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4. Données et preuves en vie réelle dans l’évaluation des technologies de santé : dans quels cas sont-elles complémentaires, substitutives, ou les seules sources de données par rapport aux essais cliniques ?

Author

de Pouvourville, Gérard, Armoiry, Xavier, Lavorel, Aurélie, Bilbault, Pascal, Maugendre, Philippe, Bensimon, Lionel, Beziz, Dan, Blin, Patrick, Borget, Isabelle, Bouée, Stéphane, Collignon, Cécile, Dervaux, Benoît, Durand-Zaleski, Isabelle, Julien, Marc, de Léotoing, Lucie, Majed, Laureen, Martelli, Nicolas, Séjourné, Thomas, and Viprey, Marie

Published
2023
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7. Determinants of adherence to post‐stroke/transient ischemic attack secondary prevention medications: A cohort study.

Author

Hoarau, Damien, Ramos, Inès, Termoz, Anne, Fernandez, Violaine, Rambure, Marie, Allemann, Samuel S., Derex, Laurent, Haesebaert, Julie, Schott, Anne‐Marie, and Viprey, Marie

Subjects
TRANSIENT ischemic attack, PATIENT compliance, SECONDARY prevention, STROKE, ANTIHYPERTENSIVE agents
Abstract

Background: Adherence to post‐stroke secondary prevention medications mitigates recurrence risk. This study aimed to measure adherence to secondary prevention medications during 3 years post‐ischemic stroke/transient ischemic attack, using prescription and dispensing data, and identify factors associated with suboptimal adherence. Methods: This multicenter, prospective, cohort study involved patients from the STROKE 69 cohort, which included all consecutive patients with suspected acute stroke admitted between November 2015 and December 2016 to any emergency department or stroke center in the Rhône area in France. Prescription data for antihypertensive agents, antidiabetic agents, lipid‐lowering drugs, and antithrombotics were collected. Dispensing data were provided by the French regional reimbursement database. Adherence was calculated using the continuous medication acquisition index. Associations between suboptimal adherence and potential influencing factors across the World Health Organization's five dimensions were explored through univariate and multivariate analyses. Results: From 1512 eligible patients, 365 were included. Optimal adherence to overall treatment (≥90%) was observed in 61%, 62%, and 65% of patients in the first, second, and third years, respectively. Education level (high school diploma or higher: OR = 3.24, 95% CI [1.49; 7.36]) and depression (Hospital Anxiety and Depression Scale–Depression scores 8–10: OR = 1.90, 95% CI [1.05; 3.44]) were significantly associated with suboptimal adherence. Conclusions: Overall adherence to secondary prevention medications was fairly good. Having an initial diagnosis of transient ischemic attack, a high level of education, or depression was associated with increased odds of suboptimal adherence, while having a history of heart rhythm disorder was associated with lower odds. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Real-world data and evidence in health technology assessment: When are they complementary, substitutes, or the only sources of data compared to clinical trials?

Author

de Pouvourville, Gérard, Armoiry, Xavier, Lavorel, Aurélie, Bilbault, Pascal, Maugendre, Philippe, Bensimon, Lionel, Beziz, Dan, Blin, Patrick, Borget, Isabelle, Bouée, Stéphane, Collignon, Cécile, Dervaux, Benoît, Durand-Zaleski, Isabelle, Julien, Marc, de Léotoing, Lucie, Majed, Laureen, Martelli, Nicolas, Séjourné, Thomas, and Viprey, Marie

Published
2022
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15. Interrater reliability in neurology objective structured clinical examination across specialties

Author

Mechtouff, Laura, primary, Balanca, Baptiste, additional, Jung, Julien, additional, Bourgeois-Vionnet, Julie, additional, Dumot, Chloé, additional, Guery, Déborah, additional, Picart, Thiébaud, additional, Bapteste, Lionel, additional, Demarquay, Geneviève, additional, Bani-Sadr, Alexandre, additional, Rascle, Lucie, additional, Berthezène, Yves, additional, Jacquesson, Timothée, additional, Amaz, Camille, additional, Macabrey, Juliette, additional, Ramos, Inès, additional, Viprey, Marie, additional, Rode, Gilles, additional, and Cortet, Marion, additional

