3,368 results on '"Villa, S."'
Search Results
2. Genus Field and Extended Genus Field of an Elementary Abelian Extension of Global Fields
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Hernandez B., Juan C. and Villa S., Gabriel D.
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- 2023
- Full Text
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3. Retrospective study of secondary implantation of retroiridial fixation lenses in patients without capsular support: functional results and complications
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Fernández Berdasco, K., Castro Navarro, J., González Castaño, C.n, Rodríguez Villa, S., and García Fernández, M.
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- 2022
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4. Estudio retrospectivo de implante secundario de lentes de fijación retroiridiana en pacientes sin soporte capsular: resultados funcionales y complicaciones
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Fernández Berdasco, K., Castro Navarro, J., González Castaño, C.n, Rodríguez Villa, S., and García Fernández, M.
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- 2022
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5. Phase coexistence and transitions between antiferromagnetic and ferromagnetic states in a synthetic antiferromagnet
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Barker, C. E. A., primary, Fallon, K., additional, Barton, C., additional, Haltz, E., additional, Almeida, T. P., additional, Villa, S., additional, Kirkbride, C., additional, Maccherozzi, F., additional, Sarpi, B., additional, Dhesi, S. S., additional, McGrouther, D., additional, McVitie, S., additional, Moore, T. A., additional, Kazakova, O., additional, and Marrows, C. H., additional
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- 2024
- Full Text
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6. Does multiparametric (mp) MRI and MRI-informed biopsy improve risk allocation of men at inclusion in active surveillance for low-risk prostatic cancer? Results of per-protocol population of the prospective single institution SPRINT trial
- Author
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Marenghi, C., primary, Badenchini, F., additional, Rancati, T., additional, Avuzzi, B., additional, Messina, A., additional, Casale, A., additional, Catanzaro, M.A., additional, Claps, M., additional, Casbarra, A., additional, Noris Chiorda, B., additional, Guadalupi, V., additional, Stellato, M., additional, Nazzani, S., additional, Stagni, S., additional, Cattaneo, L., additional, Macchi, A., additional, Villa, S., additional, Torelli, T., additional, Verzoni, E., additional, Tesone, A., additional, Procopio, G., additional, and Nicolai, N., additional
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- 2024
- Full Text
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7. Real world data of active surveillance protocols in low-risk prostate cancer. Intensity of follow-up may be reduced according to a 14 years’ experience
- Author
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Marenghi, C., primary, Badenchini, F., additional, Avuzzi, B., additional, Catanzaro, M.A., additional, Claps, M., additional, Casbarra, A., additional, Noris Chiorda, B., additional, Guadalupi, V., additional, Stellato, M., additional, Nazzani, S., additional, Stagn, S., additional, Cattaneo, L., additional, Casale, A., additional, Messina, A., additional, Villa, S., additional, Macchi, A., additional, Torelli, T., additional, Tesone, A., additional, Verzoni, E., additional, Procopio, G., additional, Rancati, T., additional, and Nicolai, N., additional
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- 2024
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8. Water Erosion, its Relationship to Total Suspended Solids and Water Quality in the Lower Basin of the Usumacinta River, Tabasco, Mexico
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G. Rodríguez-Martínez, I. Galaviz-Villa, S. Partida-Sedas, C.A. Sosa-Villalobos, R. de G. Bernal-Ramírez, V. Alcántara-Méndez and A. García-Saldaña
- Subjects
agricultural waste erosion risk loss of fertile soil water quality ,Environmental effects of industries and plants ,TD194-195 ,Science (General) ,Q1-390 - Abstract
Total suspended solids are an indicator of material constituted by sedimentable solids, suspended solids, and colloidal, whose origin is erosion, wastewater discharges, and agricultural waste. The objective of this research was to determine territorial water erosion, its relation with total suspended solids, and the water quality in the lower basin of the Usumacinta River in Tabasco. Three sampling points were established, located in the municipalities of Tenosique, Emiliano Zapata, and Jonuta, in the state of Tabasco. Water samples were collected during 12 monthly sampling campaigns in an annual cycle, and the total suspended solids were determined according to the provisions of the NMX-AA-034-SCFI-2015 standard. Water erosion was calculated based on the Universal Soil Loss Equation (USLE) and with the use of geographic information systems (GIS). The results obtained were statistically analyzed, finding that the measured maximum TSS concentrations are 130.92 mg.L-1 in Boca del Cerro, 165.28 mg.L-1 in Chablé, and 113.91 mg.L-1 in Jonuta which are within the permissible concentrations for protection of freshwater aquatic life and agricultural irrigation according to ecological criteria of water quality (CE-CCA-001/89), in Mexico. The lower basin of the Usumacinta River has areas with extreme erosion (990 tons.ha-1yr-1), with conditions that accelerate the erosion process, such as annual rainfall between 1805 mm and 2250 mm, clay soils located on slopes greater than 16%, and agricultural soils. These events cause loss of the soil fertile layer where agriculture is developed, also giving rise to the accelerated transport of suspended solids; which negatively alter the quality of the water of the Usumacinta River.
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- 2021
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9. Neurological and vascular complications of primary and secondary brain tumours: EANO-ESMO Clinical Practice Guidelines for prophylaxis, diagnosis, treatment and follow-up
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Roth, P., Pace, A., Le Rhun, E., Weller, M., Ay, C., Cohen-Jonathan Moyal, E., Coomans, M., Giusti, R., Jordan, K., Nishikawa, R., Winkler, F., Hong, J.T., Ruda, R., Villà, S., Taphoorn, M.J.B., Wick, W., and Preusser, M.
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- 2021
- Full Text
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10. Biomonitoring of human activities recovery following lockdown in a highly touristic Mediterranean Island using Mytilus galloprovincialis
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Della Torre, C, Villa, S, Chiarore, A, Cannavacciuolo, A, Rizzi, C, Musco, L, Nigro, L, Munari, M, Della Torre, C, Villa, S, Chiarore, A, Cannavacciuolo, A, Rizzi, C, Musco, L, Nigro, L, and Munari, M
- Abstract
Coastal waters face significant anthropogenic stress, particularly from tourism, exacerbating pollution, especially in areas like touristic islands. Ischia, the largest island in the Gulf of Naples and part of the Regno di Nettuno Marine Protected Area, suffers from pollution due to tourism and maritime traffic. During the initial SARS-CoV-2 lockdown from March to June 2020, Ischia was isolated, providing a unique opportunity to study pollutant release and its impact on coastal ecosystems. Adult Mytilus galloprovincialis mussels were transplanted to three sites on the island for active biomonitoring. Accumulation of chemicals in tissues and biomarkers related to metabolism, detoxification, and oxidative stress were measured. Results indicated that pollutants from daily activities entered the sea, affecting filter feeders. Translocated organisms showed modulated metabolic functions and biochemical changes, highlighting coastal vulnerability and calling for conservation efforts.
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- 2024
11. Clinical characteristics and outcomes of vaccinated patients hospitalised with SARS-CoV-2 breakthrough infection: Multi-IPV, a multicentre study in Northern Italy
- Author
