16 results on '"Vrdelja, M."'
Search Results
2. P25-05: Media representation of Glyphosate in Slovenian Printed Media over 10 year period
- Author
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Kolar, U., primary and Vrdelja, M., additional
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- 2023
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3. Defining the scope of the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet): a bottom-up and One Health approach
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Mader, R., Demay, C., Jouvin-Marche, E., Ploy, M. -C., Barraud, O., Bernard, S., Lacotte, Y., Pulcini, C., Weinbach, J., Berling, C., Bouqueau, M., Hlava, A., Habl, C., Kernstock, E., Strauss, R., Muchl, R., Buhmann, V., Versporten, A., Ingenbleek, A., Vandael, E., Haelterman, G., De Raedt, L., Hunjak, B., Raickovic, B., Mackova, B., Niklova, E., Zemlickova, H., Hrivnakova, L., Jindrak, V., Kristensen, B., Lyndrup, M., Skovgaard, S., Wolf Sonksen, U., Aasmae, B., Ruut, J., Linnik, L., Sadikova, O., Martin, P., Zanuzdana, A., Kizilkaya-Guneser, G., Oezcelik, N., Eckmanns, T., Lambrou, A., Kontopidou, F., Papadaki, M., Tsana, M., Maroulis, N., Vatopoulos, A., Papadogiannakis, E., Kontarini, M., Gikas, A., Magkanaraki, A., Cozza, A., Martinelli, D., Fortunato, F., Prato, R., Marella, A. M., Pantosti, A., Prestinaci, F., Busani, L., Pezzoti, P., Creti, R., Martoccia, R. M., Brusaferro, S., Vilde, A., Jakovela, A., Langusa, E., Grudule, L., Grinsteine, M., Dumpis, U., Dambrauskiene, A., Vitkauskiene, A., Tirvaite, D., Cemnalianskis, L., Kazenaite, E., Lozoraitiene, I., Adomaitiene, R., Ambrazaitiene, R., Kiveryte, S., Maciulaityte, A., Kuklyte, J., Petrene, J., Valinteliene, R., Kanapeckiene, V., Razmiene, A., Kairiene, B., Aleksiene, G., Valinciute, G., Petraitis, R., Elsemulder, A., Nakched, A., Claessen, J., Gui, L., Kort, M. D., Peran, R., Van Leeuwen, A., Smeets, E., Mennen, M., Spruijt, P., Westerhof, R., Skulberg, A., Bakka, E. Ro., Miard, K., Henricsen, S. Ho., Pellerud, A., Kallberg, C., Ardal, C., Eriksen, H. -M., Kranstad, K., Molvik, M., Kacelnik, O., Sollund, P., Samuelsen, R., Bakke, T., Urdahl, A. M., Norstrom, M., Olczak-Pienkowska, A., Skoczynska, A., Zabicka, D., Bysiek, J., Rekawek, J., Lebre, A., Falcao, E., Scripcaru, G., Neves, I., Gomes, S., Pereira, N., Malutan, A. M., Iuhas, C., Szakacs, L., Kissiedou-Bob, M., Ciortea, R., Grilc, E., Klavs, I., Turk, K., Subelj, M., Vrdelja, M., Serdt, M., Jemec, N., Glavan, U., Simonovic, Z., Tamayo, A. N., Lopez Navas, A., Munoz Madero, C., Alonso Lebrero, J. L., Alonso Irujo, L., Santacreu Garcia, M., Crespo Robledo, P., Oliva, G., Massanes, M., Oliver Palomo, A., Garcia Pineda, A., Ferragut, E., Rojo, E., Castano, E., Perianez, L., Torres Cantero, A. M., Jimenez Guillen, C., Hukelova, H., Alcaraz, M., Carlos, M. A., Lopez Acuna, M. D. P., Gil Setas, A., Ibarrola Segura, A., Ezpeleta, C., Gahigiro Merino, C., Portillo Bordonabe, M. E., Fragoso, M., Beristain Rementeria, X., Penalva, G., Cisneros, J. M., Estevez, M., Monteau, S., Del Rio, L., Gonzalez De Suso, M. J., Gallego Berciano, P., Aranguren Oyarzabal, A., Alioto, D., Izquierdo Palomares, J. M., Calvo Alcantara, M. J., Gonzalez