Search

Your search keyword '"Vlasselaers, Dirk"' showing total 245 results
Start Over Author "Vlasselaers, Dirk"
245 results on '"Vlasselaers, Dirk"'

1. Intermittent intravenous paracetamol versus continuous morphine in infants undergoing cardiothoracic surgery: a multi-center randomized controlled trial

Author

Zeilmaker-Roest, Gerdien, de Vries-Rink, Christine, van Rosmalen, Joost, van Dijk, Monique, de Wildt, Saskia N., Knibbe, Catherijne A. J., Koomen, Erik, Jansen, Nicolaas J. G., Kneyber, Martin C. J., Maebe, Sofie, Van den Berghe, Greet, Haghedooren, Renata, Vlasselaers, Dirk, Bogers, Ad J. J. C., Tibboel, Dick, and Wildschut, Enno D.

Published
2024
Full Text
View/download PDF

3. Management of Bleeding and Hemolysis During Percutaneous Microaxial Flow Pump Support: A Practical Approach

Author

Van Edom, Charlotte J., Gramegna, Mario, Baldetti, Luca, Beneduce, Alessandro, Castelein, Thomas, Dauwe, Dieter, Frederiks, Pascal, Giustino, Gennaro, Jacquemin, Marc, Janssens, Stefan P., Panoulas, Vasileios F., Pöss, Janine, Rosenberg, Alexander, Schaubroeck, Hannah A.I., Schrage, Benedikt, Tavazzi, Guido, Vanassche, Thomas, Vercaemst, Leen, Vlasselaers, Dirk, Vranckx, Pascal, Belohlavek, Jan, Gorog, Diana A., Huber, Kurt, Mebazaa, Alexandre, Meyns, Bart, Pappalardo, Federico, Scandroglio, Anna M., Stone, Gregg W., Westermann, Dirk, Chieffo, Alaide, Price, Susanna, and Vandenbriele, Christophe

Published
2023
Full Text
View/download PDF

5. Leukocyte telomere length in paediatric critical illness: effect of early parenteral nutrition.

Author

Verstraete, Sören, Vanhorebeek, Ilse, van Puffelen, Esther, Derese, Inge, Ingels, Catherine, Verbruggen, Sascha, Wouters, Pieter, Joosten, Koen, Hanot, Jan, Guerra, Gonzalo, Vlasselaers, Dirk, Lin, Jue, and Van den Berghe, Greet

Subjects
Children, Critical care, Critical illness, Intensive care, Nutrition, PICU, Paediatric, Telomere length, Telomeres, Adolescent, Child, Child, Preschool, Critical Illness, Female, Humans, Infant, Intensive Care Units, Pediatric, Leukocytes, Male, Parenteral Nutrition, Pediatrics, Propensity Score, Survival Analysis, Telomere, Time Factors
Abstract

BACKGROUND: Children who have suffered from critical illnesses that required treatment in a paediatric intensive care unit (PICU) have long-term physical and neurodevelopmental impairments. The mechanisms underlying this legacy remain largely unknown. In patients suffering from chronic diseases hallmarked by inflammation and oxidative stress, poor long-term outcome has been associated with shorter telomeres. Shortened telomeres have also been reported to result from excessive food consumption and/or unhealthy nutrition. We investigated whether critically ill children admitted to the PICU have shorter-than-normal telomeres, and whether early parenteral nutrition (PN) independently affects telomere length when adjusting for known determinants of telomere length. METHODS: Telomere length was quantified in leukocyte DNA from 342 healthy children and from 1148 patients who had been enrolled in the multicenter, randomised controlled trial (RCT), PEPaNIC. These patients were randomly allocated to initiation of PN within 24 h (early PN) or to withholding PN for one week in PICU (late PN). The impact of early PN versus late PN on the change in telomere length from the first to last PICU-day was investigated with multivariable linear regression analyses. RESULTS: Leukocyte telomeres were 6% shorter than normal upon PICU admission (median 1.625 (IQR 1.446-1.825) telomere/single-copy-gene ratio (T/S) units vs. 1.727 (1.547-1.915) T/S-units in healthy children (P

Published
2018

6. Supplementation of vitamins, trace elements and electrolytes in the PEPaNIC Randomised Controlled Trial: Composition and preparation of the prescription

Author

Eveleens, Renate D., Witjes, Bregje C.M., Casaer, Michael P., Vanhorebeek, Ilse, Guerra, Gonzalo Garcia, Veldscholte, Karlien, Hanff, Lidwien M., Cosaert, Katrien, Desmet, Lars, Vlasselaers, Dirk, Maebe, Sofie, Bernard, Britney, Van den Berghe, Greet, Verbruggen, Sascha C.A.T., and Joosten, Koen F.M.

Published
2021
Full Text
View/download PDF

7. Intermittent intravenous paracetamol versus continuous morphine in infants undergoing cardiothoracic surgery: a multi-center randomized controlled trial

Author

Intensive care patientenzorg, Cluster A, Zeilmaker-Roest, Gerdien, de Vries-Rink, Christine, van Rosmalen, Joost, van Dijk, Monique, de Wildt, Saskia N., Knibbe, Catherijne A.J., Koomen, Erik, Jansen, Nicolaas J.G., Kneyber, Martin C.J., Maebe, Sofie, Van den Berghe, Greet, Haghedooren, Renata, Vlasselaers, Dirk, Bogers, Ad J.J.C., Tibboel, Dick, Wildschut, Enno D., Intensive care patientenzorg, Cluster A, Zeilmaker-Roest, Gerdien, de Vries-Rink, Christine, van Rosmalen, Joost, van Dijk, Monique, de Wildt, Saskia N., Knibbe, Catherijne A.J., Koomen, Erik, Jansen, Nicolaas J.G., Kneyber, Martin C.J., Maebe, Sofie, Van den Berghe, Greet, Haghedooren, Renata, Vlasselaers, Dirk, Bogers, Ad J.J.C., Tibboel, Dick, and Wildschut, Enno D.

