1. Incidence and risk factors of post-phototherapy neonatal rebound hyperbilirubinemia
- Author
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Eman Abdel Ghany Abdel Ghany, Walaa Alsharany Aboelhamed, Shahinaz Gamal Eldin Ibrahim, and Ismail Mohamed Elhawary
- Subjects
Male ,China ,medicine.medical_specialty ,Bilirubin ,Risk Assessment ,Severity of Illness Index ,Gastroenterology ,Statistics, Nonparametric ,Cohort Studies ,Sepsis ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Recurrence ,Intensive Care Units, Neonatal ,030225 pediatrics ,Internal medicine ,Severity of illness ,medicine ,Humans ,Prospective Studies ,030212 general & internal medicine ,Prospective cohort study ,Chi-Square Distribution ,business.industry ,Incidence ,Incidence (epidemiology) ,Infant, Newborn ,Phototherapy ,medicine.disease ,Low birth weight ,chemistry ,Pediatrics, Perinatology and Child Health ,Female ,Hyperbilirubinemia, Neonatal ,medicine.symptom ,business ,Chi-squared distribution ,Follow-Up Studies ,Cohort study - Abstract
To determine the incidence and risk factors of post-phototherapy rebound hyperbilirubinemia because data about bilirubin rebound in neonates are lacking and few studies have concerned this condition. A prospective observational study was conducted on 500 neonates with indirect hyperbilirubinemia who were treated according to standard guidelines. Total serum bilirubin (TSB) was measured at 24–36 h after phototherapy; significant bilirubin rebound (SBR) is considered as increasing TSB that needs reinstitution of phototherapy. A total of 124 (24.9%) neonates developed SBR with TSB increased by 3.4 (2.4–11.2) mg/dL after stopping phototherapy. Multiple logistic regression model revealed the following significant risk factors for rebound: low birth weight (B = 1.3, P
- Published
- 2018