Perez, R., Havarria, T., Hulth, A., Carlin, K., Edman, L., Grape, M., Aspevall, O., Haggar, A., Lindal, E., Burgos, A., Ottoson, J., Ostman, M., Egervarn, M., Nordenfelt, A., Bengtsson, B., Soderman, I., Bjers, A., Jonsson, J. -I., Starborg, M., Laine, M., Fagerstedt, P., Metcalfe, A., Soder, J., Lytsy, B., Madec, J. Y., Collineau, L., Berger-Carbonne, A., Colomb-Cotinat, M., Bourely, C., Amat, J. -P., Broens, E. M., Callens, B., Crespo-Robledo, P., Damborg, P., Filippitzi, M. -E., Fitzgerald, W., Gronthal, T., Haenni, M., Heuvelink, A., Van Hout, J., Kaspar, H., Pedersen, K., Pokludova, L., Dal Pozzo, F., Slowey, R., Zafeiridis, C., Madec, J. -Y., and Departments of Faculty of Veterinary Medicine
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Microbiology (medical) ,Veterinary medicine ,Staphylococcus pseudintermedius ,040301 veterinary sciences ,Swine ,Drug Resistance ,413 Veterinary science ,0403 veterinary science ,Animals ,Anti-Bacterial Agents ,Bacteria ,Cats ,Cattle ,Chickens ,Dogs ,Drug Resistance, Bacterial ,Female ,One Health ,03 medical and health sciences ,Antibiotic resistance ,Antimicrobial stewardship ,Medicine ,Pharmacology (medical) ,2. Zero hunger ,Streptococcus uberis ,Pharmacology ,0303 health sciences ,biology ,030306 microbiology ,business.industry ,Bacterial ,04 agricultural and veterinary sciences ,biology.organism_classification ,Antimicrobial ,Food safety ,3. Good health ,Infectious Diseases ,business ,Streptococcus dysgalactiae - Abstract
BackgroundBuilding the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet) was proposed to strengthen the European One Health antimicrobial resistance (AMR) surveillance approach.ObjectivesThe objectives were to (i) define the combinations of animal species, production types, age categories, bacterial species, specimens and antimicrobials to be monitored in EARS-Vet and to (ii) determine antimicrobial test panels able to cover most combinations.MethodsThe EARS-Vet scope was defined by consensus between 26 European experts. Decisions were guided by a survey of the combinations that are relevant and feasible to monitor in diseased animals in 13 European countries (bottom-up approach). Experts also considered the One Health approach and the need for EARS-Vet to complement existing European AMR monitoring systems coordinated by the European Centre for Disease Prevention and Control (ECDC) and the European Food Safety Authority (EFSA).ResultsEARS-Vet would monitor AMR in six animal species (cattle, swine, chicken (broiler and laying hen), turkey, cat and dog), for 11 bacterial species (Escherichia coli, Klebsiella pneumoniae, Mannheimia haemolytica, Pasteurella multocida, Actinobacillus pleuropneumoniae, Staphylococcus aureus, Staphylococcus pseudintermedius, Staphylococcus hyicus, Streptococcus uberis, Streptococcus dysgalactiae and Streptococcus suis). Relevant antimicrobials for their treatment were selected (e.g. tetracyclines) and complemented with antimicrobials of more specific public health interest (e.g. carbapenems). Three test panels of antimicrobials were proposed covering most EARS-Vet combinations of relevance for veterinary antimicrobial stewardship.ConclusionsWith this scope, EARS-Vet would enable to better address animal health in the strategy to mitigate AMR and better understand the multi-sectoral AMR epidemiology in Europe.
