379 results on '"Vilagut, G."'
Search Results
2. Loneliness trajectories, risk factors, and mental health during the COVID-19 pandemic in Spain
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Gabarrell-Pascuet, A, primary, Domènech-Abella, J, additional, Mortier, P, additional, Felez-Nobrega, M, additional, Cristóbal-Narváez, P, additional, Vilagut, G, additional, Olaya, B, additional, Alonso, J, additional, and Haro, J M, additional
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- 2023
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3. Population norms for the EQ-5D-3L: a cross-country analysis of population surveys for 20 countries
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Janssen, M. F., Szende, A., Cabases, J., Ramos-Goñi, J. M., Vilagut, G., and König, H. H.
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- 2019
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4. Corrigendum to ‘Suicide-related thoughts and behavior and suicide death trends during the COVID-19 in the general population of Catalonia, Spain’ [European Neuropsychopharmacology 56 (2021) 4–12]
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Pérez, V., primary, Elices, M., additional, Vilagut, G., additional, Vieta, E., additional, Blanch, J., additional, Laborda-Serrano, E., additional, Prat, B., additional, Colom, F., additional, Palao, D., additional, and Alonso, J., additional
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- 2023
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5. Testing the PROMIS® Depression measures for monitoring depression in a clinical sample outside the US
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Vilagut, G., Forero, C.G., Adroher, N.D., Olariu, E., Cella, D., and Alonso, J.
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- 2015
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6. Gender differences in psychotropic use across Europe: Results from a large cross-sectional, population-based study
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Boyd, A., Van de Velde, S., Pivette, M., ten Have, M., Florescu, S., O’Neill, S., Caldas-de-Almeida, J.-M., Vilagut, G., Haro, J.M., Alonso, J., and Kovess-Masféty, V.
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- 2015
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7. Suicidality and its relationship with depression, alcohol disorders and childhood experiences of violence: Results from the ESEMeD study
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Hardt, J., Bernert, S., Matschinger, H., Angermeier, M.C., Vilagut, G., Bruffaerts, R., de Girolamo, G., de Graaf, R., Haro, J.M., Kovess, V., and Alonso, J.
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- 2015
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8. Prevalence of depression in Europe using two different PHQ-8 scoring methods
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Arias De La Torre, J., primary, Vilagut, G., additional, Ronaldson, A., additional, Serrano-Blanco, A., additional, Valderas, J., additional, Martín, V., additional, Dregan, A., additional, Bakolis, I., additional, and Alonso, J., additional
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- 2022
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9. Four-month incidence of suicidal thoughts and behaviors among healthcare workers after the first wave of the Spain COVID-19 pandemic
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Mortier, P., primary, Vilagut, G., additional, Alayo, I., additional, Ferrer, M., additional, Amigo, F., additional, Aragonès, E., additional, Aragón-Peña, A., additional, Asúnsolo del Barco, A., additional, Campos, M., additional, Espuga, M., additional, González-Pinto, A., additional, Haro, J.M., additional, López Fresneña, N., additional, Martínez de Salázar, A., additional, Molina, J.D., additional, Ortí-Lucas, R.M., additional, Parellada, M., additional, Pelayo-Terán, J.M., additional, Pérez-Gómez, B., additional, Pérez-Zapata, A., additional, Pijoan, J.I., additional, Plana, N., additional, Polentinos-Castro, E., additional, Portillo-Van Diest, A., additional, Puig, M.T., additional, Rius, C., additional, Sanz, F., additional, Serra, C., additional, Urreta-Barallobre, I., additional, Kessler, R.C., additional, Bruffaerts, R., additional, Vieta, E., additional, Pérez-Solá, V., additional, Alonso, J., additional, Alonso, Jordi, additional, Alayo, Itxaso, additional, Alonso, Manuel, additional, Álvarez, Mar, additional, Amann, Benedikt, additional, Amigo, Franco F., additional, Anmella, Gerard, additional, Aragón, Andres, additional, Aragonés, Nuria, additional, Aragonès, Enric, additional, Arizón, Ana Isabel, additional, Asunsolo, Angel, additional, Ayora, Alfons, additional, Ballester, Laura, additional, Barbas, Puri, additional, Basora, Josep, additional, Bereciartua, Elena, additional, Ignasi Bolibar, Inés Bravo, additional, Bonfill, Xavier, additional, Cotillas, Alberto, additional, Cuartero, Andres, additional, de Paz, Concha, additional, Cura, Isabel del, additional, Jesus del Yerro, Maria, additional, Diaz, Domingo, additional, Domingo, Jose Luis, additional, Emparanza, Jose I., additional, Espallargues, Mireia, additional, Espuga, Meritxell, additional, Estevan, Patricia, additional, Fernandez, M. Isabel, additional, Fernandez, Tania, additional, Ferrer, Montse, additional, Ferreres, Yolanda, additional, Fico, Giovanna, additional, Forjaz, M. Joao, additional, Barranco, Rosa Garcia, additional, Garcia TorrecillasC Garcia-Ribera, J. Manuel, additional, Garrido, Araceli, additional, Gil, Elisa, additional, Gomez, Marta, additional, Gomez, Javier, additional, Pinto, Ana Gonzalez, additional, Haro, Josep Maria, additional, Hernando, Margarita, additional, Insigna, Maria Giola, additional, Iriberri, Milagros, additional, Jimenez, Nuria, additional, Jimenez, Xavi, additional, Larrauri, Amparo, additional, Leon, Fernando, additional, Lopez-Fresneña, Nieves, additional, Lopez, Carmen, additional, Lopez-Atanes Juan Antonio Lopez-Rodriguez, Mayte, additional, Lopez-Cortacans, German, additional, Marcos, Alba, additional, Martin, Jesus, additional, Martin, Vicente, additional, Martinez-Cortés, Mercedes, additional, Martinez-Martinez, Raquel, additional, Martinez de Salazar, Alma D., additional, Martinez, Isabel, additional, Marzola, Marco, additional, Mata, Nelva, additional, Molina, Josep Maria, additional, de Dios Molina, Juan, additional, Molinero, Emilia, additional, Mortier, Philippe, additional, Muñoz, Carmen, additional, Murru, Andrea, additional, Olmedo, Jorge, additional, Ortí, Rafael M., additional, Padrós, Rafael, additional, Pallejà, Meritxell, additional, Parra, Raul, additional, Pascual, Julio, additional, Pelayo, Jose Maria, additional, Pla, Rosa, additional, Plana, Nieves, additional, Aznar, Coro Perez, additional, Gomez, Beatriz Perez, additional, Zapata, Aurora Perez, additional, Pijoan, Jose Ignacio, additional, Polentinos, Elena, additional, Puertolas, Beatriz, additional, Puig, Maria Teresa, additional, Quílez, Alex, additional, Quintana, M. Jesus, additional, Quiroga, Antonio, additional, Rentero, David, additional, Rey, Cristina, additional, Rius, Cristina, additional, Rodriguez-Blazquez, Carmen, additional, Rojas, M. Jose, additional, Romero, Yamina, additional, Rubio, Gabriel, additional, Rumayor, Mercedes, additional, Ruiz, Pedro, additional, Saenz, Margarita, additional, Sanchez, Jesus, additional, Sanchez-Arcilla, Ignacio, additional, Sanz, Ferran, additional, Serra, Consol, additional, Serra-Sutton, Victoria, additional, Serrano, Manuela, additional, Sola, Silvia, additional, Solera, Sara, additional, Soto, Miguel, additional, Tarrago, Alejandra, additional, Tolosa, Natividad, additional, Vazquez, Mireia, additional, Viciola, Margarita, additional, Vieta, Eduard, additional, Vilagut, Gemma, additional, Yago, Sara, additional, Yañez, Jesus, additional, Zapico, Yolanda, additional, Zorita, Luis Maria, additional, Zorrilla, Iñaki, additional, Zurbano, Saioa L., additional, and Perez-Solá, Victor, additional
