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2. Ocular Manifestations in Juvenile Behçet’s Disease: A Registry-Based Analysis from the AIDA Network

Author

Gaggiano, Carla, Tufan, Abdurrahman, Guerriero, Silvana, Ragab, Gaafar, Sota, Jurgen, Gentileschi, Stefano, Costi, Stefania, Almaghlouth, Ibrahim A., Hinojosa-Azaola, Andrea, Tharwat, Samar, Sfikakis, Petros P., Lopalco, Giuseppe, Piga, Matteo, Conti, Giovanni, Fragoulis, George, Mauro, Angela, Batu, Ezgi D., Ozen, Seza, Tarsia, Maria, La Torre, Francesco, Kawakami-Campos, Perla A., Vitale, Antonio, Caggiano, Valeria, Kardaş, Riza C., Tosi, Gian Marco, Frediani, Bruno, Avčin, Tadej, Hernández-Rodríguez, José, Cantarini, Luca, and Fabiani, Claudia

Published
2024
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3. Effectiveness and Safety of Biosimilars in Pediatric Non-infectious Uveitis: Real-Life Data from the International AIDA Network Uveitis Registry

Author

Tarsia, Maria, Vitale, Antonio, Gaggiano, Carla, Sota, Jurgen, Maselli, Anna, Bellantonio, Chiara, Guerriero, Silvana, Dammacco, Rosanna, La Torre, Francesco, Ragab, Gaafar, Hegazy, Mohamed Tharwat, Fonollosa, Alex, Paroli, Maria Pia, Del Giudice, Emanuela, Maggio, Maria Cristina, Cattalini, Marco, Fotis, Lampros, Conti, Giovanni, Mauro, Angela, Civino, Adele, Diomeda, Federico, de-la-Torre, Alejandra, Cifuentes-González, Carlos, Tharwat, Samar, Hernández-Rodríguez, José, Gómez-Caverzaschi, Verónica, Pelegrín, Laura, Babu, Kalpana, Gupta, Vishali, Minoia, Francesca, Ruscitti, Piero, Costi, Stefania, Breda, Luciana, La Bella, Saverio, Conforti, Alessandro, Mazzei, Maria Antonietta, Carreño, Ester, Amin, Rana Hussein, Grosso, Salvatore, Frediani, Bruno, Tosi, Gian Marco, Balistreri, Alberto, Cantarini, Luca, and Fabiani, Claudia

Published
2024
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4. Impact of Comprehensive Genome Profiling on the Management of Advanced Non–Small Cell Lung Cancer: Preliminary Results From the Lung Cancer Cohort of the FPG500 Program

Author

Vitale, Antonio, Mastrantoni, Luca, Russo, Jacopo, Giacomini, Flavia, Giannarelli, Diana, Duranti, Simona, Vita, Emanuele, Nero, Camilla, DʼArgento, Ettore, Pasciuto, Tina, Giaco[Combining Grave Accent], Luciano, Di Salvatore, Mariantonietta, Panfili, Arianna, Stefani, Alessio, Cancellieri, Alessandra, Lococo, Filippo, De Paolis, Elisa, Livi, Vanina, Daniele, Gennaro, Trisolini, Rocco, Minucci, Angelo, Margaritora, Stefano, Lorusso, Domenica, Normanno, Nicola, Scambia, Giovanni, Tortora, Giampaolo, and Bria, Emilio

Published
2024
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5. Correction: Clinical and laboratory features associated with macrophage activation syndrome in Still’s disease: data from the international AIDA Network Still’s Disease Registry

Author

Triggianese, Paola, Vitale, Antonio, Lopalco, Giuseppe, Mayrink Giardini, Henrique Ayres, Ciccia, Francesco, Al-Maghlouth, Ibrahim, Ruscitti, Piero, Sfikakis, Petros Paul, Iannone, Florenzo, de Brito Antonelli, Isabele Parente, Patrone, Martina, Asfina, Kazi Nur, Di Cola, Ilenia, Laskari, Katerina, Gaggiano, Carla, Tufan, Abdurrahman, Sfriso, Paolo, Dagna, Lorenzo, Giacomelli, Roberto, Hinojosa-Azaola, Andrea, Ragab, Gaafar, Fotis, Lampros, Direskeneli, Haner, Spedicato, Veronica, Dagostin, Marilia Ambiel, Iacono, Daniela, Ali, Hebatallah Hamed, Cipriani, Paola, Sota, Jurgen, Kardas, Riza Can, Bindoli, Sara, Campochiaro, Corrado, Navarini, Luca, Gentileschi, Stefano, Martín-Nares, Eduardo, Torres-Ruiz, Jiram, Saad, Moustafa Ali, Kourtesi, Katerina, Alibaz-Oner, Fatma, Sevik, Gizem, Iagnocco, Annamaria, Makowska, Joanna, Govoni, Marcello, Monti, Sara, Maggio, Maria Cristina, La Torre, Francesco, Del Giudice, Emanuela, Hernández-Rodríguez, José, Bartoloni, Elena, Emmi, Giacomo, Chimenti, Maria Sole, Maier, Armin, Simonini, Gabriele, Conti, Giovanni, Olivieri, Alma Nunzia, Tarsia, Maria, De Paulis, Amato, Lo Gullo, Alberto, Więsik-Szewczyk, Ewa, Viapiana, Ombretta, Ogunjimi, Benson, Tharwat, Samar, Erten, Sukran, Nuzzolese, Rossana, Karamanakos, Anastasios, Frassi, Micol, Conforti, Alessandro, Caggiano, Valeria, Marino, Achille, Sebastiani, Gian Domenico, Gidaro, Antonio, Tombetti, Enrico, Carubbi, Francesco, Rubegni, Giovanni, Cartocci, Alessandra, Balistreri, Alberto, Fabiani, Claudia, Frediani, Bruno, and Cantarini, Luca

Published
2024
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7. Clinical and laboratory features associated with macrophage activation syndrome in Still’s disease: data from the international AIDA Network Still’s Disease Registry

