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12 results on '"Waga, Toshiaki"'

3. Fast‐to‐slow shift of muscle fiber‐type composition by dietary apple polyphenols in rats: Impact of the low‐dose supplementation

Author

Mizunoya, Wataru, primary, Okamoto, Shinpei, additional, Miyahara, Hideo, additional, Akahoshi, Mariko, additional, Suzuki, Takahiro, additional, Do, Mai‐Khoi Q., additional, Ohtsubo, Hideaki, additional, Komiya, Yusuke, additional, Qahar, Mulan, additional, Waga, Toshiaki, additional, Nakazato, Koichi, additional, Ikeuchi, Yoshihide, additional, Anderson, Judy E., additional, and Tatsumi, Ryuichi, additional

Published
2016
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4. Improvement of Endurance Based on Muscle Fiber-Type Composition by Treatment with Dietary Apple Polyphenols in Rats

Author

Mizunoya, Wataru, primary, Miyahara, Hideo, additional, Okamoto, Shinpei, additional, Akahoshi, Mariko, additional, Suzuki, Takahiro, additional, Do, Mai-Khoi Q., additional, Ohtsubo, Hideaki, additional, Komiya, Yusuke, additional, Lan, Mu, additional, Waga, Toshiaki, additional, Iwata, Akira, additional, Nakazato, Koichi, additional, Ikeuchi, Yoshihide, additional, Anderson, Judy E., additional, and Tatsumi, Ryuichi, additional

Published
2015
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12. Fast-to-slow shift of muscle fiber-type composition by dietary apple polyphenols in rats: Impact of the low-dose supplementation.

Author

Mizunoya, Wataru, Okamoto, Shinpei, Miyahara, Hideo, Akahoshi, Mariko, Suzuki, Takahiro, Do, Mai‐Khoi Q., Ohtsubo, Hideaki, Komiya, Yusuke, Qahar, Mulan, Waga, Toshiaki, Nakazato, Koichi, Ikeuchi, Yoshihide, Anderson, Judy E., and Tatsumi, Ryuichi

Subjects
DIETARY supplements, RATS -- Food, POLYPHENOLS, COMPOSITION of apples, MYOSIN, MYOGLOBIN
Abstract

Our previous studies demonstrated that an 8-week intake of 5% (w/w) apple polyphenol (APP) in the diet improves muscle endurance of young-adult rats. In order to identify a lower limit of the dietary contribution of APP to the effect, the experiments were designed for lower-dose supplementation (8-week feeding of 0.5% APP in AIN-93G diet) to 12-week-old male Sprague-Dawley rats. Results clearly showed that the 0.5% APP diet significantly up-regulates slower myosin-heavy-chain (MyHC) isoform ratios (IIx and IIa relative to total MyHC) and myoglobin expression in lower hind-limb muscles examined ( P < 0.05). There was a trend to increased fatigue resistance detected from measurements of relative isometric plantar-flexion force torque generated by a stimulus train delivered to the tibial nerve ( F(98, 1372) = 1.246, P = 0.0574). Importantly, there was no significant difference in the animal body-phenotypes or locomotor activity shown as total moving distance in light and dark periods. Therefore, the present study encourages the notion that even low APP-intake may increase the proportions of fatigue-resistant myofibers, and has promise as a strategy for modifying performance in human sports and improving function in age-related muscle atrophy. [ABSTRACT FROM AUTHOR]

Published
2017
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