11 results on '"W.F. Bodmer"'
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2. Introduction
- Author
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E. Solomon and W.F. Bodmer
- Subjects
Genetics ,Molecular Biology ,Genetics (clinical) - Published
- 1991
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3. A sensitive micro-immunoassay using β-galactosidase/ anti-β-galactosidase complexes
- Author
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H. Durbin and W.F. Bodmer
- Subjects
Antigen-Antibody Complex ,medicine.drug_class ,Immunology ,Monoclonal antibody ,Mice ,Antigen ,Escherichia coli ,medicine ,Animals ,Immunology and Allergy ,Immunoassay ,chemistry.chemical_classification ,Mice, Inbred BALB C ,biology ,medicine.diagnostic_test ,Microchemistry ,Antibodies, Monoclonal ,beta-Galactosidase ,Molecular biology ,Enzyme assay ,Galactosidases ,Enzyme ,chemistry ,Monoclonal ,biology.protein ,Antibody - Abstract
This paper describes a new sensitive microELISA based on enzyme/anti-enzyme complexes following an unlabelled antibody bridging step. beta-Galactosidase/anti-beta-galactosidase complexes were made using a monoclonal antibody raised against bacterial (E. coli) beta-galactosidase and enzyme activity was quantified with a fluorogenic substrate. Because of its high sensitivity the assay is particularly suitable for the detection of limited amounts of antigen. One application illustrated is the analysis of Class I and Class II histocompatibility antigens on peripheral blood lymphocytes using 5000 cells/well in 60-well Terasaki or 96-well microtitre plates.
- Published
- 1987
- Full Text
- View/download PDF
4. Subject Index Vol. 16, 1976
- Author
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D.E. Wilson, P. Shaffer-Berman, E. Solomon, N. Shimizu, S. Goss, P. DeBona, A.G. Steinberg, R.M. Siervogel, A.S. Henderson, T.-S. Chan, J.E. Anderson, A.B. Deisseroth, J.A. Anderson, D. Weil, A.D. Merritt, M. Velivasakis, D. Cox, P. Meera Khan, K.M. Overton, G.B. Côté, E. Lovrien, J.A. Brown, S. Chen, C. Finaz, R.H. Schwartz, I.W. Craig, J. Courval, B. Olaisen, P. Teisberg, J.A. Robinson, P.L. Pearson, M.C. DuVal, N. Busby, M. Ray, T.P. Webb, R.H. Kennett, C.J. Chern, P.J. Davies, I. Schreuder, B. Kaiser McCaw, H. Wyandt, J. Mohr, A. Icén, K.E. Buckton, A.R. Dunn, A.W. Nienhuis, J.V. Higgins, R.G. Worton, P.J.L. Cook, G. Spowart, J.A. Norton, J.E. Noades, R.S. Kucherlapati, W.S. Volkers, T.B. Shows, H. Wang, R.A. Raeburn, Matthew Parks, R.E. Magenis, M. Bobrow, S. Hansen, H.M. Dick, S.H. Boyer, S.H. Hsu, Veronica van Heyningen, K.R.M. Pai, R.A. Fisher, D.P. Aden, C.A. Slaughter, A.B. Bijnen, R.D. Koler, S. Guttormsen, R. Sanger, D. Linder, F. Hecht, D. Bacon, R.B. Surana, P.L. Yu, L.A. Klobutcher, O. Smithies, T.T. Puck, D.A. Hopkinson, D. Warburton, D. Shaw, K. Berg, S.J. Goss, L.L.L. Wijnen, D.A. Meyers, A. Heiberg, T. Gedde-Dahl, E. Hackel, C. Cochet, J. Frézal, C.M. Giles, A.A. Biegel, I.P. Gormley, M. Smith, F.