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Resumo Fundamento Existem dados limitados sobre a evolução clínica de lesões coronarianas não tratadas de acordo com sua gravidade funcional no mundo real. Objetivo Este estudo teve como objetivo avaliar os resultados clínicos de até 5 anos em pacientes com lesões revascularizadas com reserva de fluxo fracionada (FFR) ≤ 0,8 e em pacientes com lesões não revascularizadas com FFR > 0,8. Métodos A avaliação pelo FFR foi realizada em 218 pacientes seguidos por até 5 anos. Os participantes foram classificados com base na FFR no grupo isquêmico (≤ 0,8, grupo intervenção, n = 55), no grupo FFR normal-baixa (> 0,8-0,9, n = 91) e no grupo FFR normal-alta (> 0,9, n = 72). O desfecho primário foram eventos cardíacos adversos maiores (ECAMs), um composto de morte, infarto do miocárdio e necessidade de nova revascularização. O nível de significância adotado neste estudo foi alfa = 0,05; deste modo, resultados com valores de p < 0,05 foram considerados estatisticamente significativos. Resultados A maioria dos participantes era do sexo masculino (62,8%) com média de idade de 64,1 anos. Diabetes estava presente em 27%. À angiografia coronariana, a gravidade da estenose avaliada foi de 62%, 56,4% e 54,3% nos grupos isquêmico, FFR normal-baixa e FFR normal-alta, respectivamente (p < 0,05). O período médio de acompanhamento foi de 3,5 anos. A incidência ECAM foi de 25,5%, 13,2% e 11,1%, respectivamente (p = 0,037). Não houve diferença na incidência de ECAM entre os grupos FFR normal-baixa e FFR normal-alta (p = NS). Conclusão Pacientes com FFR indicativa de isquemia apresentaram piores desfechos quando comparados aos dos grupos não isquêmicos. Entre os grupos que apresentaram valores de FFR considerados normal-baixo e normal-alto, não houve diferença na incidência de eventos. Há necessidade de estudos de longo prazo e com grande número de pacientes para melhor avaliar os desfechos cardiovasculares em pacientes portadores de estenose coronariana moderada com valores de FFR entre 0,8 e 1,0. Abstract Background There are limited real-world data on the clinical course of untreated coronary lesions according to their functional severity. Objective To evaluate the 5-year clinical outcomes of patients with revascularized lesions with fractional flow reserve (FFR) ≤ 0.8 and patients with non-revascularized lesions with FFR > 0.8. Methods The FFR assessment was performed in 218 patients followed for up to 5 years. Participants were classified based on FFR into ischemia group (≤ 0.8, intervention group, n = 55), low-normal FFR group (> 0.8-0.9, n = 91), and high-normal FFR group (> 0.9, n = 72). The primary endpoint was major adverse cardiac events (MACEs), a composite of death, myocardial infarction, and need for repeat revascularization. The significance level was set at 0.05; therefore, results with a p-value < 0.05 were considered statistically significant. Results Most patients were male (62.8%) with a mean age of 64.1 years. Diabetes was present in 27%. On coronary angiography, the severity of stenosis was 62% in the ischemia group, 56.4% in the low-normal FFR group, and 54.3% in the high-normal FFR group (p

