9 results on '"Victoria Kabanova"'
Search Results
2. Ultrafast structural changes direct the first molecular events of vision
- Author
-
Thomas Gruhl, Tobias Weinert, Matthew Rodrigues, Christopher J Milne, Giorgia Ortolani, Karol Nass, Eriko Nango, Saumik Sen, Philip J M Johnson, Claudio Cirelli, Antonia Furrer, Sandra Mous, Petr Skopintsev, Daniel James, Florian Dworkowski, Petra Båth, Demet Kekilli, Dmitry Ozerov, Rie Tanaka, Hannah Glover, Camila Bacellar, Steffen Brünle, Cecilia M Casadei, Azeglio D Diethelm, Dardan Gashi, Guillaume Gotthard, Ramon Guixà-González, Yasumasa Joti, Victoria Kabanova, Gregor Knopp, Elena Lesca, Pikyee Ma, Isabelle Martiel, Jonas Mühle, Shigeki Owada, Filip Pamula, Daniel Sarabi, Oliver Tejero, Ching-Ju Tsai, Niranjan Varma, Anna Wach, Sébastien Boutet, Kensuke Tono, Przemyslaw Nogly, Xavier Deupi, So Iwata, Richard Neutze, Jörg Standfuss, Gebhard FX Schertler, and Valerie Panneels
- Subjects
basis-sets ,Multidisciplinary ,software ,energy-storage ,dynamics ,Photobiology ,isomerization ,rhodopsin ,excited-state ,retinal chromophore ,counterion displacement ,Visual system ,crystallography ,X-ray crystallography - Abstract
Vision is initiated by the rhodopsin family of light-sensitive G protein-coupled receptors (GPCRs). A photon is absorbed by the 11-cis retinal chromophore of rhodopsin, which isomerizes within 200 femtoseconds to the all-trans conformation, thereby initiating the cellular signal transduction processes that ultimately lead to vision. However, the intramolecular mechanism by which the photoactivated retinal induces the activation events inside rhodopsin remains experimentally unclear. Here we use ultrafast time-resolved crystallography at room temperature to determine how an isomerized twisted all-trans retinal stores the photon energy that is required to initiate the protein conformational changes associated with the formation of the G protein-binding signalling state. The distorted retinal at a 1-ps time delay after photoactivation has pulled away from half of its numerous interactions with its binding pocket, and the excess of the photon energy is released through an anisotropic protein breathing motion in the direction of the extracellular space. Notably, the very early structural motions in the protein side chains of rhodopsin appear in regions that are involved in later stages of the conserved class A GPCR activation mechanism. Our study sheds light on the earliest stages of vision in vertebrates and points to fundamental aspects of the molecular mechanisms of agonist-mediated GPCR activation., 視覚に関わるタンパク質の超高速分子動画 --薄暗いところで光を感じる仕組み--. 京都大学プレスリリース. 2023-03-23.
- Published
- 2023
3. Revealing Hot and Long-Lived Metastable Spin States in the Photoinduced Switching of Solvated Metallogrid Complexes with Femtosecond Optical and X-ray Spectroscopies
- Author
-
Maria Naumova, Jie Meng, Jianxin Zhang, Peter Zalden, David J. Gosztola, Franc Meyer, Katharina Kubicek, Christian Bressler, Stefano Checchia, Mohamed Abdellah, Matthias Bauer, Michael Wulff, Dirk Schwarzer, Martin Jarenmark, Edoardo Domenichini, Max Latevi Lawson Daku, Sophie E. Canton, Weihua Lin, Alexander Britz, Frederico A. Lima, Joanne W. L. Wong, Wojciech Gawelda, Aleksandr Kalinko, Pierre-Adrien Mante, Serhiy Demeshko, Sol Alvarez Gutierrez, Vadim Murzin, Dmitry Khakhulin, Andreas Galler, Huifang Geng, Kaibo Zheng, Victoria Kabanova, Jennifer Zimara, and Mykola Biednov
- Subjects
Materials science ,Spin states ,Kinetics ,02 engineering and technology ,Ligands ,010402 general chemistry ,Quantum mechanics Kinetics ,01 natural sciences ,Metal ,Spin chemistry ,Metastability ,X-rays ,ddc:530 ,General Materials Science ,Physical and Theoretical Chemistry ,Oscillation ,021001 nanoscience & nanotechnology ,3. Good health ,0104 chemical sciences ,Chemical physics ,visual_art ,Femtosecond ,visual_art.visual_art_medium ,Absorption (chemistry) ,0210 nano-technology - Abstract
An atomistic understanding of the photoinduced spin-state switching (PSS) within polynuclear systems of d4-d7 transition metal ion complexes is required for their rational integration into light-driven reactions of chemical and biological interest. However, in contrast to mononuclear systems, the multidimensional dynamics of the PSS in solvated molecular arrays have not yet been elucidated due to the expected complications associated with the connectivity between the metal centers and the strong interactions with the surroundings. In this work, the PSS in a solvated triiron(II) metallogrid complex is characterized using transient optical absorption and X-ray emission spectroscopies on the femtosecond time scale. The complementary measurements reveal the photoinduced creation of energy-rich (hot) and long-lived quintet states, whose dynamics differ critically from their mononuclear congeners. This finding opens major prospects for developing novel schemes in solution-phase spin chemistry that are driven by the dynamic PSS process in compact oligometallic arrays.