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- 2022
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10. Four-month incidence of suicidal thoughts and behaviors among healthcare workers after the first wave of the Spain COVID-19 pandemic
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Alonso, Jordi, Alayo, Itxaso, Alonso, Manuel, Álvarez, Mar, Amann, Benedikt, Amigo, Franco F., Anmella, Gerard, Aragón, Andres, Aragonés, Nuria, Aragonès, Enric, Arizón, Ana Isabel, Asunsolo, Angel, Ayora, Alfons, Ballester, Laura, Barbas, Puri, Basora, Josep, Bereciartua, Elena, Ignasi Bolibar, Inés Bravo, Bonfill, Xavier, Cotillas, Alberto, Cuartero, Andres, de Paz, Concha, Cura, Isabel del, Jesus del Yerro, Maria, Diaz, Domingo, Domingo, Jose Luis, Emparanza, Jose I., Espallargues, Mireia, Espuga, Meritxell, Estevan, Patricia, Fernandez, M. Isabel, Fernandez, Tania, Ferrer, Montse, Ferreres, Yolanda, Fico, Giovanna, Forjaz, M. Joao, Barranco, Rosa Garcia, Garcia TorrecillasC Garcia-Ribera, J. Manuel, Garrido, Araceli, Gil, Elisa, Gomez, Marta, Gomez, Javier, Pinto, Ana Gonzalez, Haro, Josep Maria, Hernando, Margarita, Insigna, Maria Giola, Iriberri, Milagros, Jimenez, Nuria, Jimenez, Xavi, Larrauri, Amparo, Leon, Fernando, Lopez-Fresneña, Nieves, Lopez, Carmen, Lopez-Atanes Juan Antonio Lopez-Rodriguez, Mayte, Lopez-Cortacans, German, Marcos, Alba, Martin, Jesus, Martin, Vicente, Martinez-Cortés, Mercedes, Martinez-Martinez, Raquel, Martinez de Salazar, Alma D., Martinez, Isabel, Marzola, Marco, Mata, Nelva, Molina, Josep Maria, de Dios Molina, Juan, Molinero, Emilia, Mortier, Philippe, Muñoz, Carmen, Murru, Andrea, Olmedo, Jorge, Ortí, Rafael M., Padrós, Rafael, Pallejà, Meritxell, Parra, Raul, Pascual, Julio, Pelayo, Jose Maria, Pla, Rosa, Plana, Nieves, Aznar, Coro Perez, Gomez, Beatriz Perez, Zapata, Aurora Perez, Pijoan, Jose Ignacio, Polentinos, Elena, Puertolas, Beatriz, Puig, Maria Teresa, Quílez, Alex, Quintana, M. Jesus, Quiroga, Antonio, Rentero, David, Rey, Cristina, Rius, Cristina, Rodriguez-Blazquez, Carmen, Rojas, M. Jose, Romero, Yamina, Rubio, Gabriel, Rumayor, Mercedes, Ruiz, Pedro, Saenz, Margarita, Sanchez, Jesus, Sanchez-Arcilla, Ignacio, Sanz, Ferran, Serra, Consol, Serra-Sutton, Victoria, Serrano, Manuela, Sola, Silvia, Solera, Sara, Soto, Miguel, Tarrago, Alejandra, Tolosa, Natividad, Vazquez, Mireia, Viciola, Margarita, Vieta, Eduard, Vilagut, Gemma, Yago, Sara, Yañez, Jesus, Zapico, Yolanda, Zorita, Luis Maria, Zorrilla, Iñaki, Zurbano, Saioa L., Perez-Solá, Victor, Mortier, P., Vilagut, G., Alayo, I., Ferrer, M., Amigo, F., Aragonès, E., Aragón-Peña, A., Asúnsolo del Barco, A., Campos, M., Espuga, M., González-Pinto, A., Haro, J.M., López Fresneña, N., Martínez de Salázar, A., Molina, J.D., Ortí-Lucas, R.M., Parellada, M., Pelayo-Terán, J.M., Pérez-Gómez, B., Pérez-Zapata, A., Pijoan, J.I., Plana, N., Polentinos-Castro, E., Portillo-Van Diest, A., Puig, M.T., Rius, C., Sanz, F., Serra, C., Urreta-Barallobre, I., Kessler, R.C., Bruffaerts, R., Vieta, E., Pérez-Solá, V., and Alonso, J.
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- 2022
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11. Type of pre-existing mental disorder determines changes and levels of anxiety and depressive symptoms during the COVID-19 pandemic
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Monistrol-Mula, A., Félez-Nobrega, M., Moneta, M.V., Condominas, E., Vilagut, G., Domènech-Abella, J., Philippe, M., Cristóbal-Narváez, P., Olaya, B., Alonso, J., and Haro, J.M.
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- 2022
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12. Prevalence and correlates of respiratory and non-respiratory panic attacks in the general population
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Fullana, M.A., Vilagut, G., Ortega, N., Bruffaerts, R., de Girolamo, G., de Graaf, R., Haro, J.M., Kovess, V., Matschinger, H., Bulbena, A., and Alonso, J.
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- 2011
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13. Prevalence of Major Depressive Episode in 27 European Countries
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Arias de la Torre, J, primary, Ronaldson, A, additional, Vilagut, G, additional, Peters, M, additional, Valderas, JM, additional, Serrano-Blanco, A, additional, Martín, V, additional, Dregan, A, additional, and Alonso, J, additional
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- 2021
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14. Obsessive–compulsive symptom dimensions in the general population: Results from an epidemiological study in six European countries
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Fullana, M.A., Vilagut, G., Rojas-Farreras, S., Mataix-Cols, D., de Graaf, R., Demyttenaere, K., Haro, J.M., de Girolamo, G., Lépine, J.P., Matschinger, H., and Alonso, J.
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- 2010
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15. The association of detachment with affective disorder symptoms during the COVID-19 lockdown: The role of living situation and social support
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Joan Domènech Abella, Gabarrell-Pascuet A, Faris LH, Cristóbal-Narváez P, Félez-Nobrega M, Mortier P, Vilagut G, Olaya B, Alonso J, and Haro JM
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Social networks ,Anxiety ,Lockdown ,Depression ,Detachment - Abstract
INTRODUCTION: There is growing concern about the effect of lockdown and social distancing on mental health. Subjective feelings related to social relationships such as detachment have shown a strong effect on mental health, whereas objective factors might have a moderating role in that association. OBJECTIVE: To investigate whether social support and living situation have a moderating effect on the association between detachment and affective disorder symptoms during the COVID-19 lockdown. METHODS: 3,305 Spanish adults were interviewed by phone at the end of the COVID-19 lockdown (May-June 2020). Detachment during confinement was assessed with a single-item frequency question. Anxiety symptoms were measured through GAD-7, depressive symptoms through PHQ-9, and social support through the Oslo Social Support Scale (OSSS). Associations with anxiety and depressive symptoms were tested through Tobit regression models. Interactions of detachment with living situation and social support were tested as independent variables. RESULTS: People living alone showed significantly lower levels of anxiety whereas people living with another (but not as a couple) showed higher levels of depression. Detachment was strongly associated with both affective disorders. Social support had a statistically significant moderating effect on that association. Those with a low level of social support and a high level of detachment reported means of depression and anxiety above major depression (10.5 CI 95% 9.6, 11.4 at OSSS=10) and generalized anxiety disorders (10.1 CI 95% 9.2, 11.0 at OSSS=9) cut offs CONCLUSION: Interventions centered on improving social support could alleviate feelings of detachment and prevent affective disorders during lockdowns.
