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Randomly selected vitiligo patients were treated with local corticosteroid and local psoralen solution (10 patients), oral psoralen (54 patients), oral psoralen and oral corticosteroid (25 patients) and oral corticosteroid (15 patients) for a period of 6 months to 1 year. The patients were evaluated at 2-4 weeks interval by noting the percentage of pigmentation. Good to excellent results were obtained with a combination of oral psoralen and oral corticosteroid in 72 percent cases which was the best result in comparison to other regimens. Acrofacial type were relatively resistant to treatment.

Hundred children (upto 12 years of age) with vitiligo seen over a 1-year period were evaluated for their clinical pattern and therapeutic response to various modalities. Maximum number (29 percent) of patients were in the age group 6 to 9 years. Most of the patients (94 percent) had upto 5 percent skin involvement and the commonest (61 percent) clinical variant was vitiligo vulgaris followed by focal vitiligo (23 percent). None of the patients had any associated systemic diseases. Most satisfactory response was seen with PUVA-Sol and systemic corticosteroid combination. Overall good response with topical corticosteroids was seen in 44 (55 percent) patients. Lesions over the face showed best response. There was no correlation of response to treatment with age, sex, duration of disease and family history of vitiligo.

403 cases of vitiligo were studied with relation to age, sex, social status, geographic area of origin, occupation, educational status, food habits including alcohol intake, duration of vitiligo, family history of vitiligo, associated dermatological disorders, associated systemic diseases, size, shape, symmetry and distribution pattern of vitiligo lesions. Investigations revealed associated systemic diseases in 94 and dermatological disorders in 34 patients. Patients were treated with different drug regimens which included topical and systemic psoralens, topical and systemic steroids, combination of psoralens and steroids, systemic cyclophosphamide, systemic zinc therapy and placental extract application. Best results were achieved by combination of systemic psoralens, systemic and topical steroids. 332 patients were followed up out of which 217 recovered. Sites of repigmentation i.e. perifolicular, periphery or diffuse; and time interval of repigmentation with different regimens were also studied.