178 results on '"Vida, Vl"'
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2. Club 35 Poster Session Wednesday 11 December: 11/12/2013, 09: 30–16: 00Location: Poster area
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Castaldi, B, Vida, VL, Guariento, A, Padalino, M, Cerutti, A, Maschietto, N, Biffanti, R, Reffo, E, Stellin, G, and Milanesi, O
- Published
- 2013
3. Pulmonary Valve Preservation During Tetralogy of Fallot Repair is Associated With Enhanced Pulmonary Valve and Right Ventricular Function
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Guariento, A, Avesani, M, Schiena, Ca, Doulamis, Ip, Padalino, Ma, Castaldi, B, Di Salvo, G, and Vida, Vl
- Published
- 2020
4. Natural history and clinical outcome of 'uncorrected' scimitar syndrome patients: a multicenter study of the italian society of pediatric cardiology
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Vida VL, Padrini M, Boccuzzo G, Agnoletti G, Bondanza S, Butera G, Chiappa E, Marasini M, Pilati M, Pongiglione G, Prandstraller D, RUSSO, Maria Giovanna, Castaldi B, Santoro G, Spadoni I, Stellin G, Milanesi O., Vida, Vl, Padrini, M, Boccuzzo, G, Agnoletti, G, Bondanza, S, Butera, G, Chiappa, E, Marasini, M, Pilati, M, Pongiglione, G, Prandstraller, D, Russo, Maria Giovanna, Castaldi, B, Santoro, G, Spadoni, I, Stellin, G, and Milanesi, O.
- Published
- 2014
5. Pulmonary artery branch stenosis in patients with congenital heart disease
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Vida, Vl, Rito, Ml, Zucchetta, F, Biffanti, R, Padalino, Ma, Milanesi, Ornella, and Stellin, Giovanni
- Subjects
Male ,Reoperation ,Time Factors ,Heart Diseases ,Infant, Newborn ,Infant ,Constriction, Pathologic ,Pulmonary Artery ,Treatment Outcome ,Recurrence ,Child, Preschool ,Humans ,Female ,Stents ,Child ,Vascular Surgical Procedures ,Follow-Up Studies - Abstract
We sought to evaluate our recent experience with surgical treatment of branch pulmonary artery (PA) stenosis both for native and acquired lesions.The postoperative course of patients who underwent surgical PA plasty augmentation between January 2004 and January 2012 were reviewed. Primary outcomes included the need for further surgical procedures or interventional maneuvers on the branch PAs for residual stenosis.Thirty-four patients were included. Median age at PA plasty was eight months (range 8 days to 3.4 years). There were 12 native and 22 acquired PA stenoses, which were mainly located at the PA branch origin (n = 25, 73%). The PA plasty was defined as simple (n = 16, 47%) and as complex (n = 18, 53%), which included multiple maneuvers on the PA branches. Median follow-up time after surgical treatment was 4.7 years (range 0.9 to 8.7 years). One patient died 3 days after complex PA plasty for low output syndrome and another died 22 months later for congestive heart failure. Twenty-one (63.6%) underwent 40 catheter intervention procedures on the PA branches for residual stenosis. The majority of them (n = 10, 57.1%) were operated before the age of six months and the majority had an acquired PA stenosis (14, 66.7%). Three patients underwent additional surgical maneuvers on the PA branches.PA branch stenosis represents a life-threatening condition often necessitating further surgical or interventional treatment. A combined collaborative surgical followed by transcatheter approach is important, particularly in cases with an acquired PA stenosis who require complex surgical repair.
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- 2013
6. European Congenital Heart Surgeons Association (ECHSA). Pediatric Coronary Artery Revascularization: A European Multicenter Study
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Vida, Vl, Torregrossa, G, De Franceschi, M, Padalino, M, Belli, E, Berggren, H, Ciçek, S, Ebels, T, Fragata, J, Hoel, Tn, Horer, J, Hraska, V, Kostolny, M, Lindberg, H, Mueller, C, Pretre, R, Rosser, B, Rubay, J, Schreiber, C, Speggiorin, S, Tlaskal, T, and Stellin, G
- Published
- 2013
7. Left ventricular/biventricular assist device support in children with the Berlin Heart EXCOR: earlier indication is mandatory
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Bortolami, A., Massimo Padalino, Gambino, A., Toscano, G., Feltrin, G., Vida, Vl, Stellin, G., and Gerosa, G.
- Published
- 2012
8. Surgical ligation of cisterna chyli: an alternative treatment for chronic chylothorax in children.Ann Thorac Surg. 2010 Nov;90(5):1732-4
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Zanin, A, Padalino, Ma, Cerutti, A, Vida, Vl, Milanesi, Ornella, Stellin, Giovanni, Bardini, R, and Nov, ANN THORAC S. U. R. G.
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- 2010
9. The Scimitar Syndrome: An European Multicentric Study
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Vida, Vl, Speggiorin, Simone, Padalino, Ma, Boccuzzo, Giovanna, and Stellin, Giovanni
- Published
- 2009
10. Natural and unnatural history of pulmonary valve stenosis
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Maschietto, N, Tessarotto, L, Biffanti, R, Salvadori, S, Padalino, Am, Vida, Vl, Stellin, Giovanni, and Milanesi, Ornella
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- 2006
11. Should we attempt functional univentricular or partial biventricular repair for patients with complex congenital cardiac anomalies and hypoplasia of the subpulmonarhy ventricle?
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Vida, Vl, Rubino, M, Bottio, Tomaso, Milanesi, Ornella, Pittarello, G, and Stellin, Giovanni
- Published
- 2004
12. Surgery for primary cardiac tumors in children: early and late results in a multicenter European congenital heart surgeons association study.
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Padalino MA, Vida VL, Boccuzzo G, Tonello M, Sarris GE, Berggren H, Comas JV, Di Carlo D, Di Donato RM, Ebels T, Hraska V, Jacobs JP, Gaynor JW, Metras D, Pretre R, Pozzi M, Rubay J, Sairanen H, Schreiber C, and Maruszewski B
- Abstract
BACKGROUND: To evaluate indications and results of surgery for primary cardiac tumors in children. METHODS AND RESULTS: Eighty-nine patients aged <=18 years undergoing surgery for cardiac tumor between 1990 and 2005 from 16 centers were included retrospectively (M/F=41/48; median age 4.3 months, range 1 day to 18 years). Sixty-three patients (68.5%) presented with symptoms. Surgery consisted of complete resection in 62 (69.7%) patients, partial resection in 21 (23.6%), and cardiac transplant in 4 (4.5%). Most frequent histotypes (93.2%) were benign (rhabdomyoma, myxoma, teratoma, fibroma, and hemangioma). Postoperative complications occurred in 29.9%. Early and late mortality were 4.5% each (mean follow-up, 6.3±4.4 years); major adverse events occurred in 28.2% of the patients; 90.7% of patients are in New York Heart Association class I. There were no statistically significant differences in survival, postoperative complications, or adverse events after complete and partial resection in benign tumors other than myxomas. Cardiac transplant was associated significantly with higher mortality rate (P=0.006). Overall mortality was associated to malignancy (P=0.0008), and adverse events during follow-up (P=0.005). CONCLUSIONS: Surgery for primary cardiac tumors in children has good early and long-term outcomes, with low recurrence rate. Rhabdomyomas are the most frequent surgical histotypes. Malignant tumors negatively affect early and late survival. Heart transplant is indicated when conservative surgery is not feasible. Lack of recurrence after partial resection of benign cardiac tumors indicates that a less risky tumor debulking is effective for a subset of histotypes such as rhabdomyomas and fibromas. [ABSTRACT FROM AUTHOR]
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- 2012
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13. Scimitar syndrome: a European Congenital Heart Surgeons Association (ECHSA) multicentric study.
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Vida VL, Padalino MA, Boccuzzo G, Tarja E, Berggren H, Carrel T, Ciçek S, Crupi G, Di Carlo D, Di Donato R, Fragata J, Hazekamp M, Hraska V, Maruszewski B, Metras D, Pozzi M, Pretre R, Rubay J, Sairanen H, and Sarris G
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- 2010
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14. Improvement in congenital heart surgery in a developing country: the Guatemalan experience.
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Larrazabal LA, Jenkins KJ, Gauvreau K, Vida VL, Benavidez OJ, Gaitán GA, Garcia F, Castañeda AR, Larrazabal, Luis A, Jenkins, Kathy J, Gauvreau, Kimberlee, Vida, Vladimiro L, Benavidez, Oscar J, Gaitán, Guillermo A, Garcia, Flor, and Castañeda, Aldo R
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- 2007
15. Giant intramural left ventricular rhabdomyoma in a newborn.
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Padalino MA, Vida VL, Bhattarai A, Reffo E, Milanesi O, Thiene G, Stellin G, and Basso C
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- 2011
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16. Cardiac herniation after minimally invasive cardiac surgery: an unusual potentially lethal complication.