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Lombardi, A, Villa, S, Colaneri, M, Scaglione, G, Bai, F, Varisco, B, Bono, V, Vena, A, Dentone, C, Russo, C, Tettamanti, M, Renisi, G, Viero, G, Azzarà, C, Mantero, M, Peyvandi, F, Bassetti, M, Marchetti, G, Muscatello, A, Nobili, A, Gori, A, Bandera, A, Bosari, S, Scudeller, L, Fusetti, G, Rusconi, L, Dell’Orto, S, Prati, D, Valenti, L, Giovannelli, S, Manunta, M, Lamorte, G, Ferarri, F, Gori., A, Mangioni, D, Alagna, L, Bozzi, G, Lombardi., A, Ungaro, R, Ancona, G, Mussa, M, Mariani, B, Bolis, M, Iannotti, N, Ludovisi, S, Comelli, A, Biscarini, S, Castelli, V, Palomba, E, Fava, M, Peri, C, Saltini, P, Itri, T, Ferroni, V, Pastore, V, Massafra, R, Liparoti, A, Muheberimana, T, Giommi, A, Bianco, R, Chitani, G, Bobbio, C, De Matteis, I, Bonomi, A, Gualtierotti, R, Ferrari, B, Rossio, R, Boasi, N, Pagliaro, E, Massimo, C, De Caro, M, Giachi, A, Montano, N, Vigone, B, Bellocchi, C, Carandina, A, Fiorelli, E, Melli, V, Tobaldini, E, Blasi, F, Aliberti, S, Spotti, M, Terranova, L, Misuraca, S, D’Adda, A, Della Fiore, S, Di Pasquale, M, Mantero., M, Contarini, M, Ori, M, Morlacchi, L, Rossetti, V, Gramegna, A, Pappalettera, M, Cavallini, M, Buscemi, A, Vicenzi, M, Rota, I, Costantino, G, Solbiati, M, Furlan, L, Mancarella, M, Colombo, G, Fanin, A, Passarella, M, Monzani, V, Canetta, C, Rovellini, A, Barbetta, L, Billi, F, Folli, C, Accordino, S, Maira, D, Hu, C, Motta, I, Scaramellini, N, Fracanzani, A, Lombardi, R, Cespiati, A, Cesari, M, Lucchi, T, Proietti, M, Calcaterra, L, Mandelli, C, Coppola, C, Cerizza, A, Pesenti, A, Grasselli, G, Galazzi, A, Nobili., A, Monti, I, Galbussera, A, Crisafulli, E, Girelli, D, Maroccia, A, Gabbiani, D, Busti, F, Vianello, A, Biondan, M, Sartori, F, Faverio, P, Pesci, A, Zucchetti, S, Bonfanti, P, Rossi, M, Beretta, I, Spolti, A, Harari, S, Elia, D, Cassandro, R, Caminati, A, Cipollone, F, Guagnano, M, D’Ardes, D, Rossi, I, Vezzani, F, Spanevello, A, Cherubino, F, Visca, D, Contoli, M, Papi, A, Morandi, L, Battistini, N, Moreo, G, Iannuzzi, P, Fumagalla, D, Leone, S, Lombardi, Andrea, Villa, Simone, Colaneri, Marta, Scaglione, Giovanni, Bai, Francesca, Varisco, Benedetta, Bono, Valeria, Vena, Antonio, Dentone, Chiara, Russo, Chiara, Tettamanti, Mauro, Renisi, Giulia, Viero, Giulia, Azzarà, Cecilia, Mantero, Marco, Peyvandi, Flora, Bassetti, Matteo, Marchetti, Giulia, Muscatello, Antonio, Nobili, Alessandro, Gori, Andrea, Bandera, Alessandra, Bosari, Silvano, Scudeller, Luigia, Fusetti, Giuliana, Rusconi, Laura, Dell’Orto, Silvia, Prati, Daniele, Valenti, Luca, Giovannelli, Silvia, Manunta, Maria, Lamorte, Giuseppe, Ferarri, Francesca, Gori. , Andrea, Mangioni, Davide, Alagna, Laura, Bozzi, Giorgio, Lombardi. , Andrea, Ungaro, Riccardo, Ancona, Giuseppe, Mussa, Marco, Mariani, Bianca Veronica, Bolis, Matteo, Iannotti, Nathalie, Ludovisi, Serena, Comelli, Agnese, Biscarini, Simona, Castelli, Valeria, Palomba, Emanuele, Fava, Marco, Peri, Carlo Alberto, Saltini, Paola, Itri, Teresa, Ferroni, Valentina, Pastore, Valeria, Massafra, Roberta, Liparoti, Arianna, Muheberimana, Toussaint, Giommi, Alessandro, Bianco, Rosaria, Chitani, Grazia Eliana, Bobbio, Chiara, De Matteis, Irene, Bonomi, Angelo Bianchi, Gualtierotti, Roberta, Ferrari, Barbara, Rossio, Raffaella, Boasi, Nadia, Pagliaro, Erica, Massimo, Costanza, De Caro, Michele, Giachi, Andrea, Montano, Nicola, Vigone, Barbara, Bellocchi, Chiara, Carandina, Angelica, Fiorelli, Elisa, Melli, Valerie, Tobaldini, Eleonora, Blasi, Francesco, Aliberti, Stefano, Spotti, Maura, Terranova, Leonardo, Misuraca, Sofia, D’Adda, Alice, Della Fiore, Silvia, Di Pasquale, Marta, Mantero. , Marco, Contarini, Martina, Ori, Margherita, Morlacchi, Letizia, Rossetti, Valeria, Gramegna, Andrea, Pappalettera, Maria, Cavallini, Mirta, Buscemi, Agata, Vicenzi, Marco, Rota, Irena, Costantino, Giorgio, Solbiati, Monica, Furlan, Ludovico, Mancarella, Marta, Colombo, Giulia, Colombo, Giorgio, Fanin, Alice, Passarella, Mariele, Monzani, Valter, Canetta, Ciro, Rovellini, Angelo, Barbetta, Laura, Billi, Filippo, Folli, Christian, Accordino, Silvia, Maira, Diletta, Hu, Cinzia Maria, Motta, Irene, Scaramellini, Natalia, Fracanzani, Anna Ludovica, Lombardi, Rosa, Cespiati, Annalisa, Cesari, Matteo, Lucchi, Tiziano, Proietti, Marco, Calcaterra, Laura, Mandelli, Clara, Coppola, Carlotta, Cerizza, Arturo, Pesenti, Antonio Maria, Grasselli, Giacomo, Galazzi, Alessandro, Nobili. , Alessandro, Monti, Igor, Galbussera, Alessia Antonella, Crisafulli, Ernesto, Girelli, Domenico, Maroccia, Alessio, Gabbiani, Daniele, Busti, Fabiana, Vianello, Alice, Biondan, Marta, Sartori, Filippo, Faverio, Paola, Pesci, Alberto, Zucchetti, Stefano, Bonfanti, Paolo, Rossi, Marianna, Beretta, Ilaria, Spolti, Anna, Harari, Sergio, Elia, Davide, Cassandro, Roberto, Caminati, Antonella, Cipollone, Francesco, Guagnano, Maria Teresa, D’Ardes, Damiano, Rossi, Ilaria, Vezzani, Francesca, Spanevello, Antonio, Cherubino, Francesca, Visca, Dina, Contoli, Marco, Papi, Alberto, Morandi, Luca, Battistini, Nicholas, Moreo, Guido Luigi, Iannuzzi, Pasqualina, Fumagalla, Daniele, Leone, Sara, Lombardi, A, Villa, S, Colaneri, M, Scaglione, G, Bai, F, Varisco, B, Bono, V, Vena, A, Dentone, C, Russo, C, Tettamanti, M, Renisi, G, Viero, G, Azzarà, C, Mantero, M, Peyvandi, F, Bassetti, M, Marchetti, G, Muscatello, A, Nobili, A, Gori, A, Bandera, A, Bosari, S, Scudeller, L, Fusetti, G, Rusconi, L, Dell’Orto, S, Prati, D, Valenti, L, Giovannelli, S, Manunta, M, Lamorte, G, Ferarri, F, Gori., A, Mangioni, D, Alagna, L, Bozzi, G, Lombardi., A, Ungaro, R, Ancona, G, Mussa, M, Mariani, B, Bolis, M, Iannotti, N, Ludovisi, S, Comelli, A, Biscarini, S, Castelli, V, Palomba, E, Fava, M, Peri, C, Saltini, P, Itri, T, Ferroni, V, Pastore, V, Massafra, R, Liparoti, A, Muheberimana, T, Giommi, A, Bianco, R, Chitani, G, Bobbio, C, De Matteis, I, Bonomi, A, Gualtierotti, R, Ferrari, B, Rossio, R, Boasi, N, Pagliaro, E, Massimo, C, De Caro, M, Giachi, A, Montano, N, Vigone, B, Bellocchi, C, Carandina, A, Fiorelli, E, Melli, V, Tobaldini, E, Blasi, F, Aliberti, S, Spotti, M, Terranova, L, Misuraca, S, D’Adda, A, Della Fiore, S, Di Pasquale, M, Mantero., M, Contarini, M, Ori, M, Morlacchi, L, Rossetti, V, Gramegna, A, Pappalettera, M, Cavallini, M, Buscemi, A, Vicenzi, M, Rota, I, Costantino, G, Solbiati, M, Furlan, L, Mancarella, M, Colombo, G, Fanin, A, Passarella, M, Monzani, V, Canetta, C, Rovellini, A, Barbetta, L, Billi, F, Folli, C, Accordino, S, Maira, D, Hu, C, Motta, I, Scaramellini, N, Fracanzani, A, Lombardi, R, Cespiati, A, Cesari, M, Lucchi, T, Proietti, M, Calcaterra, L, Mandelli, C, Coppola, C, Cerizza, A, Pesenti, A, Grasselli, G, Galazzi, A, Nobili., A, Monti, I, Galbussera, A, Crisafulli, E, Girelli, D, Maroccia, A, Gabbiani, D, Busti, F, Vianello, A, Biondan, M, Sartori, F, Faverio, P, Pesci, A, Zucchetti, S, Bonfanti, P, Rossi, M, Beretta, I, Spolti, A, Harari, S, Elia, D, Cassandro, R, Caminati, A, Cipollone, F, Guagnano, M, D’Ardes, D, Rossi, I, Vezzani, F, Spanevello, A, Cherubino, F, Visca, D, Contoli, M, Papi, A, Morandi, L, Battistini, N, Moreo, G, Iannuzzi, P, Fumagalla, D, Leone, S, Lombardi, Andrea, Villa, Simone, Colaneri, Marta, Scaglione, Giovanni, Bai, Francesca, Varisco, Benedetta, Bono, Valeria, Vena, Antonio, Dentone, Chiara, Russo, Chiara, Tettamanti, Mauro, Renisi, Giulia, Viero, Giulia, Azzarà, Cecilia, Mantero, Marco, Peyvandi, Flora, Bassetti, Matteo, Marchetti, Giulia, Muscatello, Antonio, Nobili, Alessandro, Gori, Andrea, Bandera, Alessandra, Bosari, Silvano, Scudeller, Luigia, Fusetti, Giuliana, Rusconi, Laura, Dell’Orto, Silvia, Prati, Daniele, Valenti, Luca, Giovannelli, Silvia, Manunta, Maria, Lamorte, Giuseppe, Ferarri, Francesca, Gori. , Andrea, Mangioni, Davide, Alagna, Laura, Bozzi, Giorgio, Lombardi. , Andrea, Ungaro, Riccardo, Ancona, Giuseppe, Mussa, Marco, Mariani, Bianca Veronica, Bolis, Matteo, Iannotti, Nathalie, Ludovisi, Serena, Comelli, Agnese, Biscarini, Simona, Castelli, Valeria, Palomba, Emanuele, Fava, Marco, Peri, Carlo Alberto, Saltini, Paola, Itri, Teresa, Ferroni, Valentina, Pastore, Valeria, Massafra, Roberta, Liparoti, Arianna, Muheberimana, Toussaint, Giommi, Alessandro, Bianco, Rosaria, Chitani, Grazia Eliana, Bobbio, Chiara, De Matteis, Irene, Bonomi, Angelo Bianchi, Gualtierotti, Roberta, Ferrari, Barbara, Rossio, Raffaella, Boasi, Nadia, Pagliaro, Erica, Massimo, Costanza, De Caro, Michele, Giachi, Andrea, Montano, Nicola, Vigone, Barbara, Bellocchi, Chiara, Carandina, Angelica, Fiorelli, Elisa, Melli, Valerie, Tobaldini, Eleonora, Blasi, Francesco, Aliberti, Stefano, Spotti, Maura, Terranova, Leonardo, Misuraca, Sofia, D’Adda, Alice, Della Fiore, Silvia, Di Pasquale, Marta, Mantero. , Marco, Contarini, Martina, Ori, Margherita, Morlacchi, Letizia, Rossetti, Valeria, Gramegna, Andrea, Pappalettera, Maria, Cavallini, Mirta, Buscemi, Agata, Vicenzi, Marco, Rota, Irena, Costantino, Giorgio, Solbiati, Monica, Furlan, Ludovico, Mancarella, Marta, Colombo, Giulia, Colombo, Giorgio, Fanin, Alice, Passarella, Mariele, Monzani, Valter, Canetta, Ciro, Rovellini, Angelo, Barbetta, Laura, Billi, Filippo, Folli, Christian, Accordino, Silvia, Maira, Diletta, Hu, Cinzia Maria, Motta, Irene, Scaramellini, Natalia, Fracanzani, Anna Ludovica, Lombardi, Rosa, Cespiati, Annalisa, Cesari, Matteo, Lucchi, Tiziano, Proietti, Marco, Calcaterra, Laura, Mandelli, Clara, Coppola, Carlotta, Cerizza, Arturo, Pesenti, Antonio Maria, Grasselli, Giacomo, Galazzi, Alessandro, Nobili. , Alessandro, Monti, Igor, Galbussera, Alessia Antonella, Crisafulli, Ernesto, Girelli, Domenico, Maroccia, Alessio, Gabbiani, Daniele, Busti, Fabiana, Vianello, Alice, Biondan, Marta, Sartori, Filippo, Faverio, Paola, Pesci, Alberto, Zucchetti, Stefano, Bonfanti, Paolo, Rossi, Marianna, Beretta, Ilaria, Spolti, Anna, Harari, Sergio, Elia, Davide, Cassandro, Roberto, Caminati, Antonella, Cipollone, Francesco, Guagnano, Maria Teresa, D’Ardes, Damiano, Rossi, Ilaria, Vezzani, Francesca, Spanevello, Antonio, Cherubino, Francesca, Visca, Dina, Contoli, Marco, Papi, Alberto, Morandi, Luca, Battistini, Nicholas, Moreo, Guido Luigi, Iannuzzi, Pasqualina, Fumagalla, Daniele, and Leone, Sara
