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Under a diagnostic schema that used cervical conization liberally for evaluating women with abnormal Papanicolaou smears, 82 pregnant patients underwent conization. Fifteen had significant morbidity related to cervical bleeding. The uncorrected perinatal mortality was 44.1/1000. Sixty-one cone biopsies, performed before colposcopy was introduced into the schema, uncovered 2 cases of previously undiagnosed invasive carcinoma. Among 21 patients who underwent colposcopy before conization, 1 case of microinvasive carcinoma was diagnosed. During the study, 15 patients with frankly invasive carcinoma were identified, 9 by punch biopsy of a gross lesion, 2 by cone biopsy without prior colposcopy, and 4 by colposcopically directed punch biopsy. As a result of the review, the diagnostic schema has been changed so that biopsy is used less often on pregnant patients.

Gold, the favorite metal of mankind, formed a part of many formulas of the early alchemists. Years of experimentation were spent in investigating various elements designated by cabalistic signs, in the hope of producing this precious metal synthetically. It also formed an important ingredient in the various "elixirs of life." Paracelsus1 stated that the mingling of the rose-colored blood from the lion and the glue from the eagle forms the philosopher's tincture for which men without number have sought.Dalton2 interpreted this mystic preparation as follows:We should remember that "lion" is one of the cabalistic synonyms for gold, and the "eagle" one of those for tin. If gold be dissolved in nitro-muriatic acid, evaporated and heated and the product dissolved in water, it forms a solution of the terchloride of gold. This was probably the alchemist's "rose colored blood from the lion." On the other hand, protochloride

During the past year or more I have been particularly struck by the divergence of opinion expressed by my dermatologic confrères in New York respecting the value of liquid air in dermatology. In regard to its efficacy in some affections, there seems to be a general unanimity of opinion, while in others our opinions are strikingly at variance. This is the history of almost every new therapeutic agent, especially if it is a little out of the ordinary, and appears to be due, on the one hand, to a difference in the interpretation of its real powers and therapeutic properties and, on the other, to variations in the technic employed.This is the position in which we find the x-ray to-day; there are few who understand it, hence the great difference in the effects produced and the results obtained. Sabouraud can use it in ringworm with a precision and uniform