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Speggiorin S, Padalino MA, Vida VL, Bonato R, Stellin G, Speggiorin, Simone, Padalino, Massimo A, Vida, Vladimiro L, Bonato, Raffaele, and Stellin, Giovanni
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- 2009
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17. Club 35 Poster Session Wednesday 11 December: 11/12/2013, 09:30-16:00 * Location: Poster area
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Montoro Lopez, M, Pons De Antonio, I, Itziar Soto, C, Florez Gomez, R, Alonso Ladreda, A, Rios Blanco, JJ, Refoyo Salicio, E, Moreno Yanguela, M, Lopez Sendon, JL, Guzman Martinez, G, Van De Heyning, C M, Magne, J, Pierard, LA, Bruyere, PJ, Davin, L, De Maeyer, C, Paelinck, BP, Vrints, CJ, Lancellotti, P, Michalski, BW, Krzeminska-Pakula, M, Lipiec, P, Szymczyk, E, Chrzanowski, L, Kasprzak, JD, Leao, R N, Florencio, A F, Oliveira, A R, Bento, B, Lopes, S, Calaca, J, Palma Reis, R, Krestjyaninov, MV, Gimaev, RH, Razin, VA, Arangalage, D, Chiampan, A, Cimadevilla, C, Touati, A, Himbert, D, Brochet, E, Iung, B, Nataf, P, Vahanian, A, Messika-Zeitoun, D, Guvenc, TS, Karacimen, D, Erer, HB, Ilhan, E, Sayar, N, Karakus, G, Eren, M, Iriart, X, Tafer, N, Roubertie, F, Mauriat, P, Thambo, JB, Wang, J, Fang, F, Yip, G WK, Sanderson, J, Feng, W, Yu, CM, Lam, YY, Assabiny, A, Apor, A, Nagy, A, Vago, H, Toth, A, Merkely, B, Kovacs, A, Castaldi, B, Vida, VL, Guariento, A, Padalino, M, Cerutti, A, Maschietto, N, Biffanti, R, Reffo, E, Stellin, G, Milanesi, O, Baronaite-Dudoniene, K, Urbaite, L, Smalinskas, V, Veisaite, R, Vasylius, T, Vaskelyte, J, Puodziukynas, A, Wieczorek, J, Rybicka-Musialik, A, Berger-Kucza, A, Hoffmann, A, Wnuk-Wojnar, A, Mizia-Stec, K, Melao, F, Ribeiro, V, Amorim, S, Araujo, C, Torres, JP, Cardoso, JS, Pinho, P, Maciel, MJ, Storsten, P, Eriksen, M, Boe, E, Estensen, ME, Erikssen, G, Smiseth, OA, Skulstad, H, Miglioranza, MH, Gargani, L, Sant`Anna, RT, Rover, M, Martins, VM, Mantovanni, A, Kalil, RK, Leiria, TL, Luo, XX, Fang, F, Lee, PW, Zhang, ZH, Lam, YY, Sanderson, JE, Kwong, J SW, Yu, CM, Borowiec, A, Dabrowski, R, Wozniak, J, Jasek, S, Chwyczko, T, Kowalik, I, Janas, J, Musiej-Nowakowska, E, Szwed, H, Palinsky, M, Petrovicova, J, Pirscova, M, Baricevic, Z, Lovric, D, Cikes, M, Skoric, B, Ljubas Macek, J, Reskovic Luksic, V, Separovic Hanzevacki, J, Milicic, D, Elmissiri, AM, El Shahid, GS, Abdal-Wahhab, S, Vural, M G, Yilmaz, M, Cetin, S, Akdemir, R, Yoldas, T K, Yeter, E, Karamanou, AG, Hamodraka, ES, Lekakis, IA, Paraskevaidis, IA, Kremastinos, DT, Appiah-Dwomoh, E K, Wang, VC, Otto, C, Mayar, F, Bonaventura, K, Sunman, H, Canpolat, U, Kuyumcu, M, Yorgun, H, Sahiner, L, and Ozer, N
- Abstract
Purpose: It is known the higher prevalence of structural heart disease in HIV patients, mostly diastolic dysfunction and pulmonary hypertension. In spite of that, there are few data about predisposing factors. Our objective was to evaluate whether HIV stage or detectable blood viral load correlate with the degree of heart disease. Methods: We conducted a prospective cohort study with HIV patients monitored by the internal medicine unit of our institution. We selected symptomatic patients with functional class ≥ II of NYHA scale. Viral blood load and CD4 count were systematically determined in order to obtain the HIV stage. Patients underwent a transthoracic echocardiogram to assess ventricular hypertrophy, systolic and diastolic dysfunction and pulmonary hypertension, according to the limits set by ESC guidelines. Results: Data were obtained from 65 HIV patients with dyspnea (63% male) with a mean age of 48 years. 50% were in NYHA grade II, 32.3% III and 17.7% IV. 46.7% of patients had some data of structural heart disease (figure). Belong to AIDS group (65.3%) did not correlate with the degree of heart disease. However, patients with positive blood viral load had a significantly higher incidence of structural heart disease than those with undetectable load (75% vs. 43% p <0.04), independent of their cardiovascular risk profile or type of antiretroviral therapy (Table). Conclusion: In our experience, half of HIV patients with dyspnea show echocardiographic data of structural heart disease. Detectable viral load in blood doubles the prevalence of heart disease, so that HIV itself may be an independent causal agent. These data should be taken into account in the screening of structural heart disease in these patients.
Figure Prevalence of structural heart disease - Published
- 2013
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18. Poster session Friday 13 December - PM: 13/12/2013, 14:00-18:00 * Location: Poster area
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Caiani, EG, Pellegrini, A, Carminati, MC, Lang, RM, Auricchio, A, Vaida, P, Obase, K, Sakakura, T, Komeda, M, Okura, H, Yoshida, K, Zeppellini, R, Noni, M, Rigo, T, Erente, G, Carasi, M, Costa, A, Ramondo, BA, Thorell, L, Akesson-Lindow, T, Shahgaldi, K, Germanakis, I, Fotaki, A, Peppes, S, Sifakis, S, Parthenakis, F, Makrigiannakis, A, Richter, U, Sveric, K, Forkmann, M, Wunderlich, C, Strasser, RH, Djikic, D, Potpara, T, Polovina, M, Marcetic, Z, Peric, V, Ostenfeld, E, Werther-Evaldsson, A, Engblom, H, Ingvarsson, A, Roijer, A, Meurling, C, Holm, J, Radegran, G, Carlsson, M, Tabuchi, H, Yamanaka, T, Katahira, Y, Tanaka, M, Kurokawa, T, Nakajima, H, Ohtsuki, S, Saijo, Y, Yambe, T, Dalto, M, Romeo, E, Argiento, P, Dandrea, A, Vanderpool, R, Correra, A, Sarubbi, B, Calabro, R, Russo, MG, Naeije, R, Saha, S K, Warsame, T A, Caelian, A G, Malicse, M, Kiotsekoglou, A, Omran, A S, Sharif, D, Sharif-Rasslan, A, Shahla, C, Khalil, A, Rosenschein, U, Erturk, M, Oner, E, Kalkan, AK, Pusuroglu, H, Ozyilmaz, S, Akgul, O, Aksu, HU, Akturk, F, Celik, O, Uslu, N, Bandera, F, Pellegrino, M, Generati, G, Donghi, V, Alfonzetti, E, Guazzi, M, Rangel, I, Goncalves, A, Sousa, C, Correia, AS, Martins, E, Silva-Cardoso, J, Macedo, F, Maciel, MJ, Lee, S, Kim, W, Yun, H, Jung, L, Kim, E, Ko, J, Enescu, OA, Florescu, M, Rimbas, RC, Cinteza, M, Vinereanu, D, Kosmala, W, Rojek, A, Cielecka-Prynda, M, Laczmanski, L, Mysiak, A, Przewlocka-Kosmala, M, Liu, D, Hu, K, Niemann, M, Herrmann, S, Cikes, M, Gaudron, PD, Knop, S, Ertl, G, Bijnens, B, Weidemann, F, Saravi, M, Tamadoni, AHMAD, Jalalian, ROZITA, Hojati, MOSTAF, Ramezani, SAEED, Yildiz, A, Inci, U, Bilik, MZ, Yuksel, M, Oyumlu, M, Kayan, F, Ozaydogdu, N, Aydin, M, Akil, MA, Tekbas, E, Shang, Q, Zhang, Q, Fang, F, Wang, S, Li, R, Lee, A PW, Yu, CM, Mornos, C, Ionac, A, Cozma, D, Popescu, I, Ionescu, G, Dan, R, Petrescu, L, Sawant, AC, Srivatsa, SV, Adhikari, P, Mills, PK, Srivatsa, SS, Boshchenko, A, Vrublevsky, A, Karpov, R, Trifunovic, D, Stankovic, S, Vujisic-Tesic, B, Petrovic, M, Nedeljkovic, I, Banovic, M, Tesic, M, Petrovic, M, Dragovic, M, Ostojic, M, Zencirci, E, Esen Zencirci, A, Degirmencioglu, A, Karakus, G, Ekmekci, A, Erdem, A, Ozden, K, Erer, HB, Akyol, A, Eren, M, Zamfir, D, Tautu, O, Onciul, S, Marinescu, C, Onut, R, Comanescu, I, Oprescu, N, Iancovici, S, Dorobantu, M, Melao, F, Pereira, M, Ribeiro, V, Oliveira, S, Araujo, C, Subirana, I, Marrugat, J, Dias, P, Azevedo, A, study, EURHOBOP, Grillo, M T, Piamonti, B, Abate, E, Porto, A, Dellangela, L, Gatti, G, Poletti, A, Pappalardo, A, Sinagra, G, Pinto-Teixeira, P, Galrinho, A, Branco, L, Fiarresga, A, Sousa, L, Cacela, D, Portugal, G, Rio, P, Abreu, J, Ferreira, R, Fadel, B, Abdullah, N, Al-Admawi, M, Pergola, V, Bech-Hanssen, O, Di Salvo, G, Tigen, M K, Pala, S, Karaahmet, T, Dundar, C, Bulut, M, Izgi, A, Esen, A M, Kirma, C, Boerlage-Van Dijk, K, Yamawaki, M, Wiegerinck, EMA, Meregalli, PG, Bindraban, NR, Vis, MM, Koch, KT, Piek, JJ, Bouma, BJ, Baan, J, Mizia, M, Sikora-Puz, A, Gieszczyk-Strozik, K, Lasota, B, Chmiel, A, Chudek, J, Jasinski, M, Deja, M, Mizia-Stec, K, Silva Fazendas Adame, P R, Caldeira, D, Stuart, B, Almeida, S, Cruz, I, Ferreira, A, Lopes, L, Joao, I, Cotrim, C, Pereira, H, Unger, P, Dedobbeleer, C, Stoupel, E, Preumont, N, Argacha, JF, Berkenboom, G, Van Camp, G, Malev, E, Reeva, S, Vasina, L, Pshepiy, A, Korshunova, A, Timofeev, E, Zemtsovsky, E, Jorgensen, P