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6,273 results on '"Viscusi, A."'

6. Integrating platelet reactivity in the age, creatinine and ejection fraction score to predict clinical outcomes following percutaneous coronary intervention in patients with chronic coronary syndrome: the PR-ACEF score

Author

Paolucci, Luca, Mangiacapra, Fabio, Viscusi, Michele Mattia, Sergio, Sara, Bressi, Edoardo, Colaiori, Iginio, Ricottini, Elisabetta, Cavallari, Ilaria, Nusca, Annunziata, Melfi, Rosetta, Ussia, Gian Paolo, and Grigioni, Francesco

Published
2024
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8. Catheter‐Based Renal Denervation for Resistant Arterial Hypertension: 10‐Year Real‐World Follow‐Up Data

Author

Sofie Brouwers, Giulia Botti, Matthias Verbesselt, Lucio Addeo, Marta Belmonte, Kostas Bermpeis, Dario Tino Bertolone, Chiara Valeriano, Michele Mattia Viscusi, and Eric Wyffels

Subjects
arterial hypertension, device‐based treatment, renal denervation, treatment, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

ABSTRACT This analysis of real‐world data examines the efficacy, safety, and long‐term outcomes of renal denervation in hypertensive patients for up to 10 years. Sixty‐five consecutive patients underwent renal denervation (RDN) (single operator) for uncontrolled resistant hypertension. Efficacy was defined as the interindividual change of office (OBPM) and ambulatory blood pressure monitoring (ABPM) at 1, 6, 12 months, 2–4 and 5–10 years after RDN. Medication changes, renal function, and device generation disparities were analyzed. Of these patients, 42 received RDN with a first‐generation device, while 23 underwent the procedure with a second‐generation device. Baseline demographics included a predominantly male cohort (57.6%) with an average age of 60.3 years. The mean number of medications at baseline was 4.3. OBPM at baseline was 169.0/87.4 mmHg, and ABPM at baseline was 153.4/88.4 mmHg. Post‐procedure, significant reductions in systolic blood pressure (SBP) were observed in both OBPM and ABPM at 1 month (OBPM 147.9/82.8 mmHg; ABPM 141.3/83.0 mmHg [SBP, p

Published
2024
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12. Pectin/alginate aerogel containing ZnO produced from beetroot extract mediated green synthesis for potential applications in food packaging

Author

Stefania Mottola, Gianluca Viscusi, Gianmaria Oliva, Giovanni Vigliotta, Stefano Cardea, Giuliana Gorrasi, and Iolanda De Marco

Subjects
Supercritical drying, Green synthesis, Functionalized aerogels, Antimicrobial activity, Technology
Abstract

In this work, pectin aerogels loaded with zinc oxide (ZnO) were produced for a possible application in food packaging. Using a green synthesis procedure, ZnO nanoparticles were obtained via beetroot extract as a reducing, capping, and stabilizing agent; the obtained ZnO particles, with an average size of 300 nm, were loaded into pectin/alginate-based aerogels. Supercritical drying was used to produce the biopolymers-based aerogels, which were initially formulated with different polymer concentrations (2 wt% and 4 wt%) and various ratios between pectin and alginate (9:1, 7:3, 1:1) to identify the optimal configuration that would guarantee a balance between strength and morphology, resulting in better properties in the final structure. The aerogels enriched with different ZnO percentages (5 %, 10 %, and 15 %) were later produced. The aerogels showed a porous structure with uniform pore size distribution, influenced by the ZnO loading. The liquids’ absorption test of the samples assessed that higher concentrations of ZnO could reduce the available surface area, limiting the aerogels’ absorption capacity. The potent antimicrobial activity of ZnO and pectin/alginate aerogels against the non-pathogenic Escherichia coli and the pathogenic Staphylococcus aureus strains was demonstrated using a minimum lethal dose, highlighting the possibility of employing such materials in food packaging.

