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1. Effect of adherence to primaquine on the risk of Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis

Author

Mehdipour, Parinaz, Rajasekhar, Megha, Dini, Saber, Zaloumis, Sophie, Abreha, Tesfay, Adam, Ishag, Awab, Ghulam Rahim, Baird, J. Kevin, Brasil, Larissa W., Chu, Cindy S., Cui, Liwang, Daher, André, do Socorro M Gomes, Margarete, Gonzalez‑Ceron, Lilia, Hwang, Jimee, Karunajeewa, Harin, Lacerda, Marcus V. G., Ladeia-Andrade, Simone, Leslie, Toby, Ley, Benedikt, Lidia, Kartini, Llanos-Cuentas, Alejandro, Longley, Rhea J., Monteiro, Wuelton Marcelo, Pereira, Dhelio B., Rijal, Komal Raj, Saravu, Kavitha, Sutanto, Inge, Taylor, Walter R. J., Thanh, Pham Vinh, Thriemer, Kamala, Vieira, José Luiz F., White, Nicholas J., Zuluaga-Idarraga, Lina M., Guerin, Philippe J., Price, Ric N., Simpson, Julie A., and Commons, Robert J.

Published
2023
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2. Effect of primaquine dose on the risk of recurrence in patients with uncomplicated Plasmodium vivax: a systematic review and individual patient data meta-analysis

Author

Adhikari, Bipin, Anstey, Nicholas M, Assefa, Ashenafi, Boyd, Sarah C, Chau, Nguyen Hoang, Day, Nicholas PJ, Degaga, Tamiru Shibiru, Dondorp, Arjen M, Erhart, Annette, Ferreira, Marcelo Urbano, Ghimire, Prakash, Green, Justin A, Koh, Gavin CKW, Mekuria, Asrat Hailu, Mueller, Ivo, Naadim, Mohammad Nader, Nelwan, Erni J, Nosten, Francois, Price, David J, Sattabongkot, Jetsumon, Stepniewska, Kasia, von Seidlein, Lorenz, William, Timothy, Woodrow, Charles J, Woyessa, Adugna, Commons, Robert J, Rajasekhar, Megha, Edler, Peta, Abreha, Tesfay, Awab, Ghulam R, Baird, J Kevin, Barber, Bridget E, Chu, Cindy S, Cui, Liwang, Daher, André, Gonzalez-Ceron, Lilia, Grigg, Matthew J, Hwang, Jimee, Karunajeewa, Harin, Lacerda, Marcus V G, Ladeia-Andrade, Simone, Lidia, Kartini, Llanos-Cuentas, Alejandro, Longley, Rhea J, Pereira, Dhelio B, Pasaribu, Ayodhia P, Pukrittayakamee, Sasithon, Rijal, Komal R, Sutanto, Inge, Taylor, Walter R J, Thanh, Pham V, Thriemer, Kamala, Vieira, José Luiz F, Watson, James A, Zuluaga-Idarraga, Lina M, White, Nicholas J, Guerin, Philippe J, Simpson, Julie A, and Price, Ric N

Published
2024
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3. Monoamine oxidase-A (MAO-A) low-expression variants and increased risk of Plasmodium vivax malaria relapses.

Author

Puça, Maria Carolina Silva De Barros, Rodrigues, Danielle Fonseca, Salazar, Yanka Evellyn Alves Rodrigues, Louzada, Jaime, Fontes, Cor Jesus Fernandes, Daher, André, Pereira, Dhélio Batista, Vieira, José Luiz Fernandes, Carvalho, Luzia Helena, Brito, Cristiana Ferreira Alves de, Gil, José Pedro, and Sousa, Tais Nobrega de

Subjects
CYTOCHROME P-450, CYTOCHROME P-450 CYP2D6, PLASMODIUM vivax, MALARIA, GENETIC polymorphisms
Abstract

Objectives Primaquine is essential for the radical cure of Plasmodium vivax malaria and must be metabolized into its bioactive metabolites. Accordingly, polymorphisms in primaquine-metabolizing enzymes can impact the treatment efficacy. This pioneering study explores the influence of monoamine oxidase-A (MAO-A) on primaquine metabolism and its impact on malaria relapses. Methods Samples from 205 patients with P. vivax malaria were retrospectively analysed by genotyping polymorphisms in MAO-A and cytochrome P450 2D6 (CYP2D6) genes. We measured the primaquine and carboxyprimaquine blood levels in 100 subjects for whom blood samples were available on the third day of treatment. We also examined the relationship between the enzyme variants and P. vivax malaria relapses in a group of subjects with well-documented relapses. Results The median carboxyprimaquine level was significantly reduced in individuals carrying low-expression MAO-A alleles plus impaired CYP2D6. In addition, this group experienced significantly more P. vivax relapses. The low-expression MAO-A status was not associated with malaria relapses when CYP2D6 had normal activity. This suggests that the putative carboxyprimaquine contribution is irrelevant when the CYP2D6 pathway is fully active. Conclusions We found evidence that the low-expression MAO-A variants can potentiate the negative impact of impaired CYP2D6 activity, resulting in lower levels of carboxyprimaquine metabolite and multiple relapses. The findings support the hypothesis that carboxyprimaquine may be further metabolized through CYP-mediated pathways generating bioactive metabolites that act against the parasite. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Sex Differences in Revascularization, Treatment Goals, and Outcomes of Patients With Chronic Coronary Disease: Insights From the ISCHEMIA Trial

