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Energy-transport effects can alter the structure that develops as a supernova evolves into a supernova remnant. The Rayleigh–Taylor instability is thought to produce structure at the interface between the stellar ejecta and the circumstellar matter, based on simple models and hydrodynamic simulations. Here we report experimental results from the National Ignition Facility to explore how large energy fluxes, which are present in supernovae, affect this structure. We observed a reduction in Rayleigh–Taylor growth. In analyzing the comparison with supernova SN1993J, a Type II supernova, we found that the energy fluxes produced by heat conduction appear to be larger than the radiative energy fluxes, and large enough to have dramatic consequences. No reported astrophysical simulations have included radiation and heat conduction self-consistently in modeling supernova remnants and these dynamics should be noted in the understanding of young supernova remnants., Radiation and conduction are generally considered as the main energy transport mechanisms for the evolution of early supernova remnants. Here the authors experimentally show the role of electron heat transfer on the growth of Rayleigh–Taylor instability in young supernova remnants.

We discuss changes to a target design that improved the quality and consistency of data obtained through a novel experimental platform that enables the study of hydrodynamic instabilities in a compressible regime. The experiment uses a laser to drive steady, supersonic shockwave over well-characterized initial perturbations. Early experiments were adversely affected by inadequate experimental timescales and, potentially, an unintended secondary shockwave. These issues were addressed by extending the 4x10 13 W/cm 2 laser pulse from 19 ns to 28 ns, and increasing the ablator thickness from 185 µm to 500 µm. We present data demonstrating the performance of the platform.

Double shell targets1 on the National Ignition Facility (NIF) provide for an alternative path to a high yield experiment compared to the single shells. The concept of the design is that through kinetic energy transfer between an outer ablator and inner pusher, conditions needed for robust burn can be achieved with a lower convergence ratio and internal temperature compared to a single shell. Due to the multilayer construction of the target, features that can perturb any of the multiple layers of the capsule and degrade target performance are a concern. Understanding the mechanics of these degradations and ways to prevent them is extremely important for a successful design.

Advances in target fabrication have made double shell capsule implosions a viable platform to study burning fusion plasmas. Central to the double shell capsule is a high-Z (e.g., Au) metal pusher that accesses the volume-burn regime by reducing radiative losses through radiation trapping and compressing a uniform fuel volume at reduced velocities. A double shell implosion relies on a series of energy transfer processes starting from x-ray absorption by the outer shell, followed by transfer of kinetic energy to an inner shell, and finally conversion of kinetic energy to fuel internal energy. We present simulation and experimental results on momentum transfer to different layers in a double shell. We also present the details of the development of the NIF cylindrical hohlraum double shell platform including an imaging shell design with a mid-Z inner shell necessary for imaging the inner shell shape and the trajectory with the current 2DConA platform capability. We examine 1D energy transfer between shell layers using trajectory measurements from a series of surrogate targets; the series builds to a complete double shell layer by layer, isolating the physics of each step of the energy transfer process. The measured energy transfer to the foam cushion and the inner shell suggests that our radiation-hydrodynamics simulations capture most of the relevant collision physics. With a 1 MJ laser drive, the experimental data indicate that 22% ± 3% of the ablator kinetic energy couples into inner shell KE, compared to a 27% ± 2% coupling in our xRAGE simulations. Thus, our xRAGE simulations match experimental energy transfer to ∼5%, without inclusion of higher order 2D and 3D effects.

An experiment meant to investigate the evolution of single mode Kelvin–Helmholtz (KH) instability in the supersonic regime is presented and theoretically analyzed. This experiment is intended to provide a direct measurement of the two-dimensional vortex evolution so that the high-Mach-number effects can be measured. The proposed design takes advantage of the ability of OMEGA-EP to drive experiments for up to 30 ns to produce steady conditions for KH that endure long enough to observe substantial growth. KH growth for the proposed design has been analyzed using two-dimensional numerical simulations. The results were compared to synthetic temporal KH numerical simulations using non-dimensional scaling in the low and high Mach number regime. The comparisons show that the growth in the high Mach number regime is expected to be suppressed by up to a factor of two. The effects of two-dimensional rarefactions from the lateral boundaries of the experimental system were also investigated. It was found that they introduce no major uncertainties or hazards to the experiment. We produced simulated radiographs, which show that the proposed experimental system will enable observation of the KH structures. An experiment of this kind has not yet been performed, and therefore would serve to validate numerical results and analytical models presented here and in the literature.

