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Your search keyword '"Wachter, B. de"' showing total 12 results
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12 results on '"Wachter, B. de"'

1. Effect of oxygen and salt on haemolymph oxygen binding in the brine shrimp Artemia franciscana

Author

Wachter, B. de, Abbeele, J. van den, and Wolf, G.

Subjects
Shrimps -- Research, Ligand binding (Biochemistry) -- Research, Oxygen -- Analysis, Biological sciences
Abstract

The oxygen-binding properties of haemolymph in the brine shrimp Artemia franciscana increases with oxygen partial pressure up to normoxic values. A further increase in pressure has no effect. The proportional change of three different hemoglobins in the haemolymphs is responsible for an increase in binding. Oxygen binding property is not influenced by major salts, pH and the metal-binding ligand EGTA.

Published
1994

2. GLRB allelic variation associated with agoraphobic cognitions, increased startle response and fear network activation: a potential neurogenetic pathway to panic disorder

Author

Deckert, J., Weber, H., Villmann, C., Lonsdorf, T.B., Richter, J., Andreatta, M., Arias-Vasquez, A., Hommers, L., Kent, L., Schartner, C., Cichon, S., Wolf, C., Schaefer, N., Collenberg, C.R. von, Wachter, B. de, Blum, R., Schumann, D., Scharfenort, R., Schumacher, J., Forstner, A.J., Baumann, C., Schiele, M.A., Notzon, S., Zwanzger, P., Janzing, J.G., Galesloot, T.E., Kiemeney, L.A.L.M., Gajewska, A., Glotzbach-Schoon, E., Muhlberger, A., Alpers, G., Fydrich, T., Fehm, L., Gerlach, A.L., Kircher, T., Lang, T., Strohle, A., Arolt, V., Wittchen, H.U., Kalisch, R., Buchel, C., Hamm, A., Nothen, M.M., Romanos, M., Domschke, K., Pauli, P., Reif, A., Deckert, J., Weber, H., Villmann, C., Lonsdorf, T.B., Richter, J., Andreatta, M., Arias-Vasquez, A., Hommers, L., Kent, L., Schartner, C., Cichon, S., Wolf, C., Schaefer, N., Collenberg, C.R. von, Wachter, B. de, Blum, R., Schumann, D., Scharfenort, R., Schumacher, J., Forstner, A.J., Baumann, C., Schiele, M.A., Notzon, S., Zwanzger, P., Janzing, J.G., Galesloot, T.E., Kiemeney, L.A.L.M., Gajewska, A., Glotzbach-Schoon, E., Muhlberger, A., Alpers, G., Fydrich, T., Fehm, L., Gerlach, A.L., Kircher, T., Lang, T., Strohle, A., Arolt, V., Wittchen, H.U., Kalisch, R., Buchel, C., Hamm, A., Nothen, M.M., Romanos, M., Domschke, K., Pauli, P., and Reif, A.

Abstract

Contains fulltext : 177350.pdf (publisher's version ) (Closed access), The molecular genetics of panic disorder (PD) with and without agoraphobia (AG) are still largely unknown and progress is hampered by small sample sizes. We therefore performed a genome-wide association study with a dimensional, PD/AG-related anxiety phenotype based on the Agoraphobia Cognition Questionnaire (ACQ) in a sample of 1370 healthy German volunteers of the CRC TRR58 MEGA study wave 1. A genome-wide significant association was found between ACQ and single non-coding nucleotide variants of the GLRB gene (rs78726293, P=3.3 x 10-8; rs191260602, P=3.9 x 10-8). We followed up on this finding in a larger dimensional ACQ sample (N=2547) and in independent samples with a dichotomous AG phenotype based on the Symptoms Checklist (SCL-90; N=3845) and a case-control sample with the categorical phenotype PD/AG (Ncombined =1012) obtaining highly significant P-values also for GLRB single-nucleotide variants rs17035816 (P=3.8 x 10-4) and rs7688285 (P=7.6 x 10-5). GLRB gene expression was found to be modulated by rs7688285 in brain tissue, as well as cell culture. Analyses of intermediate PD/AG phenotypes demonstrated increased startle reflex and increased fear network, as well as general sensory activation by GLRB risk gene variants rs78726293, rs191260602, rs17035816 and rs7688285. Partial Glrb knockout mice demonstrated an agoraphobic phenotype. In conjunction with the clinical observation that rare coding GLRB gene mutations are associated with the neurological disorder hyperekplexia characterized by a generalized startle reaction and agoraphobic behavior, our data provide evidence that non-coding, although functional GLRB gene polymorphisms may predispose to PD by increasing startle response and agoraphobic cognitions.

Published
2017

4. Sparsame elektrische Antriebe

Author

Keulenaer, H. de, Belmans, R., Blaustein, E., Chapman, D., Almeida, A. de, Wachter, B. de, Radgen, P., and Publica

Published
2004

7. Climate induced temperature effects on growth performance, fecundity and recruitment in marine fish: developing a hypothesis for cause and effect relationships in Atlantic cod (Gadus morhua) and common eelpout (Zoarces viviparus).

Author

Pörtner, Hans-Otto, Berdal, B., Blust, R., Brix, O., Colosimo, A., Wachter, B. de, Giuliani, A., Johansen, T., Fischer, T., Knust, Rainer, Lannig, Gisela, Naevdal, G., Nedenes, A., Nyhammer, G., Sartoris, Franz-Josef, Serendero, I., Sirabella, P., Thorkildsen, S., Zakhartsev, Maxim, Pörtner, Hans-Otto, Berdal, B., Blust, R., Brix, O., Colosimo, A., Wachter, B. de, Giuliani, A., Johansen, T., Fischer, T., Knust, Rainer, Lannig, Gisela, Naevdal, G., Nedenes, A., Nyhammer, G., Sartoris, Franz-Josef, Serendero, I., Sirabella, P., Thorkildsen, S., and Zakhartsev, Maxim

Published
2001

9. Growth performance, fecundity and recruitment in marine fishs in Atlantic cod (Gadus morhua) and common eelpout (Zoarces viviparus).

Author

Pörtner, Hans-Otto, Berdal, B., Blust, R., Brix, O., Colosimo, A., Wachter, B. de, Giuliani, A., Johansen, T., Fischer, T., Knust, Rainer, Naevdal, G., Nedenes, A., Nyhammer, G., Sartoris, Franz-Josef, Serendero, I., Sirabella, P., Thorkildsen, S., Zakhartsev, Maxim, Pörtner, Hans-Otto, Berdal, B., Blust, R., Brix, O., Colosimo, A., Wachter, B. de, Giuliani, A., Johansen, T., Fischer, T., Knust, Rainer, Naevdal, G., Nedenes, A., Nyhammer, G., Sartoris, Franz-Josef, Serendero, I., Sirabella, P., Thorkildsen, S., and Zakhartsev, Maxim

Published
2000

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