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Subclinical Hypothyroidism is a clinical syndrome which result from the deficiency of Thyroid hormones. Usually, it runs a chronic course with slow and insidious onset. Sometimes it is only accidentally diagnosed. Thyroid gland abnormality where, on one hand influences body metabolism up to a great extent, on the other hand, it is found more in females with ratio of male to female being 1:6, if left untreated it can lead to severe complication. In Ayurveda there is no direct comparison regarding symptoms of Subclinical Hypothyroidism but on the basis of clinical presentation it can be correlated with different entities as syndrome, so it is difficult to give a single Ayurvedic term for it, as there are many systems which are involved in the pathogenesis of Subclinical Hypothyroidism. Hence the symptoms of Pre-clinical and post clinical findings are compared with Rasapradoshaja Vikaras.

The effect of Gandharva Haritaki, Sudarshana Vati, Arogyavardhini Vati along with Punarnavadi Kashaya were studied clinically on a case of Hepatits - C by modern diagnostic tools with USG Abdomen and Hematological investigations. The review of the patient was done on daily basis in IPD and weekly basis after discharge, the clinical features like loss of appetite, heaviness of abdomen and general weakness were completely subsided during the 2nd month of treatment.