobayashi, T., Matsubara, T., Nakadaira, T., Nakamura, K., Oyama, Y., Sakashita, K., Sekiguchi, T., Tsukamoto, T., Boschi, T., Di Lodovico, F., Migenda, J., Sedgwick, S. Molina, Taani, M., Zsoldos, S., Abe, KE., Hasegawa, M., Isobe, Y., Kotsar, Y., Miyabe, H., Ozaki, H., Shiozawa, T., Sugimoto, T., Suzuki, A. T., Takeuchi, Y., Yamamoto, S., Ali, A., Ashida, Y., Bronner, C., Feng, J., Hayashino, T., Hiraki, T., Hirota, S., Huang, K., Jiang, M., Kikawa, T., Mori, M., Murakami, A., Nakamura, KE., Nakaya, T., Patel, N. D., Suzuki, K., Takahashi, S., Tateishi, K., Wendell, R. A., Yasutome, K., Fernandez, P., McCauley, N., Mehta, P., Pritchard, A., Tsui, K. M., Fukuda, Y., Itow, Y., Menjo, H., Mitsuka, G., Murase, M., Muto, F., Niwa, T., Tsukada, T. Suzuki M., Frankiewicz, K., Mijakowski, P., Hignight, J., Jiang, J., Jung, C. K., Li, X., Palomino, J. L., Santucci, G., Vilela, C., Wilking, M. J., Yanagisawa, C., Fukuda, D., Hagiwara, K., Harada, M., Horai, T., Ishino, H., Ito, S., Kayano, T., Kibayashi, A., Kitagawa, H., Koshio, Y., Ma, W., Mori, T., Nagata, H., Piplani, N., Sakai, S., Sakuda, M., Takahira, Y., Xu, C., Yamaguchi, R., Kuno, Y., Barr, G., Barrow, D., Cook, L., Goldsack, A., Samani, S., Simpson, C., Wark, D., Nova, F., Tacik, R., Yang, J. Y., Cole, A., Jenkins, S. J., Malek, M., McElwee, J. M., Stone, O., Thiesse, M. D., Thompson, L. F., Okazawa, H., Choi, Y., Kim, S. B., Yu, I., Ichikawa, A. K., Ito, K., Nishijima, K., Calland, R. G., de Perio, P., Martens, K., Murdoch, M., Vagins, M. R., Koshiba, M., Totsuka, Y., Iwamoto, K., Nakajima, Y., Ogawa, N., Suda, Y., Yokoyama, M., Hamabe, D., Izumiyama, S., Kuze, M., Okajima, Y., Tanaka, M., Yoshida, T., Inomoto, M., Ishitsuka, M., Ito, H., Matsumoto, R., Ohta, K., Shinoki, M., Martin, J. F., Nantais, C. M., Tanaka, H. A., Towstego, T., Akutsu, R., Hartz, M., Konaka, A., Prouse, N. W., Chen, S., Xu, B. D., Zhang, Y., Berkman, S., Tobayama, S., Connolly, K., Wilkes, R. J., Posiadala-Zezula, M., Hadley, D., Richards, B., Jamieson, B., Walker, J., Marti, Ll., Minamino, A., Pintaudi, G., Sano, S., and Sasaki, R.
Subjects: High Energy Physics - Experiment, Astrophysics - Instrumentation and Methods for Astrophysics, Physics - Instrumentation and Detectors
Abstract: We present the development of neutron-tagging techniques in Super-Kamiokande IV using a neural network analysis. The detection efficiency of neutron capture on hydrogen is estimated to be 26%, with a mis-tag rate of 0.016 per neutrino event. The uncertainty of the tagging efficiency is estimated to be 9.0%. Measurement of the tagging efficiency with data from an Americium-Beryllium calibration agrees with this value within 10%. The tagging procedure was performed on 3,244.4 days of SK-IV atmospheric neutrino data, identifying 18,091 neutrons in 26,473 neutrino events. The fitted neutron capture lifetime was measured as 218 \pm 9 \mu s.
Published: 2022
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29. TAG: Learning Circuit Spatial Embedding From Layouts

Author: Zhu, Keren, Chen, Hao, Turner, Walker J., Kokai, George F., Wei, Po-Hsuan, Pan, David Z., and Ren, Haoxing
Subjects: Computer Science - Hardware Architecture, Computer Science - Machine Learning
Abstract: Analog and mixed-signal (AMS) circuit designs still rely on human design expertise. Machine learning has been assisting circuit design automation by replacing human experience with artificial intelligence. This paper presents TAG, a new paradigm of learning the circuit representation from layouts leveraging text, self-attention and graph. The embedding network model learns spatial information without manual labeling. We introduce text embedding and a self-attention mechanism to AMS circuit learning. Experimental results demonstrate the ability to predict layout distances between instances with industrial FinFET technology benchmarks. The effectiveness of the circuit representation is verified by showing the transferability to three other learning tasks with limited data in the case studies: layout matching prediction, wirelength estimation, and net parasitic capacitance prediction., Comment: Accepted by ICCAD 2022
Published: 2022

30. Implementing Fault-tolerant Entangling Gates on the Five-qubit Code and the Color Code

Author: Ryan-Anderson, C., Brown, N. C., Allman, M. S., Arkin, B., Asa-Attuah, G., Baldwin, C., Berg, J., Bohnet, J. G., Braxton, S., Burdick, N., Campora, J. P., Chernoguzov, A., Esposito, J., Evans, B., Francois, D., Gaebler, J. P., Gatterman, T. M., Gerber, J., Gilmore, K., Gresh, D., Hall, A., Hankin, A., Hostetter, J., Lucchetti, D., Mayer, K., Myers, J., Neyenhuis, B., Santiago, J., Sedlacek, J., Skripka, T., Slattery, A., Stutz, R. P., Tait, J., Tobey, R., Vittorini, G., Walker, J., and Hayes, D.
Subjects: Quantum Physics
Abstract: We compare two different implementations of fault-tolerant entangling gates on logical qubits. In one instance, a twelve-qubit trapped-ion quantum computer is used to implement a non-transversal logical CNOT gate between two five qubit codes. The operation is evaluated with varying degrees of fault tolerance, which are provided by including quantum error correction circuit primitives known as flagging and pieceable fault tolerance. In the second instance, a twenty-qubit trapped-ion quantum computer is used to implement a transversal logical CNOT gate on two [[7,1,3]] color codes. The two codes were implemented on different but similar devices, and in both instances, all of the quantum error correction primitives, including the determination of corrections via decoding, are implemented during runtime using a classical compute environment that is tightly integrated with the quantum processor. For different combinations of the primitives, logical state fidelity measurements are made after applying the gate to different input states, providing bounds on the process fidelity. We find the highest fidelity operations with the color code, with the fault-tolerant SPAM operation achieving fidelities of 0.99939(15) and 0.99959(13) when preparing eigenstates of the logical X and Z operators, which is higher than the average physical qubit SPAM fidelities of 0.9968(2) and 0.9970(1) for the physical X and Z bases, respectively. When combined with a logical transversal CNOT gate, we find the color code to perform the sequence--state preparation, CNOT, measure out--with an average fidelity bounded by [0.9957,0.9963]. The logical fidelity bounds are higher than the analogous physical-level fidelity bounds, which we find to be [0.9850,0.9903], reflecting multiple physical noise sources such as SPAM errors for two qubits, several single-qubit gates, a two-qubit gate and some amount of memory error.
Published: 2022

31. Protocol for the Brain Health Support Program Study of the Canadian Therapeutic Platform Trial for Multidomain Interventions to Prevent Dementia (CAN-THUMBS UP): A Prospective 12-Month Intervention Study

Author: Feldman, Howard H., Belleville, S., Nygaard, H. B., Montero-Odasso, M., Durant, J., Lupo, J.-L., Revta, C., Chan, S., Cuesta, M., Slack, P. J., Winer, S., Brewster, P. W. H., Hofer, S. M., Lim, A., Centen, A., Jacobs, D. M., Anderson, N. D., Walker, J. D., Speechley, M. R., Zou, G. Y., and Chertkow, H.
Published: 2023
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32. Search for supernova bursts in Super-Kamiokande IV

