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Your search keyword '"Voravuthikunchai, Supayang P."' showing total 284 results
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284 results on '"Voravuthikunchai, Supayang P."'

7. Poly (vinyl alcohol) copolymerized with xanthan gum/hypromellose/sodium carboxymethyl cellulose dermal dressings functionalized with biogenic nanostructured materials for antibacterial and wound healing application

Author

Singh, Sudarshan, Nwabor, Ozioma F., Sukri, Dwi M., Wunnoo, Suttiwan, Dumjun, Krittima, Lethongkam, Sakkarin, Kusolphat, Pradipa, Hemtanon, Natthanit, Klinprathum, Keskanok, Sunghan, Jutapoln, Dejyong, Krittee, Lertwittayanon, Kowit, Pisuchpen, Supachai, and Voravuthikunchai, Supayang P.

Published
2022
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17. Rhodomyrtone decreases Staphylococcus aureus SigB activity during exponentially growing phase and inhibits haemolytic activity within membrane vesicles

Author

Jover, A., Barcenilla, F., García, M., Pujol, M., Gasch, O., Domínguez, M.A., Camoez, M., Dueñas, C., Ojeda, E., Martínez, J.A., Marco, F., Chaves, F., Lagarde, M., López-Medrano, F., Montejo, J.M., Bereciertua, E., Hernández, J.L., von Wichmann, M.Á., Goenaga, A., García-Arenzana, J.M., Padilla, B., Padilla, C., Cercenado, E., García-Prado, G., Tapiol, J., Horcajada, J.P., Montero, M., Salvadó, M., Arnáiz, A., Fernández, C., Calbo, E., Xercavins, M., Granados, A., Fontanals, D., Pintado, V., Loza, E., Torre-Cisneros, J., Lara, R., Rodríguez-López, F., Natera, C., Blanco, J.R., Olarte, I., Benito, N., Mirelis, B., Murillas, J., Ruiz de Gopegui, E., Espejo, H., Morera, M.A., Rodríguez-Baño, J., López-Cortés, L.E., Pascual, A., Martín, C., Lepe, J.A., Molina, J., Sordé, R., Almirante, B., Larrosa, N., Mitsuwan, Watcharapong, Jiménez-Munguía, Irene, Visutthi, Monton, Sianglum, Wipawadee, Rodríguez-Ortega, Manuel J., and Voravuthikunchai, Supayang P.

Published
2019
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24. A new alkaloid and a new benzaldehyde derivative from the twig of Zanthoxylum rhetsa (Roxb.) DC

Author

Lookpan, Titiya, Voravuthikunchai, Supayang P., Sitthisuk, Pornnapa, Poorahong, Watcharaporn, Watanapokasin, Ramida, and Chakthong, Suda

Subjects
Organic Chemistry, Plant Science, Biochemistry, Analytical Chemistry
Abstract

A new alkaloid, 2-acetyl-4-methoxyfuro[2,3-b]quinoline (1), and a new benzaldehyde derivative, (2′S)-4-(2′-hydroxy-3′-methyl-3′-butenoxy)benzaldehyde (2), were isolated from the twig of Zanthoxylum rhetsa (Roxb.) DC. along with twenty-six known compounds (3−28). Their structures were determined by spectroscopic analysis (1D and 2D NMR spectroscopy and HRMS analysis) and comparison with data reported in the literature. Thirteen of the known compounds were evaluated for their cytotoxic activities against human cancer cell lines that included MDA-MB-231, SW1353, A549, and HCT116. (±)-8-Acetonyldihydronitidine (15) showed moderate cytotoxicity toward the SW1353 cancer cell line with an IC50 value of 18.90±0.39 µg/mL, and exhibited weak cytotoxic activity against MDA-MB-231, A549 and HCT116 cell lines with IC50 values of 49.86−71.32 µg/mL.

Published
2022

25. A new alkaloid and a new benzaldehyde derivative from the twig of Zanthoxylum rhetsa (Roxb.) DC.

Author

Lookpan, Titiya, Voravuthikunchai, Supayang P., Sitthisuk, Pornnapa, Poorahong, Watcharaporn, Watanapokasin, Ramida, and Chakthong, Suda