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- 2022
4. Digital health literacy in general populations – An international comparison
- Author
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Van Den Broucke, S, primary, Levin-Zamir, D, additional, Schaeffer, D, additional, Pettersen, K, additional, Guttersrud, Ø, additional, Finbråten, H, additional, Telo de Arriaga, M, additional, Vrdelja, M, additional, Link, T, additional, and Pelikan, J, additional
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- 2020
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5. Exploring the Inherent Heterogeneity of Vaccine Hesitancy: A Study of a Childhood-Vaccine-Hesitant Population.
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Lamot M, Kirbiš A, and Vrdelja M
- Abstract
Vaccine hesitancy and its determinants have been previously widely researched. Vaccine hesitancy has been defined as a continuum of attitudes, ranging from accepting vaccines with doubts to rejecting them. The present study aims to explore the heterogeneity of a childhood-vaccine-hesitant group by using a person-oriented approach-latent profile analysis. A non-representative cross-sectional sample of vaccine-hesitant Slovenians (N = 421, M
age = 35.21, 82.9% women) was used to identify differences based on their reliance on personal research ("self" researching instead of relying on science), overconfidence in knowledge, endorsement of conspiracy theories, complementary and alternative medicine, and trust in the healthcare system. The analysis revealed three profiles of vaccine-hesitant individuals. The most hesitant profile-vaccine rejecting-expressed the greatest reliance on personal research, expressed the highest endorsement of conspiracy theories and complementary and alternative medicine, showed moderate overconfidence in their knowledge, and expressed the highest levels of distrust in the healthcare system. We further found differences in sociodemographic structure and that the identified profiles differed in their attitudes regarding MMR, HPV, and Seasonal Influenza vaccinations. The present study demonstrates the heterogeneity of the vaccine-hesitant community and offers insights into some of the traits, which are crucial for designing pro-vaccine campaigns.- Published
- 2024
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6. Is Trust in Information Sources Associated with Drug Use? A Population-Based Study.
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Gabrovec B, Crnkovič N, Vrdelja M, Cesar K, and Selak Š
- Abstract
Aim: Communication and information sources can play an important role when addressing drug use. The aim of this study is to assess the association of different levels of trust in information sources regarding drug use within different population groups., Methods: Data was gathered using a mixed methods approach, with an online survey and interviews. A structured questionnaire was designed for data collection using the methodology of the European Monitoring Centre for Drugs and Drug Addiction, with additional items measuring trust in the information sources., Results: In total 9,161 inhabitants of Slovenia aged 15-64 years and living in the private households completed the survey as part of this non-experimental quantitative study (response rate: 57%). A total of 20.7% of the participants reported having used cannabis or hashish at least once in their lives, 2.5% cocaine/crack cocaine and 0.4% heroin. Mean age of the first cannabis/hashish use was 19.59 years, cocaine/crack cocaine 22.73 years and heroin 20.63 years. The participants most value and trust the information sources regarding tobacco, alcohol and illicit drugs if it comes from healthcare workers or immediate family and other relatives, and put the least trust in the internet and television., Conclusions: The data show that drug users have less trust in the given information sources compared to the whole sample. The present research serves as evidence for development and implementation of targeted interventions, including communication activities and tools., Competing Interests: CONFLICTS OF INTEREST The authors report there are no competing interests or conflicts of interest to declare., (© 2023 Branko Gabrovec et al., published by Sciendo.)
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- 2023
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7. Psychological Well-Being and Resilience of Slovenian Students During the COVID-19 Pandemic.