G, Jensen, JS, Fritz-Hansen, T, Biering-Sorensen, T, Jons, C, Olsen, NT, Henri, C, Magne, J, Dulgheru, R, Laaraibi, S, Voilliot, D, Kou, S, Pierard, L, Lancellotti, P, Tayyareci, Y, Dworakowski, R, Kogoj, P, Reiken, J, Kenny, C, Maccarthy, P, Wendler, O, Monaghan, MJ, Song, JM, Ha, TY, Jung, YJ, Seo, MO, Choi, SA, Kim, YJ, Sun, BJ, Kim, DH, Kang, DH, Song, JK, Le Tourneau, T, Topilsky, Y, Inamo, J, Mahoney, D, Suri, R, Schaff, H, Enriquez-Sarano, M, Bonaque Gonzalez, JC, Sanchez Espino, AD, Merchan Ortega, G, Bolivar Herrera, N, Ikuta, I, Macancela Quinonez, JJ, Munoz Troyano, S, Ferrer Lopez, R, Gomez Recio, M, Dreyfus, J, Cimadevilla, C, Brochet, E, Himbert, D, Iung, B, Vahanian, A, Messika-Zeitoun, D, Izumo, M, Takeuchi, M, Seo, Y, Yamashita, E, Suzuki, K, Ishizu, T, Sato, K, Aonuma, K, Otsuji, Y, Akashi, YJ, Muraru, D, Addetia, K, Veronesi, F, Corsi, C, Mor-Avi, V, Yamat, M, Weinert, L, Lang, RM, Badano, LP, Minamisawa, M, Koyama, J, Kozuka, A, Motoki, H, Izawa, A, Tomita, T, Miyashita, Y, Ikeda, U, Florescu, C, Niemann, M, Liu, D, Hu, K, Herrmann, S, Gaudron, PD, Scholz, F, Stoerk, S, Ertl, G, Weidemann, F, Marchel, M, Serafin, A, Kochanowski, J, Piatkowski, R, Madej-Pilarczyk, A, Filipiak, KJ, Hausmanowa-Petrusewicz, I, Opolski, G, Meimoun, P, Mbarek, D, Clerc, J, Neikova, A, Elmkies, F, Tzvetkov, B, Luycx-Bore, A, Cardoso, C, Zemir, H, Mansencal, N, Arslan, M, El Mahmoud, R, Pilliere, R, Dubourg, O, Ikonomidis, I, Lambadiari, V, Pavlidis, G, Koukoulis, C, Kousathana, F, Varoudi, M, Tritakis, V, Triantafyllidi, H, Dimitriadis, G, Lekakis, I, Kovacs, A, Kosztin, A, Solymossy, K, Celeng, C, Apor, A, Faludi, M, Berta, K, Szeplaki, G, Foldes, G, Merkely, B, Kimura, K, Daimon, M, Nakajima, T, Motoyoshi, Y, Komori, T, Nakao, T, Kawata, T, Uno, K, Takenaka, K, Komuro, I, Gabric, I D, Vazdar, LJ, Pintaric, H, Planinc, D, Vinter, O, Trbusic, M, Bulj, N, Nobre Menezes, M, Silva Marques, J, Magalhaes, R, Carvalho, V, Costa, P, Brito, D, Almeida, AG, Nunes-Diogo, AG, Davidsen, E S, Bergerot, C, Ernande, L, Barthelet, M, Thivolet, S, Decker-Bellaton, A, Altman, M, Thibault, H, Moulin, P, Derumeaux, G, Huttin, O, Voilliot, D, Frikha, Z, Aliot, E, Venner, C, Juilliere, Y, Selton-Suty, C, Yamada, T, Ooshima, M, Hayashi, H, Okabe, S, Johno, H, Murata, H, Charalampopoulos, A, Tzoulaki, I, Howard, LS, Davies, RJ, Gin-Sing, W, Grapsa, J, Wilkins, MR, Gibbs, JSR, Castillo, JMDC, Bandeira, AMPB, Albuquerque, ESA, Silveira, C, Pyankov, V, Chuyasova, Y, Lichodziejewska, B, Goliszek, S, Kurnicka, K, Dzikowska Diduch, O, Kostrubiec, M, Krupa, M, Grudzka, K, Ciurzynski, M, Palczewski, P, Pruszczyk, P, Arana, X, Oria, G, Onaindia, JJ, Rodriguez, I, Velasco, S, Cacicedo, A, Palomar, S, Subinas, A, Zumalde, J, Laraudogoitia, E, Saeed, S, Kokorina, MV, Fromm, A, Oeygarden, H, Waje-Andreassen, U, Gerdts, E, Gomez, ELENA, Vallejo, NURIA, Pedro-Botet, LUISA, Mateu, LOURDE, Nunyez, RAQUEL, Llobera, LAIA, Bayes, ANTONI, Sabria, MIQUEL, Antonini-Canterin, F, Mateescu, AD, La Carrubba, S, Vriz, O, Di Bello, V, Carerj, S, Zito, C, Ginghina, C, Popescu, BA, Nicolosi, GL, Mateescu, AD, La Carrubba, S, Vriz, O, Di Bello, V, Carerj, S, Zito, C, Ginghina, C, Popescu, BA, Nicolosi, GL, Antonini-Canterin, F, Pudil, R, Praus, R, Vasatova, M, Vojacek, J, Palicka, V, Hulek, P, P37/03, Prvouk, Pradel, S, Mohty, D, Damy, T, Echahidi, N, Lavergne, D, Virot, P, Aboyans, V, Jaccard, A, Mateescu, AD, La Carrubba, S, Vriz, O, Di Bello, V, Carerj, S, Zito, C, Ginghina, C, Popescu, BA, Nicolosi, GL, Antonini-Canterin, F, Doulaptsis, C, Symons, R, Matos, A, Florian, A, Masci, PG, Dymarkowski, S, Janssens, S, Bogaert, J, Lestuzzi, C, Moreo, A, Celik, S, Lafaras, C, Dequanter, D, Tomkowski, W, De Biasio, M, Cervesato, E, Massa, L, Imazio, M, Watanabe, N, Kijima, Y, Akagi, T, Toh, N, Oe, H, Nakagawa, K, Tanabe, Y, Ikeda, M, Okada, K, Ito, H, Milanesi, O, Biffanti, R, Varotto, E, Cerutti, A, Reffo, E, Castaldi, B, Maschietto, N, Vida, VL, Padalino, M, Stellin, G, Bejiqi, R, Retkoceri, R, Bejiqi, H, Retkoceri, A, Surdulli, SH, Massoure, PL, Cautela, J, Roche, NC, Chenilleau, MC, Gil, JM, Fourcade, L, Akhundova, A, Cincin, A, Sunbul, M, Sari, I, Tigen, MK, Basaran, Y, Suermeci, G, Butz, T, Schilling, IC, Sasko, B, Liebeton, J, Van Bracht, M, Tzikas, S, Prull, MW, Wennemann, R, Trappe, HJ, Attenhofer Jost, C H, Pfyffer, M, Scharf, C, Seifert, B, Faeh-Gunz, A, Naegeli, B, Candinas, R, Medeiros-Domingo, A, Wierzbowska-Drabik, K, Roszczyk, N, Sobczak, M, Plewka, M, Krecki, R, Kasprzak, JD, Ikonomidis, I, Varoudi, M, Papadavid, E, Theodoropoulos, K, Papadakis, I, Pavlidis, G, Triantafyllidi, H, Anastasiou - Nana, M, Rigopoulos, D, Lekakis, J, Tereshina, O, Surkova, E, Vachev, A, Merchan Ortega, G, Bonaque Gonzalez, JC, Sanchez Espino, AD, Bolivar Herrera, N, Bravo Bustos, D, Ikuta, I, Aguado Martin, MJ, Navarro Garcia, F, Ruiz Lopez, F, Gomez Recio, M, Merchan Ortega, G, Bonaque Gonzalez, JC, Bravo Bustos, D, Sanchez Espino, AD, Bolivar Herrera, N, Bonaque Gonzalez, JJ, Navarro Garcia, F, Aguado Martin, MJ, Ruiz Lopez, MF, Gomez Recio, M, Eguchi, H, Maruo, T, Endo, K, Nakamura, K, Yokota, K, Fuku, Y, Yamamoto, H, Komiya, T, Kadota, K, Mitsudo, K, Nagy, A I, Manouras, AI, Gunyeli, E, Shahgaldi, K, Winter, R, Hoffmann, R, Barletta, G, Von Bardeleben, S, Kasprzak, J, Greis, C, Vanoverschelde, J, Becher, H, Hu, K, Liu, D, Niemann, M, Herrmann, S, Cikes, M, Gaudron, PD, Knop, S, Ertl, G, Bijnens, B, Weidemann, F, Di Salvo, G, Al Bulbul, Z, Issa, Z, Khan, AM, Faiz, AA, Rahmatullah, SH, Fadel, BM, Siblini, G, Al Fayyadh, M, Menting, M E, Van Den Bosch, AE, Mcghie, JS, Cuypers, JAAE, Witsenburg, M, Van Dalen, BM, Geleijnse, ML, Roos-Hesselink, JW, Olsen, FJ, Jorgensen, PG, Mogelvang, R, Jensen, JS, Fritz-Hansen, T, Bech, J, Biering-Sorensen, T, Agoston, G, Pap, R, Saghy, L, Forster, T, Varga, A, Scandura, S, Capodanno, D, Dipasqua, F, Mangiafico, S, Caggegi, A M, Grasso, C, Pistritto, A M, Imme, S, Ministeri, M, Tamburino, C, Cameli, M, Lisi, M, Dascenzi, F, Cameli, P, Losito, M, Sparla, S, Lunghetti, S, Favilli, R, Fineschi, M, Mondillo, S, Ojaghihaghighi, Z, Javani, B, Haghjoo, M, Moladoust, H, Shahrzad, S, Ghadrdoust, B, Altman, M, Aussoleil, A, Bergerot, C, Bonnefoy-Cudraz, E, Derumeaux, G A, Thibault, H, Shkolnik, E, Vasyuk, Y, Nesvetov, V, Shkolnik, L, Varlan, G, Gronkova, N, Kinova, E, Borizanova, A, Goudev, A, Saracoglu, E, Ural, D, Sahin, T, Al, N, Cakmak, H, Akbulut, T, Akay, K, Ural, E, Mushtaq, S, Andreini, D, Pontone, G, Bertella, E, Conte, E, Baggiano, A, Annoni, A, Formenti, A, Fiorentini, C, Pepi, M, Cosgrove, C, Carr, L, Chao, C, Dahiya, A, Prasad, S, Younger, JF, Biering-Sorensen, T, Christensen, LM, Krieger, DW, Mogelvang, R, Jensen, JS, Hojberg, S, Host, N, Karlsen, FM, Christensen, H, Medressova, A, Abikeyeva, L, Dzhetybayeva, S, Andossova, S, Kuatbayev, Y, Bekbossynova, M, Bekbossynov, S, Pya, Y, Farsalinos, K, Tsiapras, D, Kyrzopoulos, S, Spyrou, A, Stefopoulos, C, Romagna, G, Tsimopoulou, K, Tsakalou, M, Voudris, V, Cacicedo, A, Velasco Del Castillo, S, Anton Ladislao, A, Aguirre Larracoechea, U, Onaindia Gandarias, J, Romero Pereiro, A, Arana Achaga, X, Zugazabeitia Irazabal, G, Laraudogoitia Zaldumbide, E, Lekuona Goya, I, Varela, A, Kotsovilis, S, Salagianni, M, Andreakos, V, Davos, CH, Merchan Ortega, G, Bonaque Gonzalez, JC, Sanchez Espino, AD, Bolivar Herrera, N, Macancela Quinones, JJ, Ikuta, I, Ferrer Lopez, R, Munoz Troyano, S, Bravo Bustos, D, and Gomez Recio, M
- Abstract