- Abstract
Background: Despite the well-known efficacy of anti-COVID-19 vaccines in preventing morbidity and mortality, several vaccinated individuals are diagnosed with SARS-CoV-2 breakthrough infection, which might require hospitalisation. This multicentre, observational, and retrospective study aimed to investigate the clinical characteristics and outcomes of vaccinated vs. non-vaccinated patients, both hospitalised with SARS-CoV-2 infection in 3 major hospitals in Northern Italy. Methods: Data collection was retrospective, and paper and electronic medical records of adult patients with a diagnosed SARS-CoV-2 infection were pseudo-anonymised and analysed. Vaccinated and non-vaccinated individuals were manually paired, using a predetermined matching criterion (similar age, gender, and date of hospitalisation). Demographic, clinical, treatment, and outcome data were compared between groups differing by vaccination status using Pearson's Chi-square and Mann-Whitney tests. Moreover, multiple logistic regression analyses were performed to assess the impact of vaccination status on ICU admission or intra-hospital mortality. Results: Data from 360 patients were collected. Vaccinated patients presented with a higher prevalence of relevant comorbidities, like kidney replacement therapy or haematological malignancy, despite a milder clinical presentation at the first evaluation. Non-vaccinated patients required intensive care more often than their vaccinated counterparts (8.8% vs. 1.7%, p = 0.002). Contrariwise, no difference in intra-hospital mortality was observed between the two groups (19% vs. 20%, p = 0.853). These results were confirmed by multivariable logistic regressions, which showed that vaccination was significantly associated with decreased risk of ICU admission (aOR=0.172, 95%CI: 0.039–0.542, p = 0.007), but not of intra-hospital mortality (aOR=0.996, 95%CI: 0.582–1.703, p = 0.987). Conclusions: This study provides real-world data on vaccinated patients hospitalised wit
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- 2024
12. Association between physical activity and menstrual cycle disorders in young athletes
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Passoni, P, Inzoli, A, De Ponti, E, Polizzi, S, Ceccherelli, A, Fantauzzi, M, Procaccianti, C, Cattoni, A, Villa, S, Riva, A, Righetti, S, Landoni, F, Fruscio, R, Passoni, Paolo, Inzoli, Alessandra, De Ponti, Elena, Polizzi, Serena, Ceccherelli, Anna, Fantauzzi, Martina, Procaccianti, Chiara, Cattoni, Alessandro, Villa, Silvia, Riva, Anna, Righetti, Stefano, Landoni, Fabio, Fruscio, Robert, Passoni, P, Inzoli, A, De Ponti, E, Polizzi, S, Ceccherelli, A, Fantauzzi, M, Procaccianti, C, Cattoni, A, Villa, S, Riva, A, Righetti, S, Landoni, F, Fruscio, R, Passoni, Paolo, Inzoli, Alessandra, De Ponti, Elena, Polizzi, Serena, Ceccherelli, Anna, Fantauzzi, Martina, Procaccianti, Chiara, Cattoni, Alessandro, Villa, Silvia, Riva, Anna, Righetti, Stefano, Landoni, Fabio, and Fruscio, Robert
- Abstract
Our study aims at evaluating clinical predictors of menstrual cycle disorders in female athletes who compete in running disciplines. This is a prospective observational study. Women were recruited between January and May 2022. 53 patients were enrolled and completed a questionnaire about menstrual cycle, physical activity and food habits characteristics. 39,6% of women in our population had menstrual irregularities and reported a significantly higher number of kilometres run per week (67 vs 35, p:0.02). The number of kilometres run per week was associated with menstrual irregularities (for 10 km, OR 1,35; IC95% 1,05-1,73; p: 0,02) after adjusting for BMI, age, level of sport and caloric intake. The variable of “km run per week” appeared as a diagnostic indicator of irregular menstrual cycle with statistical significance (AUC ROC curve 0,71, IC95% 0,54-0,86, p-value = 0,01) and the cut off-of 65 km run per week is a good indicator of the presence of irregular menstrual cycle (sensitivity (SE) and specificity (SP) of 55% and 81,48%). Menstrual cycle disorders are very frequent in female athletes and the variable of km run per week may have a role in screening endurance athletes at high risk for them.
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- 2024
13. Inverse Fair Restrained Domination in the Corona of Two Graphs
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Verdad, Villa S., primary and Enriquez, Enrico L., additional
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- 2023
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14. The Physics of the B Factories
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Bevan, A. J., Golob, B., Mannel, Th., Prell, S., Yabsley, B. D., Abe, K., Aihara, H., Anulli, F., Arnaud, N., Aushev, T., Beneke, M., Beringer, J., Bianchi, F., Bigi, I. I., Bona, M., Brambilla, N., rodzicka, J. B, Chang, P., Charles, M. J., Cheng, C. H., Cheng, H. -Y., Chistov, R., Colangelo, P., Coleman, J. P., Drutskoy, A., Druzhinin, V. P., Eidelman, S., Eigen, G., Eisner, A. M., Faccini, R., Flood, K. T ., Gambino, P., Gaz, A., Gradl, W., Hayashii, H., Higuchi, T., Hulsbergen, W. D., Hurth, T., Iijima, T., Itoh, R., Jackson, P. D., Kass, R., Kolomensky, Yu. G., Kou, E., Križan, P., Kronfeld, A., Kumano, S., Kwon, Y. J., Latham, T. E., Leith, D. W. G. S., Lüth, V., Martinez-Vidal, F., Meadows, B. T., Mussa, R., Nakao, M., Nishida, S., Ocariz, J., Olsen, S. L., Pakhlov, P., Pakhlova, G., Palano, A., Pich, A., Playfer, S., Poluektov, A., Porter, F. C., Robertson, S. H., Roney, J. M., Roodman, A., Sakai, Y., Schwanda, C., Schwartz, A. J., Seidl, R., Sekula, S. 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S., Miyata, H., Miyazaki, Y., Moffitt, L. C., Mohapatra, A., Mohapatra, A. K., Mohapatra, D., Moll, A., Moloney, G. R., Mols, J. P., Mommsen, R. K., Monge, M. R., Monorchio, D., Moore, T. B., Moorhead, G. F., de Freitas, P. Mora, Morandin, M., Morgan, N., Morgan, S. E., Morganti, M., Morganti, S., Mori, S., Mori, T., Morii, M., Morris, J. P., Morsani, F., Morton, G. W., Moss, L. J., Mouly, J. P., Mount, R., Mueller, J., Müller-Pfefferkorn, R., Mugge, M., Muheim, F., Muir, A., Mullin, E., Munerato, M., Murakami, A., Murakami, T., Muramatsu, N., Musico, P., Nagai, I., Nagamine, T., Nagasaka, Y., Nagashima, Y., Nagayama, S., Nagel, M., Naisbit, M. T., Nakadaira, T., Nakahama, Y., Nakajima, M., Nakajima, T., Nakamura, I., Nakamura, T., Nakamura, T. T., Nakano, E., Nakayama, H., Nam, J. W., Narita, S., Narsky, I., Nash, J . A., Natkaniec, Z., Nauenberg, U., Nayak, M., Neal, H., Nedelkovska, E., Negrini, M., Neichi, K., Nelson, D., Nelson, S., Neri, N., Nesom, G., Neubauer, S., Newman-Coburn, D., Ng, C., Nguyen, X., Nicholson, H., Niebuhr, C., Nief, J. Y., Niiyama, M., Nikolich, M. B., Nisar, N. K., Nishimura, K., Nishio, Y., Nitoh, O., Nogowski, R., Noguchi, S., Nomura, T., Nordby, M., Nosochkov, Y., Novokhatski, A., Nozaki, S., Nozaki, T., Nugent, I. M., O'Grady, C. P., O'Neale, S. W., O'Neill, F. G., Oberhof, B., Oddone, P. J., Ofte, I., Ogawa, A., Ogawa, K., Ogawa, S., Ogawa, Y., Ohkubo, R., Ohmi, K., Ohnishi, Y., Ohno, F., Ohshima, T., Ohshima, Y., Ohuchi, N., Oide, K., Oishi, N., Okabe, T., Okazaki, N., Okazaki, T., Okuno, S., Olaiya, E. O., Olivas, A., Olley, P., Olsen, J., Ono, S., Onorato, G., Onuchin, A. P., Onuki, Y., Ooba, T., Orimoto, T. J., Oshima, T., Osipenkov, I. L., Ostrowicz, W., Oswald, C., Otto, S., Oyang, J., Oyanguren, A., Ozaki, H., Ozcan, V. E., Paar, H. P., Padoan, C., Paick, K., Palka, H., Pan, B., Pan, Y., Vazquez, W. Panduro, Panetta, J., Panova, A. I., Panvini, R. S., Panzenböck, E., Paoloni, E., Paolucci, P., Pappagallo, M., Paramesvaran, S., Park, C. S., Park, C. W., Park, H., Park, H. K., Park, K. S., Park, W., Parry, R. J., Parslow, N., Passaggio, S., Pastore, F. C., Patel, P. M., Patrignani, C., Patteri, P., Pavel, T., Pavlovich, J., Payne, D. J., Peak, L. S., Peimer, D. R., Pelizaeus, M., Pellegrini, R., Pelliccioni, M., Peng, C. C., Peng, J. C., Peng, K. C., Peng, T., Penichot, Y., Pennazzi, S., Pennington, M. R., Penny, R. C., Penzkofer, A., Perazzo, A., Perez, A., Perl, M., Pernicka, M., Perroud, J. -P., Peruzzi, I. M., Pestotnik, R., Peters, K., Peters, M., Petersen, B. A., Petersen, T. C., Petigura, E., Petrak, S., Petrella, A., Petrič, M., Petzold, A., Pia, M. G., Piatenko, T., Piccolo, D., Piccolo, M., Piemontese, L., Piemontese, M., Pierini, M., Pierson, S., Pioppi, M., Piredda, G., Pivk, M., Plaszczynski, S., Polci, F., Pompili, A., Poropat, P., Posocco, M., Potter, C. T., Potter, R. J. L., Prasad, V., Prebys, E., Prencipe, E., Prendki, J., Prepost, R., Prest, M., Prim, M., Pripstein, M., Prudent, X., Pruvot, S., Puccio, E. M. T., Purohit, M. V., Qi, N. D., Quinn, H., Raaf, J., Rabberman, R., Raffaelli, F., Ragghianti, G., Rahatlou, S., Rahimi, A. M., Rahmat, R., Rakitin, A. Y., Randle-Conde, A., Rankin, P., Rashevskaya, I., Ratkovsky, S., Raven, G., Re, V., Reep, M., Regensburger, J. J., Reidy, J., Reif, R., Reisert, B., Renard, C., Renga, F., Ricciardi, S., Richman, J. D., Ritchie, J. L., Ritter, M., Rivetta, C., Rizzo, G., Roat, C., Robbe, P., Roberts, D. A., Robertson, A. I., Robutti, E., Rodier, S., Rodriguez, D. M., Rodriguez, J. L., Rodriguez, R., Roe, N. A., Röhrken, M., Roethel, W., Rolquin, J., Romanov, L., Romosan, A., Ronan, M. T., Rong, G., Ronga, F. J., Roos, L., Root, N., Rosen, M., Rosenberg, E. I., Rossi, A., Rostomyan, A., Rotondo, M., Roussot, E., Roy, J., Rozanska, M., Rozen, Y., Rubin, A. E., Ruddick, W. O., Ruland, A. M., Rybicki, K., Ryd, A., Ryu, S., Ryuko, J., Sabik, S., Sacco, R., Saeed, M. A., Tehrani, F. Safai, Sagawa, H., Sahoo, H., Sahu, S., Saigo, M., Saito, T., Saitoh, S., Sakai, K., Sakamoto, H., Sakaue, H., Saleem, M., Salnikov, A. A., Salvati, E., Salvatore, F., Samuel, A., Sanders, D. A., Sanders, P., Sandilya, S., Sandrelli, F., Sands, W., Sands, W. R., Sanpei, M., Santel, D., Santelj, L., Santoro, V., Santroni, A., Sanuki, T., Sarangi, T. R., Saremi, S., Sarti, A., Sasaki, T., Sasao, N., Satapathy, M., Sato, Nobuhiko, Sato, Noriaki, Sato, Y., Satoyama, N., Satpathy, A., Savinov, V., Savvas, N., Saxton, O. H., Sayeed, K., Schaffner, S. F., Schalk, T., Schenk, S., Schieck, J. R., Schietinger, T., Schilling, C. J., Schindler, R. H., Schmid, S., Schmitz, R. E., Schmuecker, H., Schneider, O., Schnell, G., Schönmeier, P., Schofield, K. C., Schott, G., Schröder, H., Schram, M., Schubert, J., Schümann, J., Schultz, J., Schumm, B. A., Schune, M. H., Schwanke, U., Schwarz, H., Schwiening, J., Schwierz, R., Schwitters, R. F., Sciacca, C., Sciolla, G., Scott, I. J., Seeman, J., Seiden, A., Seitz, R., Seki, T., Sekiya, A. I., Semenov, S., Semmler, D., Sen, S., Senyo, K., Seon, O., Serbo, V. V., Serednyakov, S. I., Serfass, B., Serra, M., Serrano, J., Settai, Y., Seuster, R., Sevior, M. E., Shakhova, K. V., Shang, L., Shapkin, M., Sharma, V., Shebalin, V., Shelkov, V. G., Shen, B. C., Shen, D. Z., Shen, Y. T., Sherwood, D. J., Shibata, T., Shibata, T. A., Shibuya, H., Shidara, T., Shimada, K., Shimoyama, M., Shinomiya, S., Shiu, J. G., Shorthouse, H. W., Shpilinskaya, L. I., Sibidanov, A., Sicard, E., Sidorov, A., Sidorov, V., Siegle, V., Sigamani, M., Simani, M. C., Simard, M., Simi, G., Simon, F., Simonetto, F., Sinev, N. B., Singh, H., Singh, J. B., Sinha, R., Sitt, S., Skovpen, Yu. I., Sloane, R. J., Smerkol, P., Smith, A. J. S., Smith, D., Smith, D. S., Smith, J. G., Smol, A., Snoek, H. L., Snyder, A., So, R. Y., Sobie, R. J., Soderstrom, E., Soha, A., Sohn, Y. S., Sokoloff, M. D., Sokolov, A., Solagna, P., Solovieva, E., Soni, N., Sonnek, P., Sordini, V., Spaan, B., Spanier, S. M., Spencer, E., Speziali, V., Spitznagel, M., Spradlin, P., Staengle, H., Stamen, R., Stanek, M., Stanič, S., Stark, J., Steder, M., Steininger, H., Steinke, M., Stelzer, J., Stevanato, E., Stocchi, A., Stock, R., Stoeck, H., Stoker, D. P., Stroili, R., Strom, D., Strother, P., Strube, J., Stugu, B., Stypula, J., Su, D., Suda, R., Sugahara, R., Sugi, A., Sugimura, T., Sugiyama, A., Suitoh, S., Sullivan, M. K., Sumihama, M., Sumiyoshi, T., Summers, D. J., Sun, L., Sun, S., Sundermann, J. E., Sung, H. F., Susaki, Y., Sutcliffe, P., Suzuki, A., Suzuki, J., Suzuki, J. I., Suzuki, K., Suzuki, S., Suzuki, S. Y., Swain, J. E., Swain, S. K., T'Jampens, S., Tabata, M., Tackmann, K., Tajima, H., Tajima, O., Takahashi, K., Takahashi, S., Takahashi, T., Takasaki, F., Takayama, T., Takita, M., Tamai, K., Tamponi, U., Tamura, N., Tan, N., Tan, P., Tanabe, K., Tanabe, T., Tanaka, H. A., Tanaka, J., Tanaka, M., Tanaka, S., Tanaka, Y., Tanida, K., Taniguchi, N., Taras, P., Tasneem, N., Tatishvili, G., Tatomi, T., Tawada, M., Taylor, F., Taylor, G. N., Taylor, G. P., Telnov, V. I., Teodorescu, L., Ter-Antonyan, R., Teramoto, Y., Teytelman, D., Thérin, G., Thiebaux, Ch., Thiessen, D., Thomas, E. W., Thompson, J. M., Thorne, F., Tian, X. C., Tibbetts, M., Tikhomirov, I., Tinslay, J. S., Tiozzo, G., Tisserand, V., Tocut, V., Toki, W. H., Tomassini, E. W., Tomoto, M., Tomura, T., Torassa, E., Torrence, E., Tosi, S., Touramanis, C., Toussaint, J. C., Tovey, S. N., Trapani, P. P., Treadwell, E., Triggiani, G., Trincaz-Duvoid, S., Trischuk, W., Troost, D., Trunov, A., Tsai, K. L., Tsai, Y. T., Tsujita, Y., Tsukada, K., Tsukamoto, T., Tuggle, J. M., Tumanov, A., Tung, Y. W., Turnbull, L., Turner, J., Turri, M., Uchida, K., Uchida, M., Uchida, Y., Ueki, M., Ueno, K., Ujiie, N., Ulmer, K. A., Unno, Y., Urquijo, P., Ushiroda, Y., Usov, Y., Usseglio, M., Usuki, Y., Uwer, U., Va'vra, J., Vahsen, S. E., Vaitsas, G., Valassi, A., Vallazza, E., Vallereau, A., Vanhoefer, P., van Hoek, W. C., Van Hulse, C., van Winkle, D., Varner, G., Varnes, E. W., Varvell, K. E., Vasileiadis, G., Velikzhanin, Y. S., Verderi, M., Versillé, S., Vervink, K., Viaud, B., Vidal, P. B., Villa, S., Villanueva-Perez, P., Vinograd, E. L., Vitale, L., Vitug, G. M., Voß, C., Voci, C., Voena, C., Volk, A., von Wimmersperg-Toeller, J. H., Vorobyev, V., Vossen, A., Vuagnin, G., Vuosalo, C. O., Wacker, K., Wagner, A. P., Wagner, D. L., Wagner, G., Wagner, M. N., Wagner, S. R., Wagoner, D. E., Walker, D., Walkowiak, W., Wallom, D., Wang, C. C., Wang, C. H., Wang, J., Wang, J. G., Wang, K., Wang, L., Wang, L. L., Wang, P., Wang, T. J., Wang, W. F., Wang, X. L., Wang, Y. F., Wappler, F. R., Watanabe, M., Watson, A. T., Watson, J. E., Watson, N. K., Watt, M., Weatherall, J. H., Weaver, M., Weber, T., Wedd, R., Wei, J. T., Weidemann, A. W., Weinstein, A. J. R., Wenzel, W. A., West, C. A., West, C. G., West, T. J., White, E., White, R. M., Wicht, J., Widhalm, L., Wiechczynski, J., Wienands, U., Wilden, L., Wilder, M., Williams, D. C., Williams, G., Williams, J. C., Williams, K. M., Williams, M. I., Willocq, S. Y., Wilson, J. R., Wilson, M. G., Wilson, R. J., Winklmeier, F., Winstrom, L. O., Winter, M. A., Wisniewski, W. J., Wittgen, M., Wittlin, J., Wittmer, W., Wixted, R., Woch, A., Wogsland, B. J., Wong, Q. K., Wray, B. C., Wren, A. C., Wright, D. M., Wu, C. H., Wu, J., Wu, S. L., Wulsin, H. W., Xella, S. M., Xie, Q. L., Xie, Y., Xu, Z. Z., Yèche, Ch., Yamada, Y., Yamaga, M., Yamaguchi, A., Yamaguchi, H., Yamaki, T., Yamamoto, H., Yamamoto, N., Yamamoto, R. K., Yamamoto, S., Yamanaka, T., Yamaoka, H., Yamaoka, J., Yamaoka, Y., Yamashita, Y., Yamauchi, M., Yan, D. S., Yan, Y., Yanai, H., Yanaka, S., Yang, H., Yang, R., Yang, S., Yarritu, A. K., Yashchenko, S., Yashima, J., Yasin, Z., Yasu, Y., Ye, S. W., Yeh, P., Yi, J. I., Yi, K., Yi, M., Yin, Z. W., Ying, J., Yocky, G., Yokoyama, K., Yokoyama, M., Yokoyama, T., Yoshida, K., Yoshida, M., Yoshimura, Y., Young, C. C., Yu, C. X., Yu, Z., Yuan, C. Z., Yuan, Y., Yumiceva, F. X., Yusa, Y., Yushkov, A. N., Yuta, H., Zacek, V., Zain, S. B., Zallo, A., Zambito, S., Zander, D., Zang, S. L., Zanin, D., Zaslavsky, B. G., Zeng, Q. L., Zghiche, A., Zhang, B., Zhang, J., Zhang, L., Zhang, L. M., Zhang, S. Q., Zhang, Z. P., Zhao, H. W., Zhao, M., Zhao, Z. G., Zheng, Y., Zheng, Y. H., Zheng, Z. P., Zhilich, V., Zhou, P., Zhu, R. Y., Zhu, Y. S., Zhu, Z. M., Zhulanov, V., Ziegler, T., Ziegler, V., Zioulas, G., Zisman, M., Zito, M., Zürcher, D., Zwahlen, N., Zyukova, O., Živko, T., and Žontar, D.
