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Your search keyword '"Vidgren, Gabriele"' showing total 14 results
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14 results on '"Vidgren, Gabriele"'

1. Type 2 Diabetes: Evidence for Linkage on Chromosome 20 in 716 Finnish Affected Sib Pairs

Author

Ghosh, Soumitra, Watanabe, Richard M., Hauser, Elizabeth R., Valle, Timo, Magnuson, Victoria L., Erdos, Michael R., Langefeld, Carl D., Balow,, James, Ally, Delphine S., Kohtamaki, Kimmo, Chines, Peter, Birznieks, Gunther, Kaleta, Hong-Shi, Musick, Anjene, Te, Catherine, Tannenbaum, Joyce, Eldridge, William, Shapiro, Shane, Martin, Colin, Witt, Alyson, So, Alistair, Chang, Jennie, Shurtleff, Ben, Porter, Rachel, Kudelko, Kristina, Unni, Arun, Segal, Leonid, Sharaf, Ravi, Blaschak-Harvan, Jillian, Eriksson, Johan, Tenkula, Tuula, Vidgren, Gabriele, Ehnholm, Christian, Tuomilehto-Wolf, Eva, Hagopian, William, Buchanan, Thomas A., Tuomilehto, Jaakko, Bergman, Richard N., Collins, Francis S., and Boehnke, Michael

Published
1999

3. S-layer protein gene of Lactobacillus brevis: cloning by polymerase chain reaction and determination of the nucleotide sequence

Author

Vidgren, Gabriele, Palva, Ilkka, Pakkanen, Raimo, Lounatmaa, Kari, and Palva, Airi

Subjects
Plasma membranes -- Research, Lactobacillus -- Genetic aspects, Polymerase chain reaction -- Usage, Biological sciences
Abstract

The gene encoding the surface (S)-layer protein of Lactobacillus brevis was analyzed. Immunoelectron microscopy confirmed that a 46-kDa protein corresponds to the S-layer protein of L. brevis and that it is located in the outermost part of the cell wall. Sequencing of the S-layer gene region was then performed from polymerase chain reaction fragments. The gene has the capacity to encode a protein of 48,159 Da. Removal of the putative 30-amino-acid signal peptide results in a polypeptide of 435 amino acids with a calculated molecular mass of 45 kDa. Moreover, Northern blot analysis confirmed the monocistronic nature of the S-layer operon.

Published
1992

4. A Large Sample of Finnish Diabetic Sib-Pairs Reveals No Evidence for a Non-Insulin-dependent Diabetes Mellitus Susceptibility Locus at 2qter

Author

Ghosh, Soumitra, Hauser, Elizabeth R., Magnuson, Victoria L., Valle, Timo, Ally, Delphine S., Karanjawala, Zarir E., Rayman, Joseph B., Knapp, Julie I., Musick, Anjene, Tannenbaum, Joyce, Te, Catherine, Eldridge, William, Shapiro, Shane, Musick, Tiffany, Martin, Colin, So, Alistair, Witt, Alyson, Harvan, Jillian Blaschak, Watanabe, Richard M., Hagopian, William, Eriksson, Johan, Nylund, Stella J., Kohtamaki, Kimmo, Tuomilehto-Wolf, Eva, Toivanen, Liisa, Vidgren, Gabriele, Ehnholm, Christian, Bergman, Richard N., Tuomilehto, Jaakko, Collins, Francis S., and Boehnke, Michael

Published
1998

5. Mapping Genes for NIDDM: Design of the Finland-United States Investigation of NIDDM Genetics (FUSION) Study

Author

Valle, Timo, Tuomilehto, Jaakko, Bergman, Richard N., Ghosh, Soumitra, Hauser, Elizabeth R., Eriksson, Johan, Nylund, Stella J., Kohtamaki, Kimmo, Toivanen, Liisa, Vidgren, Gabriele, Tuomilehto-Wolf, Eva, Ehnholm, Christian, Blaschak, Jillian, Langefeld, Carl D., Watanabe, Richard M., Magnuson, Victoria, Ally, Delphine S., Hagopian, William A., Ross, Edna, Buchanan, Thomas A., Collins, Francis, and Boehnke, Michael

Published
1998

7. The Finland--United States Investigation of Non--Insulin-Dependent Diabetes Mellitus Genetics (FUSION) Study. II. An Autosomal Genome Scan for Diabetes-Related Quantitative-Trait Loci

Author

Watanabe, Richard M., Ghosh, Soumitra, Langefeld, Carl D., Valle, Timo T., Hauser, Elizabeth R., Magnuson, Victoria L., Mohlke, Karen L., Silander, Kaisa, Ally, Delphine S., Chines, Peter, Blaschak-Harvan, Jillian, Douglas, Julie A., Duren, William L., Epstein, Michael P., Fingerlin, Tasha E., Kaleta, Hong Shi, Lange, Ethan M., Li, Chun, McEachin, Richard C., Stringham, Heather M., Trager, Edward, White, Peggy P., Balow, James Jr., Birznieks, Gunther, Chang, Jennie, Eldridge, William, Erdos, Michael R., Karanjawala, Zarir E., Knapp, Julie I., Kudelko, Kristina, Martin, Colin, Morales-Mena, Anabelle, Musick, Anjene, Musick, Tiffany, Pfahl, Carrie, Porter, Rachel, Rayman, Joseph B., Rha, David, Segal, Leonid, Shapiro, Shane, Sharaf, Ravi, Shurtleff, Ben, So, Alistair, Tannenbaum, Joyce, Te, Catherine, Tovar, Jason, Unni, Arun, Welch, Christian, Whiten, Ray, Witt, Alyson, Kohtamaki, Kimmo, Ehnholm, Christian, Eriksson, Johan, Toivanen, Liisa, Vidgren, Gabriele, Nylund, Stella J., Tuomilehto-Wolf, Eva, Ross, Edna H., Demirchyan, Elza, Hagopian, William A., Buchanan, Thomas A., Tuomilehto, Jaakko, Bergman, Richard N., Collins, Francis, and Boehnke, Michael