Purpose: Cardiac deconditioning due to immobilization is a risk factor for cardiovascular disease. The physiology of cardiac adaptation to deconditioning has not been fully elucidated. The purpose of the present study was to assess the effects of 21-days of strict head-down (-6 degrees) bed-rest (BR) deconditioning on left ventricular (LV) dimensions and mass measured by MRI. Methods: Ten healthy men (mean age 32±6) were enrolled; the experiment was conducted at DLR (Koln, Germany) as part of the European Space Agency BR studies. Steady-state free precession MRI images (7mm thickness, no gap, no overlap) were obtained (Symphony 1.5T, Siemens) in a stack of short-axis views from LV base to LV apex, before (PRE), at the end of BR (HDT20), and four days after the BR conclusion (POST). Endocardial and epicardial semi-automated contouring was performed using freely available software (Segment). Results: At HDT20, significant reductions in LV mass (16%), end-diastolic (26%) and end-systolic (27%) volumes and stroke volume (27%) were observed, while ejection fraction did not change. These changes were accompanied by a measured decrease (14%) in plasma and blood volume (by gas-rebreathing technique), as well as by a significant reduction (14%) in VO2max aerobic power, measured using a graded cycle ergometer test protocol to volitional fatigue, at one day after the BR conclusion, while expiratory exchange ratio did not change. At POST, LV volumes were restored, while LV mass was still trending towards control values. Conclusions: Cardiac adaptation to deconditioning affected LV mass and dimensions, as a combined result of LV remodeling and fluids loss, accompanied by worsening in aerobic power. This should be taken into account in patients with cardiovascular diseases, when immobilized in bed, to proper adjust the therapy, or to define appropriate physical exercises when possible, in order to avoid further complications.
Cardiac MRI parameters PRE HDT20 POST LV mass (g) 121±6 102±11* 114±16 End-diastolic volume (ml) 119±25 90±14* 118±25 End-systolic volume (ml) 42±8 31±8* 45±14 Stroke volume (ml) 76±22 59±11* 73±15 Ejection fraction (%) 64±6 65±7 62±7 *: p<.01 vs PRE (one-way Anova for paired data and Tukey test) - Published
- 2013
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19. OC80 THE ROLE OF SURGICAL TECHNIQUE ON LONG-TERM OUTCOMES OF TETRALOGY OF FALLOT REPAIR
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C. Pace Napoleone, R. Giordano, Nicola Pradegan, Stefano M. Marianeschi, Cristina Carro, Lorenzo Galletti, Salvatore Agati, Gaetano Palma, Massimo A. Padalino, Danila Azzolina, Giovanni Stellin, Vladimiro L. Vida, Pradegan, N, Azzolina, D, Galletti, L, Napoleone, C Pace, Agati, S, Palma, G, Giordano, R, Marianeschi, S, Carro, C, Vida, Vl, Stellin, G, and Padalino, Ma
- Subjects
medicine.medical_specialty ,Multicenter study ,business.industry ,medicine ,Long term outcomes ,General Medicine ,Cardiology and Cardiovascular Medicine ,medicine.disease ,business ,Tetralogy of Fallot ,Surgery - Published
- 2018
20. MIDTERM RESULTS OF SURGICAL INTERVENTION FOR CONGENITAL HEART DISEASE IN ADULTS: AN ITALIAN MULTICENTER STUDY
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Giancarlo Crupi, Giovanni Stellin, Raffaele Calabrò, Carlo Vosa, Massimo Bernabei, Giulio Rizzoli, Luciano Daliento, Gaetano Gargiulo, Alessandro Giamberti, Vladimiro L. Vida, Giuseppe Pacileo, Massimo A. Padalino, Simone Speggiorin, Francesco Santoro, Padalino, M. A., Speggiorin, S., Rizzoli, G., Crupi, G., Vida, V. L., Bernabei, M., Gargiulo, G., Giamberti, A., Santoro, F., Vosa, Carlo, Pacileo, G., Calabro', R., Daliento, L., Stellin, G., M., Padalino, S., Speggiorin, G., Rizzoli, G., Crupi, V. L., Vida, M., Bernabei, G., Gargiulo, A., Giamberti, F., Santoro, G., Pacileo, R., Calabro', L., Daliento, G., Stellin, Padalino MA., Speggiorin S., Rizzoli G., Crupi G., Vida VL., Bernabei M., Gargiulo G., Giamberti A., Santoro F., Vosa C., Pacileo G., Calabrò R., Daliento L., and Stellin G.
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Adult ,Heart Defects, Congenital ,Male ,Reoperation ,Pulmonary and Respiratory Medicine ,Cardiac Catheterization ,medicine.medical_specialty ,New York Heart Association Class ,Heart disease ,law.invention ,law ,Humans ,Medicine ,Sinus rhythm ,Hospital Mortality ,Adverse effect ,Aged ,New York Heart Association Class I ,Aged, 80 and over ,business.industry ,Data Collection ,Palliative Care ,Hazard ratio ,Length of Stay ,Middle Aged ,medicine.disease ,Survival Analysis ,Intensive care unit ,Echocardiography, Doppler ,Surgery ,Cardiac surgery ,Treatment Outcome ,Multivariate Analysis ,Female ,Cardiology and Cardiovascular Medicine ,business ,Follow-Up Studies - Abstract
Objective We have analyzed, in a clinical multicenter study, the effect of cardiac surgery in adults with congenital heart disease in Italy. Methods We collected clinical data from 856 patients aged 19 years or older who underwent surgical intervention from January 1, 2000, to December 31, 2004. Patients were divided into 3 surgical groups: group 1, palliation (3.1%); group 2, repair (69.7%); and group 3, reoperation (27.4%). Results Preoperatively, 34.6% of patients were in New York Heart Association class I, 48.4% were in class II, 14.2% were in class III, and 2.8% were in class IV. Sinus rhythm was present in 83%. There were 1179 procedures performed in 856 patients (1.37 procedures per patient), with a hospital mortality of 3.1%. Overall mean intensive care unit stay was 2.3 days (range, 1–102 days). Major complications were reported in 247 (28.8%) patients, and postoperative arrhythmias were the most frequent. At a mean follow-up of 22 months (range, 1 month–5.5 years; completeness, 87%), late death occurred in 5 (0.5%) patients. New York Heart Association class was I in 79.3%, II in 17.6%, and III in 2.9%, and only 1 (0.11%) patient was in class IV. Overall survival estimates are 82.6%, 98.9%, and 91.8% at 5 years for groups 1, 2, and 3, respectively. Freedom from adverse events at 5 years is 91% for acyanotic patients versus 63.9% for preoperative cyanotic patients ( P Conclusions Surgical intervention for congenital heart disease in adults is a safe and low-risk treatment. However, patients presenting with preoperative cyanosis show a higher incidence of late adverse events and complications.
- Published
- 2007
21. Outcomes of Neonatal Cardiac Surgery: a European Congenital Heart Surgeons Association Study.
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Cattapan C, Jacobs JP, Bleiweis MS, Sarris GE, Tobota Z, Guariento A, Maruszewski B, Staffa SJ, Zurakowski D, and Vida VL
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Background: We evaluated outcomes of neonatal cardiac surgery at hospitals affiliated with the European Congenital Heart Surgeons Association (ECHSA)., Methods: All patients ≤30 days of life undergoing a cardiac surgical procedure during a 10 year period between January 2013 and December 2022 were selected from the ECHSA Congenital Database. Reoperations during the same hospitalization, percutaneous procedures, and noncardiac surgical procedures were excluded. A total of 12 benchmark operations were identified. Primary outcomes were 30-day mortality and in-hospital mortality. Multivariable logistic regression analysis was performed to determine independent factors associated with higher mortality. A comparison of mortality between the first 5 years and second 5 years was also performed., Results: The overall number of neonatal operations from 2013-2022 was 30,931, and 22,763 patients met the inclusion criteria of the study. The four most common procedures were: arterial switch operation (3,520/22,763=15.5%), aortic coarctation repair (3,204/22,763=14.1%), shunt procedure (2,351/22,763=10.3%), and Norwood Operation (2,115/22,763=9.23%). 30-day mortality rate was: overall population (1,342/22,763=5.9%), arterial switch (110/3,520=3.13%), Norwood Operation (339/2,115=16.0%), and hybrid operation (94/609=15.4%). In-hospital mortality rate was: overall population (2,074/22,763=9.1%), arterial switch (145/3,520=4.12%), Norwood Operation (523/2,115=24.7%), and hybrid operation (186/609=30.5%). Multivariable analysis revealed that major factors impacting mortality were high risk procedures (adjusted odds ratio=2.74 [95% confidence interval=2.33-3.23]; p<0.001), and the need for extracorporeal membrane oxygenation (11.8 [9.9-14]; p <0.001)., Conclusions: Neonatal cardiac surgery continues to pose a significant challenge, with notable mortality, particularly for neonates with functionally univentricular physiology. These data can serve as important benchmarks across Europe and offer insights regarding opportunities for improvement., (Copyright © 2024. Published by Elsevier Inc.)