Author: collaboration, The Super-Kamiokande, Mori, M., Abe, K., Hayato, Y., Hiraide, K., Ieki, K., Ikeda, M., Imaizumi, S., Kameda, J., Kanemura, Y., Kaneshima, R., Kashiwagi, Y., Kataoka, Y., Miki, S., Mine, S., Miura, M., Moriyama, S., Nagao, Y., Nakahata, M., Nakano, Y., Nakayama, S., Noguchi, Y., Okada, T., Okamoto, K., Orii, A., Sato, K., Sekiya, H., Shiba, H., Shimizu, K., Shiozawa, M., Sonoda, Y., Suzuki, Y., Takeda, A., Takemoto, Y., Takenaka, A., Tanaka, H., Tomiya, T., Watanabe, S., Yano, T., Yoshida, S., Han, S., Kajita, T., Okumura, K., Tashiro, T., Wang, X., Xia, J., Megias, G. D., Bravo-Berguno, D., Fernandez, P., Labarga, L., Ospina, N., Zaldivar, B., Zsoldos, S., Pointon, B. W., Blaszczyk, F. d. M., Kearns, E., Raaf, J. L., Stone, J. L., Wan, L., Wester, T., Bian, J., Griskevich, N. J., Kropp, W. R., Locke, S., Smy, M. B., Sobel, H. W., Takhistov, V., Yankelevich, Hill, J., Kim, J. Y., Lim, I. T., Park, R. G., Bodur, B., Scholberg, K., Walter, C. W., Bernard, L., Coffani, A., Drapier, O., Hedri, S. El, Giampaolo, A., Mueller, Th. A., Paganini, P., Quilain, B., Santos, A. D., Ishizuka, T., Nakamura, T., Jang, J. S., Learned, J. G., Anthony, L. H. V., Martin, D., Scott, M., Sztuc, A. A., Uchida, Y., Berardi, V., Catanesi, M. G., Radicioni, E., Calabria, N. F., Machado, L. N., De Rosa, G., Collazuol, G., Iacob, F., Lamoureux, M., Mattiazzi, M., Ludovici, L., Gonin, M., Pronost, G., Maekawa, Y., Nishimura, Y., Fujisawa, C., Friend, M., Hasegawa, T., Ishida, T., Kobayashi, T., Jakkapu, M., Matsubara, T., Nakadaira, T., Nakamura, K., Oyama, Y., Sakashita, K., Sekiguchi, T., Tsukamoto, T., Ozaki, H., Shiozawa, T., Suzuki, A. T., Takeuchi, Y., Yamamoto, S., Kotsar, Y., Ashida, Y., Bronner, C., Feng, J., Hirota, S., Kikawa, T., Nakaya, T., Wendell, R. A., Yasutome, K., McCauley, N., Mehta, P., Tsui, K. M., Fukuda, Y., Itow, Y., Menjo, H., Ninomiya, K., Niwa, T., Tsukada, M., Lagoda, J., Lakshmi, S. M., Mijakowski, P., Zalipska, J., Mandal, M., Prabhu, Y. S., Jiang, J., Jung, C. K., Vilela, C., Wilking, M. J., Yanagisawa, C., Jia, M., Hagiwara, K., Harada, M., Horai, T., Ishino, H., Ito, S., Kitagawa, H., Koshio, Y., Ma, W., Nakanishi, F., Piplani, N., Sakai, S., Barr, G., Barrow, D., Cook, L., Samani, S., Wark, D., Nova, F., Boschi, T., Gao, J., Goldsack, A., Katori, T., Di Lodovico, F., Migenda, J., Taani, M., Yang, J. Y., Jenkins, S. J., Malek, M., McElwee, J. M., Stone, O., Thiesse, M. D., Thompson, L. F., Okazawa, H., Kim, S. B., Seo, J. W., Yu, I., Nishijima, K., Koshiba, M., Nakagiri, K., Nakajima, Y., Iwamoto, K., Taniuchi, N., Yokoyama, M., Martens, K., de Perio, P., Vagins, M. R., Kuze, M., Izumiyama, S., Yoshida, T., Inomoto, M., Ishitsuka, M., Ito, H., Kinoshita, T., Matsumoto, R., Ohta, K., Ommura, Y., Shigeta, N., Shinoki, M., Suganuma, T., Yamauchi, K., Martin, J. F., Tanaka, H. A., Towstego, T., Akutsu, R., Gousy-Leblanc, V., Hartz, M., Konaka, A., Prouse, N. W., Chen, S., Xu, B. D., Zhang, B., Posiadala-Zezula, M., Hadley, D., Nicholson, M., Flaherty, M. O', Richards, B., Ali, A., Jamieson, B., Walker, J., Marti, Ll., Minamino, A., Pintaudi, G., Sasaki, R., Sano, S., Suzuki, S., Wada, K., Cao, S., Ichikawa, A., Nakamura, K. D., and Tairafun, S.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Experiment
Abstract: Super-Kamiokande has been searching for neutrino bursts characteristic of core-collapse supernovae continuously, in real time, since the start of operations in 1996. The present work focuses on detecting more distant supernovae whose event rate may be too small to trigger in real time, but may be identified using an offline approach. The analysis of data collected from 2008 to 2018 found no evidence of distant supernovae bursts. This establishes an upper limit of 0.29 year$^{-1}$ on the rate of core-collapse supernovae out to 100 kpc at 90% C.L.. For supernovae that fail to explode and collapse directly to black holes the limit reaches to 300 kpc.
Published: 2022
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33. Protocol for the Brain Health Support Program Study of the Canadian Therapeutic Platform Trial for Multidomain Interventions to Prevent Dementia (CAN-THUMBS UP): A Prospective 12-Month Intervention Study.

Author: Belleville, S, Nygaard, H, Montero-Odasso, M, Durant, J, Lupo, J-L, Revta, C, Chan, S, Cuesta, M, Slack, P, Winer, S, Brewster, P, Hofer, S, Lim, A, Centen, A, Jacobs, D, Anderson, N, Walker, J, Speechley, M, Zou, G, Chertkow, H, and Feldman, Howard
Subjects: Alzheimer’s disease, Brain Health PRO, NCT05347966, dementia, prevention, Aged, Humans, Alzheimer Disease, Brain, Canada, Longitudinal Studies, Prospective Studies
Abstract: BACKGROUND/OBJECTIVES: CAN-THUMBS UP is designed as a comprehensive and innovative fully remote program to 1) develop an interactive and compelling online Brain Health Support Program intervention, with potential to positively influence dementia literacy, self-efficacy and lifestyle risk factors; 2) enroll and retain a community-dwelling Platform Trial Cohort of individuals at risk of dementia who will participate in the intervention; 3) support an open platform trial to test a variety of multidomain interventions that might further benefit individuals at risk of dementia. This manuscript presents the Brain Health Support Program Study protocol. DESIGN/SETTING: Twelve-month prospective multi-center longitudinal study to evaluate a fully remote web-based educational intervention. Participants will subsequently be part of a Platform Trial Cohort and may be eligible to participate in further dementia prevention clinical trials. PARTICIPANTS: Three hundred fifty older adults who are cognitively unimpaired or have mild cognitive impairment, with at least 1 well established dementia risk factor. INTERVENTION: Participants engage in the Brain Health Support Program intervention for 45-weeks and complete pre/post intervention measures. This intervention is designed to convey best available evidence for dementia prevention, consists of 181 chapters within 8 modules that are progressively delivered, and is available online in English and French. The program has been developed as a collaborative effort by investigators with recognized expertise in the programs content areas, along with input from older-adult citizen advisors. MEASUREMENTS: This study utilizes adapted remote assessments with accessible technologies (e.g. videoconferencing, cognitive testing via computer and mobile phone, wearable devices to track physical activity and sleep, self-administered saliva sample collection). The primary outcome is change in dementia literacy, as measured by the Alzheimers Disease Knowledge Scale. Secondary outcomes include change in self-efficacy; engagement using the online program; user satisfaction ratings; and evaluation of usability and acceptance. Exploratory outcomes include changes in attitudes toward dementia, modifiable risk factors, performance on the Neuropsychological Test Battery, performance on self-administered online cognitive assessments, and levels of physical activity and sleep; success of the national recruitment plan; and the distribution of age adjusted polygenic hazard scores. CONCLUSIONS: This fully remote study provides an accessible approach to research with all study activities being completed in the participants home environment. This approach may reduce barriers to participation, provide an easier and less demanding participant experience, and reach a broader geography with recruitment from all regions of Canada. CAN-THUMBS UP represents a Canadian contribution to the global World-Wide FINGERS program (alz.org/wwfingers).
Published: 2023

