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1. Which components of the global alignment proportionality score have the greatest impact on outcomes in adult spinal deformity corrective surgery?

Author

Onafowokan, Oluwatobi O., Krol, Oscar, Lafage, Virginie, Lafage, Renaud, Smith, Justin S., Line, Breton, Vira, Shaleen, Daniels, Alan H., Diebo, Bassel, Schoenfeld, Andrew J., Gum, Jeffrey, Kebaish, Khaled, Than, Khoi, Kim, Han Jo, Hostin, Richard, Gupta, Munish, Eastlack, Robert, Burton, Douglas, Schwab, Frank J., Shaffrey, Christopher, Klineberg, Eric O., Bess, Shay, and Passias, Peter G.

Published
2024
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2. Identifying Subsets of Patients With Adult Spinal Deformity Who Maintained a Positive Response to Nonoperative Management.

Author

Passias, Peter, Ahmad, Waleed, Tretiakov, Peter, Krol, Oscar, Segreto, Frank, Lafage, Renaud, Lafage, Virginie, Soroceanu, Alex, Daniels, Alan, Gum, Jeffrey, Line, Breton, Schoenfeld, Andrew, Vira, Shaleen, Hart, Robert, Burton, Douglas, Smith, Justin, Shaffrey, Christopher, Schwab, Frank, Bess, Shay, and Ames, Christopher

Subjects
Humans, Adult, Aged, Treatment Outcome, Retrospective Studies, Frailty, Quality of Life, Pain
Abstract

BACKGROUND: Adult spinal deformity (ASD) represents a major cause of disability in the elderly population in the United States. Surgical intervention has been shown to reduce disability and pain in properly indicated patients. However, there is a small subset of patients in whom nonoperative treatment is also able to durably maintain or improve symptoms. OBJECTIVE: To examine the factors associated with successful nonoperative management in patients with ASD. METHODS: We retrospectively evaluated a cohort of 207 patients with nonoperative ASD, stratified into 3 groups: (1) success, (2) no change, and (3) failure. Success was defined as a gain in minimal clinically importance difference in both Oswestry Disability Index and Scoliosis Research Society-Pain. Logistic regression model and conditional inference decision trees established cutoffs for success according to baseline (BL) frailty and sagittal vertical axis. RESULTS: In our cohort, 44.9% of patients experienced successful nonoperative treatment, 22.7% exhibited no change, and 32.4% failed. Successful nonoperative patients at BL were significantly younger, had a lower body mass index, decreased Charlson Comorbidity Index, lower frailty scores, lower rates of hypertension, obesity, depression, and neurological dysfunction (all P < .05) and significantly higher rates of grade 0 deformity for all Schwab modifiers (all P < .05). Conditional inference decision tree analysis determined that patients with a BL ASD-frailty index ≤ 1.579 (odds ratio: 8.3 [4.0-17.5], P < .001) were significantly more likely to achieve nonoperative success. CONCLUSION: Success of nonoperative treatment was more frequent among younger patients and those with less severe deformity and frailty at BL, with BL frailty the most important determinant factor. The factors presented here may be useful in informing preoperative discussion and clinical decision-making regarding treatment strategies.

Published
2023

6. The Evolution of Enhanced Recovery After Surgery: Assessing the Clinical Benefits of Developments Within Enhanced Recovery After Surgery Protocols in Adult Cervical Deformity Surgery

Author

Passias, Peter G., Tretiakov, Peter S., Onafowokan, Oluwatobi O., Galetta, Matthew, Lorentz, Nathan, Mir, Jamshaid M., Das, Ankita, Dave, Pooja, Lafage, Renaud, Yee, Timothy, Diebo, Bassel, Vira, Shaleen, Jankowski, Pawel P., Hockley, Aaron, Daniels, Alan, Schoenfeld, Andrew J., Mummaneni, Praveen, Paulino, Carl B., and Lafage, Virginie