This article reveals a study presenting the initial version of the technological development and the evaluation of an app for mobile devices that assists in making the data collection, analysis, evaluation and monitoring of healthy school cafeterias. The app was developed in stages, including definition of the research aims, evaluation by specialists, adaptation, practical application in 27 school cafeterias and evaluation of usability, perception and acceptance by users. The app is available for the Android operating system and it is divided into three parts: characterization of the profile of the school cafeteria; health risk consideration; and characteristics of foods offered. The evaluation revealed a satisfactory usability regarding the criteria of effectiveness, efficiency, and user satisfaction. Among the main benefits of using the app, are the greater agility of data collection, processing and analysis, it is easy to use, the standardization of procedures and its economic advantage concerning the environmental sustainability. Future work will involve improving its functionality and making a public version available. Este artículo revela un estudio que tiene como objetivo presentar la versión inicial del desarrollo tecnológico y evaluación de una app móvil que ayuda la recopilación de datos, el análisis, la la evaluación y seguimiento de cantinas escolares saludables. El desarrollo de la aplicación se realizó por etapas, con la definición de los ejes de investigación, evaluación por parte de especialistas, adecuación, aplicación práctica en 27 cantinas escolares y evaluación de usabilidad, percepción y aceptación por parte de los usuarios finales. La aplicación, desarrollada para ser ejecutada en el sistema operativo Android, se divide en tres partes: caracterización del perfil de la cantina escolar; evaluación de riesgos para la salud; y características de los alimentos comercializados. La aplicación tuvo usabilidad satisfactoria conforme a los criterios de efectividad, eficiencia y satisfacción del usuario. Entre los principales beneficios, se destacan la mayor agilidad de recopilación, procesamiento y análisis de datos, facilidad de uso, estandarización de procedimientos y la ventaja económica de contribuir para la sustentabilidad ambiental. El trabajo futuro implicará mejorar las funcionalidades suyas y hacer que una versión pública sea disponible. Este artigo revela um estudo que tem por objetivo apresentar a versão inicial do desenvolvimento tecnológico e a avaliação de um aplicativo móvel que auxilia a coleta de dados, análise, avaliação e o monitoramento das cantinas escolares saudáveis. O desenvolvimento do aplicativo aconteceu em etapas, com a definição dos eixos de investigação, avaliação por especialistas, adaptação, aplicação prática em 27 cantinas escolares e avaliação da usabilidade, percepção e aceitação pelos usuários finais. O aplicativo, desenvolvido para o sistema operacional Android, é dividido em três partes: caracterização do perfil da cantina escolar; avaliação do risco sanitário; e características dos alimentos comercializados. Ele apresentou uma usabilidade satisfatória no que diz respeito aos critérios de efetividade, eficiência e satisfação do usuário. Entre os principais benefícios, destacam-se a maior agilidade de coleta, processamento e análise de dados, a facilidade de uso, a padronização dos procedimentos e vantagens econômicas de contribuir para a sustentabilidade ambiental. Trabalhos futuros envolverão melhoria de suas funcionalidades e disponibilização de uma versão pública.

Background. Zabrotes subfasciatus (Boh., 1833) (Coleoptera: Chrysomelidae: Bruchinae), is considered one of the most important pest of stored beans. Objective. This study reports the possible toxicity and repellence of powders prepared from eight plant species against the Mexican bean weevil in two formulations (dry powder and sachets). Methodology. A 10 ˟ 2 factorial design (10 species ˟ 2 formulations) with 8 repetitions in a completely randomized design was employed. Pots with no powder were used as a negative control, and a pyrethroid insecticide [K-Obiol® 2 DP (deltamethrin, 0.5 g a.i. ton-1)] was applied as a positive control. Results. A mixture of powdered Chenopodium ambrosioides L., Ruta graveolens L. and Mentha pulegium L. added to bean grains was confirmed to be toxic to Z. subfasciatus adults with promising grain protector properties. C. ambrosioides powder had the same effect when in a sachet. A mixture of powdered R. graveolens, M. pulegium and C. ambrosioides with the beans inhibited weevil oviposition. The same effect was achieved for M. pulegium and C. ambrosioides in sachets. A mixture of powdered C. ambrosioides, M. pulegium, R. officinalis and R. graveolens repelled Z. subfasciatus adults from bean grains. Implications. This is the first report of using botanical derivatives by means of sachets or dry formulations, a pre-commercial purpose for aromatic plants with insecticidal/repellent activities. Conclusions. Sachets containing powdered C. ambrosioides and M. pulegium efficiently controlled the Mexican bean weevil in stored beans and constitute an useful tools for domestic grain stock or post-harvest management of organic grains.