34. Coherent elastic neutrino-nucleus scattering: Terrestrial and astrophysical applications

Author: Abdullah, M., Abele, H., Akimov, D., Angloher, G., Aristizabal-Sierra, D., Augier, C., Balantekin, A. B., Balogh, L., Barbeau, P. S., Baudis, L., Baxter, A. L., Beaufort, C., Beaulieu, G., Belov, V., Bento, A., Berge, L., Bernardi, I. A., Billard, J., Bolozdynya, A., Bonhomme, A., Bres, G., Bret, J-. L., Broniatowski, A., Brossard, A., Buck, C., Cadeddu, M., Calvo, M., Canonica, L., Cappella, F., Cardani, L., Casali, N., Cazes, A., Cerulli, R., Chaize, D., Chang, C., Chapellier, M., Chaplinsky, L., Chemin, G., Chen, R., Colantoni, I., Colas, J., Coloma, P., Corcoran, E. C., Crawford, S., Cruciani, A., Fard, A. Dastgheibi, De Jesus, M., de Marcillac, P., De Romeri, V., del Castello, G., del GalloRoccagiovine, M., Delicato, D., Demarteau, M., Deng, Y., Dent, J. B., Denton, P. B., Dering, K., Doblhammer, A., Dordei, F., Dorer, S., Dumoulin, L., Dunford, D., Dutta, B., Erhart, A., Exshaw, O., Ferriol, S., Figueroa-Feliciano, E., Filippini, J. B., Flores, L . J., Formaggio, J. A., Friedl, M., Fuard, S., Gao, F., Garai, A., Garces, E. A., Gascon, J., Gehrlein, J., Gerbier, G., Ghete, V. M., Giomataris, I., Giroux, G., Giuliani, A., Giunti, C., Gorel, P., Goupy, C., Goupy, J., Goy, C., Green, M. P., Gros, M., Guerin, C., Guidi, V., Guillaudin, O., Guy, E., Ha, C., Hauff, D., Hakenmuller, J., Harrington, P. M., Hedges, S., Heine, S. T., Hertel, S., Heusch, M., Hoarau, C., Hoferichter, M., Hoppe, E. W., Hong, Z., Horiuchi, S., Huber, P., Ianigro, J. C., Jachowicz, N., Jericha, E., Jin, Y., Johnston, J. P., Juillard, A., Katsioulas, I., Kazarcev, S., Kaznacheeva, M., Kelly, F., Kelly, K. J., Kim, D., Kinast, A., Klinkenberg, L., Kluck, H., Knights, P., Ko, Y. J., Kosmas, T. S., Kwon, L., Lamblin, J., Lang, R. F., Langenkamper, A., Langrock, S., Lasserre, T., Lattaud, H., Lautridou, P., Lee, H. S., Lenardo, B. G., Lhuillier, D., Li, M., Li, S. C., Li, Y. F., Li, Z., Lindner, M., Liu, J., Loomba, D., Lubashevskiy, A., Machado, P. A. N., Mancuso, M., Maneschg, W., Markoff, D. M., Marnieros, S., Martin, R., Martin, R. D., Mauri, B., Mayer, D. W., Mazzolari, A., Mazzucato, E., Menendez, J., Minet, J., Miranda, O. G., Misiak, D., Mols, J. -P., Monfardini, A., Mounier, F., Muraz, J. F., Neep, T., Neilson, R., Newby, J., Newstead, J. L., Neyrial, H., Ni, K., Nikolopoulos, K., Nones, C., Norcini, D., Pandey, V., O'Brien, P., O'Hare, C. A. J., Oberauer, L., Oliver, W., Olivieri, E., Onillon, A., Oriol, C., Ortmann, T., Owen, R., Palladino, K. J., Papoulias, D. K., Park, J. C., Parno, D. S., Patel, P. K., Pattavina, L., Peinado, E., Perbet, E., Peters, L., Petricca, F., Pinckney, H. D., Piro, M. -C., Ponomarev, D., Poda, D., Potzel, W., Probst, F., Pucci, F., Rarbi, F., Rapp, R., Ray, H., Real, J. -S., Reindl, F., Rich, G. C., Ricol, J. S., Rink, T., Redon, T., Rogly, R., Robert, A., Rothe, J., Rozov, S., Rozova, I., Salagnac, T., Garcia, E. Sanchez, Garcia, G. Sanchez, Sanders, O., Sanglard, V., Santos, D., Sarkis, Y., Savu, V., Savvidis, G., Savvidis, I., Schermer, N., Schieck, J., Schmidt, B., Schonert, S., Scholberg, K., Schwenk, A., Schwertner, C., Scola, L., Shevchik, Ye., Shin, S., Sibille, V., Shoemaker, I. M., Snowden-Ifft, D. P., Soldner, T., Soum, G., Spooner, N. J. C., Stachurska, J., Stodolsky, L., Strauss, R., Strigari, L. E., Stutz, A., Suh, B. D., Suhonen, J., Tabrizi, Z., Takhistov, V., Thompson, A., Tomei, C., Tortola, M., Tripathi, M., Vagneron, L., Valle, J. W. F., Mirbach, K. v., Van De Ponteseele, W., Vignati, M., Vivier, M., Fernandez, F. Vazquez de Sola, Vezzu, F., Vidal, M., Wagner, V., Walker, J. W., Ward, R., Wex, A., Winslow, L., Wong, H. T., Wood, M. H., Xu, J., Yang, L., Yakushev, E., Zampaolo, M., Zettlemoyer, J., Zhang, Y. Y., and Zinatulina, D.
Subjects: High Energy Physics - Phenomenology, Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Experiment
Abstract: Coherent elastic neutrino-nucleus scattering (CE$\nu$NS) is a process in which neutrinos scatter on a nucleus which acts as a single particle. Though the total cross section is large by neutrino standards, CE$\nu$NS has long proven difficult to detect, since the deposited energy into the nucleus is $\sim$ keV. In 2017, the COHERENT collaboration announced the detection of CE$\nu$NS using a stopped-pion source with CsI detectors, followed up the detection of CE$\nu$NS using an Ar target. The detection of CE$\nu$NS has spawned a flurry of activities in high-energy physics, inspiring new constraints on beyond the Standard Model (BSM) physics, and new experimental methods. The CE$\nu$NS process has important implications for not only high-energy physics, but also astrophysics, nuclear physics, and beyond. This whitepaper discusses the scientific importance of CE$\nu$NS, highlighting how present experiments such as COHERENT are informing theory, and also how future experiments will provide a wealth of information across the aforementioned fields of physics., Comment: contribution to Snowmasss 2021. Contact authors: P. S. Barbeau, R. Strauss, L. E. Strigari
Published: 2022

35. EXCESS workshop: Descriptions of rising low-energy spectra

Author: Adari, P., Aguilar-Arevalo, A., Amidei, D., Angloher, G., Armengaud, E., Augier, C., Balogh, L., Banik, S., Baxter, D., Beaufort, C., Beaulieu, G., Belov, V., Gal, Y. Ben, Benato, G., Benoît, A., Bento, A., Bergé, L., Bertolini, A., Bhattacharyya, R., Billard, J., Bloch, I. M., Botti, A., Breier, R., Bres, G., Bret, J-. L., Broniatowski, A., Brossard, A., Bucci, C., Bunker, R., Cababie, M., Calvo, M., Camus, P., Cancelo, G., Canonica, L., Cappella, F., Cardani, L., Caron, J. -F., Casali, N., del Castello, G., Cazes, A., Cerulli, R., Vergara, B. A. Cervantes, Chaize, D., Chapellier, M., Chaplinsky, L., Charlieux, F., Chaudhuri, M., Chavarria, A. E., Chemin, G., Chen, R., Chen, H., Chierchie, F., Colantoni, I., Colas, J., Cooley, J., Coquillat, J. -M., Corcoran, E. C., Crawford, S., Crisler, M., Cruciani, A., Cushman, P., D'Addabbo, A., D'Olivo, J. C., Dastgheibi-Fard, A., De Jésus, M., Deng, Y., Dent, J. B., Depaoli, E. L., Dering, K., Dharani, S., Di Lorenzo, S., Drlica-Wagner, A., Dumoulin, L., Durnford, D., Dutta, B., Einfalt, L., Erb, A., Erhart, A., Essig, R., Estrada, J., Etzion, E., Exshaw, O., Favela-Perez, F., Feilitzsch, F. v., Moroni, G. Fernandez, Iachellini, N. Ferreiro, Ferriol, S., Fichtinger, S., Figueroa-Feliciano, E., Filippini, J. -B., Filosofov, D., Formaggio, J. A., Friedl, M., Fuard, S., Fuchs, D., Fuss, A., Gaïor, R., Garai, A., Garrah, C., Gascon, J., Gerbier, G., Ghaith, M., Ghete, V. M., Gift, D., Giomataris, I., Giroux, G., Giuliani, A., Gorel, P., Gorla, P., Goupy, C., Goupy, J., Goy, C., Gros, M., Gros, P., Guardincerri, Y., Guerin, C., Guidi, V., Guillaudin, O., Gupta, S., Guy, E., Harrington, P., Hauff, D., Heine, S. T., Hertel, S. A., Holland, S. E., Hong, Z., Hoppe, E. W., Hossbach, T. W., Ianigro, J. -C., Iyer, V., Jastram, A., Ješkovský, M., Jin, Y., Jochum, J., Johnston, J. P., Juillard, A., Karaivanov, D., Kashyap, V., Katsioulas, I., Kazarcev, S., Kaznacheeva, M., Kelly, F., Kilminster, B., Kinast, A., Klinkenberg, L., Kluck, H., Knights, P., Korn, Y., Kraus, H., von Krosigk, B., Kubik, A., Kurinsky, N. A., Lamblin, J., Langenkämper, A., Langrock, S., Lasserre, T., Lattaud, H., Lautridou, P., Lawson, I., Lee, S. J., Lee, M., Letessier-Selvon, A., Lhuillier, D., Li, M., Lin, Y. -T., Lubashevskiy, A., Mahapatra, R., Maludze, S., Mancuso, M., Manthos, I., Marini, L., Marnieros, S., Martin, R. D., Matalon, A., Matthews, J., Mauri, B., Mayer, D. W., Mazzolari, A., Mazzucato, E., Theenhausen, H. Meyer zu, Michielin, E., Minet, J., Mirabolfathi, N., Mirbach, K. v., Misiak, D., Mitra, P., Mocellin, J-. L., Mohanty, B., Mokina, V., Mols, J. -P., Monfardini, A., Mounier, F., Munagavalasa, S., Muraz, J. -F., Navick, X. -F., Neep, T., Neog, H., Neyrial, H., Nikolopoulos, K., Nilima, A., Nones, C., Novati, V., O'Brien, P., Oberauer, L., Olivieri, E., Olmi, M., Onillon, A., Oriol, C., Orly, A., Orrell, J. L., Ortmann, T., Overman, C. T., Pagliarone, C., Palušová, V., Pari, P., Patel, P. K., Pattavina, L., Petricca, F., Piers, A., Pinckney, H. D., Piro, M. -C., Platt, M., Poda, D., Ponomarev, D., Potzel, W., Povinec, P., Pröbst, F., Privitera, P., Pucci, F., Ramanathan, K., Real, J. -S., Redon, T., Reindl, F., Ren, R., Robert, A., Da Rocha, J., Rodrigues, D., Rogly, R., Rothe, J., Rowe, N., Rozov, S., Rozova, I., Saab, T., Saffold, N., Salagnac, T., Sander, J., Sanglard, V., Santos, D., Sarkis, Y., Savu, V., Savvidis, G., Savvidis, I., Schönert, S., Schäffner, K., Schermer, N., Schieck, J., Schmidt, B., Schmiedmayer, D., Schwertner, C., Scola, L., Settimo, M., Shevchik, Ye., Sibille, V., Sidelnik, I., Singal, A., Smida, R., Haro, M. Sofo, Soldner, T., Stachurska, J., Stahlberg, M., Stefanazzi, L., Stodolsky, L., Strandhagen, C., Strauss, R., Stutz, A., Thomas, R., Thompson, A., Tiffenberg, J., Tomei, C., Traina, M., Uemura, S., Usherov, I., Vagneron, L., Van De Pontseele, W., Fernandez, F. A. Vazquez de Sola, Vidal, M., Vignati, M., Virto, A. L., Vivier, M., Volansky, T., Wagner, V., Wagner, F., Walker, J., Ward, R., Watkins, S. L., Wex, A., Willers, M., Wilson, M. J., Winslow, L., Yakushev, E., Yu, T. -T., Zampaolo, M., Zaytsev, A., Zema, V., Zinatulina, D., and Zolotarova, A.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics, Physics - Instrumentation and Detectors
Abstract: Many low-threshold experiments observe sharply rising event rates of yet unknown origins below a few hundred eV, and larger than expected from known backgrounds. Due to the significant impact of this excess on the dark matter or neutrino sensitivity of these experiments, a collective effort has been started to share the knowledge about the individual observations. For this, the EXCESS Workshop was initiated. In its first iteration in June 2021, ten rare event search collaborations contributed to this initiative via talks and discussions. The contributing collaborations were CONNIE, CRESST, DAMIC, EDELWEISS, MINER, NEWS-G, NUCLEUS, RICOCHET, SENSEI and SuperCDMS. They presented data about their observed energy spectra and known backgrounds together with details about the respective measurements. In this paper, we summarize the presented information and give a comprehensive overview of the similarities and differences between the distinct measurements. The provided data is furthermore publicly available on the workshop's data repository together with a plotting tool for visualization., Comment: 44 pages, 20 figures; Editors: A. Fuss, M. Kaznacheeva, F. Reindl, F. Wagner; updated copyright statements and funding information
Published: 2022
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36. Longitudinal Study of Georgia's Pre-K Program: Third Grade Report