Author

Triggianese, Paola, Vitale, Antonio, Lopalco, Giuseppe, Mayrink Giardini, Henrique Ayres, Ciccia, Francesco, Al-Maghlouth, Ibrahim, Ruscitti, Piero, Sfikakis, Petros Paul, Iannone, Florenzo, de Brito Antonelli, Isabele Parente, Patrone, Martina, Asfina, Kazi Nur, Di Cola, Ilenia, Laskari, Katerina, Gaggiano, Carla, Tufan, Abdurrahman, Sfriso, Paolo, Dagna, Lorenzo, Giacomelli, Roberto, Hinojosa-Azaola, Andrea, Ragab, Gaafar, Fotis, Lampros, Direskeneli, Haner, Spedicato, Veronica, Dagostin, Marilia Ambiel, Iacono, Daniela, Ali, Hebatallah Hamed, Cipriani, Paola, Sota, Jurgen, Kardas, Riza Can, Bindoli, Sara, Campochiaro, Corrado, Navarini, Luca, Gentileschi, Stefano, Martín-Nares, Eduardo, Torres-Ruiz, Jiram, Saad, Moustafa Ali, Kourtesi, Katerina, Alibaz-Oner, Fatma, Sevik, Gizem, Iagnocco, Annamaria, Makowska, Joanna, Govoni, Marcello, Monti, Sara, Maggio, Maria Cristina, La Torre, Francesco, Del Giudice, Emanuela, Hernández-Rodríguez, José, Bartoloni, Elena, Emmi, Giacomo, Chimenti, Maria Sole, Maier, Armin, Simonini, Gabriele, Conti, Giovanni, Olivieri, Alma Nunzia, Tarsia, Maria, De Paulis, Amato, Lo Gullo, Alberto, Więsik-Szewczyk, Ewa, Viapiana, Ombretta, Ogunjimi, Benson, Tharwat, Samar, Erten, Sukran, Nuzzolese, Rossana, Karamanakos, Anastasios, Frassi, Micol, Conforti, Alessandro, Caggiano, Valeria, Marino, Achille, Sebastiani, Gian Domenico, Gidaro, Antonio, Tombetti, Enrico, Carubbi, Francesco, Rubegni, Giovanni, Cartocci, Alessandra, Balistreri, Alberto, Fabiani, Claudia, Frediani, Bruno, and Cantarini, Luca

Published
2023
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8. Unfolding dermatologic spectrum of Behçet’s disease in Italy: real-life data from the International AIDA Network Behçet’s disease Registry

Author

D’Onghia, Martina, Cinotti, Elisa, Cartocci, Alessandra, Vitale, Antonio, Caggiano, Valeria, Tognetti, Linda, La Marca, Francesca, Sota, Jurgen, Gentileschi, Stefano, Rubegni, Giovanni, Lopalco, Giuseppe, Guerriero, Silvana, Govoni, Marcello, Monti, Sara, Ruscitti, Piero, Angeli, Fabrizio, Carubbi, Francesco, Giacomelli, Roberto, Ciccia, Francesco, Piga, Matteo, Emmi, Giacomo, Costi, Stefania, Sebastiani, Gian Domenico, Iannone, Florenzo, Spedicato, Veronica, Alessio, Giovanni, Ruffilli, Francesca, Milanesi, Alessandra, Gentile, Martina, Crisafulli, Francesca, Alunno, Alessia, Navarini, Luca, Iacono, Daniela, Cauli, Alberto, Ricci, Francesca, Gaggiano, Carla, Tarsia, Maria, Bartoloni, Elena, Conti, Giovanni, Viapiana, Ombretta, Gobbi, Francesca Li, de Paulis, Amato, Parronchi, Paola, Del Giudice, Emanuela, Barone, Patrizia, Olivieri, Alma Nunzia, Bizzi, Emanuele, Maggio, Maria Cristina, Balistreri, Alberto, Frediani, Bruno, Tosi, Gian Marco, Fabiani, Claudia, Rubegni, Pietro, and Cantarini, Luca

Published
2023
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9. Event-driven Vision and Control for UAVs on a Neuromorphic Chip

Author

Vitale, Antonio, Renner, Alpha, Nauer, Celine, Scaramuzza, Davide, and Sandamirskaya, Yulia

Subjects
Electrical Engineering and Systems Science - Systems and Control, Computer Science - Artificial Intelligence
Abstract

Event-based vision sensors achieve up to three orders of magnitude better speed vs. power consumption trade off in high-speed control of UAVs compared to conventional image sensors. Event-based cameras produce a sparse stream of events that can be processed more efficiently and with a lower latency than images, enabling ultra-fast vision-driven control. Here, we explore how an event-based vision algorithm can be implemented as a spiking neuronal network on a neuromorphic chip and used in a drone controller. We show how seamless integration of event-based perception on chip leads to even faster control rates and lower latency. In addition, we demonstrate how online adaptation of the SNN controller can be realised using on-chip learning. Our spiking neuronal network on chip is the first example of a neuromorphic vision-based controller solving a high-speed UAV control task. The excellent scalability of processing in neuromorphic hardware opens the possibility to solve more challenging visual tasks in the future and integrate visual perception in fast control loops., Comment: Accepted for publication at the IEEE International Conference on Robotics and Automation (ICRA), Xi'an, 2021

Published
2021

10. Efficacy and Safety of Adalimumab in Pediatric Non-infectious Non-anterior Uveitis: Real-life Experience From the International AIDA Network Uveitis Registry

Author

Vitale, Antonio, Casa, Francesca Della, Guerriero, Silvana, Ragab, Gaafar, Mauro, Angela, Caggiano, Valeria, Cattalini, Marco, Del Giudice, Emanuela, Favale, Rossella, Gaggiano, Carla, Bellicini, Irene, Paroli, Maria Pia, Hegazy, Mohamed Tharwat, Sota, Jurgen, Tufan, Abdurrahman, Balistreri, Alberto, Almaghlouth, Ibrahim, La Torre, Francesco, Więsik-Szewczyk, Ewa, Tarsia, Maria, Hinojosa-Azaola, Andrea, Martín-Nares, Eduardo, Frediani, Bruno, Tosi, Gian Marco, Fonollosa, Alex, Hernández-Rodríguez, José, Amin, Rana Hussein, Lopalco, Giuseppe, Rigante, Donato, Cantarini, Luca, and Fabiani, Claudia

Published
2023
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11. Orbital/ocular inflammatory involvement in VEXAS syndrome: Data from the international AIDA network VEXAS registry

Author

Vitale, Antonio, Caggiano, Valeria, Martin-Nares, Eduardo, Frassi, Micol, Dagna, Lorenzo, Hissaria, Pravin, Sfriso, Paolo, Hernández-Rodríguez, José, Ruiz-Irastorza, Guillermo, Monti, Sara, Tufan, Abdurrahman, Piga, Matteo, Giardini, Henrique A Mayrink, Lopalco, Giuseppe, Viapiana, Ombretta, De Paulis, Amato, Triggianese, Paola, Vitetta, Rosetta, de-la-Torre, Alejandra, Fonollosa, Alex, Caroni, Federico, Sota, Jurgen, Conticini, Edoardo, Sbalchiero, Jessica, Renieri, Alessandra, Casamassima, Giulia, Wiesik-Szewczyk, Ewa, Yildirim, Derya, Hinojosa-Azaola, Andrea, Crisafulli, Francesca, Franceschini, Franco, Campochiaro, Corrado, Tomelleri, Alessandro, Callisto, Alicia, Beecher, Mark, Bindoli, Sara, Baggio, Chiara, Gómez-Caverzaschi, Verónica, Pelegrín, Laura, Soto-Peleteiro, Adriana, Milanesi, Alessandra, Vasi, Ibrahim, Cauli, Alberto, Antonelli, Isabele Parente de Brito, Iannone, Florenzo, Bixio, Riccardo, Casa, Francesca Della, Mormile, Ilaria, Gurnari, Carmelo, Fiorenza, Alessia, Mejia-Salgado, Germán, Kawakami-Campos, Perla Ayumi, Ragab, Gaafar, Ciccia, Francesco, Ruscitti, Piero, Bocchia, Monica, Balistreri, Alberto, Tosi, Gian Marco, Frediani, Bruno, Cantarini, Luca, and Fabiani, Claudia