- Published
- 2020
4. From Femtosecond Excited-State and Dissociation Dynamics to Nanosecond Reaction Kinetics: Following C-H Bond Activation with X-rays
- Author
-
Raphael M. Jay, Ambar Banerjee, Torsten Leitner, Robert Stefanuik, Ru-Pan Wang, Jessica Harich, Emma Beale, Victoria Kabanova, Abdullah Kahraman, Anna Wach, Dimitri Ozerov, Christopher A. Arrell, Philip J. M. Johnson, Grigory Smolentsev, Thomas Huthwelker, Camilia N. Borca, Claudio Cirelli, Camila Bacellar, Christopher J. Milne, Nils Huse, Michael Odelius, and Philippe Wernet
- Abstract
Using ultrafast X-ray absorption spectroscopy, we observe how a rhodium carbonyl catalyst is formed on femtosecond timescales and reveal the decisive orbital interactions which facilitate the efficient cleavage of an alkane C-H bond from solution.
- Published
- 2022
5. Structural dynamics probed by X-ray pulses from synchrotrons and XFELs
- Author
-
Friedrich Schotte, Hyotcherl Ihee, Dmitry Khakhulin, Savo Bratos, Matteo Levantino, Anton Plech, Victoria Kabanova, Marco Cammarata, Qingyu Kong, Michael Wulff, and Philip A. Anfinrud
- Subjects
Technology ,Electron transfer ,Materials science ,Scattering ,Femtosecond ,X-ray crystallography ,General Physics and Astronomy ,Synchrotron radiation ,Atomic physics ,ddc:600 ,Diatomic molecule ,Storage ring ,Dissociation (chemistry) - Abstract
This review focuses on how short X-ray pulses from synchrotrons and XFELs can be used to track light-induced structural changes in molecular complexes and proteins via the pump–probe method. The upgrade of the European Synchrotron Radiation Facility to a diffraction-limited storage ring, based on the seven-bend achromat lattice, and how it might boost future pump–probe experiments are described. We discuss some of the first X-ray experiments to achieve 100 ps time resolution, including the dissociation and in-cage recombination of diatomic molecules, as probed by wide-angle X-ray scattering, and the 3D filming of ligand transport in myoglobin, as probed by Laue diffraction. Finally, the use of femtosecond XFEL pulses to investigate primary chemical reactions, bond breakage and bond formation, isomerisation and electron transfer are discussed.
- Published
- 2021
- Full Text
- View/download PDF
6. Taking a snapshot of the triplet excited state of an OLED organometallic luminophore using X-rays
- Author
-
Matteo Levantino, Andrea Cannizzo, R. Bohinc, Michela Gazzetto, Daniel James, Jakub Szlachetko, Camila Bacellar, Alexander A. Guda, Sergey Yu. Ketkov, Kristoffer Haldrup, Martin Beck, Mathias Sander, Marian Olaru, Georgios Pamfilidis, Jens Beckmann, Claudio Cirelli, Victoria Kabanova, Elena Rychagova, Nicolo Azzaroli, Victor V. Shapovalov, Samuel Menzi, Joanna Czapla-Masztafiak, Andrei A. Tereshchenko, Giulia F. Mancini, Aldo Mozzanica, Christopher J. Milne, Wojciech M. Kwiatek, Grigory Smolentsev, Matthias Vogt, Gregor Knopp, and Dardan Gashi
- Subjects
basis-sets ,absorption spectroscopy ,Materials science ,electronic-structure ,Photochemistry ,530 Physics ,Science ,activated delayed fluorescence ,General Physics and Astronomy ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,Article ,General Biochemistry, Genetics and Molecular Biology ,law.invention ,chemistry.chemical_compound ,law ,540 Chemistry ,OLED ,lcsh:Science ,Structural rigidity ,Multidisciplinary ,Scattering ,light-emitting-diodes ,solvation dynamics ,Excited states ,transition ,General Chemistry ,021001 nanoscience & nanotechnology ,Laser ,620 Engineering ,Fluorescence ,emission spectroscopy ,0104 chemical sciences ,chemistry ,Chemical physics ,Excited state ,Luminophore ,systems ,lcsh:Q ,0210 nano-technology ,Excitation ,metal-complexes - Abstract
OLED technology beyond small or expensive devices requires light-emitters, luminophores, based on earth-abundant elements. Understanding and experimental verification of charge transfer in luminophores are needed for this development. An organometallic multicore Cu complex comprising Cu–C and Cu–P bonds represents an underexplored type of luminophore. To investigate the charge transfer and structural rearrangements in this material, we apply complementary pump-probe X-ray techniques: absorption, emission, and scattering including pump-probe measurements at the X-ray free-electron laser SwissFEL. We find that the excitation leads to charge movement from C- and P- coordinated Cu sites and from the phosphorus atoms to phenyl rings; the Cu core slightly rearranges with 0.05 Å increase of the shortest Cu–Cu distance. The use of a Cu cluster bonded to the ligands through C and P atoms is an efficient way to keep structural rigidity of luminophores. Obtained data can be used to verify computational methods for the development of luminophores., Nature Communications, 11 (1), ISSN:2041-1723