Author: University of North Carolina at Chapel Hill, FPG Child Development Institute, Soliday Hong, S., Zadrozny, S., Walker, J., Love, E. N. G., Osborne, J. D., Owen, J. L., Jenkins, G., and Peisner-Feinberg, E.
Abstract: The purpose of this study was to examine associations between attendance in Georgia's Pre-K Program and children's academic and social outcomes through third grade. This report includes a sub-study that incorporates a comparison group of children who did not attend any pre-k program. This report focuses on third grade outcomes, but it also includes pre-k to third grade outcomes collected during the 2013-2014 to 2017-2018 school years and a comparison sub-study of children who did not attend any pre-k. Study components include: (1) Standardized child assessments that measure skills across learning domains. By using standardized child assessments, children's scores can be compared to a nationally representative sample of children of the same age; (2) Observations of classroom quality over time that measure the quality of teacher-child interactions; (3) Inclusion of a subsample of dual language learners (English-Spanish); and (4) A comparison sample of children who did not attend any pre-k added in the third grade year. Children who attended Georgia's Pre-K Program had literacy skills that were moderately higher and executive function skills that were somewhat higher in the fall of third grade than children whose parents reported that the child did not attend any pre-k program (comparison group). These results are similar to the findings of the Longitudinal Study where children who attended Georgia's Pre-K had higher scores in foundational literacy skills relative to the national norming sample. Together, these results suggest that foundational literacy skills, which are a focus of pre-k, were not obtained by children in the comparison sample. [For the report summary, see ED611011.]
Published: 2021

37. Water-free patient care: a narrative review of the literature and discussion of the pressing need for a way forward

Author: Inkster, T., Walker, J., and Weinbren, M.
Published: 2024
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38. New Methods and Simulations for Cosmogenic Induced Spallation Removal in Super-Kamiokande-IV

Author: Collaboration, Super-Kamiokande, Locke, S., Coffani, A., Abe, K., Bronner, C., Hayato, Y., Ikeda, M., Imaizumi, S., Ito, H., Kameda, J., Kataoka, Y., Miura, M., Moriyama, S., Nagao, Y., Nakahata, M., Nakajima, Y., Nakayama, S., Okada, T., Okamoto, K., Orii, A., Pronost, G., Sekiya, H., Shiozawa, M., Sonoda, Y., Suzuki, Y., Takeda, A., Takemoto, Y., Takenaka, A., Tanaka, H., Yano, T., Hirade, K., Kanemura, Y., Miki, S., Watabe, S., Han, S., Kajita, T., Okumura, K., Tashiro, T., Xia, J., Wang, X., Megias, G. D., Bravo-Berguño, D., Labarga, L., Marti, Ll., Zaldivar, B., Pointon, B. W., Blaszczyk, F. d. M., Kearns, E., Raaf, J. L., Stone, J. L., Wan, L., Wester, T., Bian, J., Griskevich, N. J., Kropp, W. R., Mine, S., Yankelevic, A., Smy, M. B., Sobel, H. W., Takhistov, V., Hill, J., Kim, J. Y., Lim, I. T., Park, R. G., Bodur, B., Scholberg, K., Walter, C. W., Bernard, L., Drapier, O., Hedri, S. El, Giampaolo, A., Gonin, M., Mueller, Th. A., Paganini, P., Quilain, B., Santos, A. D., Ishizuka, T., Nakamura, T., Jang, J. S., Learned, J. G., Anthony, L. H. V., Sztuc, A. A., Uchida, Y., Martin, D., Scott, M., Berardi, V., Catanesi, M. G., Radicioni, E., Calabria, N. F., Machado, L. N., De Rosa, G., Collazuol, G., Iacob, F., Lamoureux, M., Ospina, N., Mattiazzi, M., Ludovici, L., Nishimura, Y., Maewaka, Y., Cao, S., Friend, M., Hasegawa, T., Ishida, T., Kobayashi, T., Jakkapu, M., Matsubara, T., Nakadaira, T., Nakamura, K., Oyama, Y., Sakashita, K., Sekiguchi, T., Tsukamoto, T., Nakano, Y., Shiozawa, T., Suzuki, A. T., Takeuchi, Y., Yamamoto, S., Kotsar, Y., Ozaki, H., Ali, A., Ashida, Y., Feng, J., Hirota, S., Ichikawa, A. K., Kikawa, T., Mori, M., Nakaya, T., Wendell, R. A., Yasutome, K., Fernandez, P., McCauley, N., Mehta, P., Tsui, K. M., Fukuda, Y., Itow, Y., Menjo, H., Niwa, T., Sato, K., Tsukada, M., Mijakowski, P., Lagoda, J., Lakshmi, S. M., Zalipska, J., Jung, C. K., Vilela, C., Wilking, M. J., Yanagisawa, C., Jiang, J., Hagiwara, K., Harada, M., Horai, T., Ishino, H., Ito, S., Koshio, Y., Ma, W., Piplani, N., Sakai, S., Kitagawa, H., Barr, G., Barrow, D., Cook, L., Goldsack, A., Samani, S., Wark, D., Nova, F., Boschi, T., Di Lodovico, F., Taani, M., Zsoldos, S., Gao, J., Migenda, J., Yang, J. Y., Jenkins, S. J., Malek, M., McElwee, J. M., Stone, O., Thiesse, M. D., Thompson, L. F., Okazawa, H., Kim, S. B., Yu, I., Seo, J. W., Nishijima, K., Koshiba, M., Iwamoto, K., Ogawa, N., Yokoyama, M., Martens, K., Vagins, M. R., Nakagiri, K., Kuze, M., Izumiyama, S., Yoshida, T., Inomoto, M., Ishitsuka, M., Matsumoto, R., Ohta, K., Shinoki, M., Suganuma, T., Kinoshita, T., Martin, J. F., Tanaka, H. A., Towstego, T., Akutsu, R., Hartz, M., Konaka, A., de Perio, P., Prouse, N. W., Chen, S., Xu, B. D., Zhang, Y., Posiadala-Zezula, M., Richards, B., Jamieson, B., Walker, J., Minamino, A., Pintaudi, G., and Sasaki, R.
Subjects: High Energy Physics - Experiment, Astrophysics - High Energy Astrophysical Phenomena
Abstract: Radioactivity induced by cosmic muon spallation is a dominant source of backgrounds for $\mathcal{O}(10)~$MeV neutrino interactions in water Cherenkov detectors. In particular, it is crucial to reduce backgrounds to measure the solar neutrino spectrum and find neutrino interactions from distant supernovae. In this paper we introduce new techniques to locate muon-induced hadronic showers and efficiently reject spallation backgrounds. Applying these techniques to the solar neutrino analysis with an exposure of $2790\times22.5$~kton.day increases the signal efficiency by $12.6\%$, approximately corresponding to an additional year of detector running. Furthermore, we present the first spallation simulation at SK, where we model hadronic interactions using FLUKA. The agreement between the isotope yields and shower pattern in this simulation and in the data gives confidence in the accuracy of this simulation, and thus opens the door to use it to optimize muon spallation removal in new data with gadolinium-enhanced neutron capture detection.
Published: 2021