Published
2024
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12. Enhanced Static and Dynamic Modeling of a Series-Series Inductive Power Transfer System with a Buck Post-Regulator

Author

Stoyka, Kateryna, Vitale, Antonio, Venere, Eugenio, Visconti, Paolo, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Pierfederici, Serge, editor, and Martin, Jean-Philippe, editor

Published
2023
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13. Design and Optimization of a Post-Regulated Inductive Power Transfer System with a Series-Series Compensation

Author

Vitale, Antonio, Stoyka, Kateryna, Venere, Eugenio, Visconti, Paolo, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Pierfederici, Serge, editor, and Martin, Jean-Philippe, editor

Published
2023
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14. Influence of gender on Behçet's disease phenotype and irreversible organ damage: Data from the International AIDA Network Behçet's Disease Registry

Author

Sota, Jurgen, Ragab, Gaafar, AlMaglouth, Ibrahim, Lopalco, Giuseppe, Tufan, Abdurrahman, Direskeneli, Haner, Hinojosa-Azaola, Andrea, Mayrink Giardini, Henrique Ayres, Guerriero, Silvana, Triaggianese, Paola, Sfikakis, Petros P., Piga, Matteo, Ruscitti, Piero, Govoni, Marcello, Iagnocco, Annamaria, Carubbi, Francesco, Hernández-Rodríguez, José, Laymouna, Ahmed Hatem, Mahmoud, Ayman Abdel-Monem Ahmed, Ghanema, Mahmoud, Aboabat, Aos A., Asfina, Kazi Nur, Alanazi, Fehaid, Morrone, Maria, Spedicato, Veronica, Kucuk, Hamit, Kardas, Riza, Alibaz Öner, Fatma, Sevik, Gizem, Torres-Ruiz, Jiram, Kawakami-Campos, Perla Ayumi, Parente de Brito Antonelli, Isabelle, Dammacco, Rosanna, Chimenti, Maria Sole, Arida, Katerina, Floris, Alberto, Gentile, Martina, Ruffilli, Francesca, Bellis, Elisa, Alunno, Alessia, Espinosa, Gerard, Gentileschi, Stefano, Gaggiano, Carla, Vitale, Antonio, Caggiano, Valeria, Lopez, Roberta, Tarsia, Maria, Monti, Sara, Hatemi, Gülen, Karakoç, Alican, Frassi, Micol, Giacomelli, Roberto, Tharwat, Samar, Thabet, Maissa, Ciccia, Francesco, Emmi, Giacomo, Viapiana, Ombretta, Şahin, Ali, Sebastiani, Gian Domenico, Batu, Ezgi Deniz, Ozen, Seza, Sener, Seher, Opris-Belinski, Daniela, Costi, Stefania, Conforti, Alessandro, Cattalini, Marco, Bartoloni, Elena, Akkoç, Nurullah, Gunduz, Ozgul Soysal, Conti, Giovanni, Maier, Armin, Giardina, Annarita, Li Gobbi, Francesca, Parronchi, Paola, Sarzi Puttini, Piercarlo, Breda, Luciana, De Paulis, Amato, Carreño, Ester, La Torre, Francesco, Więsik-Scewczyk, Ewa, de-la Torre, Alejandra, Mejía-Salgado, Germán, Shahram, Farhad, Guiducci, Serena, Maggio, Maria Cristina, Aragona, Emma, Rigante, Donato, Ciavarro, Alessandro, Önen, Fatos, Erten, Şükran, Insalaco, Antonella, Del Giudice, Emanuela, Barone, Patrizia, Gicchino, Francesca, Brucato, Antonio, Lo Gullo, Alberto, Mauro, Angela, Karamanakos, Anastasios, Balistreri, Alberto, Mazzei, Maria Antonietta, Frediani, Bruno, Fabiani, Claudia, and Cantarini, Luca

Published
2024
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15. Musculoskeletal manifestations in children with Behçet’s syndrome: data from the AIDA Network Behçet’s Syndrome Registry

Author

Gaggiano, Carla, Maselli, Anna, Sfikakis, Petros P., Laskari, Katerina, Ragab, Gaafar, Hegazy, Mohamed Tharwat, Laymouna, Ahmed Hatem, Lopalco, Giuseppe, Almaghlouth, Ibrahim A., Asfina, Kazi Nur, Alahmed, Ohoud, Giardini Mayrink, Henrique Ayres, Parente de Brito Antonelli, Isabele, Cattalini, Marco, Piga, Matteo, Sota, Jurgen, Gentileschi, Stefano, Maggio, Maria Cristina, Opris-Belinski, Daniela, Hatemi, Gülen, Insalaco, Antonella, Olivieri, Alma Nunzia, Tufan, Abdurrahman, Karadeniz, Hazan, Kardaş, Riza Can, La Torre, Francesco, Cardinale, Fabio, Marino, Achille, Guerriero, Silvana, Ruscitti, Piero, Tarsia, Maria, Vitale, Antonio, Caggiano, Valeria, Telesca, Salvatore, Iannone, Florenzo, Parretti, Veronica, Frassi, Micol, Aragona, Emma, Ciccia, Francesco, Wiesik-Szewczyk, Ewa, Ionescu, Ruxandra, Şahin, Ali, Akkoç, Nurullah, Hinojosa-Azaola, Andrea, Tharwat, Samar, Hernández-Rodríguez, José, Espinosa, Gerard, Conti, Giovanni, Del Giudice, Emanuela, Govoni, Marcello, Emmi, Giacomo, Fabiani, Claudia, Balistreri, Alberto, Frediani, Bruno, Rigante, Donato, and Cantarini, Luca

Published
2023
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18. Expert consensus on the treatment of patients with adult-onset still's disease with the goal of achieving an early and long-term remission

