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The Department for Promotion of Industry & Internal Trade of the Government of India founded the private, nonprofit firm Open Network for Digital Commerce to create open networks for e-commerce. India's e-commerce environment is anticipated to change as a result of the government-imposed Open Network Digital Commerce (ONDC) platform. Customers and sellers will be able to interact and transact online independently of the app or platform they are using. This platform seeks to provide new opportunities, restrain digital monopolies, and assist single proprietors, micro, small, and medium-sized businesses, and other smaller businesses in joining online marketplaces. The purpose of this paper is to illustrate the benefits that ONDC provides to MSMEs—Micro, Small, and MediumSized Enterprise, while simultaneously posing a challenge to the major e-Commerce players yet an advantageous platform to all digital businesses.

Global commercial market forecasted around 45 billion US dollars for refrigeration equipment in 2021. Currently used refrigerants have high global warming potential (GWP); hence, environment-friendly refrigeration system using the Peltier effect is being considered for this research. The thermodynamic refrigeration system has a low coefficient of performance (COP), when compared to chlorofluorocarbon (CFC) and hydrofluorocarbon (HCFC) refrigeration systems. The design of various models of the thermoelectric refrigerator (TER) is created using ANSYS workbench. Each new design is analysed with computational fluid dynamics (CFD) analysis tool by altering insulating materials such as nickel with aluminium foil and polyurethane foam in airflow streamline of thermoelectric refrigeration. Temperature differences obtained between 7.5 and 9.4 °C are tabulated after each run using the finite volume method. Optimization of inner design and insulation material is done by using computational fluid dynamics analysis in the ANSYS FLUENT software. The results of sharp edge design have proved better when compared to partially round edge design and fillet design, 7.85 °C for the cold region and 54.85 °C for the hot region. Further research is expected using the multistage Peltier module and smart temperature control unit to improve the COP of the TER system.

Objectives: To determine the prevalence, association of socio-demographic factors, medical comorbidities with delirium in alcohol dependence syndrome individuals hospitalized during the lockdown period. Design: 667 alcohol-dependent patients attending the institute of mental health, Hyderabad during the 1st phase of lockdown were studied retrospectively with the help of hospital records. Results: Out of 667 samples 266 individuals presented with delirium. There is no significance of sociodemographic factors on delirium except sex. There is a positive correlation between severity of dependence (r=0.26, p=0.000), number of drinks (r=0.271, p=0.000) per day, duration of intake of substance (r=0.137, p=0.000) with delirium. Individuals with medical comorbidity hypertension, both hypertension and diabetes have presented a greater number of delirium cases. Conclusion: Current lockdown scenario is the first time we had faced. We found a greater prevalence of delirium in alcohol dependence cases which is a threat to the health care system. Hence further research in risk factors involving delirium presentation is needed. Stringent rules to control alcohol dependence to avoid a similar situation in the future and effective management of health care facilities are needed. Keywords: Alcohol dependence syndrome, Prevalence, Delirium.

In this experimental study, Aluminium alloy (AA) 6082 was strengthened with Tungsten Carbide and graphite through stir casting technique. Scanning Electron Microscope (SEM) was employed to study the wear performance of the Al/WC/Gr composites. Wear tests were carried out using a pin-ondisc apparatus. The input parameters in this study are the load applied (4, 8, 12, 16, and 20 kg), speed of sliding (1, 1.5, 2, 2.5 and 3 m/s) and distance slides (1000, 1500, 2000 and 2500 m). Response Surface Methodology (RSM) has been carried the use of MINITAB 14 software program to examine the rate of wear and frictional behaviour of the hybrid composites.