Published
2024

8. Intermittent intravenous paracetamol versus continuous morphine in infants undergoing cardiothoracic surgery:a multi-center randomized controlled trial

Author

Zeilmaker-Roest, Gerdien, de Vries-Rink, Christine, van Rosmalen, Joost, van Dijk, Monique, de Wildt, Saskia N., Knibbe, Catherijne A.J., Koomen, Erik, Jansen, Nicolaas J.G., Kneyber, Martin C.J., Maebe, Sofie, Van den Berghe, Greet, Haghedooren, Renata, Vlasselaers, Dirk, Bogers, Ad J.J.C., Tibboel, Dick, Wildschut, Enno D., Zeilmaker-Roest, Gerdien, de Vries-Rink, Christine, van Rosmalen, Joost, van Dijk, Monique, de Wildt, Saskia N., Knibbe, Catherijne A.J., Koomen, Erik, Jansen, Nicolaas J.G., Kneyber, Martin C.J., Maebe, Sofie, Van den Berghe, Greet, Haghedooren, Renata, Vlasselaers, Dirk, Bogers, Ad J.J.C., Tibboel, Dick, and Wildschut, Enno D.

Abstract

Background: To determine whether intermittent intravenous (IV) paracetamol as primary analgesic would significantly reduce morphine consumption in children aged 0–3 years after cardiac surgery with cardiopulmonary bypass. Methods: Multi-center, randomized, double-blinded, controlled trial in four level-3 Pediatric Intensive Care Units (PICU) in the Netherlands and Belgium. Inclusion period; March 2016–July 2020. Children aged 0–3 years, undergoing cardiac surgery with cardiopulmonary bypass were eligible. Patients were randomized to continuous morphine or intermittent IV paracetamol as primary analgesic after a loading dose of 100 mcg/kg morphine was administered at the end of surgery. Rescue morphine was given if numeric rating scale (NRS) pain scores exceeded predetermined cutoff values. Primary outcome was median weight-adjusted cumulative morphine dose in mcg/kg in the first 48 h postoperative. For the comparison of the primary outcome between groups, the nonparametric Van Elteren test with stratification by center was used. For comparison of the proportion of patients with one or more NRS pain scores of 4 and higher between the two groups, a non-inferiority analysis was performed using a non-inferiority margin of 20%. Results:In total, 828 were screened and finally 208 patients were included; parents of 315 patients did not give consent and 305 were excluded for various reasons. Fourteen of the enrolled 208 children were withdrawn from the study before start of study medication leaving 194 patients for final analysis. One hundred and two patients received intermittent IV paracetamol, 106 received continuous morphine. The median weight-adjusted cumulative morphine consumption in the first 48 h postoperative in the IV paracetamol group was 5 times lower (79%) than that in the morphine group (median, 145.0 (IQR, 115.0–432.5) mcg/kg vs 692.6 (IQR, 532.7–856.1) mcg/kg; P < 0.001). The rescue morphine cons

Published
2024

9. Intermittent intravenous paracetamol versus continuous morphine in infants undergoing cardiothoracic surgery: a multi-center randomized controlled trial

Author

Zeilmaker-Roest, Gerdien, primary, de Vries-Rink, Christine, additional, Rosmalen, Joost van, additional, Dijk, Monique van, additional, de Wildt, Saskia N., additional, Knibbe, Catherijne A. J., additional, Koomen, Erik, additional, Jansen, Nicolaas J. G., additional, Kneyber, Martin C. J., additional, Maebe, Sofie, additional, Berghe, Greet van den, additional, Haghedooren, Renata, additional, Vlasselaers, Dirk, additional, Bogers, Ad J.J.C., additional, Tibboel, Dick, additional, and Wildschut, Enno D., additional

Published
2024
Full Text
View/download PDF

10. Successful clinical transplantation of hearts donated after circulatory death using direct procurement followed by hypothermic oxygenated perfusion: A report of the first 3 cases

Author

Brouckaert, Janne, Vandendriessche, Katrien, Degezelle, Karlien, Van de Voorde, Kristof, De Burghgraeve, Francis, Desmet, Lars, Vlasselaers, Dirk, Ingels, Catherine, Dauwe, Dieter, De Troy, Erwin, Ceulemans, Laurens J., Van Raemdonck, Dirk, Monbaliu, Diethard, Meyns, Bart, Van den Eynde, Raf, Rex, Steffen, Van Cleemput, Johan, and Rega, Filip