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High Energy Physics - Experiment ,High Energy Physics - Phenomenology - Abstract
This work is on the Physics of the B Factories. Part A of this book contains a brief description of the SLAC and KEK B Factories as well as their detectors, BaBar and Belle, and data taking related issues. Part B discusses tools and methods used by the experiments in order to obtain results. The results themselves can be found in Part C. Please note that version 3 on the archive is the auxiliary version of the Physics of the B Factories book. This uses the notation alpha, beta, gamma for the angles of the Unitarity Triangle. The nominal version uses the notation phi_1, phi_2 and phi_3. Please cite this work as Eur. Phys. J. C74 (2014) 3026., Comment: 928 pages, version 3 (arXiv:1406.6311v3) corresponds to the alpha, beta, gamma version of the book, the other versions use the phi1, phi2, phi3 notation
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- 2014
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15. Advantages and Challenges of Tailored Regimens for Drug-Resistant Tuberculosis: A StopTB Italia Look into the Future
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Riccardi N, Villa S, Alagna R, Giacomelli A, Saderi L, Cirillo DM, Besozzi G, Sotgiu G, and Codecasa L
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tuberculosis ,drug-resistance ,treatment ,tailored ,stoptb. ,Infectious and parasitic diseases ,RC109-216 - Abstract
Niccolò Riccardi,1,2,* Simone Villa,1,3,* Riccardo Alagna,1,4 Andrea Giacomelli,1,5 Laura Saderi,1,6 Daniela Maria Cirillo,1,4 Giorgio Besozzi,1 Giovanni Sotgiu,1,6 Luigi Codecasa1,7 1StopTB Italia Onlus, Milan 20159, Italy; 2Department of Infectious - Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Verona 37024, Italy; 3Centre for Multidisciplinary Research in Health Science, University of Milan, Milan 20122, Italy; 4IRCCS San Raffaele Scientific Institute, Milan 20132, Italy; 5III Infectious Diseases Unit, ASST Fatebenefratelli Sacco, Milan 20157, Italy; 6Clinical Epidemiology and Medical Statistics Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari 07100, Italy; 7Regional TB Reference Centre, Istituto Villa Marelli, Niguarda Hospital, Milan 20159, Italy*These authors contributed equally to this workCorrespondence: Niccolò RiccardiDepartment of Infectious - Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Via Don A. Sempreboni N.5, 37024, Negrar di Valpolicella, Verona, ItalyTel +39 045 601 6420Email niccolo.riccardi@yahoo.itAbstract: The emerge of drug-resistant tuberculosis (TB) strain in recent decades is hampering the efforts of the international community to eliminate the disease worldwide. The World Health Organization (WHO) has drafted many strategies to achieve this ambitious goal. In the very beginning, the aim was to standardize inadequate regimens used in many countries and, thereafter, evolved to tackle the social determinants which hinder TB elimination. However, following the path of narrowing the clinical vision to deal with TB, there is an increased need to personalize the treatment considering both patients and pathogen unique characteristics. In our narrative review, we report the advantages and the backwards in developing a method to implement the concept of precision medicine to the treatment of TB. In this dissertation, we highlight the importance to address different aspects of the diseases encompassing the host and pathogen features, as well as the needs to further implement an adequate follow-up based on the available resources. Nevertheless, many things may hamper the vision of precision medicine in TB, such as the complexity and the costs to develop novel compounds and the costs related to global-scale implementation of patient-centered follow-up. To achieve the ambitious goal of TB elimination, a radical change in TB treatment is needed in order to give a more comprehensive approach based both on patients’ peculiarities and driven by drug susceptibility tests and whole-genome sequencing.Keywords: tuberculosis, drug-resistance, treatment, tailored, StopTB
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- 2020
16. A planar polarized MYO6-DOCK7-RAC1 axis promotes tissue fluidification in mammary epithelia
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Menin, L, Weber, J, Villa, S, Martini, E, Maspero, E, Niño, C, Cancila, V, Poli, A, Maiuri, P, Palamidessi, A, Frittoli, E, Bianchi, F, Tripodo, C, Walters, K, Giavazzi, F, Scita, G, Polo, S, Menin L., Weber J., Villa S., Martini E., Maspero E., Niño C. A., Cancila V., Poli A., Maiuri P., Palamidessi A., Frittoli E., Bianchi F., Tripodo C., Walters K. J., Giavazzi F., Scita G., Polo S., Menin, L, Weber, J, Villa, S, Martini, E, Maspero, E, Niño, C, Cancila, V, Poli, A, Maiuri, P, Palamidessi, A, Frittoli, E, Bianchi, F, Tripodo, C, Walters, K, Giavazzi, F, Scita, G, Polo, S, Menin L., Weber J., Villa S., Martini E., Maspero E., Niño C. A., Cancila V., Poli A., Maiuri P., Palamidessi A., Frittoli E., Bianchi F., Tripodo C., Walters K. J., Giavazzi F., Scita G., and Polo S.
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Tissue fluidification and collective motility are pivotal in regulating embryonic morphogenesis, wound heal-ing, and tumor metastasis. These processes frequently require that each cell constituent of a tissue coordi-nates its migration activity and directed motion through the oriented extension of lamellipodium cell protru-sions, promoted by RAC1 activity. While the upstream RAC1 regulators in individual migratory cells or leader cells during invasion or wound healing are well characterized, how RAC1 is controlled in follower cells re-mains unknown. Here, we identify a MYO6-DOCK7 axis essential for spatially restricting RAC1 activity in a planar polarized fashion in model tissue monolayers. The MYO6-DOCK7 axis specifically controls the exten-sion of cryptic lamellipodia required to drive tissue fluidification and cooperative-mode motion in otherwise solid and static carcinoma cell collectives.
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- 2023
17. Silent Contamination: The State of the Art, Knowledge Gaps, and a Preliminary Risk Assessment of Tire Particles in Urban Parks
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Federico, L, Masseroni, A, Rizzi, C, Villa, S, Federico L., Masseroni A., Rizzi C., Villa S., Federico, L, Masseroni, A, Rizzi, C, Villa, S, Federico L., Masseroni A., Rizzi C., and Villa S.
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Tire particles (TPs) are one of the main emission sources of micro- and nano-plastics into the environment. Although most TPs are deposited in the soil or in the sediments of freshwater and although they have been demonstrated to accumulate in organisms, most research has focused on the toxicity of leachate, neglecting the potential effects of particles and their ecotoxicological impact on the environment. In addition, studies have focused on the impact on aquatic systems and there are many gaps in the biological and ecotoxicological information on the possible harmful effects of the particles on edaphic fauna, despite the soil ecosystem becoming a large plastic sink. The aim of the present study is to review the environmental contamination of TPs, paying particular attention to the composition and degradation of tires (I), transport and deposition in different environments, especially in soil (II), the toxicological effects on edaphic fauna (III), potential markers and detection in environmental samples for monitoring (IV), preliminary risk characterization, using Forlanini Urban Park, Milan (Italy), as an example of an urban park (V), and risk mitigation measures as possible future proposals for sustainability (VI).
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- 2023
18. Improvement in quality of life after botulinum toxin injection for temporomandibular disorder
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Villa, S., Raoul, G., Machuron, F., Ferri, J., and Nicot, R.
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- 2019
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19. Linezolid for infective endocarditis: A structured approach based on a national database experience
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Muñoz, P., De la Villa, S., Martínez-Sellés, M., Goenaga, M.A., Reviejo-Jaka, K., Revillas, F. Arnáiz de las, García-Cuello, L., Hidalgo-Tenorio, C., Rodríguez-Esteban, M.A., Antorrena, I., Castelo-Corral, L., García-Vázquez, E., De la Torre, J., and Bouza, E.
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- 2021
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20. M. tuberculosis salicylate synthase MbtI in complex with methyl-AMT (new crystal form)
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Mori, M., primary, Villa, S., additional, Meneghetti, M., additional, and Bellinzoni, M., additional
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- 2023
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21. Grade reclassification during active surveillance in low risk prostate cancer men selected with an MRI-informed biopsy
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Marenghi, C., primary, Badenchini, F., additional, Avuzzi, B., additional, Catanzaro, M.A., additional, Claps, M., additional, Casbarra, A., additional, Noris Chiorda, B., additional, Guadalupi, V., additional, Stellato, M., additional, Nazzani, S., additional, Stagni, S., additional, Cattaneo, L., additional, Casale, A., additional, Messina, A., additional, Villa, S., additional, Macchi, A., additional, Torelli, T., additional, Verzoni, E., additional, Procopio, G., additional, Rancati, T., additional, and Nicolai, N., additional
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- 2023
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22. Magnetically Targeted Delivery of Sorafenib Through Magnetic Solid Lipid Nanoparticles Towards Treatment of Hepatocellular Carcinoma
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Vischio, F., primary, Depalo, N., additional, Iacobazzi, R. M., additional, Scavo, M. P., additional, Villa, S., additional, Canepa, F., additional, Lee, S. Hee, additional, Lee, B. Chul, additional, Fanizza, E., additional, Arduino, I., additional, Laquintana, V., additional, Lopalco, A., additional, Lopedota, A., additional, Cutrignelli, A., additional, Striccoli, M., additional, Agostiano, A., additional, Denora, N., additional, and Curri, M. L., additional
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- 2020
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23. Conservative Treatments for Tendinopathy
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Tencone, F., Della Villa, S., Giannini, A., Canata, Gian Luigi, editor, d'Hooghe, Pieter, editor, and Hunt, Kenneth J., editor
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- 2017
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24. Magnetically Targeted Delivery of Sorafenib Through Magnetic Solid Lipid Nanoparticles Towards Treatment of Hepatocellular Carcinoma
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Vischio, F., Depalo, N., Iacobazzi, R. M., Scavo, M. P., Villa, S., Canepa, F., Lee, S. Hee, Lee, B. Chul, Fanizza, E., Arduino, I., Laquintana, V., Lopalco, A., Lopedota, A., Cutrignelli, A., Striccoli, M., Agostiano, A., Denora, N., Curri, M. L., Sindona, Giovanni, editor, Banoub, Joseph H., editor, and Di Gioia, Maria Luisa, editor
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- 2020
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25. Search for the decay B0 to gamma gamma
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The Belle Collaboration and Villa, S.