The origin of the large magnetic fields observed in the interior of the supernova remnant Cassiopeia A is still unclear. Laboratory experiments of laser-produced shocks provide new insights into the mechanisms of magnetic field amplification. X-ray1,2,3 and radio4,5,6 observations of the supernova remnant Cassiopeia A reveal the presence of magnetic fields about 100 times stronger than those in the surrounding interstellar medium. Field coincident with the outer shock probably arises through a nonlinear feedback process involving cosmic rays2,7,8. The origin of the large magnetic field in the interior of the remnant is less clear but it is presumably stretched and amplified by turbulent motions. Turbulence may be generated by hydrodynamic instability at the contact discontinuity between the supernova ejecta and the circumstellar gas9. However, optical observations of Cassiopeia A indicate that the ejecta are interacting with a highly inhomogeneous, dense circumstellar cloud bank formed before the supernova explosion10,11,12. Here we investigate the possibility that turbulent amplification is induced when the outer shock overtakes dense clumps in the ambient medium13,14,15. We report laboratory experiments that indicate the magnetic field is amplified when the shock interacts with a plastic grid. We show that our experimental results can explain the observed synchrotron emission in the interior of the remnant. The experiment also provides a laboratory example of magnetic field amplification by turbulence in plasmas, a physical process thought to occur in many astrophysical phenomena.

We report the measurements of electrostatic field structures associated with an electrostatic shock formed in laser-produced counter-streaming plasmas with proton imaging. The thickness of the electrostatic structure is estimated from proton images with different proton kinetic energies from 4.7 MeV to 10.7 MeV. The width of the transition region is characterized by electron scale length in the laser-produced plasma, suggesting that the field structure is formed due to a collisionless electrostatic shock., Journal of Physics: Conference Series, 688 (1), ISSN:1742-6588, ISSN:1742-6596

The Rayleigh-Taylor (RT) instability is a common occurrence in nature, notably in astrophysical systems like supernovae, where it serves to mix the dense layers of the interior of an exploding star with the low-density stellar wind surrounding it, and in inertial confinement fusion experiments, where it mixes cooler materials with the central hot spot in an imploding capsule and stifles the desired nuclear reactions. In both of these examples, the radiative flux generated by strong shocks in the system may play a role in partially stabilizing RT instabilities. Here, we present experiments performed on the National Ignition Facility, designed to isolate and study the role of radiation and heat conduction from a shock front in the stabilization of hydrodynamic instabilities. By varying the laser power delivered to a shock-tube target with an embedded, unstable interface, the radiative fluxes generated at the shock front could be controlled. We observe decreased RT growth when the shock significantly heats t...

We derive a model describing vorticity deposition on a high-Atwood number interface with a sinusoidal perturbation by an oblique shock propagating from a heavy into a light material. Limiting cases of the model result in vorticity distributions that lead to Richtmyer-Meshkov and Kelvin-Helmholtz instability growth. For certain combinations of perturbation amplitude, wavelength, and tilt of the shock, a regime is found in which discrete, co-aligned, vortices are deposited on the interface. The subsequent interface evolution is described by a discrete vortex model, which is found to agree well with both RAGE simulations and experiments at early times.