Published
2023
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16. P1672: OCCUPATIONAL INTEGRATION OF ADULTS WITH SEVERE HAEMOPHILIA (INTHEMO): A STUDY BASED ON THE FRANCECOAG REGISTRY

Author

Nguyen, Ngoc Anh Thu, primary, Auquier, Pascal, additional, Anzola, Any Beltran, additional, D’oiron, Roseline, additional, Lambert, Thierry, additional, Falaise, Céline, additional, Biron, Christine, additional, Lienhart, Anne, additional, Goudemand, Jenny, additional, Rauch, Antoine, additional, Wibaut, Bénédicte, additional, Castet, Sabine Marie, additional, Desprez, Dominique, additional, Harroche, Annie, additional, Stieltjes, Natalie, additional, Borel-Derlon, Annie, additional, Trossaërt, Marc, additional, Celli, Amandine, additional, Guillet, Benoît, additional, Bayart, Sophie, additional, Bertrand, Marie-Anne, additional, Fournel, Alexandra, additional, Mourey, Guillaume, additional, Gay, Valérie, additional, Chamouni, Pierre, additional, Raucourt, Emmanuelle DE, additional, Frotscher, Birgit, additional, Martin, Michèle, additional, Puyade, Mathieu, additional, Tardy, Brigitte, additional, Vanderbecken, Stéphane, additional, Genre-Volot, Fabienne, additional, Nguyen, Philippe, additional, Polack, Benoît, additional, Oudot-Challard, Caroline, additional, Girault, Stéphane, additional, Voyer, Annelise, additional, Lebreton, Aurélien, additional, Hassoun, Abel, additional, Moreau, Philippe, additional, Rohrlich, Pierre-Simon, additional, Baumstarck, Karine, additional, Boucekine, Mohamed, additional, Milien, Vanessa, additional, Rosso, Natacha, additional, Tabele, Clemence, additional, Viprey, Marie, additional, Giraud, Nicolas, additional, Sannie, Thomas, additional, Chambost, Hervé, additional, and Resseguier, Noémie, additional

Published
2023
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20. Interrater reliability in neurology objective structured clinical examination across specialties.

Author

Mechtouff, Laura, Balanca, Baptiste, Jung, Julien, Bourgeois-Vionnet, Julie, Dumot, Chloé, Guery, Déborah, Picart, Thiébaud, Bapteste, Lionel, Demarquay, Geneviève, Bani-Sadr, Alexandre, Rascle, Lucie, Berthezène, Yves, Jacquesson, Timothée, Amaz, Camille, Macabrey, Juliette, Ramos, Inès, Viprey, Marie, Rode, Gilles, and Cortet, Marion

Subjects
OCCUPATIONAL roles, NEUROLOGY, CONFIDENCE intervals, MULTIVARIATE analysis, REGRESSION analysis, INTER-observer reliability, EDUCATIONAL tests & measurements, CLINICAL competence, INTRACLASS correlation, EDUCATORS, NEUROLOGIC examination, MEDICAL specialties & specialists, VIDEO recording, EVALUATION
Abstract

To assess interrater reliability and examiners' characteristics, especially specialty, associated with scoring of neurology objective structured clinical examination (OSCE). During a neurology mock OSCE, five randomly chosen students volunteers were filmed while performing 1 of the 5 stations. Video recordings were scored by physicians from the Lyon and Clermont-Ferrand university teaching hospitals to assess students performance using both a checklist scoring and a global rating scale. Interrater reliability between examiners were assessed using intraclass coefficient correlation. Multivariable linear regression models including video recording as random effect dependent variable were performed to detect factors associated with scoring. Thirty examiners including 15 (50%) neurologists participated. The intraclass correlation coefficient of checklist scores and global ratings between examiners were 0.71 (CI95% [0.45-0.95]) and 0.54 (CI95% [0.28-0.91]), respectively. In multivariable analyses, no factor was associated with checklist scores, while male gender of examiner was associated with lower global rating (β coefficient = –0.37; CI 95% [–0.62–0.11]). Our study demonstrated through a video-based scoring method that agreement among examiners was good using checklist scoring while moderate using global rating scale in neurology OSCE. Examiner's specialty did not affect scoring whereas gender was associated with global rating scale. [ABSTRACT FROM AUTHOR]