Objetivos: Descrever os resultados do teste do reflexo vermelho em recém-nascidos a termo.Identificar fatores associados ao resultado do teste do reflexo vermelho e comparar o tempode internac ̧ão entre pacientes com teste do reflexo vermelho duvidoso e normal.Métodos: Estudo transversal descritivo dos resultados do teste do reflexo vermelho feito emmaternidade de hospital terciário entre 2014 e 2018. Foi ainda feito estudo de caso-controleaninhado para pesquisa de variáveis antropométricas, gestacionais e neonatais associadas aoresultado do teste do reflexo vermelho.Resultados: Foram identificados 121 casos de teste do reflexo vermelho duvidoso em 11.833recém-nascidos. Foram confirmadas 16 alterac ̧ões, 4 consideradas graves: 2 casos de glaucomacongênito, um de catarata e um de coloboma. As médias de peso de nascimento (p = 0,04), com-primento (p = 0,03) e perímetro cefálico (p = 0,02) foram menores nos pacientes com teste doreflexo vermelho duvidoso, entretanto sem um tamanho de efeito relevante (d = -0,21; -0,22e -0,25; respectivamente). A proporc ̧ão de pacientes brancos, pardos e negros foi estatisti-camente diferente entre os grupos (p < 0,001), com maior chance de resultado duvidoso parapardos (OR = 2,22) e negros (OR = 3,37) em comparac ̧ão a brancos. O teste do reflexo vermelhoduvidoso levou a um aumento no tempo de internac ̧ão de 62 para 82 horas (p < 0,001).Conclusões: O teste do reflexo vermelho foi capaz de identificar 4 alterac ̧ões graves em 11.833recém-nascidos (0,03%). Nos 121 recém-nascidos em que o teste do reflexo vermelho foi classi-ficado como duvidoso, houve aumento de 20 horas no tempo de internac ̧ão hospitalar, porém seconfirmou alterac ̧ão grave em apenas 3,3% deles. Diferenc ̧as no reflexo vermelho entre brancos,pardos e negros devem ser consideradas. Objectives: Describe the results of the red reflex test in full-term newborns, as well as identifyfactors associated with red reflex test outcome and compare hospital length of stay betweenpatients with inconclusive and normal red reflex test results.Methods: Descriptive cross-sectional study of the results of the red reflex test performed in atertiary hospital maternity unit between 2014 and 2018. A nested case-control study was alsoperformed to search for anthropometric, gestational, and neonatal variables associated withthe outcome of the red reflex test.Results: There were121 identified cases of inconclusive red reflex test in 11,833 newborns.Sixteen alterations were confirmed, four considered severe: two cases of congenital glaucoma,one of cataract, and one of coloboma. Mean birth weight (p = 0.04), length (p = 0.03), and headcircumference (p = 0.02) were lower in patients with inconclusive red reflex test; however with-out a relevant effect size (d = −0.21, −0.22, and −0.25, respectively).The proportion of white,mixed-race, and black patients was significantly different between the groups (p < 0.001), witha higher chance of inconclusive results in mixed-race (OR = 2.22) and black (OR = 3.37) patientswhen compared to whites. An inconclusive red reflex test led to an increase in hospital lengthof stay from 62 to 82 hours (p < 0.001). Conclusions: The red reflex test was able to identify four severe alterations in 11,833 newborns(0.03%). In the 121 newborns in which the red reflex test was classified as inconclusive, therewas a 20-hour increase in the hospital length of stay, but a severe alteration was confirmedin only 3.3% of them. Differences in red reflex between white, mixed-race, and black patientsshould be considered.