Published
2024
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7. The Impact of Lumbopelvic Realignment Versus Prevention Strategies at the Upper-instrumented Vertebra on the Rates of Junctional Failure Following Adult Spinal Deformity Surgery

Author

Passias, Peter G., Williamson, Tyler K., Joujon-Roche, Rachel, Krol, Oscar, Tretiakov, Peter, Imbo, Bailey, Schoenfeld, Andrew J., Owusu-Sarpong, Stephane, Lebovic, Jordan, Mir, Jamshaid, Dave, Pooja, McFarland, Kimberly, Vira, Shaleen, Diebo, Bassel G., Park, Paul, Chou, Dean, Smith, Justin S., Lafage, Renaud, and Lafage, Virginie

Published
2024
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8. Risk of spinal surgery among individuals who have been re-vascularized for coronary artery disease

Author

Passias, Peter G., Ahmad, Waleed, Kapadia, Bhaveen H., Krol, Oscar, Bell, Joshua, Kamalapathy, Pramod, Imbo, Bailey, Tretiakov, Peter, Williamson, Tyler, Onafowokan, Oluwatobi O., Das, Ankita, Joujon-Roche, Rachel, Moattari, Kevin, Passfall, Lara, Kummer, Nicholas, Vira, Shaleen, Lafage, Virginie, Diebo, Bassel, Schoenfeld, Andrew J., and Hassanzadeh, Hamid

Published
2024
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11. The Importance of Incorporating Proportional Alignment in Adult Cervical Deformity Corrections Relative to Regional and Global Alignment: Steps Toward Development of a Cervical-Specific Score

Author

Passias, Peter G., Williamson, Tyler K., Pierce, Katherine E., Schoenfeld, Andrew J., Krol, Oscar, Imbo, Bailey, Joujon-Roche, Rachel, Tretiakov, Peter, Ahmad, Salman, Bennett-Caso, Claudia, Mir, Jamshaid, Dave, Pooja, McFarland, Kimberly, Owusu-Sarpong, Stephane, Lebovic, Jordan A., Janjua, Muhammad Burhan, de la Garza-Ramos, Rafael, Vira, Shaleen, Diebo, Bassel, Koller, Heiko, Protopsaltis, Themistocles S., Lafage, Renaud, and Lafage, Virginie

Published
2024
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12. Factors Influencing Maintenance of Alignment and Functional Improvement Following Adult Spinal Deformity Surgery: A 3-Year Outcome Analysis

Author

Passias, Peter G., Passfall, Lara, Moattari, Kevin, Krol, Oscar, Kummer, Nicholas A., Tretiakov, Peter, Williamson, Tyler, Joujon-Roche, Rachel, Imbo, Bailey, Burhan Janjua, Muhammad, Jankowski, Pawel, Paulino, Carl, Schwab, Frank J., Owusu-Sarpong, Stephane, Singh, Vivek, Ahmad, Salman, Onafowokan, Tobi, Lebovic, Jordan, Tariq, Muhammad, Saleh, Hesham, Vira, Shaleen, Smith, Justin S., Diebo, Bassel, and Schoenfeld, Andrew J.

Published
2024
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16. The Benefit of Addressing Malalignment in Revision Surgery for Proximal Junctional Kyphosis Following ASD Surgery

Author

Passias, Peter G., Krol, Oscar, Williamson, Tyler K., Lafage, Virginie, Lafage, Renaud, Smith, Justin S., Line, Breton, Vira, Shaleen, Lipa, Shaina, Daniels, Alan, Diebo, Bassel, Schoenfeld, Andrew, Gum, Jeffrey, Kebaish, Khaled, Park, Paul, Mundis, Gregory, Hostin, Richard, Gupta, Munish C., Eastlack, Robert, Anand, Neel, Ames, Christopher, Hart, Robert, Burton, Douglas, Schwab, Frank J., Shaffrey, Christopher, Klineberg, Eric, and Bess, Shay

Published
2023
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17. Impact of Frailty on the Development of Proximal Junctional Failure: Does Frailty Supersede Achieving Optimal Realignment?

