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106 results on '"Vigeland, Magnus Dehli"'

2. Correlation between gene expression and MRI STIR signals in patients with chronic low back pain and Modic changes indicates immune involvement

Author

Vigeland, Maria Dehli, Flåm, Siri Tennebø, Vigeland, Magnus Dehli, Espeland, Ansgar, Kristoffersen, Per Martin, Vetti, Nils, Wigemyr, Monica, Bråten, Lars Christian Haugli, Gjefsen, Elisabeth, Schistad, Elina Iordanova, Haugen, Anne Julsrud, Froholdt, Anne, Skouen, Jan Sture, Zwart, John-Anker, Storheim, Kjersti, Pedersen, Linda Margareth, and Lie, Benedicte Alexandra

Published
2022
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16. Tropical complete intersection curves

Author

Vigeland, Magnus Dehli

Subjects
Mathematics - Algebraic Geometry, Mathematics - Combinatorics
Abstract

A tropical complete intersection curve C in R^(n+1) is a transversal intersection of n smooth tropical hypersurfaces. We give a formula for the number of vertices of C given by the degrees of the tropical hypersurfaces. We also compute the genus of C (defined as the number of independent cycles of C) when C is smooth and connected., Comment: 13 pages, 7 figures

Published
2007

17. Tropical Lines on Cubic Surfaces

Author

Panizzut, Marta and Vigeland, Magnus Dehli

Subjects
Mathematics - Algebraic Geometry, Mathematics - Combinatorics
Abstract

Given a tropical line $L$ and a smooth tropical surface $X$, we look at the position of $L$ on $X$. We introduce its primal and dual motif which are respectively a decorated graph and a subcomplex of the dual triangulation of $X$. They encode the combinatorial position of $L$ on $X$. We classify all possible motifs of tropical lines on general smooth tropical surfaces. This classification allows to give an upper bound for the number of tropical lines on a general smooth tropical surface with a given subdivision. We focus in particular on surfaces of degree three. As a concrete example, we look at tropical cubic surfaces dual to a fixed honeycomb triangulation, showing that a general surface contains exactly $27$ tropical lines., Comment: Major updates of the previous version: Completed the classification, changed the title and added co-author. See Introduction for further details

Published
2007

18. Smooth tropical surfaces with infinitely many tropical lines

Author

Vigeland, Magnus Dehli

Subjects
Mathematics - Algebraic Geometry, Mathematics - Combinatorics
Abstract

We study the tropical lines contained in smooth tropical surfaces in R^3. On smooth tropical quadric surfaces we find two one-dimensional families of tropical lines, like in classical algebraic geometry. Unlike the classical case, however, there exist smooth tropical surfaces of any degree with infinitely many tropical lines., Comment: 27 pages, 12 figures. v2: Errors corrected, notation improved, referances added, Example 9.3 new

Published
2007

19. The group law on a tropical elliptic curve

Author

Vigeland, Magnus Dehli

Subjects
Mathematics - Algebraic Geometry, Mathematics - Combinatorics
Abstract

In analogy with the classical group law on a plane cubic curve, we define a group law on a smooth plane tropical cubic curve. We show that the resulting group is isomorphic to $S^1$., Comment: 13 pages, latex2e, 5 figures as pstex and pstex_t files

Published
2004

26. Long-Term Use of Amoxicillin Is Associated with Changes in Gene Expression and DNA Methylation in Patients with Low Back Pain and Modic Changes.

Author

Vigeland, Maria Dehli, Flåm, Siri Tennebø, Vigeland, Magnus Dehli, Espeland, Ansgar, Zucknick, Manuela, Wigemyr, Monica, Bråten, Lars Christian Haugli, Gjefsen, Elisabeth, Zwart, John-Anker, Storheim, Kjersti, Pedersen, Linda Margareth, Selmer, Kaja, Lie, Benedicte Alexandra, and Gervin, Kristina

Subjects
LUMBAR pain, DNA methylation, GENE expression, EPIGENOMICS, AMOXICILLIN, IMMUNOGLOBULIN genes
Abstract

Long-term antibiotics are prescribed for a variety of medical conditions, recently including low back pain with Modic changes. The molecular impact of such treatment is unknown. We conducted longitudinal transcriptome and epigenome analyses in patients (n = 100) receiving amoxicillin treatment or placebo for 100 days in the Antibiotics in Modic Changes (AIM) study. Gene expression and DNA methylation were investigated at a genome-wide level at screening, after 100 days of treatment, and at one-year follow-up. We identified intra-individual longitudinal changes in gene expression and DNA methylation in patients receiving amoxicillin, while few changes were observed in patients receiving placebo. After 100 days of amoxicillin treatment, 28 genes were significantly differentially expressed, including the downregulation of 19 immunoglobulin genes. At one-year follow-up, the expression levels were still not completely restored. The significant changes in DNA methylation (n = 4548 CpGs) were mainly increased methylation levels between 100 days and one-year follow-up. Hence, the effects on gene expression occurred predominantly during treatment, while the effects on DNA methylation occurred after treatment. In conclusion, unrecognized side effects of long-term amoxicillin treatment were revealed, as alterations were observed in both gene expression and DNA methylation that lasted long after the end of treatment. [ABSTRACT FROM AUTHOR]

Published
2023
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28. Tropical Lines on Cubic Surfaces

Author

Panizzut, Marta and Vigeland, Magnus Dehli

Subjects
Mathematics - Algebraic Geometry, General Mathematics, FOS: Mathematics, Mathematics - Combinatorics, Combinatorics (math.CO), Algebraic Geometry (math.AG), Physics::Atmospheric and Oceanic Physics
Abstract