Subjects
BENZALDEHYDE, ZANTHOXYLUM, ALKALOIDS, TWIGS, CYTOTOXINS
Abstract

A new alkaloid, 2-acetyl-4-methoxyfuro[2,3-b]quinoline (1), and a new benzaldehyde derivative, (2′S)-4-(2′-hydroxy-3′-methyl-3′-butenoxy)benzaldehyde (2), were isolated from the twig of Zanthoxylum rhetsa (Roxb.) DC. along with twenty-six known compounds (3−28). Their structures were determined by spectroscopic analysis (1D and 2D NMR spectroscopy and HRMS analysis) and comparison with data reported in the literature. Thirteen of the known compounds were evaluated for their cytotoxic activities against human cancer cell lines that included MDA-MB-231, SW1353, A549, and HCT116. (±)-8-Acetonyldihydronitidine (15) showed moderate cytotoxicity toward the SW1353 cancer cell line with an IC50 value of 18.90±0.39 µg/mL, and exhibited weak cytotoxic activity against MDA-MB-231, A549 and HCT116 cell lines with IC50 values of 49.86−71.32 µg/mL. [ABSTRACT FROM AUTHOR]

Published
2024
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26. New acylphloroglucinols from a crude acetone extract of Eucalyptus camaldulensis Dehnh. leaf.

Author

Daus, Mareena, Chakthong, Suda, Dumjun, Krittima, Paosen, Supakit, Voravuthikunchai, Supayang P., Poldorn, Preeyaporn, Jungsuttiwong, Siriporn, Chomlamay, Natharika, Yangok, Kanyaluck, and Watanapokasin, Ramida

Subjects
EUCALYPTUS camaldulensis, BENZENE derivatives, NUCLEAR magnetic resonance, MASS spectrometry, ACETONE, COUMARINS
Abstract

Acylphloroglucinols are well-known Eucalyptus secondary metabolites which exhibit a variety of structures and bioactivities. The investigation of a crude acetone extract of Eucalyptus camaldulensis leaves led to the isolation of two new acylphloroglucinols, eucalypcamals O and P (1 and 2) together with seven phloroglucinols (3–9), and a benzene derivative (10). Their chemical structures were elucidated by 1D and 2D nuclear magnetic resonance (NMR) spectroscopy and mass spectroscopy. The absolute configurations of compounds 1 and 2 were established by comparison of experimental and calculated electronic circular dichroism (ECD) data. In the putative biosynthetic pathway, eucalypcamals O and P should be derived from hetero-Diels-Alder reaction between grandinol and trans-isoeugenol. [ABSTRACT FROM AUTHOR]

Published
2024
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34. Eucalyptus-Mediated Synthesized Silver Nanoparticles-Coated Urinary Catheter Inhibits Microbial Migration and Biofilm Formation

Author

Lethongkam, Sakkarin, primary, Paosen, Supakit, additional, Bilhman, Siwaporn, additional, Dumjun, Krittima, additional, Wunnoo, Suttiwan, additional, Choojit, Suntree, additional, Siri, Ratchaneewan, additional, Daengngam, Chalongrat, additional, Voravuthikunchai, Supayang P., additional, and Bejrananda, Tanan, additional

Published
2022
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37. Isolation and characterisation of bacteriophage selective for key Acinetobacter baumannii capsule chemotypes

Author

Romero-López, Cristina, Soontarach, Rosesathorn, Srimanote, Potjanee, Enright, Mark C, Blundell-Hunter, George, Dorman, Matthew J, Thomson, Nicholas R, Taylor, Peter W, Voravuthikunchai, Supayang P, Romero-López, Cristina, Soontarach, Rosesathorn, Srimanote, Potjanee, Enright, Mark C, Blundell-Hunter, George, Dorman, Matthew J, Thomson, Nicholas R, Taylor, Peter W, and Voravuthikunchai, Supayang P

Abstract

Nineteen bacteriophages against five main capsular types of multidrug-resistant Acinetobacter baumannii were isolated from tertiary care hospital sewage. Eight representative phages from each capsular type were characterized and tested for their biological properties. The biological features revealed that phages T1245, T444, and T515 had a large burst size of more than 420 pfu/mL, together with a short latent period lasting less than 6 min, and were readily adsorbed to a bacterial host within 10 min. Moreover, these phages demonstrated host specificity and stability over a broad range of temperatures (−20 to 60 °C) and pH (5.0–9.0). A whole-genome analysis of six lytic and two temperate phages revealed high genomic similarity with double-stranded DNA between 40 and 50 kb and G + C content of 38–39%. The protein compositions disclosed the absence of toxin-coding genes. The phylogenic results, together with morphological micrographs, confirmed that three selected phages (T1245, T444, and T515) belong to the Podoviridae family within the order Caudovirales. The biological data and bioinformatics analysis indicated that these novel A. baumannii phages possess important enzymes, including depolymerase and endolysin, which could be further developed as promising alternative antibacterial agents to control A. baumannii infections.