Author

Krol, Oscar, McFarland, Kimberly, Owusu-Sarpong, Stephane, Sagoo, Navraj, Williamson, Tyler, Joujon-Roche, Rachel, Tretiakov, Peter, Imbo, Bailey, Dave, Pooja, Mir, Jamshaid, Lebovic, Jordan, Onafowokan, Oluwatobi O., Schoenfeld, Andrew J., De la Garza Ramos, Rafael, Janjua, Muhammad Burhan, Sciubba, Daniel M., Diebo, Bassel G., Vira, Shaleen, Smith, Justin S., Lafage, Virginie, Lafage, Renaud, and Passias, Peter G.

Published
2023
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18. “Reverse roussouly”: cervicothoracic curvature ratios define characteristic shapes in adult cervical deformity

Author

Passias, Peter G., Pierce, Katherine E., Williamson, Tyler, Vira, Shaleen, Owusu-Sarpong, Stephane, Singh, Ravinderjit, Krol, Oscar, Passfall, Lara, Kummer, Nicholas, Imbo, Bailey, Joujon-Roche, Rachel, Tretiakov, Peter, Moattari, Kevin, Abola, Matthew V., Ahmad, Waleed, Naessig, Sara, Ahmad, Salman, Singh, Vivek, Diebo, Bassel, and Lafage, Virginie

Published
2022
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19. The Impact of Lumbopelvic Realignment versus Prevention Strategies at the Upper-Instrumented Vertebra on Rates of Junctional Failure following Adult Spinal Deformity Surgery

Author

Passias, Peter G., Williamson, Tyler K., Joujon-Roche, Rachel, Krol, Oscar, Tretiakov, Peter, Imbo, Bailey, Schoenfeld, Andrew J., Owusu-Sarpong, Stephane, Lebovic, Jordan, Mir, Jamshaid, Dave, Pooja, McFarland, Kimberly, Vira, Shaleen, Diebo, Bassel G., Park, Paul, Chou, Dean, Smith, Justin S., Lafage, Renaud, and Lafage, Virginie

Published
2023
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20. Factors Influencing Maintenance of Alignment and Functional Improvement Following Adult Spinal Deformity Surgery: A 3-Year Outcome Analysis

Author

Passias, Peter G., Passfall, Lara, Moattari, Kevin, Krol, Oscar, Kummer, Nicholas A., Tretiakov, Peter, Williamson, Tyler, Joujon-Roche, Rachel, Imbo, Bailey, Burhan Janjua, Muhammad, Jankowski, Pawel, Paulino, Carl, Schwab, Frank J., Owusu-Sarpong, Stephane, Singh, Vivek, Ahmad, Salman, Onafowokan, Tobi, Lebovic, Jordan, Tariq, Muhammad, Saleh, Hesham, Vira, Shaleen, Smith, Justin S., Diebo, Bassel, and Schoenfeld, Andrew J.

Published
2023
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21. Development of New-Onset Cervical Deformity in Nonoperative Adult Spinal Deformity Patients With 2-Year Follow-Up.

Author

Passias, Peter G, Jalai, Cyrus M, Worley, Nancy, Vira, Shaleen, Scheer, Justin K, Smith, Justin S, Ramachandran, Subaraman, Soroceanu, Alexandra, Horn, Samantha R, Poorman, Gregory W, Protopsaltis, Themistocles S, Klineberg, Eric O, Sciubba, Daniel M, Kim, Han Jo, Hamilton, D Kojo, Lafage, Renaud, Lafage, Virginie, Ames, Christopher P, and INTERNATIONAL SPINE STUDY GROUP (ISSG)

Subjects
INTERNATIONAL SPINE STUDY GROUP, adult spinal deformity, cervical deformity, new-onset cervical deformity, nonoperative, Clinical Research, Pediatric, Neurosciences
Abstract