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- 2021
16. Validation of an Online Version of the Alcohol Use Disorders Identification Test (AUDIT) for Alcohol Screening in Spanish University Students
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Ballester L, Alayo I, Vilagut G, Almenara J, Cebrià AI, Echeburúa E, Gabilondo A, Gili M, Lagares C, Piqueras JA, Roca M, Soto-Sanz V, Blasco MJ, Castellví P, G Forero C, Mortier P, and Alonso J
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validity ,Alcohol Use Disorders Identification Test (AUDIT) ,online survey ,university students - Abstract
Online alcohol screening may be helpful in preventing alcohol use disorders. We assessed psychometric properties of an online version of the Alcohol Use Disorders Identification Test (AUDIT) among Spanish university students. We used a longitudinal online survey (the UNIVERSAL project) of first-year students (18-24 years old) in five universities, including the AUDIT, as part of the WHO World Mental Health International College Student (WMH-ICS) initiative. A reappraisal interview was carried out with the Timeline Followback (TLFB) for alcohol consumption categories and the Mini International Neuropsychiatric Interview (MINI) for alcohol use disorder. Reliability, construct validity and diagnostic accuracy were assessed. Results: 287 students (75% women) completed the MINI, of whom 242 also completed the TLFB. AUDIT's Cronbach's alpha was 0.82. The confirmatory factor analysis for the one-factor solution of the AUDIT showed a good fit to the data. Significant AUDIT score differences were observed by TLFB categories and by MINI disorders. Areas under the curve (AUC) were very large for dependence (AUC = 0.96) and adequate for consumption categories (AUC > 0.7). AUDIT cut-off points of 6/8 (women/men) for moderate-risk drinking and 13 for alcohol dependence showed sensitivity/specificity of 76.2%/78.9% and 56%/97.5%, respectively. The online version of the AUDIT is useful for detecting alcohol consumption categories and alcohol dependence in Spanish university students.
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- 2021
17. Diagnostic promiscuity: the use of real-world data to study multimorbidity in mental health
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Arias de la Torre J, Ronaldson A, Valderas JM, Vilagut G, Serrano-Blanco A, Hatch SL, Alonso J, Hotopf M, and Dregan A
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electronic health records ,cohort studies ,real-world data ,mental health-related multimorbidity ,Multimorbidity - Abstract
Mental health-related multimorbidity can be considered as multimorbidity in the presence of a mental disorder. Some knowledge gaps on the study of mental health-related multimorbidity were identified. These knowledge gaps could be potentially addressed with real-world data.
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- 2021
18. Prevalence and age patterns of depression in the United Kingdom. A population-based study
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Arias de la Torre J, Vilagut G, Ronaldson A, Dregan A, Ricci-Cabello I, Hatch SL, Serrano-Blanco A, Valderas JM, Hotopf M, and Alonso J
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Survey studies ,Age ,Depression ,PHQ-8 ,Prevalence - Abstract
METHODS: A representative sample of the UK population (n=17,152) from the European Health Interview Survey of 2014 was included in the analyses. The Patient Health Questionnaire (PHQ-8) was used to assess the prevalence of depressive symptoms and of probable depressive disorder. Prevalence estimates (95%CI) were calculated. The association between prevalence and age was assessed using multivariable multinomial logistic and logistic regression models. All analyses were carried out for the total sample and stratified by sex. RESULTS: The prevalence of depressive symptoms ranged from 11.3% (10.6-11.9) for mild, to 3.3% (3.0-3.7) for severe symptoms. The prevalence of probable depressive disorder was 7.5% (95%CI: 7.0-8.0). A significantly higher prevalence of probable depressive disorder was found in those aged 45 to 59 years old compared with those aged 16 to 29. For the prevalence of severe depressive symptoms those age differences were even higher: 2.55 times higher (5.38 for men and 1.75 for women). LIMITATIONS: The cross-sectional design precludes stablishing the direction of the relationship between age and the prevalence. CONCLUSIONS: The prevalence and age patterns of depression in the UK were described. A peak in the prevalence was identified during middle adulthood. These results could serve as a reference for the monitoring of depression in the UK and the development of preventive strategies, particularly in the high-risk population groups identified.
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- 2021
19. The role of social support, detachment, and depressive and anxiety symptoms in suicidal thoughts and behaviours during the Covid-19 lockdown: Potential pathways
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Gabarrell-Pascuet A, Félez-Nóbrega M, Cristóbal-Narváez P, Mortier P, Vilagut G, Olaya B, Alonso J, Haro JM, and Joan Domènech Abella
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Social support ,Suicide ,Detachment ,Anxiety symptoms ,Depressive symptoms ,COVID-19 - Abstract
During the COVID-19 pandemic, anxiety and depressive symptoms, as well as problems related to social relationships, such as available social support and feelings of detachment from others, have worsened. These factors are strongly associated with suicidal thoughts and behaviours (STB). The effects of feelings of detachment on mental health and on STB have been scarcely studied, together with the relation that it may have with available social support. Therefore, the aim of the present study was to assess potential pathways connecting these conditions. A nationally representative sample of Spanish adults (N = 3305) was interviewed during the COVID-19 pandemic (June 2020). STB, social support, and depressive and anxiety symptoms were measured with the C-SSRS (modified version), OSSS-3, PHQ-8, and GAD-7 scales, respectively. Multivariable logistic regression models and mediation analyses were performed. Social support and some of its components (i.e., social network size and relations of reciprocity) were associated with lower odds of STB. Detachment significantly mediated (22% to 25%) these associations. Symptoms of emotional disorders significantly mediated the association between social support components (29% to 38%) - but not neighbourhood support - with STB, as well as the association between detachment and higher odds of STB (47% to 57%). In both cases, depressive symptoms were slightly stronger mediating factors when compared to anxiety symptoms. Our findings suggest that interventions aimed at lowering depressive and anxiety symptoms, and STB should provide social support and help tackle the feeling of detachment in a complementary way.
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- 2021
20. Improving suicide surveillance systems through the use of the Patient Health Questionnaire-9
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Arias de la Torre J, Ronaldson A, Vilagut G, Serrano-Blanco A, Molina AJ, Martín V, Valderas JM, Dutta R, Dregan A, and Alonso J
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Surveillance ,Suicide ,Health services research ,Patient health questionnaire - Abstract
Suicide is a major public health problem worldwide and continues to be one of the main causes of death. Implementing surveillance strategies for suicidal thoughts and behaviours would make it possible to identify individuals at high risk of ending their lives by suicide. While a universal screening would be controversial, the increasing use of the 9-item version of the Patient Health Questionnaire (PHQ-9) in different healthcare settings, such as primary care or hospital emergency departments, offers an opportunity for testing its performance for suicide surveillance. Beyond being a screening of depression, the PHQ-9 has shown merit as a marker of suicidal thinking, thoughts of self-harm, and suicide. Implementing systematic surveillance strategies for suicide in different healthcare settings including data from the PHQ-9 might be an effective way to improve case detection. This could help to enhance the identification of highest risk population groups and, consequently, to avoid potentially preventable suicides.
- Published
- 2021
21. Use of general practitioners versus mental health professionals in six European countries: the decisive role of the organization of mental health-care systems
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Dezetter, Anne, Briffault, X., Bruffaerts, R., De Graaf, R., Alonso, J., König, H. H., Haro, J. M., de Girolamo, G., Vilagut, G., and Kovess-Masféty, V.
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- 2013
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22. Are attitudes towards mental health help-seeking associated with service use? Results from the European Study of Epidemiology of Mental Disorders
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ten Have, M., de Graaf, R., Ormel, J., Vilagut, G., Kovess, V., Alonso, J., and the ESEMeD/MHEDEA 2000 Investigators
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- 2010
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23. Mood and anxiety disorders across the adult lifespan: a European perspective
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McDowell, R. D., Ryan, A., Bunting, B. P., OʼNeill, S. M., Alonso, J., Bruffaerts, R., de Graaf, R., Florescu, S., Vilagut, G., de Almeida, J. M. C., de Girolamo, G., Haro, J. M., Hinkov, H., Kovess-Masfety, V., Matschinger, H., and Tomov, T.