Published
2024
Full Text
View/download PDF

12. Tight Blood-Glucose Control without Early Parenteral Nutrition in the ICU

Author

Gunst, Jan, primary, Debaveye, Yves, additional, Güiza, Fabian, additional, Dubois, Jasperina, additional, De Bruyn, Astrid, additional, Dauwe, Dieter, additional, De Troy, Erwin, additional, Casaer, Michael P., additional, De Vlieger, Greet, additional, Haghedooren, Renata, additional, Jacobs, Bart, additional, Meyfroidt, Geert, additional, Ingels, Catherine, additional, Muller, Jan, additional, Vlasselaers, Dirk, additional, Desmet, Lars, additional, Mebis, Liese, additional, Wouters, Pieter J., additional, Stessel, Björn, additional, Geebelen, Laurien, additional, Vandenbrande, Jeroen, additional, Brands, Michiel, additional, Gruyters, Ine, additional, Geerts, Ester, additional, De Pauw, Ilse, additional, Vermassen, Joris, additional, Peperstraete, Harlinde, additional, Hoste, Eric, additional, De Waele, Jan J., additional, Herck, Ingrid, additional, Depuydt, Pieter, additional, Wilmer, Alexander, additional, Hermans, Greet, additional, Benoit, Dominique D., additional, and Van den Berghe, Greet, additional

Published
2023
Full Text
View/download PDF

14. Endovascular transatrial stenting of pulmonary vein stenosis after lung transplantation

Author

Orlitová, Michaela, primary, Gewillig, Marc, additional, Van Slambrouck, Jan, additional, Vlasselaers, Dirk, additional, Jacobs, Bart, additional, Neyrinck, Arne P., additional, Depypere, Lieven, additional, Godinas, Laurent, additional, Vos, Robin, additional, Verleden, Geert M., additional, Van Raemdonck, Dirk E., additional, and Ceulemans, Laurens J., additional

Published
2023
Full Text
View/download PDF

15. The Health and Care Professions of the Future

Author

Schokkaert, Erik, Aerts, JM, Callens, Stefaan, Eggermont, Jan, Foulon, Veerle, Moons, Philip, Noens, Ilse, Rademakers, Frank, Van Assche, Dieter, Vandenhoeck, Anne, Vander Sloten, Jos, Van Hootegem, Geert, Van Huffel, Sabine, Verbakel, Jan, Vlasselaers, Dirk, and Achten, Veerle