PurposeEvaluate the presence of new-onset cervical deformity (CD) in nonoperative adult spinal deformity (ASD) patients with extended follow-up, with consideration for predictors, prevalence, and impact on patient-reported outcomes.MethodsRetrospective review of a prospective nonoperative ASD cohort. New onset CD patients at 1- (CD-1Y) and 2-year (CD-2Y) follow-up were defined as displaying baseline cervical alignment. Univariate analyses determined differences in radiographic parameters and outcome scores of CD and maintained-cervical-alignment patients. Multivariate binary logistic regression models determined new-onset CD predictors.ResultsA total of 143 patients were included (mean age 54 years, mean body mass index 25.6 kg/m2, 86% female). Cervical deformity rate was 38.5% at baseline. New-onset CD incidence at 1- and 2-year follow-up was 30.0% and 41.7%, respectively. Global sagittal profile comparison of CD-1Y/CD-2Y versus maintained cervical alignment cases revealed no differences (P > .05) at any interval. Baseline C2-C7 sagittal vertical axis (SVA) was associated with increased new-onset CD risk at 1 (odds ratio [OR] 1.14, P = .025) and 2 years (OR 1.04, P = .032); prior spine surgical history was associated with CD risk at 1-year follow-up (OR 6.75, P = .047); baseline C2 slope was associated with increased CD risk at 2-year follow-up (OR 1.12, P = .041). CD development did not significantly impact health-related quality of life (P > .05).ConclusionsCervical deformity can manifest in nonoperative ASD patients: 30.0% at 1-year follow-up, and 41.7% at 2-year follow-up. Progressive CD manifested independently of thoracolumbar profile changes. Increased baseline C2-C7 SVA, C2 slope, and prior surgical history increased new-onset CD odds at 1 and 2 years.

Published
2018

22. Long-term Morbidity in Patients After Surgical Correction of Adult Spinal Deformity: Results From a Cohort With Minimum 5-year Follow-up

Author

Imbo, Bailey, Williamson, Tyler, Joujon-Roche, Rachel, Krol, Oscar, Tretiakov, Peter, Ahmad, Salman, Bennett-Caso, Claudia, Schoenfeld, Andrew J., Dinizo, Michael, De La Garza-Ramos, Rafael, Janjua, M. Burhan, Vira, Shaleen, Ihejirika-Lomedico, Rivka, Raman, Tina, O’Connell, Brooke, Maglaras, Constance, Paulino, Carl, Diebo, Bassel, Lafage, Renaud, Lafage, Virginie, and Passias, Peter G.

Published
2023
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23. Percutaneous screw fixation versus open fusion for the treatment of traumatic thoracolumbar fractures: A retrospective case series of 185 Patients with a single-level spinal column injury

Author

Neeley, Om J., Kafka, Benjamin, Tecle, Najib El, Shi, Chen, El Ahmadieh, Tarek Y., Sagoo, Navraj S., Davies, Matthew, Johnson, Zachary, Caruso, James P., Hoeft, Jennifer, Stutzman, Sonja E., Vira, Shaleen, Hunt Batjer, H., Bagley, Carlos A., Whitworth, Louis, and Aoun, Salah G.

Published
2022
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24. Health-related quality of life measures in adult spinal deformity: can we replace the SRS-22 with PROMIS?

Author

Passias, Peter G., Pierce, Katherine E., Krol, Oscar, Williamson, Tyler, Naessig, Sara, Ahmad, Waleed, Passfall, Lara, Tretiakov, Peter, Imbo, Bailey, Joujon-Roche, Rachel, Lebovic, Jordan, Owusu-Sarpong, Stephane, Moattari, Kevin, Kummer, Nicholas A., Maglaras, Constance, O’Connell, Brooke K., Diebo, Bassel G., Vira, Shaleen, Lafage, Renaud, Lafage, Virginie, Buckland, Aaron J., and Protopsaltis, Themistocles

Published
2022
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27. Determining the utility of three-column osteotomies in revision surgery compared with primary surgeries in the thoracolumbar spine: a retrospective cohort study in the United States.

