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224 results on '"Viterbo, R."'

2. Clinical performance of 99m sestamibi SPECT/CT imaging in differentiating oncocytic tumors from renal cell carcinoma in routine clinical practice

Author

Braun, A., primary, Schober, J., additional, Castro Bigalli, A., additional, Chen, M., additional, Ginsburg, K., additional, Magee, D., additional, Bukavina, L., additional, Chen, D.Y., additional, Correa, A., additional, Greenberg, R.E., additional, Smaldone, M.C., additional, Viterbo, R., additional, Yu, J., additional, Uzzo, R., additional, and Kutikov, A., additional

Published
2022
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4. Associations between cognitive impairment at onset and disability accrual in young people with multiple sclerosis

Author

Carotenuto A., Moccia M., Costabile T., Signoriello E., Paolicelli D., Simone M., Lus G., Brescia Morra V., Lanzillo R., Rosa L., Barbarulo A. M., Falco F., Viterbo R. G., Lauro F., Carotenuto, Antonio, Moccia, Marcello, Costabile, Teresa, Signoriello, Elisabetta, Paolicelli, Damiano, Simone, Marta, Lus, Giacomo, Brescia Morra, Vincenzo, Lanzillo, Roberta, Carotenuto, A., Moccia, M., Costabile, T., Signoriello, E., Paolicelli, D., Simone, M., Lus, G., Brescia Morra, V., Lanzillo, R., Rosa, L., Barbarulo, A. M., Falco, F., Viterbo, R. G., and Lauro, F.

Subjects
Adult, Male, medicine.medical_specialty, Multiple Sclerosis, 020205 medical informatics, Adolescent, Population, lcsh:Medicine, 02 engineering and technology, Predictive markers, Risk Assessment, Article, 03 medical and health sciences, Disability Evaluation, Young Adult, 0302 clinical medicine, Cognition, Visual memory, Recurrence, Internal medicine, 0202 electrical engineering, electronic engineering, information engineering, medicine, Humans, Cognitive Dysfunction, Longitudinal Studies, Young adult, Age of Onset, 10. No inequality, education, lcsh:Science, Child, Retrospective Studies, education.field_of_study, Multidisciplinary, Proportional hazards model, business.industry, Multiple sclerosis, lcsh:R, Retrospective cohort study, Cognitive neuroscience, medicine.disease, Disease Progression, lcsh:Q, Female, Age of onset, business, 030217 neurology & neurosurgery, Follow-Up Studies
Abstract

Differently from the adult multiple sclerosis (MS) population, the predictive value of cognitive impairment in early-onset MS is still unknown. We aim to evaluate whether cognitive performances at disease onset predict disease progression in young people with MS. This is a retrospective study on early onset (

Published
2019

6. Disability assessment in the Google Maps era: a pilot study

Author

Lavorgna, L., Laffaldano, P., Abbadessa, G., Lanzillo, R., Esposito, S., Ippolito, D., Sparaco, M., Cepparulo, S., Lus, G., Viterbo, R., Marinella CLERICO, Ragonese, P., Borriello, G., Signoriello, E., Trojano, M., Tedeschi, G., and Bonavita, S.

Published
2019

7. Robot-assisted Versus Open Radical Cystectomy in Patients Receiving Perioperative Chemotherapy for Muscle-invasive Bladder Cancer: The Oncologist's Perspective from a Multicentre Study

Author

Necchi, A. Pond, G.R. Smaldone, M.C. Pal, S.K. Chan, K. Wong, Y.-N. Viterbo, R. Sonpavde, G. Harshman, L.C. Crabb, S. Alva, A. Chowdhury, S. De Giorgi, U. Srinivas, S. Agarwal, N. Bamias, A. Baniel, J. Golshayan, A.-R. Ladoire, S. Sternberg, C.N. Cerbone, L. Yu, E.Y. Bellmunt, J. Vaishampayan, U. Niegisch, G. Hussain, S. Bowles, D.W. Morales-Barrera, R. Milowsky, M.I. Theodore, C. Berthold, D.R. Sridhar, S.S. Powles, T. Rosenberg, J.E. Galsky, M.D.