Author

Belfiore, Norma, Bernardi, Cristina, Gabini, Marco, Bettio, Silvano, Brucato, Antonio, Italiano, Giovanni, Cantatore, Francesco Paolo, Iacono, Daniela, Pantano, Ilenia, Tirri, Enrico, Ursini, Francesco, Monaco, Andrea Lo, Caso, Francesco, Quartuccio, Luca, Chimenti, Maria Sole, Gattamelata, Angelica, Gremese, Elisa, Paroli, Marino, Picchianti-Diamanti, Andrea, Sebastiani, Gian Domenico, Favalli, Ennio, Sulli, Alberto, Frassi, Micol, Faggioli, Paola, Foti, Rosario, Campochiaro, Corrado, Cavalli, Giulio, Tomelleri, Alessandro, Manara, Maria, De Stefano, Ludovico, De Angelis, Rossella, Parisi, Simone, Lopalco, Giuseppe, Piga, Matteo, Marotto, Daniela, Colaci, Michele, Padula, Angela, Guggino, Giuliana, Emmi, Giacomo, Baldini, Chiara, Sota, Jurgen, Vitale, Antonio, Berti, Alvise, Bartoloni, Elena, Grava, Chiara, Bindoli, Sara, Vitetta, Rosetta, Giacomelli, Roberto, Caporali, Roberto, Ciccia, Francesco, Colafrancesco, Serena, Dagna, Lorenzo, Govoni, Marcello, Iannone, Florenzo, Leccese, Pietro, Montecucco, Carlomaurizio, Pappagallo, Giovanni, Pistone, Giovanni, Priori, Roberta, Ruscitti, Piero, Sfriso, Paolo, and Cantarini, Luca

Published
2023
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19. The administration of methotrexate in patients with Still's disease, “real-life” findings from AIDA Network Still Disease Registry

Author

Ruscitti, Piero, Sota, Jurgen, Vitale, Antonio, Lopalco, Giuseppe, Iannone, Florenzo, Morrone, Maria, Giardini, Henrique Ayres Mayrink, D'Agostin, Marília Ambuel, Antonelli, Isabelle Parente de Brito, Almaghlouth, Ibrahim, Asfina, Kazi Nur, Khalil, Najma, Sfikakis, Petros P., Laskari, Katerina, Tektonidou, Maria, Ciccia, Francesco, Iacono, Daniela, Riccio, Flavia, Ragab, Gaafar, Hussein, Mohamed A., Govoni, Marcello, Ruffilli, Francesca, Direskeneli, Haner, Alibaz-Oner, Fatma, Giacomelli, Roberto, Navarini, Luca, Bartoloni, Elena, Riccucci, Ilenia, Martín-Nares, Eduardo, Torres-Ruiz, Jiram, Cipriani, Paola, Di Cola, Ilenia, Hernández-Rodríguez, José, Gómez-Caverzaschi, Verónica, Dagna, Lorenzo, Tomelleri, Alessandro, Makowska, Joanna, Brzezinska, Olga, Iagnocco, Annamaria, Bellis, Elisa, Caggiano, Valeria, Gaggiano, Carla, Tarsia, Maria, Mormile, Ilaria, Emmi, Giacomo, Sfriso, Paolo, Monti, Sara, Erten, Şükran, Del Giudice, Emanuela, Lubrano, Riccardo, Conti, Giovanni, Olivieri, Alma Nunzia, Lo Gullo, Alberto, Tharwat, Samar, Karamanakos, Anastasios, Gidaro, Antonio, Maggio, Maria Cristina, La Torre, Francesco, Cardinale, Fabio, Ogunjimi, Benson, Maier, Armin, Sebastiani, Gian Domenico, Opris-Belinski, Daniela, Frassi, Micol, Viapiana, Ombretta, Bizzi, Emanuele, Carubbi, Francesco, Fotis, Lampros, Tufan, Abdurrahman, Kardas, Riza Can, Więsik-Szewczyk, Ewa, Jahnz-Różyk, Karina, Fabiani, Claudia, Frediani, Bruno, Balistreri, Alberto, Rigante, Donato, and Cantarini, Luca

Published
2023
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21. Clinical characteristics of obese patients with adult-onset Still's disease. Data from a large multicentre cohort

Author

Di Cola, Ilenia, Iacono, Daniela, Pantano, Ilenia, Mauro, Daniele, Vitale, Antonio, Caso, Francesco, De Stefano, Ludovico, Prete, Marcella, Navarini, Luca, Ciaffi, Jacopo, Ursini, Francesco, Costa, Luisa, Perosa, Federico, Montecucco, Carlomaurizio, Cantarini, Luca, Frediani, Bruno, Ciccia, Francesco, Giacomelli, Roberto, Cipriani, Paola, and Ruscitti, Piero

Published
2023
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22. Ultrasound guided corticosteroids sacroiliac joint injections (SIJIs) in the management of active sacroiliitis: a real-life prospective experience

Author

Al Khayyat, Suhel G., Fogliame, Giuseppe, Barbagli, Stefano, Conticini, Edoardo, Fabbroni, Marta, D’Alessandro, Roberto, Vitale, Antonio, Gentileschi, Stefano, Bardelli, Marco, Baldi, Caterina, Stella, Salvatore Massimo, Saponara, Annarita, Del Chiaro, Andrea, Falsetti, Paolo, Cantarini, Luca, and Frediani, Bruno

Published
2022
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23. Development and implementation of the AIDA International Registry for patients with Behçet’s disease

Author

Vitale, Antonio, Della Casa, Francesca, Ragab, Gaafar, Almaghlouth, Ibrahim A., Lopalco, Giuseppe, Pereira, Rosa Maria, Guerriero, Silvana, Govoni, Marcello, Sfikakis, Petros P., Giacomelli, Roberto, Ciccia, Francesco, Monti, Sara, Ruscitti, Piero, Piga, Matteo, Lomater, Claudia, Tufan, Abdurrahman, Opris-Belinski, Daniela, Emmi, Giacomo, Hernández-Rodríguez, José, Şahin, Ali, Sebastiani, Gian Domenico, Bartoloni, Elena, Akkoç, Nurullah, Gündüz, Özgül Soysal, Cattalini, Marco, Conti, Giovanni, Hatemi, Gulen, Maier, Armin, Parronchi, Paola, Del Giudice, Emanuela, Erten, Sukran, Insalaco, Antonella, Li Gobbi, Francesca, Maggio, Maria Cristina, Shahram, Farhad, Caggiano, Valeria, Hegazy, Mohamed Tharwat, Asfina, Kazi Nur, Morrone, Maria, Prado, Leandro L., Dammacco, Rosanna, Ruffilli, Francesca, Arida, Aikaterini, Navarini, Luca, Pantano, Ilenia, Cavagna, Lorenzo, Conforti, Alessandro, Cauli, Alberto, Marucco, Elena Maria, Kucuk, Hamit, Ionescu, Ruxandra, Mattioli, Irene, Espinosa, Gerard, Araújo, Olga, Karkaş, Burak, Canofari, Claudia, Sota, Jurgen, Laymouna, Ahmed Hatem, Bedaiwi, Asma. A., Colella, Sergio, Giardini, Henrique Ayres M., Albano, Valeria, Lo Monaco, Andrea, Fragoulis, George E., Kardas, Riza Can, Berlengiero, Virginia, Hussein, Mohamed A., Ricci, Francesca, La Torre, Francesco, Rigante, Donato, Więsik-Szewczyk, Ewa, Frassi, Micol, Gentileschi, Stefano, Tosi, Gian Marco, Dagostin, Marilia Ambiel, Mahmoud, Ayman Abdel-Monem Ahmed, Tarsia, Maria, Alessio, Giovanni, Cimaz, Rolando, Giani, Teresa, Gaggiano, Carla, Iannone, Florenzo, Cipriani, Paola, Mourabi, Mariam, Spedicato, Veronica, Barneschi, Sara, Aragona, Emma, Balistreri, Alberto, Frediani, Bruno, Fabiani, Claudia, and Cantarini, Luca