Given a tropical line $L$ and a smooth tropical surface $X$, we look at the position of $L$ on $X$. We introduce its primal and dual motif which are respectively a decorated graph and a subcomplex of the dual triangulation of $X$. They encode the combinatorial position of $L$ on $X$. We classify all possible motifs of tropical lines on general smooth tropical surfaces. This classification allows to give an upper bound for the number of tropical lines on a general smooth tropical surface with a given subdivision. We focus in particular on surfaces of degree three. As a concrete example, we look at tropical cubic surfaces dual to a fixed honeycomb triangulation, showing that a general surface contains exactly $27$ tropical lines., Comment: Major updates of the previous version: Completed the classification, changed the title and added co-author. See Introduction for further details

Published
2022

31. Autosomal Recessive Cerebellar Atrophy and Spastic Ataxia in Patients With Pathogenic Biallelic Variants in GEMIN5

Author

Rajan, Deepa S., primary, Kour, Sukhleen, additional, Fortuna, Tyler R., additional, Cousin, Margot A., additional, Barnett, Sarah S., additional, Niu, Zhiyv, additional, Babovic-Vuksanovic, Dusica, additional, Klee, Eric W., additional, Kirmse, Brian, additional, Innes, Micheil, additional, Rydning, Siri Lynne, additional, Selmer, Kaja K., additional, Vigeland, Magnus Dehli, additional, Erichsen, Anne Kjersti, additional, Nemeth, Andrea H., additional, Millan, Francisca, additional, DeVile, Catherine, additional, Fawcett, Katherine, additional, Legendre, Adrien, additional, Sims, David, additional, Schnekenberg, Ricardo Parolin, additional, Burglen, Lydie, additional, Mercier, Sandra, additional, Bakhtiari, Somayeh, additional, Francisco-Velilla, Rosario, additional, Embarc-Buh, Azman, additional, Martinez-Salas, Encarnacion, additional, Wigby, Kristen, additional, Lenberg, Jerica, additional, Friedman, Jennifer R., additional, Kruer, Michael C., additional, and Pandey, Udai Bhan, additional

Published
2022
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32. Whole‐exome sequencing in syndromic craniosynostosis increases diagnostic yield and identifies candidate genes in osteogenic signaling pathways

Author

Tønne, Elin, primary, Due‐Tønnessen, Bernt Johan, additional, Vigeland, Magnus Dehli, additional, Amundsen, Silja Svanstrøm, additional, Ribarska, Teodora, additional, Åsten, Pamela Marika, additional, Sheng, Ying, additional, Helseth, Eirik, additional, Gilfillan, Gregor Duncan, additional, Mero, Inger‐Lise, additional, and Heimdal, Ketil Riddervold, additional

Published
2022
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33. Two-locus identity coefficients in pedigrees.

Author

Vigeland, Magnus Dehli

Subjects
*GENEALOGY, *KINSHIP, *GENETICS, *ALGORITHMS
Abstract

This paper proposes a solution to a long-standing problem concerning the joint distribution of allelic identity by descent between two individuals at two linked loci. Such distributions have important applications across various fields of genetics, and detailed formulas for selected relationships appear scattered throughout the literature. However, these results were obtained essentially by brute force, with no efficient method available for general pedigrees. The recursive algorithm described in this paper, and its implementation in R, allow efficient calculation of two-locus identity coefficients in any pedigree. As a result, many existing procedures and techniques may, for the first time, be applied to complex and inbred relationships. Two such applications are discussed, concerning the expected likelihood ratio in forensic kinship testing, and variances in realized relatedness. [ABSTRACT FROM AUTHOR]

Published
2023
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37. A novel somatic mutation inGNB2provides new insights to the pathogenesis of Sturge–Weber syndrome

Author

Fjær, Roar, primary, Marciniak, Katarzyna, additional, Sundnes, Olav, additional, Hjorthaug, Hanne, additional, Sheng, Ying, additional, Hammarström, Clara, additional, Sitek, Jan Cezary, additional, Vigeland, Magnus Dehli, additional, Backe, Paul Hoff, additional, Øye, Ane-Marte, additional, Fosse, Johanna Hol, additional, Stav-Noraas, Tor Espen, additional, Uchiyama, Yuri, additional, Matsumoto, Naomichi, additional, Comi, Anne, additional, Pevsner, Jonathan, additional, Haraldsen, Guttorm, additional, and Selmer, Kaja Kristine, additional

Published
2021
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43. Benefits of clinical criteria and high-throughput sequencing for diagnosing children with syndromic craniosynostosis

Author

Tønne, Elin, primary, Due-Tønnessen, Bernt Johan, additional, Mero, Inger-Lise, additional, Wiig, Ulrikke Straume, additional, Kulseth, Mari Ann, additional, Vigeland, Magnus Dehli, additional, Sheng, Ying, additional, von der Lippe, Charlotte, additional, Tveten, Kristian, additional, Meling, Torstein Ragnar, additional, Helseth, Eirik, additional, and Heimdal, Ketil Riddervold, additional

Published
2020
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49. Pathogenic variants inKCTD7perturb neuronal K+fluxes and glutamine transport

Author

Moen, Marivi Nabong, primary, Fjær, Roar, additional, Hamdani, El Hassan, additional, Laerdahl, Jon K., additional, Menchini, Robin Johansen, additional, Vigeland, Magnus Dehli, additional, Sheng, Ying, additional, Undlien, Dag Erik, additional, Hassel, Bjørnar, additional, Salih, Mustafa A., additional, El Khashab, Heba Y., additional, Selmer, Kaja Kristine, additional, and Chaudhry, Farrukh Abbas, additional

Published
2016
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