Author

Reynolds, Harmony R., primary, Cyr, Derek D., additional, Merz, C. Noel Bairey, additional, Shaw, Leslee J., additional, Chaitman, Bernard R., additional, Boden, William E., additional, Alexander, Karen P., additional, Rosenberg, Yves D., additional, Bangalore, Sripal, additional, Stone, Gregg W., additional, Held, Claes, additional, Spertus, John, additional, Goetschalckx, Kaatje, additional, Bockeria, Olga, additional, Newman, Jonathan D., additional, Berger, Jeffrey S., additional, Elghamaz, Ahmed, additional, Lopes, Renato D., additional, Min, James K., additional, Berman, Daniel S., additional, Picard, Michael H., additional, Kwong, Raymond Y., additional, Harrington, Robert A., additional, Thomas, Boban, additional, O'Brien, Sean M., additional, Maron, David J., additional, Hochman, Judith S., additional, Mavromatis, Kreton, additional, Linefsky, Jason, additional, Miller, Todd, additional, Banerjee, Subhash, additional, Reynolds, Harmony R., additional, Donnino, Robert M., additional, Phillips, Lawrence M., additional, Saric, Muhamed, additional, Abdul‐Nour, Khaled, additional, Stone, Peter H., additional, Jang, James J., additional, Yee, Gennie, additional, Weitz, Steven, additional, Arnold, Suzanne, additional, O’Keefe, James Henry, additional, Shapiro, Michael D., additional, El‐Hajjar, Mohammad, additional, Sidhu, Mandeep S., additional, Fein, Steven A., additional, Torosoff, Mikhail T., additional, Lyubarova, Radmila, additional, Mookherjee, Sulagna, additional, Drzymalski, Krzysztof, additional, McFalls, Edward O., additional, Garcia, Santiago A., additional, Bertog, Stefan C., additional, Siddiqui, Rizwan A., additional, Ishani, Areef, additional, Hansen, Ronnell A., additional, Khouri, Michel Georges, additional, Goldberg, Jonathan L., additional, Goldweit, Richard, additional, Cohen, Ronny A., additional, Mirrer, Brooks, additional, Navarro, Victor, additional, Winchester, David E., additional, Kronenberg, Marvin, additional, Rogal, Philip, additional, McFarren, Christopher, additional, Heitner, John F., additional, Dauber, Ira M., additional, Cannan, Charles, additional, Sudarshan, Sriram, additional, Mehta, Puja K., additional, McDaniel, Michael, additional, Lerakis, Stamatios, additional, Quyyumi, Arshed, additional, Wenger, Nanette K., additional, Hedgepeth, Chester M., additional, Hurlburt, Heather, additional, Rosen, Alan, additional, Sahul, Zakir, additional, Booth, David, additional, Leung, Steve, additional, Abdel‐Latif, Ahmed, additional, Reda, Hassan, additional, Ziada, Khaled, additional, Setty, Sampoornima, additional, Barua, Rajat S., additional, Hage, Fadi, additional, Caldeira, Christiano, additional, Davies, James E., additional, Leesar, Massoud, additional, Heo, Jaekyeong, additional, Iskandrian, Amy, additional, Al Solaiman, Firas, additional, Singh, Satinder, additional, Dajani, Khaled, additional, Der Mesropian, Paul, additional, Sacco, Joseph, additional, McCandless, Brian, additional, Orgera, Marisa, additional, Arif, Imran, additional, Kerr, Hanan, additional, Trejo (Gutierrez), Jorge F., additional, Fletcher, Gerald, additional, Lane, Gary E., additional, Neeson, Lynn M., additional, Parikh, Pragnesh P., additional, Pollak, Peter M., additional, Shapiro, Brian P., additional, Landolfo, Kevin, additional, Gemignani, Anthony, additional, O’Rourke, Daniel, additional, Meadows, Judith L., additional, Call, Jason T., additional, Hannan, Joseph, additional, Bojar, Robert, additional, Kumar, Deepti, additional, Mukai, John, additional, Martin, Edward T., additional, Vorobiof, Gabriel, additional, Moorman, Alec, additional, Kinlay, Scott, additional, Hamburger, Robert J., additional, Rocco, Thomas P., additional, Bhatt, Deepak L., additional, Croce, Kevin, additional, Quin, Jacquelyn A., additional, Anumpa, Jati, additional, Zenati, Marco, additional, Faxon, David P., additional, Rayos, Glenn, additional, Seedhom, Ashraf, additional, Sullenberger, Lance, additional, Kumkumian, Gregory, additional, Sedlis, Steven P., additional, Donnino, Robert M., additional, Lorin, Jeffrey, additional, Tamis‐Holland, Jacqueline E., additional, Kornberg, Robert, additional, Leber, Robert, additional, Saba, Souheil, additional, Lee, Michael W., additional, Small, Delano R., additional, Nona, Wassim, additional, Alexander, Patrick B., additional, Rehman, Iram, additional, Badami, Umesh, additional, Marzo, Kevin, additional, Robbins, Inga H., additional, Levite, Howard A., additional, Shetty, Sanjay, additional, Patel, Mayuri, additional, Hamroff, Glenn S., additional, Little, Raymond W., additional, Zimbelman, Brandi D., additional, Lui, Charles Y., additional, Smith, Brigham R., additional, Vezina, Daniel P., additional, Khor, Lillian L., additional, Abraham, Josephine D., additional, Bull, David A., additional, McKellar, Stephen H., additional, Kotter, John, additional, Hu, Bob, additional, Labovitz, Arthur J., additional, Berlowitz, Michael, additional, Matar, Fadi, additional, Rodriguez, Fatima, additional, Schnittger, Ingela, additional, Fearon, William F., additional, Deedwania, Prakash, additional, Reddy, Kiran, additional, Sweeny, Joseph, additional, Spizzieri, Christopher, additional, Hochberg, Claudia P., additional, Salerno, William D., additional, Wyman, Ray, additional, Zarka, Amer, additional, Shah, Anil V., additional, Haldis, Thomas, additional, Kohn, Jeffrey A., additional, Girotra, Saket, additional, Almousalli, Omar, additional, Krishnam, Mayil S., additional, Milliken, Jeffrey C., additional, Patel, Pranav M., additional, Seto, Arnold H., additional, Harley, Kevin T., additional, Gibson, Michael A., additional, Allen, Byron J., additional, Coram, Rita, additional, Thomas, Sabu, additional, Schwartz, Ronald G., additional, Chen, Wei, additional, El Shahawy, Mahfouz, additional, Stafford, James, additional, Abernethy, William B., additional, Zurick, Andrew, additional, Meyer, Thomas M., additional, Morford, Ronald G., additional, Rutkin, Bruce, additional, Bokhari, Sabahat, additional, Sokol, Seth I., additional, Meisner, Jay, additional, Hamzeh, Ihab, additional, Misra, Arunima, additional, Wall, Matthew, additional, De Rosen, Veronica Lenges, additional, Alam, Mahboob, additional, Turner, Michael C., additional, Mulhearn, Thomas J., additional, Good, Arnold P., additional, Shammas, Nicolas W., additional, Chilton, Robert, additional, Nguyen, Patricia K., additional, Jezior, Matthew, additional, Gordon, Paul C., additional, Crain, Thomas, additional, Stenberg, Robert, additional, Pedalino, Ronald P., additional, Wiesel, Joseph, additional, Juang, George J., additional, Al‐Amoodi, Mohammed, additional, Wohns, David, additional, Lader, Ellis W., additional, Mumma, Michael, additional, Dharmarajan, Lekshmi, additional, McGarvey, Joseph F. X., additional, Downes, Thomas R., additional, Luckasen, Gary J., additional, Cheong, Benjamin, additional, Potluri, Srinivasa, additional, Mastouri, Ronald A., additional, Breall, Jeffery A., additional, Revtyak, George E., additional, Bazeley, Jonathan W., additional, Li, Dayuan, additional, Giedd, Kenneth, additional, Old, Wayne, additional, Burt, Francis, additional, Sokhon, Kozhaya, additional, Gopal, Deepika, additional, Valeti, Uma S., additional, Kobashigawa, Jon, additional, Govindan, Sajeev Chakanalil, additional, Nair, Rajesh Gopalan, additional, Manjunath, Cholenahally Nanjappa, additional, Moorthy, Nagaraja, additional, Manjunath, Satvic Cholenahally, additional, Narayanappa, Suryaprakash, additional, Pandit, Neeraj, additional, Nath, Ranjit Kumar, additional, Dwivedi, S. K., additional, Narain, V. S., additional, Chandra, Sharad, additional, Wander, Gurpreet S., additional, Tandon, Rohit, additional, Ralhan, Sarju, additional, Aslam, Naved, additional, Goyal, Abhishek, additional, Bhargava, Balram, additional, Karthikeyan, G., additional, Ramakrishnan, S., additional, Seth, Sandeep, additional, Yadav, Rakesh, additional, Singh, Sandeep, additional, Roy, Ambuj, additional, Parakh, Neeraj, additional, Verma, Sunil Kumar, additional, Narang, Rajiv, additional, Mishra, Sundeep, additional, Naik, Nitish, additional, Sharma, Gautam, additional, Choudhary, Shiv