Author

Williamson, Tyler Kade, Onafowokan, Oluwatobi O, Das, Ankita, Mir, Jamshaid Mahmood, Krol, Oscar, Tretiakov, Peter, Joujon-Roche, Rachel, Imbo, Bailey, Ahmad, Salman, Owusu-Sarpong, Stephane, Lebovic, Jordan, Vira, Shaleen, Schoenfeld, Andrew J, Janjua, Muhammad Burhan, Diebo, Bassel, Lafage, Renaud, Lafage, Virginie, and Passias, Peter Gust

Subjects
SPINE abnormalities, BODY mass index, ODDS ratio, MULTIVARIATE analysis, KYPHOSIS
Abstract

Study Design: Retrospective cohort study. Purpose: To determine the incidence and success of three-column osteotomies (3COs) performed in primary and revision adult spine deformity (ASD) corrective surgeries. Overview of Literature: 3COs are often required to correct severe, rigid ASD presentations. However, controversy remains on the utility of 3COs, particularly in primary surgery. Methods: Patients ASD having 2-year data were included and divided into 3CO and non-3CO (remaining ASD cohort) groups. For the subanalysis, patients were stratified based on whether they were undergoing primary (P3CO) or revision (R3CO) surgery. Multivariate analysis controlling for age, Charlson comorbidity index, body mass index, baseline pelvic incidence–lumbar lordosis, and fused levels evaluated the complication rates and radiographic and patient-reported outcomes between the 3CO and non-3CO groups. Results: Of the 436 patients included, 20% had 3COs. 3COs were performed in 16% of P3COs and 51% of R3COs. Both 3CO groups had greater severity in deformity and disability at baseline; however, only R3COs improved more than non-3COs. Despite greater segmental correction, 3COs had much lower rates of aligning in the lumbar distribution index (LDI), higher mechanical complications, and more reoperations when performed below L3. When comparing P3COs and R3COs, baseline lumbopelvic and global alignments, as well as disability, were different. The R3CO group had greater clinical improvements and global correction (both p<0.04), although the P3CO group achieved alignment in LDI more often (odds ratio, 3.9; 95% confidence interval, 1.3–6.2; p=0.006). The P3CO group had more neurological complications (30% vs. 13%, p=0.042), whereas the R3CO tended to have higher mechanical complication rates (25% vs. 15%, p=0.2). Conclusions: 3COs showed greater improvements in realignment while failing to demonstrate the same clinical improvement as primaries without a 3CO. Overall, when suitably indicated, a 3CO offers superior utility for achieving optimal realignment across primary and revision surgeries for ASD correction. [ABSTRACT FROM AUTHOR]

Published
2024
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32. Crossing the Bridge from Degeneration to Deformity: When Does Sagittal Correction Impact Outcomes in Adult Spinal Deformity Surgery?

Author

Williamson, Tyler K, Krol, Oscar, Tretiakov, Peter, Joujon-Roche, Rachel, Imbo, Bailey, Ahmad, Salman, Owusu-Sarpong, Stephane, Lebovic, Jordan, Ihejirika-Lomedico, Rivka, Dinizo, Michael, Vira, Shaleen, Dhillon, Ekamjeet, O’Connell, Brooke, Maglaras, Constance, Schoenfeld, Andrew J, Janjua, M. Burhan, Alan, Nima, Diebo, Bassel, Paulino, Carl, Smith, Justin S., Raman, Tina, Lafage, Renaud, Protopsaltis, Themistocles, Lafage, Virginie, and Passias, Peter G.

Published
2022
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33. Advancements in Custom 3D-Printed Titanium Interbody Spinal Fusion Cages and Their Relevance in Personalized Spine Care.

Author

Lewandrowski, Kai-Uwe, Vira, Shaleen, Elfar, John C., and Lorio, Morgan P.