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- 2024
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22. Nationwide hospitalizations of patients with down syndrome and congenital heart disease over a 15-year period.
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Guariento A, Cattapan C, Lorenzoni G, Guerra G, Doulamis IP, di Salvo G, Gregori D, and Vida VL
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- Humans, Female, Male, Italy epidemiology, Child, Adolescent, Child, Preschool, Infant, Adult, Young Adult, Retrospective Studies, Infant, Newborn, Patient Readmission statistics & numerical data, Middle Aged, Risk Factors, Down Syndrome complications, Down Syndrome epidemiology, Heart Defects, Congenital epidemiology, Heart Defects, Congenital mortality, Hospitalization statistics & numerical data
- Abstract
Down syndrome is one of the most common genetic diseases, generally associated with an increased probability of congenital heart diseases. This increased risk contributes to escalated levels of morbidity and mortality. In this study, we sought to analyze nationwide data of pediatric and adult patients with Down syndrome and congenital heart disease over a 15-year period. Data obtained from the hospital discharge form between 2001 and 2016 of patients diagnosed with Down syndrome in Italy and at least one congenital heart disease were included. Information on 12362 admissions of 6527 patients were included. Age at first admission was 6.2 ± 12.8 years and was a predictor of mortality (HR = 1.51, 95% CI 1.13-2.03, p = 0.006). 3923 (60.1%) patients underwent only one admission, while 2604 (39.9%) underwent multiple (> 1) admissions. There were 5846 (47.3%) admissions for cardiac related symptoms. Multiple admissions (SHR: 3.13; 95% CI: 2.99, 3.27; P < 0.01) and cardiac admissions (SHR: 2.00; 95% CI: 1.92, 2.09; P < 0.01) were associated with an increased risk of additional potential readmissions. There was an increased risk of mortality for patients who had cardiac admissions (HR = 1.45, 95% CI: 1.08-1.94, p = 0.012), and for those who underwent at least 1 cardiac surgical procedure (HR = 1.51, 95% CI 1.13-2.03, p = 0.006)., Conclusions: A younger age at first admission is a predictor for mortality in patients with Down syndrome and congenital heart disease. If patients undergo more than one admission, the risk of further readmissions increases. There is a pivotal role for heart disease in influencing the hospitalization rate and subsequent mortality., What Is Known: • Down syndrome individuals often face an increased risk of congenital heart diseases. • Congenital heart diseases contribute significantly to morbidity and mortality in Down syndrome patients., What Is New: • This study analyzes nationwide data covering a 15-year period of pediatric and adult patients in Italy with Down syndrome and congenital heart disease. • It identifies a younger age at first admission as a predictor for mortality in these patients, emphasizing the criticality of early intervention. • Demonstrates a correlation between multiple admissions, particularly those related to cardiac issues, and an increased risk of further readmissions, providing insights into the ongoing healthcare needs of these individuals., (© 2024. The Author(s).)
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- 2024
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23. Enhancing parental understanding of congenital heart disease through personalized prenatal counseling with 3D printed hearts.
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Galliotto F, Veronese P, Cerutti A, Zemin F, Bertelli F, Di Salvo G, Guariento A, and Vida VL
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- Humans, Female, Pregnancy, Adult, Pilot Projects, Fetal Heart diagnostic imaging, Heart Defects, Congenital diagnostic imaging, Printing, Three-Dimensional, Parents psychology, Counseling methods, Ultrasonography, Prenatal methods
- Abstract
Objectives: In addition to a correct prenatal diagnosis of congenital heart disease (CHD), comprehensive parental counseling is crucial to ensure that parents are well-informed about the condition of the fetus. This study aims to investigate whether there is a significant difference in the information acquired by parents through traditional counseling, utilizing 2-dimensional (2D) illustrations and images, compared to an advanced approach utilizing personalized three-dimensional (3D) printed models of the fetal heart developed from 3D ultrasound imaging., Methods: This study, designed as a pilot randomized control trial, enrolled pregnant women with gestational ages greater than 18 weeks, whose fetuses were diagnosed with CHD and referred to our center between November, 2020 and June, 2021. Two groups of patients were included in the study. The first group received standard medical counseling with 2D images and illustrations, while the second group underwent advanced counseling with 3D-printed patient-specific heart models. Both groups were then required to complete the same survey in which the knowledge of the CHD was investigated. The 3D models were created from 3D ultrasound imaging and printed using resin materials in both 1:1 and 5:1 scale., Results: A comparison of the scores obtained from the two groups revealed that 3D visualization of the fetus's heart has the potential to increase parental knowledge about CHD and the required surgical procedures. Furthermore, all couples expressed interest in receiving a 1:1 scale model of their baby's heart., Conclusion: Personalized prenatal counseling with 3D-ultrasound-based heart models positively impacts parents' understanding of CHD. The use of 3D models provides a more comprehensive and accessible representation of the condition, contributing to an increased knowledge gain, and potentially helping to support informed decisions regarding their child's care., (© 2024 John Wiley & Sons Ltd.)
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- 2024
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24. Decellularized cryopreserved human pericardium: a validation study towards tissue bank practice.
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Montagner G, Barbazza A, Lugas AT, Terzini M, Serino G, Bignardi C, Cacciatore M, Vida VL, Padalino MA, and Trojan D
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- Humans, Decellularized Extracellular Matrix chemistry, Collagen chemistry, Biomechanical Phenomena, Pericardium cytology, Cryopreservation methods, Tissue Banks
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Pericardial patches are currently used as reconstructive material in cardiac surgery for surgical treatment of cardiac septal defects. Autologous pericardial patches, either treated with glutaraldehyde or not, can be used as an alternative to synthetic materials or xenograft in congenital septal defects repair. The availability of an allogenic decellularized pericardium could reduce complication during and after surgery and could be a valid alternative. Decellularization of allogenic tissues aims at reducing the immunogenic reaction that might trigger inflammation and tissue calcification over time. The ideal graft for congenital heart disease repair should be biocompatible, mechanically resistant, non-immunogenic, and should have the ability to growth with the patients. The aim of the present study is the evaluation of the efficacy of a new decellularization protocol of homologous pericardium, even after cryopreservation. The technique has proven to be suitable as a tissue bank procedure and highly successful in the removal of cells and nucleic acids content, but also in the preservation of collagen and biomechanical properties of the human pericardium., (© 2023. The Author(s).)
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- 2024
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25. Minimally invasive paediatric cardiac surgery: steal from the rich and give to the poor.
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Pradegan N and Vida VL
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- Humans, Child, Heart Defects, Congenital surgery, Minimally Invasive Surgical Procedures methods, Cardiac Surgical Procedures methods
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- 2024
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26. Supravalvular aortic stenosis: the long-term story of a mischievous disease.
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Guariento A and Vida VL
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- Humans, Aortic Stenosis, Supravalvular diagnostic imaging, Aortic Stenosis, Supravalvular surgery, Aortic Valve Stenosis surgery
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- 2024
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27. Editorial: Case reports in pediatric cardiology 2022.
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Guariento A, Bertelli F, and Vida VL
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Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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- 2023
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28. Commentary: Prosthetic infective endocarditis: Do we have the solution in our back pocket?
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Oh N, Guariento A, and Vida VL
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- Humans, Endocarditis, Bacterial diagnosis, Endocarditis, Bacterial surgery, Endocarditis diagnosis, Endocarditis etiology, Endocarditis surgery, Heart Valve Prosthesis, Prosthesis-Related Infections diagnosis, Prosthesis-Related Infections surgery
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- 2023
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29. Late left ventricular myocardial remodeling after pulmonary artery banding for end-stage dilated cardiomyopathy in infants: an imaging study.
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Ponzoni M, Zanella L, Reffo E, Cavaliere A, Pozza A, Castaldi B, Di Salvo G, Vida VL, and Padalino MA
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- Child, Humans, Infant, Ventricular Remodeling physiology, Pulmonary Artery diagnostic imaging, Pulmonary Artery surgery, Ventricular Function, Left, Myocardium pathology, Fibrosis, Cardiomyopathy, Dilated diagnostic imaging, Cardiomyopathy, Dilated surgery, Cardiomyopathy, Dilated pathology
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Background: Understanding the macroscopic biventricular changes induced by pulmonary artery banding (PAB) in children with dilated cardiomyopathy (DCM) represents the first step to unraveling the regenerative potential of the myocardium. We herein investigated the phases of left ventricular (LV) rehabilitation in PAB responders, using a systematic echocardiographic and cardiac magnetic imaging (CMRI) surveillance protocol., Methods: We prospectively enrolled all patients with DCM treated with PAB from September-2015 at our institution. Among 9 patients, 7 positively responded to PAB and were selected. Transthoracic 2D echocardiography was performed before PAB; and 30, 60, 90, and 120 days after PAB; and at the last available follow-up. CMRI was performed before PAB (whenever possible) and one year after PAB., Results: In PAB responders, LV ejection fraction showed a modest 10% increase 30-60 days after PAB, followed by its almost complete normalization after 120 days (median of 20[10-26]% vs 56[44.5-63.5]%, at baseline and 120 days after PAB, respectively). Parallelly, the LV end-diastolic volume decreased from a median of 146(87-204)ml/m2 to 48(40-50)ml/m2. At the last available follow-up (median of 1.5 years from PAB), both echocardiography and CMRI showed a sustained positive LV response, although myocardial fibrosis was detected in all patients., Conclusions: Echocardiography and CMRI show that PAB can promote a LV remodeling process, which starts slowly and can culminate in the normalization of LV contractility and dimensions 4 months later. These results are maintained up to 1.5 years. However, CMRI showed residual fibrosis as evidence of a past inflammatory injury whose prognostic significance is still uncertain., Competing Interests: Declaration of Competing Interest The authors report no relationships that could be construed as a conflict of interest., (Copyright © 2023 Elsevier B.V. All rights reserved.)