Kumar, additional, Patel, Chetan, additional, Gulati, Gurpreet, additional, Sharma, Sanjeev, additional, Bahl, V. K., additional, Mathew, Anoop, additional, Punnoose, Eapen, additional, Gadkari, Milind Avdhoot, additional, Gadage, Siddharth, additional, Pillay, Tapan Umesh, additional, Satheesh, Santhosh, additional, Mathur, Atul, additional, Kaul, Upendra, additional, Christopher, Johann, additional, Menon, Rajeev, additional, Kumar, Nirmal, additional, Oomman, Abraham, additional, Mao, Robert, additional, Solomon, Hilda, additional, Naik, Sudhir, additional, Khan, Sajeeda Parveen, additional, Grant, Purvez, additional, Kachru, Ranjan, additional, Ajit Kumar, V. K., additional, Ganapathi, Sanjay, additional, Jayakumar, K., additional, Sivadasanpillai, Harikrishnan, additional, Sasidharan, Bijulal, additional, Kapilamoorthy, T. R., additional, Polamuri, Praneeth, additional, Senior, Roxy, additional, Gurunathan, Sothinathan, additional, Karogiannis, Nikolaos, additional, Shah, Benoy N., additional, Trimlett, Richard HJ, additional, Rubens, Michael B., additional, Nicol, Edward D., additional, Mittal, Tarun K., additional, Hampson, Reinette, additional, Gamma, Reto Andreas, additional, de Belder, Mark A., additional, Thambyrajah, Jeet, additional, Nageh, Thuraia, additional, Davies, John R., additional, Lindsay, Steven J., additional, Kurian, John, additional, Jamil, Haqeel, additional, Raheem, Osama, additional, Hoye, Angela, additional, Donnelly, Patrick, additional, Valecka, Bernardas, additional, Chauhan, Anoop, additional, Barr, Craig, additional, Alfakih, Khaled, additional, Byrne, Jonathan, additional, Webb, Ian, additional, Henriksen, Peter, additional, OKane, Peter, additional, de Silva, Ramesh, additional, Conway, Dwayne S. G., additional, Sirker, Alexander A, additional, Hoole, Stephen P., additional, Witherow, Fraser N., additional, Johnston, Nicola, additional, Harbinson, Mark, additional, Walsh, Simon, additional, Douglas, Hanna, additional, Luckie, Matthew, additional, Sobolewska, Jolanta, additional, Jeetley, Paramjit, additional, Patel, Niket, additional, Kotecha, Tushar, additional, Travill, Christopher, additional, Karimullah, Iqbal, additional, Al‐Bustami, Mahmud, additional, Braganza, Denise, additional, Henderson, Robert, additional, Pointon, Kate, additional, Naik, Surendra, additional, Mathew, Thomas, additional, Berry, Colin, additional, Collison, Damien, additional, Roditi, Giles, additional, Moriarty, Andrew J., additional, Glover, Jason D., additional, Pradhan, Jiwan, additional, Mikhail, Ghada, additional, Francis, Darrel P., additional, Gosselin, Gilbert, additional, Diaz, Ariel, additional, Rheault, Philippe, additional, Barrero, Miguel, additional, Gagné, Carl‐Éric, additional, Pépin‐Dubois, Yanek, additional, Costa, Ricardo, additional, Sia, Ying Tung, additional, Lemay, Catherine, additional, Gisbert, Alejandro, additional, Gervais, Pierre, additional, Rheault, Alain, additional, Phaneuf, Denis Carl, additional, Garg, Pallav, additional, Chow, Benjamin J. W., additional, Hessian, Renee C., additional, Beanlands, Rob S., additional, Davies, Richard F., additional, Bainey, Kevin R., additional, Cheema, Asim N., additional, Bagai, Akshay, additional, Wald, Ron, additional, Goodman, Shaun, additional, Graham, John Joseph, additional, Peterson, Mark, additional, Chow, Chi‐Ming, additional, Abramson, Beth, additional, Cheema, Asim Nazir, additional, Vakani, Mohammad Tariq, additional, Cha, James, additional, Howarth, Andrew G, additional, Wong, Graham, additional, Uxa, Amar, additional, Galiwango, Paul, additional, Kassam, Saleem, additional, Mukherjee, Ashok, additional, Ricci, A. Joseph, additional, Lam, Andy, additional, Mehta, Shamir, additional, Udell, Jacob, additional, Généreux, Philippe, additional, Hameed, Adnan, additional, Daba, Ledjalem, additional, Hueb, Whady, additional, Rezende, Paulo Cury, additional, Silva, Expedito Eustáquio Ribeiro, additional, Hueb, Alexandre Ciappina, additional, Smanio, Paola Emanuela Poggio, additional, de Quadros, Alexandre Schaan, additional, Kalil, Renato Abdala Karam, additional, da Costa Vieira, José Luiz, additional, Grossmann, Gabriel, additional, de Oliveira, Pedro Píccaro, additional, Bridi, Leonardo, additional, Savaris, Simone, additional, Vitola, João V., additional, Cerci, Rodrigo J., additional, Farias, Fabio R., additional, Fernandes, Miguel M., additional, Marin‐Neto, José Antonio, additional, Schmidt, André, additional, de Oliveira Lima Filho, Moysés, additional, Oliveira, Ricardo Mendes, additional, Chierice, João Reynaldo Abbud, additional, Polanczyk, Carísi A., additional, Furtado, Mariana V., additional, Smidt, Luis F., additional, Carvalho, Antonio Carlos, additional, Pucci, Gustavo, additional, Lyra, Flavio, additional, Junior, Alvaro Rabelo Alves, additional, Dracoulakis, Marianna D. A., additional, Lima, Rodolfo G. S. D, additional, Figueiredo, Estevao, additional, Caramori, Paulo Ricardo, additional, Tumelero, Rogerio, additional, Dall’Orto, Frederico, additional, Mesquita, Claudio T., additional, Colafranseschi, Alexandre S., additional, Oliveira, Amarino C., additional, Carvalho, Luiz A., additional, Palazzo, Isabella C., additional, Sousa, Andre S., additional, da Silva, Expedito Eustáquio Ribeiro, additional, de Barros, Pedro Gabriel Melo, additional, de Pádua Silva Baptista, Luciana, additional, Rodrigues, Marcelo Jamus, additional, de Resende, Marcos Valério Coimbra, additional, Saraiva, Jose Francisco, additional, Costantini, Costantino, additional, Demkow, Marcin, additional, Pracon, Radoslaw, additional, Kepka, Cezary, additional, Teresinska, Anna, additional, Kryczka, Karolina, additional, Henzel, Jan, additional, Solecki, Mateusz, additional, Kaczmarska, Edyta, additional, Mazurek, Tomasz, additional, Drozdz, Jaroslaw, additional, Czarniak, Bartosz, additional, Frach, Malgorzata, additional, Szymczyk, Konrad, additional, Niedzwiecka, Iwona, additional, Sobczak, Sebastian, additional, Ciurus, Tomasz, additional, Jakubowski, Piotr, additional, Misztal‐Teodorczyk, Magdalena, additional, Teodorczyk, Dawid, additional, Fratczak, Aleksandra, additional, Szkopiak, Marcin, additional, Lebioda, Patrycja, additional, Wlodarczyk, Michal, additional, Plachcinska, Anna, additional, Kusmierek, Jacek, additional, Miller, Magdalena, additional, Marciniak, Halina, additional, Wojtczak‐Soska, Karolina, additional, Luczak, Katarzyna, additional, Tarchalski, Tomasz, additional, Cichocka‐Radwan, Anna, additional, Szwed, Hanna, additional, Szulczyk, Grazyna Anna, additional, Witkowski, Adam, additional, Kukula, Krzysztof, additional, Celinska‐Spodar, Malgorzta, additional, Zalewska, Joanna, additional, Gajos, Grzegorz, additional, Bury, Krzysztof, additional, Pruszczyk, Piotr, additional, Roik, Marek, additional, Loboz‐Grudzien, Krystyna, additional, Sokalski, Leszek, additional, Brzezinska, Barbara, additional, Lesiak, Maciej, additional, Lanocha, Magdalena, additional, Reczuch, Krzysztof W., additional, Kalarus, Zbigniew, additional, Swiatkowski, Andrzej, additional, Szulik, Mariola, additional, Musial, Wlodzimierz J., additional, Bockeria, Leo, additional, Petrosyan, Karen, additional, Trifonova, Tatiana, additional, Chernyavskiy, Alexander M., additional, Kretov, Evgeniy I., additional, Grazhdankin, Igor O., additional, Bershtein, Leonid L., additional, Sayganov, Sergey A., additional, Kuzmina‐Krutetskaya, Anastasia M., additional, Zbyshevskaya, Elizaveta V., additional, Katamadze, Nana O., additional, Demchenko, Elena A., additional, Kozlov, Pavel S., additional, Kozulin, Vikentiy Y., additional, Lubinskaya, Ekaterina I., additional, Lopez‐Sendon, Jose, additional, Castro, Almudena, additional, Salicio, Elena Refoyo, additional, Guzman, Gabriela, additional, Galeote, Gabriel, additional, Valbuena, Silvia, additional, Peteiro, Jesús, additional, Martínez‐Ruíz, María Dolores, additional, Pérez‐Fernández, Ruth, additional, Cuenca‐Castillo, José J., additional, Flores‐Ríos, Xacobe, additional, Prada‐Delgado, Óscar, additional, Barge‐Caballero, Gonzalo, additional, Juanatey, Jose Ramon Gonzalez, additional, Bayarri, Miguel Souto, additional, Nuñez, Virginia Pubull, additional, Sanchez, Raymundo Ocaranza, additional, Alvarez, Belen Cid, additional, Gil, Carlos Peña, additional, Monzonis, Amparo