Abstract

ispartof: pages:1-112 status: published

Published
2023

19. ECMO for COVID-19 patients in Europe and Israel

Author

Lorusso, Roberto, Combes, Alain, Coco, Valeria Lo, De Piero, Maria Elena, Belohlavek, Jan, Delnoij, Thijs, van der Horst, Iwan, Miranda, Dinis Reis, van der Linden, Marcel, van der Heijden, JJ, Scholten, Erik, van Belle-van Haren, Nicole, Lagrand, Wim, de Jong, Sytse, Candura, Dario, Maas, Jacinta, van den Berg, MJ van Gijlswijk, Malfertheiner, Maximilian, Dreier, Esther, Mueller, Thomas, Boeken, Udo, Akhyari, Payam, Lichtenberg, Artur, Saeed, Diyar, Thiele, Holger, Baumgaertel, Matthias, Schmitto, Jan D, Mariani, Silvia, Thielmann, Matthias, Brenner, Thorsten, Benk, Cristoph, Czerny, Martin, Kalbhenn, Johannes, Maier, Sven, Schibilsky, David, Staudacher, Dawid L, Henn, Philipp, Iuliu, Torje, Muellenbach, Ralf, Reyher, Christian, Rolfes, Caroline, Zacharowski, Kai, Lotz, Gosta, Sonntagbauer, Michael, Kersten, Alexander, Karagiannidis, Christian, Schafer, Simone, Fichte, Julia, Hopf, Hans-Bernd, Samalavicius, Robertas, Lorini, Luca, Ghitti, Davide, Grazioli, Lorenzo, Loforte, Antonio, Baiocchi, Massimo, Checco, Erika Dal, Pacini, Davide, Meani, Paolo, Cappai, Antioco, Russo, Claudio Francesco, Bottiroli, Maurizio, Mondino, Michele, Ranucci, Marco, Fina, Dario, Ballotta, Andrea, Scandroglio, Anna Mara, Zangrillo, Alberto, Pieri, Marina, Nardelli, Pasquale, Fominskiy, Evgeny, Landoni, Giovanni, Fanelli, Vito, Brazzi, Luca, Montrucchio, Giorgia, Sales, Gabriele, Simonetti, Umberto, Urbino, Rosario, Livigni, Sergio, Degani, Antonella, Raffa, Giuseppe, Pilato, Michele, Martucci, Gennaro, Arcadipane, Antonio, Chiarini, Giovanni, Latronico, Nicola, Cattaneo, Sergio, Puglia, Carmine, Reina, Gianfranco, Sponga, Sandro, Livi, Ugolino, Foti, Giuseppe, Giani, Marco, Rona, Roberto, Avalli, Leonello, Bombino, Michela, Costa, Maria Cristina, Carozza, Roberto, Donati, Abele, Piciche, Marco, Favaro, Alessandro, Salvador, Loris, Danzi, Vinicio, Zanin, Anita, Condello, Ignazio, Fiore, Flavio, Moscarelli, Marco, Nasso, Giuseppe, Speziale, Giuseppe, Sandrelli, Luca, Montalto, Andrea, Musumeci, Francesco, Circelli, Alessandro, Gamberini, Emiliano, Russo, Emanuele, Benni, Marco, Agnoletti, Vanni, Rociola, Ruggero, Milano, Aldo D, Grasso, Salvatore, Civita, Antonio, Murgolo, Francesco, Pilato, Emanuele, Comentale, Giuseppe, Montisci, Andrea, Alessandri, Francesco, Tosi, Antonella, Pugliese, Francesco, Carelli, Simone, Grieco, Domenico Luca, Antonelli, Massimo, Ramoni, Enrico, Di Nardo, Matteo, Maisano, Francesco, Bettex, Dominique, Weber, Alberto, Grunenfelder, Jurg, Consiglio, Jolanda, Hansjoerg, Jenni, Haenggi, Matthias, Agus, Gianluca, Doeble, Thomas, Zenklusen, Urs, Bechtold, Xavier, Stockman, Bernard, De Backer, Daniel, Giglioli, Simone, Meyns, Bart, Vercaemst, Leen, Herman, Greet, Meersseman, Philippe, Vandenbriele, Christophe, Dauwe, Dieter, Vlasselaers, Dirk, Raes, Matthias, Debeuckelaere, Gerdy, Rodrigus, Inez, Biston, Patrick, Piagnerelli, Michael, Peperstraete, Harlinde, Germay, Olivier, Vandewiele, Korneel, Vandeweghe, Dimitri, Witters, Ine, Havrin, Sven, Bourgeois, Marc, Taccone, Fabio Silvio, Nobile, Leda, Lheureux, Olivier, Brasseur, Alexandre, Creteur, Jacques, Defraigne, Jean-Olivier, Misset, Benoit, Courcelle, Romain, Timmermans, Philippe, Lehaen, Jeroen, Frederik, Bonte, Riera, Jordi, Castro, Miguel angel, Gallart, Elisabet, Martinez-Martinez, Maria, Argudo, Eduard, Garcia-de-Acilu, Marina, de Pablo Sanchez, Raul, Ortiz, Aaron Blandino, Cabanes, Mari-Paz Fuset, Higa, Karina Osorio, Cassina, Albert Miralles, Berbel, Daniel Ortiz, Sanchez-Salado, Jose Carlos, Arnau, Blasco-Lucas, de Gopegui, Pablo Ruiz, Ricart, Pilar, Sandoval, Elena, Veganzones, Javier, Millan, Pablo, de la Sota, Perez, Santa Teresa, Patricia, Alcantara, Sara, Alvarez, Jorge Duerto, Gonzalez, Anxela Vidal, Lopez, Marta, Gordillo, Antonio, Naranjo-Izurieta, Jose, Costa, Ricardo Gimeno, Albacete Moreno, Carlos L, de Ayala, Jose angel, Blanco-Schweizer, Pablo, Andres, Nicolas Hidalgo, Boado, Victoria, Martinez, Jose Maria Nunez, Casal, Vanesa Gomez, Garcia, Esperanza Fernandez, Martin-Villen, Luis, Climent, Joaquin Colomina, Pinto, Luis F, Leprince, Pascal, Lebreton, Guillaume, Juvin, Charles, Schmidt, Matthieu, Pineton, Marc, Folliguet, Thierry, Saiydoun, Gabriel, Gaudard, Philippe, Colson, Pascal, Obadia, Jean-Francois, Pozzi, Matteo, Fellahi, Jean Luc, Yonis, Hodane, Richard, Jean Christophe, Parasido, Alessandro, Verhoye, Jean-Philippe, Flecher, Erwan, Ajrhourh, Lucrezia, Nesseler, Nicolas, Mansour, Alexandre, Guinot, Pierre-Gregoire, Zarka, Jonathan, Besserve, Patricia, Makhoul, Maged, Bolotin, Gil, Kassif, Yigal, Soufleris, Dimitros, Schellongowski, Peter, Bonaros, Nikolaos, Krapf, Christoph, Ebert, Kathrin, Mair, Peter, Kothleutner, Florian, Kowalewsky, Mariusz, Christensen, Steffen, Pedersen, Finn Moller, Balik, Martin, Blaha, Jan, Lips, Michal, Otahal, Michal, Camporota, Luigi, Daly, Kathleen, Agnew, Nicola, Barker, Julian, Head, Laura, Garcia, Miguel, Ledot, Stephane, Aquino, Verna, Lewis, Rebecca, Worthy, Jennifer, Noor, Hamza, Scott, Ian, O'Brien, Serena, Conrick-Martin, Ian, Carton, Edmund, Gillon, Stuart, Flemming, Lucy, Broman, Lars