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132 results on '"WATSON, DANIEL J."'

3. Dual Allegiance in Military Healthcare: US Air Force and Defense Health Agency Convergence

Author

Watson, Daniel J., Paige, Christopher, and Robb, Douglas. J.

Subjects
Air forces -- Military aspects, United States. Department of Defense, United States. Joint Chiefs of Staff, United States. Air Force. Medical Service, United States. Air Force
Abstract

Recent congressionally directed changes gave the Defense Health Agency authority, direction, and control of military treatment facilities. But limited authorities resulted in the agency's pursuit of capacity, typically measured via medical productivity standards. The Air Force maintains command authorities to organize, train, equip, and provide capabilities, including medical, to the combatant commander. These dual authorities converge at the military treatment facility, producing a conflict between capacity and capability. Tension, already present due to the dual nature of the mission to provide support and healthcare delivery to beneficiaries, has increased and threatens the Air Force's ability to medically support combat operations, generating risk to the operational mission. With the increasing likelihood and stakes of armed conflict, senior leaders can mitigate the risk to the operational mission by decreasing the tension and risk at Air Force MTFs., The October 2022 US National Security Strategy identified the People's Republic of China (PRC) as 'America's most consequential geopolitical challenge.' (1) Framed as great power competition, the narrative in the [...]

Published
2023

11. Development of Transition Metal-Mediated Cyclopropanation Reactions

Author

DelMonte, Albert J., Dowdy, Eric D., Watson, Daniel J., Brown, John M., editor, Fürstner, Alois, editor, Hofmann, Peter, editor, van Koten, Gerard, editor, Kündig, E. Peter, editor, Reetz, Manfred, editor, Dixneuf, Pierre H., editor, Hegedus, Louis S., editor, Knochel, Paul, editor, Murai, Shinji, editor, and Abe, A., editor

Published
2004
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26. Critical Issues in Modelling Lymph Node Physiology

Author

Grebennikov, Dmitry, primary, van Loon, Raoul, additional, Novkovic, Mario, additional, Onder, Lucas, additional, Savinkov, Rostislav, additional, Sazonov, Igor, additional, Tretyakova, Rufina, additional, Watson, Daniel J., additional, and Bocharov, Gennady, additional

Published
2016
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27. Critical Issues in Modelling Lymph Node Physiology.

Author

Grebennikov, Dmitry, van Loon, Raoul, Novkovic, Mario, Onder, Lucas, Savinkov, Rostislav, Sazonov, Igor, Tretyakova, Rufina, Watson, Daniel J., and Bocharov, Gennady

Subjects
LYMPH nodes, B cells, T cells, MASS transfer, BONE marrow
Abstract

In this study, we discuss critical issues in modelling the structure and function of lymph nodes (LNs), with emphasis on how LN physiology is related to its multi-scale structural organization. In addition to macroscopic domains such as B-cell follicles and the T cell zone, there are vascular networks which play a key role in the delivery of information to the inner parts of the LN, i.e., the conduit and blood microvascular networks. We propose object-oriented computational algorithms to model the 3D geometry of the fibroblastic reticular cell (FRC) network and the microvasculature. Assuming that a conduit cylinder is densely packed with collagen fibers, the computational flow study predicted that the diffusion should be a dominating process in mass transport than convective flow. The geometry models are used to analyze the lymph flow properties through the conduit network in unperturbed- and damaged states of the LN. The analysis predicts that elimination of up to 60%-90% of edges is required to stop the lymph flux. This result suggests a high degree of functional robustness of the network. [ABSTRACT FROM AUTHOR]

Published
2017
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