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2. A concise access to 3-substituted 2-pyrones.

Author

Frébault F, Oliveira MT, Wöstefeld E, and Maulide N

Subjects
Catalysis, Cross-Linking Reagents chemistry, Molecular Structure, Pyrones chemistry, Stereoisomerism, Pyrones chemical synthesis
Abstract

The development of a modular synthesis of 3-substituted-2-pyrones is described. The attainment of this strategy hinges on a new electrophilic pyrone derivative which can be readily prepared on a multigram scale and which performs very competently in metal-catalyzed cross-coupling reactions with a variety of nucleophiles.

Published
2010
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