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Ropret N, Košir U, Roškar S, Klopčič V, and Vrdelja M
- Abstract
Introduction: Students' mental health is recognised as an important public health issue, and the strict measures and many changes resulting from the COVID-19 pandemic may have exacerbated this. The aims of the study were thus to explore psychological well-being among university students in Slovenia during the beginning of the second lockdown, and to assess associations among their psychological well-being, demographic characteristics, presence of a chronic health condition, and resilience., Methods: The Slovenian online cross-sectional survey was performed as part of a large-scale international survey led by the COVID-HL Consortium, between the 2nd and 23rd November 2020. The study was carried out on a sample of 3,468 university students (70% female) in Slovenia, aged between 18 to 40 (M=22/SD=3). In addition to sociodemographic data and that on the presence of a chronic health condition, data on subjective social status (SSS), psychological well-being (WHO-5) and resilience (CD-RISC 10) was also gathered., Results: In our study 52% of university students reported good psychological well-being. Hierarchical binary logistic regression revealed that male, older students, those with higher perceived subjective social status, students without a chronic health condition, and those with higher score on resilience were more likely to have good psychological well-being. Resilience was the strongest predictor of psychological well-being in our study., Conclusions: Systematic preventive approaches/interventions in the field of mental health should be implemented among students in Slovenia. In this context it is important to develop and deliver programmes for enhancing resilience, which is an important protective factor in times of mental distress., (© 2023 Nina ROPRET et al., published by Sciendo.)
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- 2023
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8. Author Correction: The influence of anxiety and fear of COVID-19 on vaccination hesitancy among postsecondary students.
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Šorgo A, Crnkovič N, Cesar K, Selak Š, Vrdelja M, and Gabrovec B
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- 2023
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9. The influence of anxiety and fear of COVID-19 on vaccination hesitancy among postsecondary students.
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Šorgo A, Crnkovič N, Cesar K, Selak Š, Vrdelja M, and Gabrovec B
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- Humans, Cross-Sectional Studies, Prospective Studies, Vaccination Hesitancy, Anxiety epidemiology, Fear, Students, COVID-19 epidemiology, COVID-19 prevention & control
- Abstract
The aim of the present study was to explore the influence of anxiety and fear of COVID-19 on vaccination hesitancy among Slovenian postsecondary students. A cross-sectional study using a set of previously tested instruments and ad hoc questions created by the authors was chosen as the method to gain insight into various health and sociodemographic aspects of Slovenian postsecondary students affected by the COVID-19-induced closures and suspensions of educational activities at tertiary educational institutions (N = 5999). Overall, 39.7% of participating students expressed an intention to get vaccinated at the first possible opportunity, whereas 29.2% expressed no intent to do so. The highest vaccine hesitancy was observed among prospective teachers (50.3%) and the lowest among prospective physicians (5,7%). When examining the role of anxiety and fear of COVID-19 on the Slovenian postsecondary students' intentions to get vaccinated the results of logistic regression showed that only fear of COVID-19 played a mild and significant role., (© 2022. The Author(s).)
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- 2022
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10. Measuring Comprehensive, General Health Literacy in the General Adult Population: The Development and Validation of the HLS 19 -Q12 Instrument in Seventeen Countries.
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Pelikan JM, Link T, Straßmayr C, Waldherr K, Alfers T, Bøggild H, Griebler R, Lopatina M, Mikšová D, Nielsen MG, Peer S, and Vrdelja M
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- Surveys and Questionnaires, Psychometrics, Factor Analysis, Statistical, Language, Reproducibility of Results, Health Literacy
- Abstract
Background: For improving health literacy (HL) by national and international public health policy, measuring population HL by a comprehensive instrument is needed. A short instrument, the HLS
19 -Q12 based on the HLS-EU-Q47, was developed, translated, applied, and validated in 17 countries in the WHO European Region., Methods: For factorial validity/dimensionality, Cronbach alphas, confirmatory factor analysis (CFA), Rasch model (RM), and Partial Credit Model (PCM) were used. For discriminant validity, correlation analysis, and for concurrent predictive validity, linear regression analysis were carried out., Results: The Cronbach alpha coefficients are above 0.7. The fit indices for the single-factor CFAs indicate a good model fit. Some items show differential item functioning in certain country data sets. The regression analyses demonstrate an association of the HLS19 -Q12 score with social determinants and selected consequences of HL. The HLS19 -Q12 score correlates sufficiently highly (r ≥ 0.897) with the equivalent score for the HLS19 -Q47 long form., Conclusions: The HLS19 -Q12, based on a comprehensive understanding of HL, shows acceptable psychometric and validity characteristics for different languages, country contexts, and methods of data collection, and is suitable for measuring HL in general, national, adult populations. There are also indications for further improvement of the instrument.- Published
- 2022
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11. HLS 19 -NAV-Validation of a New Instrument Measuring Navigational Health Literacy in Eight European Countries.