Subjects
Genetic research -- Analysis, Human genetics -- Research, Genetic disorders -- Research, Diabetes -- Genetic aspects, Biological sciences
Published
2000

8. The Finland--United States Investigation of Non--Insulin-Dependent Diabetes Mellitus Genetics (FUSION) Study. I. An Autosomal Genome Scan for Genes That Predispose to Type 2 Diabetes

Author

Ghosh, Soumitra, Watanabe, Richard M., Valle, Timo T., Hauser, Elizabeth R., Magnuson, Victoria L., Langefeld, Carl D., Ally, Delphine S., Mohlke, Karen L., Silander, Kaisa, Kohtamaki, Kimmo, Chines, Peter, Balow, James Jr., Birznieks, Gunther, Chang, Jennie, Eldridge, William, Erdos, Michael R., Karanjawala, Zarir E., Knapp, Julie I., Kudelko, Kristina, Martin, Colin, Morales-Mena, Anabelle, Musick, Anjene, Musick, Tiffany, Pfahl, Carrie, Porter, Rachel, Rayman, Joseph B., Rha, David, Segal, Leonid, Shapiro, Shane, Sharaf, Ravi, Shurtleff, Ben, So, Alistair, Tannenbaum, Joyce, Te, Catherine, Tovar, Jason, Unni, Arun, Welch, Christian, Whiten, Ray, Witt, Alyson, Blaschak-Harvan, Jillian, Douglas, Julie A., Duren, William L., Epstein, Michael P., Fingerlin, Tasha E., Kaleta, Hong Shi, Lange, Ethan M., Li, Chun, McEachin, Richard C., Stringham, Heather M., Trager, Edward, White, Peggy P., Eriksson, Johan, Toivanen, Liisa, Vidgren, Gabriele, Nylund, Stella J., Tuomilehto-Wolf, Eva, Ross, Edna H., Demirchyan, Elza, Hagopian, William A., Buchanan, Thomas A., Tuomilehto, Jaakko, Bergman, Richard N., Collins, Francis, and Boehnke, Michael

Subjects
Genetic research -- Analysis, Human genetics -- Research, Genetic disorders -- Research, Diabetes -- Genetic aspects, Biological sciences
Published
2000

13. Wild fish are negligible transmitters of viral haemorrhagic septicaemia virus (VHSV) genotype Id in the VHS restriction zone in Finland.

Author

Vennerström P, Välimäki E, Hautaniemi M, Lyytikäinen T, Kapiainen S, Vidgren G, and Virtala AM

Subjects
Animals, Finland, Genotype, Hemorrhagic Septicemia, Viral, Novirhabdovirus, Oncorhynchus mykiss
Abstract

Wild fish were suspected to be the source of reinfection by viral haemorrhagic septicaemia virus (VHSV) in Finnish brackish water rainbow trout farms located in a restriction zone regarding viral haemorrhagic septicaemia (VHS) comprising the entire Province of Åland, Baltic Sea, in the 2000s. Altogether, 1636 wild fish of 17 different species living in the vicinity of infected fish farms were screened for VHSV during the years 2005-2008. Additionally, 2 uninfected wild fish species as well as farmed whitefish were introduced into a VHS-positive fish farm to test whether they became infected by VHSV from the clinically diseased rainbow trout. Wild fish did not test positive for VHSV on any occasion. In contrast, whitefish introduced to a VHS-positive farm were infected with VHSV genotype Id and started to replicate the virus for a short time during the trial. Whitefish are farmed together with, or in the vicinity of, farmed rainbow trout in the study area and, according to this study, are a possible source of the recurring infection in the restriction area. A sprivivirus was isolated from all fish species in the infection trial without causing mortality in the test groups.

Published
2018
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14. Viral haemorrhagic septicaemia virus (VHSV Id) infections are detected more consistently using syndromic vs. active surveillance.

Author

Vennerström P, Välimäki E, Lyytikäinen T, Hautaniemi M, Vidgren G, Koski P, and Virtala AM

Subjects
Animals, Antibodies, Viral blood, Aquaculture, Finland epidemiology, Hemorrhagic Septicemia, Viral epidemiology, Oncorhynchus mykiss blood, Population Surveillance, Hemorrhagic Septicemia, Viral diagnosis, Novirhabdovirus isolation & purification, Oncorhynchus mykiss virology
Abstract

The eradication of viral haemorrhagic septicaemia virus (VHSV Id) from Finnish brackish-water rainbow trout Oncorhynchus mykiss farms located in the restriction zone in the Province of Åland, Baltic Sea, failed several times in the 2000s. The official surveillance programme was often unable to find VHSV-positive populations, leading to the misbelief in the fish farming industry that virus eradication could be achieved. The ability of 3 other surveillance programmes to detect infected fish populations was compared with the official programme. One programme involved syndromic surveillance based on the observation of clinical disease signs by fish farmers, while 2 programmes comprised active surveillance similar to the official programme, but included increased sampling frequencies and 2 additional tests. The syndromic surveillance concentrated on sending in samples for analysis when any sign of a possible infectious disease at water temperatures below 15°C was noticed. This programme clearly outperformed active surveillance. A real-time reverse transcriptase-polymerase chain reaction method proved to be at least as sensitive as virus isolation in cell culture in detecting acute VHSV infections. An ELISA method was used to test fish serum for antibodies against VHSV. The ELISA method may be a useful tool in VHSV eradication for screening populations during the follow-up period, before declaring an area free of infection.

Published
2017
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