1. Relationship between supernormal sectors of retinal nerve fibre layer and axial length in normal eyes
- Author
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Wakako Yoshinaga, Taiji Sakamoto, Kumiko Nakao, Yuya Kii, Takehiro Yamashita, Toshifumi Yamashita, and Minoru Tanaka
- Subjects
Adult ,Male ,Retinal Ganglion Cells ,medicine.medical_specialty ,genetic structures ,Optic Disk ,Nerve fibre layer ,Glaucoma ,Spectral domain ,Sensitivity and Specificity ,Young Adult ,chemistry.chemical_compound ,Nerve Fibers ,Predictive Value of Tests ,Ophthalmology ,Myopia ,medicine ,Humans ,False Positive Reactions ,Low Tension Glaucoma ,Prospective Studies ,Intraocular Pressure ,health care economics and organizations ,Aged ,business.industry ,Reproducibility of Results ,Retinal ,General Medicine ,Axial length ,medicine.disease ,Healthy Volunteers ,eye diseases ,Normative database ,Axial Length, Eye ,Cross-Sectional Studies ,medicine.anatomical_structure ,chemistry ,Female ,sense organs ,business ,Tomography, Optical Coherence ,Optic disc - Abstract
Purpose To determine the effect of the axial length on the supernormal and false-positive sectors of the peripapillary retinal nerve fibre layer (RNFL) in healthy eyes using the normative database embedded in a spectral domain optical coherence tomographic (SD-OCT) instrument. Methods This was a prospective, observational cross -sectional study. The right eyes of 126 healthy young volunteers were studied. The RNFL thickness was measured by SD-OCT in twelve 30-degree sectors (clock hours) around the optic disc. The sectors whose RNFL thickness was 95% probability level were labelled as supernormal sectors. The relationships between the axial length and rates of supernormal and false-positive sectors were investigated. Results A longer axial length was significantly associated with an increase in the rates of supernormal thickness in sector 8 (odds ratio, [OR], 1.494; p = 0.010) and sector 10 (OR, 1.529; p = 0.008). The supernormal sectors were mainly located in the temporal region. A longer axial length was significantly associated with a higher rates of false positives in sector 5 (OR, 1.789; p = 0.017), sector 6 (OR, 2.305; p
- Published
- 2014
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