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Griese L, Finbråten HS, Francisco R, De Gani SM, Griebler R, Guttersrud Ø, Jaks R, Le C, Link T, Silva da Costa A, Telo de Arriaga M, Touzani R, Vrdelja M, Pelikan JM, and Schaeffer D
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- Humans, Reproducibility of Results, Psychometrics, Factor Analysis, Statistical, Surveys and Questionnaires, Health Literacy
- Abstract
To manoeuvre a complex and fragmented health care system, people need sufficient navigational health literacy (NAV-HL). The objective of this study was to validate the HLS
19 -NAV measurement scale applied in the European Health Literacy Population Survey 2019-2021 (HLS19 ). From December 2019 to January 2021, data on NAV-HL was collected in eight European countries. The HLS19 -NAV was translated into seven languages and successfully applied in and validated for eight countries, where language and survey method differed. The psychometric properties of the scale were assessed using confirmatory factor analysis (CFA) and Rasch modelling. The tested CFA models sufficiently well described the observed correlation structures. In most countries, the NAV-HL data displayed acceptable fit to the unidimensional Rasch partial credit model (PCM). For some countries, some items showed poor data-model fit when tested against the PCM, and some items displayed differential item functioning for selected person factors. The HLS19 -NAV demonstrated high internal consistency. To ensure content validity, the HLS19 -NAV was developed based on a conceptual framework. As an estimate of discriminant validity, the Pearson correlations between the NAV-HL and general health literacy (GEN-HL) scales were computed. Concurrent predictive validity was estimated by testing whether the HLS19 -NAV, like general HL measures, follows a social gradient and whether it forms a predictor of general health status as a health-related outcome of general HL. In some countries, adjustments at the item level may be beneficial.- Published
- 2022
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12. Compliance with Preventive Measures and COVID-19 Vaccination Intention among Medical and Other Healthcare Students.
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Gabrovec B, Selak Š, Crnkovič N, Šorgo A, Cesar K, Fafangel M, Vrdelja M, and Trop Skaza A
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- COVID-19 Vaccines therapeutic use, Cross-Sectional Studies, Female, Humans, Intention, Male, Patient Acceptance of Health Care, Vaccination, COVID-19 epidemiology, COVID-19 prevention & control, Influenza Vaccines, Influenza, Human prevention & control, Students, Medical
- Abstract
Introduction: The purpose of this study is to evaluate compliance with preventive measures and COVID-19 vaccination acceptance among Slovenian students of healthcare and medicine, identify the predictive socio-demographic factors, establish the possible causes, and propose vaccination strategies and programs in response to the findings., Methods: Data were collected using an online survey as part of a large cross-sectional study of full-time students engaged in higher-level study. The survey took place between 9 February and 8 March 2021., Results: A total of 56.3% of medical and other healthcare students surveyed expressed their intention to receive the vaccine at the earliest opportunity, 22.4% said that they would do so at a later date and 21.3% said that they did not intend to get vaccinated. The medical students surveyed showed a greater readiness to get vaccinated at the earliest opportunity than those studying other healthcare disciplines, men more than women, and single persons more than those in a relationship. Students attending a vocational college, professional higher education or university study program (Bologna first cycle) showed less readiness than other students to get vaccinated as soon as they were able., Conclusion: Our research found that 56.3% of those studying health-related subjects intended to get vaccinated at the earliest opportunity. There were significant differences between medical and other healthcare students, as well as differences resulting from the level of higher education study being undertaken. In addition, the conclusions show that there needs to be a strengthening of communication with students regarding COVID-19 and the importance of vaccination. Lessons that we learned in this pandemic should prepare us for the future. Clearer and more effective communication and education in the future regarding the importance of vaccination is the most effective way of preventing communicable diseases.