Published
2022
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26. Efficacy and safety of tocilizumab in adult-onset Still's disease: Real-life experience from the international AIDA registry

Author

Sota, Jurgen, Vitale, Antonio, Lopalco, Giuseppe, Pereira, Rosa Maria R., Giordano, Heitor F., Antonelli, Isabele P.B., Makowska, Joanna, Brzezińska, Olga, Lewandowska-Polak, Anna, Ruscitti, Piero, Cipriani, Paola, Cola, Ilenia Di, Govoni, Marcello, Ruffili, Francesca, Sfikakis, Petros P., Laskari, Katerina, Ragab, Gaafar, Hussein, Mohamed A., Gentileschi, Stefano, Gaggiano, Carla, La Torre, Francesco, Maier, Armin, Emmi, Giacomo, Marino, Achille, Ciccia, Francesco, Sfriso, Paolo, Maggio, Maria Cristina, Bartoloni, Elena, Lomater, Claudia, Hegazy, Mohamed Tharwat, Tektonidou, Maria, Dagostin, Marília A., Opinc, Aleksandra, Sebastiani, Gian Domenico, Giacomelli, Roberto, Giudice, Emanuela Del, Olivieri, Alma Nunzia, Tufan, Abdurrahman, Kardas, Riza Kan, Nuzzolese, Rossana, Cardinale, Fabio, Więsik-Szewczyk, Ewa, Veronica, Parretti, Tarsia, Maria, Iannone, Florenzo, Della Casa, Francesca, Fabiani, Claudia, Frediani, Bruno, Balistreri, Alberto, Rigante, Donato, and Cantarini, Luca

Published
2022
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27. Development and Implementation of the AIDA International Registry for Patients with Non-Infectious Uveitis

Author

Casa, Francesca Della, Vitale, Antonio, Guerriero, Silvana, Sota, Jurgen, Cimaz, Rolando, Ragab, Gaafar, Ruscitti, Piero, Pereira, Rosa Maria R., Minoia, Francesca, Del Giudice, Emanuela, Emmi, Giacomo, Lomater, Claudia, Monti, Sara, Canofari, Claudia, Gaggiano, Carla, Alessio, Giovanni, Miserocchi, Elisabetta, Conforti, Alessandro, Dagostin, Marilia A., Mapelli, Chiara, Paroli, Maria Pia, Parretti, Veronica, Albano, Valeria, Favale, Rosa, Marelli, Luca, Hegazy, Mohamed Tharwat, Cipriani, Paola, Antonelli, Isabele P. B., Caggiano, Valeria, Aragona, Emma, Laymouna, Ahmed Hatem, Tosi, Gian Marco, Tarsia, Maria, Cattalini, Marco, La Torre, Francesco, Lopalco, Giuseppe, Więsik-Szewczyk, Ewa, Frassi, Micol, Gentileschi, Stefano, Giordano, Heitor F., Frediani, Bruno, Shinjo, Samuel K., Rigante, Donato, Sfikakis, Petros P., Balistreri, Alberto, Hussein, Mohamed A., Amin, Rana Hussein, Cantarini, Luca, and Fabiani, Claudia

Published
2022
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28. Development and Implementation of the AIDA International Registry for Patients with Non-Infectious Scleritis

Author

Della Casa, Francesca, Vitale, Antonio, Pereira, Rosa Maria, Guerriero, Silvana, Ragab, Gaafar, Lopalco, Giuseppe, Cattalini, Marco, Mattioli, Irene, Parronchi, Paola, Paroli, Maria Pia, Del Giudice, Emanuela, Gaggiano, Carla, Dagostin, Marília A., Albano, Valeria, Soliman, Mahmoud M., Colella, Sergio, Nascimbeni, Giuseppe, Sota, Jurgen, Antonelli, Isabele P. B., Alessio, Giovanni, Caggiano, Valeria, Tufan, Abdurrahman, Amin, Rana Hussein, Tarsia, Maria, Ghanema, Mahmoud, Iannone, Florenzo, Ricci, Francesca, La Torre, Francesco, Więsik-Szewczyk, Ewa, Conticini, Edoardo, Gentileschi, Stefano, Dammacco, Rosanna, Cimaz, Rolando, Frediani, Bruno, Abbruzzese, Anna, Ruscitti, Piero, Tosi, Gian Marco, Giordano, Heitor F., Conforti, Alessandro, Balistreri, Alberto, Rigante, Donato, Cantarini, Luca, and Fabiani, Claudia

Published
2022
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29. Secukinumab for the Treatment of Axial Spondyloarthritis: Long-Term Real-Life Data from Five Italian Referral Centers.

Author

Gentileschi, Stefano, Cannistrà, Carlo, Gaggiano, Carla, Damiani, Arianna, Carli, Linda, Benucci, Maurizio, Cantini, Fabrizio, Niccoli, Laura, Vitale, Antonio, Baldi, Caterina, Delle Sedie, Andrea, Cantarini, Luca, Mosca, Marta, Frediani, Bruno, and Guiducci, Serena

Subjects
BLOOD sedimentation, PSORIATIC arthritis, DRUG efficacy, C-reactive protein, SPONDYLOARTHROPATHIES
Abstract

Background: This study aimed to evaluate the effectiveness and drug retention rate of secukinumab (SCK) in axial spondyloarthritis (ax-SpA) within a multicentric real-life cohort. Methods: Data from patients with ax-SpA treated with SCK at five Italian centers were collected retrospectively, excluding those with a diagnosis of Psoriatic Arthritis. Evaluations were conducted at baseline and at 3, 6, 12, 18, and 24 months. Assessments included C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), BASDAI, and ASDAS-CRP. Results: Seventy-one ax-SpA patients (57.7% female, mean age: 53.86 ± 12.67 years) were enrolled. Baseline mean BASDAI was 6.2 ± 1.4 and ASDAS-CRP was 2.9 ± 1.3. Significant improvements in BASDAI and ASDAS-CRP were observed over time, with BASDAI reducing to 3.5 ± 1.9 (p < 0.0001) and ASDAS-CRP to 1.7 ± 0.9 (p < 0.0001) at 24 months. The follow-up duration averaged 20.46 ± 13.46 months. By the end of follow-up, 29.5% of patients discontinued SCK. The two-year retention rate was 72%. Dropout risk was higher in patients with fibromyalgia (HR: 2.896, p = 0.026). No significant retention differences were found based on sex, age, enthesitis, radiographic disease, combination with cDMARDs, SCK dosage, or previous bDMARD exposure. Lower ASDAS-CRP at the study's end was noted in patients without fibromyalgia (1.4 vs. 2.5, p < 0.001). Conclusions: SCK showed rapid and lasting effectiveness for ax-SpA with a favorable retention rate, though fibromyalgia may reduce treatment persistence. [ABSTRACT FROM AUTHOR]

Published
2024
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30. Dry eye disease and spondyloarthritis: expanding the spectrum of systemic inflammatory disorders associated with ocular surface disease. Data from the international AIDA Network Spondyloarthritis Registry.