Martinez, additional, Sionis, Alessandro, additional, Perales, Montserrat Vila, additional, Padró, Josep Maria, additional, Peñaranda, Antonio Serra, additional, Picart, Joan García, additional, Iglesias, Antonino Ginel, additional, Marimon, Xavier Garcia‐Moll, additional, Lladó, Guillem Pons, additional, Costa, Francesc Carreras, additional, Miro, Vicente, additional, Diez, Jose L., additional, Calvillo, Pilar, additional, Ortuño, F. Marin, additional, Chávarri, M. Valdés, additional, Montolliu, A. Tello, additional, Bermudez, E. Pinar, additional, De La Morena, G., additional, Blancas, Montserrat Gracida, additional, Luena, Jose Enrique Castillo, additional, Fernandez‐Aviles, Francisco, additional, Chen, Jiyan, additional, Wu, Yongjian, additional, Ma, Yitong, additional, Yang, Yining, additional, Ji, Zheng, additional, Yang, Xinchun, additional, Lin, Wenhua, additional, Zeng, Hesong, additional, Fu, Xin, additional, Yang, Bin, additional, Wang, Songtao, additional, Cheng, Gong, additional, Zhao, Yulan, additional, Fang, Xuehua, additional, Zeng, Qiutang, additional, Su, Xi, additional, Li, Qingxian, additional, Nie, Shao‐ping, additional, Yu, Qin, additional, Wang, Jian’an, additional, Zhang, Shuyang, additional, Liu, Zhenyu, additional, Perna, Gian Piero, additional, Marini, Marco, additional, Gabrielli, Gabriele, additional, Provasoli, Stefano, additional, Verna, Edoardo, additional, Monti, Lorenzo, additional, Nardi, Barbara, additional, Di Chiara, Antonio, additional, Mortara, Andrea, additional, Galvani, Marcello, additional, Ottani, Filippo, additional, Sicuro, Marco, additional, Calabro, Paolo, additional, Formisano, Tiziana, additional, Tarantini, Giuseppe, additional, Cucchini, Umberto, additional, Andres, Anto Luigi, additional, Racca, Emanuela, additional, Briguori, Carlo, additional, Amati, Roberto, additional, Vergoni, William, additional, Russo, Aldo, additional, Fanelli, Raffaele, additional, Poh, Kian‐Keong, additional, Chai, Ping, additional, Lau, Titus, additional, Loh, Joshua P., additional, Tay, Edgar L., additional, Teoh, Kristine, additional, Teo, Lynette L., additional, Ong, Ching‐Ching, additional, Wong, Raymond C., additional, Loh, Poay‐Huan, additional, Kofidis, Theodoros, additional, Chan, Wan Xian, additional, Chan, Koo Hui, additional, Foo, David, additional, Kong, Jason Loh Kwok, additional, Er, Ching Min, additional, Jafary, Fahim Haider, additional, Chua, Terrance, additional, Doerr, Rolf, additional, Stumpf, Juergen, additional, Matschke, Klaus, additional, Simonis, Gregor, additional, Kadalie, Clemens T., additional, Sechtem, Udo, additional, Ong, Peter, additional, Schulze, P. Christian, additional, Goebel, Bjoern, additional, Lenk, Karsten, additional, Nickenig, Georg, additional, Schuchlenz, Herwig, additional, Weikl, Stefan, additional, Lang, Irene Marthe, additional, Huber, Kurt, additional, Jakl‐Kotauschek, Gabriele, additional, Vertes, Andras, additional, Varga, Albert, additional, Fontos, Geza, additional, Merkely, Bela, additional, Kerecsen, Gabor, additional, Hinic, Sasa, additional, Zdravkovic, Marija, additional, Mudrenovic, Vladan, additional, Crnokrak, Bogdan, additional, Beleslin, Branko D., additional, Boskovic, Nikola N., additional, Petrovic, Marija T., additional, Dobric, Milan R., additional, Markovic, Zeljko Z., additional, Mladenovic, Ana S., additional, Cemerlic‐Adjic, Nada, additional, Davidovic, Goran, additional, Vucic, Rada, additional, Dekleva, Milica Nikola, additional, Stankovic, Goran, additional, Apostolovic, Svetlana, additional, Escobedo, Jorge, additional, Baleón‐Espinosa, Rubén, additional, Campos‐Santaolalla, Arturo S., additional, Durán‐Cortés, Elihú, additional, Flores‐Palacios, José M., additional, García‐Rincón, Andrés, additional, Jiménez‐Santos, Moisés, additional, Peñafiel, Joaquín V., additional, Ortega‐Ramírez, José A., additional, Valdespino‐Estrada, Aquiles, additional, Rosas, Erick Alexánderson, additional, Selvanayagam, Joseph B., additional, Joseph, Majo X., additional, Thambar, Suku T., additional, Beltrame, John F., additional, Hillis, Graham S., additional, Thuaire, Christophe, additional, Dutoiu, Téodora, additional, Steg, Philippe Gabriel, additional, Juliard, Jean‐Michel, additional, Slama, Michel S., additional, El Mahmoud, Rami, additional, Nicollet, Eric, additional, Goube, Pascal, additional, Barone‐Rochette, Gilles, additional, Furber, Alain, additional, Bière, Loïc, additional, Laucevicius, Aleksandras, additional, Celutkiene, Jelena, additional, Kedhi, Elvin, additional, Timmer, Jorik, additional, Hermanides, Rik, additional, Kaplan, Eliza, additional, Riezebos, Robert K., additional, Samadi, Pouneh, additional, van Dongen, Elise, additional, Niehe, Sander R., additional, Suryapranata, Harry, additional, van Vugt, Stijn, additional, Ramos, Ruben, additional, Cacela, Duarte, additional, Santana, Ana, additional, Fiarresga, Antonio, additional, Sousa, Lidia, additional, Marques, Hugo, additional, Patricio, Lino, additional, Bernanrdes, Luis, additional, Rio, Pedro, additional, Carvalho, Ramiro, additional, Ferreira, Rui, additional, Silva, Tiago, additional, Rodrigues, Ines, additional, Modas, Pedro, additional, Portugal, Guilherme, additional, Fragata, Jose, additional, Pinto, Fausto J., additional, Menezes, Miguel Nobre, additional, Lopes, Guilhermina Cantinho, additional, Almeida, Ana Gomes, additional, Silva, Pedro Canas, additional, Nobre, Angelo, additional, Francisco, Ana Rita, additional, Ferreira, Nuno, additional, Lopes, Ricardo L., additional, Guzman, Luis, additional, Figal, Julio César, additional, Méndiz, Oscar, additional, Cortés, Claudia, additional, Favaloro, Roberto René, additional, Alvarez, Carlos, additional, Courtis, Javier, additional, Zeballos, Gabriela, additional, Schiavi, Lilia, additional, Rubio, Mariano, additional, Devlin, Gerard Patrick, additional, Fisher, Raewyn, additional, Stewart, Ralph Alan Huston, additional, White, Harvey Douglas, additional, Benatar, Jocelyne, additional, Kedev, Sasko, additional, Mitevska, Irena Peovska, additional, Kostovska, Elizabeta Srbinovska, additional, Pejkov, Hristo, additional, Eggers, Kai, additional, Frostfelt, Gunnar, additional, Johnston, Nina, additional, Olsowka, Maciej, additional, Åkerblom, Axel, additional, Soveri, Inga, additional, Aspberg, Johannes, additional, Sharir, Tali, additional, Elian, Dan, additional, Kerner, Arthur, additional, Massalha, Samia, additional, Fukuda, Keiichi, additional, Kohsaka, Shun, additional, Yasuda, Satoshi, additional, Nishimura, Shigeyuki, additional, Van de Werf, Frans, additional, Claes, Kathleen, additional, Hung, Chung‐Lieh, additional, Yun, Chun‐Ho, additional, Hou, Charles Jia‐Yin, additional, Kuo, Jen‐Yuan, additional, Yeh, Hung‐I, additional, Hung, Ta‐Chuan, additional, Li, Jiun‐Yi, additional, Chien, Chen‐Yen, additional, Tsai, Cheng‐Ting, additional, Liu, Chun‐Chieh, additional, Yu, Fa‐Chang, additional, Lin, Yueh‐Hung, additional, Lan, Wei‐Ren, additional, Yen, Chih‐Hsuan, additional, Tsai, Jui‐Peng, additional, Sung, Kuo‐Tzu, additional, Ntsekhe, Mpiko, additional, Pandie, Shaheen, additional, Viljoen, Charle A., additional, De Andrade, Marianne, additional, Moccetti, Tiziano, additional, Rossi, M. Grazia, additional, Abdelhamid, Magdy, additional, Adel, Ahmed, additional, Kamal, Ahmed, additional, Mahrous, Hossam, additional, El Kaffas, Sameh, additional, El Fishawy, Hussien, additional, Pop, Calin, additional, Claudia, Matei, additional, Popescu, Bogdan A., additional, Ginghina, Carmen, additional, Deleanu, Dan, additional, Iliescu, Vlad A., additional, Al‐Mallah, Mouaz H., additional, Aljzeeri, Ahmed, additional, Najm, Hani, additional, Alghamdi, Ali, additional, Ramos, Walter Enrique Mogrovejo, additional, Kuanprasert, Srun, additional, Prommintikul, Arintaya, additional, Nawarawong, Weerachai, additional, Woragidpoonpol, Surin, additional, Tepsuwan, Thitipong, additional, Taksaudom, Noppon, additional, Rimsukcharoenchai, Chataroon, additional, Euathrongchit, Juntima, additional, Wannasopha, Yutthaphan, additional, Yamwong, Sukit, additional, Sritara, Piyamitr, additional, Aramcharoen, Suthara, additional, Meemuk, Krissada, additional, Khairuddin, Ahmad, additional, Hadi, Hafidz Abd, additional, and Yahaya, Shaiful Azmi, additional

