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BackgroundTranscatheter aortic valve replacement (TAVR) is a widely established alternative to surgery in intermediate- and high-risk patients. TAVR program development within the Veterans Affairs (VA) system has been previously described. However, national TAVR registries do not capture VA outcomes data, and few data have been reported regarding TAVR outcomes at lower-volume federal institutions. The study aim was to demonstrate the evolution of a successful VA TAVR program.MethodsA retrospective analysis was performed of the first 100 TAVR patients at San Francisco VA Medical Center. Mortality and major complications were evaluated.ResultsBetween 25th November 2013 and 31st August 2016, a total of 100 TAVR procedures was performed at the authors' institution. The mean patient age was 79.7 ± 8.7 years. Patients underwent TAVR via percutaneous-transfemoral (n = 90), surgical cutdown-transfemoral (n = 8), or transapical (n = 2) approaches. The valve systems employed were Edwards SAPIEN (n = 16), SAPIEN XT (n = 31), SAPIEN 3 (n = 23), and Medtronic CoreValve (n = 16) and CoreValve Evolut R (n = 14). The overall device success was 96%. TAVR-in-TAVR was required in the remaining 4% of patients, and was successful. All-cause procedural mortality was 1%. Complications included tamponade (1%), stroke (2%), temporary hemodialysis (1%), vascular injuries requiring intervention (4%), and permanent pacemaker implantation (14%). There were no conversions to surgical aortic valve replacement. Twenty-two (22%) patients had mild, two (2%) had moderate, and none (0%) had severe paravalvular leakage. The post-procedure aortic valve gradient by echocardiography was 8.6 ± 4.5 mmHg. Follow up was 100% complete and survival was 99%, 93%, and 89% at one, six, and 12 months, respectively.ConclusionsSuccessful outcomes were demonstrated for a VA TAVR program that compared favorably with benchmarks established by the National Transcatheter Valve Therapies Registry. These results provide a necessary transparency of TAVR outcomes at a federal institution.

One of the main sources of death in the globe is heart illness, and successful treatment depends on early detection. Heart illness is frequently diagnosed using the electrocardiogram (ECG) method, but data misclassification reduces its accuracy. In this paper, we develop an intelligent Low cost ECG device for automated classification of critical and non-essential information from an unbalanced ECG datas built in for smart IOT-based healthcare devices. The proposed method resolves the problem of data misclassification by transforming the unlabeled data into a balanced dataset. The proposed ECG device has the ability to help medical professionals recognize crucial ECG beats and make an exact diagnosis of cardiac illness and achieves 97.58% accuracy rate. The use of IOT technology makes it possible for remote tracking and real-time data analysis, which makes it simpler for healthcare professionals to watch patients' ECG data and make wise treatment choices. Overall, the low cost ECG device, with its quick and accurate detection powers that enhance patient outcomes, has the potential to revolutionize how cardiac disease is identified and managed in smart healthcare. [ABSTRACT FROM AUTHOR]

The present work deals with the understanding of the integrated experimental and theoretical study of the molecular structure and vibrational spectra of N-allyl-N-ethylformamide (NAEF). Density functional theory (DFT) calculations were used to study the subject molecule, N-allyl-N-ethylformamide (NAEF), utilising the B3LYP method and the basis set 6-311++G (d,p). Geometrical parameters and the structure of NAEF were computed such that global descriptors and reactive sites were obtained. Frontier's analysis of molecular orbital energy demonstrates that the molecule's charge exchange is considerably high. Non-linear optical properties of N-allyl-N-ethylformamide (NAEF) were computed and compared with the standard material of urea. The vibrational assignments were analysed for the existence of the probable functional groups and tabulated. The thermodynamic functions were computed at different temperatures and listed accordingly. NMR spectroscopy and quantum computational chemistry methods have been employed for the understanding of the structures of NAEF. Moreover, different techniques such as topological analysis and drug-likeness were utilised to determine the structure and other properties of NAEF. The molecular docking study could determine the residue with the highest docking score (lowest binding energy) and the most non-covalent interactions. [ABSTRACT FROM AUTHOR]

A novel organic compound derivativeof Benzothiazole, BFCPA[N-Substitued-1,3-benzothiazol-2pheny-2-[4-(furan-2-carbonyl)piperazin-1-phenyl] acetamidehas beensynthesizied and used as inhibitor on mild steelcorrosion in 1N and 2N HCl acidic medium.Using this inhibitor the rate of orrosion and inhibitor efficiency was analysed by mass loss data and electrochemical analysis. Byincreasing concentration of the inhibitor BFCPA exhibits good corrosion inhibition effectiveness less corrosion rate shows the electron donating property.The structure of BFCPA has been confirmed using various spectral studies. Based on adsorption studies it reveals Langmuir adsorption isotherm. [ABSTRACT FROM AUTHOR]