Author

Vitale, Antonio, Caggiano, Valeria, Martín-Nares, Eduardo, Di Meglio, Nunzia, Sica, Cristian, Hinojosa-Azaola, Andrea, Perfetti, Maria Orsetta, Pagliara, Alessandra, Guidetti, Giorgia, Fonollosa, Alex, Lopez, Roberta, Sbalchiero, Jessica, Sota, Jurgen, Carre˜no, Ester, Kawakami-Campos, Perla Ayumi, Gentileschi, Stefano, de-la-Torre, Alejandra, Tosi, Gian Marco, Mazzei, Maria Antonietta, and Balistreri, Alberto

Published
2024
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33. Impact of smoking habit on adult-onset Still’s disease prognosis, findings from a multicentre observational study

Author

Ruscitti, Piero, Di Cola, Ilenia, Berardicurti, Onorina, Conforti, Alessandro, Iacono, Daniela, Pantano, Ilenia, Rozza, Gelsomina, Rossi, Silvia, De Stefano, Ludovico, Balduzzi, Silvia, Vitale, Antonio, Caso, Francesco, Costa, Luisa, Prete, Marcella, Navarini, Luca, Atzeni, Fabiola, Guggino, Giuliana, Perosa, Federico, Cantarini, Luca, Frediani, Bruno, Montecucco, Carlomaurizio, Ciccia, Francesco, Giacomelli, Roberto, and Cipriani, Paola

Published
2022
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34. Benefit of a multimodal approach combining chemotherapy and surgery in oligometastatic gastric cancer: experience from a tertiary referral center

Author

Maratta, Maria Grazia, primary, Vitale, Antonio, additional, Basso, Michele, additional, Vivolo, Raffaella, additional, Di Monte, Elena, additional, Biondi, Alberto, additional, Di Giorgio, Andrea, additional, Rosa, Fausto, additional, Tondolo, Vincenzo, additional, Agnes, Annamaria, additional, Tortora, Giampaolo, additional, Strippoli, Antonia, additional, and Pozzo, Carmelo, additional

Published
2024
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35. Risk for cancer development in familial Mediterranean fever and associated predisposing factors: an ambidirectional cohort study from the international AIDA Network registries

Author

Vitale, Antonio, primary, Caggiano, Valeria, additional, Tufan, Abdurrahman, additional, Ragab, Gaafar, additional, Batu, Ezgi Deniz, additional, Portincasa, Piero, additional, Aragona, Emma, additional, Sota, Jurgen, additional, Conti, Giovanni, additional, De Paulis, Amato, additional, Rigante, Donato, additional, Olivieri, Alma Nunzia, additional, Şahin, Ali, additional, La Torre, Francesco, additional, Lopalco, Giuseppe, additional, Cattalini, Marco, additional, Maggio, Maria Cristina, additional, Insalaco, Antonella, additional, Sfikakis, Petros P., additional, Verrecchia, Elena, additional, Yildirim, Derya, additional, Kucuk, Hamit, additional, Kardas, Riza Can, additional, Laymouna, Ahmed Hatem, additional, Ghanema, Mahmoud, additional, Saad, Moustafa Ali, additional, Sener, Seher, additional, Ercan Emreol, Hulya, additional, Ozen, Seza, additional, Jaber, Nour, additional, Khalil, Mohamad, additional, Di Ciaula, Agostino, additional, Gaggiano, Carla, additional, Malizia, Giuseppe, additional, Affronti, Andrea, additional, Patroniti, Serena, additional, Romeo, Meri, additional, Sbalchiero, Jessica, additional, Della Casa, Francesca, additional, Mormile, Ilaria, additional, Silvaroli, Sara, additional, Gicchino, Maria Francesca, additional, Çelik, Neşe Çabuk, additional, Tarsia, Maria, additional, Karamanakos, Anastasios, additional, Hernández-Rodríguez, José, additional, Parronchi, Paola, additional, Opris-Belinski, Daniela, additional, Barone, Patrizia, additional, Recke, Andreas, additional, Costi, Stefania, additional, Sfriso, Paolo, additional, Giardini, Henrique A. Mayrink, additional, Gentileschi, Stefano, additional, Wiesik-Szewczyk, Ewa, additional, Vasi, Ibrahim, additional, Loconte, Roberta, additional, Jahnz-Różyk, Karina, additional, Martín-Nares, Eduardo, additional, Torres-Ruiz, Jiram, additional, Cauli, Alberto, additional, Conforti, Alessandro, additional, Emmi, Giacomo, additional, Li Gobbi, Francesca, additional, Biasi, Giovanni Rosario, additional, Terribili, Riccardo, additional, Ruscitti, Piero, additional, Del Giudice, Emanuela, additional, Tharwat, Samar, additional, Brucato, Antonio Luca, additional, Ogunjimi, Benson, additional, Hinojosa-Azaola, Andrea, additional, Balistreri, Alberto, additional, Fabiani, Claudia, additional, Frediani, Bruno, additional, and Cantarini, Luca, additional

Published
2024
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37. Clinical profile and evolution of patients with juvenile-onset Behçet’s syndrome over a 25-year period: insights from the AIDA network

Author

Sota, Jurgen, Rigante, Donato, Lopalco, Giuseppe, Emmi, Giacomo, Gentileschi, Stefano, Gaggiano, Carla, Ciarcia, Luisa, Berlengiero, Virginia, Mourabi, Mariam, Ricco, Nicola, Barneschi, Sara, Mattioli, Irene, Tosi, Gian Marco, Frediani, Bruno, Tarsia, Maria, di Scala, Gerardo, Vitale, Antonio, Iannone, Florenzo, Fabiani, Claudia, and Cantarini, Luca

Published
2021
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40. Symptomatic androgen deficiency and sexual dysfunctions in male patients receiving alectinib for ALK-positive advanced nonsmall cell lung cancer