Abstract

In contemporary cohorts of patients who have received perioperative chemotherapy for muscle-invasive bladder cancer, no substantial differences were found between robot-assited radical cystectomy (RARC) and open radical cystectomy, and the number of lymph nodes removed was higher with RARC. © 2017 European Association of Urology Background: Little is known about the outcomes of robot-assisted radical cystectomy (RARC) compared to open radical cystectomy (ORC) combined with perioperative chemotherapy for muscle-invasive urothelial bladder cancer (UBC). Objective: To evaluate surgical and oncological outcomes for RARC and ORC in multimodal treatment. Design, setting, and participants: Data from 28 centres were collected for cystectomies performed between January 2000 and July 2013. Intervention: RARC or ORC combined with perioperative chemotherapy for UBC. Outcome measures and statistical analysis: Fisher's exact tests, χ 2 tests, and Wilcoxon rank-sum tests were used to compare the RARC and ORC groups. Logistic and Cox regression analyses were performed to evaluate potential prognostic factors. Results and limitations: A total of 688 patients (n = 603 ORC and n = 85 RARC) were analysed; 60.6% received neoadjuvant chemotherapy, and 45.1% adjuvant chemotherapy. No significant differences in baseline characteristics were found between the groups. The median time from surgery to adjuvant chemotherapy was 1.9 mo for both RARC and ORC groups. The median number of lymph nodes removed was 21 (interquartile range [IQR] 14–35) for RARC and 13 (IQR 8–21) for ORC (p < 0.001); the results were confirmed in subgroup analyses. Multivariable analyses revealed no difference in the rate of positive surgical margins (p = 0.54 and p = 0.78), rate of neobladder diversion (p = 0.33 and p = 0.51), relapse-free survival (p = 0.31 and p = 0.23), and overall survival (p = 0.63 and p = 0.69). The retrospective nature of the data is the major limitation. Conclusions: In this study, no differences in efficacy outcomes or ability to deliver adjuvant chemotherapy were observed between RARC and ORC. The increasing use of RARC is justifiable from an oncological viewpoint. Patient summary: In a retrospective study of patients who received perioperative chemotherapy for urothelial bladder cancer, we found no difference in key outcomes between robot-assisted radical cystectomy (RARC) and open radical cystectomy. Performing RARC seems to be justifiable in the multidisciplinary setting. © 2017 European Association of Urology

Published
2018

10. Cognitive and psychosocial features in childhood and juvenile Ms: two year follow up

Author

AMATO MP, GORETTI B, GHEZZI A, LORI S, ZIPOLI V, MOIOLA L, FALAUTANO M, DE CARRO MF, VITERBO R, PATTI F, VECCHIO R, POZZILLI C, BIANCHI V, ROSCIO M, MARTINELLI V, PORTACCIO E, TROJANO M., COMI , GIANCARLO, Amato, Mp, Goretti, B, Ghezzi, A, Lori, S, Zipoli, V, Moiola, L, Falautano, M, DE CARRO, Mf, Viterbo, R, Patti, F, Vecchio, R, Pozzilli, C, Bianchi, V, Roscio, M, Martinelli, V, Comi, Giancarlo, Portaccio, E, and Trojano, M.

Published
2010

11. Dosimetric and Clinical Predictors of Long-Term Toxicity in Patients Undergoing Hypofractionated Prostate Radiation Therapy: Results From a Randomized Phase 3 Trial

Author

Shaikh, T., primary, Ruth, K., additional, Devarajan, K., additional, Zaorsky, N.G., additional, Hallman, M.A., additional, Sobczak, M.L., additional, Chen, D., additional, Uzzo, R., additional, Smaldone, M.C., additional, Kutikov, A., additional, Greenberg, R.E., additional, Viterbo, R., additional, Pollack, A., additional, and Horwitz, E.M., additional

Published
2016
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14. Fatigue and its relationships with cognitive functioning and depression in paediatric multiple sclerosis

Author

Amato, Mp, Goretti, B, Portaccio, E, Zipoli, V, Centorrino, S, Contri, V, Razzolini, L, Giannini, M, Pastò, L, Lori, S, Falcini, M, Comi, G, Moiola, L, Martinelli, V, Falautano, M, Trojano, M, De Caro MF, Viterbo, R, Patti, F, Vecchio, R, Gallo, Paolo, Grossi, P, Bertolotto, A, Borghi, M, Pozzilli, C, Bianchi, V, Manca, I, Masia, C, Bergamaschi, R, Veggiotti, P, Ghezzi, A, Cappiello, S, and Roscio, M.

Published
2012

19. Cognitive and psychosocial features in childhood and juvenile MS Two-year follow-up

Author

Amato, Mp, Goretti, B, Zipoli, V, Portaccio, E, Centorrino, S, Contri, V, Lori, S, Falcini, M, Comi, G, Moiola, L, Falautano, M, Trojano, M, De Caro MF, Viterbo, R, Patti, F, Vecchio, R, Gallo, Paolo, Grossi, P, Bertolotto, A, Borghi, M, Pozzilli, C, Bianchi, V, Manca, I, Masia, C, Bergamaschi, R, Veggiotti, P, Ghezzi, A, and Roscio, M.

