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The study was carried out in the department of forensic medicine at Government College and hospital, Nagpur over a period of one and half year on 200 dead bodies of victims of road traffic fatalities brought to mortuary for medico-legal post mortem examination. The aim of study was correlation between injury severity score (ISS) and survival time of victim of road traffic accidental deaths. The ISS was calculated from abbreviated injury scale (AIS). The cases were divided into four groups based on their ISS, where the group with less serious injuries (ISS<25) was considered survivable The second group (ISS 25-49) was considered as severe, third group (ISS 49-74) was critical and four group (ISS 75) was fatal . Survival time was more in victims of road traffic accidents who had injury severity score (ISS) less than 25. On the contrary to this, victims who had ISS more than 25 (25-74), survival time was low. Victims who had ISS 75 died on spot or within 1 hours of fatal road traffic accidents. The ISS score is negatively correlated with the survival time with pearson's correlation coefficient r=-.0.419 which is highly significant (p<0.0001). [ABSTRACT FROM AUTHOR]