Mikael, Grins, Edgars, Ketskalo, Michail, Tsarenko, Sergey, Popugaev, Konstantin, Minin, Sergei, Kornilov, Igor, Skopets, Alexander, Kornelyuk, Roman, Turchaninov, Alexandr, Gorjup, Vojka, Shelukhin, Daniil, Dsouki, Youssef El, Sargin, Murat, Kaygin, Mehmet Ali, Liana, Shestakova, Puss, Severin, Soerensen, Gro, Magnus, Rosen, Kanetoft, Mikael, Watson, Pia, Redfors, Bengt, Krenner, Niklas, Velia Antonini, M, Barrett, Nicholas A, Belliato, Mirko, Davidson, Mark, Finney, Simon, Fowles, Jo-Anne, Halbe, Maximilian, Hennig, Felix, Jones, Tim, Pinto, Luis, Smith, Jonathan, Roeleveld, Peter, Swol, Justyna, Maastricht University Medical Centre (MUMC), Maastricht University [Maastricht], Cardiovascular Research Institute Maastricht (CARIM), CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Sorbonne Université - Faculté de Médecine (SU FM), Sorbonne Université (SU), First Faculty of Medicine Charles University [Prague], Intensive Care Medicine, AII - Inflammatory diseases, ANS - Neuroinfection & -inflammation, EuroECMO COVID-19 Working Group, Euro-ELSO Steering Committee, Lorusso, Roberto, Combes, Alain, Coco, Valeria Lo, De Piero, Maria Elena, Belohlavek, Jan (EuroECMO COVID-19, Workinggroup, Euro-ELSO Steering, Committee), Zangrillo, A, Landoni, G, CTC, MUMC+: MA Med Staf Spec CTC (9), RS: Carim - V04 Surgical intervention, MUMC+: MA Alg Ond Onderz CTC (9), Lorusso, R, Combes, A, Coco, V, De Piero, M, Belohlavek, J, Delnoij, T, van der Horst, I, Miranda, D, van der Linden, M, van der Heijden, J, Scholten, E, van Belle-van Haren, N, Lagrand, W, de Jong, S, Candura, D, Maas, J, van den Berg, M, Malfertheiner, M, Dreier, E, Mueller, T, Boeken, U, Akhyari, P, Lichtenberg, A, Saeed, D, Thiele, H, Baumgaertel, M, Schmitto, J, Mariani, S, Thielmann, M, Brenner, T, Benk, C, Czerny, M, Kalbhenn, J, Maier, S, Schibilsky, D, Staudacher, D, Henn, P, Iuliu, T, Muellenbach, R, Reyher, C, Rolfes, C, Zacharowski, K, Lotz, G, Sonntagbauer, M, Kersten, A, Karagiannidis, C, Schafer, S, Fichte, J, Hopf, H, Samalavicius, R, Lorini, L, Ghitti, D, Grazioli, L, Loforte, A, Baiocchi, M, Checco, E, Pacini, D, Meani, P, Cappai, A, Russo, C, Bottiroli, M, Mondino, M, Ranucci, M, Fina, D, Ballotta, A, Scandroglio, A, Pieri, M, Nardelli, P, Fominskiy, E, Fanelli, V, Brazzi, L, Montrucchio, G, Sales, G, Simonetti, U, Urbino, R, Livigni, S, Degani, A, Raffa, G, Pilato, M, Martucci, G, Arcadipane, A, Chiarini, G, Latronico, N, Cattaneo, S, Puglia, C, Reina, G, Sponga, S, Livi, U, Foti, G, Giani, M, Rona, R, Avalli, L, Bombino, M, Costa, M, Carozza, R, Donati, A, Piciche, M, Favaro, A, Salvador, L, Danzi, V, Zanin, A, Condello, I, Fiore, F, Moscarelli, M, Nasso, G, Speziale, G, Sandrelli, L, Montalto, A, Musumeci, F, Circelli, A, Gamberini, E, Russo, E, Benni, M, Agnoletti, V, Rociola, R, Milano, A, Grasso, S, Civita, A, Murgolo, F, Pilato, E, Comentale, G, Montisci, A, Alessandri, F, Tosi, A, Pugliese, F, Carelli, S, Grieco, D, Antonelli, M, Ramoni, E, Di Nardo, M, Maisano, F, Bettex, D, Weber, A, Grunenfelder, J, Consiglio, J, Hansjoerg, J, Haenggi, M, Agus, G, Doeble, T, Zenklusen, U, Bechtold, X, Stockman, B, De Backer, D, Giglioli, S, Meyns, B, Vercaemst, L, Herman, G, Meersseman, P, Vandenbriele, C, Dauwe, D, Vlasselaers, D, Raes, M, Debeuckelaere, G, Rodrigus, I, Biston, P, Piagnerelli, M, Peperstraete, H, Germay, O, Vandewiele, K, Vandeweghe, D, Witters, I, Havrin, S, Bourgeois, M, Taccone, F, Nobile, L, Lheureux, O, Brasseur, A, Creteur, J, Defraigne, J, Misset, B, Courcelle, R, Timmermans, P, Lehaen, J, Frederik, B, Riera, J, Castro, M, Gallart, E, Martinez-Martinez, M, Argudo, E, Garcia-de-Acilu, M, de Pablo Sanchez, R, Ortiz, A, Cabanes, M, Higa, K, Cassina, A, Berbel, D, Sanchez-Salado, J, Arnau, B, de Gopegui, P, Ricart, P, Sandoval, E, Veganzones, J, Millan, P, de la Sota, P, Santa Teresa, P, Alcantara, S, Alvarez, J, Gonzalez, A, Lopez, M, Gordillo, A, Naranjo-Izurieta, J, Costa, R, Albacete Moreno, C, de Ayala, J, Blanco-Schweizer, P, Andres, N, Boado, V, Martinez, J, Casal, V, Garcia, E, Martin-Villen, L, Climent, J, Pinto, L, Leprince, P, Lebreton, G, Juvin, C, Schmidt, M, Pineton, M, Folliguet, T, Saiydoun, G, Gaudard, P, Colson, P, Obadia, J, Pozzi, M, Fellahi, J, Yonis, H, Richard, J, Parasido, A, Verhoye, J, Flecher, E, Ajrhourh, L, Nesseler, N, Mansour, A, Guinot, P, Zarka, J, Besserve, P, Makhoul, M, Bolotin, G, Kassif, Y, Soufleris, D, Schellongowski, P, Bonaros, N, Krapf, C, Ebert, K, Mair, P, Kothleutner, F, Kowalewsky, M, Christensen, S, Pedersen, F, Balik, M, Blaha, J, Lips, M, Otahal, M, Camporota, L, Daly, K, Agnew, N, Barker, J, Head, L, Garcia, M, Ledot, S, Aquino, V, Lewis, R, Worthy, J, Noor, H, Scott, I, O'Brien, S, Conrick-Martin, I, Carton, E, Gillon, S, Flemming, L, Broman, L, Grins, E, Ketskalo, M, Tsarenko, S, Popugaev, K, Minin, S, Kornilov, I, Skopets, A, Kornelyuk, R, Turchaninov, A, Gorjup, V, Shelukhin, D, Dsouki, Y, Sargin, M, Kaygin, M, Liana, S, Puss, S, Soerensen, G, Magnus, R, Kanetoft, M, Watson, P, Redfors, B, Krenner, N, Velia Antonini, M, Barrett, N, Belliato, M, Davidson, M, Finney, S, Fowles, J, Halbe, M, Hennig, F, Jones, T, Smith, J, Roeleveld, P, Swol, J, Lorusso R., Combes A., Coco V.L., De Piero M.E., and Belohlavek J, EuroECMO COVID-19 WorkingGroup, and Euro-ELSO Steering Committee, Pacini D