-T. Kao, P. Vuopio, B. Schacter, B. Clark, J.D. Minna, T.A. Tedesco, M.G. Brown, C.J. Glueck, K.G. Orkwiszewski, H. Skre, K. Hirschhorn, N. Van Cong, W.F. Bodmer, W.G. Burgerhout, B.A. Doppert, W. Bodmer, G. Skude, A. Boué, E.A. Jones, K.C. Atwood, S. McDonald, C.M. Croce, E. Eicher, E.S. Seravalli, R.C.P. Go, C.G. Palmer, E.B. Robson, K. Bender, D.A. Aitken, R.P. Creagan, W.F. Anderson, P.H. Gallimore, J.B. Dossetor, W. Putt, M. Lewis, V. Lewis, F.H. Ruddle, J. Ott, H. Eiberg, M. Rivas, T.H. Marshall, M.E. Hodes, K.D. Smith, P. Bowen, A.P.M. Jongsma, R. Bigley, N. Lea, G.F. Brooks, H. Kaita, L. Wisniewski, E.R. Giblett, H.E. Faber, R.C. Elston, P. Couillin, W.B. Bias, H. Koprowski, R. Rebourcet, C.T. Falk, M.T. Yu, L.J. Stevens, U. Francke, J.J. van Rood, G. Pontecorvo, P.E. Polani, D. Patterson, E.W. Lovrien, E.A. Nichols, J.L. Hamerton, D.P. Singal, J.K. McDougall, M.L. Rivas, T. Reber, B.H. Petersen, S. Povey, Erik Thorsby, G. Khoury, E. Tolley, W.R. Breg, T. Hassold, L. Kunkel, R.L. Eddy, L.L. Haley, J. Shuster, M.A. Ferguson-Smith, D.W. Buck, R.M. Denney, K. Lange, F.H. Allen, B.R. Migeon, P. Goodfellow, R. Kucherlapati, L.R. Weitkamp, J. de Grouchy, B.M. Turner, S.S. Wachtel, T. Mohandas, P.M. Conneally, M. Siniscalco, M.D. Poulik, R. Velez, A. Hershberg, B. Moore, G.C. Koo, V.M. Chapman, A. Westerveld, B. Hellkuhl, H.P. Klinger, D. Bootsma, K.K. Namboodiri, G. Wullems, O.J. Miller, P. Gold, P. Perry, P.J. McAlpine, P.A. Lalley, A. Brøgger, J. Schlaut, M.W. Thompson, A. de la Chapelle, B. Chown, A.G. Searle, I. Pagan-Charry, C. Jones, J. van der Horst, H. van Someren, K. Willecke, E. Johnston, J.H. Edwards, W.J. Mellman, K.-H. Grzeschik, S. Ohno, P. Teesdale, C.S.N. Lee, L. Wang, and V.S. Turner
- Subjects
Index (economics) ,Statistics ,Genetics ,Subject (documents) ,Biology ,Molecular Biology ,Genetics (clinical) - Published
- 1976
- Full Text
- View/download PDF
5. Contents, Vol. 14, 1975
- Author
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T. Gedde-Dahl, P.M Conneally, G.R. Douglas, J. Prosser, E. Grace, J.L. Hamerton, K.-H. Grzeschik, M.A. Ferguson-Smith, P.L. Pearson, G. Corneo, E.A. Nichols, G.J. Wullems, M. Bobrow, N.C. Sun, J.E. Syrett, J.K. McDougall, R. Rebourcet, J. Frézal, V.A. McKusick, F.H. Ruddle, W. Keijzer, A. Westerveld, T.G. Gedde-Dahl, R.M. Baker, R.C. Miller, F. Hecht, P. Goodfellow, B. Olaisen, J. Ott, A.J.J. Reuser, A. Vust, C.W.H. Partridge, D.R. Bolling, J. Fleming, S.E. Gardiner, P.J. McAlpine, D.M. Steffensen, E.R. Giblett, D. Kacian, E.M. Wurzer-Figurelli, R.S. Kucherlapati, T.B. Shows, K. Berg, H. Bosker, K.C. Atwood, M.C. Rattazzi, D.W. Buck, K.W. Jones, A.G.J.M. van der Linden, R.P. Clayton, J. German, W. Prensky, V. Niewczas-Late, D. Bergsma, C.M. Giles, D.A. Meyers, E.M. Eicher, D.S. Borgaonkar, D. Mutton, K.P. Glen, P.M. Ellis, K. Hirschhorn, E. Jones, S. Povey, A. Hoogeveen, J. van