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- 2022
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13. The HLS 19 -COM-P, a New Instrument for Measuring Communicative Health Literacy in Interaction with Physicians: Development and Validation in Nine European Countries.
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Finbråten HS, Nowak P, Griebler R, Bíró É, Vrdelja M, Charafeddine R, Griese L, Bøggild H, Schaeffer D, Link T, Kucera Z, Mancini J, and Pelikan JM
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- Communication, Humans, Psychometrics, Reproducibility of Results, Surveys and Questionnaires, Health Literacy, Physicians
- Abstract
Background: Sufficient communicative health literacy (COM-HL) is important for patients actively participating in dialogue with physicians, expressing their needs and desires for treatment, and asking clarifying questions. There is a lack of instruments combining communication and HL proficiency. Hence, the aim was to establish an instrument with sufficient psychometric properties for measuring COM-HL., Methods: The HLS
19 -COM-P instrument was developed based on a conceptual framework integrating HL with central communicative tasks. Data were collected using different data collection modes in nine countries from December 2019 to January 2021 ( n = 18,674). Psychometric properties were assessed using Rasch analysis and confirmatory factor analysis. Cronbach's alpha and Person separation index were considered for reliability., Results: The 11-item version (HLS19 -COM-P-Q11) and its short version of six items (HLS19 -COM-P-Q6) fit sufficiently the unidimensional partial credit Rasch model, obtained acceptable goodness-of-fit indices and high reliability. Two items tend to under-discriminate. Few items displayed differential item functioning (DIF) across person factors, and there was no consistent pattern in DIF across countries. All items had ordered response categories., Conclusions: The HLS19 -COM-P instrument was well accepted in nine countries, in different data collection modes, and could be used to measure COM-HL., Competing Interests: The authors declare no conflict of interest.- Published
- 2022
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14. Facing the Growing COVID-19 Infodemic: Digital Health Literacy and Information-Seeking Behaviour of University Students in Slovenia.
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Vrdelja M, Vrbovšek S, Klopčič V, Dadaczynski K, and Okan O
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- Adult, Cross-Sectional Studies, Female, Humans, Information Seeking Behavior, Internet, Pandemics, Reproducibility of Results, SARS-CoV-2, Slovenia epidemiology, Students, Surveys and Questionnaires, Universities, Young Adult, COVID-19, Health Literacy
- Abstract
The entire world is faced with the COVID-19 pandemic, which is also accompanied by an infodemic. This refers to the rapid spread of (accurate and false) information, mainly through internet usage increasing. Digital health literacy (DHL) is therefore important for addressing challenges related to online health information and services, as well as for navigation through the complex information landscape with huge amounts of different (and conflicting) information about COVID-19. The aim of this study is to examine the level of DHL in relation to COVID-19 in Slovenian university students and to determine online information-seeking behaviour in order to plan and prepare effective communication interventions for this sub-population. A cross-sectional survey, administered by an online questionnaire, was conducted to collect data on DHL. A total of 3621 students participated, of whom 70% were female and the average age was 22.65 years (SD = 4.65). Bivariate analyses were performed to assess the association of key characteristics with DHL. Overall, the results show that the level of DHL among students is sufficient. Most difficulties were reported in assessing the reliability of information ( n = 1484, 49.3%). Approximately one third of the students ( n = 847, 27.9%) reported having problems in finding information of their interest, and somewhat more ( n = 900, 29.6%) reported difficulties in making a selection among all the information found. Students with a sufficient level of DHL are more likely to seek information through search engines and websites of official institutions, while students with a limited level of DHL more frequently reported using social media for health information searches. It is necessary to establish interventions for a systematic lift of the DHL and health literacy (HL) of all population groups.