Esta tese aborda a questão da sustentabilidade nas políticas de desenvolvimento urbano propostas pelo governo municipal para a área do Baixo 4º Distrito de Porto Alegre. Na busca pela verificação do grau de sustentabilidade contido nessas políticas, o trabalho analisa o plano de revitalização urbana e reconversão econômica proposto pelo Masterplan do 4º Distrito de Porto Alegre, de 2016. A tese se desenvolve em duas partes: uma teóricoconceitual, na qual são discutidos o processo de restruturação urbana contemporâneo e os preceitos do desenvolvimento sustentável; e outra de estudo de caso, analisando a inclusão das dimensões conceituais do desenvolvimento sustentável nas políticas públicas nacionais e nos planos governamentais para a área do Baixo 4º Distrito de Porto Alegre. Nas últimas três décadas, uma série de planos e projetos foram elaborados pela prefeitura de Porto Alegre visando a reestruturação urbana do seu antigo distrito industrial. Examinando as circunstâncias que levaram à concepção dessas propostas, é possível identificar três períodos distintos: período Tecnológico, de 1995 à 2004; período Copa do Mundo, de 2006 à 2009; e período Consorciado, de 2013 à 2016. Todos reflexos de posições político-ideológicas e mercadológicas marcadas por uma nova dinâmica econômica e espacial, pautada na parceria público-privado e no discurso sustentável. Para avaliar o grau de real sustentabilidade contido nessas políticas, foi introduzido o Modelo de Verificação Emelianoff-Acselrad (MVEA), estruturado a partir de uma base tecno-material, e outra socioambiental. Esta pesquisa permitiu identificar o uso de uma narrativa ambientalizada, onde o termo sustentabilidade passa a ser usado como uma ferramenta de marketing governamental e empresarial para conferir credibilidade a qualquer projeto urbano. O MVEA se propõe a servir de parâmetro tanto para a formulação como para a avaliação de planos, projetos e políticas públicas urbanas que tenham como objetivo um desenvolvimento plenamente sustentável. This thesis addresses the issue of sustainability in the urban development policies proposed by the municipal government of Porto Alegre, Brazil, for the area known as Lower 4th District (Baixo 4º Distrito). In order to verify the degree of sustainability contained in these policies, this research analyses the urban revitalization and economic reconversion plan proposed in the 2016 Masterplan do 4º Distrito de Porto Alegre. The thesis has two parts: a theoreticalconceptual part, in which the contemporary process of urban restructuring and the precepts of sustainable development are discussed; and another, the case study, which analyses the inclusion of the conceptual dimensions of sustainable development in national public policies and local plans for the Lower 4th District area. In the last three decades, a number of plans and projects have been introduced by the local government with the aim of restructuring its former industrial district. By examining the circumstances that led to these proposals, it is possible to identify three distinct periods: the Technological period 1995 to 2004; the World Cup period 2006 to 2009; and the Consortium period 2013 to 2016. Each of these reflects a distinct political ideology and real estate marketing position, driven by a new economic and spatial dynamic, based on public-private partnership and sustainability narratives. In order to assess the degree of real sustainability contained in these policies, the Emelianoff-Acselrad Verification Model (MVEA) was introduced, which uses prioritised techno-material and socio-environmental set of criteria. This research made it possible to identify the use of an environmentalized narrative, where the term sustainability is now used as a government and business marketing tool to lend credibility to any urban project. The MVEA is intended to serve as a benchmark for both the formulation and evaluation of plans, projects and public policies aiming for genuine sustainable development.

Resumo Objetivos Avaliar a contribuição dos alimentos ultraprocessados no consumo alimentar de crianças pertencentes à área de abrangência de uma unidade básica de saúde e os fatores associados. Método Estudo transversal com amostra de conveniência de 204 crianças, entre dois a 10 anos, no Sul do Brasil. O consumo alimentar das crianças foi obtido por meio do Recordatório Alimentar de 24 horas e, posteriormente, os alimentos foram classificados em minimamente processados, processados para culinária e ultraprocessados. Um questionário semiestruturado foi aplicado para a coleta das variáveis sociodemográficas e antropométricas. O excesso de peso das crianças foi definido por meio do escore Z > 2 para menores de cinco anos e Z > +1 para entre cinco e 10 anos segundo o Índice de Massa Corporal para idade. Resultados A frequência de excesso de peso foi de 34% (IC95%: 28% a 41%). O consumo médio de energia foi de 1.672,3 kcal/dia, 47% (IC95%: 45% a 49%) provenientes dos ultraprocessados. No modelo de regressão linear múltipla, a escolaridade materna (r = 0,23; p = 0,001) e a idade da criança (r = 0,40; p < 0,001) foram associados à maior contribuição percentual dos ultraprocessados na alimentação (R = 0,42; p < 0,001). Adicionalmente foi observada uma tendência linear significativa para maior consumo de ultraprocessados quando os dados foram estratificados pela idade da criança e nível de escolaridade materna (p < 0,001). Conclusões A contribuição dos ultraprocessados é expressiva na alimentação infantil e a idade da criança mostrou-se como fator associado mais importante para o consumo desses produtos. Abstract Objectives To evaluate the contribution of ultra-processed food (UPF) on the dietary consumption of children treated at a Basic Health Unit and the associated factors. Methodology Cross-sectional study carried out with a convenience sample of 204 children, aged 2-10 years old, in Southern Brazil. Children's food intake was assessed using a 24-h recall questionnaire. Food items were classified as minimally processed, processed for culinary use, and ultra-processed. A semi-structured questionnaire was applied to collect socio-demographic and anthropometric variables. Overweight in children was classified using a Z score >2 for children younger than 5 and Z score >+1 for those aged between 5 and 10 years, using the body mass index for age. Results Overweight frequency was 34% (95% CI: 28-41%). Mean energy consumption was 1672.3 kcal/day, with 47% (95% CI: 45-49%) coming from ultra-processed food. In the multiple linear regression model, maternal education (r = 0.23; p = 0.001) and child age (r = 0.40; p < 0.001) were factors associated with a greater percentage of UPF in the diet (r = 0.42; p < 0.001). Additionally, a statistically significant trend for higher UPF consumption was observed when data were stratified by child age and maternal educational level (p < 0.001). Conclusions The contribution of UPF is significant in children's diets and age appears to be an important factor for the consumption of such products.

