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21 results on '"Vincze, Sarah R."'

1. Dual-labeled anti-GD2 targeted probe for intraoperative molecular imaging of neuroblastoma

Author

Rosenblum, Lauren Taylor, Sever, ReidAnn E., Gilbert, Ryan, Guerrero, David, Vincze, Sarah R., Menendez, Dominic M., Birikorang, Peggy A., Rodgers, Mikayla R., Jaswal, Ambika Parmar, Vanover, Alexander C., Latoche, Joseph D., Cortez, Angel G., Day, Kathryn E., Foley, Lesley M., Sneiderman, Chaim T., Raphael, Itay, Hitchens, T. Kevin, Nedrow, Jessie R., Kohanbash, Gary, Edwards, W. Barry, and Malek, Marcus M.

Published
2024
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2. ImmunoPET imaging of TIGIT in the glioma microenvironment

Author

Vincze, Sarah R., Jaswal, Ambika P., Frederico, Stephen C., Nisnboym, Michal, Li, Bo, Xiong, Zujian, Sever, ReidAnn E., Sneiderman, Chaim T., Rodgers, Mikayla, Day, Kathryn E., Latoche, Joseph D., Foley, Lesley M., Hitchens, T. Kevin, Frederick, Robin, Patel, Ravi B., Hadjipanayis, Costas G., Raphael, Itay, Nedrow, Jessie R., Edwards, W. Barry, and Kohanbash, Gary

Published
2024
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3. Assessment of anti-CD69 antibody therapy alone or in combination with anti-PD-1 in murine GBM.

Author

Nisnboym, Michal, Sneiderman, Chaim T., Jaswal, Ambika P., Xiong, Zujian, Vincze, Sarah R., Sever, ReidAnn E., Zou, Han, Frederico, Stephen C., Agnihotri, Sameer, Hu, Baoli, Drappatz, Jan, Pollack, Ian F., Kohanbash, Gary, and Raphael, Itay

Subjects
TUMOR-infiltrating immune cells, KILLER cells, CELL populations, GLIOBLASTOMA multiforme, CELL death
Abstract

Background: Glioblastoma (GBM) is an aggressive cancer with limited treatment options. Immunotherapy targeting CD69, an early activation marker on T cells, has shown promise in preclinical models of non-CNS malignancies. This study investigates anti-CD69 therapy alone or in combination with anti-PD-1 in a preclinical GBM model. Research design and methods: CD69 expression in GBM patient tissues was analyzed using the TCGA database. Therapeutic efficacy of anti-CD69 was tested in a murine GBM model with different regimens. Immune cell populations in the tumor microenvironment (TME) were assessed by flow cytometry. Results: Increased CD69 expression was observed in GBM patients compared to normal brain tissue and was associated with worse prognosis. Anti-CD69 treatment reduced percentages of CD69+ immune cells but did not improve survival in GBM-bearing mice. Increased PD-1 expression on NK cells was observed following anti-CD69 treatment. Anti-CD69 treatment was not improved by the addition of anti-PD-1 in vivo. Conclusions: This is the first study evaluating anti-CD69 therapy in a preclinical GBM model. Despite promising preclinical data in other cancers, anti-CD69 monotherapy or combination therapy with anti-PD-1 did not improve survival in this GBM model. [ABSTRACT FROM AUTHOR]

Published
2025
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4. Supplementary Figure 9 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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5. Supplementary Figure 8 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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6. FIGURE 4 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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7. Supplementary Figure 2 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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8. Supplementary Figure 3 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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9. FIGURE 2 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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10. FIGURE 3 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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11. Supplementary Figure 4 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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12. Data from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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13. FIGURE 5 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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14. Supplementary Figure 7 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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15. Supplementary Figure 1 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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16. FIGURE 1 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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17. Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., additional, Xiong, Zujian, additional, Sneiderman, Chaim T., additional, Raphael, Rebecca A., additional, Li, Bo, additional, Jaswal, Ambika P., additional, Sever, ReidAnn E., additional, Day, Kathryn E., additional, LaToche, Joseph D., additional, Foley, Lesley M., additional, Karimi, Hanieh, additional, Hitchens, T. Kevin, additional, Agnihotri, Sameer, additional, Hu, Baoli, additional, Rajasundaram, Dhivyaa, additional, Anderson, Carolyn J., additional, Blumenthal, Deborah T., additional, Pearce, Thomas M., additional, Uttam, Shikhar, additional, Nedrow, Jessie R., additional, Panigrahy, Ashok, additional, Pollack, Ian F., additional, Lieberman, Frank S., additional, Drappatz, Jan, additional, Raphael, Itay, additional, Edwards, Wilson B., additional, and Kohanbash, Gary, additional

Published
2023
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18. Supplementary Figure 6 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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19. Supplementary Figure 5 from Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma

Author

Nisnboym, Michal, primary, Vincze, Sarah R., primary, Xiong, Zujian, primary, Sneiderman, Chaim T., primary, Raphael, Rebecca A., primary, Li, Bo, primary, Jaswal, Ambika P., primary, Sever, ReidAnn E., primary, Day, Kathryn E., primary, LaToche, Joseph D., primary, Foley, Lesley M., primary, Karimi, Hanieh, primary, Hitchens, T. Kevin, primary, Agnihotri, Sameer, primary, Hu, Baoli, primary, Rajasundaram, Dhivyaa, primary, Anderson, Carolyn J., primary, Blumenthal, Deborah T., primary, Pearce, Thomas M., primary, Uttam, Shikhar, primary, Nedrow, Jessie R., primary, Panigrahy, Ashok, primary, Pollack, Ian F., primary, Lieberman, Frank S., primary, Drappatz, Jan, primary, Raphael, Itay, primary, Edwards, Wilson B., primary, and Kohanbash, Gary, primary

Published
2023
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20. Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival following Immunotherapy in Murine GBM. (S17.009)

Author

Ziv, Michal Nisnboym, primary, Vincze, Sarah R., additional, Raphael, Itay, additional, Xiong, Zujian, additional, Sneiderman, Chaim T., additional, Raphael, Rebecca A., additional, Li, Bo, additional, Jaswal, Ambika P., additional, Sever, ReidAnn, additional, Day, Kathryn E., additional, LaToche, Joseph D., additional, Foley, Lesley M., additional, Hitchens, T. Kevin, additional, Agnihotri, Sameer, additional, Hu, Baoli, additional, Rajasundaram, Dhivyaa, additional, Anderson, Carolyn J., additional, Blumenthal, Deborah T., additional, Pearce, Thomas M., additional, Uttam, Shikhar, additional, Nedrow, Jessie R., additional, Panigrahy, Ashok, additional, Pollack, Ian F., additional, Lieberman, Frank S., additional, Drappatz, Jan, additional, Edwards, Wilson B., additional, and Kohanbash, Gary, additional

Published
2023
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