Published
2024
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5. Delayed gametocyte clearance in Plasmodium vivax malaria is associated with polymorphisms in the cytochrome P450 reductase (CPR)

Author

Salazar, Yanka Evellyn Alves Rodrigues, primary, Louzada, Jaime, additional, Puça, Maria Carolina Silva de Barros, additional, Guimarães, Luiz Felipe Ferreira, additional, Vieira, José Luiz Fernandes, additional, Siqueira, André Machado de, additional, Gil, José Pedro, additional, Brito, Cristiana Ferreira Alves de, additional, and Sousa, Tais Nobrega de, additional

Published
2024
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7. Comportamentos de saúde relacionados a hipertensão arterial em idosos de uma unidade básica de saúde da cidade de Guarapuava-PR, Brasil.

Author

José Martins, Fernando, Lopes Vieira, José Luiz, José Martins, Lucas, Ferreira, Luciana, and Fiorese Vieira, Igor

Subjects
OLDER patients, OLDER people, FISHER exact test, REDUCING diets, BLOOD pressure, SMOKING cessation, TOBACCO use
Abstract

Copyright of Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación is the property of Federacion Espanola de Asociaciones de Docentes de Educacion Fisica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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10. The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis

Author

Commons, Robert J, Simpson, Julie A, Thriemer, Kamala, Humphreys, Georgina S, Abreha, Tesfay, Alemu, Sisay G, Añez, Arletta, Anstey, Nicholas M, Awab, Ghulam R, Baird, J Kevin, Barber, Bridget E, Borghini-Fuhrer, Isabelle, Chu, Cindy S, D'Alessandro, Umberto, Dahal, Prabin, Daher, André, de Vries, Peter J, Erhart, Annette, Gomes, Margarete S M, Gonzalez-Ceron, Lilia, Grigg, Matthew J, Heidari, Aliehsan, Hwang, Jimee, Kager, Piet A, Ketema, Tsige, Khan, Wasif A, Lacerda, Marcus V G, Leslie, Toby, Ley, Benedikt, Lidia, Kartini, Monteiro, Wuelton M, Nosten, Francois, Pereira, Dhelio B, Phan, Giao T, Phyo, Aung P, Rowland, Mark, Saravu, Kavitha, Sibley, Carol H, Siqueira, André M, Stepniewska, Kasia, Sutanto, Inge, Taylor, Walter R J, Thwaites, Guy, Tran, Binh Q, Tran, Hien T, Valecha, Neena, Vieira, José Luiz F, Wangchuk, Sonam, William, Timothy, Woodrow, Charles J, Zuluaga-Idarraga, Lina, Guerin, Philippe J, White, Nicholas J, and Price, Ric N

Published
2018
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13. Does resilience predict self-efficacy and motivation in dancers?

Author

Roiek Lazier Leão, Tatyanne, primary, Ferreira, Luciana, additional, Mena Leão Junior, Cleber, additional, Lucas Morais Freire, Gabriel, additional, Gomes Costa, Nathan Leonardo, additional, Andrade do Nascimento Junior, José Roberto, additional, and Lopes Vieira, José Luiz, additional

Published
2023
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18. Relationship between the sociodemographic profile and motor competence of children

Author

Ferreira, Luciana, Souza, Vânia de Fatima Matias de, Rocha, Francielli Ferreira da, Silva, Pamela Norraila da, Cheuczuk, Francielle, and Vieira, José Luiz Lopes

Subjects
Desenvolvimento Infantil, Child Development, Destreza Motora, Motor Skills, Motor Disorders, Transtornos Motores, Child, Preschool, Pré-escolar
Abstract

Resumo Objetivo Verificar as relações estabelecidas entre os fatores individuais e ambientais na competência motora de crianças de 06 a 10 anos de idade. Método Trata-se de um estudo de caráter quantitativo, sustentado na estatística descritiva e inferencial. Os seguintes instrumentos de coleta foram utilizados: Teste de Proficiência Motora de Bruininks-Oseretsky e Home Observation for Measurement of the Environment - Middle Childhood. Resultados As análises indicaram a influência dos constructos ambientais no desenvolvimento e manutenção da competência motora das crianças, elucidando o fato de que o ambiente domiciliar adequado é um fator de proteção para o desenvolvimento dessa competência. Crianças residentes em casas adequadas apresentaram em média 66% mais chances de terem competência motora. Outro fato evidenciado deu-se em razão da disparidade no nível de competência motora entre os sexos, com destaque para o fato de que meninas com idade entre 9 e 10 anos que residem em domicílios classificados como não adequados localizados na região central da cidade e que estudam em escolas públicas apresentaram valores de competência motora abaixo do esperado para sua idade. Conclusão O perfil sociodemográfico de crianças que apresentaram as melhores chances para uma proficiência motora mais alta foi de meninos com idade entre 6 e 7 anos que residem em domicílios classificados como adequados localizados em bairros e que estudam em escolas privadas. Abstract Objective To verify the relationships established between individual and environmental factors in the motor competence of children aged 06 to 10 years. Method This is a quantitative study supported by descriptive and inferential statistics. The following collection instruments were used: Bruininks-Oseretsky Motor Proficiency Test and Home Observation for Measurement of the Environment - Middle Childhood. Results The analyses indicated the influence of environmental constructs on the development and maintenance of children's motor competence, elucidating the fact that the appropriate home environment is a protective factor for the development of this competence. Children residing in adequate homes were 66% more likely to have motor competence on average. Another fact highlighted was due to the disparity in the level of motor competence between the sexes, with emphasis on the fact that girls aged 9-10 years who live in households classified as unsuitable, located in the central region of the city, studying in public schools presented motor competence values below the expected for their age. Conclusion The sociodemographic profile of children who presented the best chances for higher motor proficiency included boys aged 6-7 years old, living in households classified as adequate, located in neighborhoods outside the central region, and studying in private schools.