Retinoblastoma is a commonly seen and dangerous intraocular malignant tumor in infants. Studies have found that Claudin-1 and MMP-2, whose expressions may be connected, play roles in tissues of retinoblastoma. In this study we analyze and discuss changes of Claudin-1 and MMP-2 expressions, and the correlation between the expressions and retinoblastoma histological differentiation and optic nerve invasion. MaxVisionTM was applied to detect expressions of Claudin-1 and MMP-2 in 45 samples of retinoblastoma and 15 paraffin-embedded samples of normal retina. The correlation between Claudin-1 expression and MMP-2 expression was analyzed based on chi-squared test and Spearman’s correlation test. Positive expressions of Claudin-1 in retinoblastoma were fewer than those in retina; higher positive expressions were found in differentiated tissues than in undifferentiated tissues; while compared to expressions in invasive optic nerves, Claudin-1 expressed more positively in optic nerves without invasion. As for MMP-2, its expressions were higher in retinoblastoma than in normal retina; undifferentiated tissues had higher positive expressions than differentiated tissues, which were not statistically significant; higher positive expressions were detected in invasive optic nerves. Thus, it could be concluded that the correlation between Claudin-1 expression and MMP-2 expression in retinoblastoma was negative. Expressions of Claudin-1 were positively related to histological differentiation and optic nerve invasion of retinoblastoma; while MMp-2 expression had negative correlation with histological differentiation and optic nerve invasion of retinoblastoma. Claudin-1 and MMP-2 played a negative role in the optic nerve invasion and tumor development of retinoblastoma.

We report the first observation, in a supersonic flow, of the evolution of the Kelvin-Helmholtz instability from a single-mode initial condition. To obtain these data, we used a novel experimental system to produce a steady shock wave of unprecedented duration in a laser-driven experiment. The shocked, flowing material creates a shear layer between two plasmas at high energy density. We measured the resulting interface structure using radiography. Hydrodynamic simulations reproduce the large-scale structures very well and the medium-scale structures fairly well, and imply that we observed the expected reduction in growth rate for supersonic shear flow.

We report the first observations of Kelvin-Helmholtz vortices evolving from well-characterized, dual-mode initial conditions in a steady, supersonic flow. The results provide the first measurements of the instability's vortex merger rate and supplement data on the inhibition of the instability's growth rate in a compressible flow. These experimental data were obtained by sustaining a shockwave over a foam-plastic interface with a precision-machined seed perturbation. This technique produced a strong shear layer between two plasmas at high-energy-density conditions. The system was diagnosed using x-ray radiography and was well-reproduced using hydrodynamic simulations. Experimental measurements imply that we observed the anticipated vortex merger rate and growth inhibition for supersonic shear flow.

We present experiments at the Trident laser facility demonstrating the use of x-ray fluorescence (XRF) to simultaneously measure density, ionization state populations, and electron temperature in shocked foams. An imaging x-ray spectrometer obtained spatially resolved measurements of Ti K-α emission. Density profiles were measured from K-α intensity. Ti ionization state distributions and electron temperatures were inferred by fitting K-α spectra to spectra from CRETIN simulations. This work shows that XRF provides a powerful tool to complement other diagnostics to make equation of state measurements of shocked materials containing a suitable tracer element.

This paper discusses the recent research in High-Energy-Density Physics at our Center. Our work in complex hydrodynamics is now focused on mode coupling in the Richtmyer- Meshkov process and on the supersonic Kelvin-Helmholtz instability. These processes are believed to occur in a wide range of astrophysical circumstances. In radiation hydrodynamics, we are studying radiative reverse shocks relevant to cataclysmic variable stars. Our work on magnetized flows seeks to produce magnetized jets and study their interactions. We build the targets for all these experiments, and simulate them using our CRASH code. We also conduct diagnostic research, focused primarily on imaging x-ray spectroscopy and its applications to scattering and fluorescence.

In this work, we present the results of experiments observing the properties of the electron stream generated laterally when a laser irradiates a metal. We find that the directionality of the electrons is dependent upon their energies, with the higher-energy tail of the spectrum (∼1 MeV and higher) being more narrowly focused. This behavior is likely due to the coupling of the electrons to the electric field of the laser. The experiments are performed by using the Titan laser to irradiate a metal wire, creating the electron stream of interest. These electrons propagate to nearby spectator wires of differing metals, causing them to fluoresce at their characteristic K-shell energies. This fluorescence is recorded by a crystal spectrometer. By varying the distances between the wires, we are able to probe the divergence of the electron stream, while by varying the medium through which the electrons propagate (and hence the energy-dependence of electron attenuation), we are able to probe the energy spectrum of the stream.