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- 2023
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30. Tricuspid Valve Repair Can Restore the Prognosis of Patients with Hypoplastic Left Heart Syndrome and Tricuspid Valve Regurgitation: A Meta-analysis.
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Ponzoni M, Azzolina D, Vedovelli L, Gregori D, Vida VL, and Padalino MA
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To date, evidence supporting the efficacy of tricuspid valve (TV) repair in interrupting the progression of systemic right ventricular (RV) adverse remodeling in hypoplastic left heart syndrome (HLHS) is conflicting. We conducted a systematic review and meta-analysis of scientific literature to assess the impact of TV repair in effectively modifying the prognosis of patients with HLHS. We conducted a systematic review of PubMed, Web of Science, and Scopus databases. A random-effect meta-analysis was performed and transplant-free survival, freedom from TV regurgitation, and TV reoperation data were reconstructed using the published Kaplan-Meier curves. Nine studies were included, comprising 203 HLHS patients undergoing TV repair and 323 HLHS controls. The estimated transplant-free survival at 1, 5, and 10 years of follow-up was 75.5% [95% confidence interval (CI) = 67.6-84.3%], 63.6% [95% CI = 54.6-73.9%], and 61.9% [95% CI = 52.7-72.6%], respectively. Transplant-free survival was comparable to HLHS peers without TV regurgitation (p = 0.59). Five-year freedom from recurrence of TV regurgitation and freedom from TV reoperation was 57% [95% CI = 46.7-69.7%] and 63.6% [95% CI = 54.5-74.3%], respectively. Younger age and TV repair at the time of Norwood operation increased the risk of TV regurgitation recurrence and the need for TV reoperation. Our meta-analysis supports the efficacy of TV repair in favorably modifying the prognosis of patients with HLHS and TV regurgitation, reestablishing a medium-term transplant-free survival which is comparable to HLHS peers. However, durability of surgery and long-term fate of TV and RV performance are still unclear., (© 2023. The Author(s).)
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- 2023
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31. Combining Congenital Heart Surgical and Interventional Cardiology Outcome Data in a Single Database: The Development of a Patient-Centered Collaboration of the European Congenital Heart Surgeons Association (ECHSA) and the Association for European Paediatric and Congenital Cardiology (AEPC).
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Jacobs JP, Krasemann T, Herbst C, Tobota Z, Maruszewski B, Fragata J, Ebels T, Vida VL, Mattila I, Kansy A, Asfour B, Hörer J, Lotto AA, Sertaç Çiçek M, Liuba P, Dittrich S, Chessa M, Bökenkamp R, Sharland G, Hanséus K, Blom NA, and Sarris GE
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- Humans, Child, Quality of Life, Patient-Centered Care, Cardiovascular System, Cardiology, Surgeons
- Abstract
The European Congenital Heart Surgeons Association (ECHSA) Congenital Database (CD) is the second largest clinical pediatric and congenital cardiac surgical database in the world and the largest in Europe, where various smaller national or regional databases exist. Despite the dramatic increase in interventional cardiology procedures over recent years, only scattered national or regional databases of such procedures exist in Europe. Most importantly, no congenital cardiac database exists in the world that seamlessly combines both surgical and interventional cardiology data on an international level; therefore, the outcomes of surgical and interventional procedures performed on the same or similar patients cannot easily be tracked, assessed, and analyzed. In order to fill this important gap in our capability to gather and analyze information on our common patients, ECHSA and The Association for European Paediatric and Congenital Cardiology (AEPC) have embarked on a collaborative effort to expand the ECHSA-CD with a new module designed to capture data about interventional cardiology procedures. The purpose of this manuscript is to describe the concept, the structure, and the function of the new AEPC Interventional Cardiology Part of the ECHSA-CD , as well as the potentially valuable synergies provided by the shared interventional and surgical analyses of outcomes of patients. The new AEPC Interventional Cardiology Part of the ECHSA-CD will allow centers to have access to robust surgical and transcatheter outcome data from their own center, as well as robust national and international aggregate outcome data for benchmarking. Each contributing center or department will have access to their own data, as well as aggregate data from the AEPC Interventional Cardiology Part of the ECHSA-CD . The new AEPC Interventional Cardiology Part of the ECHSA-CD will allow cardiology centers to have access to aggregate cardiology data, just as surgical centers already have access to aggregate surgical data. Comparison of surgical and catheter interventional outcomes could potentially strengthen decision processes. A study of the wealth of information collected in the database could potentially also contribute toward improved early and late survival, as well as enhanced quality of life of patients with pediatric and/or congenital heart disease treated with surgery and interventional cardiac catheterization across Europe and the world.
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- 2023
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32. Free interactive mobile app with 3D-reconstructed virtual models of congenital heart disease for prenatal parental counseling.
- Author
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Bertelli F, Guariento A, Gervasi MT, Galliotto F, Sirico D, Blitzer D, Veronese P, and Vida VL
- Subjects
- Pregnancy, Female, Humans, Parents, Counseling, Mobile Applications, Heart Defects, Congenital diagnostic imaging
- Published
- 2023
- Full Text
- View/download PDF
33. Fast-track virtual reality software to facilitate 3-dimensional reconstruction in congenital heart disease.
- Author
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Bertelli F, Raimondi F, Godard C, Bergonzoni E, Cattapan C, Gastino E, Galliotto F, Boddaert N, El Beheiry M, Masson JB, Guariento A, and Vida VL
- Abstract
Objectives: Two limitations of the clinical use of 3-dimensional (3D) reconstruction and virtual reality systems are the relatively high cost and the amount of experience required to use hardware and software to effectively explore medical images. We have tried to simplify the process and validate a new tool developed for this purpose with a novel software package., Methods: Five patients with right partial anomalous pulmonary venous return with adequate preoperative images acquired with magnetic resonance imaging were enrolled. Five volunteers with no previous experience in the field of 3D reconstruction were instructed to use the software after viewing a short video tutorial. Users were then asked to create a 3D model of each patient's heart using DIVA software. Their results were compared quantitatively and qualitatively with a benchmark reconstruction performed by an experienced user., Results: All our participants recreated 3D models in a relatively short time, maintaining a good overall quality (average quality score ≥ 3 on a scale of 1-5). The overall trend of all the parameters analysed showed a statistical improvement between case 1 and case 5, as users became more and more experienced., Conclusions: DIVA is a simple software program that allows accurate 3D reconstruction in a relatively short time ("fast-track" virtual reality). In this study, we demonstrated the potential use of DIVA by inexperienced users, with a significant improvement in quality and time after a few cases were performed. Further studies are needed to confirm the potential application of this technology on a larger scale., (© The Author(s) 2023. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery.)
- Published
- 2023
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34. Sternal-Sparing Transapical, Beating Heart Mitral Valve Repair in an Adult With Repaired Tetralogy of Fallot.
- Author
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Gerosa G, D'Onofrio A, Evangelista G, Vida VL, and Pradegan N
- Abstract
We present the case of a 60-year-old male patient who underwent tetralogy of Fallot repair at 7 years of age and then developed severe degenerative mitral regurgitation during adulthood. Given the increased surgical risk (obesity, obstructive sleep apnea syndrome, and reoperation), the patient underwent a successful microinvasive mitral valve repair with neochordae implantation. ( Level of Difficulty: Advanced. )., Competing Interests: The authors have reported that they have no relationships relevant to the contents of this paper to disclose., (© 2023 Published by Elsevier on behalf of the American College of Cardiology Foundation.)
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- 2023
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- View/download PDF
35. Rescue ross procedure and mitral valve repair on a low birth weight preterm neonate.
- Author
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Garufi L, di Candia A, Bertelli F, Guariento A, and Vida VL
- Subjects
- Aortic Valve abnormalities, Aortic Valve surgery, Child, Follow-Up Studies, Humans, Infant, Low Birth Weight, Infant, Newborn, Mitral Valve surgery, Retrospective Studies, Treatment Outcome, Aortic Valve Insufficiency congenital, Aortic Valve Insufficiency surgery, Aortic Valve Stenosis surgery, Heart Valve Prosthesis Implantation methods, Pulmonary Valve surgery
- Abstract
Although mid- and long-term outcomes after the Ross procedure for aortic valve disease have been increasingly improving over the years, this is still a rather challenging operation in neonates and small children. This is particularly true for patients with associated congenital heart defects and critical clinical conditions. Herein we describe the application of this procedure as a rescue operation in emergency circumstances in a low-birth-weight neonate with severe aortic stenosis, aortic regurgitation and mitral regurgitation after a previous aortic coartectomy., (© 2022 The Authors. Journal of Cardiac Surgery published by Wiley Periodicals LLC.)
- Published
- 2022
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36. Hybrid approach for management of end-stage heart failure in complex congenital heart disease.
- Author
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Tessari C, Castaldi B, Toscano G, Vida VL, Gerosa G, and Padalino MA
- Subjects
- Child, Humans, Treatment Outcome, Heart Defects, Congenital complications, Heart Defects, Congenital surgery, Heart Failure etiology, Heart Failure surgery, Pulmonary Valve surgery
- Abstract
Management of end-stage heart failure (ESHF) in children with congenital heart disease is challenging. We report a step-by-step hybrid procedure (transcatheter pulmonary valve and left mechanical assist device implantations) in a child with ESHF after repair of tetralogy of Fallot, as an effective bridge to transplant strategy.