Published
2025
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15. Design of Cellulose Acetate Electrospun Membranes Loaded with N-doped Carbon Quantum Dots for Water Remediation

Author

Viscusi, Gianluca, Mottola, Stefania, Tohamy, Hebat-Allah S., Gorrasi, Giuliana, De Marco, Iolanda, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Cui, Zhen-Dong, Series Editor, Lu, Xinzheng, Series Editor, Mannina, Giorgio, editor, and Ng, How Yong, editor

Published
2024
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33. Development of a protocol for fractionating and characterising fibres from lignocellulosic food waste

Author

Clara Pedrazzani, Pio Viscusi, Andrea Fuso, and Augusta Caligiani

Subjects
Dietary fibre, Food by-products, Fractionation, Soluble fibre, Insoluble fibre, Nutrition. Foods and food supply, TX341-641, Food processing and manufacture, TP368-456
Abstract

This study aims to explore an advanced protocol for characterising dietary fibre (DF) fractions to meet the growing demand for accurate and reliable data. Although current enzymatic-gravimetric approaches, e.g., AOAC and Van Soest analysis, provide information about soluble and insoluble DF quantification, they present limitations related to the lack of fractions characterisation. To overcome these limitations, the proposed protocol integrates the official AOAC 991.43 method with the sequential fibre fractionation by exploiting the different resistance of the fibre fractions to acid hydrolysis treatments (TFA and H2SO4), utilising hazelnut shells as a case-study. Each hydrolysed fraction was quantified and characterised through GC–MS analysis of monosaccharides. The data obtained for hemicellulose, cellulose, and lignin fractions were then discussed and compared with the Van Soest method. This approach yields a comprehensive procedure applicable to different food and nutraceutical products, emphasising the importance of DF characterisation for a deeper understanding of their bio-functional properties.

Published
2024
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34. Domains of Convergence for Polyhedral Packings

Author

Ahmed, Nooria, Ball, William, Buckminster, Ellis, Rivkin, Emilie, Torrance, Dylan, Viscusi, Jake, Wang, Runze, Whitehead, Ian, and Yang, S.

Subjects
Mathematics - Number Theory, Mathematics - Combinatorics, 52C26, 17B22 (Primary), 51F15, 17B67 (Secondary)
Abstract

Polyhedral circle packings are generalizations of the Apollonian packing. We develop the theory of the Apollonian group, Descartes quadratic form, and related objects for all polyhedral packings. We use these tools to determine the domain of absolute convergence of a generating function that can be associated to any polyhedral packing. This domain of convergence is the Tits cone for an infinite root system., Comment: 26 pages, 6 figures

Published
2021

37. Association between amount of biventricular pacing and heart failure status measured by a multisensor implantable defibrillator algorithm

Author

Santini, Luca, Calò, Leonardo, D’Onofrio, Antonio, Manzo, Michele, Dello Russo, Antonio, Savarese, Gianluca, Pecora, Domenico, Amellone, Claudia, Santobuono, Vincenzo Ezio, Calvanese, Raimondo, Viscusi, Miguel, Pisanò, Ennio, Pangallo, Antonio, Rapacciuolo, Antonio, Bertini, Matteo, Lavalle, Carlo, Santoro, Amato, Campari, Monica, Valsecchi, Sergio, and Boriani, Giuseppe

Published
2024
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40. Targeting the p90RSK/MDM2/p53 Pathway Is Effective in Blocking Tumors with Oncogenic Up-Regulation of the MAPK Pathway Such as Melanoma and Lung Cancer

Author

Immacolata Maietta, Eleonora Viscusi, Stefano Laudati, Giuseppe Iannaci, Antonio D’Antonio, Rosa Marina Melillo, Maria Letizia Motti, and Valentina De Falco

Subjects
p90RSK, p53, MDM2, apoptosis, tumorigenesis, cell proliferation, Cytology, QH573-671
Abstract