Published
2023

19. The haematological consequences of Plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis

Author

Commons, Robert J., Simpson, Julie A., Thriemer, Kamala, Chu, Cindy S., Douglas, Nicholas M., Abreha, Tesfay, Alemu, Sisay G., Añez, Arletta, Anstey, Nicholas M., Aseffa, Abraham, Assefa, Ashenafi, Awab, Ghulam R., Baird, J. Kevin, Barber, Bridget E., Borghini-Fuhrer, Isabelle, D’Alessandro, Umberto, Dahal, Prabin, Daher, André, de Vries, Peter J., Erhart, Annette, Gomes, Margarete S. M., Grigg, Matthew J., Hwang, Jimee, Kager, Piet A., Ketema, Tsige, Khan, Wasif A., Lacerda, Marcus V. G., Leslie, Toby, Ley, Benedikt, Lidia, Kartini, Monteiro, Wuelton M., Pereira, Dhelio B., Phan, Giao T., Phyo, Aung P., Rowland, Mark, Saravu, Kavitha, Sibley, Carol H., Siqueira, André M., Stepniewska, Kasia, Taylor, Walter R. J., Thwaites, Guy, Tran, Binh Q., Hien, Tran T., Vieira, José Luiz F., Wangchuk, Sonam, Watson, James, William, Timothy, Woodrow, Charles J., Nosten, Francois, Guerin, Philippe J., White, Nicholas J., and Price, Ric N.

Published
2019
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22. Does resilience predict self-efficacy and motivation in dancers?

Author

Lazier Leão, Tatyanne Roiek, Ferreira, Luciana, Leão Junior, Cleber Mena, Morais Freire, Gabriel Lucas, Gomes Costa, Nathan Leonardo, Andrade do Nascimento Junior, José Roberto, and Lopes Vieira, José Luiz

Subjects
SELF-efficacy, MOTIVATION (Psychology), SPORTS psychology, BALLET dancers, PSYCHOLOGICAL resilience, PEARSON correlation (Statistics)
Abstract

Copyright of Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación is the property of Federacion Espanola de Asociaciones de Docentes de Educacion Fisica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
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23. Associação entre a proficiência motora de escolares e as oportunidades de movimento oferecidas na sua vizinhança.

Author

Cheuczuk, Francielle, Ferreira da Rocha, Francielle, Norraila da Silva, Pâmela, Lopes Vieira, José Luiz, and Ferreira, Luciana

Subjects
KRUSKAL-Wallis Test, MANN Whitney U Test, SOCIOECONOMIC factors, COMPARATIVE studies, DESCRIPTIVE statistics, MOTOR ability, NEIGHBORHOOD characteristics, CHILDREN
Abstract

Copyright of Motricidade is the property of Silabas Didaticas LDA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
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24. Chloroquine resistance is associated to multi-copy pvcrt-o gene in Plasmodium vivax malaria in the Brazilian Amazon

Author

Silva, Siuhelem Rocha, Almeida, Anne Cristine Gomes, da Silva, George Allan Villarouco, Ramasawmy, Rajendranath, Lopes, Stefanie Costa Pinto, Siqueira, André Machado, Costa, Gabriel Luíz, Sousa, Taís Nóbrega, Vieira, José Luiz Fernandes, Lacerda, Marcus Vinícius Guimarães, Monteiro, Wuelton Marcelo, and de Melo, Gisely Cardoso

Published
2018
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25. Parâmetros de dificuldade e discriminação das tarefas motoras do instrumento KTK: uma análise a partir da Teoria de Resposta ao Item

Author

Nazário, Patrik Felipe, Ferreira, Luciana, Both, Jorge, and Vieira, José Luiz Lopes

Subjects
evaluation, Teoria de Resposta ao Item, Item Response Theory, coordenação motora, avaliação, motor coordination
Abstract

In the last decades, the use of Item Response Theory (IRT) has been implemented due to the complexity of statistical calculations that allows for in-depth analysis of educational tests, questionnaires and lists of items applied in different areas such as psychometry, sports ranking and pedagogy. Based on this premise, this study aimed to verify the suitability of the KTK motor tasks analyzing the degree of difficulty and discrimination parameters of each motor task. A total of 385 children aged 5 to 14 years participated in the study. The instrument evaluated was the KTK (Körperkoordinationstest für Kinder), consisting of four motor tasks: balance beam, single-pedal jumps, side jumps and platform transposition. Analyzes were conducted from the raw data acquired in each motor task. In order to verify the factor structure of the theoretical matrix underlying the test, an exploratory factor analysis was performed, followed by a confirmatory factor analysis. The difficulty and discrimination parameters of each motor task were analyzed using the gradual response model, based on the Item Response Theory (IRT). The results corroborate the factor structure suggested in the original version of the KTK, presenting only one factor, called motor coordination. The AFC indicators were acceptable, indicating good quality of the model adjusted for the sample. It is concluded that the IRT analysis evidenced differences in the parameters of difficulty and discrimination between the KTK motor tasks, demonstrating the importance of considering a weighting in the creation of normative tables of motor assessments. Nas últimas décadas o uso da Teoria de Resposta ao Item (TRI) tem sido implementada devido à complexidade dos cálculos estatísticos que permite analisar com profundidade testes educacionais, questionários e listas de itens aplicados em diferentes áreas como a psicometria, ranking esportivo e pedagogia. A partir dessa premissa este estudo teve como objetivo verificar a adequabilidade das tarefas motoras do KTK analisando o grau de dificuldade e parâmetro de discriminação de cada tarefa motora. Participaram do estudo 385 crianças de 5 a 14 anos. O instrumento avaliado foi o KTK (Körperkoordinationstest für Kinder), composto por quatro tarefas motoras: trave de equilíbrio, saltos monopedais, saltos laterais e transposição de plataformas. As análises foram conduzidas a partir dos dados brutos adquiridos em cada tarefa motora. A fim de verificar a estrutura fatorial da matriz teórica subjacente ao teste, foi realizada uma análise fatorial exploratória seguida da análise fatorial confirmatória. Os parâmetros de dificuldade e discriminação de cada tarefa motora foram analisados a partir do modelo de resposta gradual, fundamentado na teoria de resposta ao item (TRI). Os resultados corroboram com a estrutura fatorial sugerida na versão original do KTK, apresentando apenas um fator, chamado de coordenação motora. Os indicadores da Análise Fatorial Confirmatória (AFC) foram aceitáveis, indicando boa qualidade do modelo ajustado para a amostra. Conclui-se que a análise de TRI evidenciou diferenças nos parâmetros de dificuldade e de discriminação entre as tarefas motoras do KTK, demonstrando a importância de considerar uma ponderação na criação de tabelas normativas de avaliações motoras.