- Published
- 2022
- Full Text
- View/download PDF
37. Three-dimensional Printing for Hybrid Closure of Complex Muscular Ventricular Septal Defects.
- Author
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Longinotti L, Castaldi B, Bertelli F, Vida VL, and Padalino MA
- Subjects
- Cardiac Catheterization methods, Echocardiography methods, Heart Septal Defects, Ventricular diagnosis, Heart Ventricles diagnostic imaging, Humans, Infant, Newborn, Radiography, Thoracic, Cardiac Surgical Procedures methods, Heart Septal Defects, Ventricular surgery, Heart Ventricles surgery, Printing, Three-Dimensional
- Abstract
The identification and surgical closure of apical complex muscular ventricular septal defects remains a difficult problem because of their location in the ventricular septum distal to the moderating band. Three-dimensional reconstruction can help the surgeon to better understand the location and structure of congenital cardiac defects. We report the case of a child with multiple apical complex muscular ventricular septal defects closed through a hybrid approach with the aid of a 3-dimensional printed model., (Copyright © 2022 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.)
- Published
- 2022
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38. Surgical management of failing Fontan circulation: results from 30 cases with 285 patient-years follow-up.
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Padalino MA, Ponzoni M, Castaldi B, Leoni L, Chemello L, Toscano G, Gerosa G, Di Salvo G, and Vida VL
- Subjects
- Adult, Follow-Up Studies, Humans, Postoperative Complications epidemiology, Postoperative Complications etiology, Postoperative Complications surgery, Reoperation adverse effects, Retrospective Studies, Treatment Outcome, Young Adult, Fontan Procedure methods, Heart Defects, Congenital, Heart Transplantation adverse effects
- Abstract
Objectives: Fontan patients are known to suffer from clinical attrition over the years, which has been characterized as Fontan failure. We sought to evaluate the clinical outcomes of such Fontan patients undergoing surgical management in a 25-year, single-centre experience., Methods: A retrospective single-centre analysis of patients undergoing surgical treatment for failing Fontan between 1995 and 2020, including any reoperations when ventricular function was preserved, or a heart transplant (HTx), when ventricular contractility was impaired. We analysed survival, indications for surgery and early and late complication rates., Results: We collected 30 patients (mean age 24.7 years) who required surgery after a mean time of 19.3 years from the original Fontan procedure: Fontan conversion in 21 (70%, extracardiac conduit in 19, lateral tunnel in 2), a HTx in 4 (13.3%) and other reoperations in 5 (16.7%). The most common indications for surgery were tachyarrhythmias (63.3%) and severe right atrial dilatation (63.3%). Overall survival at the 1-, 5-, 10- and 20-year follow-up examinations were 75.9% [95% confidence interval (CI): 91.4-60.4%], 75.9% (95% CI: 91.4-60.4%), 70% (95% CI: 78-52%) and 70% (95% CI: 78-52%), respectively. The most frequent complications were postoperative tachyarrhythmias (50%) and late Fontan-associated liver disease (56.5%). HTx and Fontan conversion provided comparably good outcomes compared to other reoperations (P = 0.022)., Conclusions: Surgery for failing Fontan can be performed effectively with overall good long-term survival. However, early and late morbidities are still a significant burden. Because other reoperations performed when patients presented with contraindications for a HTx have carried high mortality, close clinical follow-up is mandatory, and an earlier indication for Fontan conversion or a HTx is advisable to optimize outcomes., (© The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.)
- Published
- 2022
- Full Text
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39. Risk evaluation in adult congenital heart surgery: analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database risk models on data from the European Congenital Heart Surgeons Association Congenital Database.
- Author
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Pabst von Ohain J, Sarris G, Tobota Z, Maruszewski B, Vida VL, and Hörer J
- Subjects
- Adolescent, Adult, Databases, Factual, Hospital Mortality, Humans, Risk Assessment, Cardiac Surgical Procedures, Heart Defects, Congenital epidemiology, Heart Defects, Congenital surgery, Surgeons, Thoracic Surgery
- Abstract
Objectives: We sought to evaluate the predictive power of the Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery (STAT) mortality score and the adult congenital heart surgery (ACHS) mortality score for the adults undergoing congenital heart operations entered into the European Congenital Heart Surgeons Association (ECHSA) database., Methods: The data set comprised 17 662 major operations performed between 1997 and 2019, on patients 18 years of age or older, in European centres participating in the ECHSA database. Each operation was assigned a STAT mortality score and category and an ACHS mortality score. Operative mortality was based on the 30-day status and on the status at hospital discharge. The discriminatory power of the STAT and ACHS scores was assessed using the area under the receiver operating characteristic curve (c-index)., Results: A total of 17 214 (97.46%) operations were assigned ACHS scores. The 3 most frequent primary procedures were closure of the atrial septal defect (19.0%), aortic valve replacement (8.8%) and non-valve-sparing aortic root replacement (6.1%). Operative mortality for ACHS-coded operations was 2.07%. The procedures with the highest mortality were atrial septal defect creation/enlargement (19.0%), lung transplantation (18.8%) and heart transplantation (18.2%). A total of 17 638 (99.86%) operations were assigned a STAT score and category. The operative mortality for STAT-coded operations was 2.27%. The c-index for mortality was 0.720 for the STAT mortality score and 0.701 for the ACHS score., Conclusions: The ACHS mortality score and the STAT mortality score reached similar, moderate predictive power in adult patients undergoing congenital heart surgery in ECHSA database., (© The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
40. Surgical strategies for the management of end-stage heart failure in infants and children: A 15-year experience with a patient-tailored approach.
- Author
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Ponzoni M, Frigo AC, Castaldi B, Cerutti A, Di Salvo G, Vida VL, and Padalino MA
- Subjects
- Child, Child, Preschool, Female, Heart Defects, Congenital surgery, Heart Transplantation statistics & numerical data, Humans, Infant, Male, Pulmonary Artery surgery, Retrospective Studies, Survival Analysis, Treatment Outcome, Ventricular Dysfunction, Left surgery, Cardiomyopathy, Dilated surgery, Heart Failure surgery, Heart-Assist Devices, Postoperative Complications
- Abstract
End-stage heart failure (ESHF) in pediatric age is an ongoing challenge. Heart transplantation is the final option, but its long-term outcomes are still suboptimal in children. An alternative patient-tailored surgical protocol to manage ESHF in children is described. Retrospective, single-center analysis of pediatric patients admitted to our institution between April 2004 and February 2021 for ESHF. Our current protocol is as follows: (a) Patients <1 year with isolated left ventricular dysfunction due to dilated cardiomyopathy underwent pulmonary artery banding (PAB). (b) Patients <10 years and <20 kg, who did not meet previous criteria were managed with Berlin Heart EXCOR. (c) Patients >10 years or >20 kg, underwent placement of intracorporeal Heartware. Primary outcomes were survival, transplant incidence, and postoperative adverse events. A total of 24 patients (mean age 5.3 ± 5.9 years) underwent 26 procedures: PAB in 6 patients, Berlin Heart in 11, and Heartware in 7. Two patients shifted from PAB to Berlin Heart. Overall survival at 1-year follow-up and 5-year follow-up was 78.7% (95%CI = 62%-95.4%) and 74.1% (95%CI = 56.1%-92.1%), respectively. Berlin Heart was adopted in higher-risk settings showing inferior outcomes, whereas a PAB enabled 67% of patients to avoid transplantation, with no mortality. An integrated, patient-tailored surgical strategy, comprehensive of PAB and different types of ventricular assist devices, can provide satisfactory medium-term results for bridging to transplant or recovery. The early postoperative period is critical and requires strict clinical vigilance. Selected infants can benefit from PAB that has demonstrated to be a safe bridge to recovery., (© 2021 The Authors. Artificial Organs published by International Center for Artificial Organ and Transplantation (ICAOT) and Wiley Periodicals LLC.)
- Published
- 2021
- Full Text
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41. The presence of an additional ventricular chamber does not change the outcome of Fontan circulation: a comparative study.
- Author
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Rossi E, Frigo AC, Reffo E, Cabrelle G, Castaldi B, Di Salvo G, Vida VL, and Padalino MA
- Subjects
- Heart Ventricles diagnostic imaging, Heart Ventricles surgery, Humans, Retrospective Studies, Treatment Outcome, Fontan Procedure adverse effects, Heart Defects, Congenital surgery
- Abstract
Objectives: The role of an additional ventricle in patients with a functional single ventricle undergoing the Fontan operation has been debated due to conflicting data. Our goal was to report our experience with Fontan circulation for complex congenital heart disease, with a focus on the influence that an additional ventricular chamber may have on early and long-term clinical outcomes., Methods: We performed a retrospective clinical study including all patients undergoing the Fontan procedure between 1978 and 2019. Clinical data were retrieved from our institutional database. A 'biventricular' Fontan (BVF) was defined as that performed in a patient with single ventricle anomaly where an additional diminutive ventricular cavity was present at echocardiographic evaluation., Results: A total of 210 consecutive patients with functional single ventricle were included. Among these, 46 had BVF (21.9%). Early complications occurred in 42 patients (20.0%; 11 in BVF vs 31 in univentricular Fontan; P = 0.53) There were 18 early deaths (8.6%) with no difference between the groups. At a median follow-up of 12.7 years (interquartile range 5.4-20.7), there were no significant differences in late mortality, whereas cardiac rhythm disturbances resulted more frequently in univentricular Fontan (P = 0.018). Statistical analysis showed an equal distribution of BVF across time (P = 0.620), and there were no significant differences in terms of early and late survival (P = 0.53 and P = 0.72, respectively) or morbidity (P = 0.45 and P = 0.80, respectively)., Conclusions: A secondary ventricle in Fontan circulation is not significantly related to any clinical disadvantage in terms of survival or onset of complications. However, the immediate postoperative course may be influenced negatively by the presence of an additional secondary ventricle., (© The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
42. 3D ultrasound-based fetal heart reconstruction: a pilot protocol in prenatal counselling.
- Author
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Cattapan C, Bertelli F, Guariento A, Andolfatto M, Veronese P, and Vida VL
- Subjects
- Female, Humans, Imaging, Three-Dimensional, Pilot Projects, Pregnancy, Ultrasonography, Ultrasonography, Prenatal, Counseling, Fetal Heart diagnostic imaging
- Published
- 2021
- Full Text
- View/download PDF
43. Anomalous left coronary artery from pulmonary artery repair: Outcomes from the European Congenital Heart Surgeons Association Database.