Subjects
*TECHNOLOGICAL innovations, *ARTIFICIAL implants, *SPINAL implants, *HEALTH facilities, *COST overruns, *LUMBAR vertebrae
Abstract

3D-printing technology has revolutionized spinal implant manufacturing, particularly in developing personalized and custom-fit titanium interbody fusion cages. These cages are pivotal in supporting inter-vertebral stability, promoting bone growth, and restoring spinal alignment. This article reviews the latest advancements in 3D-printed titanium interbody fusion cages, emphasizing their relevance in modern personalized surgical spine care protocols applied to common clinical scenarios. Furthermore, the authors review the various printing and post-printing processing technologies and discuss how engineering and design are deployed to tailor each type of implant to its patient-specific clinical application, highlighting how anatomical and biomechanical considerations impact their development and manufacturing processes to achieve optimum osteoinductive and osteoconductive properties. The article further examines the benefits of 3D printing, such as customizable geometry and porosity, that enhance osteointegration and mechanical compatibility, offering a leap forward in patient-specific solutions. The comparative analysis provided by the authors underscores the unique challenges and solutions in designing cervical, and lumbar spine implants, including load-bearing requirements and bioactivity with surrounding bony tissue to promote cell attachment. Additionally, the authors discuss the clinical outcomes associated with these implants, including the implications of improvements in surgical precision on patient outcomes. Lastly, they address strategies to overcome implementation challenges in healthcare facilities, which often resist new technology acquisitions due to perceived cost overruns and preconceived notions that hinder potential savings by providing customized surgical implants with the potential for lower complication and revision rates. This comprehensive review aims to provide insights into how modern 3D-printed titanium interbody fusion cages are made, explain quality standards, and how they may impact personalized surgical spine care. [ABSTRACT FROM AUTHOR]

Published
2024
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34. Comparison of multilevel low-grade techniques versus three-column osteotomies in adult spinal deformity surgery: does harmonious correction matter?

Author

Passias, Peter G., Williamson, Tyler K., Mir, Jamshaid M., Lebovic, Jordan A., Dave, Pooja, Tretiakov, Peter S., Joujon-Roche, Rachel, Imbo, Bailey, Krol, Oscar, Owusu-Sarpong, Stephane, Vira, Shaleen, Schoenfeld, Andrew J., Daniels, Alan H., Diebo, Bassel G., Lafage, Renaud, and Lafage, Virginie

Published
2024
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35. A cost utility analysis of treating different adult spinal deformity frailty states

Author

Brown, Avery E., Lebovic, Jordan, Alas, Haddy, Pierce, Katherine E., Bortz, Cole A., Ahmad, Waleed, Naessig, Sara, Hassanzadeh, Hamid, Labaran, Lawal A., Puvanesarajah, Varun, Vasquez-Montes, Dennis, Wang, Erik, Raman, Tina, Diebo, Bassel G., Vira, Shaleen, Protopsaltis, Themistocles S., Lafage, Virginie, Lafage, Renaud, Buckland, Aaron J., Gerling, Michael C., and Passias, Peter G.

Published
2020
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36. Hospital-acquired conditions occur more frequently in elective spine surgery than for other common elective surgical procedures

Author

Horn, Samantha R., Segreto, Frank A., Alas, Haddy, Bortz, Cole, Jackson-Fowl, Brendan, Brown, Avery E., Pierce, Katherine E., Vasquez-Montes, Dennis, Egers, Max I., Line, Breton G., Oh, Cheongeun, Moon, John, De la Garza Ramos, Rafael, Vira, Shaleen, Diebo, Bassel G., Frangella, Nicholas J., Stekas, Nicholas, Shepard, Nicholas A., Horowitz, Jason A., Hassanzadeh, Hamid, Bendo, John A., Lafage, Renaud, Lafage, Virginie, and Passias, Peter G.