Author

Vita, Emanuele, Monaca, Federico, Milardi, Domenico, Mastrantoni, Luca, Stefani, Alessio, Vergani, Edoardo, Russo, Jacopo, Barone, Diletta, Sparagna, Ileana, Vitale, Antonio, Scala, Alessandro, Occhipinti, Deni, Di Salvatore, Mariantonietta, Pontecorvi, Alfredo, Tortora, Giampaolo, Bria, Emilio, Occhipinti, Denis, Pontecorvi, Alfredo (ORCID:0000-0003-0570-6865), Tortora, Giampaolo (ORCID:0000-0002-1378-4962), Bria, Emilio (ORCID:0000-0002-2333-704X), Vita, Emanuele, Monaca, Federico, Milardi, Domenico, Mastrantoni, Luca, Stefani, Alessio, Vergani, Edoardo, Russo, Jacopo, Barone, Diletta, Sparagna, Ileana, Vitale, Antonio, Scala, Alessandro, Occhipinti, Deni, Di Salvatore, Mariantonietta, Pontecorvi, Alfredo, Tortora, Giampaolo, Bria, Emilio, Occhipinti, Denis, Pontecorvi, Alfredo (ORCID:0000-0003-0570-6865), Tortora, Giampaolo (ORCID:0000-0002-1378-4962), and Bria, Emilio (ORCID:0000-0002-2333-704X)

Abstract

BackgroundIt is reported that treatment with anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) induces hypogonadism both in male patients with ALK-positive cancer and in murine models.MethodsIn this study, three groups, including an experimental group of male patients with ALK-positive, advanced nonsmall cell lung cancer (ANSCLC) who were receiving alectinib (cohort A), a control group of female patients with ALK-positive ANSCLC who were receiving alectinib (cohort B), and a control group of male patients with ALK-negative ANSCLC (cohort C), prospectively underwent a full hormone assessment for androgen deficiency at 8 weeks after the start of treatment and in case of reported suspected symptoms. Patients with major sexual dysfunctions were referred to an endocrinologist.ResultsNinety-five patients were consecutively enrolled onto the study. Among sixty-eight male patients, both median total testosterone levels (2.93 vs. 4.92 ng/ml; p = .0001) and free testosterone levels (0.11 vs. 0.17 pg/ml; p = .0002) were significantly lower in ALK-positive ANSCLC patients in cohort A compared with ALK-negative patients in cohort C; conversely, median FSH (10.32 vs. 17.52 mUI/ml; p = .0059) and LH levels (4.72 vs. 7.49 mUI/ml; p = .0131) were significantly higher in cohort C compared to cohort A. Median inhibin B levels were higher in ALK-positive male patients (74.3 vs. 44.24 pg/ml; p = .0038), but all patients had inhibin B values within the normal range. The percentage of male patients who had positive scores on the Androgen Deficiency in Aging Males (ADAM) questionnaire was 62% in cohort A and 26.8% in cohort C, including eight patients who reported at least one major symptom and were referred to Andrology Unit. No significant differences in the endocrine assessment were reported between cohorts A and B.ConclusionsSymptoms of androgen deficiency should be tracked in male patients with ALK-positive ANSCLC who are receiving alectinib, and testosterone replacem

Published
2024

41. Efficacy and safety of Janus kinase inhibitors in non-infectious inflammatory ocular diseases: a prospective cohort study from the international AIDA network registries.

Author

Vitale, Antonio, Palacios-Olid, Judith, Caggiano, Valeria, Ragab, Gaafar, Hernández-Rodríguez, José, Pelegrín, Laura, Mejía-Salgado, Germán, Zarate-Pinzón, Laura, Gentileschi, Stefano, Sota, Jurgen, Fonollosa, Alex, Carreño, Ester, Gaggiano, Carla, Amin, Rana Hussein, Balistreri, Alberto, Narváez, Javier, Tosi, Gian Marco, Frediani, Bruno, Cantarini, Luca, and de-la-Torre, Alejandra

Published
2024
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42. The Role of Biologic Agents in the Management of Pediatric-Onset Noninfectious Posterior Scleritis.

Author

Gaggiano, Carla, Berlengiero, Virginia, Vitale, Antonio, Tarsia, Maria, Grosso, Salvatore, Tosi, Gian Marco, Ricci, Francesca, Sota, Jurgen, Caggiano, Valeria, Frediani, Bruno, Cantarini, Luca, Cattalini, Marco, and Fabiani, Claudia

Subjects
BIOLOGICALS, PEDIATRIC ophthalmology, VISION, SCLERITIS, TREATMENT duration
Abstract

Registry-based observational prospective study aimed at describing the use of biologic drugs in pediatric-onset scleritis. Data were collected at baseline, at 3-, 6-, 12-month follow-up and at last assessment. Scleral inflammation was graded according to Sen classification. Five patients (9 eyes) treated with adalimumab, infliximab, abatacept and secukinumab were included. All patients were previously treated with conventional immunosuppressors and glucocorticoids. Median biologic treatment duration was 28 (IQR = 118) months. At 6-months, scleritis resolved in all eyes. At 12-months, complete disease control was observed in 7/9 eyes (77.8%). The number of relapses 12 months before and after treatment initiation was 17 and 2, respectively. Mean BCVA was 0.83 (range 0.3–1.0) at baseline and 1.0 for all eyes after 12 months. Glucocorticoids had been withdrawn in 4/5 patients. In conclusion, biological agents proved to be effective in pediatric-onset scleritis, allowing a noticeable steroid-sparing effect and preserving visual function and bulbar integrity. [ABSTRACT FROM AUTHOR]

Published
2024
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43. Symptomatic androgen deficiency and sexual dysfunctions in male patients receiving alectinib for ALK‐positive advanced non–small cell lung cancer.

Author

Vita, Emanuele, Monaca, Federico, Milardi, Domenico, Mastrantoni, Luca, Stefani, Alessio, Vergani, Edoardo, Russo, Jacopo, Barone, Diletta, Sparagna, Ileana, Vitale, Antonio, Scala, Alessandro, Occhipinti, Denis, Di Salvatore, Mariantonietta, Pontecorvi, Alfredo, Tortora, Giampaolo, and Bria, Emilio

Subjects
NON-small-cell lung carcinoma, ANAPLASTIC lymphoma kinase, SEXUAL dysfunction, PROTEIN-tyrosine kinase inhibitors, ANDROGENS, IMPOTENCE
Abstract