- Author
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Triglia LT, Guariento A, Zanotto L, Zanotto L, Cattapan C, Hu R, Zhang H, Herbst C, Hörer J, Sarris G, Ebels T, Maruszewski B, Tobota Z, Blitzer D, Lorenzoni G, Bottigliengo D, Gregori D, Padalino M, Di Salvo G, and Vida VL
- Subjects
- Humans, Infant, Infant, Newborn, Pulmonary Artery surgery, Retrospective Studies, Treatment Outcome, Anomalous Left Coronary Artery, Bland White Garland Syndrome, Coronary Vessel Anomalies, Surgeons
- Abstract
Introduction: We sought to determine the surgical outcomes of patients with anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) enrolled in the European Congenital Heart Surgeons Association (ECHSA) database., Materials and Methods: From 1999 to 2019, 907 patients with ALCAPA underwent surgical repair and were included in the current study. The primary outcome was in-hospital mortality. Secondary outcomes included frequency and results of concomitant mitral valve surgery and postoperative mechanical circulatory support (MCS)., Results: The overall in-hospital mortality was 6% (54/907) and was significantly higher in neonates (p = .01), patients with lower body surface area (BSA) (p = .01), and those requiring postoperative MCS (p = .001). Associated mitral valve surgery was performed in 144 patients (15.9%) and was associated with longer cardiopulmonary bypass (CPB) and aortic cross-clamp times (AOX) (p ≤ .0001) but was not significantly related to an increase in in-hospital mortality. Postoperative MCS was required in 66 patients (7.3%). These patients were younger (p ≤ .001), had a lower BSA (p ≤ .001), and required a longer CPB (p ≤ .001) and AOX time (p ≤ .001)., Conclusions: ALCAPA repair can be achieved successfully, and with low surgical risk. Concomitant mitral valve procedures can be performed without increasing operative mortality. The use of MCS remains a valuable option, especially in younger patients., (© 2021 Wiley Periodicals LLC.)
- Published
- 2021
- Full Text
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44. Three-Dimensional Printing of Fetal Heart With d-Transposition of the Great Arteries From Ultrasound Imaging Data.
- Author
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Veronese P, Bertelli F, Cattapan C, Andolfatto M, Gervasi MT, and Vida VL
- Subjects
- Female, Humans, Imaging, Three-Dimensional, Pregnancy, Tomography, X-Ray Computed methods, Fetal Heart diagnostic imaging, Printing, Three-Dimensional, Transposition of Great Vessels diagnosis, Ultrasonography, Prenatal methods
- Abstract
We reconstructed and printed a 3D model of the fetal heart affected by d-transposition of the great arteries from prenatal ultrasound images. Our 3D model revealed to be very helpful in showing the basic anatomical features of fetal complex Congenital Heart Disease (CHD) and represents an interesting additional diagnostic tool to the current standard imaging armamentarium, improving the quality of prenatal parental counseling.
- Published
- 2021
- Full Text
- View/download PDF
45. Changes in minimally invasive congenital cardiac surgery. Moving away from the midline.
- Author
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Guariento A, Doulamis IP, Blitzer D, Cattapan C, Padalino MA, and Vida VL
- Subjects
- Heart, Humans, Cardiac Surgical Procedures, Minimally Invasive Surgical Procedures
- Published
- 2021
- Full Text
- View/download PDF
46. The "Hub and Spoke" (HandS) ECMO for "Resuscitating" Neonates with Respiratory Life-Threatening Conditions.
- Author
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Padalino MA, Doglioni N, Nardo D, Baraldi E, Vida VL, and Trevisanuto D
- Abstract
Background: Extracorporeal membrane oxygenation (ECMO) implantation for neonates with severe cardiorespiratory life-threatening conditions is highly effective. However, since ECMO is a high-risk and complex therapy, this treatment is usually performed in centers with proven expertise., Methods: A retrospective review of neonates, from January 2014 to January 2020, presenting with life-threatening conditions and treated by means of Hub and Spoke (HandS) ECMO in peripheral (spoke) hospitals. Data were retrieved from our internal ECMO registry. Protocols and checklists were revised and shared with all spoke hospitals located in North-Eastern Italy., Results: Eleven neonates receiving maximal respiratory and cardiovascular support at a spoke hospital underwent HandS ECMO management. All but three patients were affected by life-threatening meconium aspiration syndrome (MAS). The median ECMO support duration and hospitalization were four (range 2-32) and 30 days (range 8-50), respectively. All but two patients (with congenital diaphragmatic hernia), were weaned off ECMO and discharged home. At a mean follow up of 33.7 ± 29.2 months, all survivors were alive and well, without medications, and normal somatic growth. All but one had normal neuropsychological development., Conclusion: HandS ECMO model for neonates with life-threatening conditions is effective and successful. A specialized multidisciplinary team and close cooperation between Hub and Spoke centers are essential for success.
- Published
- 2021
- Full Text
- View/download PDF
47. Long-term experience with the one-and-a-half ventricle repair for simple and complex congenital heart defects.
- Author
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Cabrelle G, Castaldi B, Vedovelli L, Gregori D, Vida VL, and Padalino MA
- Subjects
- Child, Preschool, Follow-Up Studies, Humans, Oxygen, Oxygen Consumption, Retrospective Studies, Treatment Outcome, Heart Defects, Congenital surgery, Heart Ventricles diagnostic imaging, Heart Ventricles surgery
- Abstract
Objectives: The one-and-a-half ventricle repair (1.5VR) is a surgical alternative to Fontan circulation or high-risk biventricular repair in patients with complex congenital heart disease (CHD) with a hypoplastic right ventricle (RV). We report our 25 years of experience to evaluate whether the degree of anatomical complexity of the CHD can affect long-term outcomes., Methods: This is a retrospective study including patients undergoing 1.5VR between 1994 and 2018. Clinical records and operative reports were reviewed. Follow-up data were collected from all survivors at the last evaluation or by phone contact., Results: Twenty-nine patients underwent 1.5VR [median age: 3.5 years, interquartile range (IQR) 0.8-7.8]. Fifteen patients had 'simple' (i.e. confined to right heart lesions) anatomical characteristics (48.3%); the median tricuspid valve annulus z-score was -3.5 (IQR -6.2 to +3.6). There were no operative deaths. The median hospital stay was 21 days (IQR 10-33), with postoperative complications in 21 patients (75.8%). At a median follow-up of 13.2 years (IQR 3.2-25.6 years; completeness 96.6%), there were 3 late deaths. There was no significant difference in survival and in freedom from adverse events between simple and complex anatomy groups. However, stress test findings showed a tendency towards a higher maximum oxygen uptake in the simple group (P = 0.055)., Conclusions: The 1.5VR strategy is an effective low-risk surgical option for patients with CHD with hypoplastic RV. When it is planned from birth, late outcomes can be satisfactory. In our experience, the presence of associated major cardiac anomalies was not associated with either worse early or long-term outcomes and functional status., (© The Author(s) 2020. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
48. Evolving Techniques for the Achievement of Optimal Long-Term Results After Tetralogy of Fallot Repair.
- Author
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Stellin G, Guariento A, and Vida VL
- Subjects
- Follow-Up Studies, Humans, Infant, Time Factors, Treatment Outcome, Cardiac Surgical Procedures methods, Pulmonary Valve surgery, Tetralogy of Fallot surgery
- Abstract
Several techniques designed to improve long-term results after repair of tetralogy of Fallot are described. We have recently embarked on a program focused on preserving the native pulmonary valve. Here, combined techniques are described in detail, including intraoperative pulmonary valve balloon dilatation, pulmonary valve reconstruction by delamination and resuspension of the leaflets, and pulmonary valve annulus augmentation. As with any other complex congenital heart disease, senior surgeons should select teaching cases, starting from the less severe side of the spectrum.
- Published
- 2021
- Full Text
- View/download PDF
49. 3D reconstruction for preoperative planning of partial anomalous pulmonary venous return.
- Author
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Guariento A, Cattapan C, Chemello E, Bertelli F, Padalino M, Reffo E, Di Salvo G, Motta R, and Vida VL
- Subjects
- Humans, Imaging, Three-Dimensional, Vena Cava, Superior, Pulmonary Veins diagnostic imaging, Pulmonary Veins surgery, Scimitar Syndrome diagnostic imaging, Scimitar Syndrome surgery
- Published
- 2021
- Full Text
- View/download PDF
50. Early Impact of the COVID-19 Pandemic on Congenital Heart Surgery Programs Across the World: Assessment by a Global Multi-Societal Consortium.
- Author
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Protopapas EM, Rito ML, Vida VL, Sarris GE, Tchervenkov CI, Maruszewski BJ, Tobota Z, Zheleva B, Zhang H, Jacobs JP, Dearani JA, Stephens EH, Tweddell JS, Sandoval NF, Bacha EA, Austin EH, Sakamoto K, Talwar S, Kurosawa H, Halees ZYA, Jatene MB, Iyer KS, Lee C, Sharma R, Hirata Y, Edwin F, Cervantes JL, O'Brien J, St Louis J, and Kirklin JK
- Subjects
- Child, Extracorporeal Membrane Oxygenation statistics & numerical data, Global Health, Health Care Surveys, Humans, Organizational Policy, Patient Care Management statistics & numerical data, SARS-CoV-2, COVID-19, Cardiac Surgical Procedures statistics & numerical data, Elective Surgical Procedures statistics & numerical data, Heart Defects, Congenital surgery, Hospital Administration, Pandemics
- Abstract
The coronavirus disease 2019 (COVID-19) pandemic currently gripping the globe is impacting the entire health care system with rapidly escalating morbidities and mortality. Although the infectious risk to the pediatric population appears low, the effects on children with congenital heart disease (CHD) remain poorly understood. The closure of congenital heart surgery programs worldwide to address the growing number of infected individuals could have an unintended impact on future health for COVID-19-negative patients with CHD. Pediatric and congenital heart surgeons, given their small numbers and close relationships, are uniquely positioned to collectively assess the impact of the pandemic on surgical practice and care of children with CHD. We present the results of an international survey sent to pediatric and congenital heart surgeons characterizing the early impact of COVID-19 on the care of patients with CHD.
- Published
- 2020
- Full Text
- View/download PDF
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