Subjects
2019-20 coronavirus outbreak, medicine.medical_specialty, Letter, Coronavirus disease 2019 (COVID-19), Pain medicine, medicine.medical_treatment, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), [SDV]Life Sciences [q-bio], MEDLINE, 610 Medicine & health, 030204 cardiovascular system & hematology, Critical Care and Intensive Care Medicine, 03 medical and health sciences, Extracorporeal Membrane Oxygenation, covid, ecmo, respiratory failure, 0302 clinical medicine, Critical Care Medicine, General & Internal Medicine, Anesthesiology, medicine, Extracorporeal membrane oxygenation, Humans, Israel, ComputingMilieux_MISCELLANEOUS, Science & Technology, business.industry, COVID-19, 030208 emergency & critical care medicine, 3. Good health, Europe, Emergency medicine, Human medicine, ECMO, business, Life Sciences & Biomedicine, Human
Abstract

ispartof: INTENSIVE CARE MEDICINE vol:47 issue:3 pages:344-348 ispartof: location:United States status: published

Published
2021

21. International survey of neuromonitoring and neurodevelopmental outcome in children and adults supported on extracorporeal membrane oxygenation in Europe.

Author

Cvetkovic, Mirjana, Chiarini, Giovanni, Belliato, Mirko, Delnoij, Thijs, Zanatta, Paolo, Taccone, Fabio Silvio, Miranda, Dinis dos Reis, Davidson, Mark, Matta, Nashwa, Davis, Carl, IJsselstijn, Hanneke, Schmidt, Matthieu, Broman, Lars Mikael, Donker, Dirk W, Vlasselaers, Dirk, David, Piero, Di Nardo, Matteo, Muellenbach, Ralf M, Mueller, Thomas, and Barrett, Nicholas A

Subjects
BIOMARKERS, INTERNATIONAL relations, ELECTROENCEPHALOGRAPHY, EXTRACORPOREAL membrane oxygenation, TRANSCRANIAL Doppler ultrasonography, NEURAL development, PATIENT monitoring, PEARSON correlation (Statistics), QUESTIONNAIRES, DESCRIPTIVE statistics, BRAIN injuries, DATA analysis software, LONGITUDINAL method, NEURORADIOLOGY
Abstract

Background: Adverse neurological events during extracorporeal membrane oxygenation (ECMO) are common and may be associated with devastating consequences. Close monitoring, early identification and prompt intervention can mitigate early and late neurological morbidity. Neuromonitoring and neurocognitive/neurodevelopmental follow-up are critically important to optimize outcomes in both adults and children. Objective: To assess current practice of neuromonitoring during ECMO and neurocognitive/neurodevelopmental follow-up after ECMO across Europe and to inform the development of neuromonitoring and follow-up guidelines. Methods: The EuroELSO Neurological Monitoring and Outcome Working Group conducted an electronic, web-based, multi-institutional, multinational survey in Europe. Results: Of the 211 European ECMO centres (including non-ELSO centres) identified and approached in 23 countries, 133 (63%) responded. Of these, 43% reported routine neuromonitoring during ECMO for all patients, 35% indicated selective use, and 22% practiced bedside clinical examination alone. The reported neuromonitoring modalities were NIRS (n = 88, 66.2%), electroencephalography (n = 52, 39.1%), transcranial Doppler (n = 38, 28.5%) and brain injury biomarkers (n = 33, 24.8%). Paediatric centres (67%) reported using cranial ultrasound, though the frequency of monitoring varied widely. Before hospital discharge following ECMO, 50 (37.6%) reported routine neurological assessment and 22 (16.5%) routinely performed neuroimaging with more paediatric centres offering neurological assessment (65%) as compared to adult centres (20%). Only 15 (11.2%) had a structured longitudinal follow-up pathway (defined followup at regular intervals), while 99 (74.4%) had no follow-up programme. The majority (n = 96, 72.2%) agreed that there should be a longitudinal structured follow-up for ECMO survivors. Conclusions: This survey demonstrated significant variability in the use of different neuromonitoring modalities during and after ECMO. The perceived importance of neuromonitoring and follow-up was noted to be very high with agreement for a longitudinal structured follow-up programme, particularly in paediatric patients. Scientific society endorsed guidelines and minimum standards should be developed to inform local protocols. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