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High Energy Physics - Experiment - Abstract
The rare decay B0 -> gamma gamma is searched for in 104 fb^-1 of data, corresponding to 111 x 10^6 BBar pairs, collected with the Belle detector at the KEKB asymmetric-energy e+ e- collider. No evidence for the signal is found, and an upper limit of 6.2 x 10^-7 at 90% confidence level is set for the corresponding branching fraction., Comment: 7 pages, 3 figures, accepted for publication by Phys. Rev. D
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- 2005
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26. The Global Electroweak Fit
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Villa, S.
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High Energy Physics - Phenomenology - Abstract
We report the results of the global electroweak fit, with emphasis on the most recent results which served as input of the fit. The output of the fit sets also limits on the Standard Model Higgs mass., Comment: 5 pages, 3 figures. to be published in the proceedings of IFAE, Parma, April 2002
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- 2002
27. Tissue fluidification promotes a cGAS–STING cytosolic DNA response in invasive breast cancer
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Frittoli E., Palamidessi A., Iannelli F., Zanardi F., Villa S., Barzaghi L., Abdo H., Cancila V., Beznoussenko G. V., Della Chiara G., Pagani M., Malinverno C., Bhattacharya D., Pisati F., Yu W., Galimberti V., Bonizzi G., Martini E., Mironov A. A., Gioia U., Ascione F., Li Q., Havas K., Magni S., Lavagnino Z., Pennacchio F. A., Maiuri P., Caponi S., Mattarelli M., Martino S., d'Adda di Fagagna F., Rossi C., Lucioni M., Tancredi R., Pedrazzoli P., Vecchione A., Petrini C., Ferrari F., Lanzuolo C., Bertalot G., Nader G., Foiani M., Piel M., Cerbino R., Giavazzi F., Tripodo C., Scita G., Frittoli, E., Palamidessi, A., Iannelli, F., Zanardi, F., Villa, S., Barzaghi, L., Abdo, H., Cancila, V., Beznoussenko, G. V., Della Chiara, G., Pagani, M., Malinverno, C., Bhattacharya, D., Pisati, F., Yu, W., Galimberti, V., Bonizzi, G., Martini, E., Mironov, A. A., Gioia, U., Ascione, F., Li, Q., Havas, K., Magni, S., Lavagnino, Z., Pennacchio, F. A., Maiuri, P., Caponi, S., Mattarelli, M., Martino, S., d'Adda di Fagagna, F., Rossi, C., Lucioni, M., Tancredi, R., Pedrazzoli, P., Vecchione, A., Petrini, C., Ferrari, F., Lanzuolo, C., Bertalot, G., Nader, G., Foiani, M., Piel, M., Cerbino, R., Giavazzi, F., Tripodo, C., and Scita, G.
- Abstract
The process in which locally confined epithelial malignancies progressively evolve into invasive cancers is often promoted by unjamming, a phase transition from a solid-like to a liquid-like state, which occurs in various tissues. Whether this tissue-level mechanical transition impacts phenotypes during carcinoma progression remains unclear. Here we report that the large fluctuations in cell density that accompany unjamming result in repeated mechanical deformations of cells and nuclei. This triggers a cellular mechano-protective mechanism involving an increase in nuclear size and rigidity, heterochromatin redistribution and remodelling of the perinuclear actin architecture into actin rings. The chronic strains and stresses associated with unjamming together with the reduction of Lamin B1 levels eventually result in DNA damage and nuclear envelope ruptures, with the release of cytosolic DNA that activates a cGAS-STING (cyclic GMP-AMP synthase-signalling adaptor stimulator of interferon genes)-dependent cytosolic DNA response gene program. This mechanically driven transcriptional rewiring ultimately alters the cell state, with the emergence of malignant traits, including epithelial-to-mesenchymal plasticity phenotypes and chemoresistance in invasive breast carcinoma.
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- 2023
28. Can native shrubs facilitate the early establishment of contrasted co-occurring oaks in Mediterranean grazed areas?
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Costa, A., Villa, S., Alonso, P., García-Rodríguez, J.A., Martín, F.J., Martínez-Ruiz, C., and Fernández-Santos, B.
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- 2017
29. Prediction of local and metastatic recurrence in solitary fibrous tumor: construction of a risk calculator in a multicenter cohort from the French Sarcoma Group (FSG) database
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Salas, S., Resseguier, N., Blay, J.Y., Le Cesne, A., Italiano, A., Chevreau, C., Rosset, P., Isambert, N., Soulie, P., Cupissol, D., Delcambre, C., Bay, J.O., Dubray-Longeras, P., Krengli, M., De Bari, B., Villa, S., Kaanders, J.H.A.M., Torrente, S., Pasquier, D., Thariat, J.O., Myroslav, L., Sole, C.V., Dincbas, H.F., Habboush, J.Y., Zilli, T., Dragan, T., Khanfir, K., Ugurluer, G., Cena, T., Duffaud, F., Penel, N., Bertucci, F., Ranchere-Vince, D., Terrier, P., Bonvalot, S., Macagno, N., Lemoine, C., Lae, M., Coindre, J.M., and Bouvier, C.
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- 2017
- Full Text
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30. Intralesional rituximab in primary conjunctival follicular lymphoma relapsed
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Rodríguez Villa, S., Ruiz Rodríguez, M.J., and Vargas Pabón, M.
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- 2017
- Full Text
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31. Rituximab intralesional como tratamiento de linfoma folicular primario de conjuntiva recidivante
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Rodríguez Villa, S., Ruiz Rodríguez, M.J., and Vargas Pabón, M.
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- 2017
- Full Text
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32. Modulazione del fenotipo cellulare indotto da radioterapia ipofrazionata in un modello murino di glioma
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Granata, S, Valtorta, S, Rainone, P, De Pretis, S, Diprima, S, Zerbetto, F, Villa, S, Di Muzio, N, Moresco, RM, Granata, S, Valtorta, S, Rainone, P, De Pretis, S, Diprima, S, Zerbetto, F, Villa, S, Di Muzio, N, and Moresco, R
- Subjects
NGS, Radiotherapy, scRNA-Seq, in vivo, glioblastoma - Abstract
Negli ultimi anni nuove tecnologie, che prendono il nome di Next-generation sequecing (NGS), sono state sviluppate al fine di stabilire il profilo genetico delle singole cellule, permettendo un nuovo approccio allo studio della diversità delle cellule immunitarie. Una di queste tecnologie è il sequenziamento dell'RNA a livello di cellula singola (scRNA-Seq). In questo studio abbiamo valutato l’effetto a lungo termine (21 giorni) dell’esposizione a radioterapia ipo-frazionata (RT) sulle cellule non tumorali in un modello murino di glioma di alto grado. Topi maschi del ceppo C57Bl/6 sono stati divisi in due gruppi e sottoposti a trattamento sham o mediante RT. Due animali per gruppo sono stati selezionati per effettuare il scRNA-Seq a livello del tessuto cerebrale. Per ciascun’analisi 10mila cellule sono state processate tramite la piattaforma Chromium (10X) utilizzando la libreria “Chromium Single Cell 3’”. Le matrici di espressione genica grezza generate con CellRanger (v3.0.2) sono state analizzate mediante il software Seurat R (v4.0.1) e includendo nell’analisi solo le cellule che esprimevano almeno 700 geni (6'931 e 8'186 cellule per veicolo e RT rispettivamente). Le cellule tumorali sono state identificate mediante genotipizzazione utilizzando il softaware Souporcell e rimosse dall'analisi. La tecnica scRNA-Seq ha rivelato la presenza di 25 differenti cluster cellulari (con esclusione di 4 cluster di cellule tumorali). I cluster identificati includevano fenotipi differenti cellule di origine mieloide (macrofagi e microglia), cellule dendritiche, linfociti B e T, natural killer (NK) più cellule endoteliali, podociti, oligodendrociti, neuroni e astrociti. A 21 giorni dall’esposizione a RT si assiste ad un aumento relativo di macrofagi con riduzione dell’espressione di Tgfb1 e TSPO ma non di TREM2 e di linfociti T, soprattutto regolatori, con aumento dell’espressione di trascritti legati a infiammazione e metabolismo. Infine, il trattamento radioterapico induce un aumento di marcatori di reattività astrocitaria, stress cellulare e neuroprotezione come Lgal3, Nupr1 e Igfbpl1. In conclusione, a tre settimane dalla somministrazione di RT sono ancora presenti modificazioni della risposta immunitaria legata a macrofagi e linfociti e modificazioni a carico degli astrociti probabilmente legate al danno cellulare.
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- 2023
33. Author Correction: Tissue fluidification promotes a cGAS–STING cytosolic DNA response in invasive breast cancer (Nature Materials, (2022), 10.1038/s41563-022-01431-x)
- Author
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Frittoli E., Palamidessi A., Iannelli F., Zanardi F., Villa S., Barzaghi L., Abdo H., Cancila V., Beznoussenko G. V., Della Chiara G., Pagani M., Malinverno C., Bhattacharya D., Pisati F., Yu W., Galimberti V., Bonizzi G., Martini E., Mironov A. A., Gioia U., Ascione F., Li Q., Havas K., Magni S., Lavagnino Z., Pennacchio F. A., Maiuri P., Caponi S., Mattarelli M., Martino S., d'Adda di Fagagna F., Rossi C., Lucioni M., Tancredi R., Pedrazzoli P., Vecchione A., Petrini C., Ferrari F., Lanzuolo C., Bertalot G., Nader G., Foiani M., Piel M., Cerbino R., Giavazzi F., Tripodo C., Scita G., Frittoli E., Palamidessi A., Iannelli F., Zanardi F., Villa S., Barzaghi L., Abdo H., Cancila V., Beznoussenko G.V., Della Chiara G., Pagani M., Malinverno C., Bhattacharya D., Pisati F., Yu W., Galimberti V., Bonizzi G., Martini E., Mironov A.A., Gioia U., Ascione F., Li Q., Havas K., Magni S., Lavagnino Z., Pennacchio F.A., Maiuri P., Caponi S., Mattarelli M., Martino S., d'Adda di Fagagna F., Rossi C., Lucioni M., Tancredi R., Pedrazzoli P., Vecchione A., Petrini C., Ferrari F., Lanzuolo C., Bertalot G., Nader G., Foiani M., Piel M., Cerbino R., Giavazzi F., Tripodo C., and Scita G.