Made available in DSpace on 2018-11-26T17:52:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-06-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) The common bean Phaseolus vulgaris L (Fabaceae) is an important vegetable protein source and constitutes a significant part of the diet in many tropical countries. The Mexican bean weevil Zabrotes subfasciatus (Boheman) (Coleoptera: Bruchidae) is one of the main pests affecting stored beans: it causes extensive qualitative and quantitative grain loss. We investigated the bioactivity of the essential oils extracted from Chenopodium ambrosioides L (CA-EO), Ocimum gratissimum L (OG-EO), and Schinus terebinthifolius Raddi (ST-EO) against Z. subfasciatus. After 12-h treatment, CA-EO and OG-EO at 20.0 mu L/L of air killed 100% Z subfasciatus, whereas ST-EO at 100.0 mu L/L of air afforded 100% 1 subfasciatus mortality after 24 h. CA-EO provided the lowest 24 h LD50 (0.8 mu L/L of air) and displayed efficient repellent activity against Z subfasciatus. Our results demonstrate that CA-EO is a potentially economical and environmentally friendly alternative to manage Z. subfasciatus in stored beans. (C) 2018 Elsevier Ltd. All rights reserved. Univ Estadual Paulista, Fac Ciencias Agron, Dept Protecao Vegetal, BR-18610307 Botucatu, SP, Brazil Univ Fed Bahia, Inst Quim, Dept Quim Organ, BR-40170115 Salvador, BA, Brazil Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Quim, BR-14040900 Ribeirao Preto, SP, Brazil Univ Estadual Paulista, Fac Ciencias Agron, Dept Protecao Vegetal, BR-18610307 Botucatu, SP, Brazil FAPESP: 2007/54241-8 CNPq: 303892/2016-1

Despite several pharmacological applications of Rosmarinus officinalis L. (Lamiaceae), studies on its analgesic and anti-inflammatory properties have been scarce.The aim of this work was to use in vivo models to evaluate the analgesic and anti-inflammatory activities of the aqueous extracts obtained from leaves (AEL) and stems (AES) of Rosmarinus officinalis, as well as its isolated compound--rosmarinic acid (RA). We also prepared and assessed the acetyl ester derivative of RA.The analgesic activity was evaluated using abdominal constriction and formalin tests. For the evaluation of the anti-inflammatory effects, carrageenin-induced paw edema in rats were used. The extracts were used at doses of 100, 200 and 400 mg kg⁻¹ compounds were tested at 10, 20 and 40 mg kg⁻¹.Orally administered AEL, AES and RA were not significantly active at any of the doses tested during the abdominal constriction test; the acetyl ester derivative of RA displayed significant analgesic activity. In the carrageenin-induced paw edema assay, the acetyl derivative of RA at all the tested doses produced significant anti-inflammatory effects and reduced the number of paw licks in the second phase of the formalin test.The results suggest that the analgesic effects of the acetyl derivative of RA operate via a peripheral-mediated mechanism. The acetyl ester derivative of RA is potentially applicable as a new lead compound for the management of pain and inflammation.

The essential oil of Rosmarinus officinalis L. (rosemary) was obtained by hydro-distillation and analysed by gas chromatography-mass spectrometry. Sixty-two constituents were identified, representing 98.06% of the total oil content. Oxygenated monoterpenes were the predominant components. The rosemary oil was characterized as having prominent (> 5%) contents of camphor (18.9%), verbenone (11.3%), α-pinene (9.6%), β-myrcene (8.6%), 1,8-cineole (8.0%), and β-caryophyllene (5.1%). The antimicrobial activity of the oil as well as of its major constituents was tested against the following microorganisms: Streptococcus mutans, Streptococcus mitis, Streptococcus sanguinis, Streptococcus salivarius, Streptococcus sobrinus, and Enterococcus faecalis, which are potentially responsible for the formation of dental caries in humans. The microdilution method was used for determination of the minimum inhibitory concentration (MIC) during evaluation of the antibacterial activity. The essential oil displayed low activity against the selected microorganisms. In the present study, the pure major compounds were more active than the essential oil. Among all the microorganisms tested, the pathogen S. mitis was the most susceptible and E. faecalis was the most resistant to the evaluated samples. This is the first report on antimicrobial activity of the major components of rosemary oil against oral pathogens.