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- 2021
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15. The growing vaccine hesitancy: exploring the influence of the internet.
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Vrdelja M, Kraigher A, Vercic D, and Kropivnik S
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- Adult, Communicable Disease Control, Decision Making, Female, Health Knowledge, Attitudes, Practice, Humans, Male, Middle Aged, Patient Acceptance of Health Care statistics & numerical data, Slovenia, Surveys and Questionnaires, Vaccination statistics & numerical data, Communicable Diseases drug therapy, Internet, Parents psychology, Patient Acceptance of Health Care psychology, Social Media, Vaccination psychology, Vaccines therapeutic use
- Abstract
Background: Vaccination coverage is dropping in several countries, including Slovenia. More and more people hesitate or even reject vaccinations. As the influence of the internet grows, the question becomes how to communicate about vaccination to parents in order to prevent this drop in vaccination coverage among children., Methods: For the first time in Europe, the Situational Theory of Publics (STOP) has been used in the field of vaccination to segment mothers to subpublics, and to prescribe a clearly defined form of communication for each of the segmented groups. In the survey, 1704 mothers participated who gave birth in 2014 and 2015 in Slovenia., Results: The study showed that mothers react passively to information on vaccination no matter whether they come across it coincidentally or intentionally. Most often, they seek information about vaccination from friends or online. The more concerned they are about the safety of vaccines, the more they search for information about vaccination, and their communication is consequently more active. The mothers that problematize the safety of vaccines more, and are afraid of their adverse events tend to be in favour of alternative options., Conclusions: Our research demonstrated that the STOP can be applied to the field of vaccination. There is a huge need for intensive professional communication about vaccination on the internet and social media. The improvement of the communicational competences of doctors and healthcare workers is essential to achieve better communication with parents and the media, and needs to be focused on mothers and pregnant women.
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- 2018
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16. European Antibiotic Awareness Day (EAAD): any impact on antibiotic consumption and public awareness in Slovenia?
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Cizman M, Plankar Srovin T, Beovic B, Vrdelja M, Bajec T, and Blagus R
- Subjects
- Attitude of Health Personnel, Drug Utilization statistics & numerical data, Humans, Inpatients, Interrupted Time Series Analysis, Outpatients, Slovenia, Anti-Bacterial Agents therapeutic use, Awareness, Bacteria drug effects, Bacterial Infections drug therapy, Drug Resistance, Bacterial, Drug Utilization trends
- Abstract
Objectives: To evaluate the impact of European Antibiotic Awareness Day (EAAD) on antibiotic consumption, improvements in general public awareness and antibiotic resistance in Slovenia., Methods: Outpatient data for the period from 2002 to 2016 and hospital antibiotic consumption data for 2004-16 were collected using the Anatomical Therapeutic Chemical (ATC) classification/DDDs. Outpatient antibiotic consumption data were expressed in DDDs/1000 inhabitants/day (DIDs), number of packages/1000 inhabitant-days and number of prescriptions/1000 inhabitants/year. Hospital consumption data were expressed in DIDs, number of DDDs/100 bed-days and number of DDDs/100 admissions. Segmented regression analysis of interrupted time series was used to estimate the effects of these interventions on antibiotic consumption., Results: During the 8 year period since establishing EAAD, a 9%-17% decrease in outpatient antibiotic consumption has been observed, depending on the measurement unit, which was a little more than in the 6 years prior to EAAD (7%-12%). The trend change in hospital consumption after EAAD was established remained small, with a highly non-significant P value. Eurobarometer data did not show an increase in knowledge on antibiotic use. Resistance of Streptococcus pneumoniae to penicillin and macrolides decreased during EAAD activities., Conclusions: EAAD activities were associated with a decreasing trend in community consumption. Owing to many other national activities on the prudent use of antimicrobials in outpatients and inpatients it is difficult to analyse the direct effect of EAAD.
- Published
- 2018
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