1. Morbus Castleman: Auswertung von 338 Fällen
- Author
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Martin Heller, Wacker Hh, Brinkmann G, Elfeldt Rj, and H. Schwarzenberg
- Subjects
medicine.medical_specialty ,Pathology ,business.industry ,Mediastinum ,Mean age ,Hyaline vascular type ,Benign lymphoma ,Gastroenterology ,Axilla ,medicine.anatomical_structure ,Internal medicine ,Epidemiology ,medicine ,Radiology, Nuclear Medicine and imaging ,Large group ,business - Abstract
PURPOSE To evaluate a large group of patients with Castleman's tumours (Castleman's disease = MC) with regard to age, sex and tumour localisation. PATIENTS AND METHODS 338 cases of MC were evaluated. All cases were registered by the Lymphknotenregister of the German Society of Pathology, Kiel. RESULTS 292 MC of the hyaline vascular type (MC-HV) and 46 of the plasma cell type (MC-PC) were found, 259 (76.6%) in nodal and 79 (23.4%) in extranodal localisation. Main nodal localisation were the neck (25.5%) and the axilla (12.8%). The mediastinum was involved in only 6.2%. There was a slight preference of female (56%) compared to male (44%). Patients with MC-PC (mean age: 50 +/- 16.9 years) were significantly older (p < 0.001) than patients with MC-HV (mean age: 39 +/- 18.9 years). CONCLUSIONS The main localisation of MC is the neck. MC-HV is more common than MC-PC. There is a slight preference for women. Mean age of patients with MC-PC is approximate 10 years higher than for MC-HV.
- Published
- 1995
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