- Published
- 2014
24. Birth-sex cohort alcohol use transitions in the general population: the cross-sectional PEGASUS-Murcia project
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HUSKY, Mathilde M., BHARAT, C., Vilagut, G., SALMERON, D., Martinez, S., Navarro, C., Alonso, J., KESSLER, R. C., Navarro-Mateu, F., Bordeaux population health (BPH), and Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)
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Remission ,Cohort-use ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,Alcohol ,Dependence ,HEALTHY ,Abuse - Abstract
International audience; To examine the potential impact of prevalence of alcohol use in a birth-sex cohort on subsequent initiation and progression of alcohol use in the PEGASUS-Murcia project, a cross-sectional survey of a representative sample of non-institutionalized adults in Murcia (Spain). Data on lifetime history of alcohol use, DSM-IV use disorders, and remission were collected from 1,459 adults using face-to-face interviewers based on the Composite International Diagnostic Interview (CIDI 3.0). Life-table estimates based on survival functions for alcohol use age-of-onset and remission were used as time-varying predictors of subsequent individual-level alcohol use in discrete-time survival models. Nearly nine out of ten adults had a lifetime alcohol use history at time of interview. Of these lifetime users, 84.3% became regular users (>12 drinks a year) and 5.5-1.6% went on to meet criteria for DSM-IV alcohol abuse or dependence, respectively. By the age of 18, 70.9% of respondents had used alcohol, and one half (50.2%) had used regularly. Regular use sharply increased during early adulthood to reach 90.8% by age 22. Birth-sex cohort alcohol use was significantly and positively associated with increased odds of all subsequent transitions examined except for the transition from use to abuse. The findings highlight sensitive periods with rapid transitions to higher levels of alcohol use and emphasize the importance of cohort experiences in the full spectrum of stages of alcohol use. These results may contribute to predicting population-levels trends in alcohol-related problems in Spain.
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- 2020
25. Developing a new version of the SF-6D health state classification system from the SF-36v2: SF-6Dv2
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Brazier, J, Mulhern, B, Bjorner, JB, Gandek, B, Rowen, D, Alonso, J, Vilagut, G, Ware, J, Brazier, J, Mulhern, B, Bjorner, JB, Gandek, B, Rowen, D, Alonso, J, Vilagut, G, and Ware, J
- Abstract
Objective: The objective of this study was to develop the classification system for version of the SF-6D (SF-6Dv2) from the SF-36v2. SF-6Dv2 is an improved version of SF-6D, one of the most widely used generic measures of health for the calculation of quality-adjusted life years. Study Design and Setting: A 3-step process was undertaken to generate a new classification system: (1) factor analysis to establish dimensionality; (2) Rasch analysis to understand item performance; and (3) tests of differential item function. To evaluate robustness, Rasch analyses were performed in multiple subsets of 2 large cross-sectional datasets from recently discharged hospital patients and online patient samples. Results: On the basis of factor analysis, other psychometric evidence, cross-cultural considerations, and amenability to valuation, the 6-dimension classification used in SF-6D was maintained. SF-6Dv2 resulted in the following modifications to SF-6D: a simpler classification of physical function with clearer separation between levels; a more detailed 5-level description of role limitations; using negative wording to describe vitality; and using pain severity rather than pain interference. Conclusions: The SF-6Dv2 classification system describes more distinct levels of health than SF-6D, changes the descriptions used for a number of dimensions and provides clearer wording for health state valuation. The second stage of the study has developed a utility value set using discrete choice methods so that the measure can be used in health technology assessment. Further work should investigate the psychometric characteristics of the new instrument.
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- 2020
26. Health-related quality of life during the bereavement period of caregivers of a deceased elderly person
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Rebollo, P., Alonso, J., Ramon, I., Vilagut, G., Santed, R., and Pujol, R.
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- 2005
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27. The Spanish version of the Paediatric Asthma Quality of Life Questionnaire (PAQLQ): Metric characteristics and equivalence with the original version
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Tauler, E., Vilagut, G., Grau, G., González, A., Sánchez, E., Figueras, G., Vall, O., Ferrer, M., and Alonso, J.
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- 2001
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28. Mental impact of Covid-19 among Spanish healthcare workers. A large longitudinal survey.
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Alonso, J., Vilagut, G., Alayo, I., Ferrer, M., Amigo, F., Aragón-Peña, A., Aragonès, E., Campos, M., del Cura-González, I., Urreta, I., Espuga, M., González Pinto, A., Haro, J. M., López Fresneña, N., Martínez de Salázar, A., Molina, J. D., Ortí Lucas, R. M., Parellada, M., Pelayo-Terán, J. M., and Pérez Zapata, A.
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MEDICAL personnel ,COVID-19 pandemic ,ALCOHOLISM ,COVID-19 ,MENTAL illness ,LOGISTIC regression analysis - Abstract
Aims: Longitudinal data on the mental health impact of the coronavirus disease 2019 (Covid-19) pandemic in healthcare workers is limited. We estimated prevalence, incidence and persistence of probable mental disorders in a cohort of Spanish healthcare workers (Covid-19 waves 1 and 2) -and identified associated risk factors. Methods: 8996 healthcare workers evaluated on 5 May–7 September 2020 (baseline) were invited to a second web-based survey (October–December 2020). Major depressive disorder (PHQ-8 ≥ 10), generalised anxiety disorder (GAD-7 ≥ 10), panic attacks, post-traumatic stress disorder (PCL-5 ≥ 7), and alcohol use disorder (CAGE-AID ≥ 2) were assessed. Distal (pre-pandemic) and proximal (pandemic) risk factors were included. We estimated the incidence of probable mental disorders (among those without disorders at baseline) and persistence (among those with disorders at baseline). Logistic regression of individual-level [odds ratios (OR)] and population-level (population attributable risk proportions) associations were estimated, adjusting by all distal risk factors, health care centre and time of baseline interview. Results: 4809 healthcare workers participated at four months follow-up (cooperation rate = 65.7%; mean = 120 days s.d. = 22 days from baseline assessment). Follow-up prevalence of any disorder was 41.5%, (v. 45.4% at baseline, p < 0.001); incidence, 19.7% (s.e. = 1.6) and persistence, 67.7% (s.e. = 2.3). Proximal factors showing significant bivariate-adjusted associations with incidence included: work-related factors [prioritising Covid-19 patients (OR = 1.62)], stress factors [personal health-related stress (OR = 1.61)], interpersonal stress (OR = 1.53) and financial factors [significant income loss (OR = 1.37)]. Risk factors associated with persistence were largely similar. Conclusions: Our study indicates that the prevalence of probable mental disorders among Spanish healthcare workers during the second wave of the Covid-19 pandemic was similarly high to that after the first wave. This was in good part due to the persistence of mental disorders detected at the baseline, but with a relevant incidence of about 1 in 5 of HCWs without mental disorders during the first wave of the Covid-19 pandemic. Health-related factors, work-related factors and interpersonal stress are important risks of persistence of mental disorders and of incidence of mental disorders. Adequately addressing these factors might have prevented a considerable amount of mental health impact of the pandemic among this vulnerable population. Addressing health-related stress, work-related factors and interpersonal stress might reduce the prevalence of these disorders substantially. Study registration number: NCT04556565 [ABSTRACT FROM AUTHOR]
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- 2022
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29. Days out of role due to common physical and mental conditions: results from the WHO World Mental Health surveys
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Alonso, J, Petukhova, M, Vilagut, G, Chatterji, S, Heeringa, S, Üstün, TB, Alhamzawi, AO, Viana, MC, Angermeyer, M, Bromet, E, Bruffaerts, R, de Girolamo, G, Florescu, S, Gureje, O, Haro, JM, Hinkov, H, Hu, C-y, Karam, EG, Kovess, V, Levinson, D, Medina-Mora, ME, Nakamura, Y, Ormel, J, Posada-Villa, J, Sagar, R, Scott, KM, Tsang, A, Williams, DR, and Kessler, RC
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- 2011
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30. Including information about co-morbidity in estimates of disease burden: results from the World Health Organization World Mental Health Surveys
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Alonso, J., Vilagut, G., Chatterji, S., Heeringa, S., Schoenbaum, M., Üstün, T. Bedirhan, Rojas-Farreras, S., Angermeyer, M., Bromet, E., Bruffaerts, R., de Girolamo, G., Gureje, O., Haro, J. M., Karam, A. N., Kovess, V., Levinson, D., Liu, Z., Medina-Mora, M. E., Ormel, J., Posada-Villa, J., Uda, H., and Kessler, R. C.