Introduction: Postnatal depression (PND) is a common psychiatric disorder and is considered a serious public health issue. It is diagnosed in about 50% of the women during first year after delivery. Objective: To assess the prevalence of PND and study the associated risk factors. Materials and Methods: The study was conducted in government Obstetrics & Gynecology Hospital in Khammam, Telangana from September 2016 to March 2017. A total of 150 women after delivery were included in the study. A semi structured proforma for socio-demographic details and the Edinburg Postnatal Depression Scale (EPDS) for screening for depressive symptoms were used to collect data from women between 1st and 8th postpartum weeks. Institutes ethics committee approval was taken and consent taken from study participants. Results: Prevalence of PND was 24%. PND showed significant association with primiparous women, husband’s occupation, unplanned pregnancy and women who preferred male child but gave birth to a female child. Conclusion: PND screening should be an integral part of postnatal care, so that they are counseled early, thereby preventing future complications. Keywords: Postnatal depression (PND), Edinburg postnatal depression scale (EPDS), Postpartum.

The current study was undertaken to evaluate the clinical efficacy of Titanium Dynamic Compression plate for repair of femur fractures in dogs. This study was conducted on six dogs presented with fractures to the Department of Veterinary Surgery and Radiology at the College of Veterinary Science, Hyderabad. The six cases of fractures were diagnosed by clinical signs, orthopaedic examination and survey radiography. The symptoms observed in the dogs presented for treatment were pain on manipulation, abnormal angulation and lameness immediately after trauma, swelling, non-weight bearing, dangling of the limb and crepitation at the fracture site. Pre-operative radiographic examination in plain orthogonal views, i.e., cranio-caudal and medio-lateral radiographs revealed diaphyseal fractures in all dogs. Pre-operative radiographs also showed the type of fractures as distal transverse fracture of femur in two dogs, mid shaft diaphyseal transverse femur fracture in two dogs, proximal oblique femur fracture in one dog and mid shaft oblique femur fracture in 2 dogs. All fractures are closed, three in right hindlimb and two in left hindlimb and one dog had bilateral femur fracture. These fractures were stabilized with 2.7 mm Titanaium DCP in one dog and 3.5 mm Titanium DCP in five dogs. Good implant stability throughout the treatment period without any complications was achieved all dogs. In all six dogs in the present study showed partial weight bearing on the 1st post- operative day. All six dogs showed normal weight bearing at rest, the weight bearing of the affected limb while walking from 2nd Post-operative day in one dog, 3rd Post-operative day in one dog, 5th Post-operative day in two dogs, 7th Post-operative day in one dogs and 8th Post-operative day in one dog. All six dogs achieved complete weight bearing by 15th post-operative day. i.e. from Grade V to Grade I. The mean age of the all dogs to bear the complete weight on the affected limb were seen on 5.0±2.28 days. The radiographs obtained on 30th day Post-operative day revealed proper apposition, decreased fracture gap, appearance of progressive bridging callus with adequate radio-density in all 6 dogs, and on 60th day revealed continuity of complete cortiomedullary cavity and compete bone formation without any complications with fast healing. Based on present study, it was concluded that Titanium Dynamic compression plating was successful in the treatment of femur fractures in dogs as it is lighter in weight, had superior fatique and corrosive resistance, improved biocompatibility and lower young’s modulus.

A series of seven coumarinyl-amino acid ester conjugates have been synthesized and characterized by NMR (1H and 13C) and mass spectra. Further, the compounds were investigated for their therapeutic applications such as anti-inflammatory and antioxidant activities. Among the synthesized compounds most of the analogs showed good efficiency compared with the standard.

This paper presents a single switch based Integrated Boost series parallel fly-back converter has been presented. In the proposed converter the conversion efficiency of power is improved and the switching stress of the MOSFET switch is also reduced. In this converter there are two sub-stages. One is boost-fly-back semi stage which improves power transfer from input to load. The second one is dc-dc fly-back semi stage that provides good output voltage regulation. The bulk capacitors are connected in series with primary windings of 2:1 fly-back transformer which reduces switch stress and improves voltage regulation; the parallel connection improves the efficiency. The Operating modes of Integrated Boost Series Parallel Fly-Back Converter (IBSPFC) have been investigated. Additionally the computation process of bulk capacitor voltage, fly-back inductance and other key parameters are also presented. Also in this paper, a voltage mode control is used to control the MOSFET switch of IBSPFC which provides good voltage regulation. Simulation has been carried out on 25V input, 150Voutput and 200W isolated dc-dc converter functioning at 100 kHz frequency and the results are presented. Simulation results show the performance Improvement of proposed controller.