Published
2010

20. Psychosocial issue in children and adolescents with multiple sclerosis

Author

Amato, Mp, Goretti, B, Zipoli, V, Portaccio, E, Razzolini, L, Centorrino, S, Contri, V, Lori, S, Falcini, M, Comi, G, Moiola, L, Falautano, M, Trojano, M, De Caro MF, Viterbo, R, Patti, F, Vecchio, R, Gallo, Paolo, Grossi, P, Bertolotto, A, Borghi, M, Pozzilli, C, Bianchi, V, Manca, I, Masia, C, Bergamaschi, R, Veggiotti, P, Ghezzi, A, Trojano, Roscio M., and Amato, M. P.

Subjects
Male, medicine.medical_specialty, Activities of daily living, Adolescent, psychosocial features, Dermatology, Disease, children and adolescent, multiple sclerosis, Education, Cohort Studies, Interview, Psychological, medicine, Humans, Age of Onset, Psychiatry, Child, Depression (differential diagnoses), Fatigue, Psychiatric Status Rating Scales, Depression, Mental Disorders, General Medicine, Psychiatry and Mental health, Italy, Cohort, Disease Progression, Female, Neurology (clinical), Psychiatric interview, Age of onset, Psychology, Psychosocial, Clinical psychology, Cohort study
Abstract

In adult-onset multiple sclerosis (MS) cases, major depression, fatigue and psychological distress are common, whereas there is little information on these issues in children with the disease. The aim of this study was to assess psychosocial disorders in an Italian cohort of children and adolescent with MS. We evaluated 56 patients through self-assessment scales of depression (Children Depression Inventory) and fatigue (Fatigue Severity Scale), a psychiatric interview [Kiddie-SADS-Present and Lifetime Version (K-SADS-PL)] and an interview on school and everyday activities. Significant fatigue was found in 11 patients (20%). Twelve of the 39 patients who underwent the K-SADS-PL received a formal diagnosis of an affective disorder. Moreover, MS affected school activities in 28% of cases, daily living activities in 41% and social relationships in 28%. Our study confirms the critical role of psychosocial difficulties in children and adolescents with MS and provides a few cues to clinical management.

Published
2010

23. A Comparison of Urinary and Sexual Function Patient-Reported Outcomes (PROs) Among Treatment Modalities for Prostate Cancer (PCa)

Author

Johnson, M.E., primary, Martin, J.M., additional, Ruth, K.J., additional, Li, T., additional, Greenberg, R.E., additional, Uzzo, R.G., additional, Hayes, S.B., additional, Smaldone, M.C., additional, Kutikov, A., additional, Wong, Y.N., additional, Viterbo, R., additional, Chen, D.Y.T., additional, Sobczak, M.L., additional, and Horwitz, E.M., additional

Published
2014
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28. 522 NEOADJUVANT ACCELERATED MVAC IN PATIENTS WITH MUSCLE INVASIVE BLADDER CANCER: A MULTI-INSTITUTIONAL PROSPECTIVELY ACCRUED COHORT

Author

Mehrazin, Reza, primary, Plimack, E., additional, Kutikov, A., additional, Tomaszewski, J., additional, Hoffman-Censits, J., additional, Viterbo, R., additional, Greenberg, R., additional, Ginzburg, S., additional, Corcoran, A., additional, Lallas, C., additional, Trabulsi, E., additional, Wong, Y-N., additional, Boorjian, S., additional, Smaldone, M., additional, Uzzo, R., additional, and Chen, D., additional

Published
2013
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29. Load-dependent dysfunction of the putamen during attentional processing in patients with clinically isolated syndrome suggestive of multiple sclerosis

Author

Tortorella, C, primary, Romano, R, additional, Direnzo, V, additional, Taurisano, P, additional, Zoccolella, S, additional, Iaffaldano, P, additional, Fazio, L, additional, Viterbo, R, additional, Popolizio, T, additional, Blasi, G, additional, Bertolino, A, additional, and Trojano, M, additional

Published
2013
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37. Cognitive and psychosocial features in childhood and juvenile MS

Author

Amato, M.P., primary, Goretti, B., additional, Ghezzi, A., additional, Lori, S., additional, Zipoli, V., additional, Moiola, L., additional, Falautano, M., additional, De Caro, M.F., additional, Viterbo, R., additional, Patti, F., additional, Vecchio, R., additional, Pozzilli, C., additional, Bianchi, V., additional, Roscio, M., additional, Martinelli, V., additional, Comi, G., additional, Portaccio, E., additional, and Trojano, M., additional

Published
2010
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39. Fatigue and its relationships with cognitive functioning and depression in paediatric multiple sclerosis.