Published
2022

27. MOVEMENT ASSESSMENT BATTERY FOR CHILDREN-SECOND EDITION: THEORETICAL ADEQUACY OF A MOTOR ASSESSMENT INSTRUMENT

Author

Nazario, Patrik Felipe, Ferreira, Luciana, Both, Jorge, and Vieira, José Luiz Lopes

Subjects
Criança, pré-escolar, Male, Educational measurement, Psychometrics, Child, preschool, 030309 nutrition & dietetics, Explanatory model, Applied psychology, Motor activity, Pediatrics, Movement assessment, RJ1-570, Avaliação educacional, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, Humans, Dimension (data warehouse), Child, Balance (ability), 0303 health sciences, Reproducibility of Results, Exploratory factor analysis, Confirmatory factor analysis, Motor Skills Disorders, Atividade motora, Pediatrics, Perinatology and Child Health, Exercise Test, Original Article, Female, Psicometria, Factor Analysis, Statistical, Psychology, Brazil
Abstract

Objective: To investigate the adequacy of the theoretical model of the Movement Assessment Battery for Children-Second Edition (MABC-2) instrument. Methods: 582 children, of both sexes, aged between 3 and 5 years and residents in the city of Maringá (state of Paraná, Southern Brazil) participated in the study. Data were collected from May/2014 to June/2015 and analyzed using descriptive and inferential statistics. Results: The evidence obtained from exploratory factor analysis indicated the presence of two factors, which was the option that best fitted the explanatory model. Hence, it was necessary to regroup the motor tasks of the dimensions “Aiming & catching” and “Balance” into only one dimension. It is noteworthy that the “Bicycle trail” motor task did not fit the model, as it presented a low and negative factor load in the analyzed dimensions. In the confirmatory factor analysis, adequate adjustment indices were observed for the tested model, which confirmed the non-classification of the “Bicycle trail” motor task in the original dimension. Conclusions: After removing the “Bicycle trail” motor task, the adjusted two-factor model seems to be the most appropriate to assess the motor performance of children participating in the study. RESUMO Objetivo: Investigar a adequabilidade do modelo teórico do instrumento de avaliação motora Movement Assessment Battery for Children-Second Edition. Métodos: Participaram do estudo 582 crianças, de ambos os sexos com idade entre 3 e 5 anos da cidade de Maringá, Paraná, no período de maio/2014 a junho/2015. Para analisar os dados, utilizou-se a estatística descritiva e inferencial. Resultados: As evidências obtidas por meio da análise fatorial exploratória indicaram a presença de dois fatores. Essa opção foi a que melhor se ajustou ao modelo explicativo. Com isso, foi necessário reagrupar as tarefas motoras das dimensões “lançar e receber” e “equilíbrio” em apenas uma dimensão. Destaca-se que a tarefa motora “caminho da bicicleta” não se adequou ao modelo, pois apresentou carga fatorial baixa e negativa nas dimensões analisadas. Na análise fatorial confirmatória, observaram-se índices de ajustamento adequados para o modelo testado, a qual confirmou o não enquadramento da tarefa motora “caminho da bicicleta” na dimensão original. Conclusões: Após a retirada da tarefa motora “caminho da bicicleta”, o modelo ajustado de dois fatores parece ser o mais adequado para avaliar o desempenho motor das crianças participantes do estudo.

Published
2022

29. PARÂMETROS DE DIFICULDADE E DISCRIMINAÇÃO DAS TAREFAS MOTORAS DO INSTRUMENTO KTK: UMA ANÁLISE A PARTIR DA TEORIA DE RESPOSTA AO ITEM.

Author

Nazário, Patrik Felipe, Ferreira, Luciana, Both, Jorge, and Lopes Vieira, José Luiz

Subjects
ITEM response theory, EXPLORATORY factor analysis, CONFIRMATORY factor analysis, PSYCHOMETRICS, MOTOR ability
Abstract

Copyright of Journal of Physical Education (24482455) is the property of Universidade Estadual de Maringa and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
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30. Influence of sex on the exposure to isoniazid in patients with pulmonary tuberculosis.

Author

Bardalez Rivera, Juan Gonzalo, Abreu Albério, Carlos Augusto, and Fernandes Vieira, José Luiz

Subjects
TUBERCULOSIS, ISONIAZID, DRUG monitoring, TUBERCULOSIS patients, HIGH performance liquid chromatography, ANTITUBERCULAR agents
Abstract

Isoniazid is a key component of tuberculosis treatment. Adequate exposure is a determinant for therapeutic success; however, considerable inter- and intraindividual variations in drug plasma levels can lead to unfavorable outcomes. While some predictors of isoniazid levels are well-known, others, such as sex, yield controversial results, requiring further investigation to optimize exposure. This study investigates whether the sex of patients influences the dose administered and the concentrations of isoniazid in plasma. Levels of isoniazid were associated with the N-acetyltransferase 2 phenotypes. A total of 76 male and 58 female patients were included. Isoniazid was measured by high-performance liquid chromatography, and N-acetyltransferase 2 phenotypes were assessed using molecular techniques. The results show that the dose administered, expressed in mg/kg, was higher in females, but the plasma levels were similar between both sexes. Among patients, 46.2%, 38.8%, and 15% were slow, intermediate, and fast acetylators, respectively. As expected, isoniazid levels were associated with the acetylation phenotypes, with higher concentrations in the slow acetylators. Thus, sex-related difference in isoniazid levels is due to the body weight of patients, and the optimized dose regimen based on patient weight and acetylator phenotypes can improve the treatment outcomes. [ABSTRACT FROM AUTHOR]

Published
2023
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35. COMPARAÇÃO DO DESEMPENHO MOTOR DE CRIANÇAS ENTRE ESCOLAS PÚBLICAS DE TEMPO PARCIAL E INTEGRAL

Author

Bim, Ricardo Henrique and Vieira, José Luiz Lopes

Subjects
Escola de tempo integral, Crianças, Destreza Motora
Abstract

O ensino em tempo integral vem sendo implantado gradativamente nas escolas públicas brasileiras nas últimas décadas. O objetivo deste estudo foi comparar o desempenho motor de crianças matriculadas em escolas públicas de tempo parcial e integral. Foram avaliadas 159 crianças, com idades entre 7 e 8 anos, sendo 75 (47,2%) do sexo feminino e 84 (52,8%) do sexo masculino, das quais 77 (48,4%) estavam matriculadas no ensino parcial e 82 (51,6%) no ensino integral, todas no 3º. ano do ensino fundamental de quatro escolas públicas municipais na cidade de Maringá-PR. O Test of Gross Motor Development-2 (TGMD-2) foi utilizado como instrumento de medida para avaliar o desempenho motor das crianças. Para análise dos dados quantitativos foi utilizada estatística descritiva, o teste de normalidade Kolgomorov-Smirnov, e o Teste U de Mann Whitney para as comparações das variáveis de desempenho motor. Adotou-se nível de significância de P

Published
2021
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36. Acompanhamento longitudinal das alterações no transtorno do desenvolvimento da coordenação em crianças pré-escolares/ Longitudinal study changes in coordination development disorder in preschool children

Author

Santos, Viviane Aparecida Pereira dos, Ferreira, Luciana, Both, Jorge, Caruzzo, Nayara Malheiro, and Vieira, José Luiz Lopes

Abstract

Objetivo: Acompanhar, ao longo de 24 meses, as alterações entre o diagnóstico de Desenvolvimento Motor Típico (DM) e o provável Transtorno do Desenvolvimento da Coordenação (pTDC) em pré-escolares. Método: Foram elaborados dois designs de coleta: 1) Design longitudinal de 12 meses (Long-1), constituído por 201 crianças, com idade inicial média de 3,6±0,5 anos; 2) Design longitudinal de 24 meses (Long-2), composto por 27 crianças, com idade inicial média de 3,6±0,1 anos. Como instrumento de avaliação, foi utilizado o Movement Assessment Battery for Children 2 (MABC-2). Os dados foram analisados usando os testes Kolmogorov-Smirnov, Shapiro-Wilk, Wilcoxon e Friedman, adotando p

Published
2021

37. Transtorno do Desenvolvimento da Coordenação: desconhecido por pais e professores.

Author

Pereira dos Santos, Viviane Aparecida, Lopes Vieira, José Luiz, de Fátima Matias de Souza, Vânia, and Ferreira, Luciana

Subjects
APRAXIA, PERCEPTUAL disorders, MOTOR ability, PARENT-teacher relationships, MOVEMENT disorders, MANN Whitney U Test
Abstract

Copyright of Ensaio: Avaliação e Políticas Públicas em Educação is the property of Ensaio: Avaliacao e Politicas Publicas em Educacao and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022
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40. Longitudinal study changes in coordination development disorder in preschool children

Author

Santos, Viviane Aparecida Pereira dos, Ferreira, Luciana, Both, Jorge, Caruzzo, Nayara Malheiros, and Vieira, José Luiz Lopes