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- 2011
31. Psychometric properties of the World Health Organization Disability Assessment Schedule used in the European Study of the Epidemiology of Mental Disorders
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BUIST-BOUWMAN, M. A., ORMEL, J., DE GRAAF, R., VILAGUT, G., ALONSO, J., VAN SONDEREN, E., and VOLLEBERGH, W. A. M.
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- 2008
32. Association of perceived stigma and mood and anxiety disorders: results from the World Mental Health Surveys
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Alonso, J., Buron, A., Bruffaerts, R., He, Y., Posada-Villa, J., Lepine, J-P., Angermeyer, M. C., Levinson, D., de Girolamo, G., Tachimori, H., Mneimneh, Z. N., Medina-Mora, M. E., Ormel, J., Scott, K. M., Gureje, O., Haro, J. M., Gluzman, S., Lee, S., Vilagut, G., Kessler, R. C., and Von Korff, M.
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- 2008
33. Modification of the risk of post-traumatic stress disorder (PTSD) by the 5-HTTLPR polymorphisms after Lorca's earthquakes (Murcia, Spain)
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Navarro-Mateu F, Escamez T, Quesada M, Alcaraz M, Vilagut G, Salmeron D, Huerta J, Chirlaque M, Navarro C, Kessler R, Alonso J, and Martinez S
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- 2019
34. Childhood adversities and 5-HTTLPR polymorphism as risk factors of substance use disorders: retrospective case-control study in Murcia (Spain)
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Navarro-Mateu F, Quesada M, Escamez T, Alcaraz M, de la Pena C, Salmeron D, Huerta J, Vilagut G, Chirlaque M, Navarro C, Husky M, Kessler R, Alonso J, and Martinez S
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- 2019
35. Assessing oral health-related quality of life in children and adolescents: a systematic review and standardized comparison of available instruments
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Zaror, C, Pardo, Y, Espinoza-Espinoza, G, Pont, A, Munoz-Millan, P, Martinez-Zapata, MJ, Vilagut, G, Forero, CG, Garin, O, Alonso, J, and Ferrer, M
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Quality of life ,Questionnaires ,Outcome assessment ,Oral health ,Psychometrics ,Child - Abstract
ObjectivesTo obtain a systematic and standardized evaluation of the current evidence on development process, metric properties, and administration issues of oral health-related quality of life instruments available for children and adolescents.Materials and methodsA systematic search until October 2016 was conducted in PubMed, Embase, Lilacs, SciELO, and Cochrane databases. Articles with information regarding the development process, metric properties, and administration issues of pediatric instruments measuring oral health-related quality of life were eligible for inclusion. Two researchers independently evaluated each instrument applying the Evaluating Measures of Patient-Reported Outcomes (EMPRO) tool. An overall and seven attribute-specific EMPRO scores were calculated (range 0-100, worst to best): measurement model, reliability, validity, responsiveness, interpretability, burden, and alternative forms.ResultsWe identified 18 instruments evaluated in 132 articles. From five instruments designed for preschoolers, the Early Childhood Oral Health Impact Scale (ECOHIS) obtained the highest overall EMPRO score (82.2). Of nine identified for schoolchildren and adolescents, the best rated instrument was the Child Perceptions Questionnaire 11-14 (82.1). Among the four instruments developed for any age, the Family Impact Scale (FIS) obtained the highest scores (80.3).ConclusionThe evidence supports the use of the ECOHIS for preschoolers, while the age is a key factor when choosing among the four recommended instruments for schoolchildren and adolescents. Instruments for specific conditions, symptoms, or treatments need further research on metric properties.Clinical relevanceOur results facilitate decision-making on the correct oral health-related quality of life instrument selection for any certain study purpose and population during the childhood and adolescence life cycle.
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- 2019
36. Population norms for the EQ-5D-3L: a cross-country analysis of population surveys for 20 countries
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Janssen, MF (Bas), Szende, A, Cabases, J, Ramos-Goñi, JM, Vilagut, G, Konig, HH, Janssen, MF (Bas), Szende, A, Cabases, J, Ramos-Goñi, JM, Vilagut, G, and Konig, HH
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- 2019
37. Lifetime and 12-month treatment for mental disorders and suicidal thoughts and behaviors among first year college students
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Bruffaerts, R., Mortier, P., Auerbach, R., Alonso, J., Hermosillo De la Torre, A., Cuijpers, P., Demyttenaere, K., Ebert, D., Green, J., Hasking, Penelope, Stein, D., Ennis, E., Nock, M., Pinder-Amaker, S., Sampson, N., Vilagut, G., Zaslavsky, A., Kessler, R., Bruffaerts, R., Mortier, P., Auerbach, R., Alonso, J., Hermosillo De la Torre, A., Cuijpers, P., Demyttenaere, K., Ebert, D., Green, J., Hasking, Penelope, Stein, D., Ennis, E., Nock, M., Pinder-Amaker, S., Sampson, N., Vilagut, G., Zaslavsky, A., and Kessler, R.
- Abstract
© 2019 John Wiley & Sons, Ltd. Objectives: Mental disorders and suicidal thoughts and behaviors (STB) are common and burdensome among college students. Although available evidence suggests that only a small proportion of the students with these conditions receive treatment, broad-based data on patterns of treatment are lacking. The aim of this study is to examine the receipt of mental health treatment among college students cross-nationally. Methods: Web-based self-report surveys were obtained from 13,984 first year students from 19 colleges in eight countries across the world as part of the World Health Organization's World Mental Health–International College Student Initiative. The survey assessed lifetime and 12-month common mental disorders/STB and treatment of these conditions. Results: Lifetime and 12-month treatment rates were very low, with estimates of 25.3–36.3% for mental disorders and 29.5–36.1% for STB. Treatment was positively associated with STB severity. However, even among severe cases, lifetime and 12-month treatment rates were never higher than 60.0% and 45.1%, respectively. Conclusions: High unmet need for treatment of mental disorders and STB exists among college students. In order to resolve the problem of high unmet need, a reallocation of resources may focus on innovative, low-threshold, inexpensive, and scalable interventions.
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- 2019
38. Change in functioning outcomes as a predictor of the course of depression: a 12-month longitudinal study
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Forero, CG, Olariu, E, Alvarez, P, Castro-Rodriguez, JI, Blasco, MJ, Vilagut, G, Perez, V, Alonso, J, Barbaglia, G., and INSAyD Investigators
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Questionnaire ,Functional disability ,WHODAS ,Early intervention ,Affective disorders - Abstract
Functioning is a necessary diagnostic criterion for depression, and thus routinely assessed in depressive patients. While it is highly informative of disorder severity, its change has not been tested for prognostic purposes. Our study aimed to analyze to what extent early functioning changes predict depression in the mid-term. Longitudinal study (four occasions: baseline, 1, 3, and 12 months) of 243 patients with depressive symptomatology at three different services (primary care, outpatients, and hospital). Functioning was assessed on the first three occasions using the Global Assessment of Functioning (GAF), the WHODAS-2.0, and a self-reported functioning (SRF) rating scale. Growth mixture modeling of initial assessments served to estimate individual person-change parameters of each outcome. Person-growth parameters were used as predictors of major depressive episode at 12 months in a logistic regression model, adjusted by sex, age, healthcare level, and depression clinical status at third month. Predictive accuracy of all measures was assessed with area under the receiver operating curve (AUC). Of the 179 patients who completed all assessments, 58% had an active depression episode at baseline and 20% at 12 months (64% non-recoveries and 36% new onsets). Individual trends of change in functioning significantly predicted patient depression status a year later (AUC(WHODAS) = 0.76; AUC(GAF) = 0.92; AUC(SRF) = 0.93). Longitudinal modeling of functioning was highly predictive of patients' clinical status after 1 year. Although clinical and patient-reported assessment had high prognostic value, the use of very simple patient-reported outcome measures could improve case management outside specialized psychiatric services.