39. Queering Labels: Expanding Identity Categories in LGBTQ + Research and Clinical Practice

Author: Garrett-Walker, J. J. and Montagno, Michelle J.
Abstract: Current understandings of gender and sexual identities are limited given the diversity of the LGBTQ + community. Researchers and clinicians are constantly challenged by the ever-expanding identity options. The current analysis seeks to bring awareness to the importance of moving beyond traditional binary gender identity and sexual identity categories when working with Millennial and Generation Z LGBTQ + populations. A sample of 1863 LGBTQ + young adults (M[subscript age] = 19.54, SD = 3.33, range= 18-35) reported on their gender identities and sexual identities. We found that 40% of our sample endorsed an expansive sexual identity while 34% endorsed an expansive gender identity. We also found differences between participants based on generational cohorts. Generation Z participants were more likely to report an expansive gender and sexual identity, when compared to Millennials. This data serves to inform researchers and clinicians as they continue work with, and serve, LGBTQ + communities.
Published: 2023
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40. Transitioning to a new Casemix grouper to fund long-term care homes in Ontario, Canada

Author: Alshurafa M, Hoy C, Yu K, Temple P, Walker J, and Tsui S
Subjects: Public aspects of medicine, RA1-1270
Published: 2011
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41. Diffuse Supernova Neutrino Background Search at Super-Kamiokande

Author: Collaboration, Super-Kamiokande, Abe, K., Bronner, C., Hayato, Y., Hiraide, K., Ikeda, M., Imaizumi, S., Kameda, J., Kanemura, Y., Kataoka, Y., Miki, S., Miura, M., Moriyama, S., Nagao, Y., Nakahata, M., Nakayama, S., Okada, T., Okamoto, K., Orii, A., Pronost, G., Sekiya, H., Shiozawa, M., Sonoda, Y., Suzuki, Y., Takeda, A., Takemoto, Y., Takenaka, A., Tanaka, H., Watanabe, S., Yano, T., Han, S., Kajita, T., Okumura, K., Tashiro, T., Xia, J., Megias, G. D., Bravo-Bergu, D., Labarga, L., Marti, Ll., Zaldivar, B., Pointon, B. W., Blaszczyk, F. d. M., Kearns, E., Raaf, J. L., Stone, J. L., Wan, L., Wester, T., Bian, J., Griskevich, N. J., Kropp, W. R., Locke, S., Mine, S., Smy, M. B., Sobel, H. W., Takhistov, V., Hill, J., Kim, J. Y., Lim, I. T., Park, R. G., Bodur, B., Scholberg, K., Walter, C. W., Cao, S., Bernard, L., Coffani, A., Drapier, O., Hedri, S. El, Giampaolo, A., Gonin, M., Mueller, Th. A., Paganini, P., Quilain, B., Ishizuka, T., Nakamura, T., Jang, J. S., Learned, J. G., Anthony, L. H. V., Martin, D., Scott, M., Sztuc, A. A., Uchida, Y., Berardi, V., Catanesi, M. G., Radicioni, E., Calabria, N. F., Machado, L. N., De Rosa, G., Collazuol, G., Iacob, F., Lamoureux, M., Mattiazzi, M., Ospina, N., Ludovici, L., Maekawa, Y., Nishimura, Y., Friend, M., Hasegawa, T., Ishida, T., Kobayashi, T., Jakkapu, M., Matsubara, T., Nakadaira, T., Nakamura, K., Oyama, Y., Sakashita, K., Sekiguchi, T., Tsukamoto, T., Kotsar, Y., Nakano, Y., Ozaki, H., Shiozawa, T., Suzuki, A. T., Takeuchi, Y., Yamamoto, S., Ali, A., Ashida, Y., Feng, J., Hirota, S., Kikawa, T., Mori, M., Nakaya, T., Wendell, R. A., Yasutome, K., Fernandez, P., McCauley, N., Mehta, P., Tsui, K. M., Fukuda, Y., Itow, Y., Menjo, H., Niwa, T., Sato, K., Tsukada, M., Lagoda, J., Lakshmi, S. M., Mijakowski, P., Zalipska, J., Jiang, J., Jung, C. K., Vilela, C., Wilking, M. J., Yanagisawa, C., Hagiwara, K., Harada, M., Horai, T., Ishino, H., Ito, S., Kitagawa, H., Koshio, Y., Ma, W., Piplani, N., Sakai, S., Barr, G., Barrow, D., Cook, L., Goldsack, A., Samani, S., Wark, D., Nova, F., Boschi, T., Di Lodovico, F., Gao, J., Migenda, J., Taani, M., Zsoldos, S., Yang, J. Y., Jenkins, S. J., Malek, M., McElwee, J. M., Stone, O., Thiesse, M. D., Thompson, L. F., Okazawa, H., Kim, S. B., Seo, J. W., Yu, I., Nishijima, K., Koshiba, M., Iwamoto, K., Nakagiri, K., Nakajima, Y., Ogawa, N., Yokoyama, M., Martens, K., Vagins, M. R., Kuze, M., Izumiyama, S., Yoshida, T., Inomoto, M., Ishitsuka, M., Ito, H., Kinoshita, T., Matsumoto, R., Ohta, K., Shinoki, M., Suganuma, T., Ichikawa, A. K., Martin, J. F., Tanaka, H. A., Towstego, T., Akutsu, R., Gousy-Leblanc, V., Hartz, M., Konaka, A., de Perio, P., Prouse, N. W., Chen, S., Xu, B. D., Zhang, Y., Posiadala-Zezula, M., Hadley, D., O'Flaherty, M., Richards, B., Jamieson, B., Walker, J., Minamino, A., Pintaudi, G., Sano, S., and Sasaki, R.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Experiment
Abstract: A new search for the diffuse supernova neutrino background (DSNB) flux has been conducted at Super-Kamiokande (SK), with a $22.5\times2970$-kton$\cdot$day exposure from its fourth operational phase IV. The new analysis improves on the existing background reduction techniques and systematic uncertainties and takes advantage of an improved neutron tagging algorithm to lower the energy threshold compared to the previous phases of SK. This allows for setting the world's most stringent upper limit on the extraterrestrial $\bar{\nu}_e$ flux, for neutrino energies below 31.3 MeV. The SK-IV results are combined with the ones from the first three phases of SK to perform a joint analysis using $22.5\times5823$ kton$\cdot$days of data. This analysis has the world's best sensitivity to the DSNB $\bar{\nu}_e$ flux, comparable to the predictions from various models. For neutrino energies larger than 17.3 MeV, the new combined $90\%$ C.L. upper limits on the DSNB $\bar{\nu}_e$ flux lie around $2.7$ cm$^{-2}$$\cdot$$\text{sec}^{-1}$, strongly disfavoring the most optimistic predictions. Finally, potentialities of the gadolinium phase of SK and the future Hyper-Kamiokande experiment are discussed., Comment: 42 pages, 37 figures, 14 tables
Published: 2021
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42. First Gadolinium Loading to Super-Kamiokande

