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17 results on '"Wade, Minal"'

3. Impact of anemia on outcome of HIV-infected pediatric patients: A prospective observational study

Author

Bhaisara, Baraturam Bhagrati, Gajre, Mona, Manglani, Mamta, Wade, Minal, and Sharma, Sujata

Subjects
lcsh:Public aspects of medicine, HIV, Original Article, lcsh:RA1-1270, Hemoglobin, CD4 count
Abstract

Introduction: Anemia has been widely reported to predict a poorer prognosis for HIV-infected patients, both in terms of progression to AIDS and in survival. This study aimed to determine the etiology of anemia and its immunological correlation in HIV-infected children. Materials and Methods: Four hundred and eighty-nine HIV-infected children were screened, of which 86 HIV-infected children with anemia were enrolled. Standard WHO definitions were used for anemia, HIV staging, and growth parameters. Chi-square test, t-tests, and univariate and multivariate logistic regression analyses were used to analyze the data. Results: Anemia was present in 17.58% (86/489) of HIV-infected children, including 84.6% with moderate anemia, 11.5% with severe anemia, and 2.32% with mild anemia. The mean hemoglobin (Hb) among patients with CD4 count 350 cell/mm3 (P = 0.02). Children with severe immunological stage had a significantly lower mean Hb (adjusted estimate: −1.61, 95% confidence interval: −2.65, −0.56) compared to those who had normal immune status. No statistically significant differences in mean Hb at baseline when compared to various demographic and clinical characteristics were observed in unadjusted and adjusted regression models. Conclusion: Hb is an easy and inexpensive tool to measure and can be used for monitoring disease progression in a resource-limited setting.

Published
2019

16. Assessment of safety and immunogenicity of two different lots of diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenzae type b vaccine manufactured using small and large scale manufacturing process

Author

Sharma, Hitt J., primary, Patil, Vishwanath D., additional, Lalwani, Sanjay K., additional, Manglani, Mamta V., additional, Ravichandran, Latha, additional, Kapre, Subhash V., additional, Jadhav, Suresh S., additional, Parekh, Sameer S., additional, Ashtagi, Girija, additional, Malshe, Nandini, additional, Palkar, Sonali, additional, Wade, Minal, additional, Arunprasath, T.K., additional, Kumar, Dinesh, additional, and Shewale, Sunil D., additional

Published
2012
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17. Juvenile Hyaline Fibromatosis- A Rare Autosomal Recessive Disease.

Author

Kalgaonkar PS, Wade M, Warke C, Makhecha M, and Khare M

Abstract

Systemic hyalinosis is inherited as an autosomal recessive disease. It may also be referred to as Fibromatosis hyalinica multiplex juvenilis and Murray-Puretic-Drescher syndrome. A four and a half-year-old female child presented with multiple soft tissue swellings involving the nose, orbital ridges, ears, bony prominences of the ulna and tibia and the parietal and occipital prominence and had gum hypertrophy. The diagnosis of this rare condition was based upon clinicopathological correlation, wherein the histopathological examination of cutaneous lesions reveals accumulation of hyaline material with fibroblast in the dermis. A multidisciplinary approach helped in correct diagnosis, management and in providing counseling for the parents. The child's parents were counseled about the surgical excision of the lesion; however, the parents opted for non-surgical conservative management.

Published
2017
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