Background: It is reported that treatment with anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) induces hypogonadism both in male patients with ALK‐positive cancer and in murine models. Methods: In this study, three groups, including an experimental group of male patients with ALK‐positive, advanced non–small cell lung cancer (ANSCLC) who were receiving alectinib (cohort A), a control group of female patients with ALK‐positive ANSCLC who were receiving alectinib (cohort B), and a control group of male patients with ALK‐negative ANSCLC (cohort C), prospectively underwent a full hormone assessment for androgen deficiency at 8 weeks after the start of treatment and in case of reported suspected symptoms. Patients with major sexual dysfunctions were referred to an endocrinologist. Results: Ninety‐five patients were consecutively enrolled onto the study. Among sixty‐eight male patients, both median total testosterone levels (2.93 vs. 4.92 ng/ml; p =.0001) and free testosterone levels (0.11 vs. 0.17 pg/ml; p =.0002) were significantly lower in ALK‐positive ANSCLC patients in cohort A compared with ALK‐negative patients in cohort C; conversely, median FSH (10.32 vs. 17.52 mUI/ml; p =.0059) and LH levels (4.72 vs. 7.49 mUI/ml; p =.0131) were significantly higher in cohort C compared to cohort A. Median inhibin B levels were higher in ALK‐positive male patients (74.3 vs. 44.24 pg/ml; p =.0038), but all patients had inhibin B values within the normal range. The percentage of male patients who had positive scores on the Androgen Deficiency in Aging Males (ADAM) questionnaire was 62% in cohort A and 26.8% in cohort C, including eight patients who reported at least one major symptom and were referred to Andrology Unit. No significant differences in the endocrine assessment were reported between cohorts A and B. Conclusions: Symptoms of androgen deficiency should be tracked in male patients with ALK‐positive ANSCLC who are receiving alectinib, and testosterone replacement should be considered, as appropriate. Male patients with ALK‐positive advanced non–small cell lung cancer treated with first‐line alectinib had lower median total testosterone (p =.0001) and free testosterone (p =.0002) levels compared with male patients who had ALK‐negative disease and were receiving other anticancer treatments. Symptoms of hypogonadism were more frequent in ALK‐positive patients compared with ALK‐negative patients (62% vs 26.8% rates of positive score at ADAM questionnaire, respectively), suggesting the need for hormone assessment and referral to an andrologist, as appropriate. [ABSTRACT FROM AUTHOR]

Published
2024
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44. The Systemic Score May Identify Life‐Threatening Evolution in Still Disease: Data from the GIRRCS AOSD‐Study Group and the AIDA Network Still Disease Registry.

Author

Ruscitti, Piero, Masedu, Francesco, Vitale, Antonio, Caggiano, Valeria, Di Cola, Ilenia, Cipriani, Paola, Valenti, Marco, Mayrink Giardini, Henrique A, de Brito Antonelli, Isabele Parente, Dagostin, Marilia Ambiel, Lopalco, Giuseppe, Iannone, Florenzo, Maria, Morrone, Almaghlouth, Ibrahim A, Asfina, Kazi Nur, Ali, Hebatallah Hamed, Ciccia, Francesco, Iacono, Daniela, Pantano, Ilenia, and Mauro, Daniele

Subjects
RHEUMATOID arthritis diagnosis, RISK assessment, RHEUMATOID arthritis, SCIENTIFIC observation, SEVERITY of illness index, REPORTING of diseases, CHI-squared test, DESCRIPTIVE statistics, LONGITUDINAL method, ODDS ratio, LIVER diseases, RESEARCH, LUNG diseases, MACROPHAGE activation syndrome, CONFIDENCE intervals, DISEASE progression, DISEASE risk factors, DISEASE complications
Abstract

Objective: We aimed to evaluate the clinical usefulness of the systemic score in the prediction of life‐threatening evolution in Still disease. We also aimed to assess the clinical relevance of each component of the systemic score in predicting life‐threatening evolution and to derive patient subsets accordingly. Methods: A multicenter, observational, prospective study was designed including patients included in the Gruppo Italiano Di Ricerca in Reumatologia Clinica e Sperimentale Adult‐Onset Still Disease Study Group and the Autoinflammatory Disease Alliance Network Still Disease Registry. Patients were assessed to see if the variables to derive the systemic score were available. The life‐threatening evolution was defined as mortality, whatever the clinical course, and/or macrophage activation syndrome, a secondary hemophagocytic lymphohistiocytosis associated with a poor prognosis. Results: A total of 597 patients with Still disease were assessed (mean ± SD age 36.6 ± 17.3 years; male 44.4%). The systemic score, assessed as a continuous variable, significantly predicted the life‐threatening evolution (odds ratio [OR] 1.24; 95% confidence interval [CI] 1.07–1.42; P = 0.004). A systemic score ≥7 also significantly predicted the likelihood of a patient experiencing life‐threatening evolution (OR 3.36; 95% CI 1.81–6.25; P < 0.001). Assessing the clinical relevance of each component of the systemic score, liver involvement (OR 1.68; 95% CI 1.48–2.67; P = 0.031) and lung disease (OR 2.12; 95% CI 1.14–4.49; P = 0.042) both significantly predicted life‐threatening evolution. The clinical characteristics of patients with liver involvement and lung disease were derived, highlighting their relevance in multiorgan disease manifestations. Conclusion: The clinical utility of the systemic score was shown in identifying Still disease at a higher risk of life‐threatening evolution in a large cohort. Furthermore, the clinical relevance of liver involvement and lung disease was highlighted. [ABSTRACT FROM AUTHOR]

Published
2024
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45. Symptomatic androgen deficiency and sexual dysfunctions in male patients receiving alectinib for ALK‐positive advanced nonsmall cell lung cancer

Author

Vita, Emanuele, primary, Monaca, Federico, additional, Milardi, Domenico, additional, Mastrantoni, Luca, additional, Stefani, Alessio, additional, Vergani, Edoardo, additional, Russo, Jacopo, additional, Barone, Diletta, additional, Sparagna, Ileana, additional, Vitale, Antonio, additional, Scala, Alessandro, additional, Occhipinti, Denis, additional, Di Salvatore, Mariantonietta, additional, Pontecorvi, Alfredo, additional, Tortora, Giampaolo, additional, and Bria, Emilio, additional

Published
2024
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47. Correction to: Impact of smoking habit on adult-onset Still’s disease prognosis, findings from a multicentre observational study

Author

Ruscitti, Piero, Di Cola, Ilenia, Berardicurti, Onorina, Conforti, Alessandro, Iacono, Daniela, Pantano, Ilenia, Rozza, Gelsomina, Rossi, Silvia, De Stefano, Ludovico, Balduzzi, Silvia, Vitale, Antonio, Caso, Francesco, Costa, Luisa, Prete, Marcella, Navarini, Luca, Atzeni, Fabiola, Guggino, Giuliana, Perosa, Federico, Cantarini, Luca, Frediani, Bruno, Montecucco, Carlomaurizio, Ciccia, Francesco, Giacomelli, Roberto, and Cipriani, Paola

Published
2022
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49. Adalimumab effectively controls both anterior and posterior noninfectious uveitis associated with systemic inflammatory diseases: focus on Behçet’s syndrome

Author

Silvestri, Elena, Bitossi, Alice, Bettiol, Alessandra, Emmi, Giacomo, Urban, Maria Letizia, Mattioli, Irene, Di Scala, Gerardo, Bacherini, Daniela, Lopalco, Giuseppe, Venerito, Vincenzo, Iannone, Florenzo, Vitale, Antonio, Tosi, Gian Marco, Rizzo, Stanislao, Fabiani, Claudia, Cantarini, Luca, Virgili, Gianni, Vannozzi, Lorenzo, and Prisco, Domenico

Published
2020
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