Published
2024
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23. A Participatory Approach Involving Patients with Cystic Fibrosis and Healthcare Professionals for the Co-Design of an Adherence-Enhancing Intervention Toolkit

Author

Viprey,Marie, Mougeot,Frédéric, Dima,Alexandra Lelia, Haesebaert,Julie, Occelli,Pauline, Durieu,Isabelle, Rouzé,Héloïse, Reynaud,Quitterie, Touzet,Sandrine, Viprey,Marie, Mougeot,Frédéric, Dima,Alexandra Lelia, Haesebaert,Julie, Occelli,Pauline, Durieu,Isabelle, Rouzé,Héloïse, Reynaud,Quitterie, and Touzet,Sandrine

Abstract

Marie Viprey,1,2 Frédéric Mougeot,3 Alexandra Lelia Dima,2,4 Julie Haesebaert,2,5 Pauline Occelli,2,5 Isabelle Durieu,2,6 Héloïse Rouzé,2,5 Quitterie Reynaud,2,6 Sandrine Touzet2,7 1Hospices Civils de Lyon, Pôle Santé Publique, Service des Données de Santé, Lyon, France; 2Research on Healthcare Performance RESHAPE, INSERM U1290, Université Claude Bernard Lyon 1, Lyon, France; 3Centre Max Weber, UMR 5283 - ENSEIS, Villeurbanne, France; 4Health Technology Assessment in Primary Care and Mental Health (PRISMA) Research Group, Parc Sanitari Sant Joan de Déu, Institut de Recerca Sant Joan de Déu, Barcelona, Spain; 5Hospices Civils de Lyon, Pôle Santé Publique, Service Recherche et Epidémiologie Cliniques, Lyon, France; 6Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Centre de Référence Adulte de la Mucoviscidose, Pierre Bénite, France; 7Hospices Civils de Lyon, Pôle Santé Publique, Service de Santé au Travail, Lyon, FranceCorrespondence: Marie Viprey, Hospices Civils de Lyon, Service des Données de Santé, 162 Avenue Lacassagne, Lyon, 69003, France, Tel +33 4 72 11 51 39, Fax +33 4 72 11 57 20, Email marie.viprey@chu-lyon.frPurpose: Cystic fibrosis (CF) is an inherited life-shortening disease involving a significant treatment burden. Few interventions have been proven effective in improving adherence, and of these fewer have been adopted for implementation. Patient participation in research is increasingly desired in developing relevant health care services. A participatory approach was implemented in an adult CF center to co-design an adherence-enhancing intervention toolkit. We aimed to report on the participatory process and the results regarding the co-designed intervention.Patients and Methods: Two focus group sessions and four working sessions were conducted at 4-week intervals with three healthcare professionals (HCP; physician, nurse, physiotherapist), eight patients, and two researchers (sociologist, public health pharmacist). The two

Published
2023

25. Determinants of adherence and consequences of the transition from adolescence to adulthood among young people with severe haemophilia (TRANSHEMO): A multicentric French national observational cross‐sectional study based on the FranceCoag registry.

Author

Nguyen, Ngoc Anh Thu, Auquier, Pascal, Beltran Anzola, Any, Harroche, Annie, Castet, Sabine, Huguenin, Yoann, Meunier, Sandrine, Repesse, Yohann, D'Oiron, Roseline, Rauch, Antoine, Desprez, Dominique, Spiegel, Alexandra, Chamouni, Pierre, Schneider, Pascale, Baumstarck, Karine, Boucekine, Mohamed, Tabele, Clémence, Viprey, Marie, Leroy, Tanguy, and Roques, Marie‐Anaïs

Subjects
YOUNG adults, TRANSITION to adulthood, ADOLESCENT health, TRANSITIONAL care, HEMOPHILIA, CROSS-sectional method
Abstract