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- 2018
39. PRM206 - THE PERIODIC SYSTEMATIC REVIEW FOR BIBLIOPRO: A DECADE OF SPANISH PATIENT-REPORTED OUTCOMES.
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Pardo, Y, primary, Oriol Zerbe, C, additional, Garin, O, additional, Vilagut, G, additional, García-Forero, C., additional, Martí-Pastor, M., additional, Alayo, I, additional, Zamora, V, additional, Ferrer Fores, M, additional, Alonso, J, additional, and Empro, G, additional
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- 2018
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40. PRM217 - THE ONLINE VERSION OF EMPRO: A NEW PLATFORM SYSTEM FOR THE STANDARDIZED APPRAISAL OF PRO INSTRUMENTS.
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Garin, O, primary, García-Forero, C., additional, Vilagut, G, additional, Pardo, Y, additional, Alayo, I, additional, Oriol Zerbe, C, additional, Valderas, JM, additional, Alonso, J, additional, Ferrer Fores, M, additional, and Empro, G, additional
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- 2018
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41. Thirty-day suicidal thoughts and behaviours in the Spanish adult general population during the first wave of the Spain COVID-19 pandemic.
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Mortier, P., Vilagut, G., Ferrer, M., Alayo, I., Bruffaerts, R., Cristóbal-Narváez, P., del Cura-González, I., Domènech-Abella, J., Felez-Nobrega, M., Olaya, B., Pijoan, J. I., Vieta, E., Pérez-Solà, V., Kessler, R. C., Haro, J. M., Alonso, J., Saioa L., Alayo, Itxaso, Alonso, Jordi, and Alonso, Manuel
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COVID-19 ,COVID-19 pandemic ,SUICIDAL ideation ,SPANIARDS ,SUBSTANCE abuse ,MENTAL illness - Abstract
Aims: To investigate the prevalence of suicidal thoughts and behaviours (STB; i.e. suicidal ideation, plans or attempts) in the Spanish adult general population during the first wave of the Spain coronavirus disease 2019 (COVID-19) pandemic (March−July, 2020), and to investigate the individual- and population-level impact of relevant distal and proximal STB risk factor domains. Methods: Cross-sectional study design using data from the baseline assessment of an observational cohort study (MIND/COVID project). A nationally representative sample of 3500 non-institutionalised Spanish adults (51.5% female; mean age = 49.6 [s.d. = 17.0]) was taken using dual-frame random digit dialing, stratified for age, sex and geographical area. Professional interviewers carried out computer-assisted telephone interviews (1–30 June 2020). Thirty-day STB was assessed using modified items from the Columbia Suicide Severity Rating Scale. Distal (i.e. pre-pandemic) risk factors included sociodemographic variables, number of physical health conditions and pre-pandemic lifetime mental disorders; proximal (i.e. pandemic) risk factors included current mental disorders and a range of adverse events-experiences related to the pandemic. Logistic regression was used to investigate individual-level associations (odds ratios [OR]) and population-level associations (population attributable risk proportions [PARP]) between risk factors and 30-day STB. All data were weighted using post-stratification survey weights. Results: Estimated prevalence of 30-day STB was 4.5% (1.8% active suicidal ideation; n = 5 [0.1%] suicide attempts). STB was 9.7% among the 34.3% of respondents with pre-pandemic lifetime mental disorders, and 1.8% among the 65.7% without any pre-pandemic lifetime mental disorder. Factors significantly associated with STB were pre-pandemic lifetime mental disorders (total PARP = 49.1%) and current mental disorders (total PARP = 58.4%), i.e. major depressive disorder (OR = 6.0; PARP = 39.2%), generalised anxiety disorder (OR = 5.6; PARP = 36.3%), post-traumatic stress disorder (OR = 4.6; PARP = 26.6%), panic attacks (OR = 6.7; PARP = 36.6%) and alcohol/substance use disorder (OR = 3.3; PARP = 5.9%). Pandemic-related adverse events-experiences associated with STB were lack of social support, interpersonal stress, stress about personal health and about the health of loved ones (PARPs 32.7–42.6%%), and having loved ones infected with COVID-19 (OR = 1.7; PARP = 18.8%). Up to 74.1% of STB is potentially attributable to the joint effects of mental disorders and adverse events−experiences related to the pandemic. Conclusions: STB at the end of the first wave of the Spain COVID-19 pandemic was high, and large proportions of STB are potentially attributable to mental disorders and adverse events−experiences related to the pandemic, including health-related stress, lack of social support and interpersonal stress. There is an urgent need to allocate resources to increase access to adequate mental healthcare, even in times of healthcare system overload. Study registration number: NCT04556565 [ABSTRACT FROM AUTHOR]
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- 2021
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42. Suicidal Thoughts and Behaviors Among First-Year College Students: Results From the WMH-ICS Project
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Mortier, P., Auerbach, R., Alonso, J., Bantjes, J., Benjet, C., Cuijpers, P., Ebert, D., Green, J., Hasking, Penelope, Nock, M., O'Neill, S., Pinder-Amaker, S., Sampson, N., Vilagut, G., Zaslavsky, A., Bruffaerts, R., Kessler, R., Boyes, Mark, Kiekens, G., Baumeister, H., Kaehlke, F., Berking, M., Ramírez, A., Borges, G., Díaz, A., Durán, M., González, R., Gutiérrez-García, R., de la Torre, A., Martinez Martínez, K., Medina-Mora, M., Zarazúa, H., Tarango, G., Zavala Berbena, M., Bjourson, T., Lochner, C., Roos, J., Cur, H., Taljaard, L., Saal, W., Stein, D., Alayo, I., Almenara, J., Ballester, L., Barbaglia, G., Blasco, M., Castellví, P., Cebrià, A., Echeburúa, E., Gabilondo, A., García-Forero, C., Iruin, �., Lagares, C., Miranda-Mendizábal, A., Parès-Badell, O., Pérez-Vázquez, M., Piqueras, J., Roca, M., Rodríguez-Marín, J., Gili, M., Soto-Sanz, V., Vives, M., Mortier, P., Auerbach, R., Alonso, J., Bantjes, J., Benjet, C., Cuijpers, P., Ebert, D., Green, J., Hasking, Penelope, Nock, M., O'Neill, S., Pinder-Amaker, S., Sampson, N., Vilagut, G., Zaslavsky, A., Bruffaerts, R., Kessler, R., Boyes, Mark, Kiekens, G., Baumeister, H., Kaehlke, F., Berking, M., Ramírez, A., Borges, G., Díaz, A., Durán, M., González, R., Gutiérrez-García, R., de la Torre, A., Martinez Martínez, K., Medina-Mora, M., Zarazúa, H., Tarango, G., Zavala Berbena, M., Bjourson, T., Lochner, C., Roos, J., Cur, H., Taljaard, L., Saal, W., Stein, D., Alayo, I., Almenara, J., Ballester, L., Barbaglia, G., Blasco, M., Castellví, P., Cebrià, A., Echeburúa, E., Gabilondo, A., García-Forero, C., Iruin, �., Lagares, C., Miranda-Mendizábal, A., Parès-Badell, O., Pérez-Vázquez, M., Piqueras, J., Roca, M., Rodríguez-Marín, J., Gili, M., Soto-Sanz, V., and Vives, M.