- Subjects
c-gas ,Settore MED/05 - Patologia Clinica ,Settore MED/08 - Anatomia Patologica - Abstract
In the version of this article initially published, the first name of Flora Ascione was listed as “Floriana”; the error has been corrected in the HTML and PDF versions of the article.
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- 2023
34. Integrazione della catena logistica nel settore sanitario: quali strategie sono implementate?
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Belvedere, V., Laratro, S., Villa, S, Belvedere V. (ORCID:0000-0002-7748-5152), Laratro S., Villa S (ORCID:0000-0001-8111-3098), Belvedere, V., Laratro, S., Villa, S, Belvedere V. (ORCID:0000-0002-7748-5152), Laratro S., and Villa S (ORCID:0000-0001-8111-3098)
- Abstract
Lo studio fa luce sulle strategie di integrazione della logistica dei beni nel settore sanitario. La presente ricerca focalizza l'attenzione sulla partnership tra fornitori e aziende sanitarie e si pone l’obiettivo di rispondere a tre diverse domande: i) quali sono le strategie di integrazione che le organizzazioni sanitarie cercano di attuare con i propri fornitori?; ii) quali sono i vantaggi e le barriere delle diverse strategie di integrazione?; iii) quali sono le condizioni organizzative per una strategia di integrazione di successo? I dati sono stati raccolti mediante la somministrazione di un questionario rivolto ai responsabili acquisti/logistici delle aziende sanitarie del centro-nord Italia. La popolazione target finale per questa analisi era costituita da 135 unità. Il tasso di risposta è stato del 46%. Le evidenze mostrano un notevole grado di maturità delle organizzazioni sanitarie. I progetti di integrazione tendono in genere a prendere di mira gli elementi più complessi: (i) dispositivi medici e (ii) materiali per sale operatorie. Le organizzazioni sanitarie cercano partner industriali in grado di offrire elevati standard di qualità dei servizi logistici. La standardizzazione, il commitment del top management e la rilevanza strategica della funzione logistica sono ampiamente considerati come aspetti chiave per l'implementazione di successo di questi progetti.
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- 2022
35. Integrated Exposure and Algal Ecotoxicological Assessments of Effluents from Secondary and Advanced-Tertiary Wastewater-Treatment Plants
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Palumbo, M, Russo, S, Polesello, S, Guzzella, L, Roscioli, C, Marziali, L, Valsecchi, L, Cappelli, F, Pascariello, S, Tasselli, S, Villa, S, Peruzzo, M, Culatina, S, Bellotti, G, Turolla, A, Antonelli, M, Malpei, F, Valsecchi, S, Palumbo M. T., Russo S., Polesello S., Guzzella L., Roscioli C., Marziali L., Valsecchi L., Cappelli F., Pascariello S., Tasselli S., Villa S., Peruzzo M., Culatina S., Bellotti G., Turolla A., Antonelli M., Malpei F., Valsecchi S., Palumbo, M, Russo, S, Polesello, S, Guzzella, L, Roscioli, C, Marziali, L, Valsecchi, L, Cappelli, F, Pascariello, S, Tasselli, S, Villa, S, Peruzzo, M, Culatina, S, Bellotti, G, Turolla, A, Antonelli, M, Malpei, F, Valsecchi, S, Palumbo M. T., Russo S., Polesello S., Guzzella L., Roscioli C., Marziali L., Valsecchi L., Cappelli F., Pascariello S., Tasselli S., Villa S., Peruzzo M., Culatina S., Bellotti G., Turolla A., Antonelli M., Malpei F., and Valsecchi S.
- Abstract
The great concern over the environmental impact of wastewaters has led to the designing of advanced treatment processes to upgrade conventional treatment plants and achieve a significant reduction of contaminants in receiving waters. In the present study we combined chemical and ecotoxicological analyses, aiming to evaluate the reduction of toxicity effects associated with the removal of micropollutants and to define the contribution of the detected compounds to the overall toxicity of the mixtures in a series of wastewater effluents collected from a secondary treatment (OUT 2) and from a tertiary activated carbon treatment (OUT 3) plant. The target compounds were selected after a screening procedure among pharmaceuticals, musk fragrances, and trace metals. The classical algal growth inhibition test was conducted on the original effluent samples and on different fractions obtained by solid-phase extraction (SPE) treatment. A good accordance was found between the removal of toxicity (30%–80%) and organic compounds (70%–80%) after the tertiary treatment, suggesting its high efficiency to improve the wastewater quality. The discrepancy between the contribution to the overall toxicity of the nonadsorbable compounds (i.e., inorganic or very polar organic compounds) as experimentally measured by the SPE bioassays (18%–76%) and calculated by the concentration addition approach (>97%) could be mitigated by including the bioavailability correction in metal-toxicity modeling of wastewater mixtures. For the organic compounds, the toxic equivalency method enabled us to quantify the portion of toxicity explained by the detected chemicals in both OUT 2 (82%–104%) and OUT 3 (5%–57%), validating the selection of the target molecules. The applied integrating approach could be implemented by the inclusion of both additional target chemicals and toxicity endpoints. Environ Toxicol Chem 2022;41:2404–2419.
- Published
- 2022
36. PO-1490 Prostate cancer nodal relapse: impact of CRPC and previous RT on salvage ENRT+PET guided SIB outcome
- Author
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Fodor, A., primary, Deantoni, C., additional, Giannini, L., additional, Ferrario, F., additional, Villa, S., additional, Mangili, P., additional, Perna, L., additional, Broggi, S., additional, Dell'Oca, I., additional, Zerbetto, F., additional, Chissotti, C., additional, Midulla, M., additional, Torrisi, M., additional, Longobardi, B., additional, Castriconi, R., additional, Del Vecchio, A., additional, Cozzarini, C., additional, Fiorino, C., additional, and Di Muzio, N., additional
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- 2023
- Full Text
- View/download PDF
37. PO-1355 Impact of lymphopenia in patients with esophageal cancer after neoadjuvant chemoradiotherapy
- Author
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SLIM, N., primary, Chissotti, C., additional, Passoni, P., additional, Tummineri, R., additional, Zerbetto, F., additional, Torrisi, M., additional, Giannini, L., additional, Midulla, M., additional, Ferrario, F., additional, Villa, S., additional, Mazza, E., additional, Albarello, L., additional, De Cobelli, F., additional, Rosati, R., additional, Cascinu, S., additional, and Di Muzio, N.G., additional
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- 2023
- Full Text
- View/download PDF
38. Reducing the burden of TB among migrants to low TB incidence countries
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Spruijt, I., primary, Erkens, C., additional, Greenaway, C., additional, Mulder, C., additional, Raviglione, M., additional, Villa, S., additional, Zenner, D., additional, and Lönnroth, K., additional
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- 2023
- Full Text
- View/download PDF
39. Corrigendum to “A qualitative exploration of undergraduate nursing students' experience of emotional safety for learning during their clinical practice” [Nurse Educ. Today. 121 2023, 105,673]
- Author
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Steven, A., primary, Rossi, S., additional, Dasso, N., additional, Napolitano, F., additional, Grosso, A., additional, Villa, S., additional, Aleo, G., additional, Catania, G., additional, Sasso, L., additional, Zanini, M., additional, and Bagnasco, A., additional
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- 2023
- Full Text
- View/download PDF
40. Towards a Haptic Taxonomy of Emotions: Exploring Vibrotactile Stimulation in the Dorsal Region
- Author
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Villa, S, Nguyen, TD, Tag, B, Machulla, TK, Schmidt, A, Niess, J, Villa, S, Nguyen, TD, Tag, B, Machulla, TK, Schmidt, A, and Niess, J
- Published
- 2023
41. Fire safety of BIPV : International mapping of accredited and R&D facilities in the context of codes and standards 2023
- Author
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Boddaert, S., Bonomo, P, Eder, G, Fjellgaard Mikalsen, Ragni, Ishii, H, Kim, J-T, Ko, Y, Kovacs, Peter, Li, Tian, Olano, X, Parolini, F, Qi, D, Shabunko, V, Slooff, L, Stølen, Reidar, Valencia, D, Villa, S, Wilson, H R, Yang, R, Zang, Y, Boddaert, S., Bonomo, P, Eder, G, Fjellgaard Mikalsen, Ragni, Ishii, H, Kim, J-T, Ko, Y, Kovacs, Peter, Li, Tian, Olano, X, Parolini, F, Qi, D, Shabunko, V, Slooff, L, Stølen, Reidar, Valencia, D, Villa, S, Wilson, H R, Yang, R, and Zang, Y
- Abstract
The objective of Task 15 of the IEA Photovoltaic Power Systems Programme is to create an enabling framework to accelerate the penetration of BIPV products in the global market of renewables, resulting in an equal playing field for BIPV products, BAPV products and regular building envelope components, respecting mandatory issues, aesthetic issues, reliability issues, and financial issues. Subtask E of Task 15 is focused on pre-normative international research on BIPV characterisation methods and activity E.3 is dedicated to fire safety of BIPV modules and installations.
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- 2023
42. Glacier foreland insect uptake synthetic compounds: an emerging environmental concern
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Lencioni, V, Rizzi, C, Gobbi, M, Mustoni, A, Villa, S, Valeria Lencioni, Cristiana Rizzi, Mauro Gobbi, Andrea Mustoni, Sara Villa, Lencioni, V, Rizzi, C, Gobbi, M, Mustoni, A, Villa, S, Valeria Lencioni, Cristiana Rizzi, Mauro Gobbi, Andrea Mustoni, and Sara Villa
- Abstract
Pesticides, synthetic fragrances and polycyclic aromatic hydrocarbons contaminated two glacier-fed streams (Amola, Mandrone) and one spring (Grostè) in the Italian Alps. Ten compounds (chlorpyrifos (CPY), chlorpyrifos-methyl (CPY-m), galaxolide (HHCB), tonalide (AHTN), fluorene (Flu), phenanthrene (Phen), anthracene (Ant), fluoranthene (Fl), pyrene (Pyr), benzo[a]anthracene (BaA)) accumulated in aquatic larvae of chironomids (Diamesa steinboecki, D. latitarsis, D. bertrami, D. tonsa, D. zernyi, Pseudokiefferiella parva, Orthocladiinae) and tipulids. Their tissue concentrations (detected by gas chromatography coupled with mass spectrometry) ranged from 1.1 ± 0.1 ng/g d.w. (= dry weight) (CPY-m in D. tonsa from Amola) to 68.0 ± 9.1 ng/g d.w. (Pyr in D. steinboecki from Mandrone). HHCB, AHTN, and CPY, with one exception, were accumulated by all aquatic insects. Six compounds (CPY, CPY-m, HHCB, AHTN, Fl, Pyr) also contaminated carabids (Nebria germarii, N. castanea, N. jockischii) predating adults of merolimnic insects. Their tissue concentrations ranged from 1.1 ± 0.3 ng/g d.w. (CPY-m in N. germarii from Mandrone) to 84.6 ± 0.3 ng/g d.w. (HHCB in N. castanea from Grostè). HHCB and AHTN were accumulated by all Nebria species. Intersite and interspecies differences were observed, which might be attributed to different environmental contamination levels. There was a stronger similarity between species from the same site than among the same species from different sites, suggesting that uptake is not species specific. At all sites, the concentration of xenobiotics was higher in larvae than in water and comparable or higher in carabids than in larvae from the same site, suggesting trophic transfer by emerging aquatic insects to their riparian predators.