Author: Abe, K., Bronner, C., Hayato, Y., Hiraide, K., Ikeda, M., Imaizumi, S., Kameda, J., Kanemura, Y., Kataoka, Y., Miki, S., Miura, M., Moriyama, S., Nagao, Y., Nakahata, M., Nakayama, S., Okada, T., Okamoto, K., Orii, A., Pronost, G., Sekiya, H., Shiozawa, M., Sonoda, Y., Suzuki, Y., Takeda, A., Takemoto, Y., Takenaka, A., Tanaka, H., Watanabe, S., Yano, T., Han, S., Kajita, T., Okumura, K., Tashiro, T., Xia, J., Megias, G. D., Bravo-Berguno, D., Labarga, L., Marti, Ll., Zaldivar, B., Pointon, B. W., Blaszczyk, F. d. M., Kearns, E., Raaf, J. L., Stone, J. L., Wan, L., Wester, T., Bian, J., Griskevich, N. J., Kropp, W. R., Locke, S., Mine, S., Smy, M. B., Sobel, H. W., Takhistov, V., Hill, J., Kim, J. Y., Lim, I. T., Park, R. G., Bodur, B., Scholberg, K., Walter, C. W., Bernard, L., Coffani, A., Drapier, O., Hedri, S. El, Giampaolo, A., Gonin, M., Mueller, Th. A., Paganini, P., Quilain, B., Ishizuka, T., Nakamura, T., Jang, J. S., Learned, J. G., Anthony, L. H. V., Martin, D., Scott, M., Sztuc, A. A., Uchida, Y., Cao, S., Berardi, V., Catanesi, M. G., Radicioni, E., Calabria, N. F., Machado, L. N., De Rosa, G., Collazuol, G., Iacob, F., Lamoureux, M., Mattiazzi, M., Ospina, N., Ludovici, L., Maekawa, Y., Nishimura, Y., Friend, M., Hasegawa, T., Ishida, T., Kobayashi, T., Jakkapu, M., Matsubara, T., Nakadaira, T., Nakamura, K., Oyama, Y., Sakashita, K., Sekiguchi, T., Tsukamoto, T., Boschi, T., Gao, J., Di Lodovico, F., Migenda, J., Taani, M., Zsoldos, S., Kotsar, Y., Nakano, Y., Ozaki, H., Shiozawa, T., Suzuki, A. T., Takeuchi, Y., Yamamoto, S., Ali, A., Ashida, Y., Feng, J., Hirota, S., Kikawa, T., Mori, M., Nakaya, T., Wendell, R. A., Yasutome, K., Fernandez, P., McCauley, N., Mehta, P., Tsui, K. M., Fukuda, Y., Itow, Y., Menjo, H., Niwa, T., Sato, K., Tsukada, M., Lagoda, J., Lakshmi, S. M., Mijakowski, P., Zalipska, J., Jiang, J., Jung, C. K., Vilela, C., Wilking, M. J., Yanagisawa, C., Hagiwara, K., Harada, M., Horai, T., Ishino, H., Ito, S., Kitagawa, F., Koshio, Y., Ma, W., Piplani, N., Sakai, S., Barr, G., Barrow, D., Cook, L., Goldsack, A., Samani, S., Wark, D., Nova, F., Yang, J. Y., Jenkins, S. J., Malek, M., McElwee, J. M., Stone, O., Thiesse, M. D., Thompson, L. F., Okazawa, H., Kim, S. B., Seo, J. W., Yu, I., Ichikawa, A. K., Nishijima, K., Koshiba, M., Iwamoto, K., Nakajima, Y., Ogawa, N., Yokoyama, M., Martens, K., Vagins, M. R., Kuze, M., Izumiyama, S., Yoshida, T., Inomoto, M., Ishitsuka, M., Ito, H., Kinoshita, T., Matsumoto, R., Ohta, K., Shinoki, M., Suganuma, T., Martin, J. F., Tanaka, H. A., Towstego, T., Akutsu, R., Hartz, M., Konaka, A., de Perio, P., Prouse, N. W., Chen, S., Xu, B. D., Posiadala-Zezula, M., Hadley, D., O'Flaherty, M., Richards, B., Jamieson, B., Walker, J., Minamino, A., Pintaudi, G., Sano, S., and Sasaki, R.
Subjects: Physics - Instrumentation and Detectors, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: In order to improve Super-Kamiokande's neutron detection efficiency and to thereby increase its sensitivity to the diffuse supernova neutrino background flux, 13 tons of $\rm Gd_2(\rm SO_4)_3\cdot \rm 8H_2O$ (gadolinium sulfate octahydrate) was dissolved into the detector's otherwise ultrapure water from July 14 to August 17, 2020, marking the start of the SK-Gd phase of operations. During the loading, water was continuously recirculated at a rate of 60 m$^3$/h, extracting water from the top of the detector and mixing it with concentrated $\rm Gd_2(\rm SO_4)_3\cdot \rm 8H_2O$ solution to create a 0.02% solution of the Gd compound before injecting it into the bottom of the detector. A clear boundary between the Gd-loaded and pure water was maintained through the loading, enabling monitoring of the loading itself and the spatial uniformity of the Gd concentration over the 35 days it took to reach the top of the detector. During the subsequent commissioning the recirculation rate was increased to 120 m$^3$/h, resulting in a constant and uniform distribution of Gd throughout the detector and water transparency equivalent to that of previous pure-water operation periods. Using an Am-Be neutron calibration source the mean neutron capture time was measured to be $115\pm1$ $\mu$s, which corresponds to a Gd concentration of $111\pm2$ ppm, as expected for this level of Gd loading. This paper describes changes made to the water circulation system for this detector upgrade, the Gd loading procedure, detector commissioning, and the first neutron calibration measurements in SK-Gd., Comment: 37 pages, 19 Figures, Accepted for publication in Nucl. Instrum. Meth. A
Published: 2021
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43. Coupling of magnetic and optomechanical structuring in cold atoms

Author: Ackemann, T., Labeyrie, G., Boquete, A. Costa, Baio, G., Walker, J. G. M., Kaiser, R., Oppo, G. -L., and Robb, G. R. M.
Subjects: Quantum Physics, Nonlinear Sciences - Pattern Formation and Solitons, Physics - Atomic Physics, Physics - Optics
Abstract: Self-organized phases in cold atoms as a result of light-mediated interactions can be induced by coupling to internal or external degrees of the atoms. There has been growing interest in the interaction of internal spin degrees of freedom with the optomechanical dynamics of the external centre-of-mass motion. We present a model for the coupling between magnetic and optomechanical structuring in a $J=1/2 \to J'=3/2$ system in a single-mirror feedback scheme, being representative for a larger class of diffractively coupled systems such as longitudinally pumped cavities and counter-propagating beam schemes. For negative detunings, a linear stability analysis demonstrates that optical pumping and optomechanical driving cooperate to create magnetic ordering. However, for long-period transmission gratings the magnetic driving will strongly dominate the optomechanical driving, unless one operates very close to the existence range of the magnetic instability. At small lattice periods, in particular at wavelength-scale periods, the optomechanical driving will dominate.
Published: 2021
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44. Predicting climate impacts to the Olympic Games and FIFA Men's World Cups from 2022 to 2032

Author: Ross, Walker J., primary and Orr, Madeleine, additional
Published: 2023
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45. 237Np Fission Spectrum Cumulative Fission Product Yield Measurement Using Godiva IV Critical Assembly

Author: Tamashiro, A.S., Harke, J.T., Duarte, J.G., Mishnayot, Y., Burcher, S., Padgett, S.W., Zhao, P., Pierson, B.D., Gharibyan, N., Goda, J.M., Greenwood, L.R., Hayes, D.K., Hutchinson, J., Harward, N., Roberts, K., Slavik, G., Yap-Chiongco, P., Walker, J., and Palmer, C.J.
Published: 2024
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46. ICD-10 diagnosis codes in electronic health records do not adequately capture fracture complexity for proximal humerus fractures

Author: Floyd, Sarah B., Walker, J. Todd, Smith, Justin T., Jones, Patrick E., Boes, Nathan, Lindros, Sydney, Carroll, Maile, Brooks, John M., Thigpen, Charles A., Pill, Stephan G., and Kissenberth, Michael J.
Published: 2024
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47. The SNO+ Experiment