- Abstract
Objective College entrance may be a strategically well-placed “point of capture” for detecting late adolescents with suicidal thoughts and behaviors (STB). However, a clear epidemiological picture of STB among incoming college students is lacking. We present the first cross-national data on prevalence as well as socio-demographic and college-related correlates for STB among first-year college students. Method Web-based self-report surveys were obtained from 13,984 first-year students (response rate 45.5%) across 19 colleges in 8 countries (Australia, Belgium, Germany, Mexico, Northern Ireland, South Africa, Spain, and the United States). Results Lifetime prevalence of suicidal ideation, plans, and attempts was 32.7%, 17.5%, and 4.3%, respectively. The 12-month prevalence was 17.2%, 8.8%, and 1.0%, respectively. About three-fourths of STB cases had onset before the age of 16 years (Q3 = 15.8), with persistence figures in the range of 41% to 53%. About one-half (53.4%) of lifetime ideators transitioned to a suicide plan; 22.1% of lifetime planners transitioned to an attempt. Attempts among lifetime ideators without plan were less frequent (3.1%). Significant correlates of lifetime STB were cross-nationally consistent and generally modest in effect size (median adjusted odds ratio [aOR] = 1.7). Nonheterosexual orientation (aOR range 3.3−7.9) and heterosexual orientation with some same-sex attraction (aOR range 1.9−2.3) were the strongest correlates of STB, and of transitioning from ideation to plans and/or attempts (aOR range 1.6−6.1). Conclusion The distribution of STB in first-year students is widespread, and relatively independent of socio-demographic risk profile. Multivariate risk algorithms based on a high number of risk factors are indicated to efficiently link high-risk status with effective preventive interventions.
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- 2018
43. Population norms for the EQ-5D-3L: a cross-country analysis of population surveys for 20 countries
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Janssen, M.F. (Bas), Szende, A. (A.), Cabasés, J.M. (Juan Manuel), Ramos-Goñi, J.M. (Juan Manuel), Vilagut, G. (G.), König, H.H. (H. H.), Janssen, M.F. (Bas), Szende, A. (A.), Cabasés, J.M. (Juan Manuel), Ramos-Goñi, J.M. (Juan Manuel), Vilagut, G. (G.), and König, H.H. (H. H.)
- Abstract
This study provides EQ-5D population norms for 20 countries (N = 163,838), which can be used to compare profiles for patients with specific conditions with data for the average person in the general population in a similar age and/or gender group. Descriptive EQ-5D data are provided for the total population, by gender and by seven age groups. Provided index values are based on European VAS for all countries, based on TTO for 11 countries and based on VAS for 10 countries. Important differences exist in EQ-5D reported health s
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- 2018
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44. Mental disorder comorbidity and suicidal thoughts and behaviors in the World Health Organization World Mental Health Surveys International College Student initiative
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Auerbach, R., Mortier, P., Bruffaerts, R., Alonso, J., Benjet, C., Cuijpers, P., Demyttenaere, K., Ebert, D., Green, J., Hasking, Penelope, Lee, S., Lochner, C., McLafferty, M., Nock, M., Petukhova, M., Pinder-Amaker, S., Rosellini, A., Sampson, N., Vilagut, G., Zaslavsky, A., Kessler, R., Auerbach, R., Mortier, P., Bruffaerts, R., Alonso, J., Benjet, C., Cuijpers, P., Demyttenaere, K., Ebert, D., Green, J., Hasking, Penelope, Lee, S., Lochner, C., McLafferty, M., Nock, M., Petukhova, M., Pinder-Amaker, S., Rosellini, A., Sampson, N., Vilagut, G., Zaslavsky, A., and Kessler, R.
- Abstract
© 2018 John Wiley & Sons, Ltd. Objectives: Comorbidity is a common feature of mental disorders. However, needs assessment surveys focus largely on individual disorders rather than on comorbidity even though the latter is more important for predicting suicidal thoughts and behaviors. In the current report, we take a step beyond this conventional approach by presenting data on the prevalence and correlates (sociodemographic factors, college-related factors, and suicidal thoughts and behaviors) of the main multivariate profiles of common comorbid Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV disorders among students participating in the first phase of the World Health Organization World Mental Health International College Student initiative. Method: A web-based mental health survey was administered to first year students in 19 colleges across eight countries (Australia, Belgium, Germany, Mexico, Northern Ireland, South Africa, Spain, United States; 45.5% pooled response rate) to screen for seven common DSM-IV mental disorders: major depression, mania/hypomania, generalized anxiety disorder, panic disorder, attention-deficit/hyperactivity disorder, alcohol use disorder, and drug use disorder. We focus on the 14,348 respondents who provided complete data; 38.4% screened positive for at least one 12-month disorder. Results: Multivariate disorder profiles were detected using latent class analysis (LCA). The least common class (C1; 1.9% of students) was made up of students with high comorbidity (four or more disorders, the majority including mania/hypomania). The remaining 12-month cases had profiles of internalizing–externalizing comorbidity (C2; 5.8%), internalizing comorbidity (C3; 14.6%), and pure disorders (C4; 16.1%). The 1.9% of students in C1 had much higher prevalence of suicidal thoughts and behaviors than other students. Specifically, 15.4% of students in C1 made a suicide attempt in the 12 months before the survey compared with 1.3–2.6% of stude
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- 2018
45. WHO world mental health surveys international college student project: Prevalence and distribution of mental disorders
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Auerbach, R., Mortier, P., Bruffaerts, R., Alonso, J., Benjet, C., Cuijpers, P., Demyttenaere, K., Ebert, D., Green, J., Hasking, Penelope, Murray, E., Nock, M., Pinder-Amaker, S., Sampson, N., Stein, D., Vilagut, G., Zaslavsky, A., Kessler, R., Auerbach, R., Mortier, P., Bruffaerts, R., Alonso, J., Benjet, C., Cuijpers, P., Demyttenaere, K., Ebert, D., Green, J., Hasking, Penelope, Murray, E., Nock, M., Pinder-Amaker, S., Sampson, N., Stein, D., Vilagut, G., Zaslavsky, A., and Kessler, R.
- Abstract
© 2018 APA, all rights reserved. Increasingly, colleges across the world are contending with rising rates of mental disorders, and in many cases, the demand for services on campus far exceeds the available resources. The present study reports initial results from the first stage of the WHO World Mental Health International College Student project, in which a series of surveys in 19 colleges across 8 countries (Australia, Belgium, Germany, Mexico, Northern Ireland, South Africa, Spain, United States) were carried out with the aim of estimating prevalence and basic sociodemographic correlates of common mental disorders among first-year college students. Web-based self-report questionnaires administered to incoming first-year students (45.5% pooled response rate) screened for six common lifetime and 12-month DSM-IV mental disorders: major depression, mania/hypomania, generalized anxiety disorder, panic disorder, alcohol use disorder, and substance use disorder. We focus on the 13,984 respondents who were full-time students: 35% of whom screened positive for at least one of the common lifetime disorders assessed and 31% screened positive for at least one 12-month disorder. Syndromes typically had onsets in early to middle adolescence and persisted into the year of the survey. Although relatively modest, the strongest correlates of screening positive were older age, female sex, unmarried-deceased parents, no religious affiliation, nonheterosexual identification and behavior, low secondary school ranking, and extrinsic motivation for college enrollment. The weakness of these associations means that the syndromes considered are widely distributed with respect to these variables in the student population. Although the extent to which cost-effective treatment would reduce these risks is unclear, the high level of need for mental health services implied by these results represents a major challenge to institutions of higher education and governments.
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- 2018
46. The role impairment associated with mental disorder risk profiles in the WHO World Mental Health International College Student Initiative
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Alonso, J., Vilagut, G., Mortier, P., Auerbach, R., Bruffaerts, R., Cuijpers, P., Demyttenaere, K., Ebert, D., Ennis, E., Gutiérrez-García, R., Green, J., Hasking, Penelope, Lee, S., Bantjes, J., Nock, M., Pinder-Amaker, S., Sampson, N., Zaslavsky, A., Kessler, R., Alonso, J., Vilagut, G., Mortier, P., Auerbach, R., Bruffaerts, R., Cuijpers, P., Demyttenaere, K., Ebert, D., Ennis, E., Gutiérrez-García, R., Green, J., Hasking, Penelope, Lee, S., Bantjes, J., Nock, M., Pinder-Amaker, S., Sampson, N., Zaslavsky, A., and Kessler, R.