In most human tumors, the MAPK pathway is constitutively activated. Since p90RSK is downstream of MAPK, it is often hyperactive and capable of phosphorylating oncogenic substrates. We have previously shown that p90RSK phosphorylates MDM2 at S166, promoting p53 degradation in follicular thyroid carcinomas. Thus, the inhibition of p90RSK restores p53 expression, which in turn inhibits cell proliferation and promotes apoptosis. In the present study, we demonstrated that the p90RSK/MDM2/p53 pathway proved to be an excellent target in the therapy of tumors with MAPK hyperactivation. For this purpose, we selected p53wt melanoma, lung and medullary thyroid carcinoma cell lines with high activation of p90RSK. In these cell lines, we demonstrated that the p90RSK/MDM2/p53 pathway is implicated in the regulation of the cell cycle and apoptosis through p53-dependent transcriptional control of p21 and Bcl-2. Furthermore, with an immunohistochemical evaluation of primary melanomas and lung tumors, which exhibit highly activated p90RSK compared to corresponding normal tissue, we demonstrated that MDM2 stabilization was associated with p90RSK phosphorylation. The results indicate that p90RSK is able to control the proliferative rate and induction of apoptosis through the regulation of p53wt levels by stabilizing MDM2 in selected tumors with constitutively activated MAPKs, making p90RSK a new attractive target for anticancer therapy.

Published
2024
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41. Combined Cardiac Damage Staging by Echocardiography and Cardiac Catheterization in Patients With Clinically Significant Aortic Stenosis

Author

Belmonte, Marta, Paolisso, Pasquale, Bertolone, Dario Tino, Viscusi, Michele Mattia, Gallinoro, Emanuele, de Oliveira, Elayne Kelen, Shumkova, Monika, Beles, Monika, Esposito, Giuseppe, Addeo, Lucio, Botti, Giulia, Moya, Ana, Leone, Attilio, Wyffels, Eric, De Bruyne, Bernard, van Camp, Guy, Bartunek, Joseph, Barbato, Emanuele, Penicka, Martin, and Vanderheyden, Marc

Published
2024
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44. On groups with many normal subgroups

Author

Alessio Russo and Mario Viscusi

Subjects
normal subgroup, normal deviation, minimax group, Mathematics, QA1-939
Abstract

The structure of groups which are rich in normal subgroups has been investigated by several authors. Here, we prove that if a radical group G has normal deviation, which means that the set of its non-normal subgroups satisfies a very weak chain condition, then either G is a minimax group or all its subgroups are normal.

Published
2023
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47. On the Mechanical Behaviour of Carbon Fibre Laminates Repaired with Hot Bonding Technology by Infusion

Author

Donadio, Federica, Papa, Ilaria, Viscusi, Antonio, Carrino, Luigi, Lopresto, Valentina, Ingenito, Giancarlo, Caputo, Gabriella, Langella, Antonio, Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Haddar, Mohamed, Editorial Board Member, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Xu, Jinyang, Editorial Board Member, Lopresto, Valentina, editor, Papa, Ilaria, editor, and Langella, Antonio, editor

Published
2023
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48. USING OBJECTIVE CHARACTERISTICS TO TARGET HOUSEHOLD RECYCLING POLICIES

Author

Huber, Joel, Viscusi, W. Kip, and Bell, Jason

Subjects
Raw materials -- Waste management, Recycling (Waste, etc.), Environmental issues, Law
Abstract

Household recycling is valuable because it reduces demand for virgin raw materials and lessens the cost of making products containing paper, metal, glass, or plastic. Effective recycling programs limit the [...]

Published
2023

50. Differentiating sensor changes in a composite heart failure ICD monitoring index: clinical correlates and implications

Author

Compagnucci, Paolo, Santobuono, Vincenzo Ezio, D’Onofrio, Antonio, Vitulano, Gennaro, Calò, Leonardo, Bertini, Matteo, Santini, Luca, Savarese, Gianluca, Lavalle, Carlo, Viscusi, Miguel, Giammaria, Massimo, Pecora, Domenico, Calvanese, Raimondo, Santoro, Amato, Ziacchi, Matteo, Casella, Michela, Averina, Viktoria, Campari, Monica, Valsecchi, Sergio, Capucci, Alessandro, and Dello Russo, Antonio

Published
2024
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