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- 2023
43. Web-based surveillance of respiratory infection outbreaks: retrospective analysis of Italian COVID-19 epidemic waves using Google Trends
- Author
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Porcu, G, Chen, Y, Bonaugurio, A, Villa, S, Riva, L, Messina, V, Bagarella, G, Maistrello, M, Leoni, O, Cereda, D, Matone, F, Gori, A, Corrao, G, Porcu, Gloria, Chen, Yu Xi, Bonaugurio, Andrea Stella, Villa, Simone, Riva, Leonardo, Messina, Vincenzina, Bagarella, Giorgio, Maistrello, Mauro, Leoni, Olivia, Cereda, Danilo, Matone, Fulvio, Gori, Andrea, Corrao, Giovanni, Porcu, G, Chen, Y, Bonaugurio, A, Villa, S, Riva, L, Messina, V, Bagarella, G, Maistrello, M, Leoni, O, Cereda, D, Matone, F, Gori, A, Corrao, G, Porcu, Gloria, Chen, Yu Xi, Bonaugurio, Andrea Stella, Villa, Simone, Riva, Leonardo, Messina, Vincenzina, Bagarella, Giorgio, Maistrello, Mauro, Leoni, Olivia, Cereda, Danilo, Matone, Fulvio, Gori, Andrea, and Corrao, Giovanni
- Abstract
Introduction: Large-scale diagnostic testing has been proven insufficient to promptly monitor the spread of the Coronavirus disease 2019. Electronic resources may provide better insight into the early detection of epidemics. We aimed to retrospectively explore whether the Google search volume has been useful in detecting Severe Acute Respiratory Syndrome Coronavirus outbreaks early compared to the swab-based surveillance system. Methods: The Google Trends website was used by applying the research to three Italian regions (Lombardy, Marche, and Sicily), covering 16 million Italian citizens. An autoregressive-moving-average model was fitted, and residual charts were plotted to detect outliers in weekly searches of five keywords. Signals that occurred during periods labelled as free from epidemics were used to measure Positive Predictive Values and False Negative Rates in anticipating the epidemic wave occurrence. Results: Signals from “fever,” “cough,” and “sore throat” showed better performance than those from “loss of smell” and “loss of taste.” More than 80% of true epidemic waves were detected early by the occurrence of at least an outlier signal in Lombardy, although this implies a 20% false alarm signals. Performance was poorer for Sicily and Marche. Conclusion: Monitoring the volume of Google searches can be a valuable tool for early detection of respiratory infectious disease outbreaks, particularly in areas with high access to home internet. The inclusion of web-based syndromic keywords is promising as it could facilitate the containment of COVID-19 and perhaps other unknown infectious diseases in the future.
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- 2023
44. Gestione in Service dei Flussi Logistici in Ospedale: perché e a quali condizioni?
- Author
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Belvedere, Valeria, Cervi, L., D’Agnese, G., Damele, A., Palumbo, Michele, Pellegrino, Rossella, Polimeni, J., Russo, A., Villa, Stefano, Belvedere V. (ORCID:0000-0002-7748-5152), Palumbo M., Pellegrino R. (ORCID:0009-0002-9277-4937), Villa S. (ORCID:0000-0001-8111-3098), Belvedere, Valeria, Cervi, L., D’Agnese, G., Damele, A., Palumbo, Michele, Pellegrino, Rossella, Polimeni, J., Russo, A., Villa, Stefano, Belvedere V. (ORCID:0000-0002-7748-5152), Palumbo M., Pellegrino R. (ORCID:0009-0002-9277-4937), and Villa S. (ORCID:0000-0001-8111-3098)
- Abstract
Il presente studio, utilizzando differenti metodi d’indagine (survey, interviste semi-strutturate e studio osservazionale), analizza le condizioni organizzative e l'impatto sulla performance del modello di gestione in service dei flussi logistici.
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- 2023
45. How to avoid rapid carbon dioxide changes at the start of veno-venous extracorporeal membrane oxygenation: Role of end-tidal CO2 monitoring
- Author
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Giani, M, Lucchini, A, Magni, G, Villa, S, Rona, R, Fumagalli, R, Foti, G, Giani, Marco, Lucchini, Alberto, Magni, Gloria, Villa, Silvia, Rona, Roberto, Fumagalli, Roberto, Foti, Giuseppe, Giani, M, Lucchini, A, Magni, G, Villa, S, Rona, R, Fumagalli, R, Foti, G, Giani, Marco, Lucchini, Alberto, Magni, Gloria, Villa, Silvia, Rona, Roberto, Fumagalli, Roberto, and Foti, Giuseppe
- Abstract
Background: Venovenous ECMO is a lifesaving technique for patients with severe respiratory failure. Management of carbon dioxide (CO2) levels at ECMO start is crucial, as recent studies found an association between rapid CO2 shifts and increased incidence of neurological complications. Purpose: To describe the role of end tidal CO2 (etCO2) monitoring at the ECMO start to minimize carbon dioxide shifts. Research design: Retrospective cohort study. Methods: We performed a retrospective analysis of patients who started venovenous ECMO support at our institution between 2011 and 2021. We analysed the minute-by-minute variations of etCO2, ventilatory parameters and arterial blood gas before and after the ECMO start. Results: 36 patients with a complete dataset of parameters were included. After the ECMO start, minute ventilation was progressively reduced from 10.8±;3.3 to 2.9±1.2 L/min (p<0.001). etCO2 did not vary significantly (baseline 37±10 vs 35±9 mmHg 20 minutes after ECMO start, p = 0.36). Despite a stable etCO2 level, a mild drop of arterial CO2 tension (9.5 mmHg, corresponding to a 18% change) was recorded at the first ABG sampled after the ECMO start. No patient developed neurological complications after the ECMO commencement. Conclusion: etCO2 monitoring during ECMO start is feasible and allows to adjust gas flow and ventilator settings to limit changes in arterial CO2 levels.
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- 2023
46. Bioconcentration and cellular effects of emerging contaminants in sponges from Maldivian coral reefs: A managing tool for sustainable tourism
- Author
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Rizzi, C, Seveso, D, De Grandis, C, Montalbetti, E, Lancini, S, Galli, P, Villa, S, Rizzi, C, Seveso, D, De Grandis, C, Montalbetti, E, Lancini, S, Galli, P, and Villa, S
- Abstract
Tourism is the main income source for the Maldives, but concurrently, it represents a growing threat to its marine ecosystem. Here, we monitored the bioaccumulation of 15 emerging contaminants (ECs) in the Maldivian reef sponges Spheciospongia vagabunda collected in two resort islands (Athuruga and Thudufushi, Ari Atoll) and an inhabited island (Magoodhoo, Faafu Atoll), and we analysed their impact on different sponge cellular stress biomarkers. Caffeine and the insect repellent DEET were detected in sponges of all the islands, whereas the antibiotic erythromycin and the UV filter 4-methylbenzylidene camphor were found in resort islands only. Although concentrations were approximately a few ng/g d.w., we quantified various induced cellular effects, in particular an increase of the levels of the enzyme glutathione S-transferase involved in cell detoxification. Our results highlight the importance to increase awareness on ECs pollution, promoting the use of more environmental friendly products to achieving the sustainable development goals.
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- 2023
47. Occurrence, sources, and ecological risks of polycyclic aromatic hydrocarbons (PAHs) in the Amazon river
- Author
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Rizzi, C, Villa, S, Waichman, A, de Souza Nunes, G, de Oliveira, R, Vighi, M, Rico, A, Waichman, AV, Rico A, Rizzi, C, Villa, S, Waichman, A, de Souza Nunes, G, de Oliveira, R, Vighi, M, Rico, A, Waichman, AV, and Rico A
- Abstract
The Amazon is the largest river by discharge volume and one of the most biodiverse biomes in the world. Lately, there has been a rapid increase of the urban population in the region, which has been translated into a growing emission of organic contaminants such as polycyclic aromatic hydrocarbons (PAHs) into surface water bodies. This study provides the most comprehensive evaluation of the PAH contamination levels in surface waters of the Amazon basin. We investigated the occurrence and potential sources of 16 priority PAHs and characterised their risks for freshwater ecosystems. For this, we took 40 water samples from different sites along the Brazilian part of the Amazon River, including three major tributaries, and smaller rivers crossing the main urban areas. The results of this study show that PAHs are widespread contaminants in rivers of the Brazilian Amazon. The sum of the total concentration of the 16 priority PAHs reached values of 134 ng L−1 in the Amazon River, and 163 ng L−1 near densely populated areas. On the other hand, the total PAH concentration was generally lower in the monitored tributaries. In most samples, the contamination pattern was dominated by high molecular weight PAHs, suggesting a major contribution of pyrogenic sources, although petrogenic contamination was also present in some locations near urban areas. We assessed ecological risks posed by PAH mixtures using a hazard index. The results indicated that PAH contamination is not likely to pose direct toxic effects for Amazonian freshwater organisms, however continued monitoring is recommended near densely populated areas.
- Published
- 2023
48. Five-year experience of tele-ophthalmology for diabetic retinopathy screening in a rural population
- Author
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Rodríguez Villa, S., Alonso Álvarez, C., de Dios del Valle, R., Salazar Méndez, R., Cuesta García, M., Ruiz García, M.J., Cubillas Martín, M., and Rodríguez Vazquez, M.
- Published
- 2016
- Full Text
- View/download PDF
49. Análisis de un programa de teleoftalmología para el cribado de retinopatía diabética en área rural tras cinco años
- Author
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Rodríguez Villa, S., Alonso Álvarez, C., de Dios del Valle, R., Salazar Méndez, R., Cuesta García, M., Ruiz García, M.J., Cubillas Martín, M., and Rodríguez Vazquez, M.
- Published
- 2016
- Full Text
- View/download PDF
50. Usefulness of surgical complexity classification index in cataract surgery process
- Author
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Salazar Méndez, R., Cuesta García, M., Llaneza Velasco, M.E., Rodríguez Villa, S., Cubillas Martín, M., and Alonso Álvarez, C.M.
- Published
- 2016
- Full Text
- View/download PDF
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