Search

Your search keyword '"Wahjudi TD"' showing total 1 results
Start Over Author "Wahjudi TD"

Refine your results

1 results on '"Wahjudi TD"'

1. Multicentric dermatofibrosarcoma protuberans in a child with severe combined immunodeficiency due to adenosine deaminase deficiency.

Author

Wahjudi TD, Kutzner H, Bleeke M, and Hoeger PH

Subjects
Adenosine Deaminase, Agammaglobulinemia, Child, Child, Preschool, Humans, Male, Dermatofibrosarcoma diagnosis, Severe Combined Immunodeficiency complications, Severe Combined Immunodeficiency diagnosis, Severe Combined Immunodeficiency therapy, Skin Neoplasms complications, Skin Neoplasms diagnosis
Abstract

We report the case of a 4-year-old boy, post-human stem cell transplantation for severe combined immunodeficiency (SCID) due to adenosine deaminase deficiency (ADA), who developed multiple dermatofibrosarcoma protuberans (DFSP). We hypothesize a role for chimerism leading to accumulation of toxic metabolites which can cause DNA strand breaks and inhibit lymphocyte activation. Patients with ADA-SCID should remain under lifelong dermatologic surveillance as DFSP lesions can be quite inconspicuous., (© 2021 Wiley Periodicals LLC.)

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results