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2. Effects of an L-Leucine-Rich Diet on Liver and Kidneys in a Doxorubicin Toxicity Model

Author

Duarte, Poliana Rodrigues Alves, primary, Franco, Rodrigo Rodrigues, additional, Vilela, Danielle Diniz, additional, Caixeta, Douglas Carvalho, additional, de Souza, Adriele Vieira, additional, Deconte, Simone Ramos, additional, Mendes-Rodrigues, Clesnan, additional, Fidale, Thiago Montes, additional, Espindola, Foued Salmen, additional, Teixeira, Renata Roland, additional, and Resende, Elmiro Santos, additional

Published
2023
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4. Increased selenium concentration in the synthesis of CdSe magic‐sized quantum dots affects how the brain responds to oxidative stress

Author

Vilela, Danielle Diniz, primary, Justino, Allisson Benatti, additional, Caixeta, Douglas Carvalho, additional, de Souza, Adriele Vieira, additional, Teixeira, Renata Roland, additional, Franco, Rodrigo Rodrigues, additional, Saraiva, André Lopes, additional, Fonseca, Belchiolina Beatriz, additional, Dantas, Noelio Oliveira, additional, Silva, Anielle Christine Almeida, additional, and Espindola, Foued Salmen, additional

Published
2021
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5. Increased selenium concentration in the synthesis of CdSe magic‐sized quantum dots affects how the brain responds to oxidative stress.

Author

Vilela, Danielle Diniz, Justino, Allisson Benatti, Caixeta, Douglas Carvalho, de Souza, Adriele Vieira, Teixeira, Renata Roland, Franco, Rodrigo Rodrigues, Saraiva, André Lopes, Fonseca, Belchiolina Beatriz, Dantas, Noelio Oliveira, Silva, Anielle Christine Almeida, and Espindola, Foued Salmen

Subjects
QUANTUM dots, OXIDATIVE stress, OXIDANT status, BIOLUMINESCENCE, SELENIUM, CATALASE, REDUCTASES
Abstract

CdSe magic‐sized quantum dots (MSQDs) have been widely used as fluorescent probes in biological systems due to their excellent optical properties with a broader fluorescence spectrum and stable luminescence in biological media. However, they can be cytotoxic and alter the redox balance depending on the amounts of Cd2+ adsorbed on their surface. Thus, the present study aimed to evaluate whether increases in selenium concentration in the synthesis of CdSe‐MSQDs decrease the oxidative stress caused by Cd2+‐based quantum dots. CdSe‐MSQDs synthesized with different concentrations of selenium were investigated against oxidative stress in the brain of chicken embryos by examining total antioxidant capacity, lipid peroxidation, thiol, and glutathione contents, as well as the activities of glutathione peroxidase, superoxide dismutase (SOD), catalase (CAT), and glutathione reductase. In addition, the vascularization of the chorioallantoic membrane (CAM) analysis was performed. Higher selenium concentrations alter the surface defect levels (decrease free Cd2+) and controlled the oxidative effects of CdSe‐MSQDs by reducing the lipid peroxidation, restoring the glutathione defense system and the antioxidant enzymes SOD and CAT, and maintaining the vascular density of the CAM. The current findings reinforce the study of the effects of the presence of Cd2+ ions on the surface of quantum dots, changing toxicity, and aiming interesting strategies of nanomaterials in biological systems. [ABSTRACT FROM AUTHOR]

Published
2022
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6. Effects of salbutamol and phlorizin on acute pulmonary inflammation and disease severity in experimental sepsis

Author

Cardoso-Sousa, Léia, primary, Aguiar, Emilia Maria Gomes, additional, Caixeta, Douglas Carvalho, additional, Vilela, Danielle Diniz, additional, Costa, Danilo Pereira da, additional, Silva, Tamires Lopes, additional, Cunha, Thúlio Marquez, additional, Faria, Paulo Rogério, additional, Espindola, Foued Salmen, additional, Jardim, Ana Carolina, additional, Vieira, Alexandre Antônio, additional, Oliveira, Tales Lyra, additional, Goulart, Luiz Ricardo, additional, and Sabino-Silva, Robinson, additional

Published
2019
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8. Royal jelly decreases corticosterone levels and improves the brain antioxidant system in restraint and cold stressed rats

Author

Teixeira, Renata Roland, primary, de Souza, Adriele Vieira, additional, Peixoto, Leonardo Gomes, additional, Machado, Helen Lara, additional, Caixeta, Douglas Carvalho, additional, Vilela, Danielle Diniz, additional, Baptista, Nathalia Belele, additional, Franci, Celso Rodrigues, additional, and Espindola, Foued Salmen, additional

Published
2017
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9. Hepatoprotective Properties of a Polyphenol-Enriched Fraction from Annona crassiflora Mart. Fruit Peel against Diabetes-Induced Oxidative and Nitrosative Stress

Author

Justino, Allisson Benatti, primary, Pereira, Mariana Nunes, additional, Peixoto, Leonardo Gomes, additional, Vilela, Danielle Diniz, additional, Caixeta, Douglas Carvalho, additional, de Souza, Adriele Vieira, additional, Teixeira, Renata Roland, additional, Silva, Heitor Cappato Guerra, additional, de Moura, Francyelle Borges Rosa, additional, Moraes, Izabela Barbosa, additional, and Espindola, Foued Salmen, additional

Published
2017
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10. Stephalagine, an alkaloid with pancreatic lipase inhibitory activity isolated from the fruit peel of Annona crassiflora Mart.

Author

Pereira, Mariana Nunes, primary, Justino, Allisson Benatti, additional, Martins, Mário Machado, additional, Peixoto, Leonardo Gomes, additional, Vilela, Danielle Diniz, additional, Santos, Paula Souza, additional, Teixeira, Thaise Lara, additional, da Silva, Cláudio Vieira, additional, Goulart, Luiz Ricardo, additional, Pivatto, Marcos, additional, and Espindola, Foued Salmen, additional

Published
2017
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