Author: Collaboration, SNO, Albanese, V., Alves, R., Anderson, M. R., Andringa, S., Anselmo, L., Arushanova, E., Asahi, S., Askins, M., Auty, D. J., Back, A. R., Back, S., Barão, F., Barnard, Z., Barr, A., Barros, N., Bartlett, D., Bayes, R., Beaudoin, C., Beier, E. W., Berardi, G., Bialek, A., Biller, S. D., Blucher, E., Bonventre, R., Boulay, M., Braid, D., Caden, E., Callaghan, E. J., Caravaca, J., Carvalho, J., Cavalli, L., Chauhan, D., Chen, M., Chkvorets, O., Clark, K. J., Cleveland, B., Connors, C., Cookman, D., Coulter, I. T., Cox, M. A., Cressy, D., Dai, X., Darrach, C., Davis-Purcell, B., Deluce, C., Depatie, M. M., Descamps, F., Di Lodovico, F., Dittmer, J., Doxtator, A., Duhaime, N., Duncan, F., Dunger, J., Earle, A. D., Fabris, D., Falk, E., Farrugia, A., Fatemighomi, N., Felber, C., Fischer, V., Fletcher, E., Ford, R., Frankiewicz, K., Gagnon, N., Gaur, A., Gauthier, J., Gibson-Foster, A., Gilje, K., González-Reina, O. I., Gooding, D., Gorel, P., Graham, K., Grant, C., Grove, J., Grullon, S., Guillian, E., Hall, S., Hallin, A. L., Hallman, D., Hans, S., Hartnell, J., Harvey, P., Hedayatipour, M., Heintzelman, W. J., Heise, J., Helmer, R. L., Hodak, B., Hodak, M., Hood, M., Horne, D., Hreljac, B., Hu, J., Hussain, S. M. A., Iida, T., Inácio, A. S., Jackson, C. M., Jelley, N. A., Jillings, C. J., Jones, C., Jones, P. G., Kamdin, K., Kaptanoglu, T., Kaspar, J., Keeter, K., Kefelian, C., Khaghani, P., Kippenbrock, L., Klein, J. R., Knapik, R., Kofron, J., Kormos, L. L., Korte, S., Krar, B., Kraus, C., Krauss, C. B., Kroupová, T., Labe, K., Lafleur, F., Lam, I., Lan, C., Land, B. J., Lane, R., Langrock, S., Larochelle, P., Larose, S., LaTorre, A., Lawson, I., Lebanowski, L., Lefeuvre, G. M., Leming, E. J., Li, A., Li, O., Lidgard, J., Liggins, B., Liimatainen, P., Lin, Y. H., Liu, X., Liu, Y., Lozza, V., Luo, M., Maguire, S., Maio, A., Majumdar, K., Manecki, S., Maneira, J., Martin, R. D., Marzec, E., Mastbaum, A., Mathewson, A., McCauley, N., McDonald, A. B., McFarlane, K., Mekarski, P., Meyer, M., Miller, C., Mills, C., Mlejnek, M., Mony, E., Morissette, B., Morton-Blake, I., Mottram, M. J., Nae, S., Nirkko, M., Nolan, L. J., Novikov, V. M., O'Keeffe, H. M., O'Sullivan, E., Gann, G. D. Orebi, Parnell, M. J., Paton, J., Peeters, S. J. M., Pershing, T., Petriw, Z., Petzoldt, J., Pickard, L., Pracsovics, D., Prior, G., Prouty, J. C., Quirk, S., Read, S., Reichold, A., Riccetto, S., Richardson, R., Rigan, M., Ritchie, I., Robertson, A., Robertson, B. C., Rose, J., Rosero, R., Rost, P. M., Rumleskie, J., Schumaker, M. A., Schwendener, M. H., Scislowski, D., Secrest, J., Seddighin, M., Segui, L., Seibert, S., Semenec, I., Shaker, F., Shantz, T., Sharma, M. K., Shokair, T. M., Sibley, L., Sinclair, J. R., Singh, K., Skensved, P., Smiley, M., Sonley, T., Sörensen, A., St-Amant, M., Stainforth, R., Stankiewicz, S., Strait, M., Stringer, M. I., Stripay, A., Svoboda, R., Tacchino, S., Tam, B., Tanguay, C., Tatar, J., Tian, L., Tolich, N., Tseng, J., Tseung, H. W. C., Turner, E., Van Berg, R., Vázquez-Jáuregui, E., Veinot, J. G. C., Virtue, C. J., von Krosigk, B., Walker, J. M. G., Walker, M., Wallig, J., Walton, S. C., Wang, J., Ward, M., Wasalski, O., Waterfield, J., Weigand, J. J., White, R. F., Wilson, J. R., Winchester, T. J., Woosaree, P., Wright, A., Yanez, J. P., Yeh, M., Zhang, T., Zhang, Y., Zhao, T., Zuber, K., and Zummo, A.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment, Nuclear Experiment
Abstract: The SNO+ experiment is located 2 km underground at SNOLAB in Sudbury, Canada. A low background search for neutrinoless double beta ($0\nu\beta\beta$) decay will be conducted using 780 tonnes of liquid scintillator loaded with 3.9 tonnes of natural tellurium, corresponding to 1.3 tonnes of $^{130}$Te. This paper provides a general overview of the SNO+ experiment, including detector design, construction of process plants, commissioning efforts, electronics upgrades, data acquisition systems, and calibration techniques. The SNO+ collaboration is reusing the acrylic vessel, PMT array, and electronics of the SNO detector, having made a number of experimental upgrades and essential adaptations for use with the liquid scintillator. With low backgrounds and a low energy threshold, the SNO+ collaboration will also pursue a rich physics program beyond the search for $0\nu\beta\beta$ decay, including studies of geo- and reactor antineutrinos, supernova and solar neutrinos, and exotic physics such as the search for invisible nucleon decay. The SNO+ approach to the search for $0\nu\beta\beta$ decay is scalable: a future phase with high $^{130}$Te-loading is envisioned to probe an effective Majorana mass in the inverted mass ordering region., Comment: 61 pages, 23 figures, 4 tables
Published: 2021
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48. Search for neutrinos in coincidence with gravitational wave events from the LIGO-Virgo O3a Observing Run with the Super-Kamiokande detector

Author: collaboration, The Super-Kamiokande, Abe, K., Bronner, C., Hayato, Y., Ikeda, M., Imaizumi, S., Kameda, J., Kanemura, Y., Kataoka, Y., Miki, S., Miura, M., Moriyama, S., Nagao, Y., Nakahata, M., Nakayama, S., Okada, T., Okamoto, K., Orii, A., Pronost, G., Sekiya, H., Shiozawa, M., Sonoda, Y., Suzuki, Y., Takeda, A., Takemoto, Y., Takenaka, A., Tanaka, H., Watanabe, S., Yano, T., Han, S., Kajita, T., Okumura, K., Tashiro, T., Wang, R., Xia, J., Megias, G. D., Bravo-Berguño, D., Labarga, L., Marti, Ll., Zaldivar, B., Pointon, B. W., Blaszczyk, F. d. M., Kearns, E., Raaf, J. L., Stone, J. L., Wan, L., Wester, T., Bian, J., Griskevich, N. J., Kropp, W. R., Locke, S., Mine, S., Smy, M. B., Sobel, H. W., Takhistov, V., Weatherly, P., Hill, J., Kim, J. Y., Lim, I. T., Park, R. G., Bodur, B., Scholberg, K., Walter, C. W., Bernard, L., Coffani, A., Drapier, O., Hedri, S. El, Giampaolo, A., Gonin, M., Mueller, Th. A., Paganini, P., Quilain, B., Ishizuka, T., Nakamura, T., Jang, J. S., Learned, J. G., Anthony, L. H. V., Martin, D. G. R., Sztuc, A. A., Uchida, Y., Berardi, V., Catanesi, M. G., Radicioni, E., Calabria, N. F., Machado, L. N., De Rosa, G., Collazuol, G., Iacob, F., Lamoureux, M., Ospina, N., Ludovici, L., Maekawa, Y., Nishimura, Y., Cao, S., Friend, M., Hasegawa, T., Ishida, T., Jakkapu, M., Kobayashi, T., Matsubara, T., Nakadaira, T., Nakamura, K., Oyama, Y., Sakashita, K., Sekiguchi, T., Tsukamoto, T., Kotsar, Y., Nakano, Y., Ozaki, H., Shiozawa, T., Suzuki, A. T., Takeuchi, Y., Yamamoto, S., Ali, A., Ashida, Y., Feng, J., Hirota, S., Kikawa, T., Mori, M., Nakaya, T., Wendell, R. A., Yasutome, K., Fernandez, P., McCauley, N., Mehta, P., Pritchard, A., Tsui, K. M., Fukuda, Y., Itow, Y., Menjo, H., Niwa, T., Sato, K., Tsukada, M., Mijakowski, P., Jiang, J., Jung, C. K., Vilela, C., Wilking, M. J., Yanagisawa, C., Hagiwara, K., Harada, M., Horai, T., Ishino, H., Ito, S., Koshio, Y., Kitagawa, H., Ma, W., Piplani, N., Sakai, S., Kuno, Y., Barr, G., Barrow, D., Cook, L., Goldsack, A., Samani, S., Simpson, C., Wark, D., Nova, F., Boschi, T., Di Lodovico, F., Migenda, J., Sedgwick, S. Molina, Taani, M., Zsoldos, S., Yang, J. Y., Jenkins, S. J., Malek, M., McElwee, J. M., Stone, O., Thiesse, M. D., Thompson, L. F., Okazawa, H., Kim, S. B., Yu, I., Nishijima, K., Koshiba, M., Nakajima, K. Iwamoto Y., Ogawa, N., Yokoyama, M., Martens, K., Vagins, M. R., Izumiyama, S., Kuze, M., Tanaka, M., Yoshida, T., Inomoto, M., Ishitsuka, M., Ito, H., Matsumoto, R., Ohta, K., Shinoki, M., Martin, J. F., Tanaka, H. A., Towstego, T., Akutsu, R., Hartz, M., Konaka, A., de Perio, P., Prouse, N. W., Chen, S., Xu, B. D., Posiadala-Zezula, M., Hadley, D., Richards, B., Jamieson, B., Walker, J., Minamino, A., Pintaudi, G., Sano, S., Sasaki, R., Ichikawa, A. K., and Nakamura, K. D.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment
Abstract: The Super-Kamiokande detector can be used to search for neutrinos in time coincidence with gravitational waves detected by the LIGO-Virgo Collaboration (LVC). Both low-energy ($7-100$ MeV) and high-energy ($0.1-10^5$ GeV) samples were analyzed in order to cover a very wide neutrino spectrum. Follow-ups of 36 (out of 39) gravitational waves reported in the GWTC-2 catalog were examined; no significant excess above the background was observed, with 10 (24) observed neutrinos compared with 4.8 (25.0) expected events in the high-energy (low-energy) samples. A statistical approach was used to compute the significance of potential coincidences. For each observation, p-values were estimated using neutrino direction and LVC sky map ; the most significant event (GW190602_175927) is associated with a post-trial p-value of $7.8\%$ ($1.4\sigma$). Additionally, flux limits were computed independently for each sample and by combining the samples. The energy emitted as neutrinos by the identified gravitational wave sources was constrained, both for given flavors and for all-flavors assuming equipartition between the different flavors, independently for each trigger and by combining sources of the same nature., Comment: 16 pages, 5 figures. v2: adding corrections from The Astrophysical Journal review
Published: 2021
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49. First T2K measurement of transverse kinematic imbalance in the muon-neutrino charged-current single-$\pi^+$ production channel containing at least one proton