Published
2020
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38. The Clinical Impact of Failing to Achieve Ideal Proportional Realignment in Adult Spinal Deformity Patients

Author

Passias, Peter G., Passfall, Lara, Williamson, Tyler K., Schoenfeld, Andrew J., Owusu-Sarpong, Stephane, Dhillon, Ekamjeet, Krol, Oscar, Kummer, Nicholas A., Tretiakov, Peter, Imbo, Bailey, Joujon-Roche, Rachel, Moattari, Kevin, Lebovic, Jordan, Vira, Shaleen, Diebo, Bassel, Smith, Justin S., Park, Paul, Mummaneni, Praveen, Shabani, Saman, Chou, Dean, Lafage, Renaud, and Lafage, Virginie

Published
2022
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39. Impact of congestive heart failure on patients undergoing lumbar spine fusion for adult spine deformity

Author

Onafowokan, Oluwatobi O., primary, Ahmad, Waleed, additional, McFarland, Kimberly, additional, Williamson, Tyler K., additional, Tretiakov, Peter, additional, Mir, Jamshaid M., additional, Das, Ankita, additional, Bell, Joshua, additional, Naessig, Sara, additional, Vira, Shaleen, additional, Lafage, Virginie, additional, Paulino, Carl, additional, Diebo, Bassel, additional, Schoenfeld, Andrew, additional, Hassanzadeh, Hamid, additional, Jankowski, Pawel P., additional, Hockley, Aaron, additional, and Passias, Peter Gust, additional

Published
2024
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42. Correction to: Prior bariatric surgery lowers complication rates following spine surgery in obese patients

Author

Passias, Peter G., Horn, Samantha R., Vasquez-Montes, Dennis, Shepard, Nicholas, Segreto, Frank A., Bortz, Cole A., Poorman, Gregory W., Jalai, Cyrus M., Wang, Charles, Stekas, Nicholas, Frangella, Nicholas J., Deflorimonte, Chloe, Diebo, Bassel G., Raad, Micheal, Vira, Shaleen, Horowitz, Jason A., Sciubba, Daniel M., Hassanzadeh, Hamid, Lafage, Renaud, Afthinos, John, and Lafage, Virginie

Published
2019
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43. Impact of presenting patient characteristics on surgical complications and morbidity in early onset scoliosis

Author

Segreto, Frank A., Vasquez-Montes, Dennis, Bortz, Cole A., Horn, Samantha R., Diebo, Bassel G., Vira, Shaleen, Kelly, John J., Stekas, Nicholas, Ge, David H., Ihejirika, Yael U., Lafage, Renaud, Lafage, Virginie, Karamitopoulos, Mara, Delsole, Edward M., Hockley, Aaron, Petrizzo, Anthony M., Buckland, Aaron J., Errico, Thomas J., Gerling, Michael C., and Passias, Peter G.

Published
2019
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44. Decreased rates of 30-day perioperative complications following ASD-corrective surgery: A modified Clavien analysis of 3300 patients from 2010 to 2014

Author

Passias, Peter G., Bortz, Cole A., Pierce, Katherine E., Segreto, Frank A., Horn, Samantha R., Vasquez-Montes, Dennis, Lafage, Virginie, Brown, Avery E., Ihejirika, Yael, Alas, Haddy, Varlotta, Christopher, Ge, David H., Shepard, Nicholas, Oh, Cheongeun, DelSole, Edward M., Jankowski, Pawel P., Hockley, Aaron, Diebo, Bassel G., Vira, Shaleen N., Sciubba, Daniel M., Raad, Michael, Neuman, Brian J., and Gerling, Michael C.

Published
2019
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45. Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013

Author

Passias, Peter G., Bortz, Cole, Alas, Haddy, Segreto, Frank A., Horn, Samantha R., Ihejirika, Yael U., Vasquez-Montes, Dennis, Pierce, Katherine E., Brown, Avery E., Shenoy, Kartik, DelSole, Edward M., Johnson, Bradley, Oh, Cheongeun, Zhou, Peter L., Deflorimonte, Chloe, Dhillon, Ekhamjeet S., Jankowski, Pawel P., Diebo, Bassel G., Lafage, Virginie, Lafage, Renaud, Vira, Shaleen N., Bendo, John A., Goldstein, Jeffrey A., Schwab, Frank J., and Gerling, Michael C.

