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8. Las Tic en educación superior : Experiencias de innovación

Author

Barreto, Carmen Ricardo, Díazgranados, Fernando Iriarte, Hung, Elías Said, Cantillo, Blessed Ballesteros, Molinares, Daladier Jabba, Salcedo, Edna Manotas, Álvarez, Daniel Salas, Cárdenas, Andrés Peláez, Agudelo, Verónica Villa, Álvarez, Sergio Zapata, Gonzálvez, Marlin Aarón, Almazo, Hilda Choles, Villa, Mónica Ordoñez, Castilla, Eliana Vergara, Jiménez, Andrés Chavarro, Acevedo, Cinthia Astorga, Barreto, Carmen Ricardo, Díazgranados, Fernando Iriarte, Hung, Elías Said, Cantillo, Blessed Ballesteros, Molinares, Daladier Jabba, Salcedo, Edna Manotas, Álvarez, Daniel Salas, Cárdenas, Andrés Peláez, Agudelo, Verónica Villa, Álvarez, Sergio Zapata, Gonzálvez, Marlin Aarón, Almazo, Hilda Choles, Villa, Mónica Ordoñez, Castilla, Eliana Vergara, Jiménez, Andrés Chavarro, and Acevedo, Cinthia Astorga

Published
2017
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10. A Culturally Adapted Intervention for Mexican‐Origin Parents of Adolescents: The Need to Overtly Address Culture and Discrimination in Evidence‐Based Practice

Author

Parra‐Cardona, Rubén, primary, López‐Zerón, Gabriela, additional, Leija, Silvia Gisela, additional, Maas, Megan K., additional, Villa, Monica, additional, Zamudio, Efraín, additional, Arredondo, Melecia, additional, Yeh, Hsueh‐Han, additional, and Domenech Rodríguez, Melanie M., additional

Published
2018
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12. Autophagy protects against neural cell death induced by piperidine alkaloids present in Prosopis juliflora (Mesquite)

Author

SILVA, VICTOR D.A., primary, CUEVAS, CARLOS, additional, MUÑOZ, PATRICIA, additional, VILLA, MONICA, additional, AHUMADA-CASTRO, ULISES, additional, HUENCHUGUALA, SANDRO, additional, SANTOS, CLEONICE C. DOS, additional, ARAUJO, FILLIPE M. DE, additional, FERREIRA, RAFAEL S, additional, SILVA, VANESSA B. DA, additional, SILVA, JULIANA H.C. E, additional, SOARES, ÉRICA N., additional, VELOZO, EUDES S., additional, SEGURA-AGUILAR, JUAN, additional, and COSTA, SILVIA L., additional

Published
2017
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13. A Culturally Adapted Intervention for Mexican‐Origin Parents of Adolescents: The Need to Overtly Address Culture and Discrimination in Evidence‐Based Practice.

Author

Parra‐Cardona, Rubén, López‐Zerón, Gabriela, Leija, Silvia Gisela, Maas, Megan K., Villa, Monica, Zamudio, Efraín, Arredondo, Melecia, Yeh, Hsueh‐Han, and Domenech Rodríguez, Melanie M.

Subjects
EDUCATION of Hispanic Americans, EDUCATION of immigrants, ADAPTABILITY (Personality), DISCRIMINATION (Sociology), CULTURAL pluralism, SELF-evaluation, EVIDENCE-based medicine, QUALITATIVE research, PROFESSIONAL practice, EMPIRICAL research, HUMAN services programs, PARENTING education, FAMILY attitudes
Abstract

Copyright of Family Process is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019
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15. Glutathione transferase mu 2 protects glioblastoma cells against aminochrome toxicity by preventing autophagy and lysosome dysfunction

Author

Huenchuguala, Sandro, Munoz, Patricia, Zavala, Patricio, Villa, Monica, Cuevas, Carlos, Ahumada, Ulises, Graumann, Rebecca, Nore, Beston F., Couve, Eduardo, Mannervik, Bengt, Paris, Irmgard, Segura-Aguilar, Juan, Huenchuguala, Sandro, Munoz, Patricia, Zavala, Patricio, Villa, Monica, Cuevas, Carlos, Ahumada, Ulises, Graumann, Rebecca, Nore, Beston F., Couve, Eduardo, Mannervik, Bengt, Paris, Irmgard, and Segura-Aguilar, Juan

Abstract

U373MG cells constitutively express glutathione S-transferase mu 2 (GSTM2) and exhibit H-3-dopamine uptake, which is inhibited by 2 mu M of nomifensine and 15 mu M of estradiol. We generated a stable cell line (U373MGsiGST6) expressing an siRNA against GSTM2 that resulted in low GSTM2 expression (26% of wild-type U373MG cells). A significant increase in cell death was observed when U373MGsiGST6 cells were incubated with 50 mu M purified aminochrome (18-fold increase) compared with wild-type cells. The incubation of U373MGsiGST6 cells with 75 mu M aminochrome resulted in the formation of autophagic vacuoles containing undigested cellular components, as determined using transmission electron microscopy. A significant increase in autophagosomes was determined by measuring endogenous LC3-II, a significant decrease in cell death was observed in the presence of bafilomycin A(1), and a significant increase in cell death was observed in the presence of trehalose. A significant increase in LAMP2 immunostaining was observed, a significant decrease in bright red fluorescence of lysosomes with acridine orange was observed, and bafilomycin A(1) pretreatment reduced the loss of lysosome acidity. A significant increase in cell death was observed in the presence of lysosomal protease inhibitors. Aggregation of TUBA/-tubulin (tubulin, ) and SQSTM1 protein accumulation were also observed. Moreover, a significant increase in the number of lipids droplets was observed compared with U373MG cells with normal expression of GSTM2. These results support the notion that GSTM2 is a protective enzyme against aminochrome toxicity in astrocytes and that aminochrome cell death in U373MGsiGST6 cells involves autophagic-lysosomal dysfunction., AuthorCount:12

Published
2014
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17. The synthesis of novel conducting polymers and oligomers for use in electrical devices, drug delivery systems, and energy dynamics studies

Author

Villa, Monica Irais, 1982-

Subjects
Conducting polymers, F8BT, Polythiophene, Oligothiophene, Nitric oxide, Fluorene, Oligomer, Solid phase synthesis, Electrochemistry, Electropolymerization
Abstract

Described herein are three projects centered on the synthesis of conducting polymer derivatives for various applications. The first is the novel synthesis of 9,9-dioctylfluorene-co-benzothiadiazole [F8BT] oligomers through solid phase synthesis for the study of the thermodynamics and kinetics of electron transfer in the polymer. The second endeavor involves the synthesis of a series of 4”,3’’’-dialkyl-2,2’:5’,2”:5”,2’’’:5’’’,2’’’’:5’’’’,2’’’’’-sexithiophenes for the studies on crystal packing and surface deposition of organic p-type semiconducting materials. Lastly is described the development of a conducting metallopolymer based on the ligand 2,6-Bis(4-(2,2’-bithiophen-5-yl)-1H-pyrazol-1-yl)pyridine for use in a drug delivery system.

Published
2010

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