Introduction: It is necessary to gain insights into adherence to healthcare in people with severe haemophilia (PwSH), especially during the transition from paediatric to adult care, which is an important phase in lives of young people with childhood chronic disease. This adherence can be considered as a marker of successful transition. Objectives: The main objective of the quantitative phase of the TRANSHEMO project was to compare the adherence to healthcare between adolescents and young adults (YAs) with severe haemophilia. The secondary objective was to identify the determinants (facilitators and barriers) of this adherence and associations between these determinants. Methods: A multicentre, observational, cross‐sectional study was conducted in 2017–2019 on PwSH aged between 14 and 17 years (adolescents) or between 20 and 29 years (YAs), included in the FranceCoag registry and having completed the questionnaires. The adherence to healthcare (treatment regimens and clinical follow‐up) was compared between adolescents and YAs using the chi‐squared test. The determinants of this adherence were analysed by structural equation modelling. Results: There were 277 participants, 107 adolescents, and 170 YAs. The rate of adolescents adhering to healthcare was 82.2%, while the rate of YAs was 61.2% (p <.001). The barriers to the adherence to healthcare were being YA, having repeated at least one school grade and presenting mental health concerns. Conclusion: Adolescents had better adherence to healthcare than YAs. According to the determinants enlightened in this project, targeted supportive strategies and adapted therapeutic education programs can be developed for young PwSH to facilitate their adherence to healthcare. [ABSTRACT FROM AUTHOR]

Published
2023
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27. Real-world data and evidence in health technology assessment: When are they complementary, substitutes, or the only sources of data compared to clinical trials?

Author

de Pouvourville, Gérard, primary, Armoiry, Xavier, additional, Lavorel, Aurélie, additional, Bilbault, Pascal, additional, Maugendre, Philippe, additional, Bensimon, Lionel, additional, Beziz, Dan, additional, Blin, Patrick, additional, Borget, Isabelle, additional, Bouée, Stéphane, additional, Collignon, Cécile, additional, Dervaux, Benoît, additional, Durand-Zaleski, Isabelle, additional, Julien, Marc, additional, de Léotoing, Lucie, additional, Majed, Laureen, additional, Martelli, Nicolas, additional, Séjourné, Thomas, additional, and Viprey, Marie, additional

Published
2023
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28. Cancer incidence and prevalence in cystic fibrosis patients with and without a lung transplant in France

Author

Rousset-Jablonski, Christine, primary, Dalon, Faustine, additional, Reynaud, Quitterie, additional, Lemonnier, Lydie, additional, Dehillotte, Clémence, additional, Jacoud, Flore, additional, Berard, Marjorie, additional, Viprey, Marie, additional, Van Ganse, Eric, additional, Durieu, Isabelle, additional, and Belhassen, Manon, additional

Published
2022
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30. Temporal Trend of Transient Ischemic Attack Management over a 10-Year Period: Data from the Rhône County, France

Author

Isnard, Florent, primary, Termoz, Anne, additional, Haesebaert, Julie, additional, Viprey, Marie, additional, Tazarourte, Karim, additional, Bravant, Estelle, additional, Perreton, Nathalie, additional, Cakmak, Serkan, additional, Meyran, Sylvie, additional, Ossedat, Catherine, additional, Ducreux, Bruno, additional, Pidoux, Christelle, additional, Bony, Thomas, additional, Douplat, Marion, additional, Potinet, Veronique, additional, Sigal, Alain, additional, Derex, Laurent, additional, Nighoghossian, Norbert, additional, Schott-Pethelaz, Anne-Marie, additional, and Mechtouff, Laura, additional

Published
2022
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31. Development and Validation of a Predictive Model of Hypovitaminosis D in General Adult Population: SCOPYD Study

Author

Viprey, Marie, primary, Merle, Blandine, additional, Riche, Benjamin, additional, Freyssenge, Julie, additional, Rippert, Pascal, additional, Chakir, Mohammed-Amine, additional, Thomas, Thierry, additional, Malochet-Guinamand, Sandrine, additional, Cortet, Bernard, additional, Breuil, Véronique, additional, Chapurlat, Roland, additional, Lafage Proust, Marie-Hélène, additional, Carlier, Marie-Christine, additional, Fassier, Jean-Baptiste, additional, Haesebaert, Julie, additional, Caillet, Pascal, additional, Rabilloud, Muriel, additional, and Schott, Anne-Marie, additional

Published
2021
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34. A Qualitative Study of Barriers and Facilitators to Adherence to Secondary Prevention Medications Among French Patients Suffering from Stroke and Transient Ischemic Attack

Author

Viprey,Marie, Gouillet,Maïlys, Puppo,Costanza, Termoz,Anne, Della Vecchia,Claire, Derex,Laurent, Haesebaert,Julie, Schott,Anne-Marie, and Préau,Marie