der Horst, J.J. van Rood, P.M. Price, B. Bengtsson, W.G. Burgerhout, C.C. Chang, L.R. Weitkamp, R.E. Giles, E. Magenis, H. van Someren, H.M.A. Beyersbergen van Henegouwen, R.A. Buckland, K. Willecke, U. Francke, D. Bootsma, C. Partridge, R. Kennett, E. Johnston, D.A. Hopkinson, A.E. Greene, O. Mutchinick, R.P. Creagan, R.S.K. Chaganti, L. Komarnicki, T. Mohandas, M. Fellous, K. Fenger, J.H. Edwards, G. Beckman, A.S. Henderson, M.L. Rivas, L. Beckman, W.R.T. Los, L.L. Coriell, I. Purdom, N. van Cong, P. Meera Khan, H.A. de Wit-Verbeek, G.B. Côté, A.R. Mitchell, Veronica van Heyningen, S.A. Sørensen, L. Wang, E. Solomon, J.A. Brown, W.S. Volkers, H. Galjaard, J.E. Anderson, C. Pangalos, A.P.M. Jongsma, R. Sanger, S.M. Elsevier, E. Lovrien, A.B. Bijnen, M.K. Fagerhol, J.A. Pierce, M. Lewis, E.H.Y. Chu, W.B. Bias, D. Weil, S. Chen, J. de Wit, C.G. Palmer, P.W. Teesdale, F.A. McMorris, G. Miller, A.D. Merritt, R.G. Davidson, J.R. Gosden, I. Schreuder, W.F. Bodmer, P.J.L. Cook, J.E. Gray, N. Busby, H. Kaita, R.C. Elston, Y.-S. Teng, S.M. Bowser Riley, R.A. Oosterbaan, P.L. Townes, E.B. Robson, H.J. Evans, L.E. Nijenhuis, and A. Hagemeijer
- Subjects
Botany ,Genetics ,Biology ,Molecular Biology ,Genetics (clinical) - Published
- 1975
- Full Text
- View/download PDF
6. References to the committee reports
- Author
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L.R. Weitkamp, J.E. Anderson, F.A. McMorris, L. Komarnicki, O. Mutchinick, S.M. Elsevier, T. Mohandas, J.L. Hamerton, G. Miller, J.R. Gosden, E. Lovrien, D.R. Bolling, J. Fleming, H.J. Evans, G.J. Wullems, J. Prosser, N.C. Sun, H. Bosker, K.C. Atwood, W. Keijzer, H.M.A. Beyersbergen van Henegouwen, A.B. Bijnen, M.K. Fagerhol, J. Ott, J. van der Horst, E. Grace, C.W.H. Partridge, R.C. Miller, Y.-S. Teng, P.J. McAlpine, J.E. Gray, J. de Wit, H. van Someren, K. Willecke, K. Hirschhorn, V. Niewczas-Late, T.B. Shows, D.A. Hopkinson, A.E. Greene, L. Beckman, J.A. Pierce, H.A. de Wit-Verbeek, P.W. Teesdale, R. Kennett, E. Johnston, R.E. Giles, G.B. Côté, P.L. Pearson, E. Magenis, A.G.J.M. van der Linden, M. Bobrow, V.A. McKusick, N. van Cong, J.H. Edwards, A.D. Merritt, P. Meera Khan, R.G. Davidson, P.L. Townes, I. Schreuder, S.A. Sørensen, K.W. Jones, J. Frézal, M.L. Rivas, E.B. Robson, D. Weil, A. Hoogeveen, R.A. Buckland, J.J. van Rood, K.-H. Grzeschik, E. Jones, E.A. Nichols, W.F. Bodmer, P.J.L. Cook, D.S. Borgaonkar, L. Wang, E. Solomon, B. Olaisen, K. Fenger, A.S. Henderson, A.J.J. Reuser, A. Vust, G. Beckman, E.M. Wurzer-Figurelli, J.E. Syrett, W.G. Burgerhout, C.C. Chang, D. Kacian, Veronica van Heyningen, S.E. Gardiner, A.R. Mitchell, W.B. Bias, C.M. Giles, S. Chen, F. Hecht, J.A. Brown, N. Busby, H. Kaita, C.G. Palmer, D.A. Meyers, R.C. Elston, T.G. Gedde-Dahl, R.M. Baker, A.P.M. Jongsma, K. Berg, R.S. Kucherlapati, L.E. Nijenhuis, I. Purdom, R. Sanger, R.P. Clayton, U. Francke, J.K. McDougall, J. German, P.M. Ellis, S.M. Bowser