The in vitro inhibitory activity of crude EtOH/H2O extracts from the leaves and stems of Rosmarinus officinalis L. was evaluated against the following microorganisms responsible for initiating dental caries: Streptococcus mutans, S. salivarius, S. sobrinus, S. mitis, S. sanguinis, and Enterococcus faecalis. Minimum inhibitory concentrations (MIC) were determined with the broth microdilution method. The bioassay-guided fractionation of the leaf extract, which displayed the higher antibacterial activity than the stem extract, led to the identification of carnosic acid (2) and carnosol (3) as the major compounds in the fraction displaying the highest activity, as identified by HPLC analysis. Rosmarinic acid (1), detected in another fraction, did not display any activity against the selected microorganisms. HPLC Analysis revealed the presence of low amounts of ursolic acid (4) and oleanolic acid (5) in the obtained fractions. The results suggest that the antimicrobial activity of the extract from the leaves of R. officinalis may be ascribed mainly to the action of 2 and 3.

Despite new contributions on sexuality and perversion in Freudian theory, a considerable number of analysts are still attached to attitudes of condemnation and prejudice regarding the field of perversion. In being so, they contradict the Freudian statements that they use as their anchors. Not even the “return to Freud” proposed by Lacan could dissipate this misunderstanding. Bernardes WS Veruteilung, Verleugnung, Teilung. Dasnicht – / wissen – / wollen von Perversion Trotz der neuen Beitrage uber Sexualitat und Perversion seitens der Freudianischen Theorie, hangt noch eine betrachtliche Anzahl von Analytikern an Haltungen von Verurteilung und Vorurteil im Feld der Perversion. Dadurch widersprechen Sie den Freudianischen Aussagen, welche sie als ihre Anker verwenden. Selbst das “Zuruck zu Freud”, welches Lacan vorgeschlagen hat, konnte dieses Misverstandnis nicht zerstreuen. Bernardes WS. Condenacion, division. El no-querer-saber sobre perversion. A pesar de las nuevas contribuciones sobre sexuali...

Introduction: Contrast induced nephropathy is the third most prevalent preventable cause of acute kidney injury in hospitalized patients. It defined as an absolute increase in serum creatinine ≥ 0.5 mg/dL and relative ≥ 25% increase. Objective: We studied the risk factors to intravenous injection contrast nephropathy after computed tomography. Methods: We studied 400 patients prospectively. Results: The incidence of contrast induced nephropathy, with an absolute or a relative increase were 4.0% and 13.9%, respectively. Diabetes and cardiac failure were independent risk factors for CIN a relative increase de serum creatinine (O.R.: 3.5 [95% CI: 1.92-6.36], p < 0.01, 2.61 [95% CI: 1.14-6.03%], p < 0.05, respectively). Conclusions: We showed association between uses of intravenous injection contrast after computed tomography with acute injury renal, notably with diabetes and heart failure. Introdução: Nefropatia induzida por contraste é a terceira causa de lesão renal aguda em pacientes hospitalizados. Ela é definida como: um aumento absoluto da creatinina sérica ≥ 0,5 mg/dL e relativo em ≥ 25%. Objetivo: Nós estudamos os fatores de risco associados à nefropatia do contraste após tomografia computadorizada. Métodos: Analisamos prospectivamente 400 pacientes submetidos ao contraste endovenoso na tomografia computadorizada. Resultados: A incidência de nefropatia por contraste variou de 4 a 13,9%, conforme o critério de aumento da creatinina sérica. Diabetes e insuficiência cardíaca foram associados significativamente no aumento absoluto da creatinina sérica (O.R.: 3,5 [95% CI: 1,92-6,36], p < 0,01, 2,61 [95% CI: 1,14-6,03%], p < 0,05, respectivamente). Conclusão: Encontramos uma relação direta da infusão de contraste endovenoso na tomografia computadorizada e injúria renal, notadamente com diabetes e insuficiência cardíaca.