Subjects
Patient Preference and Adherence
Abstract

Marie Viprey,1,2 Maïlys Gouillet,3 Costanza Puppo,3 Anne Termoz,1,2 Claire Della Vecchia,2,3 Laurent Derex,2,4 Julie Haesebaert,1,2 Anne-Marie Schott,1,2 Marie Préau3 1Public Health Department, Hospices Civils de Lyon, Lyon, France; 2HESPER EA 7425, University of Lyon, University Claude Bernard Lyon 1, Lyon, France; 3GRePS, Lyon 2 University, Lyon, France; 4Comprehensive Stroke Center, Pierre Wertheimer Hospital, Hospices Civils de Lyon, Bron, FranceCorrespondence: Marie VipreyHospices Civils de Lyon, Pôle de Santé Publique, Bâtiment A, 6ème étage, 162, Avenue Lacassagne, Lyon 69003, FranceTel +33 4 72 11 53 02Email marie.viprey@chu-lyon.frPurpose: Secondary prevention medications (SPM) reduce the risk of ischemic stroke (IS) and transient ischemic attack (TIA) recurrence. However, approximately one-third of patients are estimated to be non-adherent. This qualitative study aimed to explore barriers and facilitators to adherence to SPM after IS or TIA.Patients and Methods: Thirty-six face-to-face semi-structured interviews were conducted with 14 TIA patients and 22 IS patients who self-administered their treatment 12 months after IS/TIA. A thematic analysis was performed.Results: Major facilitators to good adherence to SPM were the fear of stroke recurrence and the high level of trust in the prescribing physician. Barriers included a perceived lack and/or inappropriate timing of information about SPM, practical difficulties of taking some SPM (eg, inadequate packaging) and of implementing routines into their daily life.Conclusion: Information on SPM is inadequate in terms of quantity and timing both during the acute IS/TIA period and over the long term. Providing more tailor-made information at an opportune moment, in particular by promoting discussion with their general practitioner (GP) throughout the course of illness and recovery, is essential to ensure that patients are not left alone in the decision-making process regarding adherence to SPM.Keywords: medication adherence, stroke, transient ischemic attack, qualitative study

Published
2020

35. Prevalence of low health literacy levels in decompensated heart failure compared with acute myocardial infarction patients

Author

Perrin, Adèle, primary, Abdalla, Gergis, additional, Viprey, Marie, additional, Delahaye, François, additional, Mewton, Nathan, additional, Ovize, Michel, additional, Sebbag, Laurent, additional, Bochaton, Thomas, additional, Dima, Alexandra L., additional, Bravant, Estelle, additional, Schott, Anne‐Marie, additional, and Haesebaert, Julie, additional

Published
2021
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36. Unplanned readmission and survival after video-assisted thoracic surgery and open thoracotomy in patients with non-small-cell lung cancer: a 12-month nationwide cohort study

Author

Bouabdallah, Ilies, primary, Pauly, Vanessa, additional, Viprey, Marie, additional, Orleans, Veronica, additional, Fond, Guillaume, additional, Auquier, Pascal, additional, D'Journo, Xavier Benoit, additional, Boyer, Laurent, additional, and Thomas, Pascal Alexandre, additional

Published
2020
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38. Palliative and high-intensity end-of-life care in schizophrenia patients with lung cancer: results from a French national population-based study

Author

Viprey, Marie, primary, Pauly, Vanessa, additional, Salas, Sebastien, additional, Baumstarck, Karine, additional, Orleans, Veronica, additional, Llorca, Pierre-Michel, additional, Lancon, Christophe, additional, Auquier, Pascal, additional, Boyer, Laurent, additional, and Fond, Guillaume, additional

Published
2020
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40. Myocardial infarction: Economic, health, and social impacts on informal caregivers

Author

Rabier, Hugo, primary, Serrier, Hassan, additional, Schott, Anne-Marie, additional, Mewton, Nathan, additional, Margier, Jennifer, additional, Barral, Marine, additional, Dalaudiere, Jessica, additional, Fares, Asma, additional, Grguric, Gwen, additional, Guerre, Pascale, additional, Julien, Christell, additional, Viprey, Marie, additional, Ovize, Michel, additional, Nighoghossian, Norbert, additional, Duclos, Antoine, additional, and Colin, Cyrille, additional