22. Persistent Markers of Kidney Injury in Children Who Developed Acute Kidney Injury After Pediatric Cardiac Surgery: A Prospective Cohort Study

Author

Van den Eynde, Jef, primary, Salaets, Thomas, additional, Louw, Jacoba J., additional, Herman, Jean, additional, Breysem, Luc, additional, Vlasselaers, Dirk, additional, Desmet, Lars, additional, Meyns, Bart, additional, Budts, Werner, additional, Gewillig, Marc, additional, and Mekahli, Djalila, additional

Published
2022
Full Text
View/download PDF

23. CHILDREN WHO DEVELOPED ACUTE KIDNEY INJURY AFTER PEDIATRIC CARDIAC SURGERY HAVE PERSISTENT MARKERS OF RENAL INJURY AT MID- AND LONG-TERM FOLLOW-UP

Author

Eynde, Jef Van den, primary, Salaets, Thomas, additional, Louw, Jacoba J., additional, Herman, Jean, additional, Breysem, Luc, additional, Vlasselaers, Dirk, additional, Desmet, Lars, additional, Meyns, Bart, additional, Budts, Werner, additional, Gewillig, Marc H., additional, and Mekahli, Djalila, additional

Published
2022
Full Text
View/download PDF

27. Strategies to Prevent Acute Kidney Injury after Pediatric Cardiac Surgery

Author

Van den Eynde, Jef, primary, Cloet, Nicolas, additional, Van Lerberghe, Robin, additional, Sá, Michel Pompeu B.O., additional, Vlasselaers, Dirk, additional, Toelen, Jaan, additional, Verbakel, Jan Y., additional, Budts, Werner, additional, Gewillig, Marc, additional, Kutty, Shelby, additional, Pottel, Hans, additional, and Mekahli, Djalila, additional

Published
2021
Full Text
View/download PDF

29. International survey of neuromonitoring and neurodevelopmental outcome in children and adults supported on extracorporeal membrane oxygenation in Europe

Author

Cvetkovic, Mirjana, primary, Chiarini, Giovanni, additional, Belliato, Mirko, additional, Delnoij, Thijs, additional, Zanatta, Paolo, additional, Taccone, Fabio Silvio, additional, Miranda, Dinis dos Reis, additional, Davidson, Mark, additional, Matta, Nashwa, additional, Davis, Carl, additional, IJsselstijn, Hanneke, additional, Schmidt, Matthieu, additional, Broman, Lars Mikael, additional, Donker, Dirk W, additional, Vlasselaers, Dirk, additional, David, Piero, additional, Di Nardo, Matteo, additional, Muellenbach, Ralf M, additional, Mueller, Thomas, additional, Barrett, Nicholas A, additional, Lorusso, Roberto, additional, Belohlavek, Jan, additional, and Hoskote, Aparna, additional

Published
2021
Full Text
View/download PDF

32. sj-pdf-2-prf-10.1177_02676591211042563 – Supplemental material for International survey of neuromonitoring and neurodevelopmental outcome in children and adults supported on extracorporeal membrane oxygenation in Europe

Author

Cvetkovic, Mirjana, Chiarini, Giovanni, Belliato, Mirko, Delnoij, Thijs, Zanatta, Paolo, Taccone, Fabio Silvio, Miranda, Dinis dos Reis, Davidson, Mark, Matta, Nashwa, Davis, Carl, IJsselstijn, Hanneke, Schmidt, Matthieu, Broman, Lars Mikael, Donker, Dirk W, Vlasselaers, Dirk, David, Piero, Di Nardo, Matteo, Muellenbach, Ralf M, Mueller, Thomas, Barrett, Nicholas A, Lorusso, Roberto, Belohlavek, Jan, and Hoskote, Aparna

Subjects
FOS: Clinical medicine, Cardiology, 110323 Surgery
Abstract

Supplemental material, sj-pdf-2-prf-10.1177_02676591211042563 for International survey of neuromonitoring and neurodevelopmental outcome in children and adults supported on extracorporeal membrane oxygenation in Europe by Mirjana Cvetkovic, Giovanni Chiarini, Mirko Belliato, Thijs Delnoij, Paolo Zanatta, Fabio Silvio Taccone, Dinis dos Reis Miranda, Mark Davidson, Nashwa Matta, Carl Davis, Hanneke IJsselstijn, Matthieu Schmidt, Lars Mikael Broman, Dirk W Donker, Dirk Vlasselaers, Piero David, Matteo Di Nardo, Ralf M Muellenbach, Thomas Mueller, Nicholas A Barrett, Roberto Lorusso, Jan Belohlavek and Aparna Hoskote in Perfusion

Published
2021
Full Text
View/download PDF

33. sj-pdf-1-prf-10.1177_02676591211042563 – Supplemental material for International survey of neuromonitoring and neurodevelopmental outcome in children and adults supported on extracorporeal membrane oxygenation in Europe

Author

Cvetkovic, Mirjana, Chiarini, Giovanni, Belliato, Mirko, Delnoij, Thijs, Zanatta, Paolo, Taccone, Fabio Silvio, Miranda, Dinis dos Reis, Davidson, Mark, Matta, Nashwa, Davis, Carl, IJsselstijn, Hanneke, Schmidt, Matthieu, Broman, Lars Mikael, Donker, Dirk W, Vlasselaers, Dirk, David, Piero, Di Nardo, Matteo, Muellenbach, Ralf M, Mueller, Thomas, Barrett, Nicholas A, Lorusso, Roberto, Belohlavek, Jan, and Hoskote, Aparna