Experiments at the Trident Laser Facility have successfully demonstrated the use of x-ray fluorescence imaging (XRFI) to diagnose shocked carbonized resorcinol formaldehyde (CRF) foams doped with Ti. One laser beam created a shock wave in the doped foam. A second laser beam produced a flux of vanadium He-α x-rays, which in turn induced Ti K-shell fluorescence within the foam. Spectrally resolved 1D imaging of the x-ray fluorescence provided shock location and compression measurements. Additionally, experiments using a collimator demonstrated that one can probe specific regions within a target. These results show that XRFI is a capable alternative to path-integrated measurements for diagnosing hydrodynamic experiments at high energy density.

Glandular odontogenic cyst (GOC) is an extremely rare lesion occurring in the jawbones. Sialo-odontogenic cyst was first described as a multicystic lesion resembling a botryoid odontogenic cyst (BOC) or a central mucoepidermoid carcinoma by Padayachee in 1987. In 1988, Gardner used the term "glandular odontogenic cyst" and considered it as a histologic variant of BOC. Most authors agreed that GOC was odontogenic because of the concurrent ball-like epithelial structure, ameloblastoma, squamous odontogenic tumor-like proliferation in its wall, or hyaline bodies in the epithelium lining. Recently, immunohistochemical studies of the cytokeratin profiles have also supported this concept. Its aggressive behavior and the recurrent tendency make it important. A new case of GOC in a 59-year-old male presented as a multilocular radiolucency in the anterior region of the mandible, invading the marrow space by epithelial islands is described with other clinicopathologic features and the literature is briefly discussed.

The immunological and biological gonadotropin-releasing hormone (GnRH)-like activities in the acid extract of shrimp hepatopancreas (SHE) were studied. The immunological activity determined by a GnRH radioimmunoassay was 22.3 +/- 2.7 ng per ml of SHE. SHE increased luteinizing hormone (LH) release from rat anterior pituitary glands (APs) in vitro, and its biological activity was 42.9 +/- 28.5 ng per ml. No immunological activity was found in the acid extracts of eye ball, eye stalk, nerve and heart. These results suggest that the shrimp hepatopancreas has both immunological and biological GnRH-like activity.

Immunoreactive (TRH) has been detected in acid and methanol extracts of hepatopancreas, in grass shrimp (black tiger prawn, Penaeus monodon). The evidence provided by the stimulation of thyrotropin (TSH) release from perfused rat anterior pituitary glands in vitro following the application of hepatopancreas extracts (SHE) reflected the presence of TRH-like substance in the shrimp. However, the molecular weight of the TRH-like substance estimated by gel filtration in SHE was greater than that of the synthetic TRH. Furthermore, other differences are also noted, e.g. TRH-like activity in SHE could not be completely neutralized by anti-TRH antiserum nor degraded in normal rat serum.

The production of immunoreactive TSH by hemipituitaries (Hps) to the stimulation of TRH in perifusion with negligible influence of the feedback of secretogogues and hormones was analysed. The stimulations were of long term continuous (3 hrs) and short term (15 min), with the dose levels of 1, 10 and 100 ng per ml of medium (for 3 hrs) or in 2 ml (for 15 min). The largest amount in production and the fastest rate in release of TSH found in present report is at 10 ng level. Only total TSH, in tissue plus in medium, after continuous TRH stimulation were dose-related, but not in release alone. We present herein an analysis of pituitary TSH production, in a perifusion system under steady TRH stimulation. This arrangement is believed to be a condition simulating hypothyroidism in pituitary level and suitable for study of the functions of the pituitary with hyperactivated thyrotrophs.