Published
2020
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42. Choice of Initial Brain Imaging in Patients with Suspected Acute Stroke: STROKE69, a Population-Based Study

Author

Xue, Yufeng, primary, Haesebaert, Julie, additional, Derex, Laurent, additional, Viprey, Marie, additional, Termoz, Anne, additional, Della Vecchia, Claire, additional, Tassa, Ouazna, additional, Kerd, Hela, additional, Cakmak, Serkan, additional, Meyran, Sylvie, additional, Ducreux, Bruno, additional, Pidoux, Christelle, additional, Du Besset, Marc, additional, Bony, Thomas, additional, Gueugniaud, Pierre-Yves, additional, Douplat, Marion, additional, Potinet, Veronique, additional, Jacob, Xavier, additional, Sigal, Alain, additional, Tazarourte, Karim, additional, Lablanche, Christophe, additional, Melaine, Regis, additional, Nighoghossian, Norbert, additional, and Schott, Anne-Marie, additional

Published
2020
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43. Is there an association between access to a stroke reperfusion strategy and social deprivation? French population-based cohort study

Author

Perrin, Adèle, Freyssenge, Julie, Termoz, Anne, Viprey, Marie, Haesebaert, Julie, Derex, Laurent, Schott, Anne-Marie, Health Service and Performance Research (HESPER), Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon

Subjects
[SDV.EE.SANT]Life Sciences [q-bio]/Ecology, environment/Health, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2019
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44. Illness beliefs and emotional responses in mildly disabled stroke survivors: A qualitative study

Author

Della Vecchia, Claire, Préau, Marie, Carpentier, Camille, Viprey, Marie, Haesebaert, Julie, Termoz, Anne, Dima, Alexandra L., Schott, Anne-Marie, Bodescot, Myriam, MARVELOUS - - MARVELOUS2016 - ANR-16-RHUS-0009 - RHUS - VALID, Health Service and Performance Research (HESPER), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Groupe de Recherche en Psychologie Sociale (GRePS), Université Lumière - Lyon 2 (UL2), Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Pôle de Santé Publique [Lyon], Hospices Civils de Lyon (HCL), CDV was supported by a PhD grant from the Auvergne Rhône-Alpes region. This work was supported by the RHU MARVELOUS (ANR-16-RHUS-0009) of l’Université Claude Bernard Lyon 1 (UCBL), within the program 'Investissements d’Avenir' operated by the French National Research Agency (ANR), the 'Prevent’horizon' French Excellence Research Chair and the French institute of public health research (IRESP) (AAP Handicap 2015). This work was also supported by the ALLP., and ANR-16-RHUS-0009,MARVELOUS,MARVELOUS(2016)

Subjects
Male, Science, Cerebrovascular Diseases, Disabilities, Health Care Providers, Cognitive Neuroscience, Emotions, Culture, [SDV.NEU.PC] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior, Social Sciences, Pathology and Laboratory Medicine, Vascular Medicine, Signs and Symptoms, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Diagnostic Medicine, Surveys and Questionnaires, Mental Health and Psychiatry, Adaptation, Psychological, Medicine and Health Sciences, Psychology, Humans, Public and Occupational Health, Disabled Persons, Survivors, Fatigue, Qualitative Research, Aged, Cognitive Impairment, Aged, 80 and over, [SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior, Cognitive Neurology, Biology and Life Sciences, Middle Aged, [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Stroke, Health Care, Neurology, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, Medicine, Cognitive Science, Female, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Behavioral and Social Aspects of Health, Stress, Psychological, Research Article, Neuroscience
Abstract

