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1. Engineering Three-Dimensional-Printed Bioactive Polylactic Acid Alginate Composite Scaffolds with Antibacterial and In Vivo Osteoinductive Capacity

Author

Claudio Iván Serra-Aguado, Mar Llorens-Gámez, Pablo Vercet-Llopis, Virginia Martínez-Chicote, Sanjukta Deb, and Ángel Serrano-Aroca

Subjects
Methicillin-Resistant Staphylococcus aureus, Alginates, Animals, Water, General Materials Science, Rabbits, United States
Abstract

Although fused deposition modeling (FDM) has made it possible to create reproducible three-dimensional poly(lactic acid) (PLA) scaffolds, their efficacy for tissue engineering applications is limited by their lack of osteoinductive properties and antibacterial functions. Building on the success of the FDM constructs capable of supporting bone regeneration, we report here on the development of PLA scaffolds infused with sodium alginate cross-linked with both calcium and zinc divalent cations. Zn

Published
2022
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