Author

Goretti, B, Portaccio, E, Ghezzi, A, Lori, S, Moiola, L, Falautano, M, Viterbo, R, Patti, F, Vecchio, R, Pozzilli, C, Bianchi, V, Cappiello, S, Comi, G, Trojano, M, and Amato, MP

Subjects
FATIGUE (Physiology), MULTIPLE sclerosis in children, COGNITIVE ability, DEPRESSION in children, PROBLEM solving in children
Abstract

Background: There is limited information on fatigue and its clinical and psychosocial correlates in children and adolescents with multiple sclerosis (MS).Objective: To assess the relationships between fatigue, cognitive functioning and depression in paediatric MS.Methods: The study cohort consisted of patients with MS recruited for an Italian collaborative study on cognitive and psychosocial functioning in paediatric MS. The present assessment included evaluation of fatigue on the Pediatric Quality of Life Inventory-Multidimensional Fatigue Scale, cognitive functioning on an extensive neuropsychological battery and depression on the Children’s Depression Inventory (CDI). A psychiatric interview through the Kiddie-SADS-Present and Lifetime Version was also administered.Results: In total, 57 patients with relapsing–remitting MS were compared with 70 healthy controls. Percentages of fatigued patients ranged from 9% to 14% according to self-reports, and from 23% to 39% according to parent reports. Fatigue was significantly related with higher scores on the CDI (p < 0.03). Higher levels of self-reported cognitive fatigue were associated with impaired performance on a problem-solving test, whereas higher levels of parent-reported cognitive fatigue were associated with impairment on tests of verbal learning, processing speed, complex attention and verbal comprehension.Conclusions: Our data show that fatigue can affect a sizeable proportion of paediatric MS patients, and confirm the association between fatigue and depressive symptoms in MS. They also highlight the difficulties of fatigue assessment in the paediatric population and provide a few clues to further research in the field. [ABSTRACT FROM AUTHOR]

Published
2012
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40. Small renal masses progressing to metastases under active surveillance: a systematic review and pooled analysis.

Author

Smaldone MC, Kutikov A, Egleston BL, Canter DJ, Viterbo R, Chen DY, Jewett MA, Greenberg RE, Uzzo RG, Smaldone, Marc C, Kutikov, Alexander, Egleston, Brian L, Canter, Daniel J, Viterbo, Rosalia, Chen, David Y T, Jewett, Michael A, Greenberg, Richard E, and Uzzo, Robert G

Abstract

Background: The authors systematically reviewed the literature and conducted a pooled analysis of studies on small renal masses who underwent active surveillance to identify the risk progression and the characteristics associated with metastases.Methods: A search of the MEDLINE database was performed to identify all clinical series that reported the surveillance of localized renal masses. For studies that reported individual-level data, clinical and radiographic characteristics of tumors without progression were compared with the characteristics of tumors that progressed to metastases.Results: Eighteen series (880 patients, 936 masses) met screening criteria; and, among these, 18 patients were identified who had tumors that progressed to metastasis (mean, 40.2 months). Six studies (259 patients, 284 masses) provided individual-level data for pooled analysis. At a mean (± standard deviation) follow-up of 33.5 ± 22.6 months, the mean initial greatest tumor dimension was 2.3 ± 1.3 cm, and mean linear growth rate was 0.31 ± 0.38 cm per year. Sixty-five masses (23%) exhibited zero net growth under surveillance, and none of those masses progressed to metastasis. A pooled analysis revealed increased age (age 75.1 ± 9.1 years vs 66.6 ± 12.3 years; P = .03), an initial greatest tumor dimension (4.1 ± 2.1 cm vs 2.3 ± 1.3 cm; P < .0001), initial estimated tumor volume (66.3 ± 100.0 cm(3) vs 15.1 ± 60.3 cm(3) ; p = .0001), linear growth rate of (0.8 ± 0.65 cm per year vs 0.3 ± 0.4 cm per year; P = .0001), and a volumetric growth rate of 27.1 ± 24.9 cm(3) per year (vs 6.2 ± 27.5 cm(3) per year; P < .0001) in the progression cohort.Conclusions: A substantial proportion of small renal masses remained radiographically static after an initial period of active surveillance. Progression to metastases occurred in a small percentage of patients and generally was a late event. The current results indicated that, in patients who have competing health risks, radiographic surveillance may be an acceptable initial approach, and delayed intervention may be reserved for patients who have tumors that exhibit significant linear or volumetric growth. [ABSTRACT FROM AUTHOR]

Published
2012
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