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Objective: To establish an anatomical relationship between the nasopharyngeal cavity volume and facial shape using cone-beam computed tomography (CBCT). Methodology: In this study, 90 CBCT outcomes were analyzed to determine if the facial shape influences the morphology of the nasopharynx. Using InVivoDental software for the reconstruction of cephalometric images, facial patterns (dolichofacial, mesofacial, and brachyfacial patterns) ascertained from cephalometric measurements that indicate the growth direction, were assessed. Subsequently, ITK-SNAP 2.1.4 software was used to delimit the nasopharynx; the upper region was the hard palate bone and the lower region was the epiglottis at the base of the skull. The total volume of the nasopharynx was measured twice by the same examiner at two different time points. The results obtained were evaluated using Kendall rank correlation coefficient and the Kruskal-Wallis test. Results: To determine the reliability of the evaluations, the Kendall rank correlation coefficient was used at two different time points and no discrepancy was observed. A p value <0.0001 was obtained for all three groups. To determine the relationship between the facial shape and nasopharyngeal cavity volume variables, the Kruskal-Wallis test was applied, and a p value of 0.8311 was obtained, which indicated no statistically significant difference between the variables in any of the three groups analyzed. Conclusion: No statistically significant difference was observed between the groups while trying to determine the relationship between the facial shape and nasopharyngeal cavity volume (p = 0.8311). This result suggested that regardless of the facial shape, the airway volume does not show significant variations. [ABSTRACT FROM AUTHOR]

The gingival recession is a common clinical condition that brings aesthetic inconvenient and sensitivity, beyond of functional problems. Looking for a result that meets both aesthetically as functionally, many techniques has been proposed to achieve the radicular overlap, among them the coronal slide from the patch. The Patch Coronally Positioned consist in the displacement of the gingival tissue from the area more apical in a direction to the area that will be treated. A technique of simple pediculated graft, that besides can be restricted it an indication, because it has some limitations, can show good results when it's well indicated. Due to the lack of predictability, treat a gingival recession is considered a big challenge for professionals from odontology and, in the case that is reported in this paper, it was objectified by the authors describe a clinical case where it was realized a radicular overlap through the coronal displacement in a Miller Class II, in the esthetic reestablishment and dental function. [ABSTRACT FROM AUTHOR]

Objectives: The aim of this study was to investigate the healing activity of andiroba (Carapa guianensis Aubl.) against oral mucositis (OM) induced by 5-fluorouracil in golden Syrian hamsters.Materials and methods: A total of 122 animals were randomized and divided into six groups: andiroba oil 100%, andiroba oil 10%, andiroba oil 10% refined, no treatment group, all n = 28; and negative control (NC) and cyclophosphamide (CPA) groups, both n = 5. OM was induced by intraperitoneal administration of 60 mg/kg 5-FU on days 0, 5 and 10 followed by mechanical trauma on the oral mucosa on days 1 and 2. From day 1 to day 15, the animals of the andiroba group were treated three times a day. On days 4, 8, 12 and 15, the mucosa was photographed and removed for clinical and histopathological analysis. The bone marrow of the femur was removed and the micronucleus test was performed to evaluate the cytotoxicity and genotoxicity. The data were subjected to analysis of variance, followed by the Tukey and Bonferroni test.Results: Treatment with 100% andiroba oil reduced the degree of OM compared to that reported in the other groups (p < 0.05). Andiroba oil at both concentrations was not cytotoxic, but treatment with 100% andiroba oil showed a genotoxic potential (p < 0.001).Conclusions: Frequent administration of andiroba oil accelerated the healing process in an experimental model of 5-fluorouracil-induced OM. However, the genotoxicity of andiroba in other cell systems and under other conditions are being tested.Clinical relevance: The use of andiroba in topical form may be associated with reduced intensity of OM. Seek therapeutic alternatives to minimize the pain and suffering that these side effects cause cancer patients is an important scientific step. [ABSTRACT FROM AUTHOR]

Purpose: To evaluate the presence of calcifications in the internal carotid artery (ICA) in cone-beam computed tomography (CBCT), and to verify the association of these findings with sex, age, dental condition, and risk factors associated with vascular disorders.Methods: The CBCT scans used in this study were obtained from the database of a private dental clinic requested for the planning of rehabilitation with dental implants. The selection criteria were patients aged 40 years and above. Out of a pool of 1176 CBCT examinations, a total of 284 scans of adult patients were evaluated by two blinded observers. Data were collected from patients' medical records.Results: ICA calcifications were present in 63.0% of the examinations. Most calcifications were in the intracranial pathway (166). Despite being present in a smaller number 57 (C1), extracranial calcifications were more severe. Spearman's ρ coefficients (rS) indicated that the number of missing teeth was directly associated with the presence of calcifications (p = 0.042) and severity (p = 0.020). The age variable also had a direct relationship with the presence of calcifications (p ≤ 0.0001), increasing its frequency and severity over the years. In addition, hypertension (p = 0.036) and use of antihypertensive drugs (p = 0.015) were directly associated.Conclusions: There is a high occurrence of ICA calcifications in CBCT as incidental findings in adult patients, and it is directly associated with age, number of missing teeth and hypertension. [ABSTRACT FROM AUTHOR]