- Published
- 2020
- Full Text
- View/download PDF
7. Initial metal–metal bond breakage detected by fs X-ray scattering in the photolysis of Ru 3 (CO) 12 in cyclohexane at 400 nm
- Author
-
Kelly J. Gaffney, T. van Driel, Kristoffer Haldrup, Martin Nielsen, Savo Bratos, Kasper S. Kjær, Dmitry Khakhulin, Elisa Biasin, Michael Wulff, Victoria Kabanova, M. H. J. Koch, Qingyu Kong, Mads G. Laursen, Rodolphe Vuilleumier, and Tsu-Chien Weng
- Subjects
Materials science ,Ligand ,Photodissociation ,Infrared spectroscopy ,Bridging ligand ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Photochemistry ,01 natural sciences ,Chemical reaction ,0104 chemical sciences ,Transition metal ,Picosecond ,Physical and Theoretical Chemistry ,0210 nano-technology ,Bond cleavage - Abstract
Using femtosecond resolution X-ray solution scattering at a free electron laser we were able to directly observe metal-metal bond cleavage upon photolysis at 400 nm of Ru3(CO)12, a prototype for the photochemistry of transition metal carbonyls. This leads to the known single intermediate Ru3(CO)11(μ-CO)*, with a bridging ligand (μCO) and where the asterisk indicates an open Ru3-ring. This loses a CO ligand on a picosecond time scale yielding a newly observed triple bridge intermediate, Ru3(CO)8(μ-CO)3*. This loses another CO ligand to form the previously observed Ru3(CO)10, which returns to Ru3(CO)12 via the known single-bridge Ru3(CO)10(μ-CO). These results indicate that contrary to long standing hypotheses, metal-metal bond breakage is the only chemical reaction immediately following the photolysis of Ru3(CO)12 at 400 nm. Combined with previous picosecond resolution X-ray scattering data and time resolved infrared spectroscopy these results yield a new mechanism for the photolysis of Ru3(CO)12.
- Published
- 2019
- Full Text
- View/download PDF
8. Demonstration of a picosecond Bragg switch for hard x-rays in a synchrotron-based pump-probe experiment
- Author
-
Peter Gaal, Matteo Levantino, D. Pfuetzenreuter, Mathias Sander, Michael Wulff, Jutta Schwarzkopf, Victoria Kabanova, and R. Bauer
- Subjects
Nuclear and High Energy Physics ,Materials science ,Astrophysics::High Energy Astrophysical Phenomena ,FOS: Physical sciences ,Physics::Optics ,02 engineering and technology ,Epitaxy ,Diffraction efficiency ,01 natural sciences ,law.invention ,Optics ,law ,0103 physical sciences ,Instrumentation ,010302 applied physics ,Condensed Matter - Materials Science ,Radiation ,business.industry ,Materials Science (cond-mat.mtrl-sci) ,Pulse duration ,021001 nanoscience & nanotechnology ,Synchrotron ,Pulse (physics) ,Temporal resolution ,Picosecond ,Nanometre ,0210 nano-technology ,business - Abstract
A benchmark experiment is reported that demonstrates the shortening of hard X-ray pulses in a synchrotron-based optical pump–X-ray probe measurement. The pulse-shortening device is a photoacoustic Bragg switch that reduces the temporal resolution of an incident X-ray pulse to approximately 7.5 ps. The Bragg switch is employed to monitor propagating sound waves in nanometer thin epitaxial films. From the experimental data, the pulse duration, diffraction efficiency and switching contrast of the device can be inferred. A detailed efficiency analysis shows that the switch can deliver up to 109 photons s−1 in high-repetition-rate synchrotron experiments.
- Published
- 2018
9. Simulations of single-pulse Laue diffraction from proteins with radiation from synchrotron and XFEL sources
- Author
-
Michael Wulff, Marius Schmidt, Friedrich Schotte, Victoria Kabanova, and Marco Cammarata
- Subjects
Materials science ,business.industry ,Single pulse ,Radiation ,Condensed Matter Physics ,Biochemistry ,Synchrotron ,law.invention ,Inorganic Chemistry ,Crystallography ,Optics ,Structural Biology ,law ,X-ray crystallography ,Radiation damage ,General Materials Science ,Physical and Theoretical Chemistry ,business - Published
- 2016
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.