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The possibility of extending the patterns characteristic of the information process to the educational process is substantiated in this paper. The features of the manifestation of information security properties in the context of educational activities related to the training of specialists in the field of information security are considered. The disadvantages of evaluating this property by quantitative methods are analyzed. It substantiates the possibility of assessing the security of educational activity by qualitative methods. Classification grounds for systematization of security characteristics are determined. The structure of the characteristics of the security of educational activities for the training of specialists in the field of information security is given. Methodological provisions for the implementation of the synthesis procedure of this structure are formulated. Variants of characteristic tables and an example of a decision table for assessing the values of the security characteristics of educational activities in terms of a linguistic scale are given. The results obtained will allow us to assess the feasibility of carrying out measures practically to ensure the information security of educational activities. The developed method can be considered as a methodological support for solving the practical problem of assessing the security of educational activities.

Phytochemical investigation of the whole plants of Lycopodiella cernua resulted in the isolation and identification of three new compounds (1–3), namely lycocernuaside E (1), lycernuic ketone F (2)...

Phytochemical investigations of Blumea balsamifera branches and leaves led to the isolation of ten secondary metabolites, including three new compounds, namely, balsamiferine K (1) and balsamiferosides A (2) and B (3). Structural elucidation was confirmed by detailed analysis of the 1D and 2D NMR spectra as well as HR-ESI-QTOF mass spectra. Among the isolated compounds, blumeaene J (4) exhibited moderate cytotoxicity against LNCaP (IC50 = 44.53 ± 4.95 μM) and SK-Mel2 (IC50 = 46.49 ± 3.84 μM) cell lines and weak effects on HepG2 (IC50 = 61.54 ± 2.98 μM), KB (IC50 = 65.40 ± 4.97 μM), and MCF-7 (IC50 = 70.06 ± 5.65 μM) cell lines, whereas (―)-angelicoidenol 2-O-β- d -glucopyranoside (6) revealed weak activity on all five tested cancer cell lines, with IC50 values ranging from 61.60 ± 5.64–98.73 ± 2.24 μM.

Endophytic microbia are known as natural sources for producing valuable enzymes. In this study, four endophytic fungi were isolated from roots of local Catharanthus roseus (L.) G. Don var. roseus (purple flower) and C. roseus var. ocellatus (red stamens white flower) widely grown in Nha Trang. They were identified as Fusarium solani RN1, Chaetomium funicola RN3, Penicillium rugulosum RN4 and Chaetomium homopilatum WN1 based on morphologies colonies and spores. The activity analysis of their extracellular enzymes indicted all isolated endophytic fungi are able to produce protease, cellulose, xylanase as well as amylase. This is the first report on the endophytic fungi inhabited in C. roseus plant growing in the coastal regions of Vietnam, which could provide an attractive source for bioactive enzyme exploitation.

Using combined chromatographic separation techniques, three new triterpenoids named lycomclavatols A-C (

Phytochemical investigation of the whole plants of

In Vietnam, many studies exist on HIV and the lives of the people living with HIV, however, they often concentrate on the way of virus is transmitted and its prevention. Some research has focused on the ostracism and discrimination from their families or the community who play roles in caring and following the treatment of them.By interviewing nearly thirty women living with HIV in Ho Chi Minh City and applying the symbolic interactionism and the labelling theories, our thesis considers questions and discovers that most of the women who are infected by their husbands/ partners have had enormous shock after being diagnosed as HIV positive.After psychological shock, these following objects of study analyse their health, occupation, the change in life paradigm , the social stigmatisms and their self-stigma. Therefor, to continue living, they have to re-build new relationships or behaviours both on an individual and on communal scale.; Au Vietnam, il existe de nombreuses études portant sur le VIH en général et le vécu des personnes atteintes, mais ces travaux se concentrent souvent sur les voies de transmission et les mesures de prévention à mettre en place. Certaines recherches, cependant, se sont focalisées sur l’ostracisme et la discrimination dont sont victimes, de la part de leur famille ou de la société, ces personnes, et le rôle que joue l’entourage dans la prise en charge de ces malades, notamment pour leur traitement.En interrogeant près d’une trentaine de femmes vivant avec le VIH à Hô Chi Minh-Ville, et en appliquant les théories de l’interactionnisme symbolique et de l’étiquetage, notre thèse réexamine ce questionnement et montre que la plupart d’entre elles avaient été infectées par leur mari et avaient subi un énorme choc en apprenant leur séropositivité.À la suite de ce traumatisme, la santé, l’emploi et les modes de sociabilité ont changé, les attitudes de stigmatisation – auto-infligée ou provenant de l’environnement – faisant l’objet d’une analyse approfondie. Dès lors, pour continuer à exister, il a fallu réinventer de nouveaux types de relations ou de comportements tant au niveau individuel que sur un plan communautaire. .