Subjects
Desenvolvimento Infantil, Child Development, Destreza Motora, Motor Skills, Motor Disorders, Transtornos Motores, Preschool, Pré-escolar
Abstract

Resumo Objetivo Acompanhar, ao longo de 24 meses, as alterações entre o diagnóstico de Desenvolvimento Motor Típico (DM) e o provável Transtorno do Desenvolvimento da Coordenação (pTDC) em pré-escolares. Método Foram elaborados dois designs de coleta: 1) Design longitudinal de 12 meses (Long-1), constituído por 201 crianças, com idade inicial média de 3,6±0,5 anos; 2) Design longitudinal de 24 meses (Long-2), composto por 27 crianças, com idade inicial média de 3,6±0,1 anos. Como instrumento de avaliação, foi utilizado o Movement Assessment Battery for Children 2 (MABC-2). Os dados foram analisados usando os testes Kolmogorov-Smirnov, Shapiro-Wilk, Wilcoxon e Friedman, adotando p

Published
2020

43. Associação entre desempenho motor, maturidade cognitiva e aspectos sociodemográficos em crianças pré-escolares

Author

Caruzzo, Nayara Malheiros, Santos, Viviane Aparecida Pereira dos, Belem, Isabella Caroline, Contreira, Andressa Ribeiro, Fiorese, Lenamar, and Vieira, José Luiz Lopes

Subjects
pré-escolar, Motor skills, desenvolvimento infantil, Destreza motora, destreza motora, lcsh:L, Child development, Child preschool, Desenvolvimento infantil, Pré-escolar, lcsh:Education
Abstract

RESUMO A identificação da baixa proficiência motora em crianças na idade pré-escolar permite que programas de intervenção sejam propostos, para minimizar os prejuízos nas atividades escolares, relações sociais e aulas de Educação Física. Dessa forma, identificar os fatores subjacentes ao baixo desempenho motor é fundamental, na tentativa de reduzir possíveis desordens motoras. Objetivou-se investigar a associação entre desempenho motor, maturidade cognitiva e aspectos sociodemográficos em crianças pré-escolares paranaenses. Participaram 357 pré-escolares de 3,5 a 5 anos. Foram utilizados: Escala de Maturidade Mental Colúmbia, teste Movement Assessment Battery for Children - 2 e uma ficha de dados sociodemográficos. Análise estatística: teste Kolmogorov-Smirnov, Friedman (Wilcoxon) e Regressão logística binária (pR$1.500,00 (45,5%). Observou-se associação significativa entre MC superior e baixa proficiência motora, indicando a MC superior como um fator de proteção (OR 0,513 IC 95% 0,266-1,000). Os fatores sociodemográficos não se mostraram intervenientes no desempenho motor (DM). Concluiu-se que a MC superior em crianças na primeira infância atua como fator de proteção à baixa proficiência motora e que os fatores sociodemográficos da família não se associaram ao DM e a MC dos pré-escolares. ABSTRACT The identification of low motor proficiency in children of preschool age allows intervention programs to be proposed, to minimize the losses in school activities, social relationships and Physical Education classes. Thus, identifying the factors underlying low motor performance is essential, in an attempt to reduce possible motor disorders. The objective of this study was to investigate the association between motor performance, cognitive maturity and sociodemographic aspects in preschool children from Paraná. The participants were 357 preschoolers from 3,5 years to 5 years. The Columbia Mental Maturity Scale, Movement Assessment Battery for Children-2 test and a sociodemographic data sheet were used. For statistical analysis, the Kolmogorov-Smirnov, Friedman (Wilcoxon) and binary logistic regression tests (pR$1,500, 00 (45.5%). A significant association was observed between higher CM and low motor proficiency, indicating the upper CM as a protective factor for low motor proficiency (OR 0.513 IC 95% 0,266-1,000). The socio-demographic factors were not intervening in the motor performance (MP). It was concluded that the upper CM in children in early childhood acts as a protective factor for the low motor proficiency and that the socio-demographic factors of the family were not associated with MP and the CM of the preschoolers.

Published
2020

44. Coach-athlete relationship and collective efficacy in volleyball: is the association explained by athletes’ goal orientations?

Author

Nascimento Junior, José Roberto Andrade do, Fiorese, Lenamar, Vieira, José Luiz Lopes, Ferreira, Luciana, Cheuczuk, Francielle, Jowett, Sophia, Fortes, Leonardo de Sousa, and Vissoci, João Ricardo Nickenig

Subjects
human activities
Abstract

The mediating role of goal orientations in the association between coach-athlete relationship (CAR) and collective efficacy (CE) was investigated. Participants were 185 Brazilian young volleyball players participants of a State championship. Data were obtained using the Coach-Athlete Relationship Questionnaire, Task and Ego Orientation in Sport Questionnaire and Collective Efficacy Questionnaire for Sports. Structural Equation Modeling revealed CAR had a moderate effect on task orientation. Task orientation was associated with CE. CAR had a positive effect on ego orientation. Ego orientation was not associated with CE. When the association between CAR and CE was mediated by task orientation, the relationship explained 27% of the CE variance. The results suggest that a good quality CAR allows athletes to be more focused on their goals and individual skill development, and, consequently, this type of focus allows the team to perform more effectively., Motricidade, vol. 15 n.º 2-3 (2019): Motricidade

Published
2020
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45. Relação da força de preensão manual, a competência motora e a qualidade da escrita de crianças em processo de aprendizagem e escrita

Author

Ardengue, Mariana, Ferreira, Luciana, Nunhes, Pollyana Mayara, Vieira, José Luiz Lopes, and Avelar, Ademar

Subjects
Desenvolvimento infantil. Destreza motora. Escrita manual
Abstract

O objetivo do estudo foi verificar a influência da força de preensão manual (FPM) na competência motora (CM) e qualidade da escrita (QE) de crianças em processo de aprendizagem da escrita. Participaram do estudo 61 escolares de 05 a 07 anos matriculadas no primeiro ano escolar. Para mensurar FPM utilizou-se um dinamômetro de mão e para avaliar a CM utilizou-se o teste de Bruininks-Oseretsky Test of Motor Proficiency, Second Edition BOT-2 nas dimensões Precisão Motora Fina (PMF), Integração Motora Fina (IMF), Destreza manual (DM) e Coordenação Bilateral (CB). A avaliação da QE foi feita pelos professores. Para a análise estatística utilizou-se ANOVA one-way para comparar a CM e QE de acordo com a FPM. ANOVA two-way para comparar a CM e QE de acordo com a FPM e sexo. De forma geral, a FPM mostrou-se maior (p

Published
2019

46. An Ultra-Sensitive Technique: Using Pv-mtCOX1 qPCR to Detect Early Recurrences of Plasmodium vivax in Patients in the Brazilian Amazon

Author

Barbosa, Laila R. A., primary, da Silva, Emanuelle L., additional, de Almeida, Anne C. G., additional, Salazar, Yanka E. A. R., additional, Siqueira, André M., additional, Alecrim, Maria das Graças Costa, additional, Vieira, José Luiz Fernandes, additional, Bassat, Quique, additional, de Lacerda, Marcus V. G., additional, Monteiro, Wuelton M., additional, and Melo, Gisely C., additional

Published
2020
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50. PARÂMETROS DE DIFICULDADE E DISCRIMINAÇÃO DAS TAREFAS MOTORAS DO INSTRUMENTO KTK: UMA ANÁLISE A PARTIR DA TEORIA DE RESPOSTA AO ITEM.

Author

Felipe Nazário, Patrik, Ferreira, Luciana, Both, Jorge, and Lopes Vieira, José Luiz

Subjects
ITEM response theory, EXPLORATORY factor analysis, CONFIRMATORY factor analysis, PSYCHOMETRICS, MOTOR ability
Abstract

Copyright of Journal of Physical Education (24482455) is the property of Universidade Estadual de Maringa and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022
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