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4. A View from the past into our collective future: the oncofertility consortium vision statement.

Author

Woodruff, Teresa K, Ataman-Millhouse, Lauren, Acharya, Kelly S, Almeida-Santos, Teresa, Anazodo, Antoinette, Anderson, Richard A, Appiah, Leslie, Bader, Joy, Becktell, Kerri, Brannigan, Robert E, Breech, Lesley, Bourlon, Maria T, Bumbuliene, Žana, Burns, Karen, Campo-Engelstein, Lisa, Campos, Jacira R, Centola, Grace M, Chehin, Mauricio Barbour, Chen, Diane, De Vos, Michel, Duncan, Francesca E, El-Damen, Ahmed, Fair, Douglas, Famuyiwa, Yemi, Fechner, Patricia Y, Fontoura, Paula, Frias, Olivia, Gerkowicz, Sabrina A, Ginsberg, Jill, Gracia, Clarisa R, Goldman, Kara, Gomez-Lobo, Veronica, Hazelrigg, Brent, Hsieh, Michael H, Hoyos, Luis R, Hoyos-Martinez, Alfonso, Jach, Robert, Jassem, Jacek, Javed, Murid, Jayasinghe, Yasmin, Jeelani, Roohi, Jeruss, Jacqueline S, Kaul-Mahajan, Nalini, Keim-Malpass, Jessica, Ketterl, Tyler G, Khrouf, Mohamed, Kimelman, Dana, Kusuhara, Atsuko, Kutteh, William H, Laronda, Monica M, Lee, Jung Ryeol, Lehmann, Vicky, Letourneau, Joseph M, McGinnis, Lynda K, McMahon, Eileen, Meacham, Lillian R, Mijangos, Monserrat Fabiola Velez, Moravek, Molly, Nahata, Leena, Ogweno, George Moses, Orwig, Kyle E, Pavone, Mary Ellen, Peccatori, Fedro Alessandro, Pesce, Romina Ileana, Pulaski, Hanna, Quinn, Gwendolyn, Quintana, Ramiro, Quintana, Tomas, de Carvalho, Bruno Ramalho, Ramsey-Goldman, Rosalind, Reinecke, Joyce, Reis, Fernando M, Rios, Julie, Rhoton-Vlasak, Alice S, Rodriguez-Wallberg, Kenny A, Roeca, Cassandra, Rotz, Seth J, Rowell, Erin, Salama, Mahmoud, Saraf, Amanda J, Scarella, Anibal, Schafer-Kalkhoff, Tara, Schmidt, Deb, Senapati, Suneeta, Shah, Divya, Shikanov, Ariella, Shnorhavorian, Margarett, Skiles, Jodi L, Smith, James F, Smith, Kristin, Sobral, Fabio, Stimpert, Kyle, Su, H Irene, Sugimoto, Kouhei, Suzuki, Nao, Thakur, Mili, Victorson, David, Viale, Luz, Vitek, Wendy, and Wallace, W Hamish

Subjects
Fertility preservation, Oncofertility, cancer, Genetics, Paediatrics and Reproductive Medicine, Obstetrics & Reproductive Medicine
Abstract

PurposeToday, male and female adult and pediatric cancer patients, individuals transitioning between gender identities, and other individuals facing health extending but fertility limiting treatments can look forward to a fertile future. This is, in part, due to the work of members associated with the Oncofertility Consortium.MethodsThe Oncofertility Consortium is an international, interdisciplinary initiative originally designed to explore the urgent unmet need associated with the reproductive future of cancer survivors. As the strategies for fertility management were invented, developed or applied, the individuals for who the program offered hope, similarly expanded. As a community of practice, Consortium participants share information in an open and rapid manner to addresses the complex health care and quality-of-life issues of cancer, transgender and other patients. To ensure that the organization remains contemporary to the needs of the community, the field designed a fully inclusive mechanism for strategic planning and here present the findings of this process.ResultsThis interprofessional network of medical specialists, scientists, and scholars in the law, medical ethics, religious studies and other disciplines associated with human interventions, explore the relationships between health, disease, survivorship, treatment, gender and reproductive longevity.ConclusionThe goals are to continually integrate the best science in the service of the needs of patients and build a community of care that is ready for the challenges of the field in the future.

Published
2021

9. The National Physicians Cooperative: transforming fertility management in the cancer setting and beyond

Author

Smith, Brigid M, Duncan, Francesca E, Ataman, Lauren, Smith, Kristin, Quinn, Gwendolyn P, Chang, R Jeffrey, Finlayson, Courtney, Orwig, Kyle, Valli-Pulaski, Hanna, Moravek, Molly B, Zelinski, Mary B, Su, H Irene, Vitek, Wendy, Smith, James F, Jeruss, Jacqueline S, Gracia, Clarisa, Coutifaris, Christos, Shah, Divya, Nahata, Leena, Gomez-Lobo, Veronica, Appiah, Leslie Coker, Brannigan, Robert E, Gillis, Valerie, Gradishar, William, Javed, Asma, Rhoton-Vlasak, Alice S, Kondapalli, Laxmi A, Neuber, Evelyn, Ginsberg, Jill P, Muller, Charles H, Hirshfeld-Cytron, Jennifer, Kutteh, William H, Lindheim, Steven R, Cherven, Brooke, Meacham, Lillian R, Rao, Pooja, Torno, Lilibeth, Sender, Leonard S, Vadaparampil, Susan T, Skiles, Jodi L, Schafer-Kalkhoff, Tara, Frias, Oliva J, Byrne, Julia, Westphal, Lynn M, Schust, Danny J, Klosky, James L, McCracken, Kate A, Ting, Alison, Khan, Zaraq, Granberg, Candace, Lockart, Barbara, Scoccia, Bert, Laronda, Monica M, Mersereau, Jennifer E, Marsh, Courtney, Pavone, Mary Ellen, and Woodruff, Teresa K