Grey mangrove (Avicennia marina) is a traditional medicine used for the treatment of various diseases, including rheumatism and ulcers; however, the compounds responsible for its curative effects remain largely unknown. Triterpenoids are a diverse group of plant-specialized metabolites derived from a common precursor, 2,3-oxidosqualene. Triterpenoids are potentially responsible for the beneficial effects of A. marina; however, the chemical profiles of triterpenoids in A. marina and their biosynthetic genes have not been identified. Cytochrome P450 monooxygenases (P450s) have key roles in the structural diversification of plant triterpenoids by catalyzing site-specific oxidation of triterpene scaffolds. Recent studies have revealed that the CYP716 family represents the most common clade of P450s involved in triterpenoid biosynthesis. In this study, we performed triterpenoid profiling and RNA sequencing of A. marina leaves. Mining of CYP716 family genes and enzymatic activity assays of encoded proteins revealed that CYP716A259 catalyzed oxidation at the C-28 position of the pentacyclic triterpene skeletons of β-amyrin, α-amyrin, and lupeol to produce oleanolic acid, ursolic acid, and betulinic acid, respectively. The other functionally defined P450, CYP716C53, catalyzed the C-2α hydroxylation of oleanolic acid and ursolic acid to produce maslinic acid and corosolic acid, respectively. The possible involvement of CYP716A259 and CYP716C53 in the biosynthesis of these health-benefiting compounds in A. marina leaves, and the possible contribution of the resulting compounds to the reported bioactivities of A. marina leaf extract, are discussed.

Five new compounds, named ancistronaphtosides A and B (1 and 2), anciscochine (3), anciscochine 6-O-β-d-glucopyranoside (4), and 4'-methoxy-5-epi-ancistecrorine A1 (5), together with tortoside A (6) and 4-hydroxy-2-methoxyphenyl-6-O-syringoyl-β-d-glucopyranoside (7) were isolated from the methanolic extract of Ancistrocladus cochinchinensis. Their chemical structures were established using HR-ESI-MS, NMR spectroscopic, and chiroptical methods. Compound 5 significantly exhibited anti-proliferation against HL-60, LU-1, and SK-MEL-2 cells with IC50 values of 5.0±1.2, 6.5±1.6, and 6.8±2.0μg/mL, respectively.

Using various chromatographic methods, one new lanostane triterpene, 3 α-hydroxylanosta-8,24 E-dien-26-oic acid (1), one new lignan, matairesinol 4'- O-β-D-glucopyranoside (2) along with five known compounds, ecdysone (3), 20-hydroxyecdysone (4), 20-hydroxyecdysone 2,3-monoacetonide (5), turkesterone (6), and polypodine B (7) were isolated from the leaves of Vitex trifolia L. Their structures were elucidated by 1D-, 2D-NMR spectroscopic analysis, HR-ESI-MS, CD, and by comparing with the NMR data reported in the literature.

Using various chromatography methods, a saponin, ginsenoside Rg1 (1), and three phenolic glycosides, tortoside A (2), phlorizin (3), and 4-hydroxy-2-methoxyphenyl-6-O-syringyl-b-D-glucopyranoside (4) were isolated from the water-soluble fraction of Ancistrocladus cochinchinensis. Their structures were elucidated by 1D- and 2D-NMR spectroscopic analyses and comparison with those reported in the literature. Compound 1 was reported from A. cochinchinensis for the first time.

This work was done as a part of our ongoing projects to catalog the chemical constituents and biological activities of the Morinda species growing in Vietnam. Phytochemical investigations of the methanol extract of Morinda umbellata aerial parts resulted in the isolation of two new 11-noriridoids, umbellatolides A (1) and B (2). Their structures were elucidated by NMR (1H NMR, 13C NMR, HSQC, HMBC, 1H–1H COSY, and NOESY) and FTICRMS data. This is the first report of 11-noriridoids from M. umbellata. The cytotoxic activity and protective effect on oxidative stress injury stimulated by H2O2 in murine hepatocyte of 1 and 2 were also evaluated.

Six secondary metabolites, including two novel iridoids, longifolides A (1) and B (2), were isolated by various chromatographic methods from a methanol extract of branches and leaves of Morinda longifolia Craib. The structures of the compounds were determined on the basis of NMR spectroscopic (1H and 13C NMR, HSQC, HMBC, 1H-1H COSY, NOESY) and FTICR-MS data, as well as by comparison of them with literature values.