Search

Your search keyword '"Vipoma chemically induced"' showing total 2 results
Start Over Descriptor "Vipoma chemically induced"
2 results on '"Vipoma chemically induced"'

1. [Pancreatic endocrine tumor--from clinic to calcium sensing receptor].

Author

Imamura M

Subjects
Calcium metabolism, Gastrins blood, Humans, Infusions, Intra-Arterial, Pancreatic Function Tests methods, Receptors, G-Protein-Coupled, Receptors, Gastrointestinal Hormone metabolism, Secretin administration & dosage, Calcium-Binding Proteins physiology, Gastrinoma diagnosis, Gastrinoma metabolism, Glucagonoma diagnosis, Glucagonoma metabolism, Insulinoma diagnosis, Insulinoma metabolism, Pancreatic Neoplasms diagnosis, Pancreatic Neoplasms metabolism, Vipoma chemically induced, Vipoma metabolism
Published
2000

2. Pancreatic cholera syndrome due to a vasoactive intestinal polypeptide-producing tumor: further insights into the pathophysiology.

Author

Rood RP, DeLellis RA, Dayal Y, and Donowitz M

Subjects
Adult, Anal Canal physiopathology, Chlorine metabolism, Female, Humans, Intestine, Small metabolism, Pancreatic Neoplasms chemically induced, Pancreatic Neoplasms therapy, Potassium metabolism, Vasoactive Intestinal Peptide blood, Vipoma chemically induced, Vipoma therapy, Adenoma, Islet Cell physiopathology, Pancreatic Neoplasms physiopathology, Vasoactive Intestinal Peptide adverse effects, Vipoma physiopathology
Abstract

This case report describes a patient with pancreatic cholera caused by a vasoactive intestinal polypeptide-producing pancreatic tumor. The case presents several unusual characteristics of this disease. The primary tumor was a mucinous adenocarcinoma of the pancreas. The serum vasoactive intestinal polypeptide level of 2400 pmol/L is the highest reported. At this vasoactive intestinal polypeptide level, the somatostatin analogue SMS 201-995 at doses up to 2 mg/24 h did not control the 21 L/24 h stool output. Fecal incontinence due to a manometrically documented hypotonic internal anal sphincter occurred. Using surgically created stomas, the segmental gastrointestinal fluid and sodium losses were shown to be greatest from the jejunum, whereas potassium losses from the colon and small intestine were equal. The cellular mechanism for the small intestinal potassium secretion is not known.

Published
1988
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results