Published
2019
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47. The Influence of Body Mass Index on Achieving Age-Adjusted Alignment Goals in Adult Spinal Deformity Corrective Surgery with Full-Body Analysis at 1 Year

Author

Horn, Samantha R., Segreto, Frank A., Ramchandran, Subbu, Poorman, Gregory R., Sure, Akhila, Marascalachi, Bryan, Bortz, Cole A., Varlotta, Christopher G., Tishelman, Jared, Vasquez-Montes, Dennis, Ihejirika, Yael, Zhou, Peter, Moon, John, Lafage, Renaud, Diebo, Bassel G., Vira, Shaleen, Jalai, Cyrus M., Wang, Charles, Shenoy, Kartik, Errico, Thomas, Lafage, Virginie, Buckland, Aaron, and Passias, Peter G.

Published
2018
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49. An Economic Analysis of Early and Late Complications After Adult Spinal Deformity Correction.

Author

Williamson, Tyler K., Owusu-Sarpong, Stephane, Imbo, Bailey, Krol, Oscar, Tretiakov, Peter, Joujon-Roche, Rachel, Ahmad, Salman, Bennett-Caso, Claudia, Schoenfeld, Andrew J., Lebovic, Jordan, Vira, Shaleen, Diebo, Bassel, Lafage, Renaud, Lafage, Virginie, and Passias, Peter G.

Subjects
SPINE abnormalities, ADULTS, SPINAL surgery, ECONOMIC impact, REOPERATION, MECHANICAL failures
Abstract

Study design/setting: Retrospective cohort. Objective: Adult spinal deformity (ASD) corrective surgery is often a highly invasive procedure portending patients to both immediate and long-term complications. Therefore, we sought to compare the economic impact of certain complications before and after 2 years. Methods: ASD patients with minimum 3-year data included. Complication groups were defined as follows: any complication, major, medical, mechanical, radiographic, and reoperation. Complications stratified by occurrence before or after 2 years postoperatively. Published methods converted ODI to SF-6D to QALYs. Cost was calculated using CMS.gov definitions. Marginalized means for utility gained and cost-per-QALY were calculated via ANCOVA controlling for significant confounders. Results: 244 patients included. Before 2Y, complication rates: 76% ≥1 complication, 18% major, 26% required reoperation. After 2Y, complication rates: 32% ≥1 complication, 4% major, 2.5% required reoperation. Major complications after 2 years had worse cost-utility (.320 vs.441, P =.1). Patients suffering mechanical complications accrued the highest overall cost ($130,482.22), followed by infection and PJF for complications before 2 years. Patients suffering a mechanical complication after 2 years had lower cost-utility ($109,197.71 vs $130,482.22, P =.041). Patients developing PJF after 2 years accrued a better cost-utility ($77,227.84 vs $96,873.57; P =.038), compared to PJF before 2 years. Conclusion: Mechanical complications had the single greatest impact on cost-utility after adult spinal deformity surgery, but less so after 2 years. Understanding the cost-utility of specific interventions at certain timepoints may mitigate economic burden and prophylactic efforts should strategically be made against early mechanical complications. [ABSTRACT FROM AUTHOR]

Published
2024
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50. Outcomes and survival analysis of adult cervical deformity patients with ten-year follow-up

Author

Passias, Peter G., primary, Tretiakov, Peter S., additional, Das, Ankita, additional, Thomas, Zach, additional, Krol, Oscar, additional, Joujon-Roche, Rachel, additional, Williamson, Tyler, additional, Imbo, Bailey, additional, Owusu-Sarpong, Stephane, additional, Lebovic, Jordan, additional, Diebo, Bassel, additional, Vira, Shaleen, additional, Lafage, Virginie, additional, and Schoenfeld, Andrew J., additional

Published
2023
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