163 results on '"Vite, Gregory D."'
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2. Antibody–drug conjugates: current status and future directions
3. Synergistic inhibition of Aβ production by combinations of γ-secretase modulators
4. Pharmacology of smac mimetics; chemotype differentiation based on physical association with caspase regulators and cellular transport
5. Abstract 1140: A novel MTA non-competitive PRMT5 inhibitor
6. Design, synthesis and biological evaluation of phenol-linked uncialamycin antibody-drug conjugates
7. Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1
8. Pyrrolotriazine-5-carboxylate ester inhibitors of EGFR and HER2 protein tyrosine kinases and a novel one-pot synthesis of C-4 subsitituted pyrrole-2,3-dicarboxylate diesters (1)
9. Total Synthesis of Meayamycin and O-Acyl Analogues
10. Novel Androgen Receptor Antagonists for the Treatment of Prostate Cancer
11. Chapter 15 Case History: Discovery of Ixabepilone (IXEMPRATM), a First-in-Class Epothilone Analog for Treatment of Metastatic Breast Cancer
12. A novel application of a Pd(0)-catalyzed nucleophilic substitution reaction to the regio- and stereoselective synthesis of lactam analogues of the epothilone natural products
13. Highly Efficient Semisynthesis of Biologically Active Epothilone Derivatives
14. Identification of Novel Functional Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type III (17β-HSD3)
15. Development of a series of novel o-phenylenediamine-based indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors
16. Carbohydrates to carbocycles: synthesis of the densely functionalized carbocyclic core of tetrodotoxin by radical cyclization of an anhydro sugar precursor
17. Macrocyclic pyrrolobenzodiazepine dimers as antibody-drug conjugate payloads
18. Discovery of 4-Azaindole Inhibitors of TGFβRI as Immuno-oncology Agents
19. Identification and optimization of a novel series of indoleamine 2,3-dioxygenase inhibitors
20. [2.2.1]-Bicyclic sultams as potent androgen receptor antagonists
21. A facile method for the transformation of N-(tert-butoxycarbonyl) alpha-amino acids to N-unprotected alpha-amino methyl esters
22. Abstract 5789: Discovery of clinical candidate BMS-986158, an oral BET inhibitor, for the treatment of cancer
23. Abstract 5792: Preclinical antitumor activity of BMS-986158, an oral BET inhibitor, for the treatment of cancer
24. BMS-871: A novel orally active pan-Notch inhibitor as an anticancer agent
25. Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris
26. Discovery of the Selective CYP17A1 Lyase Inhibitor BMS-351 for the Treatment of Prostate Cancer
27. Abstract 5417: The identification of BMS-595, an orally active imidazo[1,2-b]pyridazine CK2 inhibitor with in vivo anti-tumor activity
28. Abstract 5395: Anti-tumor activity of BMS-595, a novel CK2 kinase inhibitor
29. Discovery of BMS-641988, a Novel Androgen Receptor Antagonist for the Treatment of Prostate Cancer
30. Dimeric Macrocyclic Antagonists of Inhibitor of Apoptosis Proteins for the Treatment of Cancer
31. Discovery of Clinical Candidate BMS-906024: A Potent Pan-Notch Inhibitor for the Treatment of Leukemia and Solid Tumors
32. Discovery of Potent Heterodimeric Antagonists of Inhibitor of Apoptosis Proteins (IAPs) with Sustained Antitumor Activity
33. Novel pyrrolo[2,1- f][1,2,4]triazin-4-amines: Dual inhibitors of EGFR and HER2 protein tyrosine kinases
34. Regioselective synthesis of folate receptor-targeted agents derived from epothilone analogs and folic acid
35. Identification and optimization of a novel series of [2.2.1]-oxabicyclo imide-based androgen receptor antagonists
36. ChemInform Abstract: AlMe3-Promoted Formation of Amides from Acids and Amines.
37. AlMe3-Promoted Formation of Amides from Acids and Amines
38. ChemInform Abstract: A Facile Method for the Transformation of N-(tert-Butoxycarbonyl) α-Amino Acids to N-Unprotected α-Amino Methyl Esters.
39. ChemInform Abstract: Synthesis and Biological Activity of Novel Epothilone Aziridines.
40. Discovery and Preclinical Evaluation of [4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamic Acid, (3S)-3-Morpholinylmethyl Ester (BMS-599626), a Selective and Orally Efficacious Inhibitor of Human Epidermal Growth Factor Receptor 1 and 2 Kinases
41. Discovery of anticancer agents of diverse natural origin
42. 5-((4-Aminopiperidin-1-yl)methyl)pyrrolotriazine dual inhibitors of EGFR and HER2 protein tyrosine kinases
43. Novel C-5 aminomethyl pyrrolotriazine dual inhibitors of EGFR and HER2 protein tyrosine kinases
44. New C-5 substituted pyrrolotriazine dual inhibitors of EGFR and HER2 protein tyrosine kinases
45. Discovery of Potent HeterodimericAntagonists of Inhibitorof Apoptosis Proteins (IAPs) with Sustained Antitumor Activity.
46. Preclinical Antitumor Activity of BMS-599626, a pan-HER Kinase Inhibitor That Inhibits HER1/HER2 Homodimer and Heterodimer Signaling
47. Constitutively active receptor tyrosine kinases as oncogenes in preclinical models for cancer therapeutics
48. Identification of a novel series of tetrahydrodibenzazocines as inhibitors of 17β-hydroxysteroid dehydrogenase type 3
49. New dual inhibitors of EGFR and HER2 protein tyrosine kinases
50. Silvestrol and Episilvestrol, Potential Anticancer Rocaglate Derivatives fromAglaia silvestris.
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