International audience; BACKGROUND:As acute stroke services improve, more persons experience mild stroke and need to cope daily with hidden disabilities, which may be influenced by how they perceive stroke, cognitively and emotionally.OBJECTIVE:To investigate cognitive illness beliefs and emotional responses in persons with mild stroke and their possible influences on daily coping.METHODS:Semi-structured interviews were conducted with 24 persons with mild stroke, on average 7.5 months (±0.89) after stroke occurrence. A thematic analysis on verbatim transcripts was guided by the Common-Sense Model of Self-Regulation.RESULTS:All participants experienced difficulties constructing an illness identity at both acute and chronic phase. Behavioral risk factors were less accepted as causes of stroke. Lack (or inappropriate timing) of information from healthcare providers led to limited medication knowledge and low perceived control of stroke recurrence which generated anxiety, fear, and low involvement in coping. Participants who considered stroke a chronic condition experienced more difficulties. Perceived support from relatives and healthcare providers was beneficial for participation in recovery and health behaviour change.CONCLUSION:Despite having mildly disabilities, participants reported difficulties developing illness beliefs conducive to coping, and dealing with their emotional responses. These elements should be considered in tailored programs to improve coping with hidden disabilities post-stroke.

Published
2019
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45. Adherence to long-term therapies in cystic fibrosis: a French cross-sectional study linking prescribing, dispensing, and hospitalization data

Author

Rouzé,Héloïse, Viprey,Marie, Allemann,Samuel, Dima,Alexandra L, Caillet,Pascal, Denis,Angélique, Poupon-Bourdy,Stéphanie, Camara,Boubou, Llerena,Catherine, Reix,Philippe, Durieu,Isabelle, Reynaud,Quitterie, Touzet,Sandrine, Rouzé,Héloïse, Viprey,Marie, Allemann,Samuel, Dima,Alexandra L, Caillet,Pascal, Denis,Angélique, Poupon-Bourdy,Stéphanie, Camara,Boubou, Llerena,Catherine, Reix,Philippe, Durieu,Isabelle, Reynaud,Quitterie, and Touzet,Sandrine

Abstract

Héloïse Rouzé1,2, Marie Viprey1,2, Samuel Allemann2, Alexandra L Dima2, Pascal Caillet3, Angélique Denis1, Stéphanie Poupon-Bourdy1, Boubou Camara4, Catherine Llerena5, Philippe Reix6, Isabelle Durieu2,7, Quitterie Reynaud2,7, Sandrine Touzet1,2 1Public Health Department, Hospices Civils de Lyon, Lyon, France; 2HESPER Lab-EA 7425, Université de Lyon-Université Claude Bernard Lyon 1, Lyon, France; 3Department of Clinical Pharmacology, CHU de Nantes, Nantes, France; 4Pulmonary Department, Adult CF Center, CHU de Grenoble, Grenoble, France; 5Pediatric Pulmonology Department, Pediatric CF Center, CHU de Grenoble, Grenoble, France; 6Pediatric Pulmonology Department, Pediatric CF Center, Hôpital Femme-Mère-Enfant, Hospices Civils de Lyon, Lyon, France; 7Department of Internal Medicine, Adult Cystic Fibrosis Care Center, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon, FranceCorrespondence: Héloïse RouzéHospices Civils de Lyon, Pôle de Santé Publique, Bâtiment A, 6ème étage, 162 Avenue Lacassagne 69003 Lyon, FranceTel +33 47 211 5132Email heloise.rouze@chu-lyon.frBackground: Cystic fibrosis (CF) is a life-shortening genetic condition that usually affects several organs and involves significant treatment burden. Adherence to medication is important for successful CF management.Objective: To describe medication adherence according to age, therapeutic class, and pharmaceutical form in adults and children followed in four regional CF centers in France.Methods: We conducted a cross-sectional study with non-transplanted patients followed in two adult and two pediatric centers during 2015 who were covered by the French National Health Insurance (NHI). Sociodemographic, clinical, hospitalization, and prescription data were collected from patient medical records. Medication dispensations were e

Published
2019

46. Abnormal bleeding phenotype for mild haemophilia B patients with the p.Ile112Thr variation on the gene for factor IX.

Author

Row, Céline, Chamouni, Pierre, Berger, Claire, Lienhart, Anne, Meunier, Sandrine, Fretigny, Mathilde, Dalibard, Vincent, Viprey, Marie, Chambost, Hervé, Barbay, Virginie, and Bovet, Julien

Subjects
HEMORRHAGE, PHENOTYPES, HEMOPHILIA
Abstract

Further studies are needed to complete biological assessments of all patients, and a prospective study, particularly on patient evolution with prophylactic treatment, could be of interest. All the patients in our study presented their first joint bleed during childhood, even though spontaneous joint bleeds are unusual in mHB patients.2 In addition, some significant BE may have been underestimated. Four patients had arthrodesis/plasty, from 1 to 4 joint surgeries/patient, and the median age at first arthrodesis/plasty (total joint replacement, hip, knee, elbow) was 37 years (range 25-52 years). This is a retrospective cohort with patients from different French centre with clinical and biological data relying on patient treatment diaries and medical records. [Extracted from the article]

Published
2021
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47. Contextual determinants of participation after stroke: a systematic review of quantitative and qualitative studies.