Published
2022

38. Successful treatment of refractory erythrodermic psoriasis with traditional Thai herbal medicine.

Author

Siriyong, Thanyaluck, Ontong, Julalak Chorachoo, Khochitmet, Loedlak, Naunklab, Pattarawadee, Phungtammasan, Salinthip, Phrakha, Pimwipa, Chanwanitsakul, Somporn, Terbtothakun, Pawarisa, and Voravuthikunchai, Supayang Piyawan

Abstract

• Traditional Thai herbal formulations were safe and effective in the treatment of erythrodermic psoriasis and had a modest positive impact on the DQLI of the patient. • Successful treatment of erythrodermic psoriasis with Thai herbal formulations was involved in their anti-oxidant and anti-inflammatory activities. • Traditional Thai herbal medicine could be considered as an alternative treatment for refractory erythrodermic psoriasis. Thai herbal formulations have been used traditionally in Thailand for the treatment of psoriasis. However, there is still a lack of scientific data supporting the effects of Thai herbal formulations in psoriasis treatment. This study aimed to demonstrate the therapeutic effects of Thai herbal formulations for the treatment of erythrodermic psoriasis. All Thai herbal formulations (haematic tonic, lymphatic treatment, skin treatment) were obtained from a traditional Thai medicine doctor, Mr. Somporn Chanwanitsakul. The effects of Thai herbal formulations in a patient with erythrodermic psoriasis were assessed for four weeks. Primary outcome, psoriasis area and severity index (PASI) and secondary outcome, safety data and dermatology life quality index (DLQI) measurements were evaluated at baseline and four weeks. Then, in vitro biological activities (antioxidant, anti-microbial, cytotoxic effects, and anti-inflammatory) of Thai herbal formulations were determined to promote the therapeutic effects. Thai herbal formulations were safe and effective in the treatment of erythrodermic psoriasis and had a modest positive impact on the DQLI of the patient. In addition, in vitro studies have shown that all Thai herbal formulations revealed remarkable anti-oxidant and anti-inflammatory potential to support their therapeutic activities. However, the Thai herbal formulations possessed weak intrinsic antibacterial activities against all tested bacterial strains (MIC and MBC E. coli, S. aureus, S. pyogenes, P. aeruginosa : > 256 µg/ml). The findings indicated that successful treatment of erythrodermic psoriasis with Thai herbal formulations was involved in their anti-oxidant and anti-inflammatory activities. They could be considered as an alternative treatment for refractory erythrodermic psoriasis. [ABSTRACT FROM AUTHOR]

Published
2023
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43. New acylphloroglucinols from a crude acetone extract of Eucalyptus camaldulensis Dehnh. leaf

Author

Daus, Mareena, Chakthong, Suda, Dumjun, Krittima, Paosen, Supakit, Voravuthikunchai, Supayang P., Poldorn, Preeyaporn, Jungsuttiwong, Siriporn, Chomlamay, Natharika, Yangok, Kanyaluck, and Watanapokasin, Ramida

Subjects
Organic Chemistry, Plant Science, Biochemistry, Analytical Chemistry
Abstract

Acylphloroglucinols are well-known Eucalyptus secondary metabolites which exhibit a variety of structures and bioactivities. The investigation of a crude acetone extract of Eucalyptus camaldulensis leaves led to the isolation of two new acylphloroglucinols, eucalypcamals O and P (1 and 2) together with seven phloroglucinols (3–9), and a benzene derivative (10). Their chemical structures were elucidated by 1D and 2D nuclear magnetic resonance (NMR) spectroscopy and mass spectroscopy. The absolute configurations of compounds 1 and 2 were established by comparison of experimental and calculated electronic circular dichroism (ECD) data. In the putative biosynthetic pathway, eucalypcamals O and P should be derived from hetero-Diels-Alder reaction between grandinol and trans-isoeugenol.

Published
2022
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49. Nationwide Surveillance and Molecular Characterization of Critically Drug-Resistant Gram-Negative Bacteria: Results of the Research University Network Thailand Study

Author

Yungyuen, Thitiya, primary, Chatsuwan, Tanittha, additional, Plongla, Rongpong, additional, Kanthawong, Sakawrat, additional, Yordpratum, Umaporn, additional, Voravuthikunchai, Supayang P., additional, Chusri, Sarunyou, additional, Saeloh, Dennapa, additional, Samosornsuk, Worada, additional, Suwantarat, Nuntra, additional, Chaiwarith, Romanee, additional, Wannalerdsakun, Surat, additional, Rotjanapan, Porpon, additional, Chantharit, Prawat, additional, Tulyaprawat, Orawan, additional, Thaipisuttikul, Iyarit, additional, and Kiratisin, Pattarachai, additional

Published
2021
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