Riley, P.M. Price, M. Lewis, S. Povey, E.H.Y. Chu, R.A. Oosterbaan, L.L. Coriell, P. Goodfellow, D. Mutton, K.P. Glen, C. Partridge, R.S.K. Chaganti, D. Bootsma, M. Fellous, W. Prensky, W.R.T. Los, D.M. Steffensen, G. Corneo, D.W. Buck, E.M. Eicher, A. Westerveld, B. Bengtsson, M.C. Rattazzi, F.H. Ruddle, E.R. Giblett, W.S. Volkers, R.P. Creagan, T. Gedde-Dahl, P.M Conneally, G.R. Douglas, M.A. Ferguson-Smith, H. Galjaard, C. Pangalos, R. Rebourcet, D. Bergsma, and A. Hagemeijer
- Subjects
Genetics ,Library science ,Biology ,Bioinformatics ,Molecular Biology ,Genetics (clinical) - Published
- 1975
- Full Text
- View/download PDF
7. PARTICIPANTS
- Author
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MARIJA ALACEVIC, I. ALTOSAAR, L.J. ARCHER, K. AUNSTRUP, A.A. BAYEV, G. BERNARDI, G. BERTANI, J.H. BIRKNER, J. BIRNBAUM, F. BLASI, W.F. BODMER, R. BREATHNACH, F. BROWN, A. CAMPBELL, R. CAPE, A.R. CASHMORE, S. CHANG, T-Y CHOW, PATRICIA CLARKE, S.N. COHEN, J.D. COOMBES, P.E. CORNELIS, R.A. COX, R.K. CRAIG, J. DAVISON, V. DEBABOV, S.D. EHRLICH, I. FEDORCSAK, W. FIERS, MAGDALENA FIKUS, J.R.S. FINCHAM, S.W. FISHER, R.B. FLAVELL, I.I. FODOR, M. FRIED, A. FURUYA, W.J. GARTLAND, T. GEFFEN, E. GEISSLER, MARY-JANE GETHING, K.I. GIBSON, JACQUELINE GITS, W. GOEBEL, DONNA HARBER, D.O. HAINES, T.J.R. HARRIS, M. HASHMI, L. HATCH, G. HOLT, T. IINO, J. INGLE, I.S. JOHNSON, L. KAARIAINEN, SIR J. KENDREW, N.O. KIELDGAARD, H.F. KLEFENZ, M.A. KOCH, M. KOLOSOV, SIR HANS KORNBERG, E. LAING, B.W. LANGLEY, A.F. LANGLYKKE, ELEANOR LAWRENCE, R. LEWIN, H.W. LEWIS, B-C. LIN, A. LINDBERG, R.G. LLOYD, EBBA LUND, A.P. MACLENNAN, K. MARKOV, M. MARTIN, B.J. MIFLIN, DIANE J. MITCHELL, J.H. MORRIS, K. MURRAY, V.R. OVIATT, H. PANNEKOEK, W.J. PEACOCK, G.B. PETERSEN, V. PIRROTTA, R.H. PRITCHARD, O.W. PROZESKY, H.A. RAUE, M. RICHARDS, M.H. RICHMOND, R. RILEY, GILLIAN RITCHIE, F.R. ROLLESTON, W.C. RUSSELL, W.J. RUTTER, J. SAMBROOK, G.F. SAUNDERS, J.S. SCHELL, JANE K. SETLOW, V. SGARAMELLA, G. SHARPE, G. SIEWERT, MAXINE SINGER, ANNA MARIE SKALKA, K.G. SKRYABIN, D.A. SOUTHGATE, E. SPROTT, P. STARLINGER, H.D. STETTEN, MARJORIE STETTEN, M.G.P. STOKER, J. SUBAK-SHARPE, Y. SVERDLOV, W. SZYBALSKI, A. TALAVERA, S-T TAN, V.I. TANYASHIN, J.R. TATA, NATALIE M. TEICH, R. THOMAS, CONGRESSMAN R. THORNTON, G. THRELFALL, C.F. THURSTON, J. TOOZE, A. VAN KAMMEN, M.C. VAN MONTAGU, J.K. VASS, P. VENETIANER, M.V. VIOLA, L.P. VISENTIN, R. WALLGATE, SIR F. WARNER, I. WATANABE, J.D. WATSON, C. WEINER, D.L. WEISS, EDITH BROWN WEISS, R.A. WEISS, C. WEISSMANN, W.J. WHELAN, R.O. WILLIAMS, W.A. WOLF, E.L. WOLLMAN, SIR G. WOLSTENHOLME, C. WRAY, E.J. YOXEN, S. ZADRAZIL, N.D. ZINDER, SUE DARELL-BROWN, CAROLYN ISON, JOAN MORGAN, NANCY MORRIS, and LINDA READING
- Published
- 1979
- Full Text
- View/download PDF