Author: Abe, K., Akhlaq, N., Akutsu, R., Ali, A., Alt, C., Andreopoulos, C., Antonova, M., Aoki, S., Arihara, T., Asada, Y., Ashida, Y., Atkin, E. T., Awataguchi, Y., Barker, G. J., Barr, G., Barrow, D., Batkiewicz-Kwasniak, M., Beloshapkin, A., Bench, F., Berardi, V., Berns, L., Bhadra, S., Blanchet, A., Blondel, A., Bolognesi, S., Bonus, T., Bourguille, B., Boyd, S. B., Bravar, A., Berguño, D. Bravo, Bronner, C., Bron, S., Bubak, A., Avanzini, M. Buizza, Cao, S., Cartwright, S. L., Catanesi, M. G., Cervera, A., Cherdack, D., Christodoulou, G., Cicerchia, M., Coleman, J., Collazuol, G., Cook, L., Coplowe, D., Cudd, A., De Rosa, G., Dealtry, T., Delogu, C. C., Dennis, S. R., Densham, C., Dergacheva, A., Di Lodovico, F., Dolan, S., Douqa, D., Doyle, T. A., Dumarchez, J., Dunne, P., Eguchi, A., Eklund, L., Emery-Schrenk, S., Ereditato, A., Finch, A. J., Fiorillo, G., Francois, C., Friend, M., Fujii, Y., Fukuda, R., Fukuda, Y., Fusshoeller, K., Giganti, C., Gonin, M., Gorin, A., Grassi, M., Guigue, M., Hadley, D. R., Hamacher-Baumann, P., Harris, D. A., Hartz, M., Hasegawa, T., Hassani, S., Hastings, N. C., Hayato, Y., Hiramoto, A., Hogan, M., Holeczek, J., Van, N. T. Hong, Honjo, T., Iacob, F., Ichikawa, A. K., Ikeda, M., Ishida, T., Ishitsuka, M., Iwamoto, K., Izmaylov, A., Izumi, N., Jakkapu, M., Jamieson, B., Jenkins, S. J., Jesús-Valls, C., Jonsson, P., Jung, C. K., Jurj, P. B., Kabirnezhad, M., Kakuno, H., Kameda, J., Kasetti, S. P., Kataoka, Y., Katayama, Y., Katori, T., Kearns, E., Khabibullin, M., Khotjantsev, A., Kikawa, T., Kikutani, H., King, S., Kisiel, J., Kobata, T., Kobayashi, T., Koch, L., Konaka, A., Kormos, L. L., Koshio, Y., Kostin, A., Kowalik, K., Kudenko, Y., Kuribayashi, S., Kurjata, R., Kutter, T., Kuze, M., Labarga, L., Lagoda, J., Lamoureux, M., Last, D., Laveder, M., Lawe, M., Litchfield, R. P., Liu, S. L., Longhin, A., Ludovici, L., Lu, X., Lux, T., Machado, L. N., Magaletti, L., Mahn, K., Malek, M., Manly, S., Maret, L., Marino, A. D., Marti-Magro, L., Maruyama, T., Matsubara, T., Matsushita, K., Mauger, C., Mavrokoridis, K., Mazzucato, E., McCauley, N., McElwee, J., McFarland, K. S., McGrew, C., Mefodiev, A., Mezzetto, M., Minamino, A., Mineev, O., Mine, S., Miura, M., Bueno, L. Molina, Moriyama, S., Mueller, Th. A., Munteanu, L., Nagai, Y., Nakadaira, T., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, K., Nakano, Y., Nakayama, S., Nakaya, T., Nakayoshi, K., Naseby, C. E. R., Ngoc, T. V., Nguyen, V. Q., Niewczas, K., Nishimura, Y., Noah, E., Nonnenmacher, T. S., Nova, F., Nowak, J., Nugent, J. C., O'Keeffe, H. M., O'Sullivan, L., Odagawa, T., Ogawa, T., Okada, R., Okumura, K., Okusawa, T., Owen, R. A., Oyama, Y., Palladino, V., Paolone, V., Pari, M., Parker, W. C., Parsa, S., Pasternak, J., Pavin, M., Payne, D., Penn, G. C., Pershey, D., Pickering, L., Pidcott, C., Pintaudi, G., Pistillo, C., Popov, B., Porwit, K., Posiadala-Zezula, M., Quilain, B., Radermacher, T., Radicioni, E., Radics, B., Ratoff, P. N., Riccio, C., Rondio, E., Roth, S., Rubbia, A., Ruggeri, A. C., Ruggles, C., Rychter, A., Sakashita, K., Sánchez, F., Santucci, G., Schloesser, C. M., Scholberg, K., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shaikhiev, A., Shaykina, A., Shiozawa, M., Shorrock, W., Shvartsman, A., Skwarczynski, K., Smy, M., Sobczyk, J. T., Sobel, H., Soler, F. J. P., Sonoda, Y., Spina, R., Suvorov, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sztuc, A. A., Tada, M., Tajima, M., Takeda, A., Takeuchi, Y., Tanaka, H. K., Tanihara, Y., Tani, M., Teshima, N., Thompson, L. F., Toki, W., Touramanis, C., Towstego, T., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Vagins, M., Valder, S., Vargas, D., Vasseur, G., Vilela, C., Vinning, W. G. S., Vladisavljevic, T., Wachala, T., Walker, J., Walsh, J. G., Wang, Y., Wan, L., Wark, D., Wascko, M. O., Weber, A., Wendell, R., Wilking, M. J., Wilkinson, C., Wilson, J. R., Wood, K., Wret, C., Xia, J., Xu, Y. -h., Yamamoto, K., Yanagisawa, C., Yang, G., Yano, T., Yasutome, K., Yershov, N., Yokoyama, M., Yoshida, T., Yoshimoto, Y., Yu, M., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Ziembicki, M., Zito, M., and Zsoldos, S.
Subjects: High Energy Physics - Experiment
Abstract: This paper reports the first T2K measurement of the transverse kinematic imbalance in the single-$\pi^+$ production channel of neutrino interactions. We measure the differential cross sections in the muon-neutrino charged-current interaction on hydrocarbon with a single $\pi^+$ and at least one proton in the final state, at the ND280 off-axis near detector of the T2K experiment. The extracted cross sections are compared to the predictions from different neutrino-nucleus interaction event generators. Overall, the results show a preference for models which have a more realistic treatment of nuclear medium effects including the initial nuclear state and final-state interactions.
Published: 2021
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50. Choice modelling in the age of machine learning -- discussion paper

Author: Van Cranenburgh, S., Wang, S., Vij, A., Pereira, F., and Walker, J.
Subjects: Economics - Econometrics, Computer Science - Machine Learning
Abstract: Since its inception, the choice modelling field has been dominated by theory-driven modelling approaches. Machine learning offers an alternative data-driven approach for modelling choice behaviour and is increasingly drawing interest in our field. Cross-pollination of machine learning models, techniques and practices could help overcome problems and limitations encountered in the current theory-driven modelling paradigm, such as subjective labour-intensive search processes for model selection, and the inability to work with text and image data. However, despite the potential benefits of using the advances of machine learning to improve choice modelling practices, the choice modelling field has been hesitant to embrace machine learning. This discussion paper aims to consolidate knowledge on the use of machine learning models, techniques and practices for choice modelling, and discuss their potential. Thereby, we hope not only to make the case that further integration of machine learning in choice modelling is beneficial, but also to further facilitate it. To this end, we clarify the similarities and differences between the two modelling paradigms; we review the use of machine learning for choice modelling; and we explore areas of opportunities for embracing machine learning models and techniques to improve our practices. To conclude this discussion paper, we put forward a set of research questions which must be addressed to better understand if and how machine learning can benefit choice modelling., Comment: 40 pages, 2 tables, 0 figures
Published: 2021
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