434 results on '"Wagner, Karl G."'
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2. Multivariate Analysis of Solubility Parameters for Drug-Polymer Miscibility Assessment in Preparing Raloxifene Hydrochloride Amorphous Solid Dispersions
3. Powder dosing within continuous manufacturing: A lean approach for gravimetric dosing configuration and equipment selection
4. In vivo predictive dissolution of the lipophilic phytochemicals trans-resveratrol, coenzyme Q10 and quercetin
5. High loading of lipophilic compounds in mesoporous silica for improved solubility and dissolution performance
6. Phase homogeneity in ternary amorphous solid dispersions and its impact on solubility, dissolution and supersaturation – Influence of processing and hydroxypropyl cellulose grade
7. Highly protein-loaded melt extrudates produced by small-scale ram and twin-screw extrusion - evaluation of extrusion process design on protein stability by experimental and numerical approaches
8. Direct Tableting on a Continuous Manufacturing Line—Impact of Mixing Parameters, Material Densities, and Drug Load on Subsequent Process Parameters and Tablet Quality
9. Boost of solubility and supersaturation of celecoxib via synergistic interactions of methacrylic acid-ethyl acrylate copolymer (1:1) and hydroxypropyl cellulose in ternary amorphous solid dispersions
10. Drugs for neglected tropical diseases: availability of age-appropriate oral formulations for young children
11. Polymer-mediated drug supersaturation – A spotlight on the interplay between phase-separated amorphous drug colloids and dissolved molecules
12. Compression of amorphous solid dispersions prepared by hot-melt extrusion, spray drying and vacuum drum drying
13. In vitro and in vivo assessment of hydroxypropyl cellulose as functional additive for enabling formulations containing itraconazole
14. Influence of high pressure compaction on solubility and intrinsic dissolution of ibuprofen binary mixtures employing standard excipients
15. Evaluation of Printability of Pva-Based Tablets from Powder and Assessment of Critical Rheological Parameters
16. ASD Formation Prior to Material Characterization as Key Parameter for Accurate Measurements and Subsequent Process Simulation for Hot-Melt Extrusion
17. Transformation of Ritonavir Nanocrystal Suspensions into a Redispersible Drug Product via Vacuum Drum Drying
18. A novel approach to determine the granule density of milled ribbons using multi-stage air classification combined with dynamic image analysis
19. Influence of shellac on the improvement of solubility and supersaturation of loratadine amorphous solid dispersion using a new grade of HPMC
20. Compression behaviour of granules produced via twin-screw melt granulation: Effect of initial particle size on granulation efficiency
21. Assessment of Abrasion-Induced Visual Defects in Twin Screw Wet Granulation Using Wall Friction Measurements
22. Handling Challenging Powders in Tableting Operations
23. Immediate-Release Formulations Produced via Twin-Screw Melt Granulation: Systematic Evaluation of the Addition of Disintegrants
24. Evaluation of Printability of PVA-Based Tablets from Powder and Assessment of Critical Rheological Parameters.
25. Mesoporous Silica as an Alternative Vehicle to Overcome Solubility Limitations.
26. Influence of Particle Size and Drug Load on Amorphous Solid Dispersions Containing pH-Dependent Soluble Polymers and the Weak Base Ketoconazole
27. Advanced In Vivo Prediction by Introducing Biphasic Dissolution Data into PBPK Models
28. Development and Performance of a Highly Sensitive Model Formulation Based on Torasemide to Enhance Hot-Melt Extrusion Process Understanding and Process Development
29. Team Approach: Timing of Operative Intervention in Multiply-Injured Patients
30. Amorphous Solid Dispersions Layered onto Pellets—An Alternative to Spray Drying?
31. Micro-Scale Vacuum Compression Molding as a Predictive Screening Tool of Protein Integrity for Potential Hot-Melt Extrusion Processes
32. Solubility Enhanced Formulation Approaches to Overcome Oral Delivery Obstacles of PROTACs
33. Pharmacokinetics and Pharmacodynamics (PK/PD) of Corallopyronin A against Methicillin-Resistant Staphylococcus aureus
34. Hot Melt Extrusion for Sustained Protein Release: Matrix Erosion and In Vitro Release of PLGA-Based Implants
35. Bioanalytical Workflow for Qualitative and Quantitative Assessment of Hot-Melt Extruded Lysozyme Formulations
36. Pharmacology and early ADMET data of corallopyronin A, a natural product with macrofilaricidal anti-wolbachial activity in filarial nematodes
37. In vivo predictive mini-scale dissolution for weak bases: Advantages of pH-shift in combination with an absorptive compartment
38. Numerical simulation of hot-melt extrusion processes for amorphous solid dispersions using model-based melt viscosity
39. From benchtop to pilot scale–experimental study and computational assessment of a hot-melt extrusion scale-up of a solid dispersion of dipyridamole and copovidone
40. In Vitro–In Vivo Relationship in Mini-Scale—Enabling Formulations of Corallopyronin A
41. Itraconazole Nanosuspensions via Dual Centrifugation Media Milling: Impact of Formulation and Process Parameters on Particle Size and Solid-State Conversion as Well as Storage Stability
42. Rational Development of Solid Dispersions via Hot-Melt Extrusion Using Screening, Material Characterization, and Numeric Simulation Tools
43. Corallopyronin A: antimicrobial discovery to preclinical development
44. Predicting melt rheology for hot-melt extrusion by means of a simple Tg-measurement
45. Compression Modulus and Apparent Density of Polymeric Excipients during Compression—Impact on Tabletability
46. Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders† †Electronic supplementary information (ESI) available. See DOI: 10.1039/d0sc00167h
47. Design, synthesis, and characterization of PROTACs targeting the androgen receptor in prostate and lung cancer models
48. Impact of Vertical Blender Unit Parameters on Subsequent Process Parameters and Tablet Properties in a Continuous Direct Compression Line
49. Corallopyronin A: antimicrobial discovery to preclinical development
50. Laser triangulation as a fast and reliable method for determining ribbon solid fraction; focus on accuracy, precision, and measurement time
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