Author

Della Vecchia, Claire, Viprey, Marie, Haesebaert, Julie, Termoz, Anne, Giroudon, Caroline, Dima, Alexandra, Rode, Gilles, Préau, Marie, and Schott, Anne-Marie

Subjects
*ONLINE information services, *PSYCHOLOGY information storage & retrieval systems, *PATIENT participation, *SOCIAL support, *HEALTH services accessibility, *SYSTEMATIC reviews, *MOTIVATION (Psychology), *SELF-perception, *CONVALESCENCE, *PATIENTS' attitudes, *SOCIOECONOMIC factors, *STROKE rehabilitation, *STROKE patients, *INTERPERSONAL relations, *MEDLINE, *ATTITUDES toward disabilities
Abstract

From a patient's perspective, participation is a major determinant of quality of life. We aimed to review contextual factors, both personal and environmental, potentially associated with post-stroke participation. PubMed, PsycINFO, and Web of Science were searched for original quantitative and qualitative studies that investigated contextual factors of post-stroke participation, measured participation as the primary outcome, and met inclusion criteria. Socio-demographic determinants were mostly unrelated with participation or showed discordant and inconclusive results. Although less investigated, psychosocial/psychological factors, particularly self-esteem and acceptance, were associated with participation in most studies. Motivation was found in qualitative studies, but discordant in quantitative ones. Environmental factors were even less investigated and mainly in qualitative studies among patients with communication disabilities. Among these, social support and attitude of others appeared to be major determinants of participation as well as physical environment and societal environment (services and polices). Personal factors, particularly psychological and psychosocial factors, were identified as positively associated with post-stroke participation. Environmental factors such as support, relationships, and positive attitudes towards patients were major facilitators of participation as well as physical environment and accessibility to appropriate services. Most of these factors are modifiable and should be addressed to improve patient participation. Psychosocial factors (motivational aspects, acceptance of a new condition, self-esteem) and environmental factors (social support, attitudes towards the patient, physical environment, access to health, social services and policies) were identified as determinants of post-stroke participation. A structured evaluation of determinants of participation may be used in clinical practice to propose appropriate support and then improve patients' recovery Programs to improve patients' psychosocial skills such as self-esteem, acceptance, motivation should be tested and implemented, and policies to develop appropriate services accessibility should be encouraged. [ABSTRACT FROM AUTHOR]

Published
2021
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48. Spatial stroke inequalities revealed thanks to Geographic Information System: data from STROKE 69 cohort

Author

Freyssenge, Julie, Florent, Renard, Tazarourte, Karim, Termoz, Anne, Haesebaert, Julie, Cakmak, S., Meyran, S., Ducreux, B., Pidoux, C., Bony, Thomas, DOUPLAT, Marion, POTINET, Véronique, Sigal, A., Viprey, Marie, El Khoury, Carlos, Derex, Laurent, Schott, Anne-Marie, Health Service and Performance Research (HESPER), Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon

Subjects
[SHS.GEO]Humanities and Social Sciences/Geography, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2018
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50. Endoscopic mucosal resection with anchoring of the snare tip: multicenter retrospective evaluation of effectiveness and safety

Author

Pioche, Mathieu, additional, Wallenhorst, Timothée, additional, Lepetit, Hugo, additional, Lépilliez, Vincent, additional, Rivory, Jérôme, additional, Legros, Romain, additional, Rostain, Florian, additional, Bianchi, Laurent, additional, Charissoux, Aurélie, additional, Hervieu, Valérie, additional, Moreno-Garcia, Maira, additional, Robinson, Philip, additional, Saurin, Jean-Christophe, additional, Ponchon, Thierry, additional, Viprey, Marie, additional, Roche, Laurent, additional, Subtil, Fabien, additional, and Jacques, Jérémie, additional

Published
2019
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