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13 results on '"Volpi, Marina"'

4. Alginate-based tissue-specific bioinks for multi-material 3D-bioprinting of pancreatic islets and blood vessels: A step towards vascularized pancreas grafts

Author

Idaszek, Joanna, Volpi, Marina, Paradiso, Alessia, Nguyen Quoc, Martyna, Górecka, Żaneta, Klak, Marta, Tymicki, Grzegorz, Berman, Andrzej, Wierzbicki, Mateusz, Jaworski, Sławomir, Costantini, Marco, Kępczyńska, Agnieszka, Chwalibóg, Ewa Sawosz, Wszoła, Michał, and Święszkowski, Wojciech

Published
2021
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5. Combining rotary wet-spinning biofabrication and electro-mechanical stimulation for the in vitro production of functional myo-substitutes

Author

Celikkin, Nehar, primary, Presutti, Dario, additional, Maiullari, Fabio, additional, Volpi, Marina, additional, Promovych, Yurii, additional, Gizynski, Konrad, additional, Dolinska, Joanna, additional, Wiśniewska, Agnieszka, additional, Opałło, Marcin, additional, Paradiso, Alessia, additional, Rinoldi, Chiara, additional, Fuoco, Claudia, additional, Swieszkowski, Wojciech, additional, Bearzi, Claudia, additional, Rizzi, Roberto, additional, Gargioli, Cesare, additional, and Costantini, Marco, additional

Published
2023
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7. Microfluidic 3D Printing of Emulsion Ink for Engineering Porous Functionally Graded Materials

Author

Marcotulli, Martina, primary, Tirelli, Maria Celeste, additional, Volpi, Marina, additional, Jaroszewicz, Jakub, additional, Scognamiglio, Chiara, additional, Kasprzycki, Piotr, additional, Karnowski, Karol, additional, Święszkowski, Wojciech, additional, Ruocco, Giancarlo, additional, Costantini, Marco, additional, Cidonio, Gianluca, additional, and Barbetta, Andrea, additional

Published
2022
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8. Microfluidic 3D Printing of Emulsion Ink for Engineering Porous Functionally Graded Materials.

Author

Marcotulli, Martina, Tirelli, Maria Celeste, Volpi, Marina, Jaroszewicz, Jakub, Scognamiglio, Chiara, Kasprzycki, Piotr, Karnowski, Karol, Święszkowski, Wojciech, Ruocco, Giancarlo, Costantini, Marco, Cidonio, Gianluca, and Barbetta, Andrea

Subjects
FUNCTIONALLY gradient materials, THREE-dimensional printing, PRINTING ink, ENGINEERING, SEED technology, POROUS materials, EMULSIONS
Abstract

In the last decade, 3D printing systems have greatly evolved both in terms of processable materials and printing resolutions, becoming a top seed technology for many academic and industrial applications. Nevertheless, manufacturing polymeric materials characterized by a trabecular porosity and functionally graded architecture—where both the local porosity and chemical composition of the matrix change in the 3D space—through additive platforms remains an open technical challenge. In this study, a 3D extrusion printing strategy to tackle this problem is presented. The proposed systems are based on a flow‐focusing microfluidic printing head—to continuously generate oil‐in‐water emulsion inks—and on an agarose fluid–gel used as a temporary support bath for the deposition of the photo‐curable emulsion inks. It is demonstrated that through this strategy one can design a priori and build with high accuracy both discontinuous and continuous functionally graded polymeric foams, where both the density and composition of the materials could be varied independently within arbitrarily complex 3D architectures. This study provides new means for the synthesis of microporous, polymeric FGMs which could find applications ranging from interface tissue engineering to automotive and construction industries. [ABSTRACT FROM AUTHOR]

Published
2023
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10. Tackling Current Biomedical Challenges With Frontier Biofabrication and Organ-On-A-Chip Technologies

Author

Celikkin, Nehar, primary, Presutti, Dario, additional, Maiullari, Fabio, additional, Fornetti, Ersilia, additional, Agarwal, Tarun, additional, Paradiso, Alessia, additional, Volpi, Marina, additional, Święszkowski, Wojciech, additional, Bearzi, Claudia, additional, Barbetta, Andrea, additional, Zhang, Yu Shrike, additional, Gargioli, Cesare, additional, Rizzi, Roberto, additional, and Costantini, Marco, additional

Published
2021
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11. Tumor Extracellular Matrix Stiffness Promptly Modulates the Phenotype and Gene Expression of Infiltrating T Lymphocytes

Author

Chirivì, Maila, primary, Maiullari, Fabio, additional, Milan, Marika, additional, Presutti, Dario, additional, Cordiglieri, Chiara, additional, Crosti, Mariacristina, additional, Sarnicola, Maria Lucia, additional, Soluri, Andrea, additional, Volpi, Marina, additional, Święszkowski, Wojciech, additional, Prati, Daniele, additional, Rizzi, Marta, additional, Costantini, Marco, additional, Seliktar, Dror, additional, Parisi, Chiara, additional, Bearzi, Claudia, additional, and Rizzi, Roberto, additional

Published
2021
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12. In vitrofunctional models for human liver diseases and drug screening: beyond animal testing

Author

Paradiso, Alessia, Volpi, Marina, Rinoldi, Chiara, Celikkin, Nehar, Contessi Negrini, Nicola, Bilgen, Muge, Dallera, Giorgio, Pierini, Filippo, Costantini, Marco, wiszkowski, Wojciech, and Farè, Silvia

Abstract

Liver is one of the most important and complex organs in the human body, being characterized by a sophisticated microarchitecture and responsible for key physiological functions. Despite its remarkable ability to regenerate, acute liver failure and chronic liver diseases are major causes of morbidity and mortality worldwide. Therefore, understanding the molecular mechanisms underlying such liver disorders is critical for the successful development of novel therapeutics. In this frame, preclinical animal models have been portrayed as the most commonly used tool to address such issues. However, due to significant species differences in liver architecture, regenerative capacity, disease progression, inflammatory markers, metabolism rates, and drug response, animal models cannot fully recapitulate the complexity of human liver metabolism. As a result, translational research to model human liver diseases and drug screening platforms may yield limited results, leading to failure scenarios. To overcome this impasse, over the last decade, 3D human liver in vitromodels have been proposed as an alternative to pre-clinical animal models. These systems have been successfully employed for the investigation of the etiology and dynamics of liver diseases, for drug screening, and – more recently – to design patient-tailored therapies, resulting in potentially higher efficacy and reduced costs compared to other methods. Here, we review the most recent advances in this rapidly evolving field with particular attention to organoid cultures, liver-on-a-chip platforms, and engineered scaffold-based approaches.

Published
2023
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