- Abstract
© 2018 John Wiley & Sons, Ltd. Objective: The objective of this study is to assess the contribution of mental comorbidity to role impairment among college students. Methods: Web-based self-report surveys from 14,348 first-year college students (Response Rate [RR] = 45.5%): 19 universities, eight countries of the World Mental Health International College Student Initiative. We assessed impairment (Sheehan Disability Scales and number of days out of role [DOR] in the past 30 days) and seven 12-month DSM-IV disorders. We defined six multivariate mental disorder classes using latent class analysis (LCA). We simulated population attributable risk proportions (PARPs) of impairment. Results: Highest prevalence of role impairment was highest among the 1.9% of students in the LCA class with very high comorbidity and bipolar disorder (C1): 78.3% of them had severe role impairment (vs. 20.8%, total sample). Impairment was lower in two other comorbid classes (C2 and C3) and successively lower in the rest. A similar monotonic pattern was found for DOR. Both LCA classes and some mental disorders (major depression and panic, in particular) were significant predictors of role impairment. PARP analyses suggest that eliminating all mental disorders might reduce severe role impairment by 64.6% and DOR by 44.3%. Conclusions: Comorbid mental disorders account for a substantial part of role impairment in college students.
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- 2018
47. Severe role impairment associated with mental disorders: Results of the WHO World Mental Health Surveys International College Student Project
- Author
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Alonso, J., Mortier, P., Auerbach, R., Bruffaerts, R., Vilagut, G., Cuijpers, P., Demyttenaere, K., Ebert, D., Ennis, E., Gutiérrez-García, R., Green, J., Hasking, Penelope, Lochner, C., Nock, M., Pinder-Amaker, S., Sampson, N., Zaslavsky, A., Kessler, R., Alonso, J., Mortier, P., Auerbach, R., Bruffaerts, R., Vilagut, G., Cuijpers, P., Demyttenaere, K., Ebert, D., Ennis, E., Gutiérrez-García, R., Green, J., Hasking, Penelope, Lochner, C., Nock, M., Pinder-Amaker, S., Sampson, N., Zaslavsky, A., and Kessler, R.
- Abstract
© 2018 Wiley Periodicals, Inc., a Wiley company. Background: College entrance is a stressful period with a high prevalence of mental disorders. Aims: To assess the role impairment associated with 12-month mental disorders among incoming first-year college students within a large cross-national sample. Methods: Web-based self-report surveys assessing the prevalence of DSM-IV mental disorders and health-related role impairment (Sheehan Disability Scale) were obtained and analyzed from 13,984 incoming first-year college students (Response = 45.5%), across 19 universities in eight countries. Impairment was assessed in the following domains: home management, work (e.g., college-related problems), close personal relationships, and social life. Results: Mean age of the sample was 19.3 (SD = 0.59) and 54.4% were female. Findings showed that 20.4% of students reported any severe role impairment (10% of those without a mental disorder vs. 42.9% of those with at least one disorder, P < 0.01). In bivariate analyses, panic disorder, and mania were associated most frequently with severe impairment (60.6% and 57.5%, respectively). Students reporting three or more mental disorders had almost fivefold more frequently severe impairment relative to those without mental disorders. Multiple logistic regression showed that major depression (OR = 4.0; 95%CI = 3.3, 4.8), generalized anxiety (OR = 3.9; 95%CI = 3.1, 4.8), and panic disorder (OR = 2.9; 95%CI 2.4, 4.2) were associated with the highest odds of severe impairment. Only minimal deviations from these overall associations were found across countries. Conclusion: Mental disorders among first-year college students are associated with substantial role impairment. Providing preventative interventions targeting mental disorders and associated impairments is a critical need for institutions to address.
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- 2018
48. Health conditions and role limitation in three European Regions: a public-health perspective
- Author
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Barbaglia G, Adroher ND, Vilagut G, Bruffaerts R, Bunting B, Caldas de Almeida JM, Florescu S, de Girolamo G, de Graaf R, Haro JM, Hinkov H, Kovess-Masfety V, Matschinger H, and Alonso J
- Subjects
Disability ,Trastornos físicos ,Common health conditions ,Proporción atribuible de riesgo ,Trastornos mentales ,Discapacidad ,Population attributable risk ,Role limitation - Abstract
OBJECTIVE: To describe the distribution of role limitation in the European population aged 18-64 years and to examine the contribution of health conditions to role limitation using a public-health approach. METHODS: Representative samples of the adult general population (n=13,666) aged 18-64 years from 10 European countries of the World Mental Health (WMH) Surveys Initiative, grouped into three regions: Central-Western, Southern and Central-Eastern. The Composite International Diagnostic Interview (CIDI 3.0) was used to assess six mental disorders and standard checklists for seven physical conditions. Days with full and with partial role limitation in the month previous to the interview were reported (WMH-WHODAS). Population Attributable Fraction (PAFs) of full and partial role limitation were estimated. RESULTS: Health conditions explained a large proportion of full role limitation (PAF=62.6%) and somewhat less of partial role limitation (46.6%). Chronic pain was the single condition that consistently contributed to explain both disability measures in all European Regions. Mental disorders were the most important contributors to full and partial role limitation in Central-Western and Southern Europe. In Central-Eastern Europe, where mental disorders were less prevalent, physical conditions, especially cardiovascular diseases, were the highest contributors to disability. CONCLUSION: The contribution of health conditions to role limitation in the three European regions studied is high. Mental disorders are associated with the largest impact in most of the regions. There is a need for mainstreaming disability in the public health agenda to reduce the role limitation associated with health conditions. The cross-regional differences found require further investigation.
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- 2017
49. Population norms for the EQ-5D-3L: a cross-country analysis of population surveys for 20 countries
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Janssen, M. F., primary, Szende, A., additional, Cabases, J., additional, Ramos-Goñi, J. M., additional, Vilagut, G., additional, and König, H. H., additional
- Published
- 2018
- Full Text
- View/download PDF
50. Including information about co-morbidity in estimates of disease burden: results from the World Health Organization World Mental Health Surveys
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Alonso, J., Vilagut, G., Chatterji, S., Heeringa, S., Schoenbaum, M., Bedirhan Üstün, T., Rojas-Farreras, S., Angermeyer, M., Bromet, E., Bruffaerts, R., de Girolamo, G., Gureje, O., Haro, J. M., Karam, A. N., Kovess, V., Levinson, D., Liu, Z., Medina-Mora, M. E., Ormel, J., Posada-Villa, J., Uda, H., Kessler, R. C., Alonso, J., Vilagut, G., Chatterji, S., Heeringa, S., Schoenbaum, M., Bedirhan Üstün, T., Rojas-Farreras, S., Angermeyer, M., Bromet, E., Bruffaerts, R., de Girolamo, G., Gureje, O., Haro, J. M., Karam, A. N., Kovess, V., Levinson, D., Liu, Z., Medina-Mora, M. E., Ormel, J., Posada-Villa, J., Uda, H., and Kessler, R. C.
- Abstract
Background The methodology commonly used to estimate disease burden, featuring ratings of severity of individual conditions, has been criticized for ignoring co-morbidity. A methodology that addresses this problem is proposed and illustrated here with data from the World Health Organization World Mental Health Surveys. Although the analysis is based on self-reports about one's own conditions in a community survey, the logic applies equally well to analysis of hypothetical vignettes describing co-morbid condition profiles. Method Face-to-face interviews in 13 countries (six developing, nine developed; n=31 067; response rate=69.6%) assessed 10 classes of chronic physical and nine of mental conditions. A visual analog scale (VAS) was used to assess overall perceived health. Multiple regression analysis with interactions for co-morbidity was used to estimate associations of conditions with VAS. Simulation was used to estimate condition-specific effects. Results The best-fitting model included condition main effects and interactions of types by numbers of conditions. Neurological conditions, insomnia and major depression were rated most severe. Adjustment for co-morbidity reduced condition-specific estimates with substantial between-condition variation (0.24-0.70 ratios of condition-specific estimates with and without adjustment for co-morbidity). The societal-level burden rankings were quite different from the individual-level rankings, with the highest societal-level rankings associated with conditions having high prevalence rather than high individual-level severity. Conclusions Plausible estimates of disorder-specific effects on VAS can be obtained using methods that adjust for co-morbidity. These adjustments substantially influence condition-specific ratings
- Published
- 2017
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