Subjects
Reproductive Medicine, Biomedical and Clinical Sciences, Contraception/Reproduction, Cancer, Prevention, Reproductive health and childbirth, Good Health and Well Being, Adult, Antineoplastic Agents, Behavioral Medicine, Child, Disease Progression, Endocrinology, Female, Fertility, Fertility Preservation, Gynecology, Humans, Intersectoral Collaboration, Medical Oncology, Neoplasms, Obstetrics, Physicians, Practice Guidelines as Topic, Pregnancy, Quality of Life, United States, Urology, fertility preservation, oncofertility, reproductive health, Oncology and Carcinogenesis, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

Once unimaginable, fertility management is now a nationally established part of cancer care in institutions, from academic centers to community hospitals to private practices. Over the last two decades, advances in medicine and reproductive science have made it possible for men, women and children to be connected with an oncofertility specialist or offered fertility preservation soon after a cancer diagnosis. The Oncofertility Consortium's National Physicians Cooperative is a large-scale effort to engage physicians across disciplines - oncology, urology, obstetrics and gynecology, reproductive endocrinology, and behavioral health - in clinical and research activities to enable significant progress in providing fertility preservation options to children and adults. Here, we review the structure and function of the National Physicians Cooperative and identify next steps.

Published
2018

18. Association of uterine fibroids and pregnancy outcomes after ovarian stimulation–intrauterine insemination for unexplained infertility

Author

Styer, Aaron K., Jin, Susan, Liu, Dan, Wang, Baisong, Polotsky, Alex J., Christianson, Mindy S., Vitek, Wendy, Engmann, Lawrence, Hansen, Karl, Wild, Robert, Legro, Richard S., Coutifaris, Christos, Alvero, Ruben, Robinson, Randal D., Casson, Peter, Christman, Gregory M., Christy, Alicia, Diamond, Michael P., Eisenberg, Esther, Zhang, Heping, and Santoro, Nanette

Published
2017
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19. Comparison of sonohysterography to hysterosalpingogram for tubal patency assessment in a multicenter fertility treatment trial among women with polycystic ovary syndrome

Author

Christianson, Mindy S., Legro, Richard S., Jin, Susan, Eisenberg, Esther, Diamond, Michael P., Hansen, Karl R., Vitek, Wendy, Styer, Aaron K., Casson, Peter, Coutifaris, Christos, Christman, Gregory M., Alvero, Ruben, Puscheck, Elizabeth E., Christy, Alicia Y., Sun, Fangbai, Zhang, Heping, Polotsky, Alex J., and Santoro, Nanette

Published
2018
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42. When the personal becomes political: The impact of the Dobbs decision on women with cancer.

Author

Meisel, Jane Lowe, Harrington, Amy, Whaley, Natalie, Vitek, Wendy, and O'Regan, Ruth M.

Subjects
CANCER patients, LEGAL judgments, REPRODUCTIVE rights, PREGNANT women, CANCER prognosis
Abstract

Approximately 6400 pregnant women are diagnosed with cancer in the United States each year, and the recent decision by the Supreme Court to overturn the constitutional right to abortion will prevent many of these women from making critical decisions about their medical treatment. In many cases, lack of access to safe first‐trimester abortions may compromise these patients' cancer outcomes significantly, reducing their chances of living long enough to raise their child in the first place. [ABSTRACT FROM AUTHOR]

Published
2023
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43. Resolution of Hyperandrogenism, Insulin Resistance and Acanthosis Nigricans (HAIR-AN) Syndrome After Sleeve Gastrectomy.

Author

Lewin, Zoe, Vitek, Wendy S., O’Malley, William, and Astapova, Olga

Subjects
*HYPERANDROGENISM, *INSULIN resistance, *ACANTHOSIS nigricans, *SLEEVE gastrectomy, *TESTOSTERONE
Abstract

Hyperandrogenism, insulin resistance, and acanthosis nigricans (HAIR-AN) is a severe subphenotype of polycystic ovary syndrome (PCOS). A 32-year-old woman with HAIR-AN and class 3 obesity presented to an endocrinology clinic after she failed sequential trials of treatment with metformin, estrogen–progestin OCP, spironolactone, leuprolide, and a levonorgestrel intrauterine device. She complained of hirsutism and acanthosis nigricans severely affecting her quality of life and had secondary amenorrhea. Laboratory evaluation showed extremely elevated testosterone and insulin levels and elevated glycated hemoglobin A1c (HbA1c). She underwent laparoscopic sleeve gastrectomy. One year after the surgery, she lost 32% of her body weight and reported normalization of menses, dramatic improvement in hirsutism, and near-resolution of acanthosis nigricans. Her testosterone, insulin, and HbA1c normalized. This case demonstrates the central role of hyperinsulinemia in HAIR-AN and suggests that aggressive measures to normalize insulin resistance and reduce excess weight can effectively treat the reproductive abnormalities in this syndrome. We suggest that bariatric surgery can be an effective cure for HAIR-AN syndrome and that PCOS, including HAIR-AN, should be considered a comorbidity of obesity during evaluation of bariatric surgery candidates. [ABSTRACT FROM AUTHOR]

Published
2023
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