This paper provides technical method for poor eye sight persons or the blind and dumb person to communicate each other without any third person's help. The main parameters are hand gesture sensing, RF communication, sound output. The aim of the idea is to provide a gesture sensing gloves to the visually impaired one, a hand hold which shows a sound as output. This is done with help of flex sensors and sd-card module with speakers, whereas the flex sensing gloves detects the hand gestures and transmit the signals through a radiofrequency transmitter. This transmitted signal is received in the other and shows the signal as a sound output using speaker by the already recorded sounds in the sd-card module. They can communicate each other easily without anyone's help. [ABSTRACT FROM AUTHOR]

Nowadays the demand for power increases constantly. To meet the demands, production units were established all around the country. Until the electricity reaches our house it transforms both up and down many times, thus power fluctuation occurs in our house. To overcome this issue we have developed this device to identify the fault parameters and protect our household appliances using relay [ABSTRACT FROM AUTHOR]

Diabetes Mellitus in human beings is an inability to produce adequate insulin or process them which will cause a rise in blood sugar level. To maintain the blood glucose level check-up at a regular interval is required. The conventional method available currently involves pricking which irritates skin when done repeatedly. The objective of this paper is to overcome the painful process and to be noninvasive. Our proposed system is based on the NIR (near-infrared) spectroscopy method of a selected wavelength which is more sensitive to blood glucose. This helps to reduce the error factor and the system is implemented with machine learning to improve the efficiency of the output. [ABSTRACT FROM AUTHOR]

In this paper, an experimental study of the conventional solar still (CSS), the conventional solar still with glass cooling (CSSGC), the conventional solar still with basin heating (CSSBH), and the conventional solar still with glass cooling and basin heating (CSSGCBH) was carried out on the basis of the distilled water production, the energy efficiency (EnE), the exergy efficiency (ExE), and economic analysis. The CSSGC and CSSBH contain Peltier modules for cooling the glass and heating the basin. The evaporative heat transfer coefficient for all the experimental stills was calculated. The values of daily distilled water production from the CSSGCBH, CSSBH, CSSGC, and CSS were 4.56, 3.79, 2.49, and 1.89 kg/m², respectively. The daily distilled yield of the CSSBH and CSSGCBH were increased by 58.55% and 50.13%, respectively, as compared with the CSS. Moreover, the daily EnE and ExE of the CSSGCBH were 27.03% and 3.5%, respectively, whereas the EnE and ExE of the CSS were 10.88% and 1.3%, respectively. Furthermore, the cost of distilled water production was found to be 0.26, 0.35, 0.53, and 0.64 $/day for the CSS, CSSGC, CSSBH, and CSSGCBH, respectively, if the selling price of the distilled water was Rs10. [ABSTRACT FROM AUTHOR]

In this paper, a year around energy efficiency (EnE) and economic analysis of single slope solar still (SSSS), the single slope solar still with glass cooling (SSSSGC), the single slope solar still with basin heating (SSSSBH), and the single slope solar still with glass cooling and basin heating (SSSSGCBH) was carried out based on the distilled water production. The annual yield production from the SSSS, SSSSGC, SSSSBH, and SSSSGCBH were 476.16, 637.44, 970.24, and 1167.36 kg, respectively. The yearly yield produced from the SSSSBH and SSSSGCBH was increased by 50.92% and 59.21%, respectively, as compared with the SSSS. Moreover, the annual EnE of the SSSSGCBH was 28.75%. However, the EnE of the SSSS was 11.73%. Also, freshwater making cost is found to be 18.9, 24.9, 37.9, and 45.6 Rs/day for the SSSS, SSSSGC, SSSSBH, and SSSSGCBH, respectively, if the buying cost of freshwater is Rs 10. [ABSTRACT FROM AUTHOR]

Passive solar stills are used for solar distillation. But the yield of passive still is very low, and often fails to meet the demand. Water is one of the fundamental sources for the survival of mankind on the globe. As world having just a little measure of water assets for utilization purpose, individuals living in undeveloped countries and urban zones are getting affected by consuming dirty water that prompts water‐borne illness. Despite the fact that groundwater is accessible in little amount, it must be suitably treated before its utilization for domestic use. Salty water contains dissolved and undissolved substance, and henceforth, it is not advisable for family drinking purpose. To enhance the productivity of fresh water, several techniques were employed. Furthermore, increase in yield of fresh water depends on various environmental parameters and rate of condensation. In this article, a complete review of various methods employed to enhance the condensation rate on an active solar still has been presented. Solar still incorporated with the evacuated tube collectors (ETC) and thermo electric modules (TEM) increased the still effectiveness up to 68%. © 2018 American Institute of Chemical Engineers Environ Prog, 38: 286–296, 2019 [ABSTRACT FROM AUTHOR]