8. The HL-A System as a Model for Studying the Interaction between Selection, Migration, and Linkage
- Author
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J. Bodmer, W.F. Bodmer, and G. Thomson
- Subjects
Linkage (software) ,Computational biology ,Biology ,Selection (genetic algorithm) - Published
- 1976
- Full Text
- View/download PDF
9. EVOLUTION AND STABILITY OF SPECIES
- Author
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W.F. Bodmer
- Subjects
Genetics ,chemistry.chemical_compound ,Property (philosophy) ,Natural selection ,chemistry ,Reproduction (economics) ,Genotype ,Gene duplication ,Genetic variation ,Mutation (genetic algorithm) ,Biology ,DNA - Abstract
This brief survey of evolution and the nature of species is meant to serve as a background to considering the possible implications of the heterologous combinations that can be synthesized by recombinant DNA techniques. The essence of life is the capacity for self reproduction, which is mediated by the genetic material, DNA (or RNA), and the machinery for its expression and duplication. Without faithful reproduction there can be no biological continuity and so it is an inevitable property of biological systems that genetic changes, or mutations, should be comparatively rare. Mutations do, however, occur and they provide the basic genetic variation which allows evolution to take place. Evolution is progressive genetic change and, as Darwin taught us, has natural selection as its main driving force. Mutation, because it is rare, is not itself a significant force for genetic change. Adaptive evolution thus depends on the differential reproduction and survival of different genotypes leading to increases in frequency of the advantageous at the expense of the less favoured genotypes. Evolution by natural selection may be thought of as Nature's way of counteracting the second law of thermodynamics.
- Published
- 1979
- Full Text
- View/download PDF
10. Nomenclature for factors of the HLA system, 1990
- Author
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J.G. Bodmer, S.G.E. Marsh, E.D. Albert, W.F. Bodmer, B. Dupont, H.A. Erlich, B. Mach, W.R. Mayr, P. Parham, T. Sasazuki, G. M. Th. Schreuder, J.L. Strominger, A. Svejgaard, and P.I. Terasaki
- Subjects
Genetics ,MHC class II ,Immunology ,MHC class I ,biology.protein ,Human leukocyte antigen ,Biology ,Allele ,Nomenclature ,Gene ,Epitope
11. A monoclonal antibody recognizing a human thymus leukemia-like antigen associated with β2-microglobulin
- Author
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W.F. Bodmer and R.W. Knowles
- Subjects
Beta-2 microglobulin ,medicine.drug_class ,Chemistry ,Immunology ,General Medicine ,Monoclonal antibody ,medicine.disease ,Molecular biology ,HUMAN THYMUS ,Leukemia ,Antigen ,Blocking antibody ,medicine ,Immunology and Allergy - Published
- 1982
- Full Text
- View/download PDF
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