Subjects
FOS: Clinical medicine, Cardiology, 110323 Surgery
Abstract

Supplemental material, sj-pdf-1-prf-10.1177_02676591211042563 for International survey of neuromonitoring and neurodevelopmental outcome in children and adults supported on extracorporeal membrane oxygenation in Europe by Mirjana Cvetkovic, Giovanni Chiarini, Mirko Belliato, Thijs Delnoij, Paolo Zanatta, Fabio Silvio Taccone, Dinis dos Reis Miranda, Mark Davidson, Nashwa Matta, Carl Davis, Hanneke IJsselstijn, Matthieu Schmidt, Lars Mikael Broman, Dirk W Donker, Dirk Vlasselaers, Piero David, Matteo Di Nardo, Ralf M Muellenbach, Thomas Mueller, Nicholas A Barrett, Roberto Lorusso, Jan Belohlavek and Aparna Hoskote in Perfusion

Published
2021
Full Text
View/download PDF

34. Pharmacokinetics of antibiotics in pediatric intensive care:Fostering variability to attain precision medicine

Author

Gijsen, Matthias, Vlasselaers, Dirk, Spriet, Isabel, Allegaert, Karel, Gijsen, Matthias, Vlasselaers, Dirk, Spriet, Isabel, and Allegaert, Karel

Abstract

Children show important developmental and maturational changes, which may contribute greatly to pharmacokinetic (PK) variability observed in pediatric patients. These PK alterations are further enhanced by disease-related, non-maturational factors. Specific to the intensive care setting, such factors include critical illness, inflammatory status, augmented renal clearance (ARC), as well as therapeutic interventions (e.g., extracorporeal organ support systems or whole-body hypothermia [WBH]). This narrative review illustrates the relevance of both maturational and non-maturational changes in absorption, distribution, metabolism, and excretion (ADME) applied to antibiotics. It hereby provides a focused assessment of the available literature on the impact of critical illness—in general, and in specific subpopulations (ARC, extracorporeal organ support systems, WBH)—on PK and potential underexposure in children and neonates. Overall, literature discussing antibiotic PK alterations in pediatric intensive care is scarce. Most studies describe antibiotics commonly monitored in clinical practice such as vancomycin and aminoglycosides. Because of the large PK variability, therapeutic drug monitoring, further extended to other antibiotics, and integration of model-informed precision dosing in clinical practice are suggested to optimise antibiotic dose and exposure in each newborn, infant, or child during intensive care.

Published
2021

37. Postoperative Cerebral Oxygen Saturation in Children After Congenital Cardiac Surgery and Long-Term Total Intelligence Quotient: A Prospective Observational Study

Author

Carra, Giorgia, primary, Flechet, Marine, additional, Jacobs, An, additional, Verstraete, Sören, additional, Vlasselaers, Dirk, additional, Desmet, Lars, additional, Van Cleemput, Hanna, additional, Wouters, Pieter, additional, Vanhorebeek, Ilse, additional, Van den Berghe, Greet, additional, Güiza, Fabian, additional, and Meyfroidt, Geert, additional

Published
2021
Full Text
View/download PDF

38. Impact of Early Parenteral Nutrition To Complete Failing Enteral Nutrition in Adult Critically Ill Patients: A Randomized Controlled Trial

Author

Casaer, Michael P, primary, Mesotten, Dieter, additional, Hermans, Greet, additional, Wouters, Pieter J, additional, Schetz, Miet, additional, Meyfroidt, Geert, additional, Van Cromphaut, Sophie, additional, Ingels, Catherine, additional, Meersseman, Philippe, additional, Muller, Jan, additional, Vlasselaers, Dirk, additional, Debaveye, Yves, additional, Desmet, Lars, additional, Dubois, Jasperina, additional, Van Assche, Aime, additional, Wilmer, Alexander, additional, and Van den Berghe, Greet, additional

Published
2011
Full Text
View/download PDF

42. Intensive insulin therapy in critically ill patients

Author

Van den Berghe, Greet, Wouters, Pieter, Weekers, Frank, Verwaest, Charles, Bruyninckx, Frans, Schetz, Miet, Vlasselaers, Dirk, Ferdinande, Patrick, Lauwers, Peter, and Bouillon, Roger

Subjects
Critically ill -- Care and treatment, Insulin -- Health aspects
Abstract

Insulin therapy can lower mortality rates among critically ill patients even if they are not diabetic. In a study of 1,548 patients, insulin therapy not only lowered mortality rates but decreased the risk of kidney failure, bloodstream infection, and peripheral nerve disease and reduced the need for blood transfusions.

Published
2001

43. Early versus Late Parenteral Nutrition in Critically Ill Adults

Author

Casaer, Michael P., Mesotten, Dieter, Hermans, Greet, Wouters, Pieter J., Schetz, Miet, Meyfroidt, Geert, Van Cromphaut, Sophie, Ingels, Catherine, Meersseman, Philippe, Muller, Jan, Vlasselaers, Dirk, Debaveye, Yves, Desmet, Lars, Dubois, Jasperina, Van Assche, Aime, Vanderheyden, Simon, Wilmer, Alexander, and Van den Berghe, Greet

Published
2011
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results